29 results on '"Karam, Aimee N."'
Search Results
2. Age of onset and cumulative risk of mental disorders: a cross-national analysis of population surveys from 29 countries
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Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Alonso, Jordi, Altwaijri, Yasmin A., Andrade, Laura Helena, Atwoli, Lukoye, Benjet, Corina, Bromet, Evelyn J., Bruffaerts, Ronny, Bunting, Brendan, Caldas-de-Almeida, José Miguel, Cardoso, Graça, Chardoul, Stephanie, Cía, Alfredo H., Degenhardt, Louisa, De Girolamo, Giovanni, Gureje, Oye, Haro, Josep Maria, Harris, Meredith G., Hinkov, Hristo, Hu, Chi-yi, De Jonge, Peter, Karam, Aimee N., Karam, Elie G., Karam, Georges, Kazdin, Alan E., Kawakami, Norito, Kessler, Ronald C., Kiejna, Andrzej, Kovess-Masfety, Viviane, McGrath, John J., Medina-Mora, Maria Elena, Moskalewicz, Jacek, Navarro-Mateu, Fernando, Nishi, Daisuke, Piazza, Marina, Posada-Villa, José, Scott, Kate M., Stagnaro, Juan Carlos, Stein, Dan J., Ten Have, Margreet, Torres, Yolanda, Viana, Maria Carmen, Vigo, Daniel V., Vladescu, Cristian, Williams, David R., Woodruff, Peter, Wojtyniak, Bogdan, Xavier, Miguel, Zaslavsky, Alan M., McGrath, John J, Altwaijri, Yasmin, Andrade, Laura H, Bromet, Evelyn J, de Almeida, José Miguel Caldas, Chiu, Wai Tat, Demler, Olga V, Ferry, Finola, Karam, Elie G, Khaled, Salma M, Magno, Marta, Plana-Ripoll, Oleguer, Rapsey, Charlene, Sampson, Nancy A, Stein, Dan J, ten Have, Margreet, Woodruff, Peter W, Zarkov, Zahari, and Kessler, Ronald C
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- 2023
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3. Age of onset and cumulative risk of mental disorders: a cross-national analysis of population surveys from 29 countries
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McGrath, John J, primary, Al-Hamzawi, Ali, additional, Alonso, Jordi, additional, Altwaijri, Yasmin, additional, Andrade, Laura H, additional, Bromet, Evelyn J, additional, Bruffaerts, Ronny, additional, de Almeida, José Miguel Caldas, additional, Chardoul, Stephanie, additional, Chiu, Wai Tat, additional, Degenhardt, Louisa, additional, Demler, Olga V, additional, Ferry, Finola, additional, Gureje, Oye, additional, Haro, Josep Maria, additional, Karam, Elie G, additional, Karam, Georges, additional, Khaled, Salma M, additional, Kovess-Masfety, Viviane, additional, Magno, Marta, additional, Medina-Mora, Maria Elena, additional, Moskalewicz, Jacek, additional, Navarro-Mateu, Fernando, additional, Nishi, Daisuke, additional, Plana-Ripoll, Oleguer, additional, Posada-Villa, José, additional, Rapsey, Charlene, additional, Sampson, Nancy A, additional, Stagnaro, Juan Carlos, additional, Stein, Dan J, additional, ten Have, Margreet, additional, Torres, Yolanda, additional, Vladescu, Cristian, additional, Woodruff, Peter W, additional, Zarkov, Zahari, additional, Kessler, Ronald C, additional, Aguilar-Gaxiola, Sergio, additional, Altwaijri, Yasmin A., additional, Andrade, Laura Helena, additional, Atwoli, Lukoye, additional, Benjet, Corina, additional, Bromet, Evelyn J., additional, Bunting, Brendan, additional, Caldas-de-Almeida, José Miguel, additional, Cardoso, Graça, additional, Cía, Alfredo H., additional, De Girolamo, Giovanni, additional, Harris, Meredith G., additional, Hinkov, Hristo, additional, Hu, Chi-yi, additional, De Jonge, Peter, additional, Karam, Aimee N., additional, Karam, Elie G., additional, Kazdin, Alan E., additional, Kawakami, Norito, additional, Kessler, Ronald C., additional, Kiejna, Andrzej, additional, McGrath, John J., additional, Piazza, Marina, additional, Scott, Kate M., additional, Stein, Dan J., additional, Ten Have, Margreet, additional, Viana, Maria Carmen, additional, Vigo, Daniel V., additional, Williams, David R., additional, Woodruff, Peter, additional, Wojtyniak, Bogdan, additional, Xavier, Miguel, additional, and Zaslavsky, Alan M., additional
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- 2023
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4. Additional file 1 of Determinants of effective treatment coverage for posttraumatic stress disorder: findings from the World Mental Health Surveys
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Stein, Dan J., Kazdin, Alan E., Munthali, Richard J., Hwang, Irving, Harris, Meredith G., Alonso, Jordi, Andrade, Laura Helena, Bruffaerts, Ronny, Cardoso, Graça, Chardoul, Stephanie, de Girolamo, Giovanni, Florescu, Silvia, Gureje, Oye, Haro, Josep Maria, Karam, Aimee N., Karam, Elie G., Kovess-Masfety, Viviane, Lee, Sing, Medina-Mora, Maria Elena, Navarro-Mateu, Fernando, Posada-Villa, José, Stagnaro, Juan Carlos, ten Have, Margreet, Sampson, Nancy A., Kessler, Ronald C., and Vigo, Daniel V.
