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1. Associations Of Personality Traits With The Capacity-Performance Discrepancy Of Functional Outcome In Patients With Schizophrenia

Author

Uchino T, Nemoto T, Yamaguchi T, Katagiri N, Tsujino N, Murakami Y, Tanaka K, and Mizuno M

Subjects
Functional capacity, Performance-based assessment, Real-world functioning, Social functioning, Temperament and Character Inventory, Neurosciences. Biological psychiatry. Neuropsychiatry, RC321-571, Neurology. Diseases of the nervous system, RC346-429
Abstract

Takashi Uchino,1,2 Takahiro Nemoto,1 Taiju Yamaguchi,1 Naoyuki Katagiri,1 Naohisa Tsujino,1 Yoshitaka Murakami,3 Kuniaki Tanaka,2 Masafumi Mizuno1 1Department of Neuropsychiatry, Toho University Graduate School of Medicine, Tokyo 143-8540, Japan; 2Tokyo Adachi Hospital, Tokyo 121-0064, Japan; 3Department of Medical Statistics, Toho University School of Medicine, Tokyo 143-8540, JapanCorrespondence: Takahiro NemotoDepartment of Neuropsychiatry, Toho University Graduate School of Medicine, 5-21-16 Omori-Nishi, Ota-ku, Tokyo 143-8540, JapanTel +81 3 37624151Fax +81 3 54715774Email takahiro.nemoto@med.toho-u.ac.jpObjective: Functional capacity, which indicates one’s ability to perform everyday living tasks, contributes to real-world functional performance in patients with schizophrenia. However, functional capacity is sometimes not comparable with functional performance in clinical settings. We hypothesized that specific personality traits are related to this capacity-performance discrepancy of functional outcome.Methods: The measures in this study were the UCSD Performance-based Skills Assessment Brief (UPSA-B) for functional capacity, the Social Functioning Scale (SFS) for functional performance, and the Temperament and Character Inventory-140 (TCI-140) for personality traits. A total of 94 stable outpatients with schizophrenia were divided into four groups based on combinations of their UPSA-B and SFS cut-off points, as follows: a high capacity and high performance (HH) group, a high capacity but low performance (HL) group, a low capacity but high performance (LH) group, and a low capacity and low performance (LL) group.Results: There were no significant differences in demographics among the four groups. The LH group showed a significantly lower harm avoidance level than the LL group. The HL group showed a significantly lower persistence level than the HH group.Conclusion: Lower harm avoidance may enhance functional performance, and lower persistence can limit functional performance, regardless of the primary levels of functional capacity in patients with schizophrenia. Novel and individualized psychosocial treatments considering the individual’s personality traits seem to be helpful for maximizing their functional performance in the community.Keywords: functional capacity, performance-based assessment, real-world functioning, social functioning, Temperament and Character Inventory

Published
2019

3. PB1316 Impact of Synonymous Gene Recoding on ADAMTS13

Author

Lin, B., primary, Amarasinghe, R., additional, Katneni, U., additional, Jankowska, K., additional, Hamasaki-Katagiri, N., additional, Holcomb, D., additional, Padhiar, N., additional, Fumagalli, S., additional, Phue, J., additional, Wu, W., additional, Ghosh, A., additional, Freedberg, D., additional, Kimchi, O., additional, Shen, R., additional, Komar, A., additional, Sauna, Z., additional, and Kimchi-Sarfaty, C., additional

Published
2023
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4. $\pi$NN coupling and two-pion photoproduction on the nucleon

Author

Hirata, M., Katagiri, N., and Takaki, T.

Subjects
Nuclear Theory
Abstract

Effects of non-resonant photoproductions arising from two different $\pi NN$ couplings are investigated in the $\gamma N\to\pi\pi N$ reaction. We find that the pseudoscalar (PS) $\pi NN$ coupling is generally preferable to the pseudovector (PV) $\pi NN$ coupling and particularly the total cross sections are successfully described by the model with the PS $\pi NN$ coupling. In order to see the difference between the two couplings, we also show the results of invariant mass spectra and helicity-dependent cross sections in various isospin channels calculated with the PS and PV couplings., Comment: 35 pages, 11 figures, minor changes and version to be published in Phys.Rev.C

Published
2002
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5. Nuclear Photoabsorption at Photon Energies between 300 and 850 Mev

Author

Hirata, M., Katagiri, N., Ochi, K., and Takaki, T.

