41 results on '"Karar, Mohamed Esmail"'
Search Results
2. Automated classification of urine biomarkers to diagnose pancreatic cancer using 1-D convolutional neural networks
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Karar, Mohamed Esmail, El-Fishawy, Nawal, and Radad, Marwa
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- 2023
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3. A Pilot Study of Smart Agricultural Irrigation using Unmanned Aerial Vehicles and IoT-Based Cloud System
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Karar, Mohamed Esmail, Alotaibi, Faris, Rasheed, Abdullah AL, and Reyad, Omar
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Electrical Engineering and Systems Science - Systems and Control ,Electrical Engineering and Systems Science - Signal Processing - Abstract
This article introduces a new mobile-based application of modern information and communication technology in agriculture based on Internet of Things (IoT), embedded systems and an unmanned aerial vehicle (UAV). The proposed agricultural monitoring system was designed and implemented using Arduino microcontroller boards, Wi-Fi modules, water pumps and electronic environmental sensors, namely temperature, humidity and soil moisture. The role of UAV in this study is to collect these environmental data from different regions of the farm. Then, the quantity of water irrigation is automatically computed for each region in the cloud. Moreover, the developed system can monitor the farm conditions including the water requirements remotely on Android mobile application to guide the farmers. The results of this study demonstrated that our proposed IoT-based embedded system can be effective to avoid unnecessary and wasted water irrigation within the framework of smart agriculture., Comment: 11 pages, 9 figures
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- 2021
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4. COVIDX-Net: A Framework of Deep Learning Classifiers to Diagnose COVID-19 in X-Ray Images
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Hemdan, Ezz El-Din, Shouman, Marwa A., and Karar, Mohamed Esmail
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Electrical Engineering and Systems Science - Image and Video Processing ,Computer Science - Computer Vision and Pattern Recognition ,Computer Science - Machine Learning - Abstract
Background and Purpose: Coronaviruses (CoV) are perilous viruses that may cause Severe Acute Respiratory Syndrome (SARS-CoV), Middle East Respiratory Syndrome (MERS-CoV). The novel 2019 Coronavirus disease (COVID-19) was discovered as a novel disease pneumonia in the city of Wuhan, China at the end of 2019. Now, it becomes a Coronavirus outbreak around the world, the number of infected people and deaths are increasing rapidly every day according to the updated reports of the World Health Organization (WHO). Therefore, the aim of this article is to introduce a new deep learning framework; namely COVIDX-Net to assist radiologists to automatically diagnose COVID-19 in X-ray images. Materials and Methods: Due to the lack of public COVID-19 datasets, the study is validated on 50 Chest X-ray images with 25 confirmed positive COVID-19 cases. The COVIDX-Net includes seven different architectures of deep convolutional neural network models, such as modified Visual Geometry Group Network (VGG19) and the second version of Google MobileNet. Each deep neural network model is able to analyze the normalized intensities of the X-ray image to classify the patient status either negative or positive COVID-19 case. Results: Experiments and evaluation of the COVIDX-Net have been successfully done based on 80-20% of X-ray images for the model training and testing phases, respectively. The VGG19 and Dense Convolutional Network (DenseNet) models showed a good and similar performance of automated COVID-19 classification with f1-scores of 0.89 and 0.91 for normal and COVID-19, respectively. Conclusions: This study demonstrated the useful application of deep learning models to classify COVID-19 in X-ray images based on the proposed COVIDX-Net framework. Clinical studies are the next milestone of this research work., Comment: 14 pages, 5 figures, 3 tables
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- 2020
5. Smart IoMT-based segmentation of coronavirus infections using lung CT scans
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Karar, Mohamed Esmail, Khan, Z. Faizal, Alshahrani, Hussain, and Reyad, Omar
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- 2023
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6. Computer-assisted lung diseases detection from pediatric chest radiography using long short-term memory networks
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Shouman, Marwa A., El-Fiky, Azza, Hamada, Salwa, El-Sayed, Ayman, and Karar, Mohamed Esmail
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- 2022
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7. A new mobile application of agricultural pests recognition using deep learning in cloud computing system
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Karar, Mohamed Esmail, Alsunaydi, Fahad, Albusaymi, Sultan, and Alotaibi, Sultan
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- 2021
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8. Secure CT-Image Encryption for COVID-19 Infections Using HBBS-Based Multiple Key-Streams
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Reyad, Omar and Karar, Mohamed Esmail
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- 2021
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9. A Practical Study of Intelligent Image-Based Mobile Robot for Tracking Colored Objects.
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Alymani, Mofadal, Karar, Mohamed Esmail, and Shehata, Hazem Ibrahim
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ADAPTIVE fuzzy control ,REAL-time control ,FUZZY control systems ,AUTONOMOUS robots ,ARTIFICIAL intelligence ,MOBILE robots ,OBJECT tracking (Computer vision) ,ADAPTIVE control systems - Abstract
Object tracking is one of the major tasks for mobile robots in many real-world applications. Also, artificial intelligence and automatic control techniques play an important role in enhancing the performance of mobile robot navigation. In contrast to previous simulation studies, this paper presents a new intelligent mobile robot for accomplishing multi-tasks by tracking red-green-blue (RGB) colored objects in a real experimental field. Moreover, a practical smart controller is developed based on adaptive fuzzy logic and custom proportional-integral-derivative (PID) schemes to achieve accurate tracking results, considering robot command delay and tolerance errors. The design of developed controllers implies some motion rules to mimic the knowledge of experienced operators. Twelve scenarios of three colored object combinations have been successfully tested and evaluated by using the developed controlled image-based robot tracker. Classical PID control failed to handle some tracking scenarios in this study. The proposed adaptive fuzzy PID control achieved the best accurate results with the minimum average final error of 13.8 cm to reach the colored targets, while our designed custom PID control is efficient in saving both average time and traveling distance of 6.6 s and 14.3 cm, respectively. These promising results demonstrate the feasibility of applying our developed image-based robotic system in a colored object-tracking environment to reduce human workloads. [ABSTRACT FROM AUTHOR]
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- 2024
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10. Intuitionistic Fuzzy Biofeedback Control of Implanted Dual-Sensor Cardiac Pacemakers.