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Additional file 1: Supplemental Table 1. Bivariate predictors of effective coverage and its components among those with 12-Month posttraumatic stress disorder, in HICs countries (n=694)a. Supplemental Table 2. Multivariable model of effective coverage among those with 12-Month posttraumatic stress disorder, in high-income countries (n=694) a. Supplemental Table 3. Predictors of contact coverage among those with 12-Month posttraumatic stress disorder, in LMICs countries (n=220) a.
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- 2023
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5. An updated global picture of cigarette smoking persistence among adults
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Troost, Jonathan P., Barondess, David A., Storr, Carla L., Elisabeth Wells, J., Al-Hamzawi, Ali Obaid, Andrade, Laura Helena, Bromet, Evelyn, Bruffaerts, Ronny, Florescu, Silvia, Girolamo, Giovanni de, Graaf, Ron de, Gureje, Oye, Haro, Josep Maria, Hu, Chiyi, Huang, Yueqin, Karam, Aimee N., Kessler, Ronald C., Lepine, Jean-Pierre, Matschinger, Herbert, Medina-Mora, Maria Elena, O’Neill, Siobhan, Posada-Villa, Jose, Sagar, Rajesh, Takeshima, Tadashi, Tomov, Toma, Williams, David R., and Anthony, James C.
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- 2012
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6. Pre-marital predictors of marital violence in the WHO World Mental Health (WMH) Surveys
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Stokes, Cara M., Alonso, Jordi, Andrade, Laura Helena, Atwoli, Lukoye, Cardoso, Graça, Chiu, Wai Tat, Dinolova, Rumyana V., Gureje, Oye, Karam, Aimee N., Karam, Elie G., Kessler, Ronald C., Chatterji, Somnath, King, Andrew, Lee, Sing, Mneimneh, Zeina, Oladeji, Bibilola D., Petukhova, Maria, Rapsey, Charlene, Sampson, Nancy A., Scott, Kate, Street, Amy, Viana, Maria Carmen, Williams, Michelle A., Bossarte, Robert M., Aguilar-Gaxiola, Sergio, Al-Hamzawi, Ali, Al-Kaisy, Mohammed Salih, Benjet, Corina, Borges, Guilherme, Bromet, Evelyn J., Bruffaerts, Ronny, Bunting, Brendan, de Almeida, Jose Miguel Caldas, Cia, Alfredo H., Degenhardt, Louisa, Demyttenaere, Koen, Fayyad, John, Florescu, Silvia, de Girolamo, Giovanni, Haro, Josep Maria, He, Yanling, Hinkov, Hristo, Hu, Chi yi, Huang, Yueqin, de Jonge, Peter, Karam, Aimee Nasser, Kawakami, Norito, Kiejna, Andrzej, Kovess-Masfety, Viviane, Williams, David R., Developmental Psychology, and Scientific Visualization and Computer Graphics
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Adult ,Male ,medicine.medical_specialty ,Health (social science) ,Social Psychology ,Epidemiology ,Marital violence ,media_common.quotation_subject ,education ,Article ,03 medical and health sciences ,0302 clinical medicine ,Risk Factors ,Surveys and Questionnaires ,medicine ,Humans ,Wife ,Interpersonal Relations ,030212 general & internal medicine ,Marriage ,Spouses ,media_common ,Age at first marriage ,Public health ,social sciences ,Middle Aged ,Mental health ,Predictive modeling ,030227 psychiatry ,Intimate partner violence ,Psychiatry and Mental health ,Sexual intercourse ,International ,behavior and behavior mechanisms ,Domestic violence ,population characteristics ,Female ,Psychology ,Clinical psychology - Abstract
Purpose: Intimate partner violence (IPV) is a pervasive public health problem. Existing research has focused on reports from victims and few studies have considered pre-marital factors. The main objective of this study was to identify pre-marital predictors of IPV in the current marriage using information obtained from husbands and wives. Methods: Data from were obtained from married heterosexual couples in six countries. Potential predictors included demographic and relationship characteristics, adverse childhood experiences, dating violence, and psychiatric disorders. Reports of IPV and other characteristics from husbands and wives were considered independently and in relation to spousal reports. Results: Overall, 14.4% of women were victims of IPV in the current marriage. Analyses identified ten significant variables including age at first marriage (husband), education, relative