6,539 results on '"Karl K. So"'
Search Results
2. Characterizing and modeling the influence of geometry on the performance of superconducting nanowire cryotrons
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Simon, Alejandro, Foster, Reed, Medeiros, Owen, Castellani, Matteo, Batson, Emma, and Berggren, Karl K.
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Condensed Matter - Superconductivity ,Physics - Applied Physics - Abstract
The scaling of superconducting nanowire-based devices to larger arrays is often limited by the cabling required to interface with each device. Cryogenic integrated circuits constructed from nanowire cryotrons, or nanocryotrons, can address this limitation by performing signal processing on chip. In this study, we characterize key performance metrics of the nanocryotron to elucidate its potential as a logical element in cryogenic integrated circuits and develop an electro-thermal model to connect material parameters with device performance. We find that the performance of the nanocryotron depends significantly on the device geometry, and trade-offs are associated with optimizing the gain, jitter, and energy dissipation. We demonstrate that nanocryotrons fabricated on niobium nitride can achieve a grey zone less than 210 nA wide for a 5 ns long input pulse corresponding to a maximum achievable gain of 48 dB, an energy dissipation of less than 20 aJ per operation, and a jitter of less than 60 ps., Comment: 5 pages, 5 figures
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- 2024
3. Analysis and Applications of a Heralded Electron Source
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Koppell, Stewart A., Simonaitis, John W., Krielaart, Maurice A. R., Putnam, William P., Berggren, Karl K., and Keathley, Phillip D.
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Physics - Applied Physics - Abstract
We analytically describe the noise properties of a heralded electron source made from a standard electron gun, a weak photonic coupler, a single photon counter, and an electron energy filter. We argue the traditional heralding figure of merit, the Klyshko efficiency, is an insufficient statistic for characterizing performance in dose-control and dose-limited applications. Instead, we describe the sub-Poissonian statistics of the source using the fractional reduction in variance and the fractional increase in Fisher Information. Using these figures of merit, we discuss the engineering requirements for efficient heralding and evaluate potential applications using simple models of electron lithography, bright-field scanning transmission electron microscopy (BFSTEM), and scanning electron microscopy (SEM). We find that the advantage in each of these applications is situational, but potentially significant: dynamic control of the trade-off between write speed and shot noise in electron lithography; an order of magnitude dose reduction in BFSTEM for thin samples (e.g. 2D materials); and a doubling of dose efficiency for wall-steepness estimation in SEM.
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- 2024
4. A superconducting full-wave bridge rectifier
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Castellani, Matteo, Medeiros, Owen, Buzzi, Alessandro, Foster, Reed A., Colangelo, Marco, and Berggren, Karl K.
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Physics - Applied Physics - Abstract
Superconducting thin-film electronics are attractive for their low power consumption, fast operating speeds, and ease of interface with cryogenic systems such as single-photon detector arrays, and quantum computing devices. However, the lack of a reliable superconducting two-terminal asymmetric device, analogous to a semiconducting diode, limits the development of power-handling circuits, fundamental for scaling up these technologies. Existing efforts to date have been limited to single-diode proofs of principle and lacked integration of multiple controllable and reproducible devices to form complex circuits. Here, we demonstrate a robust superconducting diode with tunable polarity using the asymmetric Bean-Livingston surface barrier in niobium nitride micro-bridges, achieving a 43% rectification efficiency. We then realize and integrate several such diodes into a bridge rectifier circuit on a single microchip that performs continuous full-wave rectification up to 3 MHz and AC-to-DC conversion in burst mode at 50 MHz with an estimated peak power efficiency of 60%.
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- 2024
5. Self-regulated radius of spontaneously formed GaN nanowires in molecular beam epitaxy
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Fernández-Garrido, Sergio, Kaganer, Vladimir M., Sabelfeld, Karl K., Gotschke, Tobias, Grandal, Javier, Calleja, Enrique, Geelhaar, Lutz, and Brandt, Oliver
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Condensed Matter - Materials Science - Abstract
We investigate the axial and radial growth of GaN nanowires upon a variation of the Ga flux during molecular beam epitaxial growth. An increase in the Ga flux promotes radial growth without affecting the axial growth rate. In contrast, a decrease in the Ga flux reduces the axial growth rate without any change in the radius. These results are explained by a kinetic growth model that accounts for both the diffusion of Ga adatoms along the side facets towards the nanowire tip and the finite amount of active N available for the growth. The model explains the formation of a new equilibrium nanowire radius after increasing the Ga flux and provides an explanation for two well known but so far not understood experimental facts: the necessity of effectively N-rich conditions for the spontaneous growth of GaN nanowires and the increase in nanowire radius with increasing III/V flux ratios.
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- 2024
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6. Improvements of readout signal integrity in mid-infrared superconducting nanowire single photon detectors
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Patel, Sahil R., Colangelo, Marco, Beyer, Andrew D., Taylor, Gregor G., Allmaras, Jason P., Wollman, Emma E., Shaw, Matthew D., Berggren, Karl K., and Korzh, Boris
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Physics - Instrumentation and Detectors ,Physics - Applied Physics - Abstract
Superconducting nanowire single-photon detectors (SNSPDs) with high timing resolution and low background counts in the mid infrared (MIR) have the potential to open up numerous opportunities in fields such as exoplanet searches, direct dark matter detection, physical chemistry, and remote sensing. One challenge in pushing SNSPD sensitivity to the MIR is a decrease in the signal-to-noise ratio (SNR) of the readout signal as the critical currents become increasingly smaller. We overcome this trade-off with a new device architecture that employs impedance matching tapers and superconducting nanowire avalanche photodetectors to demonstrate increased SNR while maintaining saturated internal detection efficiency at 7.4 {\mu}m and getting close to saturation at 10.6 {\mu}m. This work provides a novel platform for pushing SNSPD sensitivity to longer wavelengths while improving the scalability of the readout electronics.
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- 2024
7. Dosimetric calibration of an anatomically specific ultra-high dose rate electron irradiation platform for preclinical FLASH radiobiology experiments
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Wang, Jinghui, Melemenidis, Stavros, Manjappa, Rakesh, Viswanathan, Vignesh, Ashraf, Ramish M., Levy, Karen, Skinner, Lawrie, Soto, Luis A., Chow, Stephanie, Lau, Brianna, Ko, Ryan B., Graves, Edward E., Yu, Amy S., Bush, Karl K., Surucu, Murat, Rankin, Erinn B., Loo Jr, Billy W., Schüler, Emil, and Maxim, Peter G.