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Alshahrani, Hussain, Alshahrani, Amnah, Karar, Mohamed Esmail, and Ramadan, Ebrahim A.
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CARDIAC pacemakers ,INTELLIGENT control systems ,MYOCARDIUM ,FUZZY logic ,HEART diseases - Abstract
Cardiac pacemakers are used for handling bradycardia, which is a cardiac rhythm of usually less than 60 beats per minute. Therapeutic dual-sensor pacemakers aim to preserve or restore the normal electromechanical activity of the cardiac muscle. In this article, a novel intelligent controller has been developed for implanted dual-sensor cardiac pacemakers. The developed controller is mainly based on intuitionistic fuzzy logic (IFL). The main advantage of the developed IFL controller is its ability to merge the qualitative expert knowledge of cardiologists in the proposed design of controlled pacemakers. Additionally, the implication of non-membership functions with the uncertainty term plays a key role in the developed fuzzy controller for improving the performance of a cardiac pacemaker over other fuzzy control schemes in previous studies. Moreover, the proposed pacemaker control system is efficient for managing all health-status conditions and constraints during the different daily activities of cardiac patients. Consequently, the healthcare of patients with implanted dual-sensor pacemakers can be efficiently improved intuitively. [ABSTRACT FROM AUTHOR]
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- 2024
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11. Optimal adaptive intuitionistic fuzzy logic control of anti-cancer drug delivery systems
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Karar, Mohamed Esmail, El-Garawany, Ahmed Hamdy, and El-Brawany, Mohamed
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- 2020
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12. Cascaded deep learning classifiers for computer-aided diagnosis of COVID-19 and pneumonia diseases in X-ray scans
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Karar, Mohamed Esmail, Hemdan, Ezz El-Din, and Shouman, Marwa A.
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- 2021
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13. Efficient Intelligent E-Learning Behavior-Based Analytics of Student's Performance Using Deep Forest Model.
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Alotaibi, Raed, Reyad, Omar, and Karar, Mohamed Esmail
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E-learning behavior data indicates several students' activities on the e-learning platform such as the number of accesses to a set of resources and number of participants in lectures. This article proposes a new analytics system to support academic evaluation for students via e-learning activities to overcome the challenges faced by traditional learning environments. The proposed e-learning analytics system includes a new deep forest model. It consists of multistage cascade random forests with minimal hyperparameters compared to traditional deep neural networks. The developed forest model can analyze each student's activities during the use of an e-learning platform to give accurate expectations of the student's performance before ending the semester and/or the final exam. Experiments have been conducted on the Open University Learning Analytics Dataset (OULAD) of 32,593 students. Our proposed deep model showed a competitive accuracy score of 98.0% compared to artificial intelligence-based models, such as Convolutional Neural Network (CNN) and Long Short-Term Memory (LSTM) in previous studies. That allows academic advisors to support expected failed students significantly and improve their academic level at the right time. Consequently, the proposed analytics system can enhance the quality of educational services for students in an innovative e-learning framework. [ABSTRACT FROM AUTHOR]
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- 2024
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14. A simple and accurate method for computer-aided transapical aortic valve replacement
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Karar, Mohamed Esmail, Merk, Denis R., Falk, Volkmar, and Burgert, Oliver
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- 2016
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15. Intelligent Networked Control of Vasoactive Drug Infusion for Patients with Uncertain Sensitivity.
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Karar, Mohamed Esmail and Mahmoud, Amged Sayed A.
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DRUG infusion pumps ,HYPERTENSION ,TELEMEDICINE ,FUZZY control systems ,MACHINE learning - Abstract
Abnormal high blood pressure or hypertension is still the leading risk factor for death and disability worldwide. This paper presents a new intelligent networked control of medical drug infusion system to regulate the mean arterial blood pressure for hypertensive patients with different health status conditions. The infusion of vasoactive drugs to patients endures various issues, such as variation of sensitivity and noise, which require effective and powerful systems to ensure robustness and good performance. The developed intelligent networked system is composed of a hybrid control scheme of interval type-2 fuzzy (IT2F) logic and teaching-learning-based optimization (TLBO) algorithm. This networked IT2F control is capable of managing the uncertain sensitivity of the patient to anti-hypertensive drugs successfully. To avoid the manual selection of control parameter values, the TLBO algorithm is mainly used to automatically find the best parameter values of the networked IT2F controller. The simulation results showed that the optimized networked IT2F achieved a good performance under external disturbances. A comparative study has also been conducted to emphasize the outperformance of the developed controller against traditional PID and type-1 fuzzy controllers.Moreover, the comparative evaluation demonstrated that the performance of the developed networked IT2F controller is superior to other control strategies in previous studies to handle unknown patients' sensitivity to infused vasoactive drugs in a noisy environment. [ABSTRACT FROM AUTHOR]
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- 2023
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16. Developed Fall Detection of Elderly Patients in Internet of Healthcare Things.