number of previous marriages (wife), history of one or more categories of childhood adversity (husband or wife), history of dating violence (husband or wife), early initiation of sexual intercourse (husband or wife), and four combinations of internalizing and externalizing disorders. The final model was moderately predictive of marital violence, with the 5% of women accounting for 18.6% of all cases of marital IPV. Conclusions: Results from this study advance understanding of pre-marital predictors of IPV within current marriages, including the importance of considering differences in the experiences of partners prior to marriage and may provide a foundation for more targeted primary prevention efforts.
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- 2020
7. The epidemiology of anxiety disorders in the Arab world: A review
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Tanios, Christine Y., Abou-Saleh, Mohammad T., Karam, Aimée N., Salamoun, Mariana M., Mneimneh, Zeina N., and Karam, Elie G.
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- 2009
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8. CUMULATIVE TRAUMAS AND RISK THRESHOLDS: 12-MONTH PTSD IN THE WORLD MENTAL HEALTH (WMH) SURVEYS
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Karam, Elie G., Friedman, Matthew J., Hill, Eric D., Kessler, Ronald C., McLaughlin, Katie A., Petukhova, Maria, Sampson, Laura, Shahly, Victoria, Angermeyer, Matthias C., Bromet, Evelyn J., de Girolamo, Giovanni, de Graaf, Ron, Demyttenaere, Koen, Ferry, Finola, Florescu, Silvia E., Haro, Josep Maria, He, Yanling, Karam, Aimee N., Kawakami, Norito, Kovess-Masfety, Viviane, Elena Medina-Mora, María, Browne, Mark A. Oakley, Posada-Villa, José A., Shalev, Arieh Y., Stein, Dan J., Viana, Maria Carmen, Zarkov, Zahari, and Koenen, Karestan C.
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- 2014
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9. Lifetime prevalence of mental disorders in Lebanon: first onset, treatment, and exposure to war
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Karam, Elie G., Mneimneh, Zeina N., Dimassi, Hani, Fayyad, John A., Karam, Aimee N., Nasser, Soumana C., Chatterji, Somnath, and Kessler, Ronald C.
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Biological sciences - Abstract
Background There are no published data on national lifetime prevalence and treatment of mental disorders in the Arab region. Furthermore, the effect of war on first onset of disorders has not been addressed previously on a national level, especially in the Arab region. Thus, the current study aims at investigating the lifetime prevalence, treatment, age of onset of mental disorders, and their relationship to war in Lebanon. Methods and Findings The Lebanese Evaluation of the Burden of Ailments and Needs Of the Nation study was carried out on a nationally representative sample of the Lebanese population (n=2,857 adults). Respondents were interviewed using the fully structured WHO Composite International Diagnostic Interview 3.0. Lifetime prevalence of any Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) disorder was 25.8%. Anxiety (16.7%) and mood (12.6%) were more common than impulse control (4.4%) and substance (2.2%) disorders. Only a minority of people with any mental disorder ever received professional treatment, with substantial delays (6 to 28 y) between the onset of disorders and onset of treatment. War exposure increased the risk of first onset of anxiety (odds ratio [OR] 5.92, 95% confidence interval [CI] 2.5-14.1), mood (OR 3.32, 95% CI 2.0-5.6), and impulse control disorders (OR 12.72, 95% CI 4.5-35.7). Conclusions About one-fourth of the sample (25.8%) met criteria for at least one of the DSM-IV disorders at some point in their lives. There is a substantial unmet need for early identification and treatment. Exposure to war events increases the odds of first onset of mental disorders., Introduction Large-scale psychiatric epidemiologic studies have become increasingly common in industrialized countries in the past decade [1-5] in response to mounting concerns about the prevalence and burden of mental disorders [...]