Subjects
Nuclear Theory
Abstract

We construct the formula for the photonuclear total absorption cross section using the projection method and the unitarity relation. Our treatment is very effective when interference effects in the absorption processes on a nucleon are strong. The disappearance of the peak around the position of the $D_{13}$ resonance in the nuclear photoabsorption can be explained with the cooperative effect of the interference in two-pion production processes,the Fermi motion, the collision broadenings of $\Delta$ and $N^*$, and the pion distortion in the nuclear medium. The change of the interference effect by the medium plays an important role., Comment: 22pages,7figures,revtex4

Published
2001
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6. Neuroanatomical heterogeneity and homogeneity in individuals at clinical high risk for psychosis

Author

Baldwin, H, Radua, J, Antoniades, M, Haas, SS, Frangou, S, Agartz, I, Allen, P, Andreassen, OA, Atkinson, K, Bachman, P, Baeza, I, Bartholomeusz, CF, Chee, MWL, Colibazzi, T, Cooper, RE, Corcoran, CM, Cropley, VL, Ebdrup, BH, Fortea, A, Glenthoj, LB, Hamilton, HK, Haut, KM, Hayes, RA, He, Y, Heekeren, K, Kaess, M, Kasai, K, Katagiri, N, Kim, M, Kindler, J, Klaunig, MJ, Koike, S, Koppel, A, Kristensen, TD, Bin Kwak, Y, Kwon, JS, Lawrie, SM, Lebedeva, I, Lee, J, Lin, A, Loewy, RL, Mathalon, DH, Michel, C, Mizrahi, R, Moller, P, Nelson, B, Nemoto, T, Nordholm, D, Omelchenko, MA, Pantelis, C, Raghava, JM, Rossberg, J, Roessler, W, Salisbury, DF, Sasabayashi, D, Schall, U, Smigielski, L, Sugranyes, G, Suzuki, M, Takahashi, T, Tamnes, CK, Tang, J, Theodoridou, A, Thomopoulos, S, Tomyshev, AS, Uhlhaas, PJ, Vaernes, TG, van Amelsvoort, TAMJ, Van Erp, TGM, Waltz, JA, Westlye, LT, Wood, SJ, Zhou, JH, McGuire, P, Thompson, PM, Jalbrzikowski, M, Hernaus, D, Fusar-Poli, P, Baldwin, H, Radua, J, Antoniades, M, Haas, SS, Frangou, S, Agartz, I, Allen, P, Andreassen, OA, Atkinson, K, Bachman, P, Baeza, I, Bartholomeusz, CF, Chee, MWL, Colibazzi, T, Cooper, RE, Corcoran, CM, Cropley, VL, Ebdrup, BH, Fortea, A, Glenthoj, LB, Hamilton, HK, Haut, KM, Hayes, RA, He, Y, Heekeren, K, Kaess, M, Kasai, K, Katagiri, N, Kim, M, Kindler, J, Klaunig, MJ, Koike, S, Koppel, A, Kristensen, TD, Bin Kwak, Y, Kwon, JS, Lawrie, SM, Lebedeva, I, Lee, J, Lin, A, Loewy, RL, Mathalon, DH, Michel, C, Mizrahi, R, Moller, P, Nelson, B, Nemoto, T, Nordholm, D, Omelchenko, MA, Pantelis, C, Raghava, JM, Rossberg, J, Roessler, W, Salisbury, DF, Sasabayashi, D, Schall, U, Smigielski, L, Sugranyes, G, Suzuki, M, Takahashi, T, Tamnes, CK, Tang, J, Theodoridou, A, Thomopoulos, S, Tomyshev, AS, Uhlhaas, PJ, Vaernes, TG, van Amelsvoort, TAMJ, Van Erp, TGM, Waltz, JA, Westlye, LT, Wood, SJ, Zhou, JH, McGuire, P, Thompson, PM, Jalbrzikowski, M, Hernaus, D, and Fusar-Poli, P

