61 results on '"Katerina Dodelzon"'
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2. Splice isoforms of the polyglutamine disease protein ataxin-3 exhibit similar enzymatic yet different aggregation properties.
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Ginny Marie Harris, Katerina Dodelzon, Lijie Gong, Pedro Gonzalez-Alegre, and Henry L Paulson
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Medicine ,Science - Abstract
Protein context clearly influences neurotoxicity in polyglutamine diseases, but the contribution of alternative splicing to this phenomenon has rarely been investigated. Ataxin-3, a deubiquitinating enzyme and the disease protein in SCA3, is alternatively spliced to encode either a C-terminal hydrophobic stretch or a third ubiquitin interacting motif (termed 2UIM and 3UIM isoforms, respectively). In light of emerging insights into ataxin-3 function, we examined the significance of this splice variation. We confirmed neural expression of several minor 5' variants and both of the known 3' ataxin-3 splice variants. Regardless of polyglutamine expansion, 3UIM ataxin-3 is the predominant isoform in brain. Although 2UIM and 3UIM ataxin-3 display similar in vitro deubiquitinating activity, 2UIM ataxin-3 is more prone to aggregate and more rapidly degraded by the proteasome. Our data demonstrate how alternative splicing of sequences distinct from the trinucleotide repeat can alter properties of the encoded polyglutamine disease protein and thereby perhaps contribute to selective neurotoxicity.
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- 2010
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3. Axillary Lymphadenopathy After a COVID-19 Vaccine Booster Dose: Time to Resolution on Ultrasound Follow-Up and Associated Factors
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Eralda Mema, Elizabeth G. Lane, Michele B. Drotman, Carolyn S. Eisen, Charlene Thomas, Martin R. Prince, and Katerina Dodelzon
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Radiology, Nuclear Medicine and imaging ,General Medicine - Published
- 2023
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4. Ongoing Impact of COVID-19 on Breast Radiologists’ Wellness
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Katerina Dodelzon, Lars J Grimm, S Reed Plimpton, Daniela Markovic, and Hannah S Milch
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Abstract
Objective Assess the ongoing impact of COVID-19 on mental well-being of breast radiologists nationwide two years after the start of the pandemic and compared to early in the pandemic. Methods A 27-question survey was distributed from December 2021 to January 2022 to physician members of the Society of Breast Imaging. Psychological distress and anxiety scores were calculated, and factors associated with them were identified with a multivariate logistic model. Results A total of 550 surveys were completed (23% response rate); the mean respondent age was 50 +/− 10 years. Fifty percent (265/526) of respondents reported two or more psychological distress symptoms, down from 58% in 2020 (P = 0.002), whereas 70% (362/526) of respondents reported increased anxiety, down from 82% in 2020 (P Conclusion The COVID-19 pandemic continues to cause mental health symptoms in breast radiologists, especially for those with pandemic-specific childcare needs and financial distress. Pandemic-related decreased opportunities to connect with patients and colleagues negatively impacts radiologists’ mental health.
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- 2023
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5. State of Communication Training During the Breast Imaging Fellowship Year
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Janine Katzen and Katerina Dodelzon
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Abstract
Objective The purpose of this study was to survey breast imaging fellowship programs nationally on the state of communication skills training during fellowship training. Methods In this IRB-exempt study, fellowship program director members of the Society of Breast Imaging (SBI) were anonymously surveyed on current provision and types of communication skills training in their fellowship curricula. Results A six-question survey was sent to all 95 SBI member fellowship program directors with a response rate of 56% (53/95). Although direct fellow patient-centered communication interactions are practiced across all respondent training programs, formal communication skills training was offered in a minority of programs with 32% (17/53) providing formal communication in the form of a didactic lecture and 17% (9/53) engaging fellows in a simulation communication skills workshop. Of the 53 programs, 12 (22%) reported no formal communication skills training of any kind, while a majority (44/53, 83%) of programs provide regular feedback based on observed fellow–patient communication interactions. Conclusion Despite nearly uniform practice of engaging breast imaging fellows in direct patient-centered interaction at the onset of the fellowship training year, the majority of fellowship programs do not provide any formal communication skills training curricula at any point during fellowship training. To equip future breast radiologists with the skills to provide value in an increasingly patient-centered field, dedicated formal communication curricula ought to be incorporated consistently into breast imaging fellowship training programs.
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- 2023
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6. Axillary lymphadenopathy on breast imaging following the administration of inactivated polio vaccine
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Elizabeth G. Lane, Katerina Dodelzon, Katherine Simon, and Kemi Babagbemi
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Radiology, Nuclear Medicine and imaging - Published
- 2023
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7. Time for Resolution of COVID-19 Vaccine–Related Axillary Lymphadenopathy and Associated Factors
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Elizabeth G. Lane, Carolyn S. Eisen, Michele B. Drotman, Katerina Dodelzon, Eralda Mema, Charlene Thomas, and Martin R. Prince
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Adult ,COVID-19 Vaccines ,COVID-19 ,Lymphadenopathy ,Breast Neoplasms ,General Medicine ,Middle Aged ,Lymphatic Metastasis ,Humans ,Female ,Radiology, Nuclear Medicine and imaging ,RNA, Messenger ,Early Detection of Cancer ,Mammography ,Retrospective Studies - Published
- 2022
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8. Patient-centered Care: Value Added by Breast Radiologists in the Management of Breast Pain
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Katerina Dodelzon, Shreena Shah, Lona Prasad, Juliana Atallah, and Janine T Katzen
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Abstract
With the shift of the healthcare system toward patient-centered, value-based care, the role of the breast radiologist is essential and increasingly multifaceted. Beyond sole image interpreters, breast radiologists serve as subject matter experts within multidisciplinary care teams, acting as advocates and initiators into the healthcare system and providing patient-centered care through effective communication and patient education. These vital roles are well demonstrated through the imaging evaluation and management of the most common breast symptom that affects the majority of the patient population—mastalgia. By leveraging the opportunities provided during the evaluation of the symptomatic breast to optimize patient communication and education, as well as integration of care delivery, breast radiologists add significant value to patient care and ultimately improve patient outcomes.
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- 2023
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9. Bleeding Events After Image-Guided Breast Biopsies: Comparison of Patients Temporarily Discontinuing Versus Maintaining Antithrombotic Therapy During Biopsy
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Melissa Reichman, Paige McMahon, Michaela Dwyer, Se Jung Chang, Hung Lin, Janine Katzen, Charlene Thomas, Michele Drotman, and Katerina Dodelzon
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Radiology, Nuclear Medicine and imaging ,General Medicine - Published
- 2023
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10. Active surveillance of atypical ductal hyperplasia of the breast
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Lynn K Han, Anum Hussain, Katerina Dodelzon, Paula S Ginter, William S Towne, and Jennifer L Marti
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Cancer Research ,Oncology - Published
- 2023
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11. Bleeding Complications After Breast Core-needle Biopsy—An Approach to Managing Patients on Antithrombotic Therapy
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Sally Goudreau, Lars J Grimm, Ashmitha Srinivasan, Jose Net, Roger Yang, Vandana Dialani, and Katerina Dodelzon
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Abstract
Image-guided core-needle breast and axillary biopsy (CNB) is the standard-of-care procedure for the diagnosis of breast cancer. Although the risks of CNB are low, the most common complications include bleeding and hematoma formation. Post-procedural bleeding is of particular concern in patients taking antithrombotic therapy, but there is currently no widely established standard protocol in the United States to guide antithrombotic therapy management. In the face of an increasing number of patients taking antithrombotic therapy and with the advent of novel classes of anticoagulants, the American College of Radiology guidelines recommend that radiologists consider cessation of antithrombotic therapy prior to CNB on a case-by-case basis. Lack of consensus results in disparate approaches to patients on antithrombotic therapy undergoing CNB. There is further heterogeneity in recommendations for cessation of antithrombotic therapy based on the modality used for image-guided biopsy, target location, number of simultaneous biopsies, and type of antithrombotic agent. A review of the available data demonstrates the safety of continuing antithrombotic therapy during CNB while highlighting additional procedural and target lesion factors that may increase the risk of bleeding. Risk stratification of patients undergoing breast interventional procedures is proposed to guide both pre-procedural decision-making and post-procedural management. Radiologists should be aware of antithrombotic agent pharmacokinetics and strategies to minimize post-procedural bleeding to safely manage patients.
