2,032 results on '"Karlsson, Mats O."'
Search Results
2. Physiologically-based pharmacokinetic models versus allometric scaling for prediction of tyrosine-kinase inhibitor exposure from adults to children
3. Efficiency of Multivariate Tests in Trials in Progressive Supranuclear Palsy
4. Pharmacogenetic Testing or Therapeutic Drug Monitoring: A Quantitative Framework
5. Increase in peg-asparaginase clearance as a predictor for inactivation in patients with acute lymphoblastic leukemia
6. Model-Informed Precision Dosing to Reduce Vincristine-Induced Peripheral Neuropathy in Pediatric Patients: A Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis
7. Characterization of anti-drug antibody dynamics using a bivariate mixed hidden-markov model by nonlinear-mixed effects approach
8. Training the next generation of pharmacometric modelers: a multisector perspective
9. Comparison of Two Methods for Determining Item Characteristic Functions and Latent Variable Time-Course for Pharmacometric Item Response Models
10. Generation and application of avatars in pharmacometric modelling
11. Joint longitudinal model-based meta-analysis of FEV1 and exacerbation rate in randomized COPD trials
12. Correction to: Training the next generation of pharmacometric modelers: a multisector perspective
13. Characterizing Absorption Properties of Dispersible Pretomanid Tablets Using Population Pharmacokinetic Modelling
14. A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study
15. Population Pharmacokinetics of Delamanid and its Main Metabolite DM-6705 in Drug-Resistant Tuberculosis Patients Receiving Delamanid Alone or Coadministered with Bedaquiline
16. Improved Confidence in a Confirmatory Stage by Application of Item-Based Pharmacometrics Model: Illustration with a Phase III Active Comparator-Controlled Trial in COPD Patients
17. Evaluating darunavir/ritonavir dosing regimens for HIV-positive pregnant women using semi-mechanistic pharmacokinetic modelling
18. A fully automatic tool for development of population pharmacokinetic models.
19. Evaluation of model‐integrated evidence approaches for pharmacokinetic bioequivalence studies using model averaging methods.
20. Development and comparison of model‐integrated evidence approaches for bioequivalence studies with pharmacokinetic end points.
21. A pharmacometric multistate model for predicting long-term treatment outcomes of patients with pulmonary TB.
22. Predicting the Long‐Term Effects of Therapeutic Neutralization of Oncostatin M on Human Hematopoiesis.
23. Item performance of the scale for the assessment and rating of ataxia in rare and ultra‐rare genetic ataxias.
24. Suboptimal Antituberculosis Drug Concentrations and Outcomes in Small and HIV‐Coinfected Children in India: Recommendations for Dose Modifications
25. Item response theory analysis of daytime sleepiness as a symptom of obstructive sleep apnea
26. Evaluation of covariate effects in item response theory models
27. Population Pharmacokinetics of Cladribine in Patients with Multiple Sclerosis
28. Properties of the full random-effect modeling approach with missing covariate data
29. Pharmacometrics-Based Considerations for the Design of a Pharmacogenomic Clinical Trial Assessing Irinotecan Safety
30. A general model for cell death and biomarker release from injured tissues
31. Covariate modeling in pharmacometrics: General points for consideration.
32. Model-Informed Precision Dosing to Reduce Vincristine-Induced Peripheral Neuropathy in Pediatric Patients: A Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis
33. Properties of the full random‐effect modeling approach with missing covariate data
34. Physiologically-based pharmacokinetic models versus allometric scaling for prediction of tyrosine-kinase inhibitor exposure from adults to children
35. Characterization of anti-drug antibody dynamics using a bivariate mixed hidden-markov model by nonlinear-mixed effects approach
36. Comparison of covariate selection methods with correlated covariates: prior information versus data information, or a mixture of both?
37. Performance of longitudinal item response theory models in shortened or partial assessments
38. A longitudinal item response model for Aberrant Behavior Checklist (ABC) data from children with autism
39. Prediction of exposure-driven myelotoxicity of continuous infusion 5-fluorouracil by a semi-physiological pharmacokinetic–pharmacodynamic model in gastrointestinal cancer patients
40. Improved Decision-Making Confidence Using Item-Based Pharmacometric Model: Illustration with a Phase II Placebo-Controlled Trial
41. An Item Response Theory–Informed Strategy to Model Total Score Data from Composite Scales
42. Assessing Treatment Effects with Pharmacometric Models: A New Method that Addresses Problems with Standard Assessments
43. Correction to: Training the next generation of pharmacometric modelers: a multisector perspective
44. Training the next generation of pharmacometric modelers: a multisector perspective
45. Bounded Integer Modeling of Symptom Scales Specific to Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia
46. Model-Based Estimates of the Effects of Efavirenz on Bedaquiline Pharmacokinetics and Suggested Dose Adjustments for Patients Coinfected with HIV and Tuberculosis
47. Development of visual predictive checks accounting for multimodal parameter distributions in mixture models
48. The Clinical Pharmacology of Cladribine Tablets for the Treatment of Relapsing Multiple Sclerosis
49. Comparison of Precision and Accuracy of Five Methods to Analyse Total Score Data
50. Standard Error of Empirical Bayes Estimate in NONMEM® VI.
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