Abstract

Individuals at Clinical High Risk for Psychosis (CHR-P) demonstrate heterogeneity in clinical profiles and outcome features. However, the extent of neuroanatomical heterogeneity in the CHR-P state is largely undetermined. We aimed to quantify the neuroanatomical heterogeneity in structural magnetic resonance imaging measures of cortical surface area (SA), cortical thickness (CT), subcortical volume (SV), and intracranial volume (ICV) in CHR-P individuals compared with healthy controls (HC), and in relation to subsequent transition to a first episode of psychosis. The ENIGMA CHR-P consortium applied a harmonised analysis to neuroimaging data across 29 international sites, including 1579 CHR-P individuals and 1243 HC, offering the largest pooled CHR-P neuroimaging dataset to date. Regional heterogeneity was indexed with the Variability Ratio (VR) and Coefficient of Variation (CV) ratio applied at the group level. Personalised estimates of heterogeneity of SA, CT and SV brain profiles were indexed with the novel Person-Based Similarity Index (PBSI), with two complementary applications. First, to assess the extent of within-diagnosis similarity or divergence of neuroanatomical profiles between individuals. Second, using a normative modelling approach, to assess the 'normativeness' of neuroanatomical profiles in individuals at CHR-P. CHR-P individuals demonstrated no greater regional heterogeneity after applying FDR corrections. However, PBSI scores indicated significantly greater neuroanatomical divergence in global SA, CT and SV profiles in CHR-P individuals compared with HC. Normative PBSI analysis identified 11 CHR-P individuals (0.70%) with marked deviation (>1.5 SD) in SA, 118 (7.47%) in CT and 161 (10.20%) in SV. Psychosis transition was not significantly associated with any measure of heterogeneity. Overall, our examination of neuroanatomical heterogeneity within the CHR-P state indicated greater divergence in neuroanatomical profiles at an individual level, irre

Published
2022

10. Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis

Author

ENIGMA Clinical High Risk for Psychosis Working Group, Jalbrzikowski M, Hayes RA, Wood SJ, Nordholm D, Zhou JH, Fusar-Poli P, Uhlhaas PJ, Takahashi T, Sugranyes G, Kwak YB, Mathalon DH, Katagiri N, Hooker CI, Smigielski L, Colibazzi T, Esther Via Virgili, Tang J, Koike S, Rasser PE, Michel C, Lebedeva I, Hegelstad WTV, de la Fuente-Sandoval C, Waltz JA, Mizrahi R, Corcoran CM, Resch F, Tamnes CK, Haas SS, Lemmers-Jansen ILJ, Agartz I, Allen P, Amminger GP, Andreassen OA, Atkinson K, Bachman P, Baeza I, Baldwin H, Bartholomeusz CF, Borgwardt S, Catalano S, Chee MWL, Chen X, Cho KIK, Cooper RE, Cropley VL, Dolz M, Ebdrup BH, Fortea A, Glenthøj LB, Glenthøj BY, de Haan L, Hamilton HK, Harris MA, Haut KM, He Y, Heekeren K, Heinz A, Hubl D, Hwang WJ, Kaess M, Kasai K, Kim M, Kindler J, Klaunig MJ, Koppel A, Kristensen TD, Kwon JS, Lawrie SM, Lee J, León-Ortiz P, Lin A, Loewy RL, Ma X, McGorry P, McGuire P, Mizuno M, Møller P, Moncada-Habib T, Muñoz Samons D, Nelson B, Nemoto T, Nordentoft M, Omelchenko MA, Oppedal K, Ouyang L, Pantelis C, Pariente JC, Raghava JM, Reyes-Madrigal F, Roach BJ, Røssberg JI, Rössler W, Salisbury DF, Sasabayashi D, Schall U, Schiffman J, Schlagenhauf F, Schmidt A, Sørensen ME, Suzuki M, Theodoridou A, Tomyshev AS, Tor J, Værnes TG, Velakoulis D, Venegoni GD, Vinogradov S, Wenneberg C, Westlye LT, Yamasue H, Yuan L, Yung AR, van Amelsvoort TAMJ, Turner JA, van Erp TGM, Thompson PM, and Hernaus D