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- 2022
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12. Communicating With Breast Imaging Patients During the COVID-19 Pandemic: Impact on Patient Care and Physician Wellness
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Hannah S Milch, Lars J Grimm, Steven R Plimpton, Khai Tran, Daniela Markovic, Brian N Dontchos, Stamatia Destounis, Vandana Dialani, Basak E Dogan, Emily B Sonnenblick, Margarita L Zuley, and Katerina Dodelzon
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Abstract
Objective Assess the impact of COVID-19 on patient-breast radiologist interactions and evaluate the relationship between safety measure–constrained communication and physician wellbeing. Methods A 41-question survey on the perceived effect of COVID-19 on patient care was distributed from June 2020 to September 2020 to members of the Society of Breast Imaging and the National Consortium of Breast Centers. Non-radiologists and international members were excluded. Anxiety and psychological distress scores were calculated. A multivariable logistic model was used to identify demographic and mental health factors associated with responses. Results Five hundred twenty-five surveys met inclusion criteria (23% response rate). Diminished ability to fulfill patients’ emotional needs was reported by 46% (221/479), a response associated with younger age (OR, 0.8 per decade; P Conclusion The majority of breast radiologists reported that COVID-19 has had a negative impact on patient care. This perception was more likely among younger radiologists and those with higher levels of anxiety and psychological distress.
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- 2022
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13. Variations and Challenges to Performing Outside Study Interpretations in Breast Imaging: A National Survey of the Society of Breast Imaging Membership
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Brian N Dontchos, Katerina Dodelzon, Basak E Dogan, Emily B Sonnenblick, Stamatia Destounis, Roger Yang, Vandana Dialani, Vidushani Perera, and Lars J Grimm
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Abstract
Objective Second-opinion interpretations of outside facility breast imaging provide value-added care but are operationally challenging for breast radiologists. Our objective was to survey members of the Society of Breast Imaging (SBI) to assess practice patterns and perceived barriers to performing outside study interpretations (OSIs). Methods An anonymous survey was developed by the Patient Care and Delivery Committee of the SBI and distributed via e-mail to SBI radiologist members. Survey questions included practice demographics and OSI volumes, billing practices, clinical scenarios, and imaging modalities, logistics, and barriers. Responses were aggregated and comparisons were made by univariate analysis using likelihood ratio tests, t-tests, and Spearman’s rank correlation tests as appropriate. Ordinal or nominal logistic modeling and linear regression modeling was also performed. Results There were 371 responses (response rate of 13%). Most respondents practice at an affiliated specialty breast care center (306/371, 83%) and said their practice performed OSIs (256/371, 69%). Academic practices reported the highest OSI volumes (median 75 per month) and were most likely to indicate increases in OSI volumes over time (100/144, 69%). The most common indication for OSI was second opinion for a biopsy recommendation (245/256, 96%). Most practices provide a final BI-RADS assessment (183/261, 70%). The most cited barrier to performing OSIs was physician time constraints (252/369, 68%). Conclusion Breast imaging OSI practice patterns are variable among SBI members with notable differences by practice setting and multiple barriers identified. More unified guidelines and recommendations may be needed for radiologists to better perform this valuable task.
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- 2022
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14. Transient ipsilateral breast edema following COVID-19 vaccination
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Anika L, McGrath, Michele B, Drotman, and Katerina, Dodelzon
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Breast Diseases ,COVID-19 Vaccines ,Vaccination ,COVID-19 ,Edema ,Humans ,Breast Neoplasms ,Female ,Radiology, Nuclear Medicine and imaging - Abstract
While ipsilateral lymphadenopathy following COVID-19 vaccination is a relatively common finding on mammography and breast ultrasound transient ipsilateral breast edema is rare with only a few published case reports. Radiologists should be aware of this potential imaging appearance of the breast and axilla following COVID-19 vaccination given the imaging features of edema such as trabecular thickening, skin thickening, and increased echogenicity can overlap with benign and malignant breast conditions such as mastitis and inflammatory breast cancer. We describe a case of transient ipsilateral breast edema after COVID-19 vaccination followed by a discussion summarizing the current understanding and management of transient ipsilateral breast edema following COVID-19 vaccination.
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- 2022
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15. Bilateral Breast Non-mass Enhancement Due to Chronic Lymphocytic Leukemia
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Marina J Corines and Katerina Dodelzon
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Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Published
- 2023
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16. Unilateral axillary adenopathy in the setting of COVID-19 vaccine: Follow-up
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Rachel Marcus Sales, Kemi Babagbemi, Michele Drotman, Katerina Dodelzon, Anika L. McGrath, Allison D. Levy, and Nishi Mehta
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medicine.medical_specialty ,COVID-19 Vaccines ,Coronavirus disease 2019 (COVID-19) ,Breast imaging ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Population ,Lymphadenopathy ,Breast Neoplasms ,Unilateral axillary Adenopathy ,medicine ,Humans ,Mammography ,Radiology, Nuclear Medicine and imaging ,education ,Axillary Adenopathy ,Early Detection of Cancer ,Vaccines ,education.field_of_study ,Routine screening ,medicine.diagnostic_test ,SARS-CoV-2 ,business.industry ,Breast Imaging ,General surgery ,COVID-19 ,Current management ,Screening ,Female ,business ,Vaccine ,Follow-Up Studies - Abstract
With the Pfizer-BioNTech, Moderna, and now Johnson and Johnson COVID-19 vaccines readily available to the general population, the appearance of vaccine-induced axillary adenopathy on imaging has become more prevalent. We are presenting follow up to the first reported four cases of vaccine induced unilateral axillary adenopathy on imaging to our knowledge, which demonstrate expected self-resolving adenopathy. Our hope is that by providing this follow-up and reviewing current management guidelines, clinicians as well as patients will appreciate that this is an expected, benign, and self-resolving finding. In addition, we hope to quell any vaccine hesitancy brought about by recent mainstream media attention to this topic and ultimately empower patients to receive both the COVID-19 vaccine and undergo routine screening mammography, as both are vital to their health.
