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168 results on '"Kasymjanova G"'

1. EP12.03-02 Previously Treated Advanced-Disease NSCLC KRAS G12C From a Canadian Multi-Institutional Real-World Evidence Database (CARMA)

Author

Zhan, L.J., primary, Barghout, S., additional, Raptis, S., additional, Al-Agha, F., additional, Popovacki, A., additional, Esfahanian, N., additional, Kasymjanova, G., additional, Proulx-Rocray, F., additional, Chan, S., additional, Richardson, M., additional, Brown, M.C., additional, Patel, D., additional, Dean, M.L., additional, Navani, V., additional, Moore, E., additional, Carvery, L., additional, Yan, E., additional, Cleary-Gosine, J., additional, Gibson, A.J., additional, Hubley, L., additional, Balaratnam, K., additional, Ngo, T., additional, Gill, A., additional, Black, M., additional, Sacher, A., additional, Bradbury, P.A., additional, Shepherd, F., additional, Leighl, N., additional, Cheema, P., additional, Kuruvilla, S., additional, Agulnik, J., additional, Banerji, S., additional, Juergens, R., additional, Blais, N., additional, Cheung, W., additional, Wheatley-Price, P., additional, Liu, G., additional, and Snow, S., additional

Published
2023
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4. EP06.01-001 The Longitudinal Impact of COVID-19 on the Diagnosis and Treatment of Lung Cancer at a Canadian Academic Centre: A Retrospective Chart Review

Author

Rizzolo, A., primary, Kasymjanova, G., additional, Pepe, C., additional, Friedmann, J.E., additional, Small, D., additional, Price-Gallagher, C., additional, Spicer, J., additional, Sirois, C., additional, Lecavalier-Barsoum, M., additional, Khalil, S., additional, Wang, H., additional, Spatz, A., additional, Cohen, V., additional, and Agulnik, J., additional

Published
2022
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5. EP04.02-004 The Patient Impact of Liquid Biopsy - Health-Related Quality of Life in Patients Undergoing Liquid Biopsy for Advanced Non-Small Cell Lung Cancer

Author

Corke, L., primary, Laskin, J., additional, Agulnik, J., additional, Laurie, S., additional, Hao, D., additional, Juergens, R., additional, Fernandes, R., additional, Le, L., additional, Law, J., additional, Ezeife, D., additional, Shookoohi, A., additional, Kasymjanova, G., additional, Kelly, S., additional, Nadon, T., additional, Lanman, R., additional, Kiedrowski, L., additional, and Leighl, N., additional

Published
2022
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25. P2.01-04 Reducing Time to Molecular Diagnosis for Advanced NSCLC in the Context of a Reference Testing Center

Author

Ali, A., primary, Singh Tamber, G., additional, Camilleri-Broet, S., additional, Cohen, V., additional, Spicer, J., additional, Wang, H., additional, Chong, G., additional, Munazzit, M., additional, Rousseau, C., additional, Sateren, W., additional, Fernandez, M., additional, Kasymjanova, G., additional, Owen, S., additional, Spatz, A., additional, Van Kempen, L., additional, and Agulnik, J., additional

Published
2018
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29. P3.02-055 Detecting ALK, ROS1 and RET Gene Translocations in Non-Small Cell Lung Cancer (NSCLC) with the NanoString Platform

Author

Wang, H., primary, Rijk, A., additional, Aguirre, M., additional, Wang, A., additional, Wang, K., additional, Dastani, Z., additional, Agulnik, J., additional, Cohen, V., additional, Small, D., additional, Pepe, C., additional, Sakr, L., additional, Kasymjanova, G., additional, Van Kempen, L., additional, and Spatz, A., additional

Published
2017
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30. A012 – CURRENT UTILIZATION OF AEROBIC EXERCISE IN ADULT NEUROLOGICAL REHABILITATION BY CANADIAN PHYSIOTHERAPISTS