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Reyad, Omar, Shehata, Hazem Ibrahim, and Karar, Mohamed Esmail
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ARTIFICIAL neural networks ,OLDER patients ,MACHINE learning ,RANDOM forest algorithms ,OLDER people - Abstract
Falling is among the most harmful events older adults may encounter. With the continuous growth of the aging population in many societies, developing effective fall detection mechanisms empowered by machine learning technologies and easily integrable with existing healthcare systems becomes essential. This paper presents a new healthcare Internet of Health Things (IoHT) architecture built around an ensemble machine learning-based fall detection system (FDS) for older people. Compared to deep neural networks, the ensemble multi-stage random forest model allows the extraction of an optimal subset of fall detection features with minimal hyperparameters. The number of cascaded random forest stages is automatically optimized. This study uses a public dataset of fall detection samples called SmartFall to validate the developed fall detection system. The SmartFall dataset is collected based on the acquired measurements of the three-axis accelerometer in a smartwatch. Each scenario in this dataset is classified and labeled as a fall or a non-fall. In comparison to the three machine learning models—K-nearest neighbors (KNN), decision tree (DT), and standard random forest (SRF), the proposed ensemble classifier outperformed the other models and achieved 98.4% accuracy. The developed healthcare IoHT framework can be realized for detecting fall accidents of older people by taking security and privacy concerns into account in future work. [ABSTRACT FROM AUTHOR]
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- 2023
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17. Model-Updated Image-Guided Minimally Invasive Off-Pump Transcatheter Aortic Valve Implantation
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Karar, Mohamed Esmail, John, Matthias, Holzhey, David, Falk, Volkmar, Mohr, Friedrich-Wilhelm, Burgert, Oliver, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Fichtinger, Gabor, editor, Martel, Anne, editor, and Peters, Terry, editor
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- 2011
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18. Deep Forest-Based Fall Detection in Internet of Medical Things Environment.
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Karar, Mohamed Esmail, Reyad, Omar, and Shehata, Hazem Ibrahim
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INTERNET of things ,DEEP learning ,ACCELEROMETERS ,CONVOLUTIONAL neural networks ,WIRELESS sensor networks ,MEDICAL databases - Abstract
This article introduces a new medical internet of things (IoT) framework for intelligent fall detection system of senior people based on our proposed deep forest model. The cascade multi-layer structure of deep forest classifier allows to generate new features at each level with minimal hyperparameters compared to deep neural networks. Moreover, the optimal number of the deep forest layers is automatically estimated based on the early stopping criteria of validation accuracy value at each generated layer. The suggested forest classifier was successfully tested and evaluated using a public SmartFall dataset, which is acquired from three-axis accelerometer in a smartwatch. It includes 92781 training samples and 91025 testing samples with two labeled classes, namely non-fall and fall. Classification results of our deep forest classifier demonstrated a superior performance with the best accuracy score of 98.0% compared to three machine learning models, i.e., K-nearest neighbors, decision trees and traditional random forest, and two deep learning models, which are dense neural networks and convolutional neural networks. By considering security and privacy aspects in the future work, our proposed medical IoT framework for fall detection of old people is valid for real-time healthcare application deployment. [ABSTRACT FROM AUTHOR]
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- 2023
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19. A Survey of IoT-Based Fall Detection for Aiding Elderly Care: Sensors, Methods, Challenges and Future Trends
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Karar, Mohamed Esmail, primary, Shehata, Hazem Ibrahim, additional, and Reyad, Omar, additional
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- 2022
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20. Intelligent Medical IoT-Enabled Automated Microscopic Image Diagnosis of Acute Blood Cancers
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Karar, Mohamed Esmail, primary, Alotaibi, Bandar, additional, and Alotaibi, Munif, additional
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- 2022
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21. CovidXplus-A New Mobile Application for Image-Guided Diagnosis of COVID-19 Patients
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Karar, Mohamed Esmail, primary and Ahmad, Bilal, additional
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- 2022
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22. Automated Diagnosis of Heart Sounds Using Rule-Based Classification Tree
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Karar, Mohamed Esmail, El-Khafif, Sahar H., and El-Brawany, Mohamed A.
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- 2017
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23. Multi-Label Transfer Learning for Identifying Lung Diseases using Chest X-Rays
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El-Fiky, Azza, primary, Shouman, Marwa Ahmed, additional, Hamada, Salwa, additional, El-Sayed, Ayman, additional, and Karar, Mohamed Esmail, additional
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- 2021
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24. Image-Guided Transapical Aortic Valve Implantation: Sensorless Tracking of Stenotic Valve Landmarks in Live Fluoroscopic Images
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Merk, Denis R., Karar, Mohamed Esmail, Chalopin, Claire, Holzhey, David, Falk, Volkmar, Mohr, Friedrich W., and Burgert, Oliver
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- 2011
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25. Hash-enhanced elliptic curve bit-string generator for medical image encryption
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Reyad, Omar, primary, Hamed, Kadry, additional, and Karar, Mohamed Esmail, additional
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- 2020
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26. Cascaded deep learning classifiers for computer-aided diagnosis of COVID-19 and pneumonia diseases in X-ray scans
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Karar, Mohamed Esmail, primary, Hemdan, Ezz El-Din, additional, and Shouman, Marwa A., additional
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- 2020
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27. Adversarial Neural Network Classifiers for COVID-19 Diagnosis in Ultrasound Images.