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- 2021
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17. Mode of detection matters: Differences in screen-detected versus symptomatic breast cancers
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Anna Starikov, Anthony Blackburn, Connie Moying Lu, Elizabeth Kagan Arleo, Katerina Dodelzon, Elizabeth Reznik, Esther Cheng, Gulce Askin, Julie Kim, and Arpita Bose
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medicine.medical_specialty ,Chemotherapy ,business.industry ,medicine.medical_treatment ,Lumpectomy ,Breast Neoplasms ,Histology ,Retrospective cohort study ,Disease ,medicine.disease ,Gastroenterology ,Exact test ,Breast cancer ,Internal medicine ,medicine ,Humans ,Mass Screening ,Female ,Radiology, Nuclear Medicine and imaging ,Stage (cooking) ,business ,Early Detection of Cancer ,Mammography ,Retrospective Studies - Abstract
OBJECTIVE Although extensive analyses evaluating screening mammography for breast cancer have been published, some utilized databases do not distinguish between modes of detection, which confounds the conclusions made about the impact of screening mammography. METHODS A retrospective cohort study of women at our institution with pathologically-proven breast cancer from January 2015 to April 2018 was conducted. Subjects were categorized by their mode of diagnosis: screening or non-screening. Patient demographics, tumor characteristics, and treatments were compared between detection methods using Wilcoxon rank-sum test for continuous variables and chi-squared or Fisher's exact test. RESULTS 1026 breast cancers were analyzed. 80.8% of screen-detected breast cancers were invasive. Compared to symptomatically detected cancers, screen-detected were smaller (median size 8 mm vs. 15 mm, p
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- 2021
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18. Axillary Imaging Following a New Invasive Breast Cancer Diagnosis—A Radiologist’s Dilemma
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Neha Modi, Brian N. Dontchos, Basak E. Dogan, Vandana Dialani, Katerina Dodelzon, and Lars J. Grimm
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medicine.medical_specialty ,Radiological and Ultrasound Technology ,business.industry ,medicine.disease ,Dilemma ,Axilla ,medicine.anatomical_structure ,Breast cancer ,Medical imaging ,medicine ,Radiology, Nuclear Medicine and imaging ,Radiology ,Lesch–Nyhan syndrome ,business - Abstract
Traditionally, patients with newly diagnosed invasive breast cancer underwent axillary US to assess for suspicious axillary lymph nodes (LNs), which were then targeted for image-guided needle biopsy to determine the presence of metastasis. Over the past decade, there has been a shift towards axillary preservation. For patients with palpable lymphadenopathy, the decision to perform axillary imaging with documentation of the number and location of abnormal LNs in preparation for image-guided LN sampling is straightforward. Since LN involvement correlates with cancer size, it is reasonable to image the axilla in patients with tumors larger than 5 cm; however, for tumors smaller than 5 cm, axillary imaging is often deferred until after the tumor molecular subtype and treatment plan are established. Over the last decade, neoadjuvant chemotherapy (NACT) is increasingly used for smaller cancers with more aggressive molecular subtypes. In most cases, detecting axillary metastasis is critical when deciding whether the patient would benefit from NACT. There is increasing evidence that abnormal axillary US findings correlates with LN metastases and reliably establishes a baseline to monitor response to NACT. Depending on hormone receptor status, practices may choose to image the axilla in the setting of clinical stage T1 and T2 cancers to evaluate nodal status and help determine further steps in care. Radiologists should understand the nuances of axillary management and the scope and challenges of LN marking techniques that significantly increase the precision of limited axillary surgery.
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- 2021
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19. Axillary lymphadenopathy following bivalent COVID-19 booster vaccination
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Elizabeth G. Lane, Kemi Babagbemi, Eralda Mema, and Katerina Dodelzon
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Radiology, Nuclear Medicine and imaging - Published
- 2022
20. Merkel cell carcinoma of the breast: A case report
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Katerina Dodelzon, Eralda Mema, Nishi Mehta, and Paula S. Ginter
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Pathology ,medicine.medical_specialty ,Skin Neoplasms ,medicine.medical_treatment ,Breast Neoplasms ,Vascularity ,Breast cancer ,Biomarkers, Tumor ,medicine ,Humans ,Mammography ,Radiology, Nuclear Medicine and imaging ,Family history ,Aged ,medicine.diagnostic_test ,biology ,Merkel cell carcinoma ,business.industry ,Lumpectomy ,Middle Aged ,medicine.disease ,Carcinoma, Neuroendocrine ,Carcinoma, Merkel Cell ,Synaptophysin ,biology.protein ,Immunohistochemistry ,Female ,medicine.symptom ,business - Abstract
Merkel cell carcinoma (MCC) of the breast is a very rare and aggressive type of neuroendocrine carcinoma of the breast (NECB) that typically occurs in older and immunocompromised individuals often presenting as a large palpable mass (Albright et al., 20181). Imaging features of MCC are similar to other NECBs, typically appearing as an oval circumscribed mass on mammography and as an irregular mass with increased vascularity on sonography (Jeon et al., 20142). While both MCC and primary NECB demonstrate positive immunostaining for synaptophysin, obtaining immunohistochemical stains for specific markers, such as CK7 and CK20 is imperative to confirm the diagnosis of MCC (Albright et al., 20181). We present a case of a 57-year-old female patient with no personal or family history of breast cancer, who presented for evaluation of a palpable abnormality in her left breast. Initial diagnostic mammogram demonstrated a circumscribed mass in the upper outer quadrant of the left breast corresponding to the palpable area of concern, which correlated to an irregular mass with increased vascularity on targeted ultrasound, similar to other NECBs. Pathologic results after tissue sampling yielded poorly differentiated primary NECB. Following neoadjuvant chemotherapy, the patient underwent a lumpectomy and further immunohistochemical stains of the lumpectomy specimen demonstrated diffusely positive synaptophysin, negative CK7, and positive CK20, consistent with MCC of the breast.
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- 2021
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21. National Virtual Visiting Professorship in Breast Imaging
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Katerina Dodelzon, Amy Patel, and Dana Smetherman
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Diagnostic Imaging ,Humans ,Female ,Radiology, Nuclear Medicine and imaging ,Breast - Published
- 2022
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22. Emerging From Behind the Workstation
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Katerina, Dodelzon and Janine T, Katzen
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Radiology, Nuclear Medicine and imaging - Published
- 2022
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23. COVID-19 and Breast Radiologist Wellness: Impact of Gender, Financial Loss, and Childcare Need
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Emily B. Sonnenblick, Basak E. Dogan, Lars J. Grimm, Khai Tran, Brian N. Dontchos, Margarita L. Zuley, Hannah S. Milch, Stamatia Destounis, S. Reed Plimpton, Vandana Dialani, Katerina Dodelzon, and Daniela Markovic
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Adult ,Male ,medicine.medical_specialty ,media_common.quotation_subject ,Anxiety ,Burnout ,Anger ,Logistic regression ,Article ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,Radiologists ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Child ,Pandemics ,Depression (differential diagnoses) ,media_common ,Response rate (survey) ,Finance ,SARS-CoV-2 ,business.industry ,COVID-19 ,Odds ratio ,Middle Aged ,030220 oncology & carcinogenesis ,Respondent ,Female ,Radiology ,medicine.symptom ,business - Abstract
PURPOSE: The purpose of this study was to evaluate the emotional and financial impact of coronavirus disease 2019 (COVID-19) on breast radiologists to understand potential consequences on physician wellness and gender disparities in radiology. METHODS: A 41-question survey was distributed from June to September 2020 to members of the Society of Breast Imaging and the National Consortium of Breast Centers. Psychological distress and financial loss scores were calculated on the basis of survey responses and compared across gender and age subgroups. A multivariate logistic model was used to identify factors associated with psychological distress scores. RESULTS: A total of 628 surveys were completed (18% response rate); the mean respondent age was 52 ± 10 years, and 79% were women. Anxiety was reported by 68% of respondents, followed by sadness (41%), sleep problems (36%), anger (25%), and depression (23%). A higher psychological distress score correlated with female gender (odds ratio [OR], 1.9; P = .001), younger age (OR, 0.8 per SD; P = .005), and a higher financial loss score (OR, 1.4; P < .0001). Participants whose practices had not initiated wellness efforts specific to COVID-19 (54%) had higher psychological distress scores (OR, 1.4; P = .03). Of those with children at home, 38% reported increased childcare needs, higher in women than men (40% versus 29%, P < .001). Thirty-seven percent reported that childcare needs had adversely affected their jobs, which correlated with higher psychological distress scores (OR, 2.2-3.3; P < .05). CONCLUSIONS: Psychological distress was highest among younger and female respondents and those with greater pandemic-specific childcare needs and financial loss. Practice-initiated COVID-19-specific wellness efforts were associated with decreased psychological distress. Policies are needed to mitigate pandemic-specific burnout and worsening gender disparities.