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- 2008
10. Prevalence and treatment of mental disorders in Lebanon: a national epidemiological survey
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Karam, Elie G., Mneimneh, Zeina N., Karam, Aimee N., Fayyad, John A., Nasser, Soumana C., Chatterji, Somnath, and Kessler, Ronald C.
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Epidemiology -- Demographic aspects ,Mental illness -- Care and treatment ,Mental illness -- Demographic aspects - Published
- 2006
11. Temperament and major depressive disorder
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Mneimneh Zeina, Yeretzian Joumana S, Salamoun Mariana M, Karam Elie G, Karam Aimee N, and Fayyad John
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Psychiatry ,RC435-571 - Published
- 2010
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12. Associations of serious mental illness with earnings: results from the WHO World Mental Health surveys
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Levinson, Daphna, Lakoma, Matthew D., Petukhova, Maria, Schoenbaum, Michael, Zaslavsky, Alan M., Angermeyer, Matthias, Borges, Guilherme, Bruffaerts, Ronny, de Girolamo, Giovanni, de Graaf, Ron, Gureje, Oye, Haro, Josep Maria, Hu, Chiyi, Karam, Aimee N., Kawakami, Norito, Lee, Sing, Lepine, Jean-Pierre, Browne, Mark Oakley, Okoliyski, Michail, Posada-Villa, José, Sagar, Rajesh, Viana, Maria Carmen, Williams, David R., and Kessler, Ronald C.
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- 2010
13. AGE DIFFERENCES IN THE PREVALENCE AND CO-MORBIDITY OF DSM-IV MAJOR DEPRESSIVE EPISODES: RESULTS FROM THE WHO WORLD MENTAL HEALTH SURVEY INITIATIVE
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Kessler, Ronald C., Birnbaum, Howard G., Shahly, Victoria, Bromet, Evelyn, Hwang, Irving, McLaughlin, Katie A., Sampson, Nancy, Andrade, Laura Helena, de Girolamo, Giovanni, Demyttenaere, Koen, Haro, Josep Maria, Karam, Aimee N., Kostyuchenko, Stanislav, Kovess, Viviane, Lara, Carmen, Levinson, Daphna, Matschinger, Herbert, Nakane, Yoshibumi, Browne, Mark Oakley, Ormel, Johan, Posada-Villa, Jose, Sagar, Rajesh, and Stein, Dan J.
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- 2010
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14. Patterns and correlates of patient‐reported helpfulness of treatment for common mental and substance use disorders in the WHOWorld Mental Health Surveys
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Kessler, Ronald C., Kazdin, Alan E., Aguilar‐Gaxiola, Sergio, Al‐Hamzawi, Ali, Alonso, Jordi, Altwaijri, Yasmin A., Andrade, Laura H., Benjet, Corina, Bharat, Chrianna, Borges, Guilherme, Bruffaerts, Ronny, Bunting, Brendan, Almeida, José Miguel Caldas, Cardoso, Graça, Chiu, Wai Tat, Cía, Alfredo, Ciutan, Marius, Degenhardt, Louisa, Girolamo, Giovanni, Jonge, Peter, Vries, Ymkje Anna, Florescu, Silvia, Gureje, Oye, Haro, Josep Maria, Harris, Meredith G., Hu, Chiyi, Karam, Aimee N., Karam, Elie G., Karam, Georges, Kawakami, Norito, Kiejna, Andrzej, Kovess‐Masfety, Viviane, Lee, Sing, Makanjuola, Victor, McGrath, John J., Medina‐Mora, Maria Elena, Moskalewicz, Jacek, Navarro‐Mateu, Fernando, Nierenberg, Andrew A., Nishi, Daisuke, Ojagbemi, Akin, Oladeji, Bibilola D., O'Neill, Siobhan, Posada‐Villa, José, Puac‐Polanco, Victor, Rapsey, Charlene, Ruscio, Ayelet Meron, Sampson, Nancy A., Scott, Kate M., Slade, Tim, Stagnaro, Juan Carlos, Stein, Dan J., Tachimori, Hisateru, Have, Margreet, Torres, Yolanda, Viana, Maria Carmen, Vigo, Daniel V., Williams, David R., Wojtyniak, Bogdan, Xavier, Miguel, Zarkov, Zahari, and Ziobrowski, Hannah N.
