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12 results on '"Kasper, Stefanie"'

1. A time-resolved proteomic and prognostic map of COVID-19

Author

Kleinschmidt, Malte, Heim, Katrin M., Millet, Belén, Meyer-Arndt, Lil, Hübner, Ralf H., Andermann, Tim, Doehn, Jan M., Opitz, Bastian, Sawitzki, Birgit, Grund, Daniel, Radünzel, Peter, Schürmann, Mariana, Zoller, Thomas, Alius, Florian, Knape, Philipp, Breitbart, Astrid, Li, Yaosi, Bremer, Felix, Pergantis, Panagiotis, Schürmann, Dirk, Temmesfeld-Wollbrück, Bettina, Wendisch, Daniel, Brumhard, Sophia, Haenel, Sascha S., Conrad, Claudia, Georg, Philipp, Eckardt, Kai-Uwe, Lehner, Lukas, Kruse, Jan M., Ferse, Carolin, Körner, Roland, Spies, Claudia, Edel, Andreas, Weber-Carstens, Steffen, Krannich, Alexander, Zvorc, Saskia, Li, Linna, Behrens, Uwe, Schmidt, Sein, Rönnefarth, Maria, Dang-Heine, Chantip, Röhle, Robert, Lieker, Emma, Kretzler, Lucie, Wirsching, Isabelle, Wollboldt, Christian, Wu, Yinan, Schwanitz, Georg, Hillus, David, Kasper, Stefanie, Olk, Nadine, Horn, Alexandra, Briesemeister, Dana, Treue, Denise, Hummel, Michael, Corman, Victor M., Drosten, Christian, von Kalle, Christof, Demichev, Vadim, Tober-Lau, Pinkus, Lemke, Oliver, Nazarenko, Tatiana, Thibeault, Charlotte, Whitwell, Harry, Röhl, Annika, Freiwald, Anja, Szyrwiel, Lukasz, Ludwig, Daniela, Correia-Melo, Clara, Aulakh, Simran Kaur, Helbig, Elisa T., Stubbemann, Paula, Lippert, Lena J., Grüning, Nana-Maria, Blyuss, Oleg, Vernardis, Spyros, White, Matthew, Messner, Christoph B., Joannidis, Michael, Sonnweber, Thomas, Klein, Sebastian J., Pizzini, Alex, Wohlfarter, Yvonne, Sahanic, Sabina, Hilbe, Richard, Schaefer, Benedikt, Wagner, Sonja, Mittermaier, Mirja, Machleidt, Felix, Garcia, Carmen, Ruwwe-Glösenkamp, Christoph, Lingscheid, Tilman, Bosquillon de Jarcy, Laure, Stegemann, Miriam S., Pfeiffer, Moritz, Jürgens, Linda, Denker, Sophy, Zickler, Daniel, Enghard, Philipp, Zelezniak, Aleksej, Campbell, Archie, Hayward, Caroline, Porteous, David J., Marioni, Riccardo E., Uhrig, Alexander, Müller-Redetzky, Holger, Zoller, Heinz, Löffler-Ragg, Judith, Keller, Markus A., Tancevski, Ivan, Timms, John F., Zaikin, Alexey, Hippenstiel, Stefan, Ramharter, Michael, Witzenrath, Martin, Suttorp, Norbert, Lilley, Kathryn, Mülleder, Michael, Sander, Leif Erik, Ralser, Markus, and Kurth, Florian

Published
2021
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2. Delayed Antibody and T-Cell Response to BNT162b2 Vaccination in the Elderly, Germany

Author

Schwarz, Tatjana, Tober-Lau, Pinkus, Hillus, David, Helbig, Elisa T., Lippert, Lena J., Thibeault, Charlotte, Koch, Willi, Landgraf, Irmgard, Michel, Janine, Bergfeld, Leon, Niemeyer, Daniela, Muhlemann, Barbara, Conrad, Claudia, Dang-Heine, Chantip, Kasper, Stefanie, Munn, Friederike, Kappert, Kai, Nitsche, Andreas, Tauber, Rudolf, Schmidt, Sein, Kopankiewicz, Piotr, Bias, Harald, Seybold, Joachim, von Kalle, Christof, Jones, Terry C., Suttorp, Norbert, Drosten, Christian, Sander, Leif Erik, Corman, Victor M., and Kurth, Florian

Subjects
Antigen-antibody reactions -- Health aspects, Aged patients -- Care and treatment, T cells -- Health aspects, Immune response -- Health aspects, Health
Abstract

We detected delayed and reduced antibody and T-cell responses after BNT162b2 vaccination in 71 elderly persons (median age 81 years) compared with 123 healthcare workers (median age 34 years) in [...]