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- 2021
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24. Radial Scars and Complex Sclerosing Lesions of the Breast: Prevalence of Malignancy and Natural History Under Active Surveillance
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Lisa A. Newman, Rache M. Simmons, Jessica Limberg, Jennifer L. Marti, Alexander Swistel, Paula S. Ginter, Elizabeth Kraft, and Katerina Dodelzon
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medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Radial scar ,Breast surgery ,medicine.medical_treatment ,Retrospective cohort study ,Ductal carcinoma ,medicine.disease ,Malignancy ,03 medical and health sciences ,0302 clinical medicine ,Oncology ,030220 oncology & carcinogenesis ,Biopsy ,Atypia ,medicine ,Carcinoma ,030211 gastroenterology & hepatology ,Surgery ,Radiology ,business - Abstract
When needle core biopsies (NCBs) of the breast reveal radial scar or complex sclerosing lesions (RSLs), excision is often recommended despite a low risk of malignancy in the modern era. The optimal management of NCBs revealing RSLs is controversial, and understanding of the natural history of unresected RSLs is limited. We retrospectively analyzed pathology and imaging data from 148 patients with NCB revealing RSL without atypia from 2015 to 2019 to determine the prevalence of malignancy and the behavior of RSLs undergoing active surveillance (AS). The mean age of patients was 52 years, and most lesions were screen-detected (91%). The median lesion size was 6.0 mm (range 2–39). Most patients (66%, n = 98) underwent immediate surgery, while 34% (n = 50) of patients underwent AS, with a median follow-up of 16 months (range 6–51). Of the excised RSLs, 99% (n = 97) were benign and 1% (n = 1) revealed ductal carcinoma in situ (DCIS). In 17% (n = 17) of cases, additional high-risk lesions were discovered upon excision. Among the 50 patients undergoing AS, no lesions progressed on interval imaging. In this cohort, 99% of RSLs undergoing excision were benign, 1% revealed DCIS, and there were no invasive cancers. In the first study of patients with RSLs undergoing AS, we found that all lesions either remained stable or resolved. We propose that the vast majority of patients with RSL on NCB can be safely offered AS, and that routine excision is a low-value intervention.
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- 2021
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25. Unilateral axillary Adenopathy in the setting of COVID-19 vaccine
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Katerina Dodelzon, Rachel Marcus Sales, Kemi Babagbemi, Allison D. Levy, Michele Drotman, Nishi Mehta, and Anika L. McGrath
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medicine.medical_specialty ,COVID-19 Vaccines ,Coronavirus disease 2019 (COVID-19) ,Lymphadenopathy ,Breast malignancy ,030218 nuclear medicine & medical imaging ,Food and drug administration ,03 medical and health sciences ,0302 clinical medicine ,Axillary nodes ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Axillary Adenopathy ,Lymph node ,Unilateral axillary adenopathy ,Vaccines ,business.industry ,SARS-CoV-2 ,Breast Imaging ,COVID-19 ,Vaccination ,medicine.anatomical_structure ,Radiology Nuclear Medicine and imaging ,030220 oncology & carcinogenesis ,Screening ,Radiology ,Differential diagnosis ,business ,Vaccine - Abstract
With the recent U.S. Food and Drug Administration (FDA)-approval and rollout of the Pfizer-BioNTech and Moderna COVID-19 vaccines, it is important for radiologists to consider recent COVID-19 vaccination history as a possible differential diagnosis for patients with unilateral axillary adenopathy. Hyperplastic axillary nodes can be seen on sonography after any vaccination but are more common after a vaccine that evokes a strong immune response, such as the COVID-19 vaccine. As the differential of unilateral axillary adenopathy includes breast malignancy, it is crucial to both thoroughly evaluate the breast for primary malignancy and to elicit history of recent vaccination. As COVID-19 vaccines will soon be available to a larger patient population, radiologists should be familiar with the imaging features of COVID-19 vaccine induced hyperplastic adenopathy and its inclusion in a differential for unilateral axillary adenopathy. Short-term follow-up for unilateral axillary adenopathy in the setting of recent COVID-19 vaccination is an appropriate recommendation, in lieu of immediately performing potentially unnecessary and costly axillary lymph node biopsies., Highlights • Imaging features of new onset unilateral axillary adenopathy in recipients of COVID-19 vaccine are presented • Recognition of recent COVID-19 vaccine status as a cause of unilateral axillary adenopathy is clinically relevant • Short-term follow-up in the setting of unilateral axillary adenopathy and recent COVID-19 vaccine should be considered
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- 2021
26. PET/MRI in breast cancer patients: Added value, barriers to implementation, and solutions
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Katerina Dodelzon, Amy Melsaether, and Geraldine McGinty
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Oncology ,medicine.medical_specialty ,Breast cancer ,business.industry ,Internal medicine ,Added value ,MEDLINE ,Medicine ,Radiology, Nuclear Medicine and imaging ,business ,medicine.disease - Published
- 2020
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27. Lessons learned: A single academic department's unique approach to preventing physician burnout
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Aya Y. Michaels, Katerina Dodelzon, Michele Drotman, and Janine Katzen
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Male ,Physician burnout ,Medical education ,business.industry ,media_common.quotation_subject ,education ,Control (management) ,Flexibility (personality) ,Burnout ,Feeling ,Academic department ,Physicians ,Surveys and Questionnaires ,Depersonalization ,Prevalence ,Humans ,Medicine ,Female ,Radiology, Nuclear Medicine and imaging ,medicine.symptom ,business ,Burnout, Professional ,psychological phenomena and processes ,Autonomy ,media_common - Abstract
Physician burnout is a recognized problem within medicine and its prevalence appears to be increasing. The symptoms include three major components; exhaustion, depersonalization and feeling a lack of accomplishment. The presence of burnout can have major professional and personal consequences. While there has been much commentary on the impact of burnout, little has been published addressing ways to prevent and resolve the issue. Our department has taken a novel and individualized approach to lower burnout. This includes allowing faculty to personalize their schedules as demonstrated by the perspectives of four breast imaging faculty. We as physicians are as diverse as the patient population we treat which needs to be recognized when addressing solutions to burnout. We propose that most practices and departments can find meaningful ways to allow physicians to increase their sense of autonomy through flexibility and control in scheduling. Having leadership open to unique and sometimes unconventional approaches enables a mutually beneficial culture of respect, productivity, and wellness.
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- 2020
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28. Assessing the Positive Predictive Value of Architectural Distortion Detected with Digital Breast Tomosynthesis in BI-RADS 4 Cases
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Janine Katzen, Prapti Y Shingala, Eda Dou, Katerina Dodelzon, and Martha Ksepka
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medicine.medical_specialty ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Cancer ,BI-RADS ,Digital Breast Tomosynthesis ,medicine.disease ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,030220 oncology & carcinogenesis ,Architectural Distortion ,Biopsy ,medicine ,Medical imaging ,Mammography ,Radiology, Nuclear Medicine and imaging ,Radiology ,business - Abstract
Objective The purpose of this study was to evaluate the positive predictive value of biopsy (PPV3) of architectural distortion (AD) detected on digital breast tomosynthesis (DBT) in BI-RADS 4 cases, where suspicion for malignancy remains broad. Methods This Institutional Review Board-approved, retrospective study included screening and diagnostic mammograms performed from August 2015 to December 2017 with DBT and digital mammography (DM) revealing suspicious AD with a BI-RADS 4 assessment. Medical records were reviewed for clinical data, imaging, and pathology results. Malignancy rate was assessed by lesion visibility on DM and DBT. Multivariate analysis was performed to assess the odds ratio (OR) of malignancy. Results A total of 63/179 cases were malignant, yielding a PPV3 of 35%. No significant difference in PPV3 was found by race, personal or family history of breast cancer, presence of microcalcifications, or mammogram type. Architectural distortion was more likely to be malignant when an US correlate was present (PPV3 49% vs 19%; P < 0.0001). Multivariate analysis demonstrated a 3-fold increased OR for malignancy with an US correlate present (P = 0.005). Lesion visibility analysis revealed a higher PPV3 for AD visible on DM-DBT compared with DBT alone (44% vs 26%; P = 0.01) and when an US correlate was present (DM-DBT 54% vs 30%, P = 0.02; DBT-only 43% vs 11%, P < 0.001). Conclusions Tomosynthesis-detected BI-RADS 4 AD are malignant in 35% of cases and are more likely to be malignant if an US correlate is present and if visible on both DM and DBT.