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Physics - Medical Physics - Abstract
We characterized the dosimetric properties of a clinical linear accelerator configured to deliver ultra-high dose rate (UHDR) irradiation to mice and cell-culture FLASH radiobiology experiments. UHDR electron beams were controlled by a microcontroller and relay interfaced with the respiratory gating system. We produced beam collimators with indexed stereotactic mouse positioning devices to provide anatomically specific preclinical treatments. Treatment delivery was monitored directly with an ionization chamber, and charge measurements were correlated with radiochromic film at the entry surface of the mice. The setup for conventional (CONV) dose rate irradiation was similar but the source-to-surface distance was longer. Monte Carlo simulations and film dosimetry were used to characterize beam properties and dose distributions. The mean electron beam energies before the flattening filter were 18.8 MeV (UHDR) and 17.7 MeV (CONV), with corresponding values at the mouse surface of 17.2 MeV and 16.2 MeV. The charges measured with an external ion chamber were linearly correlated with the mouse entrance dose. Use of relay gating for pulse control initially led to a delivery failure rate of 20% ($+/-$ 1 pulse); adjustments to account for the linac latency improved this rate to <1/20. Beam field sizes for two anatomically specific mouse collimators (4x4 $cm^2$ for whole-abdomen and 1.5x1.5 $cm^2$ for unilateral lung irradiation) were accurate within <5% and had low radiation leakage (<4%). Normalizing the dose at the center of the mouse (~0.75 cm depth) produced UHDR and CONV doses to the irradiated volumes with >95% agreement. We successfully configured a clinical linear accelerator for increased output and developed a robust preclinical platform for anatomically specific irradiation, with highly accurate and precise temporal and spatial dose delivery, for both CONV and UHDR applications., Comment: Jinghui Wang and Stavros Melemenidis are co-first authors, and Emil Sch\"uler and Peter G. Maxim are co-senior/co-corresponding authors
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- 2023
8. Quantum Sensors for High Energy Physics
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Chou, Aaron, Irwin, Kent, Maruyama, Reina H., Baker, Oliver K., Bartram, Chelsea, Berggren, Karl K., Cancelo, Gustavo, Carney, Daniel, Chang, Clarence L., Cho, Hsiao-Mei, Garcia-Sciveres, Maurice, Graham, Peter W., Habib, Salman, Harnik, Roni, Harris, J. G. E., Hertel, Scott A., Hume, David B., Khatiwada, Rakshya, Kovachy, Timothy L., Kurinsky, Noah, Lamoreaux, Steve K., Lehnert, Konrad W., Leibrandt, David R., Li, Dale, Loer, Ben, Martínez-Rincón, Julián, McCuller, Lee, Moore, David C., Mueller, Holger, Pena, Cristian, Pooser, Raphael C., Pyle, Matt, Rajendran, Surjeet, Safronova, Marianna S., Schuster, David I., Shaw, Matthew D., Spiropulu, Maria, Stankus, Paul, Sushkov, Alexander O., Winslow, Lindley, Xie, Si, and Zurek, Kathryn M.
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High Energy Physics - Experiment ,High Energy Physics - Phenomenology ,Quantum Physics - Abstract
Strong motivation for investing in quantum sensing arises from the need to investigate phenomena that are very weakly coupled to the matter and fields well described by the Standard Model. These can be related to the problems of dark matter, dark sectors not necessarily related to dark matter (for example sterile neutrinos), dark energy and gravity, fundamental constants, and problems with the Standard Model itself including the Strong CP problem in QCD. Resulting experimental needs typically involve the measurement of very low energy impulses or low power periodic signals that are normally buried under large backgrounds. This report documents the findings of the 2023 Quantum Sensors for High Energy Physics workshop which identified enabling quantum information science technologies that could be utilized in future particle physics experiments, targeting high energy physics science goals., Comment: 63 pages, 8 figures, Quantum Sensors for HEP workshop report, April 26-28, 2023
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- 2023
9. Coherent control of a superconducting qubit using light
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Warner, Hana K., Holzgrafe, Jeffrey, Yankelevich, Beatriz, Barton, David, Poletto, Stefano, Xin, C. J., Sinclair, Neil, Zhu, Di, Sete, Eyob, Langley, Brandon, Batson, Emma, Colangelo, Marco, Shams-Ansari, Amirhassan, Joe, Graham, Berggren, Karl K., Jiang, Liang, Reagor, Matthew, and Loncar, Marko
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Quantum Physics - Abstract
Quantum science and technology promise the realization of a powerful computational resource that relies on a network of quantum processors connected with low loss and low noise communication channels capable of distributing entangled states [1,2]. While superconducting microwave qubits (3-8 GHz) operating in cryogenic environments have emerged as promising candidates for quantum processor nodes due to their strong Josephson nonlinearity and low loss [3], the information between spatially separated processor nodes will likely be carried at room temperature via telecommunication photons (200 THz) propagating in low loss optical fibers. Transduction of quantum information [4-10] between these disparate frequencies is therefore critical to leverage the advantages of each platform by interfacing quantum resources. Here, we demonstrate coherent optical control of a superconducting qubit. We achieve this by developing a microwave-optical quantum transducer that operates with up to 1.18% conversion efficiency (1.16% cooperativity) and demonstrate optically-driven Rabi oscillations (2.27 MHz) in a superconducting qubit without impacting qubit coherence times (800 ns). Finally, we discuss outlooks towards using the transducer to network quantum processor nodes.
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- 2023
10. Enhanced feature matching in single-cell proteomics characterizes IFN-γ response and co-existence of cell states
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Karl K. Krull, Syed Azmal Ali, and Jeroen Krijgsveld
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Science - Abstract
Abstract Proteome analysis by data-independent acquisition (DIA) has become a powerful approach to obtain deep proteome coverage, and has gained recent traction for label-free analysis of single cells. However, optimal experimental design for DIA-based single-cell proteomics has not been fully explored, and performance metrics of subsequent data analysis tools remain to be evaluated. Therefore, we here formalize and comprehensively evaluate a DIA data analysis strategy that exploits the co-analysis of low-input samples with a so-called matching enhancer (ME) of higher input, to increase sensitivity, proteome coverage, and data completeness. We assess the matching specificity of DIA-ME by a two-proteome model, and demonstrate that false discovery and false transfer are maintained at low levels when using DIA-NN software, while preserving quantification accuracy. We apply DIA-ME to investigate the proteome response of U-2 OS cells to interferon gamma (IFN-γ) in single cells, and recapitulate the time-resolved induction of IFN-γ response proteins as observed in bulk material. Moreover, we uncover co- and anti-correlating patterns of protein expression within the same cell, indicating mutually exclusive protein modules and the co-existence of different cell states. Collectively our data show that DIA-ME is a powerful, scalable, and easy-to-implement strategy for single-cell proteomics.
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- 2024
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11. Lightwave-Electronic Harmonic Frequency Mixing
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Yeung, Matthew, Chou, Lu-Ting, Turchetti, Marco, Ritzkowsky, Felix, Berggren, Karl K., and Keathley, Philip. D.
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Physics - Optics - Abstract
Electronic frequency mixers are fundamental building blocks of electronic systems. Harmonic frequency mixing in particular enables broadband electromagnetic signal analysis across octaves of spectrum using a single local oscillator. However, conventional harmonic frequency mixers do not operate beyond hundreds of GHz to a few THz. If extended to the petahertz scale in a compact and scalable form, harmonic mixers would enable field-resolved optical signal analysis spanning octaves of spectra in a monolithic device without the need for frequency conversion using nonlinear crystals. Here we demonstrate lightwave-electronic harmonic frequency mixing beyond 0.350 PHz using plasmonic nanoantennas. We demonstrate that the mixing process enables complete, field-resolved detection of spectral content far outside that of the local oscillator, greatly extending the range of detectable frequencies compared to conventional heterodyning techniques. Our work has important implications for applications where optical signals of interest exhibit coherent femtosecond-scale dynamics spanning multiple harmonics.
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- 2023
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12. Enhanced feature matching in single-cell proteomics characterizes IFN-γ response and co-existence of cell states
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Krull, Karl K., Ali, Syed Azmal, and Krijgsveld, Jeroen
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- 2024
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13. Single-photon detection using large-scale high-temperature MgB2 sensors at 20 K
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Charaev, Ilya, Batson, Emma K., Cherednichenko, Sergey, Reidy, Kate, Drakinskiy, Vladimir, Yu, Yang, Lara-Avila, Samuel, Thomsen, Joachim D., Colangelo, Marco, Incalza, Francesca, Ilin, Konstantin, Schilling, Andreas, and Berggren, Karl K.
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- 2024
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14. Nanocryotron ripple counter integrated with a superconducting nanowire single-photon detector for megapixel arrays
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Castellani, Matteo, Medeiros, Owen, Foster, Reed A., Buzzi, Alessandro, Colangelo, Marco, Bienfang, Joshua C., Restelli, Alessandro, and Berggren, Karl K.