Published
2021
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3. Outbreak of SARS-CoV-2 B.1.1.7 Lineage after Vaccination in Long-Term Care Facility, Germany, February-March 2021

Author

Tober-Lau, Pinkus, Schwarz, Tatjana, Hillus, David, Spieckermann, Jana, Helbig, Elisa T., Lippert, Lena J., Thibeault, Charlotte, Koch, Willi, Bergfeld, Leon, Niemeyer, Daniela, Muhlemann, Barbara, Conrad, Claudia, Kasper, Stefanie, Munn, Friederike, Kunitz, Frank, Jones, Terry C., Suttorp, Norbert, Drosten, Christian, Sander, Leif Erik, Kurth, Florian, and Corman, Victor M.

Subjects
Vaccination -- Patient outcomes, Epidemics -- Risk factors -- Demographic aspects -- Control -- Germany, Long-term care facilities -- Management -- Safety and security measures, Company business management, Health
Abstract

One week after second vaccinations were administered, an outbreak of B.1.1.7 lineage severe acute respiratory syndrome coronavirus 2 infections occurred in a long-term care facility in Berlin, Germany, affecting 16/20 [...]

Published
2021
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7. A time-resolved proteomic and prognostic map of COVID-19

Author

Demichev, Vadim, primary, Tober-Lau, Pinkus, additional, Lemke, Oliver, additional, Nazarenko, Tatiana, additional, Thibeault, Charlotte, additional, Whitwell, Harry, additional, Röhl, Annika, additional, Freiwald, Anja, additional, Szyrwiel, Lukasz, additional, Ludwig, Daniela, additional, Correia-Melo, Clara, additional, Aulakh, Simran Kaur, additional, Helbig, Elisa T., additional, Stubbemann, Paula, additional, Lippert, Lena J., additional, Grüning, Nana-Maria, additional, Blyuss, Oleg, additional, Vernardis, Spyros, additional, White, Matthew, additional, Messner, Christoph B., additional, Joannidis, Michael, additional, Sonnweber, Thomas, additional, Klein, Sebastian J., additional, Pizzini, Alex, additional, Wohlfarter, Yvonne, additional, Sahanic, Sabina, additional, Hilbe, Richard, additional, Schaefer, Benedikt, additional, Wagner, Sonja, additional, Mittermaier, Mirja, additional, Machleidt, Felix, additional, Garcia, Carmen, additional, Ruwwe-Glösenkamp, Christoph, additional, Lingscheid, Tilman, additional, Bosquillon de Jarcy, Laure, additional, Stegemann, Miriam S., additional, Pfeiffer, Moritz, additional, Jürgens, Linda, additional, Denker, Sophy, additional, Zickler, Daniel, additional, Enghard, Philipp, additional, Zelezniak, Aleksej, additional, Campbell, Archie, additional, Hayward, Caroline, additional, Porteous, David J., additional, Marioni, Riccardo E., additional, Uhrig, Alexander, additional, Müller-Redetzky, Holger, additional, Zoller, Heinz, additional, Löffler-Ragg, Judith, additional, Keller, Markus A., additional, Tancevski, Ivan, additional, Timms, John F., additional, Zaikin, Alexey, additional, Hippenstiel, Stefan, additional, Ramharter, Michael, additional, Witzenrath, Martin, additional, Suttorp, Norbert, additional, Lilley, Kathryn, additional, Mülleder, Michael, additional, Sander, Leif Erik, additional, Ralser, Markus, additional, Kurth, Florian, additional, Kleinschmidt, Malte, additional, Heim, Katrin M., additional, Millet, Belén, additional, Meyer-Arndt, Lil, additional, Hübner, Ralf H., additional, Andermann, Tim, additional, Doehn, Jan M., additional, Opitz, Bastian, additional, Sawitzki, Birgit, additional, Grund, Daniel, additional, Radünzel, Peter, additional, Schürmann, Mariana, additional, Zoller, Thomas, additional, Alius, Florian, additional, Knape, Philipp, additional, Breitbart, Astrid, additional, Li, Yaosi, additional, Bremer, Felix, additional, Pergantis, Panagiotis, additional, Schürmann, Dirk, additional, Temmesfeld-Wollbrück, Bettina, additional, Wendisch, Daniel, additional, Brumhard, Sophia, additional, Haenel, Sascha S., additional, Conrad, Claudia, additional, Georg, Philipp, additional, Eckardt, Kai-Uwe, additional, Lehner, Lukas, additional, Kruse, Jan M., additional, Ferse, Carolin, additional, Körner, Roland, additional, Spies, Claudia, additional, Edel, Andreas, additional, Weber-Carstens, Steffen, additional, Krannich, Alexander, additional, Zvorc, Saskia, additional, Li, Linna, additional, Behrens, Uwe, additional, Schmidt, Sein, additional, Rönnefarth, Maria, additional, Dang-Heine, Chantip, additional, Röhle, Robert, additional, Lieker, Emma, additional, Kretzler, Lucie, additional, Wirsching, Isabelle, additional, Wollboldt, Christian, additional, Wu, Yinan, additional, Schwanitz, Georg, additional, Hillus, David, additional, Kasper, Stefanie, additional, Olk, Nadine, additional, Horn, Alexandra, additional, Briesemeister, Dana, additional, Treue, Denise, additional, Hummel, Michael, additional, Corman, Victor M., additional, Drosten, Christian, additional, and von Kalle, Christof, additional

