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Your search keyword '"Karamikamkar, Solmaz"' showing total 29 results
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29 results on '"Karamikamkar, Solmaz"'

1. Modularity-based mathematical modeling of ligand inter-nanocluster connectivity for unraveling reversible stem cell regulation

Author

Kim, Chowon, Kang, Nayeon, Min, Sunhong, Thangam, Ramar, Lee, Sungkyu, Hong, Hyunsik, Kim, Kanghyeon, Kim, Seong Yeol, Kim, Dahee, Rha, Hyunji, Tag, Kyong-Ryol, Lee, Hyun-Jeong, Singh, Nem, Jeong, Daun, Hwang, Jangsun, Kim, Yuri, Park, Sangwoo, Lee, Hyesung, Kim, Taeeon, Son, Sang Wook, Park, Steve, Karamikamkar, Solmaz, Zhu, Yangzhi, Hassani Najafabadi, Alireza, Chu, Zhiqin, Sun, Wujin, Zhao, Pengchao, Zhang, Kunyu, Bian, Liming, Song, Hyun-Cheol, Park, Sung-Gyu, Kim, Jong Seung, Lee, Sang-Yup, Ahn, Jae-Pyoung, Kim, Hong-Kyu, Zhang, Yu Shrike, and Kang, Heemin

Published
2024
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2. Photonic control of ligand nanospacing in self-assembly regulates stem cell fate

Author

Lee, Sungkyu, Yoo, Jounghyun, Bae, Gunhyu, Thangam, Ramar, Heo, Jeongyun, Park, Jung Yeon, Choi, Honghwan, Kim, Chowon, An, Jusung, Kim, Jungryun, Mun, Kwang Rok, Shin, Seungyong, Zhang, Kunyu, Zhao, Pengchao, Kim, Yuri, Kang, Nayeon, Han, Seong-Beom, Kim, Dahee, Yoon, Jiwon, Kang, Misun, Kim, Jihwan, Yang, Letao, Karamikamkar, Solmaz, Kim, Jinjoo, Zhu, Yangzhi, Najafabadi, Alireza Hassani, Song, Guosheng, Kim, Dong-Hwee, Lee, Ki-Bum, Oh, Soong Ju, Jung, Hyun-Do, Song, Hyun-Cheol, Jang, Woo Young, Bian, Liming, Chu, Zhiqin, Yoon, Juyoung, Kim, Jong Seung, Zhang, Yu Shrike, Kim, Yongju, Jang, Ho Seong, Kim, Sehoon, and Kang, Heemin

Published
2024
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13. Emerging 2D Nanomaterials‐Integrated Hydrogels: Advancements in Designing Theragenerative Materials for Bone Regeneration and Disease Therapy.

Author

Zorrón, Melanie, Cabrera, Agustín López, Sharma, Riya, Radhakrishnan, Janani, Abbaszadeh, Samin, Shahbazi, Mohammad‐Ali, Tafreshi, Omid Aghababaei, Karamikamkar, Solmaz, and Maleki, Hajar

Subjects
BONE regeneration, BONE diseases, TREATMENT effectiveness, HYDROGELS, CONTRAST media, LIGHT absorption
Abstract