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Patient‐reported helpfulness of treatment is an important indicator of quality in patient‐centered care. We examined its pathways and predictors among respondents to household surveys who reported ever receiving treatment for major depression, generalized anxiety disorder, social phobia, specific phobia, post‐traumatic stress disorder, bipolar disorder, or alcohol use disorder. Data came from 30 community epidemiological surveys – 17 in high‐income countries (HICs) and 13 in low‐ and middle‐income countries (LMICs) – carried out as part of the World Health Organization (WHO)’s World Mental Health (WMH) Surveys. Respondents were asked whether treatment of each disorder was ever helpful and, if so, the number of professionals seen before receiving helpful treatment. Across all surveys and diagnostic categories, 26.1% of patients (N=10,035) reported being helped by the very first professional they saw. Persisting to a second professional after a first unhelpful treatment brought the cumulative probability of receiving helpful treatment to 51.2%. If patients persisted with up through eight professionals, the cumulative probability rose to 90.6%. However, only an estimated 22.8% of patients would have persisted in seeing these many professionals after repeatedly receiving treatments they considered not helpful. Although the proportion of individuals with disorders who sought treatment was higher and they were more persistent in HICs than LMICs, proportional helpfulness among treated cases was no different between HICs and LMICs. A wide range of predictors of perceived treatment helpfulness were found, some of them consistent across diagnostic categories and others unique to specific disorders. These results provide novel information about patient evaluations of treatment across diagnoses and countries varying in income level, and suggest that a critical issue in improving the quality of care for mental disorders should be fostering persistence in professional help‐seeking if earlier treatments are not helpful.
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- 2022
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15. Cross-national epidemiology of DSM-IV major depressive episode
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Matschinger Herbert, Levinson Daphna, Lépine Jean-Pierre, Kaur Jagdish, Kostyuchenko Stanislav, Karam Aimee N, Iwata Noboru, Hu Chiyi, Demyttenaere Koen, de Graaf Ron, de Girolamo Giovanni, Alonso Jordi, Sampson Nancy A, Hwang Irving, Bromet Evelyn, Andrade Laura, Mora Maria, Browne Mark, Posada-Villa Jose, Viana Maria, Williams David R, and Kessler Ronald C
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Medicine - Abstract
Abstract Background Major depression is one of the leading causes of disability worldwide, yet epidemiologic data are not available for many countries, particularly low- to middle-income countries. In this paper, we present data on the prevalence, impairment and demographic correlates of depression from 18 high and low- to middle-income countries in the World Mental Health Survey Initiative. Methods Major depressive episodes (MDE) as defined by the Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DMS-IV) were evaluated in face-to-face interviews using the World Health Organization Composite International Diagnostic Interview (CIDI). Data from 18 countries were analyzed in this report (n = 89,037). All countries surveyed representative, population-based samples of adults. Results The average lifetime and 12-month prevalence estimates of DSM-IV MDE were 14.6% and 5.5% in the ten high-income and 11.1% and 5.9% in the eight low- to middle-income countries. The average age of onset ascertained retrospectively was 25.7 in the high-income and 24.0 in low- to middle-income countries. Functional impairment was associated with recency of MDE. The female: male ratio was about 2:1. In high-income countries, younger age was associated with higher 12-month prevalence; by contrast, in several low- to middle-income countries, older age was associated with greater likelihood of MDE. The strongest demographic correlate in high-income countries was being separated from a partner, and in low- to middle-income countries, was being divorced or widowed. Conclusions MDE is a significant public-health concern across all regions of the world and is strongly linked to social conditions. Future research is needed to investigate the combination of demographic risk factors that are most strongly associated with MDE in the specific countries included in the WMH.