Abstract

IMPORTANCE: The ENIGMA clinical high risk (CHR) for psychosis initiative, the largest pooled neuroimaging sample of individuals at CHR to date, aims to discover robust neurobiological markers of psychosis risk. OBJECTIVE: To investigate baseline structural neuroimaging differences between individuals at CHR and healthy controls as well as between participants at CHR who later developed a psychotic disorder (CHR-PS+) and those who did not (CHR-PS-). DESIGN, SETTING, AND PARTICIPANTS: In this case-control study, baseline T1-weighted magnetic resonance imaging (MRI) data were pooled from 31 international sites participating in the ENIGMA Clinical High Risk for Psychosis Working Group. CHR status was assessed using the Comprehensive Assessment of At-Risk Mental States or Structured Interview for Prodromal Syndromes. MRI scans were processed using harmonized protocols and analyzed within a mega-analysis and meta-analysis framework from January to October 2020. MAIN OUTCOMES AND MEASURES: Measures of regional cortical thickness (CT), surface area, and subcortical volumes were extracted from T1-weighted MRI scans. Independent variables were group (CHR group vs control group) and conversion status (CHR-PS+ group vs CHR-PS- group vs control group). RESULTS: Of the 3169 included participants, 1428 (45.1%) were female, and the mean (SD; range) age was 21.1 (4.9; 9.5-39.9) years. This study included 1792 individuals at CHR and 1377 healthy controls. Using longitudinal clinical information, 253 in the CHR-PS+ group, 1234 in the CHR-PS- group, and 305 at CHR without follow-up data were identified. Compared with healthy controls, individuals at CHR exhibited widespread lower CT measures (mean [range] Cohen d = -0.13 [-0.17 to -0.09]), but not surface area or subcortical volume. Lower CT measures in the fusiform, superior temporal, and paracentral regions were associated with psychosis conversion (mean Cohen d = -0.22; 95% CI, -0.35 to 0.10). Among healthy controls, compared with those in the CHR-PS+ group, age showed a stronger negative association with left fusiform CT measures (F = 9.8; P < .001; q < .001) and left paracentral CT measures (F = 5.9; P = .005; q = .02). Effect sizes representing lower CT associated with psychosis conversion resembled patterns of CT differences observed in ENIGMA studies of schizophrenia (? = 0.35; 95% CI, 0.12 to 0.55; P = .004) and individuals with 22q11.2 microdeletion syndrome and a psychotic disorder diagnosis (? = 0.43; 95% CI, 0.20 to 0.61; P = .001). CONCLUSIONS AND RELEVANCE: This study provides evidence for widespread subtle, lower CT measures in individuals at CHR. The pattern of CT measure differences in those in the CHR-PS+ group was similar to those reported in other large-scale investigations of psychosis. Additionally, a subset of these regions displayed abnormal age associations. Widespread disruptions in CT coupled with abnormal age associations in those at CHR may point to disruptions in postnatal brain developmental processes.

Published
2021

11. Association of Structural Magnetic Resonance Imaging Measures With Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis