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- 2020
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29. Postoperative Imaging Appearance of an Implantable Three-dimensional Bioabsorbable Tissue Marker After Breast Surgery: Initial Experience at a Single Institution
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Paula S. Ginter, Katerina Dodelzon, Michele Drotman, Elizabeth Kagan Arleo, and Christine Chen
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medicine.medical_specialty ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Breast surgery ,medicine.medical_treatment ,Fibromatosis ,medicine.disease ,Radiation therapy ,Biopsy ,Medical imaging ,Medicine ,Mammography ,Papilloma ,Radiology, Nuclear Medicine and imaging ,Radiology ,business ,Calcification - Abstract
Objective Three-dimensional bioabsorbable tissue marker (BTM) placement during breast surgery is performed for the purpose of improved surgical cavity delineation for radiotherapy and improved cosmetic outcome. The purpose of this study is to evaluate the postsurgical imaging findings of BTM. Methods This Institutional Review Board-approved retrospective review included all patients implanted with BTM at breast surgery from January 2017 to September 2018. Demographics, tumor characteristics, imaging, and histologic findings were evaluated. Medical records were reviewed during a three-year period to evaluate for tumor recurrence. Results Ninety-seven patients had BTM implanted, of which 76 patients had imaging follow-up of at least 1 year. Of the 76 patients who had mammographic follow-up, 3 (3.9%) developed suspicious microcalcifications requiring biopsy, yielding ductal carcinoma in-situ in 2 patients and benign calcifications in 1 patient. Of 61 patients who had sonographic follow-up, 44 (72.1%) patients had complex fluid collections containing avascular, heterogeneously hyperechoic solid components, which remained stable or decreased in size over time; no recurrent tumors were found in this group. One patient (1.6%) had a vascular solid mass, which yielded recurrent papilloma. Four (6.6%) patients developed irregular hypoechoic masses at the surgical site, one of which corresponded with a developing asymmetry mammographically; biopsy yielded fibromatosis. Tissue sampling of the remaining three cases yielded invasive ductal carcinoma, fat necrosis, and radiation changes, respectively. Conclusion Accurate identification of the expected postoperative imaging appearance of BTM may prevent unnecessary biopsy. Suspicious findings necessitating biopsy are pleomorphic calcifications, developing asymmetry and vascular and irregular hypoechoic masses.
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- 2020
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30. Unknown Case: Bilateral Breast Masses in a Male Patient
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Katerina Dodelzon and Joshua Davis
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medicine.medical_specialty ,Radiological and Ultrasound Technology ,Male patient ,business.industry ,Medicine ,Radiology, Nuclear Medicine and imaging ,Radiology ,business - Published
- 2020
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31. Unknown Challenge: Incidental Mass on Screening Ultrasound
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Katerina Dodelzon and Bennett Battle
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medicine.medical_specialty ,Radiological and Ultrasound Technology ,business.industry ,Diabetes mellitus ,Ultrasound ,medicine ,Radiology, Nuclear Medicine and imaging ,Radiology ,Ultrasonography ,business ,medicine.disease - Published
- 2020
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32. Protecting a Gender Diverse Future by Supporting Breastfeeding Radiologists
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Katerina Dodelzon
- Subjects
medicine.medical_specialty ,Breast Feeding ,business.industry ,Family medicine ,Radiologists ,medicine ,Breastfeeding ,Humans ,Female ,Radiology, Nuclear Medicine and imaging ,Health Promotion ,business - Published
- 2022
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33. Evaluation of Palpable Breast Abnormalities
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Janine Katzen and Katerina Dodelzon
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medicine.medical_specialty ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Cancer ,Digital Breast Tomosynthesis ,medicine.disease ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,030220 oncology & carcinogenesis ,Medical imaging ,Medicine ,Mammography ,Radiology, Nuclear Medicine and imaging ,Radiology ,Ultrasonography ,business - Abstract
A palpable breast abnormality is one of the most common presenting clinical breast complaints. Although the majority of palpable abnormalities are benign, they are among the most common presenting symptoms of breast cancer, and those breast cancers detected symptomatically tend to have poorer prognosis than their screen-detected counterparts. Clinical breast examination is a vital part of the workup of palpable abnormalities. However, as physical exam features of most masses are not reliable for categorization of malignancy, imaging evaluation is necessary. Choice of imaging modality, which includes diagnostic mammography and breast ultrasound, is dependent upon patient age. Ultrasound is the primary imaging modality for evaluation of palpable masses in women younger than 30 years of age because of its high negative predictive value and sensitivity and lack of ionizing radiation. For women aged 30–39 years, ultrasound or mammography can be performed as the initial imaging evaluation, with ultrasound maintaining a high sensitivity in women younger than 40 years old. Mammography, often followed by ultrasound, is the recommended imaging evaluation sequence for women aged 40 and older. Utilization of advanced imaging modalities for evaluation of the palpable area of concern is not supported by evidence.
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- 2019
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34. Accuracy of Synthetic 2D Mammography Compared With Conventional 2D Digital Mammography Obtained With 3D Tomosynthesis
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Katerina Dodelzon, Katherine Simon, Janine Katzen, Allison D. Levy, Michele Drotman, Elizabeth Kagan Arleo, and Gulce Askin
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medicine.medical_specialty ,Digital mammography ,medicine.diagnostic_test ,business.industry ,General Medicine ,medicine.disease ,Tomosynthesis ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,030220 oncology & carcinogenesis ,medicine ,Mammography ,Radiology, Nuclear Medicine and imaging ,Medical physics ,business - Abstract
The purpose of this study was to compare the diagnostic performance of synthetic 2D imaging generated from 3D tomosynthesis (DBT) with traditional 2D full-field digital mammography (FFDM) by use of the most up-to-date software algorithm in an urban academic radiology practice.The records of patients undergoing screening mammography with DBT, synthetic 2D imaging, and FFDM between August 13, 2014, and January 31, 2016, were retrospectively collected. The cohort included all biopsy-proven breast cancers detected with screening mammography during the study period (n = 89) and 100 cases of negative or benign (BI-RADS category 1 or 2) findings after 365 days of follow-up. In separate sessions, three readers blinded to outcome reviewed DBT plus synthetic 2D or DBT plus FFDM screening mammograms and assigned a BI-RADS category and probability of malignancy to each case. The diagnostic performance of each modality was assessed by calculating sensitivity and specificity. Reader performance was assessed by ROC analysis to estimate the AUC of the likelihood of malignancy.No statistically significant difference was found in diagnostic accuracy (sensitivity, specificity, positive predictive value, or negative predictive value) between DBT plus synthetic 2D mammography and DBT plus FFDM. There was no statistically significant difference between the AUC of DBT plus synthetic 2D mammography and the AUC of DBT plus FFDM for any reader.DBT plus synthetic 2D mammography performs as well as and not worse than DBT plus FFDM in measures of diagnostic accuracy and may be a viable alternative for decreasing radiation dose without sacrificing diagnostic performance.