This review highlights recent advancements in the synthesis, processing, properties, and applications of 2D‐material integrated hydrogels, with a focus on their performance in bone‐related applications. Various synthesis methods and types of 2D nanomaterials, including graphene, graphene oxide, transition metal dichalcogenides, black phosphorus, and MXene are discussed, along with strategies for their incorporation into hydrogel matrices. These composite hydrogels exhibit tunable mechanical properties, high surface area, strong near‐infrared (NIR) photon absorption and controlled release capabilities, making them suitable for a range of regeneration and therapeutic applications. In cancer therapy, 2D‐material‐based hydrogels show promise for photothermal and photodynamic therapies, and drug delivery (chemotherapy). The photothermal properties of these materials enable selective tumor ablation upon NIR irradiation, while their high drug‐loading capacity facilitates targeted and controlled release of chemotherapeutic agents. Additionally, 2D‐materials ‐infused hydrogels exhibit potent antibacterial activity, making them effective against multidrug‐resistant infections and disruption of biofilm generated on implant surface. Moreover, their synergistic therapy approach combines multiple treatment modalities such as photothermal, chemo, and immunotherapy to enhance therapeutic outcomes. In bio‐imaging, these materials serve as versatile contrast agents and imaging probes, enabling their real‐time monitoring during tumor imaging. Furthermore, in bone regeneration, most 2D‐materials incorporated hydrogels promote osteogenesis and tissue regeneration, offering potential solutions for bone defects repair. Overall, the integration of 2D materials into hydrogels presents a promising platform for developing multifunctional theragenerative biomaterials. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Aerogel‐Based Biomaterials for Biomedical Applications: From Fabrication Methods to Disease‐Targeting Applications (Adv. Sci. 23/2023)

Author

Karamikamkar, Solmaz, primary, Yalcintas, Ezgi Pinar, additional, Haghniaz, Reihaneh, additional, de Barros, Natan Roberto, additional, Mecwan, Marvin, additional, Nasiri, Rohollah, additional, Davoodi, Elham, additional, Nasrollahi, Fatemeh, additional, Erdem, Ahmet, additional, Kang, Heemin, additional, Lee, Junmin, additional, Zhu, Yangzhi, additional, Ahadian, Samad, additional, Jucaud, Vadim, additional, Maleki, Hajar, additional, Dokmeci, Mehmet Remzi, additional, Kim, Han‐Jun, additional, and Khademhosseini, Ali, additional

Published
2023
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17. Lab‐on‐a‐Contact Lens: Recent Advances and Future Opportunities in Diagnostics and Therapeutics

Author

Zhu, Yangzhi, Li, Shaopei, Li, Jinghang, Falcone, Natashya, Cui, Qingyu, Shah, Shilp, Hartel, Martin C., Yu, Ning, Young, Patric, de Barros, Natan Roberto, Wu, Zhuohong, Haghniaz, Reihaneh, Ermis, Menekse, Wang, Canran, Kang, Heemin, Lee, Junmin, Karamikamkar, Solmaz, Ahadian, Samad, Jucaud, Vadim, Dokmeci, Mehmet R., Kim, Han-Jun, Khademhosseini, Ali, Zhu, Yangzhi, Li, Shaopei, Li, Jinghang, Falcone, Natashya, Cui, Qingyu, Shah, Shilp, Hartel, Martin C., Yu, Ning, Young, Patric, de Barros, Natan Roberto, Wu, Zhuohong, Haghniaz, Reihaneh, Ermis, Menekse, Wang, Canran, Kang, Heemin, Lee, Junmin, Karamikamkar, Solmaz, Ahadian, Samad, Jucaud, Vadim, Dokmeci, Mehmet R., Kim, Han-Jun, and Khademhosseini, Ali

Abstract

The eye is one of the most complex organs in the human body, containing rich and critical physiological information (e.g., intraocular pressure, corneal temperature, and pH) as well as a library of metabolite biomarkers (e.g., glucose, proteins, and specific ions). Smart contact lenses (SCLs) can serve as a wearable intelligent ocular prosthetic device capable of non-invasive and continuous monitoring of various essential physical/biochemical parameters and drug loading/delivery for the treatment of ocular diseases. Advances in SCL technologies and the growing public interest in personalized health are accelerating SCL research more than ever before. Here, we discussed the current status and potential of SCL development through a comprehensive review from fabrication to applications to commercialization. First, we discuss the material, fabrication, and platform designs of the SCLs for the diagnostic and therapeutic applications. Then, we review the latest advances in diagnostic and therapeutic SCLs for clinical translation. Later, we summarize the established techniques for wearable power transfer and wireless data transmission applied to current SCL devices. We also provide an outlook, future opportunities, and challenges for developing next-generation SCL devices. With the rise in interest of SCL development, this comprehensive and essential review can serve as a new paradigm for the SCL devices.