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Karar, Mohamed Esmail, Shouman, Marwa Ahmed, and Chalopin, Claire
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COVID-19 ,COVID-19 testing ,COMPUTER-aided diagnosis ,DEEP learning ,COVID-19 pandemic ,GENERATIVE adversarial networks - Abstract
The novel Coronavirus disease 2019 (COVID-19) pandemic has begun in China and is still affecting thousands of patient livesworldwide daily. AlthoughChest X-ray and Computed Tomography are the gold standardmedical imaging modalities for diagnosing potentially infected COVID-19 cases, applying Ultrasound (US) imaging technique to accomplish this crucial diagnosing task has attracted many physicians recently. In this article, we propose two modified deep learning classifiers to identify COVID-19 and pneumonia diseases in US images, based on generative adversarial neural networks (GANs). The proposed image classifiers are a semi-supervised GAN and a modifiedGANwith auxiliary classifier. Each one includes a modified discriminator to identify the class of the US image using semi-supervised learning technique, keeping its main function of defining the “realness” of tested images. Extensive tests have been successfully conducted on public dataset of US images acquired with a convex US probe. This study demonstrated the feasibility of using chest US images with two GAN classifiers as a new radiological tool for clinical check of COVID-19 patients. The results of our proposed GAN models showed that high accuracy values above 91.0% were obtained under different sizes of limited training data, outperforming other deep learning-based methods, such as transfer learning models in the recent studies. Consequently, the clinical implementation of our computer-aided diagnosis of US-COVID-19 is the future work of this study. [ABSTRACT FROM AUTHOR]
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- 2022
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28. Intelligent IoT-Aided Early Sound Detection of Red Palm Weevils.
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Karar, Mohamed Esmail, Reyad, Omar, Abdel-Aty, Abdel-Haleem, Owyed, Saud, and Hassan, Mohd F.
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PALMS ,PRECISION farming ,DEEP learning ,DATE palm ,CURCULIONIDAE ,WIRELESS sensor networks ,ARTIFICIAL intelligence - Abstract
Smart precision agriculture utilizes modern information and wireless communication technologies to achieve challenging agricultural processes. Therefore, Internet of Things (IoT) technology can be applied to monitor and detect harmful insect pests such as red palm weevils (RPWs) in the farms of date palm trees. In this paper, we propose a new IoT-based framework for early sound detection of RPWs using fine-tuned transfer learning classifier, namely InceptionResNet-V2. The sound sensors, namely TreeVibes devices are carefullymounted on each palm trunk to setup wireless sensor networks in the farm. Palm trees are labeled based on the sensor node number to identify the infested cases. Then, the acquired audio signals are sent to a cloud server for further on-line analysis by our fine-tuned deep transfer learning model, i.e., InceptionResNet-V2. The proposed infestation classifier has been successfully validated on the public TreeVibes database. It includes total short recordings of 1754 samples, such that the clean and infested signals are 1754 and 731 samples, respectively. Compared to other deep learning models in the literature, our proposed InceptionResNet-V2 classifier achieved the best performance on the public database of TreeVibes audio recordings. The resulted classification accuracy score was 97.18%. Using 10-fold cross validation, the fine-tuned InceptionResNet-V2 achieved the best average accuracy score and standard deviation of 94.53% and±1.69, respectively. Applying the proposed intelligent IoT-aided detection system of RPWs in date palm farms is the main prospect of this research work. [ABSTRACT FROM AUTHOR]
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- 2021
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29. Lightweight Transfer Learning Models for Ultrasound-Guided Classification of COVID-19 Patients.
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Karar, Mohamed Esmail, Reyad, Omar, Abd-Elnaby, Mohammed, Abdel-Aty, Abdel-Haleem, and Shouman, Marwa Ahmed
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COVID-19 ,DEEP learning ,COVID-19 pandemic ,CONVOLUTIONAL neural networks ,ARTIFICIAL intelligence - Abstract
Lightweight deep convolutional neural networks (CNNs) present a good solution to achieve fast and accurate image-guided diagnostic procedures of COVID-19 patients. Recently, advantages of portable Ultrasound (US) imaging such as simplicity and safe procedures have attracted many radiologists for scanning suspected COVID-19 cases. In this paper, a new framework of lightweight deep learning classifiers, namely COVID-LWNet is proposed to identify COVID-19 and pneumonia abnormalities in US images. Compared to traditional deep learning models, lightweight CNNs showed significant performance of real-time vision applications by usingmobile devices with limited hardware resources. Four main lightweight deep learning models, namely MobileNets, ShuffleNets, MENet and MnasNet have been proposed to identify the health status of lungs using US images. Public image dataset (POCUS) was used to validate our proposed COVID-LWNet framework successfully. Three classes of infectious COVID-19, bacterial pneumonia, and the healthy lungwere investigated in this study. The results showed that the performance of our proposedMnasNet classifier achieved the best accuracy score and shortest training time of 99.0% and 647.0 s, respectively. This paper demonstrates the feasibility of using our proposed COVID-LWNet framework as a new mobilebased radiological tool for clinical diagnosis of COVID-19 and other lung diseases. [ABSTRACT FROM AUTHOR]
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- 2021
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30. Adaptive Heart Rate Regulation Using Implantable Pacemaker with Artificial Neural Network-Based Backstepping Controller
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Karar, Mohamed Esmail, primary
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- 2018
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31. Robust RBF neural network-based backstepping controller for implantable cardiac pacemakers
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Karar, Mohamed Esmail, primary
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- 2018
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32. Practical microcontroller-based simulator of graphical heart sounds with disorders
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Karar, Mohamed Esmail, primary
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- 2017
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33. A Simulation Study of Adaptive Force Controller for Medical Robotic Liver Ultrasound Guidance
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Karar, Mohamed Esmail, primary
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- 2017
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34. Embedded heart sounds and murmurs generator based on discrete wavelet transform
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Karar, Mohamed Esmail, primary and El-Brawany, Mohamed, additional
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- 2016
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35. A Simulation Study of Adaptive Force Controller for Medical Robotic Liver Ultrasound Guidance.