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- 2019
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35. Optimizing radiologist productivity and efficiency: Work smarter, not harder
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Anika L, McGrath, Katerina, Dodelzon, Omer A, Awan, Nicholas, Said, and Puneet, Bhargava
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Radiology Information Systems ,Artificial Intelligence ,Radiologists ,Humans ,Radiology, Nuclear Medicine and imaging ,Efficiency ,General Medicine ,Radiology - Abstract
Radiologists' personal productivity and efficiency are critically important for both improving patient outcomes and protecting clinician well-being. There are several solutions that individuals can implement to improve personal productivity and efficiency in the radiology workroom. Strategies include understanding the psychology behind productivity, using personal productivity methodologies to accomplish daily tasks, and learning to modulate stress to optimize performance. Institutional infrastructure requirements include a robust departmental commitment to information technology and informatics, including universal log-in systems, internal websites, and dashboards. The workstation itself can be optimized by utilizing hanging protocols, customized keyboard shortcuts, hotkeys, advanced scripts, gaming mice, and other input devices. Personal devices like smartphones can be harnessed to maximize productivity by using online storage applications and radiology-specific applications to augment knowledge. Reading room layouts must be designed to minimize interruptions and workstations must consider ergonomics to prevent fatigue and strain. High-efficiency teams also need to be created to allow radiologists to delegate non-clinical tasks to reduce administrative burdens. Lastly, continued advances in artificial intelligence including the use of smart report templates will lead to substantial gains in radiologists' productivity and efficiency.
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- 2022
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36. Breast Imaging for Transgender Individuals: Assessment of Current Practice and Needs
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Emily B. Sonnenblick, Lizza Lebron-Zapata, Roger Yang, Katerina Dodelzon, Varadan Sevilimedu, Hannah Milch, Vandana Dialani, Brian N. Dontchos, Stamatia Destounis, and Lars Grimm
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Male ,Sexual and Gender Minorities ,Gender Identity ,Humans ,Radiology, Nuclear Medicine and imaging ,Breast Neoplasms ,Female ,Transgender Persons ,Early Detection of Cancer ,United States ,Mammography - Abstract
The aim of this study was to investigate breast radiologists' practices related to recording sex and gender in the electronic medical record, knowledge and attitudes about breast cancer screening recommendations for transgender individuals, and experience and willingness to enter screening mammography data from transgender patients into databases that document service provision and outcomes of cancer detection protocols.A 19-question anonymous survey was distributed by e-mail to all active physician members of the Society of Breast Imaging. Response characteristics were assessed as frequencies and percentages and compared between groups using the Fisher exact test or χFour hundred one radiologists across the United States and Canada responded (response rate 18%). Recording birth-assigned sex distinct from gender identity was reported by 44 of 352 respondents (13%). Depending on geographic region, 38% to 62% of breast radiologists followed screening guidelines for transgender women, and 226 of 349 (65%) did not provide screening recommendations for transgender men. Of 400, 324 (81%) believed that the evidence base for screening transgender individuals is incomplete, and 247 of 352 (70%) were either unsure of or had no Lesbian, Gay, Bisexual, Transgender, Queer competency training. A majority (247 of 401 [62%]) of respondents reported that they would enroll transgender patients in existing or novel national databases.In the practice of breast imaging, there is a substantial need to record transgender and other gender-nonconforming information. Breast radiologists differ in their practice and knowledge regarding screening of transgender women and men but expressed interest in contributing data to facilitate longitudinal databases needed to inform cancer screening guidelines.
- Published
- 2021
37. Does prioritizing patient safety during the COVID-19 pandemic come at the expense of patient satisfaction?
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Kathryn E. Dean, Katerina Dodelzon, and Hung Lin
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2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Breast Imaging ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,MEDLINE ,medicine.disease ,Patient safety ,Patient satisfaction ,Radiology Nuclear Medicine and imaging ,Pandemic ,medicine ,Radiology, Nuclear Medicine and imaging ,Medical emergency ,business - Abstract
Highlights • Patient safety measures did not come at the expense of patient satisfaction, and rather may even improve it. • Reducing wait time in the waiting area can improve patient experience and minimize patient-to-patient exposure. • Text messaging to alert patient any scheduling change could be employed to avoid waiting room crowding. • Extending facility hours with staff working in shifts could also be considered to add flexibility to patient appointments. • The challenge posed by the COVID-19 pandemic gives us an opportunity to improve on the old practice model.
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- 2021
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38. Increasing Imaging Value to Breast Cancer Care Through Prognostic Modeling of Multiparametric MRI Features in Patients Undergoing Neoadjuvant Chemotherapy
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Katerina Dodelzon
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Humans ,Breast Neoplasms ,Female ,Radiology, Nuclear Medicine and imaging ,Breast ,Multiparametric Magnetic Resonance Imaging ,Prognosis ,Neoadjuvant Therapy - Published
- 2022
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39. High-Risk Lesions Detected by MRI-Guided Core Biopsy: Upgrade Rates at Surgical Excision and Implications for Management
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Matthew R. Naunheim, Paula S. Ginter, Genevieve N. Abbey, Katerina Dodelzon, and Aya Y. Michaels
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Adult ,Image-Guided Biopsy ,medicine.medical_specialty ,Radial scar ,Lobular carcinoma ,Mucocele ,Breast Neoplasms ,Malignancy ,Magnetic Resonance Imaging, Interventional ,030218 nuclear medicine & medical imaging ,Papilloma, Intraductal ,03 medical and health sciences ,Cicatrix ,0302 clinical medicine ,Biopsy ,medicine ,Carcinoma ,Breast MRI ,Humans ,Radiology, Nuclear Medicine and imaging ,Breast ,Aged ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,General Medicine ,Ductal carcinoma ,Middle Aged ,medicine.disease ,Carcinoma, Intraductal, Noninfiltrating ,030220 oncology & carcinogenesis ,Papilloma ,Female ,Radiology ,Breast Carcinoma In Situ ,business ,Precancerous Conditions - Abstract
OBJECTIVE. The purpose of our study was to evaluate the upgrade rates of high-risk lesions (HRLs) diagnosed by MRI-guided core biopsy and to assess which clinical and imaging characteristics are predictive of upgrade to malignancy. MATERIALS AND METHODS. A retrospective review was performed of all women who presented to an academic breast radiology center for MRI-guided biopsy between January 1, 2015, and November 30, 2018. Histopathologic results from each biopsy were extracted. HRLs-that is, atypical ductal hyperplasia (ADH), lobular carcinoma in situ (LCIS), atypical lobular hyperplasia (ALH), radial scar, papilloma, flat epithelial atypia (FEA), benign vascular lesion (BVL), and mucocelelike lesion-were included for analysis. Clinical history, imaging characteristics, surgical outcome, and follow-up data were recorded. Radiologic-pathologic correlation was performed. RESULTS. Of 810 MRI-guided biopsies, 189 cases (23.3%) met the inclusion criteria for HRLs. Of the 189 HRLs, 30 cases were excluded for the following reasons: 15 cases were lost to follow-up, six cases were in patients who received neoadjuvant chemotherapy after biopsy, two lesions that were not excised had less than 2 years of imaging follow-up, and seven lesions had radiologic-pathologic discordance at retrospective review. Of the 159 HRLs in our study cohort, 13 (8.2%) were upgraded to carcinoma. Surgical upgrade rates were high for ADH (22.5%, 9/40) and FEA (33.3%, 1/3); moderate for LCIS (6.3%, 3/48); and low for ALH (0.0%, 0/11), radial scar (0.0%, 0/28), papilloma (0.0%, 0/26), and BVL (0.0%, 0/3). Of the upgraded lesions, 69.2% (9/13) were upgraded to ductal carcinoma in situ (DCIS) or well-differentiated carcinoma. ADH lesions were significantly more likely to be upgraded than non-ADH lesions (p = .005). CONCLUSION. ADH diagnosed by MRI-guided core biopsy warrants surgical excision. The other HRLs, however, may be candidates for imaging follow-up rather than excision, especially after meticulous radiologic-pathologic correlation.