Author

Jalbrzikowski, M., Jalbrzikowski, M., Hayes, R.A., Wood, S.J., Nordholm, D., Zhou, J.H., Fusar-Poli, P., Uhlhaas, P.J., Takahashi, T., Sugranyes, G., Kwak, Y.B., Mathalon, D.H., Katagiri, N., Hooker, C.I., Smigielski, L., Colibazzi, T., Via, E., Tang, J.S., Koike, S., Rasser, P.E., Michel, C., Lebedeva, I., Hegelstad, W.T., de la Fuente-Sandoval, C., Waltz, J.A., Mizrahi, R., Corcoran, C.M., Resch, F., Tamnes, C.K., Haas, S.S., Lemmers-Jansen, I.L.J., Agartz, I., Allen, P., Amminger, G.P., Andreassen, O.A., Atkinson, K., Bachman, P., Baeza, I., Baldwin, H., Bartholomeusz, C.F., Borgwardt, S., Catalano, S., Chee, M.W.L., Chen, X.G., Cho, K.I.K., Cooper, R.E., Cropley, V.L., Dolz, M., Ebdrup, B.H., Fortea, A., Glenthoj, L.B., ENIGMA Clinical High Risk for Psychosis Working Group, Hernaus, Dennis, van Amelsvoort, Thérèse, Jalbrzikowski, M., Jalbrzikowski, M., Hayes, R.A., Wood, S.J., Nordholm, D., Zhou, J.H., Fusar-Poli, P., Uhlhaas, P.J., Takahashi, T., Sugranyes, G., Kwak, Y.B., Mathalon, D.H., Katagiri, N., Hooker, C.I., Smigielski, L., Colibazzi, T., Via, E., Tang, J.S., Koike, S., Rasser, P.E., Michel, C., Lebedeva, I., Hegelstad, W.T., de la Fuente-Sandoval, C., Waltz, J.A., Mizrahi, R., Corcoran, C.M., Resch, F., Tamnes, C.K., Haas, S.S., Lemmers-Jansen, I.L.J., Agartz, I., Allen, P., Amminger, G.P., Andreassen, O.A., Atkinson, K., Bachman, P., Baeza, I., Baldwin, H., Bartholomeusz, C.F., Borgwardt, S., Catalano, S., Chee, M.W.L., Chen, X.G., Cho, K.I.K., Cooper, R.E., Cropley, V.L., Dolz, M., Ebdrup, B.H., Fortea, A., Glenthoj, L.B., ENIGMA Clinical High Risk for Psychosis Working Group, Hernaus, Dennis, and van Amelsvoort, Thérèse

Abstract

IMPORTANCE The ENIGMA clinical high risk (CHR) for psychosis initiative, the largest pooled neuroimaging sample of individuals at CHR to date, aims to discover robust neurobiological markers of psychosis risk.OBJECTIVE To investigate baseline structural neuroimaging differences between individuals at CHR and healthy controls as well as between participants at CHR who later developed a psychotic disorder (CHR-PS+) and those who did not (CHR-PS-).DESIGN, SETTING, AND PARTICIPANTS In this case-control study, baseline T1-weighted magnetic resonance imaging (MRI) data were pooled from 31 international sites participating in the ENIGMA Clinical High Risk for Psychosis Working Group. CHR status was assessed using the Comprehensive Assessment of At-Risk Mental States or Structured Interview for Prodromal Syndromes. MRI scans were processed using harmonized protocols and analyzed within a mega-analysis and meta-analysis framework from January to October 2020.MAIN OUTCOMES AND MEASURES Measures of regional cortical thickness (CT), surface area, and subcortical volumes were extracted from T1-weighted MRI scans. Independent variables were group (CHR group vs control group) and conversion status (CHR-PS+ group vs CHR-PS- group vs control group).RESULTS Of the 3169 included participants, 1428 (45.1%) were female, and the mean (SD; range) age was 21.1 (4.9; 9.5-39.9) years. This study included 1792 individuals at CHR and 1377 healthy controls. Using longitudinal clinical information, 253 in the CHR-PS+ group, 1234 in the CHR-PS- group, and 305 at CHR without follow-up data were identified. Compared with healthy controls, individuals at CHR exhibited widespread lower CT measures (mean [range] Cohen d = -0.13 [-0.17 to -0.09]), but not surface area or subcortical volume. Lower CT measures in the fusiform, superior temporal, and paracentral regions were associated with psychosis conversion (mean Cohen d = -0.22; 95% CI, -0.35 to 0.10). Among healthy controls, compared with those in t

Published
2021

12. Association of Structural Magnetic Resonance Imaging Measures with Psychosis Onset in Individuals at Clinical High Risk for Developing Psychosis: An ENIGMA Working Group Mega-analysis