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Karar, Mohamed Esmail
- Subjects
- *
MEDICAL robotics , *PID controllers , *ULTRASONIC imaging - Abstract
Compensation for the respiratory motion is a major challenge in the control design of medical robot ultrasound for accurately scanning the liver. Therefore, this paper presents an adaptive fuzzy proportional-integral-derivative (PID) force control of robot-assisted ultrasound to improve the guidance performance for anatomical or pathological structures of the liver under free breathing. A six degree-of-freedom robotic arm equipped with a 2-D ultrasound probe and a force sensor is simulated to perform the guidance procedure of the liver. The respiratory motion is also modeled and synchronized with retrospective liver ultrasound images. Without a priori knowledge of the nonlinear dynamic characteristics or mathematical modeling of the robot, the developed force controller exploits the advantages of fuzzy logic to directly auto-tune the PID controller gains for manipulating the robotic ultrasound probe on the patient’s abdomen at desired force levels in real time. A simulation framework has been developed to test the robotic force controller using four ultrasound image sequences of the liver. Compared to conventional PID controller with fixed gains, the adaptive fuzzy PID controller showed significantly better performance by resulting minimum tracked force errors of approximately 0.3 and 0.01 N with and without force sensor noise, respectively, for all tested image datasets. This simulation study presents potentially a good solution to accomplish the tracking task of desired probe forces during the robotic liver ultrasound guidance based on the developed fuzzy PID controller. [ABSTRACT FROM AUTHOR]
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- 2018
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36. Development of a Surgical Assistance System for Guiding Transcatheter Aortic Valve Implantation
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KARAR, Mohamed Esmail Abdel Razek Hassan, Burgert, Oliver, Deserno, Thomas, Scheuermann, Gerik, and Universität Leipzig
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ddc:000 ,Computer assistierte Chirurgie, Medizinische Bildverarbeitung, Transkatheter Aortenklappenimplantation ,Computer Assisted Surgery, Medical image processing, Transcatheter Aortic Valve Implantation - Abstract
Development of image-guided interventional systems is growing up rapidly in the recent years. These new systems become an essential part of the modern minimally invasive surgical procedures, especially for the cardiac surgery. Transcatheter aortic valve implantation (TAVI) is a recently developed surgical technique to treat severe aortic valve stenosis in elderly and high-risk patients. The placement of stented aortic valve prosthesis is crucial and typically performed under live 2D fluoroscopy guidance. To assist the placement of the prosthesis during the surgical procedure, a new fluoroscopy-based TAVI assistance system has been developed. The developed assistance system integrates a 3D geometrical aortic mesh model and anatomical valve landmarks with live 2D fluoroscopic images. The 3D aortic mesh model and landmarks are reconstructed from interventional angiographic and fluoroscopic C-arm CT system, and a target area of valve implantation is automatically estimated using these aortic mesh models. Based on template-based tracking approach, the overlay of visualized 3D aortic mesh model, landmarks and target area of implantation onto fluoroscopic images is updated by approximating the aortic root motion from a pigtail catheter motion without contrast agent. A rigid intensity-based registration method is also used to track continuously the aortic root motion in the presence of contrast agent. Moreover, the aortic valve prosthesis is tracked in fluoroscopic images to guide the surgeon to perform the appropriate placement of prosthesis into the estimated target area of implantation. An interactive graphical user interface for the surgeon is developed to initialize the system algorithms, control the visualization view of the guidance results, and correct manually overlay errors if needed. Retrospective experiments were carried out on several patient datasets from the clinical routine of the TAVI in a hybrid operating room. The maximum displacement errors were small for both the dynamic overlay of aortic mesh models and tracking the prosthesis, and within the clinically accepted ranges. High success rates of the developed assistance system were obtained for all tested patient datasets. The results show that the developed surgical assistance system provides a helpful tool for the surgeon by automatically defining the desired placement position of the prosthesis during the surgical procedure of the TAVI. Die Entwicklung bildgeführter interventioneller Systeme wächst rasant in den letzten Jahren. Diese neuen Systeme werden zunehmend ein wesentlicher Bestandteil der technischen Ausstattung bei modernen minimal-invasiven chirurgischen Eingriffen. Diese Entwicklung gilt besonders für die Herzchirurgie. Transkatheter Aortenklappen-Implantation (TAKI) ist eine neue entwickelte Operationstechnik zur Behandlung der schweren Aortenklappen-Stenose bei alten und Hochrisiko-Patienten. Die Platzierung der Aortenklappenprothese ist entscheidend und wird