Published
2022

18. Lab‐on‐a‐Contact Lens: Recent Advances and Future Opportunities in Diagnostics and Therapeutics

Author

Zhu, Yangzhi, primary, Li, Shaopei, additional, Li, Jinghang, additional, Falcone, Natashya, additional, Cui, Qingyu, additional, Shah, Shilp, additional, Hartel, Martin C., additional, Yu, Ning, additional, Young, Patric, additional, de Barros, Natan Roberto, additional, Wu, Zhuohong, additional, Haghniaz, Reihaneh, additional, Ermis, Menekse, additional, Wang, Canran, additional, Kang, Heemin, additional, Lee, Junmin, additional, Karamikamkar, Solmaz, additional, Ahadian, Samad, additional, Jucaud, Vadim, additional, Dokmeci, Mehmet R., additional, Kim, Han‐Jun, additional, and Khademhosseini, Ali, additional

Published
2022
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19. Advances in microfabrication technologies in tissue engineering and regenerative medicine

Author

Nadine, Sara, primary, Chung, Ada, additional, Diltemiz, Sibel Emir, additional, Yasuda, Brooke, additional, Lee, Charles, additional, Hosseini, Vahid, additional, Karamikamkar, Solmaz, additional, de Barros, Natan Roberto, additional, Mandal, Kalpana, additional, Advani, Shailesh, additional, Zamanian, Benjamin Behnam, additional, Mecwan, Marvin, additional, Zhu, Yangzhi, additional, Mofidfar, Mohammad, additional, Zare, Mohammad Reza, additional, Mano, João, additional, Dokmeci, Mehmet Remzi, additional, Alambeigi, Farshid, additional, and Ahadian, Samad, additional

Published
2022
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20. Laponite‐Based Nanomaterials for Drug Delivery

Author

Kiaee, Gita, primary, Dimitrakakis, Nikolaos, additional, Sharifzadeh, Shabnam, additional, Kim, Han‐Jun, additional, Avery, Reginald K., additional, Moghaddam, Kamyar Mollozadeh, additional, Haghniaz, Reihaneh, additional, Yalcintas, Ezgi Pinar, additional, Barros, Natan Roberto de, additional, Karamikamkar, Solmaz, additional, Libanori, Alberto, additional, Khademhosseini, Ali, additional, and Khoshakhlagh, Parastoo, additional

Published
2022
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22. Micro and Nanoscale Technologies for Diagnosis of Viral Infections

Author

Nasrollahi, Fatemeh, primary, Haghniaz, Reihaneh, additional, Hosseini, Vahid, additional, Davoodi, Elham, additional, Mahmoodi, Mahboobeh, additional, Karamikamkar, Solmaz, additional, Darabi, Mohammad Ali, additional, Zhu, Yangzhi, additional, Lee, Junmin, additional, Diltemiz, Sibel Emir, additional, Montazerian, Hossein, additional, Sangabathuni, Sivakoti, additional, Tavafoghi, Maryam, additional, Jucaud, Vadim, additional, Sun, Wujin, additional, Kim, Han‐Jun, additional, Ahadian, Samad, additional, and Khademhosseini, Ali, additional

Published
2021
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23. Recent developments in mussel-inspired materials for biomedical applications

Author

Barros, Natan Roberto, primary, Chen, Yi, additional, Hosseini, Vahid, additional, Wang, Weiyue, additional, Nasiri, Rohollah, additional, Mahmoodi, Mahboobeh, additional, Yalcintas, Ezgi Pinar, additional, Haghniaz, Reihaneh, additional, Mecwan, Marvin Magan, additional, Karamikamkar, Solmaz, additional, Dai, Wei, additional, Sarabi, Shima A., additional, Falcone, Natashya, additional, Young, Patric, additional, Zhu, Yangzhi, additional, Sun, Wujin, additional, Zhang, Shiming, additional, Lee, Junmin, additional, Lee, Kangju, additional, Ahadian, Samad, additional, Dokmeci, Mehmet Remzi, additional, Khademhosseini, Ali, additional, and Kim, Han-Jun, additional