Author

Jalbrzikowski, M, Hayes, RA, Wood, SJ, Nordholm, D, Zhou, JH, Fusar-Poli, P, Uhlhaas, PJ, Takahashi, T, Sugranyes, G, Kwak, YB, Mathalon, DH, Katagiri, N, Hooker, CI, Smigielski, L, Colibazzi, T, Via, E, Tang, J, Koike, S, Rasser, PE, Michel, C, Lebedeva, I, Hegelstad, WTV, De La Fuente-Sandoval, C, Waltz, JA, Mizrahi, R, Corcoran, CM, Resch, F, Tamnes, CK, Haas, SS, Lemmers-Jansen, ILJ, Agartz, I, Allen, P, Amminger, GP, Andreassen, OA, Atkinson, K, Bachman, P, Baeza, I, Baldwin, H, Bartholomeusz, CF, Borgwardt, S, Catalano, S, Chee, MWL, Chen, X, Cho, KIK, Cooper, RE, Cropley, VL, Dolz, M, Ebdrup, BH, Fortea, A, Glenthøj, LB, Glenthøj, BY, De Haan, L, Hamilton, HK, Harris, MA, Haut, KM, He, Y, Heekeren, K, Heinz, A, Hubl, D, Hwang, WJ, Kaess, M, Kasai, K, Kim, M, Kindler, J, Klaunig, MJ, Koppel, A, Kristensen, TD, Kwon, JS, Lawrie, SM, Lee, J, León-Ortiz, P, Lin, A, Loewy, RL, Ma, X, McGorry, P, McGuire, P, Mizuno, M, Møller, P, Moncada-Habib, T, Muñoz-Samons, D, Nelson, B, Nemoto, T, Nordentoft, M, Omelchenko, MA, Oppedal, K, Ouyang, L, Pantelis, C, Pariente, JC, Raghava, JM, Reyes-Madrigal, F, Roach, BJ, Røssberg, JI, Rössler, W, Salisbury, DF, Sasabayashi, D, Schall, U, Schiffman, J, Schlagenhauf, F, Schmidt, A, Sørensen, ME, Yung, Alison, Jalbrzikowski, M, Hayes, RA, Wood, SJ, Nordholm, D, Zhou, JH, Fusar-Poli, P, Uhlhaas, PJ, Takahashi, T, Sugranyes, G, Kwak, YB, Mathalon, DH, Katagiri, N, Hooker, CI, Smigielski, L, Colibazzi, T, Via, E, Tang, J, Koike, S, Rasser, PE, Michel, C, Lebedeva, I, Hegelstad, WTV, De La Fuente-Sandoval, C, Waltz, JA, Mizrahi, R, Corcoran, CM, Resch, F, Tamnes, CK, Haas, SS, Lemmers-Jansen, ILJ, Agartz, I, Allen, P, Amminger, GP, Andreassen, OA, Atkinson, K, Bachman, P, Baeza, I, Baldwin, H, Bartholomeusz, CF, Borgwardt, S, Catalano, S, Chee, MWL, Chen, X, Cho, KIK, Cooper, RE, Cropley, VL, Dolz, M, Ebdrup, BH, Fortea, A, Glenthøj, LB, Glenthøj, BY, De Haan, L, Hamilton, HK, Harris, MA, Haut, KM, He, Y, Heekeren, K, Heinz, A, Hubl, D, Hwang, WJ, Kaess, M, Kasai, K, Kim, M, Kindler, J, Klaunig, MJ, Koppel, A, Kristensen, TD, Kwon, JS, Lawrie, SM, Lee, J, León-Ortiz, P, Lin, A, Loewy, RL, Ma, X, McGorry, P, McGuire, P, Mizuno, M, Møller, P, Moncada-Habib, T, Muñoz-Samons, D, Nelson, B, Nemoto, T, Nordentoft, M, Omelchenko, MA, Oppedal, K, Ouyang, L, Pantelis, C, Pariente, JC, Raghava, JM, Reyes-Madrigal, F, Roach, BJ, Røssberg, JI, Rössler, W, Salisbury, DF, Sasabayashi, D, Schall, U, Schiffman, J, Schlagenhauf, F, Schmidt, A, Sørensen, ME, and Yung, Alison

Published
2021

15. A Comparison of Novel Developed Centrifugal-Flow and Conventional Pulsatile-Flow Extracorporeal Left Ventricular Assist Devices as Bridging Strategy in Patients with Refractory Heart Failure; Sub-Analysis of NCVC-BTD_01 Trial