in der Regel unter live-2D-fluoroskopischen Bildgebung durchgeführt. Zur Unterstützung der Platzierung der Prothese während des chirurgischen Eingriffs wurde in dieser Arbeit ein neues Fluoroskopie-basiertes TAKI Assistenzsystem entwickelt. Das entwickelte Assistenzsystem überlagert eine 3D-Geometrie des Aorten-Netzmodells und anatomischen Landmarken auf live-2D-fluoroskopische Bilder. Das 3D-Aorten-Netzmodell und die Landmarken werden auf Basis der interventionellen Angiographie und Fluoroskopie mittels eines C-Arm-CT-Systems rekonstruiert. Unter Verwendung dieser Aorten-Netzmodelle wird das Zielgebiet der Klappen-Implantation automatisch geschätzt. Mit Hilfe eines auf Template Matching basierenden Tracking-Ansatzes wird die Überlagerung des visualisierten 3D-Aorten-Netzmodells, der berechneten Landmarken und der Zielbereich der Implantation auf fluoroskopischen Bildern korrekt überlagert. Eine kompensation der Aortenwurzelbewegung erfolgt durch Bewegungsverfolgung eines Pigtail-Katheters in Bildsequenzen ohne Kontrastmittel. Eine starrere Intensitätsbasierte Registrierungsmethode wurde verwendet, um kontinuierlich die Aortenwurzelbewegung in Bildsequenzen mit Kontrastmittelgabe zu detektieren. Die Aortenklappenprothese wird in die fluoroskopischen Bilder eingeblendet und dient dem Chirurg als Leitfaden für die richtige Platzierung der realen Prothese. Eine interaktive Benutzerschnittstelle für den Chirurg wurde zur Initialisierung der Systemsalgorithmen, zur Steuerung der Visualisierung und für manuelle Korrektur eventueller Überlagerungsfehler entwickelt. Retrospektive Experimente wurden an mehreren Patienten-Datensätze aus der klinischen Routine der TAKI in einem Hybrid-OP durchgeführt. Hohe Erfolgsraten des entwickelten Assistenzsystems wurden für alle getesteten Patienten-Datensätze erzielt. Die Ergebnisse zeigen, dass das entwickelte chirurgische Assistenzsystem ein hilfreiches Werkzeug für den Chirurg bei der Platzierung Position der Prothese während des chirurgischen Eingriffs der TAKI bietet.
- Published
- 2011
37. Image-Guided Transcatheter Aortic Valve Implantation Assistance System
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Karar, Mohamed Esmail
- Subjects
Medical / Cardiology - Abstract
Image-Guided Transcatheter Aortic Valve Implantation Assistance System
- Published
- 2011
38. Development of a Surgical Assistance System for Guiding Transcatheter Aortic Valve Implantation
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Burgert, Oliver, Deserno, Thomas, Scheuermann, Gerik, Universität Leipzig, KARAR, Mohamed Esmail Abdel Razek Hassan, Burgert, Oliver, Deserno, Thomas, Scheuermann, Gerik, Universität Leipzig, and KARAR, Mohamed Esmail Abdel Razek Hassan
- Abstract
Development of image-guided interventional systems is growing up rapidly in the recent years. These new systems become an essential part of the modern minimally invasive surgical procedures, especially for the cardiac surgery. Transcatheter aortic valve implantation (TAVI) is a recently developed surgical technique to treat severe aortic valve stenosis in elderly and high-risk patients. The placement of stented aortic valve prosthesis is crucial and typically performed under live 2D fluoroscopy guidance. To assist the placement of the prosthesis during the surgical procedure, a new fluoroscopy-based TAVI assistance system has been developed. The developed assistance system integrates a 3D geometrical aortic mesh model and anatomical valve landmarks with live 2D fluoroscopic images. The 3D aortic mesh model and landmarks are reconstructed from interventional angiographic and fluoroscopic C-arm CT system, and a target area of valve implantation is automatically estimated using these aortic mesh models. Based on template-based tracking approach, the overlay of visualized 3D aortic mesh model, landmarks and target area of implantation onto fluoroscopic images is updated by approximating the aortic root motion from a pigtail catheter motion without contrast agent. A rigid intensity-based registration method is also used to track continuously the aortic root motion in the presence of contrast agent. Moreover, the aortic valve prosthesis is tracked in fluoroscopic images to guide the surgeon to perform the appropriate placement of prosthesis into the estimated target area of implantation. An interactive graphical user interface for the surgeon is developed to initialize the system algorithms, control the visualization view of the guidance results, and correct manually overlay errors if needed. Retrospective experiments were carried out on several patient datasets from the clinical routine of the TAVI in a hybrid operating room. The maximum displacement errors were small fo, Die Entwicklung bildgeführter interventioneller Systeme wächst rasant in den letzten Jahren. Diese neuen Systeme werden zunehmend ein wesentlicher Bestandteil der technischen Ausstattung bei modernen minimal-invasiven chirurgischen Eingriffen. Diese Entwicklung gilt besonders für die Herzchirurgie. Transkatheter Aortenklappen-Implantation (TAKI) ist eine neue entwickelte Operationstechnik zur Behandlung der schweren Aortenklappen-Stenose bei alten und Hochrisiko-Patienten. Die Platzierung der Aortenklappenprothese ist entscheidend und wird in der Regel unter live-2D-fluoroskopischen Bildgebung durchgeführt. Zur Unterstützung der Platzierung der Prothese während des