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- 2011
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16. Outcome of depression and anxiety after war
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Dimassi, Hani, Karam, Elie G., Karam, Aimee N., Melhem, Nadine, Mneimneh, Zeina, Tabet, Caroline Cordahi, Dimassi, Hani, Karam, Elie G., Karam, Aimee N., Melhem, Nadine, Mneimneh, Zeina, and Tabet, Caroline Cordahi
- Abstract
Prospective studies of children exposed to war have not investigated disorders other than posttraumatic stress disorder (PTSD) and have methodological limitations. From a stratified random sample of 386 children and adolescents who had been interviewed 3 weeks after war exposure (Phase 1) a random subsample (N = 143) was interviewed a year later (Phase 2). PTSD, major depressive disorder (MDD), separation anxiety disorder (SAD), overanxious disorder (OAD), and psychosocial stressors were assessed using structured interviews administered to both children and adolescents and their parents. The prevalence of disorders among the 143 at Phase 1 was MDD 25.9%, SAD 16.1%, OAD 28.0%, and PTSD 26.0%, with 44.1% having any disorder. At Phase 2 the prevalence was MDD, 5.6%; SAD, 4.2%; OAD, 0%; and PTSD, 1.4%, with 9.2% having any disorder. Occurrence of disorders at Phase 1 was associated with older age, prewar disorders, financial problems, fear of being beaten, and witnessing any war event (ORs ranged from 2.5 to 28.6). Persistence of disorders to Phase 2 was associated with prewar disorders (OR = 6.0) and witnessing any war event (OR = 14.3). There are implications for detection of at-risk cases following wars by screening for adolescents exposed to family violence, those with prewar disorders, and those who directly witnessed war events to target them for specific interventions.
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- 2017
17. Lifetime prevalence of mental disorders in Lebanon
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Dimassi, Hani, Karam, Elie G., Mneimneh, Zeina N., Fayyad, John A., Karam, Aimee N., Nasser, Soumana C., Kessler, Ronald C., Dimassi, Hani, Karam, Elie G., Mneimneh, Zeina N., Fayyad, John A., Karam, Aimee N., Nasser, Soumana C., and Kessler, Ronald C.
- Abstract
Background There are no published data on national lifetime prevalence and treatment of mental disorders in the Arab region. Furthermore, the effect of war on first onset of disorders has not been addressed previously on a national level, especially in the Arab region. Thus, the current study aims at investigating the lifetime prevalence, treatment, age of onset of mental disorders, and their relationship to war in Lebanon. Methods and Findings The Lebanese Evaluation of the Burden of Ailments and Needs Of the Nation study was carried out on a nationally representative sample of the Lebanese population (n = 2,857 adults). Respondents were interviewed using the fully structured WHO Composite International Diagnostic Interview 3.0. Lifetime prevalence of any Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) disorder was 25.8%. Anxiety (16.7%) and mood (12.6%) were more common than impulse control (4.4%) and substance (2.2%) disorders. Only a minority of people with any mental disorder ever received professional treatment, with substantial delays (6 to 28 y) between the onset of disorders and onset of treatment. War exposure increased the risk of first onset of anxiety (odds ratio [OR] 5.92, 95% confidence interval [CI] 2.5–14.1), mood (OR 3.32, 95% CI 2.0–5.6), and impulse control disorders (OR 12.72, 95% CI 4.5–35.7). Conclusions About one-fourth of the sample (25.8%) met criteria for at least one of the DSM-IV disorders at some point in their lives. There is a substantial unmet need for early identification and treatment. Exposure to war events increases the odds of first onset of mental disorders.
- Published
- 2015
18. CUMULATIVE TRAUMAS AND RISK THRESHOLDS: 12-MONTH PTSD IN THE WORLD MENTAL HEALTH (WMH) SURVEYS
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Karam, Elie G., Friedman, Matthew J., Hill, Eric D., Kessler, Ronald C., McLaughlin, Katie A., Petukhova, Maria, Sampson, Laura, Shahly, Victoria, Angermeyer, Matthias C., Bromet, Evelyn J., de Girolamo, Giovanni, de Graaf, Ron, Demyttenaere, Koen, Ferry, Finola, Florescu, Silvia E., Haro, Josep Maria, He, Yanling, Karam, Aimee N., Kawakami, Norito, Kovess-Masfety, Viviane, Medina-Mora, María Elena, Browne, Mark A. Oakley, Posada-Villa, José A., Shalev, Arieh Y., Stein, Dan J., Viana, Maria Carmen, Zarkov, Zahari, and Koenen, Karestan C.