Author

Mehta, SP, MacDermid, JC, Butcher, SJ, Pikaluk, BJ, Heynen, NM, Chura, RL, Farthing, JP, Marciniuk, DD, MacKay-Lyons, M, Doyle, L, MacDonald, T, Law, M, Burgos-Martinez, G, Fleet, A, Che, M, MacKenzie, D, Page, S, Boe, S, Woznowski-Vu, A, Preuss, R, Shaw, JA, Connelly, DM, McWilliam, CL, Shaw, J, Sidhu, K, Kearney, C, Keeber, M, McKay, S, Hopkins-Rosseel, D, Bergsma, K, Van Bavel, C, Fricke, M, Swinamer, J, Winn, CS, Tryssenaar, J, Chisholm, BA, Hummelbrunner, JA, Kandler, LS, Jasper, L, Daniels, J, Haennel, RG, Johnson, R, Martin, B, Norman, KE, Booth, R, Chisholm, B, Ellerton, C, Jelley, W, MacPhail, A, Mooney, P, Mori, B, Taipalus, L, Thomas, B, Duval, G, Ghali, S, Nasirian, A, Santillo, G, Yang, XL, Thomas, A, McKinley, P, Kaizer, F, Desveaux, L, Nanavaty, G, Howell, P, Sundar, R, Ryan, J, Verrier, M, Dutton, TL, Langendoen, T, Marshall, J, Coghill, C, Pederson, C, Blechinger, C, Marshall, M, Hamilton, CB, Chesworth, BM, Styles-Tripp, F, Sheps, D, Bury, J, Bouliane, M, Glasgow, R, Otto, D, Luciak-Corea, C, Beaupre, L, Balyk, R, Carson, S, Graham, J, Hopman, W, Parsons, T, Sawant, A, Overend, T, Prasanna, SS, Korner-Bitensky, N, Ahmed, S, O’Donovan, MJ, Driver, H, Randhawa, BK, Farley, BG, Boyd, LA, Henderson, R, Najafi, B, Bansberg, J, Druja, G, Hinch, S, Sikkema, A, Subramanian, SK, LourenÇo, CB, Chilingaryan, G, Sveistrup, H, Levin, MF, King, J, Chamberland, P, Agar, A, Leger, R, Michaels, R, Poitras, R, Rawji, A, Skelton, D, Warren, M, Lavallée, L, LeBlanc, C, McKim, D, Woolnough, A, Cockburn, L, Wango, J, Benuh, E, Cleaver, S, Madill, SJ, Pontbriand-Drolet, S, Prud’homme-Delage, A, Tang, A, Dumoulin, C, Hiemstra, LA, Lafave, M, Kerslake, S, Heard, M, Buchko, G, Mohtadi, N, Auais, M, Eilayyan, O, Mayo, N, Otfinowski, C, Fung, J, Smallhorn, P, Diez, d’Aux N, Shan, He F, Li, L, Ren, Y, Perez, C, Spahija, J, Sadeghi, M, Ebrahimi, S, Maroufi, N, Jamshidi, AA, Chepeha, JC, Magee, DJ, Warren, S, Storey, AST, Brinkman, DM, Bauck, RA, Myrah, AM, Friess, SN, Webber, SC, Taphorn, A, Magnus, CRA, Arnold, CM, Johnston, G, Dal-Bello, Haas V, Basran, J, Krentz, JR, Berardi, D, Brizard, M, Brière, H, Charron, M, Gagnon, I, Tran, T, Kasymjanova, G, Grossman, M, Xenopoulos, T, Jagoe, T, Agulnik, J, Small, D, Kinlin, C, Marlow, T, Donald, LA, Tiessen, S, Cooper, N, Pryse-Phillips, S, Yoshida, K, Teachman, G, Wright, V, Fehlings, D, Young, N, McKeever, P, Parent, EC, Breitkreitz, R, Ladd, J, McIntosh, K, Pauls, D, Urhbach, S, Koppenhaver, S, Alderdice, C, Evans, J, Feldman, S, Robinson, S, White, L, Long, A, McDougall, M, Bonnet, F, Brososky, C, Hopcroft, L, Bester, L, Clement, D, Quigley, A, Sachdeva, M, Rourke, S, Nixon, S, Mendes, P, Robles, P, Mathur, S, Warmington, K, Kennedy, C, Lundon, K, Rozmovits, L, Lineker, S, Shupak, R, Schneider, R, Kennedy, CA, Soever, L, Passalent, L, Katie, Lundon K, Roots, RK, Bainbridge, L, Brown, H, Li, LC, Gillis, K, Augruso, A, Coe, T, O’Neill, A, Radford, L, Gibson, BE, O’Callaghan, L, Bath, B, Janzen, B, Lovo, Grona S, Bourassa, R, Reilly, J, Prendergast, M, Derbyshire, M, Anderson, CM, Friedman, D, Gilbert, G, Lazowski, D, Hurtubise, K, Cote, N, McGlasson, Emery, C, Woodhouse, L, Jones, A, Dickinson, D, Torrance, G, Landry, MD, Murphy, SM, Rivard, LM, Levac, D, Aisen, M, French, EH, Barclay-Goddard, R, Dubouloz, CJ, Schwartz, CE, Jam, B, Manns, PJ, McDonald, A, Ploughman, M, Evans, C, Zhan, J, Stevens, M, Asmundson, Gordon, Yardley, D, Funk, S, Yeung, E, Sinclair, L, Damp, Lowery C, Denehy, L, Ziegler, T, LaRocque, D, Clarke, L, Edge-Hughes, LM, Budiselic, S, Berney, S, Rankin, A, Juricic, M, Peddie, E, Johnson, A, and Seminowicz, DA

Subjects
Innovation in Education, Practice Models and Policy, Divisions, Abstracts, CPA Congress 2012, Proposals, Guest Editorial, Physiotherapy Research: Basic Science through Population Health, Best Practice
Published
2012

32. An exploratory comparative analysis of tyrosine kinase inhibitors or docetaxel in second-line treatment of EGFR wild-type non-small-cell lung cancer: a retrospective real-world practice review at a single tertiary care centre

Author

Ma, K., Cohen, V., Kasymjanova, G., Small, D., Novac, K., Peterson, J., Levit, A., and Agulnik, J.