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Physics - Applied Physics - Abstract
Decreasing the number of cables that bring heat into the cryostat is a critical issue for all cryoelectronic devices. Especially, arrays of superconducting nanowire single-photon detectors (SNSPDs) could require more than $10^6$ readout lines. Performing signal processing operations at low temperatures could be a solution. Nanocryotrons, superconducting nanowire three-terminal devices, are good candidates for integrating sensing and electronics on the same technological platform as SNSPDs in photon-counting applications. In this work, we demonstrated that it is possible to read out, process, encode, and store the output of SNSPDs using exclusively superconducting nanowires. In particular, we present the design and development of a nanocryotron ripple counter that detects input voltage spikes and converts the number of pulses to an $N$-digit value. The counting base can be tuned from 2 to higher values, enabling higher maximum counts without enlarging the circuit. As a proof-of-principle, we first experimentally demonstrated the building block of the counter, an integer-$N$ frequency divider with $N$ ranging from 2 to 5. Then, we demonstrated photon-counting operations at 405 nm and 1550 nm by coupling an SNSPD with a 2-digit nanocryotron counter partially integrated on-chip. The 2-digit counter could operate in either base 2 or base 3 with a bit error rate lower than $2 \times 10^{-4}$ and a count rate of $10^7\,$s$^{-1}$. We simulated circuit architectures for integrated readout of the counter state, and we evaluated the capabilities of reading out an SNSPD megapixel array that would collect up to $10^{12}$ counts per second. The results of this work, combined with our recent publications on a nanocryotron shift register and logic gates, pave the way for the development of nanocryotron processors, from which multiple superconducting platforms may benefit.
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- 2023
15. Large active-area superconducting microwire detector array with single-photon sensitivity in the near-infrared
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Luskin, Jamie S., Schmidt, Ekkehart, Korzh, Boris, Beyer, Andrew D., Bumble, Bruce, Allmaras, Jason P., Walter, Alexander B., Wollman, Emma E., Narváez, Lautaro, Verma, Varun B., Nam, Sae Woo, Charaev, Ilya, Colangelo, Marco, Berggren, Karl K., Peña, Cristián, Spiropulu, Maria, Garcia-Sciveres, Maurice, Derenzo, Stephen, and Shaw, Matthew D.
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Physics - Instrumentation and Detectors - Abstract
Superconducting nanowire single photon detectors (SNSPDs) are the highest-performing technology for time-resolved single-photon counting from the UV to the near-infrared. The recent discovery of single-photon sensitivity in micrometer-scale superconducting wires is a promising pathway to explore for large active area devices with application to dark matter searches and fundamental physics experiments. We present 8-pixel $1 mm^2$ superconducting microwire single photon detectors (SMSPDs) with $1\,\mathrm{\mu m}$-wide wires fabricated from WSi and MoSi films of various stoichiometries using electron-beam and optical lithography. Devices made from all materials and fabrication techniques show saturated internal detection efficiency at 1064 nm in at least one pixel, and the best performing device made from silicon-rich WSi shows single-photon sensitivity in all 8 pixels and saturated internal detection efficiency in 6/8 pixels. This detector is the largest reported active-area SMSPD or SNSPD with near-IR sensitivity published to date, and the first report of an SMSPD array. By further optimizing the photolithography techniques presented in this work, a viable pathway exists to realize larger devices with $cm^2$-scale active area and beyond.
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- 2023
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16. Counterexamples to the comparison principle in the special Lagrangian potential equation
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Brustad, Karl K.
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- 2024
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17. A Superconducting Nanowire Binary Shift Register
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Foster, Reed A., Castellani, Matteo, Buzzi, Alessandro, Medeiros, Owen, Colangelo, Marco, and Berggren, Karl K.
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Physics - Applied Physics - Abstract
We present a design for a superconducting nanowire binary shift register, which stores digital states in the form of circulating supercurrents in high-kinetic-inductance loops. Adjacent superconducting loops are connected with nanocryotrons, three terminal electrothermal switches, and fed with an alternating two-phase clock to synchronously transfer the digital state between the loops. A two-loop serial-input shift register was fabricated with thin-film NbN and achieved a bit error rate less than $10^{-4}$, operating at a maximum clock frequency of $83\,\mathrm{MHz}$ and in an out-of-plane magnetic field up to $6\,\mathrm{mT}$. A shift register based on this technology offers an integrated solution for low-power readout of superconducting nanowire single photon detector arrays, and is capable of interfacing directly with room-temperature electronics and operating unshielded in high magnetic field environments., Comment: The following article has been published in Applied Physics Letters issue 122. 10 pages, 3 figures
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- 2023
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18. The Infinity-Laplacian in Smooth Convex Domains and in a Square
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Brustad, Karl K., Lindgren, Erik, and Lindqvist, Peter
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Mathematics - Analysis of PDEs ,35J65, 35J94, 35P30, 49N60 - Abstract
We extend some theorems for the Infinity-Ground State and for the Infinity-Potential, known for convex polygons, to other domains in the plane, by applying Alexandroff's method to the curved boundary. A recent explicit solution disproves a conjecture.
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- 2023
19. Reduced ITO for Transparent Superconducting Electronics
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Batson, Emma, Colangelo, Marco, Simonaitis, John, Gebremeskel, Eyosias, Medeiros, Owen, Saravanapavanantham, Mayuran, Bulovic, Vladimir, Keathley, P. Donald, and Berggren, Karl K.
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Physics - Applied Physics ,Condensed Matter - Superconductivity - Abstract
Absorption of light in superconducting electronics is a major limitation on the quality of circuit architectures that integrate optical components with superconducting components. A 10 nm thick film of a typical superconducting material like niobium can absorb over half of any incident optical radiation. We propose instead using superconductors which are transparent to the wavelengths used elsewhere in the system. In this paper we investigated reduced indium tin oxide (ITO) as a potential transparent superconductor for electronics. We fabricated and characterized superconducting wires of reduced indium tin oxide. We also showed that a $\SI{10}{nm}$ thick film of the material would only absorb about 1 - 20\% of light between 500 - 1700 nm., Comment: 11 pages + 10 pages appendix, 5 figures + 5 figures appendix, submitting to IOP SUST
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- 2022
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20. A Nanocryotron Memory and Logic Family
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Buzzi, Alessandro, Castellani, Matteo, Foster, Reed A., Medeiros, Owen, Colangelo, Marco, and Berggren, Karl K.