Author

Watanabe, T., primary, Seguchi, O., additional, Yanase, M., additional, Fujita, T., additional, Nakajima, S., additional, Kuroda, K., additional, Mochizuki, H., additional, Anegawa, E., additional, Sujino, Y., additional, Yagi, N., additional, Yoshitake, K., additional, Fukushima, S., additional, Saito, T., additional, Tadokoro, N., additional, Kitahata, N., additional, Tsukiya, T., additional, Katagiri, N., additional, Mizuno, T., additional, Onda, K., additional, Tatsumi, E., additional, and Fukushima, N., additional

Published
2021
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28. Long-Term in Vivo Testing of the National Cardiovascular Center Electrohydraulic Total Artificial Heart

Author

Tatsumi, E, primary, Taenaka, Y, additional, Uesho, K, additional, Homma, A, additional, Nishinaka, T, additional, Kakuta, Y, additional, Tsukiya, T, additional, Katagiri, N, additional, Shioya, K, additional, Takahashi, M, additional, Ohnishi, H, additional, Sato, K, additional, Takano, H, additional, Masuzawa, T, additional, Nakamura, M, additional, Tsukahara, K, additional, and Tsuchimoto, K, additional

Published
2001
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33. Novel Extracorporeal Continuous-Flow Ventricular Assist System for Patients with Advanced Heart Failure

Author

Seguchi, O., primary, Fujita, T., additional, Kumai, Y., additional, Kuroda, K., additional, Nakajima, S., additional, Watanabe, T., additional, Yanase, M., additional, Matsumoto, Y., additional, Fukushima, S., additional, Tsukiya, T., additional, Mizuno, T., additional, Katagiri, N., additional, Kakuta, Y., additional, Takewa, Y., additional, Hamasaki, T., additional, Yamamoto, H., additional, Tatsumi, E., additional, Kobayashi, J., additional, and Fukushima, N., additional

Published
2019
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39. P.1.i.042 Cortical thickness changes in individuals at risk of psychosis

Author

Sasabayashi, D., primary, Takayanagi, Y., additional, Nakamura, M., additional, Takahashi, T., additional, Furuichi, A., additional, Kido, M., additional, Nishikawa, Y., additional, Katagiri, N., additional, Sakuma, A., additional, Koike, S., additional, Yamasue, H., additional, Matsumoto, K., additional, Mizuno, M., additional, Kasai, K., additional, and Suzuki, M., additional

Published
2015
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41. Compression and filtration characteristics of yeast-immobilized beads Èprepared using different calcium concentrations.

Author

K.-J. Hwang, P.-Y. Su, Iritani, E., and Katagiri, N.

Subjects
YEAST, FILTERS & filtration, COMPRESSORS, PARTICLES, DEFORMATIONS (Mechanics), COMPRESSION loads
Abstract

Yeast cells were immobilized on calcium alginate beads prepared using different calcium concentrations. The compression properties of the immobilized beads (e.g., softness index and retardation time for compression)were strongly affected by the calcium concentration. The effects of the bead properties on filtration characteristics, such as cake porosity, specific cake filtration resistance, cake compression creeping effect and cake compressibility, were analysed using a dead-end filtration system. The filtration curve of yeast-immobilized beads had an "S" shape, similar to that of soft gel particles. The cake compression behaviour and variation in cake properties were directly reflected on the curve trend. The Voigt in the series model was employed to describe variation in cake porosity with time during a compression. The yeast immobilization increased the bead softness; therefore, the porosity of a cake formed by yeast-immobilized beads was lower than that formed by pure calcium alginate beads. The cakes formed by yeast-immobilized beads possessed a high compressibility of approximately 1.0 and a high softness index of approximately 1.5. The beads prepared using lower calcium concentrations had higher softness, shorter retardation times for compression, higher cake compressibility, lower cake porosity and higher specific cake filtration resistance. The results demonstrated that immobilizing yeast cells on calcium alginate beads is beneficial for retaining higher yeast activity than that of freely suspended yeast. However, the activity levels of yeast immobilized using different calcium concentrations were nearly the same after 3 h. Therefore, using high concentrations of calcium for yeast immobilization is beneficial for improving yeast activity and filtration characteristics. [ABSTRACT FROM AUTHOR]

Published
2016
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