Published
2021
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28. Development and evaluation of a novel approach to producing uniform 3-D tumor spheroid constructs

Author

Karamikamkar, Solmaz

Abstract

In vitro tumor spheroid models have been developed using microfluidic systems to generate 3-D hydrogel beads containing components of alginate and ECM protein, such as collagen, with high uniformity and throughput. During bead gelation, alginate acts as a fast gelling component helping to maintain the spherical shape of beads and to prevent adjacent or underlying beads from coalescing when working with the slower gelling temperature and pH-sensitivity of collagen components. There are also well-known limitations in using microfluidic systems when working with temperature-sensitive components of collagen type I, and it is determined that to produce uniform hydrogel droplets through a microfluidic system, the mixtures must be homogeneous. However, the issue of collagen’s sensitivity to temperature causes concern for chunks of collagen gel inside of the mixture before bead encapsulation; therefore causing the mixture to become non-uniform and risking chip clogging. In order to overcome this limitation, previous approaches have used a cooling system during bead encapsulation while tumor cells were also present in the mixture, but this procedure assisted in postponing collagen gelation prior to bead production and potentially contributing to a delay in cell proliferation. Here a novel yet simple method is developed to prepare homogeneous pre-bead-encapsulation-mixtures containing collagen through ultrasonication, while extending cell viability and proliferation. This method allows the cultivation of homogenous TS cultures with high uniformity and compact structure, and not only maintains cell viability but also stimulates the proliferation of cells in alginate/collagen hydrogel bead cultures. Depending on the sonication parameters, time and temperature, gelation of collagen is controlled by small sized fibrils to thick fibers. Human-source-Michigan-Cancer-Foundation-7 (MCF-7) cells isolated from a breast cancer cell line are successfully incorporated into alginate/collagen mixtures, followed by sonication, and then bead production. After bead gelation, the encapsulated MCF-7 cells remained viable and proliferated to form uniform TSs when the beads contained alginate and collagen. Results indicate that ultrasound treatment provides a powerful technique to change the structure of collagen from fiber to fibril, and to disperse collagen fibers in the mixture homogeneously for an application to generate uniform hydrogel beads and spheroids while not disturbing cell proliferation.

Published
2016
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29. A Review on Multifunctional Aerogel Fibers: Processing, Fabrication, Functionalization, and Applications

Author

Tafreshi, Omid Aghababaei, Mosanenzadeh, Shahriar Ghaffari, Karamikamkar, Solmaz, Saadatnia, Zia, Park, Chul B., and Naguib, Hani E.

Abstract

Aerogels have been frequently reported in three-dimensional (3D) monolith bulk, granule, and two-dimensional (2D) thin-film geometries. However, their commercialization has been widely restricted due to the lack of flexibility, extensibility, and fragile network structures. Recently, a new class of aerogels, i.e., aerogel fibers has emerged. When conventional aerogels are transformed into fibers (sub-micron or nanofibers), their performance may enhance remarkably. Therefore, such aerogel fibers can exhibit improved mechanical performance, favorable flexibility, higher tensile strength, and enhanced extensibility. This will make them a suitable candidate for applications that require high mechanical flexibility and to be stretchable. In conjunction with the superior thermal insulation performance of aerogels, aerogel fibers can be extensively used in other commercial sectors where load-bearing is crucial. In this short review, we intend to assess the current technologies for the production of aerogels in fiber geometry, called “aerogel fiber”. Materials used for this purpose, along with the post-processing and functionalization methods, are also evaluated. Their recent breakthroughs in emerging applications in a variety of engineering fields are covered. A discussion of current challenges, limitations, and the urgent need for the development of new technologies for the continuous production of aerogel fibers is provided. A road map pointing to a future direction in aerogel fiber field will be discussed.

Published
2021
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