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Physics - Applied Physics - Abstract
The development of superconducting electronics based on nanocryotrons has been limited so far to few-device circuits, in part due to the lack of standard and robust logic cells. Here, we introduce and experimentally demonstrate designs for a set of nanocryotron-based building blocks that can be configured and combined to implement memory and logic functions. The devices were fabricated by patterning a single superconducting layer of niobium nitride and measured in liquid helium on a wide range of operating points. The tests show $10^{-4}$ bit error rates with above $20\,\%$ margins up to $50\,$MHz and the possibility of operating under the effect of a perpendicular $36\,$mT magnetic field, with $30\,\%$ margins at $10\,$MHz. Additionally, we designed and measured an equivalent delay flip-flop made of two memory cells to show the possibility of combining multiple building blocks to make larger circuits. These blocks may constitute a solid foundation for the development of nanocryotron logic circuits and finite-state machines with potential applications in the integrated processing and control of superconducting nanowire single-photon detectors., Comment: Submitted for publication in the Applied Physics Letters special issue "Advances in Superconducting Logic", 8 pages, 5 figures
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- 2022
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21. AVATAR 2.0: next level communication systems for radiotherapy through face-to-face video, biofeedback, translation, and audiovisual immersion
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Joseph B. Schulz, Laszlo Zalavari, Paulina Gutkin, Alice Jiang, Yi-Peng Wang, Clinton Gibson, Aaron Garza, Karl K. Bush, Lei Wang, Sarah Susan Donaldson, Billy W. Loo, Susan M. Hiniker, and Lawrie Skinner
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pediatric radiotherapy ,anesthesia ,video immersion ,video distraction ,patient communication ,biofeedback ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
PurposeThis paper discusses an advanced version of our audiovisual-assisted therapeutic ambience in radiotherapy (AVATAR) radiolucent display systems designed for pediatric radiotherapy, enabling anesthesia-free treatments, video communication, and biofeedback. The scope of the AVATAR system is expanded here in two major ways: (i) through alternative mounting systems to accommodate a broader range of radiotherapy machines (specifically to fit robotic-arm and toroidal geometry photon radiotherapy and proton radiotherapy systems) and (ii) through additional hardware to provide video-calling, optimized audio for clear communication, and combined video inputs for biofeedback, translation, and other advanced functionalities.Methods and materialsBecause robustness requires strong parts and radio-transparency requires thin, light parts, three-dimensional printing was used to rapidly prototype hollow structures and to iteratively improve robustness. Two system designs were made: one that mounts superior and another that mounts inferior to the patient’s head. Radiation dose measurements and calculations were conducted to assess dose perturbations at surface and depth due to the screen.ResultsFor 6-MV volumetric modulated arc therapy (VMAT) plans, with and without the screen, the mean and maximum dose differences inside the planning target volume were 0.2% and 2.6% of the 200 cGy prescription, respectively. For a single static beam through the screen, the maximum measured excess surface dose was 13.4 ± 0.5%, and the largest measured dose attenuation at 5-cm water-equivalent depth was 2.1 ± 0.2%. These percentages are relative to the dose without the screen at those locations.ConclusionsThe radiolucent screen systems provided here are shown to give minimal dosimetric effects on megavoltage VMAT photon treatments. For static beams, however, surface dose effects should be considered when these beams pass through the thickest components of the screen. Design files are also provided.
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- 2024
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22. The Infinity-Potential in the Square
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Brustad, Karl K.
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Mathematics - Analysis of PDEs - Abstract
A representation formula for the solution of the $\infty$-Laplace equation is constructed in a punctured square, the prescribed boundary values being $u=0$ on the sides and $u=1$ at the centre. This so-called $\infty$-potential is obtained with a hodograph method. The heat equation is used and one of Jacobi's Theta functions appears. The formula disproves a conjecture., Comment: 24 pages, 4 figures
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- 2022
23. Single-photon detection using large-scale high-temperature MgB2 sensors at 20 K
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Ilya Charaev, Emma K. Batson, Sergey Cherednichenko, Kate Reidy, Vladimir Drakinskiy, Yang Yu, Samuel Lara-Avila, Joachim D. Thomsen, Marco Colangelo, Francesca Incalza, Konstantin Ilin, Andreas Schilling, and Karl K. Berggren
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Science - Abstract
Abstract Ultra-fast single-photon detectors with high current density and operating temperature can benefit space and ground applications, including quantum optical communication systems, lightweight cryogenics for space crafts, and medical use. Here we demonstrate magnesium diboride (MgB2) thin-film superconducting microwires capable of single-photon detection at 1.55 μm optical wavelength. We used helium ions to alter the properties of MgB2, resulting in microwire-based detectors exhibiting single-photon sensitivity across a broad temperature range of up to 20 K, and detection efficiency saturation for 1 μm wide microwires at 3.7 K. Linearity of detection rate vs incident power was preserved up to at least 100 Mcps. Despite the large active area of up to 400 × 400 μm2, the reset time was found to be as low as ~ 1 ns. Our research provides possibilities for breaking the operating temperature limit and maximum single-pixel count rate, expanding the detector area, and raises inquiries about the fundamental mechanisms of single-photon detection in high-critical-temperature superconductors.
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- 2024
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24. Free-electron-light interactions in nanophotonics
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Roques-Carmes, Charles, Kooi, Steven E., Yang, Yi, Rivera, Nicholas, Keathley, Phillip D., Joannopoulos, John D., Johnson, Steven G., Kaminer, Ido, Berggren, Karl K., and Soljačić, Marin
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Physics - Optics ,Physics - Applied Physics - Abstract
When impinging on optical structures or passing in their vicinity, free electrons can spontaneously emit electromagnetic radiation, a phenomenon generally known as cathodoluminescence. Free-electron radiation comes in many guises: Cherenkov, transition, and Smith-Purcell radiation, but also electron scintillation, commonly referred to as incoherent cathodoluminescence. While those effects have been at the heart of many fundamental discoveries and technological developments in high-energy physics in the past century, their recent demonstration in photonic and nanophotonic systems has attracted a lot of attention. Those developments arose from predictions that exploit nanophotonics for novel radiation regimes, now becoming accessible thanks to advances in nanofabrication. In general, the proper design of nanophotonic structures can enable shaping, control, and enhancement of free-electron radiation, for any of the above-mentioned effects. Free-electron radiation in nanophotonics opens the way to promising applications, such as widely-tunable integrated light sources from x-ray to THz frequencies, miniaturized particle accelerators, and highly sensitive high-energy particle detectors. Here, we review the emerging field of free-electron radiation in nanophotonics. We first present a general, unified framework to describe free-electron light-matter interaction in arbitrary nanophotonic systems. We then show how this framework sheds light on the physical underpinnings of many methods in the field used to control and enhance free-electron radiation. Namely, the framework points to the central role played by the photonic eigenmodes in controlling the output properties of free-electron radiation (e.g., frequency, directionality, and polarization). [... see full abstract in paper], Comment: 34 pages; 9 figures
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- 2022
25. Counterexamples to the comparison principle in the special Lagrangian potential equation
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Brustad, Karl K.
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Mathematics - Analysis of PDEs - Abstract
For each $k = 0,\dots,n$ we construct a continuous phase $f_k$, with $f_k(0) = (n-2k)\frac{\pi}{2}$, and viscosity sub- and supersolutions $v_k$, $u_k$, of the elliptic PDE $\sum_{i=1}^n \arctan(\lambda_i(D^2 w)) = f_k(x)$ such that $v_k-u_k$ has an isolated maximum at the origin. It has been an open question whether the comparison principle would hold in this second order equation for arbitrary continuous phases $f\colon\Omega\to (-n\pi/2,n\pi/2)$. Our examples show it does not.