Subjects
advanced disease, second-line treatment, tyrosine kinase inhibitors, docetaxel, neoplasms, Non-small-cell lung cancer, respiratory tract diseases
Abstract

Treatment for advanced non-small-cell lung cancer (nsclc), especially in patients with wild-type EGFR, remains limited. Recently, erlotinib, a tyrosine kinase inhibitor (tki) targeting EGFR mutation, was approved as second-line treatment in EGFR wild-type nsclc. Despite evidence of better overall survival (os) with chemotherapy than with tki in second-line treatment, data on the use of tki in the real-life clinical setting remain limited. The present practice review of tki use for second- and third-line treatment in EGFR wild-type nsclc also compares clinical outcomes for tki and single-agent docetaxel as second-line treatment. Our retrospective cohort study included patients with EGFR wild-type nsclc treated at the Jewish General Hospital (Montreal, QC) between 2003 and 2013. Patients received a tki (erlotinib or gefitinib) in the second and third line or docetaxel in the second line. For each group, we determined os, disease control rate, progression-free survival (pfs), and event-free survival (efs). The tki group included 145 patients, with 92 receiving second-line treatment. In the control group, 53 patients received docetaxel as second-line therapy. In the tki group, os was 6.0 months, pfs, 2.7 months, and efs, 3.0 months. Comparing second-line treatments, os was 5.3 and 5.0 months respectively (p = 0.88), pfs was 2.5 and 1.8 months respectively (p = 0.041), and efs was 3.0 and 1.7 months respectively (p = 0.009). In our study cohort, second-line therapy for EGFR wild-type nsclc with tki (compared with docetaxel) was associated with statistically better pfs and efs and noninferior os. Those findings raise the question of whether efs should also be considered when choosing second-line treatment in this patient population.

Published
2015
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33. The predictive value of pre-treatment inflammatory markers in advanced non-small-cell lung cancer

Author

Kasymjanova, G., MacDonald, N., Agulnik, J.S., Cohen, V., Pepe, C., Kreisman, H., Sharma, R., and Small, D.

Subjects
Biomarkers in Oncology
Abstract

Accurate prediction of outcome in advanced non-small-cell lung cancer (NSCLC) remains challenging. Even within the same stage and treatment group, survival and response to treatment vary. We set out to determine the predictive value of inflammatory markers C-reactive protein (CRP) and white blood cells (WBCS) in patients with advanced NSCLC.Patients were assigned a prognostic index (PI): 0 for crp 10 mg/L or less and WBCS 11x10⁹/L or less, 1 if one of the two markers was elevated, and 2 if both markers were elevated. We then used chest computed tomography (CT) imaging to evaluate response after 2 cycles of chemotherapy treatment.Of 134 patients, 46 had a PI of 0; 60, a PI of 1; and 28, a PI of 2. Disease progressed in 41 patients. Progression was significantly more frequent among patients with a PI of 2 (p = 0.008). Median survival was 20.0 months for the PI 0 group, 10.4 months for the PI 1 group, and 7.9 months for the PI 2 group (p0.001). The PI was the only significant prognostic factor for survival even after adjustment for performance status, smoking, and weight loss (hazard ratio: 1.57; 95% confidence interval: 1.2 to 2.14; p = 0.004).Inflammatory state correlates significantly with both chemotherapy response and survival in stage IV NSCLC. The PI may provide additional guidance for therapeutic decision-making.

Published
2010

44. Epidermal growth factor receptor (EGFR) mutations detected by denaturing high performance liquid chromatography (dHPLC) in non-small cell lung cancer (NSCLC): Correlation with disease stage and response to tyrosine kinase inhibitors (TKI) therapy

Author

Agulnik, J. S., primary, Cohen, V., additional, Sun, S., additional, Ang, C., additional, Kasymjanova, G., additional, Chong, G., additional, Brandao, G., additional, Pepe, C., additional, Small, D., additional, and Miller, W. H., additional

Published
2008
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48. Clinicopathologic features and prognostic implications of epidermal growth factor receptor (EGFR) gene mutations detected by denaturing high-performance liquid chromatography (dHPLC) in non-small cell lung cancer (NSCLC)

Author

Cohen, V., primary, Agulnik, J. S., additional, Ang, C., additional, Kasymjanova, G., additional, Chong, G., additional, Tejada, N. A., additional, Pepe, C., additional, Batist, G., additional, Small, D., additional, and Miller, W. H., additional

Published
2007
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