Published
2021
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9. Untersuchung der Wirksamkeit und Zytotoxizität eines neuartigen antimikrobiellen Peptids

Author

Bormann, Nicole, Schön, Larissa, Kasper, Stefanie, Hilpert, Kai, Volkmer, Rudolf, Moter, Annette, and Wildemann, Britt

Subjects
Zytotoxizität, ddc: 610, Biofilm, 610 Medical sciences, Medicine, minimale Hemmkonzentration, Antimikrobielles Peptid
Abstract

Fragestellung: Infektionen des Knochens sind eine schwerwiegende Komplikation und besonders die Biofilmbildung auf Implantaten stellt eine Herausforderung im klinischen Alltag dar. Antimikrobielle Peptide könnten eine Alternative zu den klassischen Antibiotika darstellen, da sie ein breites Wirkspektrum[zum vollständigen Text gelangen Sie über die oben angegebene URL], Deutscher Kongress für Orthopädie und Unfallchirurgie (DKOU 2015)

Published
2015

10. Activity of daptomycin- and vancomycin-loaded poly-epsilon-caprolactone microparticles against mature staphylococcal biofilms

Author

Ferreira,Inês, Bettencourt,Ana, Gonçalves,Lídia, Kasper,Stefanie, Bétrisey,Bertrand, Kikhney,Judith, Moter,Annette, Trampuz,Andrej, Almeida,António J, Ferreira,Inês, Bettencourt,Ana, Gonçalves,Lídia, Kasper,Stefanie, Bétrisey,Bertrand, Kikhney,Judith, Moter,Annette, Trampuz,Andrej, and Almeida,António J

Abstract

Inês Santos Ferreira,1 Ana F Bettencourt,1 Lídia MD Gonçalves,1 Stefanie Kasper,2 Bertrand Bétrisey,3 Judith Kikhney,2 Annette Moter,2 Andrej Trampuz,4 António J Almeida1 1Research Institute for Medicines (iMed.ULisboa), Faculty of Pharmacy, University of Lisbon, Lisbon, Portugal; 2Biofilmcenter, German Heart Institute Berlin, Berlin, Germany; 3Infectious Diseases Service, Department of Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland; 4Center for Musculoskeletal Surgery, Charité – University Medicine Berlin, Berlin, Germany Abstract: The aim of the present study was to develop novel daptomycin-loaded poly-epsilon-caprolactone (PCL) microparticles with enhanced antibiofilm activity against mature biofilms of clinically relevant bacteria, methicillin-resistant Staphylococcus aureus (MRSA) and polysaccharide intercellular adhesin-positive Staphylococcus epidermidis. Daptomycin was encapsulated into PCL microparticles by a double emulsion-solvent evaporation method. For comparison purposes, formulations containing vancomycin were also prepared. Particle morphology, size distribution, encapsulation efficiency, surface charge, thermal behavior, and in vitro release were assessed. All formulations exhibited a spherical morphology, micro­meter size, and negative surface charge. From a very early time stage, the released concentrations of daptomycin and vancomycin were higher than the minimal inhibitory concentration and continued so up to 72 hours. Daptomycin presented a sustained release profile with increasing concentrations of the drug being released up to 72 hours, whereas the release of vancomycin stabilized at 24 hours. The antibacterial activity of the microparticles was assessed by isothermal microcalorimetry against planktonic and sessile MRSA and S. epidermidis. Regarding planktonic bacteria, daptomycin-loaded PCL microparticles presented the highest antiba

Published
2015

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