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- 2022
26. Reversible Tuning of Superconductivity in Ion-Gated NbN Ultrathin Films by Self-Encapsulation with a High-$\kappa$ Dielectric Layer
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Piatti, Erik, Colangelo, Marco, Bartoli, Mattia, Medeiros, Owen, Gonnelli, Renato S., Berggren, Karl K., and Daghero, Dario
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Condensed Matter - Superconductivity ,Condensed Matter - Mesoscale and Nanoscale Physics ,Condensed Matter - Materials Science - Abstract
Ionic gating is a powerful technique for tuning the physical properties of a material via electric field-induced charge doping, but is prone to introduce extrinsic disorder and undesired electrochemical modifications in the gated material beyond pure electrostatics. Conversely, reversible, volatile and electrostatic modulation is pivotal in the reliable design and operation of novel device concepts enabled by the ultrahigh induced charge densities attainable via ionic gating. Here we demonstrate a simple and effective method to achieve reversible and volatile gating of surface-sensitive ultrathin niobium nitride films via controlled oxidation of their surface. The resulting niobium oxide encapsulation layer exhibits a capacitance comparable to that of non-encapsulated ionic transistors, withstands gate voltages beyond the electrochemical stability window of the gate electrolyte, and enables a fully-reversible tunability of both the normal-state resistivity and the superconducting transition temperature of the encapsulated films. Our approach should be transferable to other materials and device geometries where more standard encapsulation techniques are not readily applicable., Comment: Main text: 11 pages, 6 figures; Supplementary: 8 pages, 6 figures
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- 2022
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27. Photon counting from the vacuum ultraviolet to the short wavelength infrared using semiconductor and superconducting technologies
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Asaadi, Jonathan, Baxter, Dan, Berggren, Karl K., Braga, Davide, Charlebois, Serge A., Chang, Clarence, Dragone, Angelo, Drlica-Wagner, Alex, Escobar, Carlos O., Estrada, Juan, Fahim, Farah, Febbraro, Michael, Moroni, Guillermo Fernandez, Holland, Stephen, Hossbach, Todd, Koppell, Stewart, Leitz, Christopher, Magnoni, Agustina, Mazin, Benjamin A., Pratte, Jean-François, Rauscher, Bernie, Rodrigues, Dario, Shen, Lingjia, Sofo-Haro, Miguel, Tiffenberg, Javier, Turner, Joshua, Rota, Lorenzo, Kenney, Christopher J., Vachon, Frédéric, and Wang, Gensheng
- Subjects
Physics - Instrumentation and Detectors ,High Energy Physics - Experiment - Abstract
In the last decade, several photon counting technologies have been developed opening a new window for experiments in the low photon number regime. Several ongoing and future projects in HEP benefit from these developments, which will also have a large impact outside HEP. During the next decade there is a clear technological opportunity to fully develop these sensors and produce a large impact in HEP. In this white paper we discuss the need for photon counting technologies in future projects, and present some technological opportunities to address those needs.
- Published
- 2022
28. American Society for Gastrointestinal Endoscopy best practice statements on the sharing of endoscopic images and videos on social media
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Chan, Walter W., Advani, Rashmi R., Bilal, Mohammad, Charabaty, Aline, Kwok, Karl K., Laster, Janese S., Perelman, Alexander, Siddique, Shazia M., Trieu, Judy, Umoren, Mfoniso D., and Chiang, Austin L.
- Published
- 2024
- Full Text
- View/download PDF
29. Hepatoprotective potential of alpha-lipoic acid against gliclazide-induced liver injury in high-glucose-exposed human liver cells and experimental type 2 diabetic rats
- Author
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Dugbartey, George J., Atule, Stephen, Alornyo, Karl K., and Adams, Ismaila
- Published
- 2024
- Full Text
- View/download PDF
30. Electron Emission Regimes of Planar Nano Vacuum Emitters
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Turchetti, Marco, Yang, Yujia, Bionta, Mina R., Nardi, Alberto, Daniel, Luca, Berggren, Karl K., and Keathley, Phillip D.
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Physics - Applied Physics - Abstract
Recent advancements in nanofabrication have enabled the creation of vacuum electronic devices with nanoscale free space gaps. These nanoelectronic devices promise the benefits of cold-field emission and transport through free-space, such as high nonlinearity and relative insensitivity to temperature and ionizing radiation, all the while drastically reducing the footprint, increasing the operating bandwidth and reducing the power consumption of each device. Furthermore, planarized vacuum nanoelectronics could easily be integrated at scale similar to typical micro and nanoscale semiconductor electronics. However, the interplay between different electron emission mechanisms from these devices are not well understood, and inconsistencies with pure Fowler-Nordheim emission have been noted by others. In this work, we systematically study the current-voltage characteristics of planar vacuum nano-diodes having few-nanometer radii of curvature and free-space gaps between the emitter and collector. By investigating the current-voltage characteristics of nearly identical diodes fabricated from two different materials and under various environmental conditions, such as temperature and atmospheric pressure, we were able to clearly isolate three distinct emission regimes within a single device: Schottky, Fowler-Nordheim, and saturation. Our work will enable robust and accurate modeling of vacuum nanoelectronics which will be critical for future applications requiring high-speed and low-power electronics capable of operation in extreme conditions.
- Published
- 2022
- Full Text
- View/download PDF
31. Improved heralded single-photon source with a photon-number-resolving superconducting nanowire detector
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Davis, Samantha I., Mueller, Andrew, Valivarthi, Raju, Lauk, Nikolai, Narvaez, Lautaro, Korzh, Boris, Beyer, Andrew D., Colangelo, Marco, Berggren, Karl K., Shaw, Matthew D., Sinclair, Neil, and Spiropulu, Maria
- Subjects
Quantum Physics ,Physics - Optics - Abstract
Deterministic generation of single photons is essential for many quantum information technologies. A bulk optical nonlinearity emitting a photon pair, where the measurement of one of the photons heralds the presence of the other, is commonly used with the caveat that the single-photon emission rate is constrained due to a trade-off between multiphoton events and pair emission rate. Using an efficient and low noise photon-number-resolving superconducting nanowire detector we herald, in real time, a single photon at telecommunication wavelength. We perform a second-order photon correlation $g^{2}(0)$ measurement of the signal mode conditioned on the measured photon number of the idler mode for various pump powers and demonstrate an improvement of a heralded single-photon source. We develop an analytical model using a phase-space formalism that encompasses all multiphoton effects and relevant imperfections, such as loss and multiple Schmidt modes. We perform a maximum-likelihood fit to test the agreement of the model to the data and extract the best-fit mean photon number $\mu$ of the pair source for each pump power. A maximum reduction of $0.118 \pm 0.012$ in the photon $g^{2}(0)$ correlation function at $\mu = 0.327 \pm 0.007$ is obtained, indicating a strong suppression of multiphoton emissions. For a fixed $g^{2}(0) = 7e-3$, we increase the single pair generation probability by 25%. Our experiment, built using fiber-coupled and off-the-shelf components, delineates a path to engineering ideal sources of single photons., Comment: Model and analysis integrated into main text. Corrected equations. 17 pages, 11 figures
- Published
- 2021
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32. A Superconducting Nanowire-based Architecture for Neuromorphic Computing
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Lombo, Andres E., Lares, Jesus E., Castellani, Matteo, Chou, Chi-Ning, Lynch, Nancy, and Berggren, Karl K.
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Computer Science - Emerging Technologies ,Condensed Matter - Superconductivity ,Physics - Applied Physics - Abstract
Neuromorphic computing is poised to further the success of software-based neural networks by utilizing improved customized hardware. However, the translation of neuromorphic algorithms to hardware specifications is a problem that has been seldom explored. Building superconducting neuromorphic systems requires extensive expertise in both superconducting physics and theoretical neuroscience. In this work, we aim to bridge this gap by presenting a tool and methodology to translate algorithmic parameters into circuit specifications. We first show the correspondence between theoretical neuroscience models and the dynamics of our circuit topologies. We then apply this tool to solve linear systems by implementing a spiking neural network with our superconducting nanowire-based hardware., Comment: 29 pages, 10 figures
- Published
- 2021
33. Broadband solenoidal haloscope for terahertz axion detection
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Liu, Jesse, Dona, Kristin, Hoshino, Gabe, Knirck, Stefan, Kurinsky, Noah, Malaker, Matthew, Miller, David W., Sonnenschein, Andrew, Awida, Mohamed H., Barry, Peter S., Berggren, Karl K., Bowring, Daniel, Carosi, Gianpaolo, Chang, Clarence, Chou, Aaron, Khatiwada, Rakshya, Lewis, Samantha, Li, Juliang, Nam, Sae Woo, Noroozian, Omid, and Zhou, Tony X.