chirurgischen Eingriffs wurde in dieser Arbeit ein neues Fluoroskopie-basiertes TAKI Assistenzsystem entwickelt. Das entwickelte Assistenzsystem überlagert eine 3D-Geometrie des Aorten-Netzmodells und anatomischen Landmarken auf live-2D-fluoroskopische Bilder. Das 3D-Aorten-Netzmodell und die Landmarken werden auf Basis der interventionellen Angiographie und Fluoroskopie mittels eines C-Arm-CT-Systems rekonstruiert. Unter Verwendung dieser Aorten-Netzmodelle wird das Zielgebiet der Klappen-Implantation automatisch geschätzt. Mit Hilfe eines auf Template Matching basierenden Tracking-Ansatzes wird die Überlagerung des visualisierten 3D-Aorten-Netzmodells, der berechneten Landmarken und der Zielbereich der Implantation auf fluoroskopischen Bildern korrekt überlagert. Eine kompensation der Aortenwurzelbewegung erfolgt durch Bewegungsverfolgung eines Pigtail-Katheters in Bildsequenzen ohne Kontrastmittel. Eine starrere Intensitätsbasierte Registrierungsmethode wurde verwendet, um kontinuierlich die Aortenwurzelbewegung in Bildsequenzen mit Kontrastmittelgabe zu detektieren. Die Aortenklappenprothese wird in die fluoroskopischen Bilder eingeblendet und dient dem Chirurg als Leitfaden für die richtige Platzierung der realen Prothese. Eine interaktive Benutzerschnittstelle für den Chirurg wurde zur Initialisieru
- Published
- 2012
39. Development of a Surgical Assistance System for Guiding Transcatheter Aortic Valve Implantation
- Author
-
Deserno, Thomas, Scheuermann, Gerik, Universität Leipzig, KARAR, Mohamed Esmail Abdel Razek Hassan, Deserno, Thomas, Scheuermann, Gerik, Universität Leipzig, and KARAR, Mohamed Esmail Abdel Razek Hassan
- Abstract
Development of image-guided interventional systems is growing up rapidly in the recent years. These new systems become an essential part of the modern minimally invasive surgical procedures, especially for the cardiac surgery. Transcatheter aortic valve implantation (TAVI) is a recently developed surgical technique to treat severe aortic valve stenosis in elderly and high-risk patients. The placement of stented aortic valve prosthesis is crucial and typically performed under live 2D fluoroscopy guidance. To assist the placement of the prosthesis during the surgical procedure, a new fluoroscopy-based TAVI assistance system has been developed. The developed assistance system integrates a 3D geometrical aortic mesh model and anatomical valve landmarks with live 2D fluoroscopic images. The 3D aortic mesh model and landmarks are reconstructed from interventional angiographic and fluoroscopic C-arm CT system, and a target area of valve implantation is automatically estimated using these aortic mesh models. Based on template-based tracking approach, the overlay of visualized 3D aortic mesh model, landmarks and target area of implantation onto fluoroscopic images is updated by approximating the aortic root motion from a pigtail catheter motion without contrast agent. A rigid intensity-based registration method is also used to track continuously the aortic root motion in the presence of contrast agent. Moreover, the aortic valve prosthesis is tracked in fluoroscopic images to guide the surgeon to perform the appropriate placement of prosthesis into the estimated target area of implantation. An interactive graphical user interface for the surgeon is developed to initialize the system algorithms, control the visualization view of the guidance results, and correct manually overlay errors if needed. Retrospective experiments were carried out on several patient datasets from the clinical routine of the TAVI in a hybrid operating room. The maximum displacement errors were small fo, Die Entwicklung bildgeführter interventioneller Systeme wächst rasant in den letzten Jahren. Diese neuen Systeme werden zunehmend ein wesentlicher Bestandteil der technischen Ausstattung bei modernen minimal-invasiven chirurgischen Eingriffen. Diese Entwicklung gilt besonders für die Herzchirurgie. Transkatheter Aortenklappen-Implantation (TAKI) ist eine neue entwickelte Operationstechnik zur Behandlung der schweren Aortenklappen-Stenose bei alten und Hochrisiko-Patienten. Die Platzierung der Aortenklappenprothese ist entscheidend und wird in der Regel unter live-2D-fluoroskopischen Bildgebung durchgeführt. Zur Unterstützung der Platzierung der Prothese während des chirurgischen Eingriffs wurde in dieser Arbeit ein neues Fluoroskopie-basiertes TAKI Assistenzsystem entwickelt. Das entwickelte Assistenzsystem überlagert eine 3D-Geometrie des Aorten-Netzmodells und anatomischen Landmarken auf live-2D-fluoroskopische Bilder. Das 3D-Aorten-Netzmodell und die Landmarken werden auf Basis der interventionellen Angiographie und Fluoroskopie mittels eines C-Arm-CT-Systems rekonstruiert. Unter Verwendung dieser Aorten-Netzmodelle wird das Zielgebiet der Klappen-Implantation automatisch geschätzt. Mit Hilfe eines auf Template Matching basierenden Tracking-Ansatzes wird die Überlagerung des visualisierten 3D-Aorten-Netzmodells, der berechneten Landmarken und der Zielbereich der Implantation auf fluoroskopischen Bildern korrekt überlagert. Eine kompensation der Aortenwurzelbewegung erfolgt durch Bewegungsverfolgung eines Pigtail-Katheters in Bildsequenzen ohne Kontrastmittel. Eine starrere Intensitätsbasierte Registrierungsmethode wurde verwendet, um kontinuierlich die Aortenwurzelbewegung in Bildsequenzen mit Kontrastmittelgabe zu detektieren. Die Aortenklappenprothese wird in die fluoroskopischen Bilder eingeblendet und dient dem Chirurg als Leitfaden für die richtige Platzierung der realen Prothese. Eine interaktive Benutzerschnittstelle für den Chirurg wurde zur Initialisieru
