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11. Prevention of Dermatophytoses

Author

Maruyama, Ryuji, primary, Fukuyama, Kunitaro, additional, Katoh, Takuro, additional, Sugimoto, Rie, additional, Taniguchi, Hiroko, additional, Watanabe, Kyoko, additional, and Nishioka, Kiyoshi, additional

Published
2003
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42. Allergic photocontact dermatitis due to suprofen. Photopatch testing and cross-reaction study.

Author

Kuruma, Yuko, Ohshiro, Yukako, Miyamoto, Chizu, Keong, Chis-Hual, Katoh, Takuro, and Nishoka, Kiyoshi

Subjects
SKIN inflammation, NONSTEROIDAL anti-inflammatory agents, OINTMENTS, ULTRAVIOLET radiation, SUPROFEN, DRUGS
Abstract

We report 5 cases of photocontact dermatitis due to suprofen, a nonsterioidal anti-inflammatory drug introduced to the Japanese market in 1989, and available as a 1% ointment. The patients developed pruritic eczematous lesions after applying the ointment for from 2 weeks to 3 months. All 5 patients reacted positively to photopatch testing with ultraviolet A (UVA) and suprofen down to 0.1-0.01% pet., and 3 patients showed positive reactions with ultraviolet B (UVB) and suprofen down to 1.0-0.1%. Moreover, all patients showed a cross-reaction with tiaprofenic acid, which has a very similar chemical structure to suprofen. However, there was no cross-reaction between suprofen and ketoprofen. Prescribers should be aware of the existence of photocontact sensitivity due to these drugs. [ABSTRACT FROM AUTHOR]

Published
1991
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43. Taste Disorders in Healthy “Carriers” and “Non‐Carriers” of Candida albicansand in Patients with Candidosis of the Tongue

Author

Sakashita, Sayuri, Takayama, Kaoru, Nishioka, Kiyoshi, and Katoh, Takuro

Abstract

Impairments in taste perception may be caused by a number of factors, including the presence of Candida albicansin the oral cavity. We attempted to establish whether the presence of Candida albicanson the tongue is a cause of taste disorders by studying taste disorders in patients with candidosis of the tongue and in healthy “carriers” and “non‐carriers” of C. albicans.Taste disorders and their severity were objectively assessed by the filter‐paper disk method in 18 patients with candidosis of the tongue and in 33 healthy “carriers” and 167 healthy “non‐carriers” of C. albicans.The gustatory function was re‐tested in 7 patients and 8 “carriers” after treatment with topical anti‐mycotic medication to detect any improvement. Patients with candidosis of the tongue and “carriers” of C. albicansdemonstrated significantly higher incidences (p<0.001) of taste disorders than did “non‐carriers”. The mean taste threshold of each of the four individual taste qualities was significantly higher in patients with candidosis than in “non‐carriers”. The average taste threshold was significantly higher in “carriers” than in “non‐carriers”. Post‐treatment improvement or recovery from taste disorders was obtained in 5 out of 7 patients (71.4%) with candidosis and in 7 out of 8 “carriers” (87.5%) of C. albicans.This study clearly demonstrates that not only overt candidosis of the tongue but also commensal harboring of ***C. albicansis a cause of taste disorders.

Published
2004
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44. A Case of Unna‐Thost Disease Accompained by Epidermophyton floccosumInfection

Author

Maruyama, Ryuji, Katoh, Takuro, and Nishioka, Kiyoshi

Abstract

We report herein a case of 61‐year‐old man with Unna‐Thost disease (nonepidermolytic hereditary palmoplantar keratoderma) who had been suffering from refractory dermatophyte infection. Diffuse palmoplantar hyperkeratosis developed in his infancy. Coarse scaling, fissures, marked erythema, and nail deformities appeared in his early adult life. Microscopic examination revealed fungal elements in scales and nail particles. Cultures of those scales isolated Epidermophyton floccosum. Genealogical study demonstrated that his mother, sister, brother, daughter, and niece had had similar tylosis, and all of the affected individuals except his daughter had been proved to have E. floccosumor Trichophyton rubruminfection. Oral itraconazole (100mg/day) was highly effective in treating his dermatophytosis without any adverse effects. Scaling, fissures and underlying erythema disappeared within four months.

Published
1999
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45. Tinea Corporis Due to Microsporum canisfrom an Asymptomatic Dog

Author

Katoh, Takuro, Maruyama, Rhuji, Nishioka, Kiyoshi, and Sano, Takao

Abstract

The patient was a 19‐year‐old female student who purchased a puppy from a pet shop four weeks earlier. At the time of her first examination, an annular edematous erythema with adherent scales and vesicles surrounding its margin was seen on the left forearm. On direct examination of the vesicles, fungal elements were detected, and Microsporum caniswas isolated. The puppy was a Pomeranian and was kept in the house at all times. No clinical lesions were seen on the puppy, and the Wood's lamp test was negative. However, M. caniswas isolated from the animal by the hairbrush method. Symptoms disappeared after the patient was treated topically with terbinafine cream for three weeks. Although the dog received no treatment whatsoever, there was no evidence of the disease on the pet. Results of the hairbrush method performed on the pet two and three weeks later were negative, but, at five weeks, it was again positive. Human infection with M. canisfrom an asymptomatic dog was demonstrated in this case. Attention should be paid to preventing infections from animals without lesions.

Published
1991
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46. Isolations of dermatophyte from clinically normal scalps in M. Canis infections using the hairbrush method.

Author

Katoh, Takuro, Sano, Takao, and Kagawa, Saburo

Abstract

The scalp hair of patients with dermatophytosis due to M. canis but without scalp lesions, and that of their family members without dermatophytosis were examined using the hairbrush method. The dermatophyte was detected in 93.8% of the scalps of those who lived in homes where cats were kept, and in 25% of those without cats. After the source of infection had been treated, the dermatophyte showed a gradually decreasing presence, finally disappearing altogether, so that no case of the disease on the scalp hair could be found. We inferred from the above findings in M. canis infections that, since the dermatophytes are seen in a high proportion of cases without scalp lesions, the dermatophytes, in many cases, exist only as saprophytes on the hair. [ABSTRACT FROM AUTHOR]

Published
1990
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