- Subjects
Physics - Instrumentation and Detectors ,Astrophysics - Instrumentation and Methods for Astrophysics ,High Energy Physics - Experiment ,High Energy Physics - Phenomenology - Abstract
We introduce the Broadband Reflector Experiment for Axion Detection (BREAD) conceptual design and science program. This haloscope plans to search for bosonic dark matter across the [10$^{-3}$, 1] eV ([0.24, 240] THz) mass range. BREAD proposes a cylindrical metal barrel to convert dark matter into photons, which a novel parabolic reflector design focuses onto a photosensor. This unique geometry enables enclosure in standard cryostats and high-field solenoids, overcoming limitations of current dish antennas. A pilot 0.7 m$^{2}$ barrel experiment planned at Fermilab is projected to surpass existing dark photon coupling constraints by over a decade with one-day runtime. Axion sensitivity requires $<10^{-20}$ W/$\sqrt{\textrm{Hz}}$ sensor noise equivalent power with a 10 T solenoid and 10 m$^{2}$ barrel. We project BREAD sensitivity for various sensor technologies and discuss future prospects., Comment: 5 pages, 2 figures + references and appendices, v2 matches journal version
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- 2021
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34. Secondary Electron Count Imaging in SEM
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Agarwal, Akshay, Simonaitis, John, Goyal, Vivek K., and Berggren, Karl K.
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Physics - Instrumentation and Detectors ,Physics - Applied Physics ,Quantum Physics - Abstract
Scanning electron microscopy (SEM) is a versatile technique used to image samples at the nanoscale. Conventional imaging by this technique relies on finding the average intensity of the signal generated on a detector by secondary electrons (SEs) emitted from the sample and is subject to noise due to variations in the voltage signal from the detector. This noise can result in degradation of the SEM image quality for a given imaging dose. SE count imaging, which uses the direct count of SEs detected from the sample instead of the average signal intensity, would overcome this limitation and lead to improvement in SEM image quality. In this paper, we implement an SE count imaging scheme by synchronously outcoupling the detector and beam scan signals from the microscope and using custom code to count detected SEs. We demonstrate a ~30% increase in the image signal-to-noise-ratio due to SE counting compared to conventional imaging. The only external hardware requirement for this imaging scheme is an oscilloscope fast enough to accurately sample the detector signal for SE counting, making the scheme easily implementable on any SEM.
- Published
- 2021
35. 50 Ohm Transmission Lines with Extreme Wavelength Compression Based on Superconducting Nanowires on High-Permittivity Substrates
- Author
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Santavicca, Daniel F., Colangelo, Marco, Eagle, Carleigh R., Warusawithana, Maitri P., and Berggren, Karl K.
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Condensed Matter - Superconductivity ,Condensed Matter - Mesoscale and Nanoscale Physics ,Physics - Applied Physics - Abstract
We demonstrate impedance-matched low-loss transmission lines with a signal wavelength more than 150 times smaller than the free space wavelength using superconducting nanowires on high permittivity substrates. A niobium nitride thin film is patterned in a coplanar waveguide (CPW) transmission line geometry on a bilayer substrate consisting of 100 nm of epitaxial strontium titanate on high-resitivity silicon. The use of strontium titanate on silicon enables wafer-scale fabrication and maximizes process compatibility. It also makes it possible to realize a $50$ $\Omega$ characteristic impedance across a wide range of CPW widths, from the nanoscale to the macroscale. We fabricated and characterized an approximately $50$ $\Omega$ CPW device with two half-wave stub resonators. Comparing the measured transmission coefficient to numerical simulations, we determine that the strontium titanate film has a dielectric constant of $1.1 \times 10^3$ and a loss tangent of not more than 0.009. To facilitate the design of distributed microwave devices based on this type of material system, we describe an analytical model of the CPW properties that gives good agreement with both measurements and simulations.
- Published
- 2021
- Full Text
- View/download PDF
36. New constraints on dark matter from superconducting nanowires
- Author
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Hochberg, Yonit, Lehmann, Benjamin V., Charaev, Ilya, Chiles, Jeff, Colangelo, Marco, Nam, Sae Woo, and Berggren, Karl K.
- Subjects
High Energy Physics - Phenomenology ,Condensed Matter - Superconductivity ,High Energy Physics - Experiment ,Quantum Physics - Abstract
Superconducting nanowires, a mature technology originally developed for quantum sensing, can be used as a target and sensor with which to search for dark matter interactions with electrons. Here we report on a 180-hour measurement of a tungsten silicide superconducting nanowire device with a mass of 4.3 nanograms. We use this to place new constraints on dark matter--electron interactions, including the strongest terrestrial constraints to date on sub-MeV (sub-eV) dark matter that interacts with electrons via scattering (absorption) processes., Comment: 5 pages + appendices, 5 figures. Matched published version
- Published
- 2021
- Full Text
- View/download PDF
37. New Constraints on Dark Photon Dark Matter with Superconducting Nanowire Detectors in an Optical Haloscope
- Author
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Chiles, Jeff, Charaev, Ilya, Lasenby, Robert, Baryakhtar, Masha, Huang, Junwu, Roshko, Alexana, Burton, George, Colangelo, Marco, Van Tilburg, Ken, Arvanitaki, Asimina, Nam, Sae Woo, and Berggren, Karl K.
- Subjects
High Energy Physics - Experiment ,Astrophysics - Cosmology and Nongalactic Astrophysics ,High Energy Physics - Phenomenology ,Physics - Instrumentation and Detectors - Abstract
Uncovering the nature of dark matter is one of the most important goals of particle physics. Light bosonic particles, such as the dark photon, are well-motivated candidates: they are generally long-lived, weakly-interacting, and naturally produced in the early universe. In this work, we report on LAMPOST (Light $A'$ Multilayer Periodic Optical SNSPD Target), a proof-of-concept experiment searching for dark photon dark matter in the eV mass range, via coherent absorption in a multi-layer dielectric haloscope. Using a superconducting nanowire single-photon detector (SNSPD), we achieve efficient photon detection with a dark count rate (DCR) of $\sim 6\times10^{-6}$ counts/s. We find no evidence for dark photon dark matter in the mass range of $\sim 0.7$-$0.8$ eV with kinetic mixing $\epsilon \gtrsim 10^{-12}$, improving existing limits in $\epsilon$ by up to a factor of two. With future improvements to SNSPDs, our architecture could probe significant new parameter space for dark photon and axion dark matter in the meV to 10 eV mass range.
- Published
- 2021
- Full Text
- View/download PDF
38. PHz Electronic Device Design and Simulation for Waveguide-Integrated Carrier-Envelope Phase Detection
- Author
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Mor, Dario Cattozzo, Yang, Yujia, Ritzkowsky, Felix, Kärtner, Franz X., Berggren, Karl K., Singh, Neetesh Kumar, and Keathley, Phillip D.