- Published
- 2012
40. A simple and accurate method for computer-aided transapical aortic valve replacement
- Author
-
Volkmar Falk, Denis R. Merk, Oliver Burgert, Mohamed Esmail Karar, University of Zurich, and Karar, Mohamed Esmail
- Subjects
Aortic valve ,medicine.medical_specialty ,1707 Computer Vision and Pattern Recognition ,Computer science ,medicine.medical_treatment ,Health Informatics ,610 Medicine & health ,030204 cardiovascular system & hematology ,Prosthesis ,1704 Computer Graphics and Computer-Aided Design ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Imaging, Three-Dimensional ,Aortic valve replacement ,medicine ,Minimally invasive cardiac surgery ,Fluoroscopy ,Humans ,2741 Radiology, Nuclear Medicine and Imaging ,Radiology, Nuclear Medicine and imaging ,book ,3614 Radiological and Ultrasound Technology ,2718 Health Informatics ,Heart Valve Prosthesis Implantation ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,Aortic Valve Stenosis ,medicine.disease ,Computer Graphics and Computer-Aided Design ,Computer aided surgery ,10020 Clinic for Cardiac Surgery ,Stenosis ,medicine.anatomical_structure ,Aortic valve stenosis ,Aortic Valve ,Heart Valve Prosthesis ,book.journal ,Computer Vision and Pattern Recognition ,Radiology - Abstract
Background and purpose Transapical aortic valve replacement (TAVR) is a recent minimally invasive surgical treatment technique for elderly and high-risk patients with severe aortic stenosis. In this paper, a simple and accurate image-based method is introduced to aid the intra-operative guidance of TAVR procedure under 2-D X-ray fluoroscopy. Methods The proposed method fuses a 3-D aortic mesh model and anatomical valve landmarks with live 2-D fluoroscopic images. The 3-D aortic mesh model and landmarks are reconstructed from interventional X-ray C-arm CT system, and a target area for valve implantation is automatically estimated using these aortic mesh models. Based on template-based tracking approach, the overlay of visualized 3-D aortic mesh model, landmarks and target area of implantation is updated onto fluoroscopic images by approximating the aortic root motion from a pigtail catheter motion without contrast agent. Also, a rigid intensity-based registration algorithm is used to track continuously the aortic root motion in the presence of contrast agent. Furthermore, a sensorless tracking of the aortic valve prosthesis is provided to guide the physician to perform the appropriate placement of prosthesis into the estimated target area of implantation. Results Retrospective experiments were carried out on fifteen patient datasets from the clinical routine of the TAVR. The maximum displacement errors were less than 2.0 mm for both the dynamic overlay of aortic mesh models and image-based tracking of the prosthesis, and within the clinically accepted ranges. Moreover, high success rates of the proposed method were obtained above 91.0% for all tested patient datasets. Conclusion The results showed that the proposed method for computer-aided TAVR is potentially a helpful tool for physicians by automatically defining the accurate placement position of the prosthesis during the surgical procedure.
- Published
- 2016
41. Image-guided transapical aortic valve implantation: sensorless tracking of stenotic valve landmarks in live fluoroscopic images.
- Author
-
Merk DR, Karar ME, Chalopin C, Holzhey D, Falk V, Mohr FW, and Burgert O
- Abstract
Objective: Aortic valve stenosis is one of the most frequently acquired valvular heart diseases, accounting for almost 70% of valvular cardiac surgery. Transapical transcatheter aortic valve implantation has recently become a suitable minimally invasive technique for high-risk and elderly patients with severe aortic stenosis. In this article, we aim to automatically define a target area of valve implantation, namely, the area between the coronary ostia and the lowest points of two aortic valve cusps. Therefore, we present a new image-based tracking method of these aortic landmarks to assist in the placement of aortic valve prosthesis under live 2D fluoroscopy guidance., Methods: We propose a rigid intensity-based image registration technique for tracking valve landmarks in 2D fluoroscopic image sequences, based on a real-time alignment of a contrast image including the initialized manual valve landmarks to each image of sequence. The contrast image is automatically detected to visualize aortic valve features when the aortic root is filled with a contrast agent., Results: Our registration-based tracking method has been retrospectively applied to 10 fluoroscopic image sequences from routine transapical aortic valve implantation procedures. Most of all tested fluoroscopic images showed a successful tracking of valve landmarks, especially for the images without contrast agent injections., Conclusions: A new intraoperative image-based method has been developed for tracking aortic valve landmarks in live 2D fluoroscopic images to assist transapical aortic valve implantations and to increase the overall safety of surgery as well.
- Published
- 2011
- Full Text
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