- Published
- 2021
40. Impact of COVID-19 on Breast Imaging Practice Operations and Recovery Efforts: A North American Study
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Basak E. Dogan, M D Stamatia Destounis, Emily B. Sonnenblick, Brian N. Dontchos, Margarita L. Zuley, Khai Tran, Vandana Dialani, Hannah S. Milch, Katerina Dodelzon, and Lars J. Grimm
- Subjects
Oncology ,2019-20 coronavirus outbreak ,medicine.medical_specialty ,Coronavirus disease 2019 (COVID-19) ,Breast imaging ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,operations ,030218 nuclear medicine & medical imaging ,Breast neoplasm screening ,03 medical and health sciences ,recovery ,0302 clinical medicine ,Internal medicine ,Biopsy ,Medicine ,Radiology, Nuclear Medicine and imaging ,Geographic difference ,Original Research ,medicine.diagnostic_test ,Radiological and Ultrasound Technology ,business.industry ,breast imaging ,screening ,AcademicSubjects/MED00620 ,COVID-19 ,Editor's Choice ,Radiology Nuclear Medicine and imaging ,030220 oncology & carcinogenesis ,diagnostic breast imaging ,AcademicSubjects/MED00870 ,business - Abstract
Objective To assess the impact of the COVID-19 pandemic on breast imaging facilities’ operations and recovery efforts across North America. Methods A survey on breast imaging facilities’ operations and strategies for recovery during the COVID-19 pandemic was distributed to the membership of the Society of Breast Imaging and National Consortium of Breast Centers from June 4, 2020, to July 14, 2020. A descriptive summary of responses was performed. Comparisons were made between demographic variables of respondents and questions of interest using a Pearson chi-square test. Results There were 473 survey respondents (response rate of 13%). The majority of respondents (70%; 332/473) reported 80%–100% breast imaging volume reduction, with 94% (447/473) reporting postponement of screening mammography. The majority of respondents (97%; 457/473) continued to perform biopsies. There were regional differences in safety measures taken for staff (P = 0.004), with practices in the West more likely reporting no changes in the work environment compared to other regions. The most common changes to patients’ experience included spacing out of furniture in waiting rooms (94%; 445/473), limiting visitors (91%; 430/473), and spacing out appointments (83%). A significantly higher proportion of practices in the Northeast (95%; 104/109) initiated patient scheduling changes compared to other regions (P = 0.004). Conclusion COVID-19 had an acute impact on breast imaging facilities. Although common national operational patterns emerged, geographic variability was notable in particular in recovery efforts. These findings may inform future best practices for delivering breast imaging care amid the ongoing and geographically shifting COVID-19 pandemic.
- Published
- 2021
41. The importance of imaging – Perspectives from redeployment
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Juliana Atallah, Andrew D. Schweitzer, Dennis Toy, Shreena Shah, and Katerina Dodelzon
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Clinical team ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,Patient care ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Nursing ,Pandemic ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Pandemics ,Practice, Policy & Education ,business.industry ,COVID-19 ,United States ,Redeployment ,Active participation ,Radiology Nuclear Medicine and imaging ,030220 oncology & carcinogenesis ,Workforce ,Radiology ,business ,Healthcare system - Abstract
As the coronavirus disease 2019 (COVID-19) pandemic strains the healthcare system, radiology residents across the United States have become a vital part of the redeployed workforce. Through a series of four cases of COVID-19 patients encountered on the wards, we highlight the insight and unique set of skills redeployed radiology residents possess that are essential to patient care during this crisis. By increasing visibility through active participation on the clinical team, we demonstrate the fundamental role radiology has in the greater field of medicine., Highlights • Radiology residents are an asset to the redeployed workforce and have meaningful contribution to patient care. • Dynamic imaging rounds became critical in clinical decision-making and expediting appropriate management. • Redeployment increases the visibility of radiology and highlights the essential role of the radiologist.
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- 2021
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42. The Design and Preliminary Experience with a Virtual Diversity Visiting Student Acting Internship in Radiology for Underrepresented Minority Medical Students
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Robert J. Min, Geraldine McGinty, Katerina Dodelzon, Alan C. Legasto, Andrew D. Schweitzer, Kemi Babagbemi, Stephanie Spottswood, Lily M. Belfi, and Nicole Lamparello
- Subjects
medicine.medical_specialty ,Students, Medical ,media_common.quotation_subject ,education ,ComputingMethodologies_IMAGEPROCESSINGANDCOMPUTERVISION ,Specialty ,computer.software_genre ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Videoconferencing ,Internship ,Underrepresented Minority ,ComputingMilieux_COMPUTERSANDEDUCATION ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Curriculum ,Pandemics ,Minority Groups ,media_common ,ComputingMilieux_THECOMPUTINGPROFESSION ,Virtual Reality ,COVID-19 ,Internship and Residency ,Cultural Diversity ,030220 oncology & carcinogenesis ,Aptitude ,Professional association ,Radiology ,Psychology ,computer ,Diversity (politics) - Abstract
Objective Benefits of a diverse physician workforce are numerous and the impact of a lack of diversity has been highlighted with the COVID-19 pandemic. Despite the commitment of professional societies such as the American College of Radiology to diversity in Radiology, the field and its residency training programs remain the least diverse. With COVID-19 related suspension of in-person medical student rotations, our Department of Radiology redesigned and implemented a virtual radiology internship for underrepresented minority (URM) medical students. Methods A four-week virtual radiology internship was designed to provide clinical exposure to radiology and to allow students to gain an understanding of what a career in radiology entails. Course design included videoconference patient care sessions, didactic lectures, online modules, mentoring, and extra-clinical curriculum. Feedback from students was collected using online surveys assessing pre- and postcourse attitudes and understanding of a career in radiology and the students’ perceived aptitude for such a career, as well as course component evaluation. Results Three participants were enrolled in the inaugural clerkship. All noted exceptional educational course content and ample opportunities to build connections with faculty and residents—with mentoring seen as the highlight of the course. All indicated a significant shift in perception of the field and in declaring interest in pursuing a career in radiology. Conclusion Virtual radiology internship for URM students is a feasible paradigm to address potential impediments to diversification of the specialty by both engaging interested URM medical students in a career in radiology and arming them with the tools for a successful application to radiology residency.
- Published
- 2020
43. Radial Scars and Complex Sclerosing Lesions of the Breast: Prevalence of Malignancy and Natural History Under Active Surveillance
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Elizabeth, Kraft, Jessica N, Limberg, Katerina, Dodelzon, Lisa A, Newman, Rache, Simmons, Alexander, Swistel, Paula S, Ginter, and Jennifer L, Marti
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Cicatrix ,Carcinoma, Intraductal, Noninfiltrating ,Prevalence ,Humans ,Breast Neoplasms ,Female ,Biopsy, Large-Core Needle ,Breast ,Middle Aged ,Watchful Waiting ,Mammography ,Retrospective Studies - Abstract
When needle core biopsies (NCBs) of the breast reveal radial scar or complex sclerosing lesions (RSLs), excision is often recommended despite a low risk of malignancy in the modern era. The optimal management of NCBs revealing RSLs is controversial, and understanding of the natural history of unresected RSLs is limited.We retrospectively analyzed pathology and imaging data from 148 patients with NCB revealing RSL without atypia from 2015 to 2019 to determine the prevalence of malignancy and the behavior of RSLs undergoing active surveillance (AS).The mean age of patients was 52 years, and most lesions were screen-detected (91%). The median lesion size was 6.0 mm (range 2-39). Most patients (66%, n = 98) underwent immediate surgery, while 34% (n = 50) of patients underwent AS, with a median follow-up of 16 months (range 6-51). Of the excised RSLs, 99% (n = 97) were benign and 1% (n = 1) revealed ductal carcinoma in situ (DCIS). In 17% (n = 17) of cases, additional high-risk lesions were discovered upon excision. Among the 50 patients undergoing AS, no lesions progressed on interval imaging.In this cohort, 99% of RSLs undergoing excision were benign, 1% revealed DCIS, and there were no invasive cancers. In the first study of patients with RSLs undergoing AS, we found that all lesions either remained stable or resolved. We propose that the vast majority of patients with RSL on NCB can be safely offered AS, and that routine excision is a low-value intervention.