- Subjects
Physics - Optics ,Physics - Instrumentation and Detectors - Abstract
Carrier-envelope phase (CEP) detection of ultrashort optical pulses and low-energy waveform field sampling have recently been demonstrated using direct time-domain methods that exploit optical-field photoemission from plasmonic nanoantennas. These devices make for compact and integratable solid-state detectors operating at optical frequency that work in ambient conditions and require minute pulse energies (picojoule-level). Applications include frequency-comb stabilization, visible to near-infrared time-domain spectroscopy, compact tools for attosecond science and metrology and, due to the high electronic switching speeds, petahertz-scale information processing. However, these devices have been driven by free-space optical waveforms and their implementation within integrated photonic platforms has yet to be demonstrated. In this work, we design and simulate fully-integrated plasmonic bow-tie nanoantennas coupled to a Si$_3$N$_4$-core waveguide for CEP detection. We find that when coupled to realistic on-chip, few-cycle supercontinuum sources, these devices are suitable for direct time-domain CEP detection within integrated photonic platforms. We estimate a signal-to-noise ratio of 30 dB at 50 kHz resolution bandwidth. We address technical details, such as the tuning of the nanoantennas plasmonic resonance and the waveform's CEP slippage in the waveguide. Moreover, we evaluate power losses due to absorption and scattering and we study the device sensitivity to pulse duration and pulse peak field intensity. Our results provide the basis for future design and fabrication of time-domain CEP detectors and allow for the development of fully-integrated attosecond science applications, frequency-comb stabilization and light-wave-based PHz electronics., Comment: 13 pages, 9 figures, submitted to Journal of Lightwave Technology
- Published
- 2021
- Full Text
- View/download PDF
39. Multi-scale signaling and tumor evolution in high-grade gliomas
- Author
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Liu, Jingxian, Cao, Song, Imbach, Kathleen J., Gritsenko, Marina A., Lih, Tung-Shing M., Kyle, Jennifer E., Yaron-Barir, Tomer M., Binder, Zev A., Li, Yize, Strunilin, Ilya, Wang, Yi-Ting, Tsai, Chia-Feng, Ma, Weiping, Chen, Lijun, Clark, Natalie M., Shinkle, Andrew, Naser Al Deen, Nataly, Caravan, Wagma, Houston, Andrew, Simin, Faria Anjum, Wyczalkowski, Matthew A., Wang, Liang-Bo, Storrs, Erik, Chen, Siqi, Illindala, Ritvik, Li, Yuping D., Jayasinghe, Reyka G., Rykunov, Dmitry, Cottingham, Sandra L., Chu, Rosalie K., Weitz, Karl K., Moore, Ronald J., Sagendorf, Tyler, Petyuk, Vladislav A., Nestor, Michael, Bramer, Lisa M., Stratton, Kelly G., Schepmoes, Athena A., Couvillion, Sneha P., Eder, Josie, Kim, Young-Mo, Gao, Yuqian, Fillmore, Thomas L., Zhao, Rui, Monroe, Matthew E., Southard-Smith, Austin N., Li, Yang E., Jui-Hsien Lu, Rita, Johnson, Jared L., Wiznerowicz, Maciej, Hostetter, Galen, Newton, Chelsea J., Ketchum, Karen A., Thangudu, Ratna R., Barnholtz-Sloan, Jill S., Wang, Pei, Fenyö, David, An, Eunkyung, Thiagarajan, Mathangi, Robles, Ana I., Mani, D.R., Smith, Richard D., Porta-Pardo, Eduard, Cantley, Lewis C., Iavarone, Antonio, Chen, Feng, Mesri, Mehdi, Nasrallah, MacLean P., Zhang, Hui, Resnick, Adam C., Chheda, Milan G., Rodland, Karin D., Liu, Tao, and Ding, Li
- Published
- 2024
- Full Text
- View/download PDF
40. Elucidating regulatory processes of intense physical activity by multi-omics analysis
- Author
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Nakayasu, Ernesto S., Gritsenko, Marina A., Kim, Young-Mo, Kyle, Jennifer E., Stratton, Kelly G., Nicora, Carrie D., Munoz, Nathalie, Navarro, Kathleen M., Claborne, Daniel, Gao, Yuqian, Weitz, Karl K., Paurus, Vanessa L., Bloodsworth, Kent J., Allen, Kelsey A., Bramer, Lisa M., Montes, Fernando, Clark, Kathleen A., Tietje, Grant, Teeguarden, Justin, and Burnum-Johnson, Kristin E.
- Published
- 2023
- Full Text
- View/download PDF
41. Impedance-matched differential superconducting nanowire detectors
- Author
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Colangelo, Marco, Korzh, Boris, Allmaras, Jason P., Beyer, Andrew D., Mueller, Andrew S., Briggs, Ryan M., Bumble, Bruce, Runyan, Marcus, Stevens, Martin J., McCaughan, Adam N., Zhu, Di, Smith, Stephen, Becker, Wolfgang, Narváez, Lautaro, Bienfang, Joshua C., Frasca, Simone, Velasco, Angel E., Peña, Cristián H., Ramirez, Edward E., Walter, Alexander B., Schmidt, Ekkehart, Wollman, Emma E., Spiropulu, Maria, Mirin, Richard, Nam, Sae Woo, Berggren, Karl K., and Shaw, Matthew D.
- Subjects
Physics - Applied Physics - Abstract
Superconducting nanowire single-photon detectors (SNSPDs) are the highest performing photon-counting technology in the near-infrared (NIR). Due to delay-line effects, large area SNSPDs typically trade-off timing resolution and detection efficiency. Here, we introduce a detector design based on transmission line engineering and differential readout for device-level signal conditioning, enabling a high system detection efficiency and a low detector jitter, simultaneously. To make our differential detectors compatible with single-ended time taggers, we also engineer analog differential-to-single-ended readout electronics, with minimal impact on the system timing resolution. Our niobium nitride differential SNSPDs achieve $47.3\,\% \pm 2.4\,\%$ system detection efficiency and sub-$10\,\mathrm{ps}$ system jitter at $775\,\mathrm{nm}$, while at $1550\,\mathrm{nm}$ they achieve $71.1\,\% \pm 3.7\,\%$ system detection efficiency and $13.1\,\mathrm{ps} \pm 0.4\,\mathrm{ps}$ system jitter. These detectors also achieve sub-100 ps timing response at one one-hundredth maximum level, $30.7\,\mathrm{ps} \pm 0.4\,\mathrm{ps}$ at $775\,\mathrm{nm}$ and $47.6\,\mathrm{ps} \pm 0.4\,\mathrm{ps}$ at $1550\,\mathrm{nm}$, enabling time-correlated single-photon counting with high dynamic range response functions. Furthermore, thanks to the differential impedance-matched design, our detectors exhibit delay-line imaging capabilities and photon-number resolution. The properties and high-performance metrics achieved by our system make it a versatile photon-detection solution for many scientific applications.
- Published
- 2021
42. Sobolev gradients of viscosity supersolutions
- Author
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Brustad, Karl K.
- Subjects
Mathematics - Analysis of PDEs - Abstract
We investigate which elliptic PDEs that have the property that every viscosity supersolution is $W^{1,q}_{loc}(\Omega)$, $\Omega\subseteq\mathbb{R}^n$. The asymptotic cone of the operator's sublevel set seems to be essential. It turns out that much can be said if we know how this cone compares to the sublevel set of a certain minimal operator associated with the exponent $q$., Comment: 20 pages, 1 figure
- Published
- 2021
43. Elucidating regulatory processes of intense physical activity by multi-omics analysis
- Author
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Ernesto S. Nakayasu, Marina A. Gritsenko, Young-Mo Kim, Jennifer E. Kyle, Kelly G. Stratton, Carrie D. Nicora, Nathalie Munoz, Kathleen M. Navarro, Daniel Claborne, Yuqian Gao, Karl K. Weitz, Vanessa L. Paurus, Kent J. Bloodsworth, Kelsey A. Allen, Lisa M. Bramer, Fernando Montes, Kathleen A. Clark, Grant Tietje, Justin Teeguarden, and Kristin E. Burnum-Johnson
- Subjects
Multi-omics analysis ,Intense exercise ,Human performance ,Biofluids ,Metabolism ,Immunity ,Medicine (General) ,R5-920 ,Military Science - Abstract
Abstract Background Physiological and biochemical processes across tissues of the body are regulated in response to the high demands of intense physical activity in several occupations, such as firefighting, law enforcement, military, and sports. A better understanding of such processes can ultimately help improve human performance and prevent illnesses in the work environment. Methods To study regulatory processes in intense physical activity simulating real-life conditions, we performed a multi-omics analysis of three biofluids (blood plasma, urine, and saliva) collected from 11 wildland firefighters before and after a 45 min, intense exercise regimen. Omics profiles post- versus pre-exercise were compared by Student’s t-test followed by pathway analysis and comparison between the different omics modalities. Results Our multi-omics analysis identified and quantified 3835 proteins, 730 lipids and 182 metabolites combining the 3 different types of samples. The blood plasma analysis revealed signatures of tissue damage and acute repair response accompanied by enhanced carbon metabolism to meet energy demands. The urine analysis showed a strong, concomitant regulation of 6 out of 8 identified proteins from the renin-angiotensin system supporting increased excretion of catabolites, reabsorption of nutrients and maintenance of fluid balance. In saliva, we observed a decrease in 3 pro-inflammatory cytokines and an increase in 8 antimicrobial peptides. A systematic literature review identified 6 papers that support an altered susceptibility to respiratory infection. Conclusion This study shows simultaneous regulatory signatures in biofluids indicative of homeostatic maintenance during intense physical activity with possible effects on increased infection susceptibility, suggesting that caution against respiratory diseases could benefit workers on highly physical demanding jobs.
- Published
- 2023
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- View/download PDF
44. The infinity-Laplacian in smooth convex domains and in a square
- Author
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Karl K. Brustad, Erik Lindgren, and Peter Lindqvist
- Subjects
the infinity-laplace operator ,nonlinear eigenvalue problem ,convex plane domains ,gradient flow ,alexandroff's moving plane ,Applied mathematics. Quantitative methods ,T57-57.97 - Abstract
We extend some theorems for the infinity-ground state and for the infinity-potential, known for convex polygons, to other domains in the plane, by applying Alexandroff's method to the curved boundary. A recent explicit solution disproves a conjecture.
- Published
- 2023
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- View/download PDF
45. Child and family factors associated with positive outcomes among youth born extremely preterm
- Author
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Emmanuel, Crisma, Yi, Joe X., Joseph, Robert M., Kuban, Karl K. C., Knafl, Kathy A., Docherty, Sharron L., Hodges, Eric A., Fry, Rebecca C., O’Shea, T. Michael, and Santos, Jr., Hudson P.
- Published
- 2023
- Full Text
- View/download PDF
46. Parallel implementations of randomized vector algorithm for solving large systems of linear equations
- Author
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Sabelfeld, Karl K., Kireev, Sergey, and Kireeva, Anastasiya
- Published
- 2023
- Full Text
- View/download PDF
47. Physical properties of amorphous molybdenum silicide films for single photon detectors
- Author
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Zhang, Xiaofu, Charaev, Ilya, Liu, Huanlong, Zhou, Tony X., Zhu, Dong, Berggren, Karl K., and Schilling, Andreas
- Subjects
Condensed Matter - Superconductivity - Abstract
We systematically investigated the physical properties of amorphous Mo$_{\rm x}$Si$_{1-x}$ films deposited by the magnetron co-sputtering technique. The critical temperature $T_C$ of Mo$_{\rm x}$ Si$_{1-x}$ films increases gradually with the stoichiometry x, and the highest $T_C$=7.9 K was found in Mo$_{\rm 0.83}$ Si$_{0.17}$. Beyond $x$=0.83, preformed Cooper pairs and superconducting domains persist in the films, despite the superconducting state with perfect zero-resistivity is absent. The thick films of Mo$_{\rm 0.83}$ Si$_{0.17}$ show surprising degradation in which the onset of zero-resistivity is suppressed below 2 K. The thin Mo$_{\rm 0.83}$ Si$_{0.17}$ films, however, reveal robust superconductivity even with thickness d$\leq$1 nm. We also characterized wide microwires based on the 2 nm thin Mo$_{\rm 0.8}$ Si$_{0.2}$ films with widths 40 and 60 $\mu$m, which show single-photon sensitivity at 780 nm and 1550 nm wavelength
- Published
- 2021
- Full Text
- View/download PDF
48. Nanoantenna Design for Enhanced Carrier-Envelope-Phase Sensitivity
- Author
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Buckley, Drew, Yang, Yujia, Yang-Keathley, Yugu, Berggren, Karl K., and Keathley, Phillip D.
- Subjects
Physics - Optics ,Condensed Matter - Mesoscale and Nanoscale Physics - Abstract
Optical-field emission from nanostructured solids such as subwavelength nanoantennas can be leveraged to create sub-femtosecond, PHz-scale electronics for optical-field detection. One application that is of particular interest is the detection of an incident optical pulse's carrier-envelope phase. Such carrier-envelope-phase detection requires few-cycle, broadband optical excitation where the resonant properties of the nanoantenna can strongly alter the response of the near field in time. Little quantitative investigation has been performed to understand how the geometry and resonant properties of the antennae should be tuned to enhance the carrier-envelope phase sensitivity and signal to noise ratio. Here we examine how the geometry and resonance frequency of planar plasmonic nanoantennas can be engineered for enhancing the emitted carrier-envelope-phase-sensitive photocurrent when driven by a few-cycle optical pulse. We find that with the simple addition of curved sidewalls leading to the apex, and proper tuning of the resonance wavelength, the net CEP-sensitive current per nanoantenna can be improved by $5$-$10\times$, and the signal-to-noise-ratio by $50$-$100\times$ relative to simple triangular antennas operated on resonance. Our findings will inform the next generation of nanoantenna designs for emerging applications in ultrafast photoelectron metrology and petahertz electronics.
- Published
- 2021
- Full Text
- View/download PDF
49. Author Correction: Genomic and epigenomic mapping of leptin-responsive neuronal populations involved in body weight regulation
- Author
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Inoue, Fumitaka, Eckalbar, Walter L., Wang, Yi, Murphy, Karl K., Matharu, Navneet, Vaisse, Christian, and Ahituv, Nadav
- Published
- 2024
- Full Text
- View/download PDF
50. Precise, Sub-Nanosecond, and High-Voltage Switching of Complex Loads Enabled by Gallium Nitride Electronics
- Author
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Simonaitis, John W., Slayton, Benjamin, Yang-Keathley, Yugu, Keathley, Phillip D., and Berggren, Karl K.
- Subjects
Physics - Instrumentation and Detectors ,Physics - Applied Physics - Abstract
In this work, we report the use of commercial Gallium Nitride (GaN) power electronics to precisely switch complex distributed loads, such as electron lenses and deflectors, without impedance matching. Depending on the chosen GaN field effect transistor (GaNFET) and driver, these GaN pulsers are capable of generating pulses ranging from 100 - 650 V and 5 - 60 A in 0.25 - 8 ns using simple designs with easy control, few-nanosecond propagation delays, and MHz repetition rates. We experimentally demonstrate a simple 250 ps, 100 V pulser measured by a directly coupled 2 GHz oscilloscope. By introducing resistive dampening, we can eliminate ringing to allow for precise 100 V transitions that complete a -10 V to -90 V transition in 1.5 ns, limited primarily by the inductance of the oscilloscope measurement path. The performance of the pulser attached to various load structures is simulated, demonstrating the possibility of even faster switching of internal fields in these loads. These circuits also have 0.25 cm$\mathrm{^2}$ active regions and <1 W power dissipation, enabling their integration into a wide variety of environments and apparatus. The proximity of the GaNFETs to the load due to this integration minimizes parasitic quantities that slow switching as well as remove the need to match from 50 ${\Omega}$ lines by allowing for a lumped element approximation small loads. We expect these GaN pulsers to have broad application in fields such as optics, nuclear sciences, charged particle optics, and atomic physics that require nanosecond, high-voltage transitions., Comment: 34 pages, 14 figures
- Published
- 2021
- Full Text
- View/download PDF
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