- Published
- 2020
44. Breast cancer in women under age 40: A decade of trend analysis at a single institution
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Gulce Askin, Connie Moying Lu, Esther Cheng, Anna Starikov, Charlene Thomas, Melissa Reichman, Anthony Blackburn, Katerina Dodelzon, Julie Kim, Elizabeth Kagan Arleo, Arpita Bose, and Elizabeth Reznik
- Subjects
Adult ,medicine.medical_specialty ,Population ,Breast Neoplasms ,Disease ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Breast cancer ,Medicine ,Humans ,Mass Screening ,Radiology, Nuclear Medicine and imaging ,Stage (cooking) ,education ,Neoplasm Staging ,Retrospective Studies ,education.field_of_study ,business.industry ,Obstetrics ,Incidence (epidemiology) ,Public health ,Retrospective cohort study ,medicine.disease ,Trend analysis ,030220 oncology & carcinogenesis ,Female ,Morbidity ,business ,Mammography - Abstract
Background Women should be evaluated for breast cancer risk by age 30 to assess for screening need. Recent trends in breast cancer in this population may further inform recommendations. Objective The aim of this study was to analyze trends over time in the rate of breast cancer, tumor characteristics and treatment in women under age 40. Methods Retrospective cohort study of women under age 40 at our institution diagnosed with breast cancer from January 2007 to April 2018 was conducted. Patient demographics, tumor characteristics and treatment outcomes were collected. Descriptive statistics and the Mann-Kendell Trend test were calculated. Two-proportion z-tests were used to compare proportions of stage, pathology and treatment between 2007-2013 and 2014–2018. Results 197 women under age 40 were treated for a new diagnosis of breast cancer at our institution. A higher proportion of women were diagnosed with invasive carcinoma in 2013–2018 (91%) compared to 2007–2012 (78%), p = 0.008. A higher proportion of women were diagnosed with advanced stage disease (stage III-IV) in 2013–2018 (24%) compared to 2007–2012 (2%), p = 0.001. No statistically significant evidence for an increasing trend of overall rate of breast cancer over the last 11 years (p = 0.419) was observed. Conclusions While no statistically significant increase in overall rate of breast cancer was noted, an increase in invasive and later staged breast cancers was observed. Clinical impact Rise in more aggressive cancers in a population that is largely not screened may have implications both on the individual young woman's morbidity as well as on a public health level.
- Published
- 2020
45. Bleeding risk after percutaneous breast needle biopsy in patients on anticoagulation therapy
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Melissa Reichman, Paige McMahon, and Katerina Dodelzon
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Image-Guided Biopsy ,medicine.medical_specialty ,Percutaneous ,Standard of care ,Breast needle biopsy ,Breast imaging ,Breast Neoplasms ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Hematoma ,Biopsy ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,In patient ,Breast ,Retrospective Studies ,medicine.diagnostic_test ,business.industry ,General surgery ,Biopsy, Needle ,Anticoagulants ,medicine.disease ,030220 oncology & carcinogenesis ,Tissue diagnosis ,Biopsy, Large-Core Needle ,business - Abstract
Image-guided core needle biopsy (CNB) is the standard of care procedure for tissue diagnosis of suspicious breast lesions. While complications are exceedingly rare, the most common complications include bleeding and hematoma formation. With an increasing number of patients on anticoagulation therapy (AT), it is important to determine whether continuation of these medications during CNB increases bleeding risk. While previous studies have demonstrated the safety in continuation of AT during CNB, American College of Radiology (ACR) guidelines recommend practitioners decide whether cessation is necessary on a case-by-case basis as this may put patients at risk for thromboembolic events. The purpose of this review is to analyze the literature on anticoagulation and bleeding risk during CNB to guide clinical practice.
- Published
- 2020
46. Supporting a Work-Life Balance for Radiology Resident Parents
- Author
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Andrew D. Schweitzer, Shreena Shah, and Katerina Dodelzon
- Subjects
Parents ,2019-20 coronavirus outbreak ,Coronavirus disease 2019 (COVID-19) ,business.industry ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,Work–life balance ,Work-Life Balance ,MEDLINE ,Internship and Residency ,medicine.disease ,Article ,Radiography ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Medical emergency ,business ,Radiology - Published
- 2020
47. Performance of 2D Synthetic Mammography Versus Digital Mammography in the Detection of Microcalcifications at Screening
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Katherine Simon, Aya Y. Michaels, Eda Dou, Janine Katzen, Katerina Dodelzon, Allison D. Levy, and Gulce Askin
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Adult ,medicine.medical_specialty ,Digital mammography ,Breast Neoplasms ,030218 nuclear medicine & medical imaging ,Diagnosis, Differential ,03 medical and health sciences ,Breast Diseases ,0302 clinical medicine ,medicine ,Mammography ,Humans ,Radiology, Nuclear Medicine and imaging ,Medical physics ,Aged ,Retrospective Studies ,Aged, 80 and over ,medicine.diagnostic_test ,business.industry ,Calcinosis ,General Medicine ,Digital Breast Tomosynthesis ,Middle Aged ,Full field digital mammography ,030220 oncology & carcinogenesis ,Female ,business - Abstract
OBJECTIVE. The purpose of this study is to compare the performance of 2D synthetic mammography (SM) to that of full-field digital mammography (FFDM) in the detection of microcalcifications and to e...
- Published
- 2020
48. Paid family leave in a large urban center academic radiology department: How we do it
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Katerina Dodelzon and Andrew D. Schweitzer
- Subjects
medicine.medical_specialty ,business.industry ,Family medicine ,Medicine ,Radiology, Nuclear Medicine and imaging ,Center (algebra and category theory) ,business ,Family Leave - Published
- 2020
49. Effect of a communication lecture tutorial on breast imaging trainees' confidence with challenging breast imaging patient interactions
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Katerina Dodelzon, Janine Katzen, Melissa Reichman, and Gulce Askin
- Subjects
medicine.medical_specialty ,Breast imaging ,education ,Truth Disclosure ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Surveys and Questionnaires ,ComputingMilieux_COMPUTERSANDEDUCATION ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,In patient ,Medical physics ,Breast ,Fellowships and Scholarships ,Pre and post ,Curriculum ,Physician-Patient Relations ,business.industry ,Communication ,Future career ,Skill development ,030220 oncology & carcinogenesis ,Female ,Clinical Competence ,Communication skills ,business ,Radiology ,Limited resources - Abstract
Purpose The aim of the study was to evaluate the effect of a one-hour lecture based communication curriculum on breast imaging trainees' confidence in communicating with patients in a challenging communication setting such as delivering bad news or radiologic error disclosure. Methods 12 breast imaging trainees from an academic fellowship program completed questionnaires before and after a communication tutorial. A four breast imaging specific scenario questionnaire assessed confidence by asking the trainees to rank agreement with statements related to their attitude in those specific settings. 12-month follow-up questionnaire was sent to the graduating fellows assessing their -overall confidence in patient communication, the contribution of the curriculum to their self-perceived communication skill and their likelihood in disclosing a radiologic error to a patient. Results All trainees completed the pre and post lecture questionnaire. After the communication tutorial, all trainees reported increased confidence in communicating with patients in a variety of challenging settings with pre lecture survey mean confidence score of 38/98 and post lecture survey mean score of 85.3/98, P = 0.003. Three of eight trainees who completed the 12-month follow up questionnaire reported confidence in their communication skills and reported that the tutorial significantly contributed to their communication skill development. All three agreed that they would be likely to disclose a medical error should they encounter it in their future career. Conclusions A limited resource one-hour lecture communication tutorial provides effective communication training for breast imaging fellows and is a promising part of a breast imaging curriculum.
- Published
- 2020
50. Virtual wins
- Author
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Katerina, Dodelzon and Elizabeth, Arleo
- Subjects
Radiology Nuclear Medicine and imaging ,Radiology, Nuclear Medicine and imaging - Published
- 2021
- Full Text
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