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Adult ,Male ,Internationality ,Adolescent ,Mental Disorders ,Comorbidity ,Health Surveys ,Article ,United States ,Europe ,Life Change Events ,Stress Disorders, Post-Traumatic ,Young Adult ,Risk Factors ,Prevalence ,Humans ,Female ,Age of Onset ,Child ,Stress, Psychological - Abstract
Clinical research suggests that posttraumatic stress disorder (PTSD) patients exposed to multiple traumatic events (TEs) rather than a single TE have increased morbidity and dysfunction. Although epidemiological surveys in the United States and Europe also document high rates of multiple TE exposure, no population-based cross-national data have examined this issue.Data were analyzed from 20 population surveys in the World Health Organization World Mental Health Survey Initiative (n = 51,295 aged 18+). The Composite International Diagnostic Interview (3.0) assessed 12-month PTSD and other common DSM-IV disorders. Respondents with 12-month PTSD were assessed for single versus multiple TEs implicated in their symptoms. Associations were examined with age of onset (AOO), functional impairment, comorbidity, and PTSD symptom counts.19.8% of respondents with 12-month PTSD reported that their symptoms were associated with multiple TEs. Cases who associated their PTSD with four or more TEs had greater functional impairment, an earlier AOO, longer duration, higher comorbidity with mood and anxiety disorders, elevated hyperarousal symptoms, higher proportional exposures to partner physical abuse and other types of physical assault, and lower proportional exposure to unexpected death of a loved one than cases with fewer associated TEs.A risk threshold was observed in this large-scale cross-national database wherein cases who associated their PTSD with four or more TEs presented a more "complex" clinical picture with substantially greater functional impairment and greater morbidity than other cases of PTSD. PTSD cases associated with four or more TEs may merit specific and targeted intervention strategies.
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- 2013
19. Including information about comorbidity in estimates of disease burden: Results from the WHO World Mental Health Surveys
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Alonso, Jordi, Vilagut, Gemma, Chatterji, Somnath, Heeringa, Steven, Schoenbaum, Michael, Üstün, T. Bedirhan, Rojas-Farreras, Sonia, Angermeyer, Matthias, Bromet, Evelyn, Bruffaerts, Ronny, de Girolamo, Giovanni, Gureje, Oye, Haro, Josep Maria, Karam, Aimee N., Kovess, Viviane, Levinson, Daphna, Liu, Zhaorui, Mora, Maria Elena Medina, Ormel, J., Posada-Villa, Jose, Uda, Hidenori, and Kessler, Ronald C.
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Adult ,Cross-Cultural Comparison ,Male ,Adolescent ,Comorbidity ,World Health Organization ,Article ,Young Adult ,Cost of Illness ,Universal Health Insurance ,Sleep Initiation and Maintenance Disorders ,Health Status Indicators ,Humans ,Aged ,Pain Measurement ,Aged, 80 and over ,Analysis of Variance ,Depressive Disorder, Major ,Health Care Rationing ,Health Policy ,Mental Disorders ,Middle Aged ,Health Surveys ,Chronic Disease ,Female ,Nervous System Diseases - Abstract
The methodology commonly used to estimate disease burden, featuring ratings of severity of individual conditions, has been criticized for ignoring co-morbidity. A methodology that addresses this problem is proposed and illustrated here with data from the World Health Organization World Mental Health Surveys. Although the analysis is based on self-reports about one's own conditions in a community survey, the logic applies equally well to analysis of hypothetical vignettes describing co-morbid condition profiles.Face-to-face interviews in 13 countries (six developing, nine developed; n=31 067; response rate=69.6%) assessed 10 classes of chronic physical and nine of mental conditions. A visual analog scale (VAS) was used to assess overall perceived health. Multiple regression analysis with interactions for co-morbidity was used to estimate associations of conditions with VAS. Simulation was used to estimate condition-specific effects.The best-fitting model included condition main effects and interactions of types by numbers of conditions. Neurological conditions, insomnia and major depression were rated most severe. Adjustment for co-morbidity reduced condition-specific estimates with substantial between-condition variation (0.24-0.70 ratios of condition-specific estimates with and without adjustment for co-morbidity). The societal-level burden rankings were quite different from the individual-level rankings, with the highest societal-level rankings associated with conditions having high prevalence rather than high individual-level severity.Plausible estimates of disorder-specific effects on VAS can be obtained using methods that adjust for co-morbidity. These adjustments substantially influence condition-specific ratings.
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- 2010
20. Outcome of Depression and Anxiety After War: A Prospective Epidemiologic Study of Children and Adolescents
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Karam, Elie G., primary, Fayyad, John, additional, Karam, Aimee N., additional, Melhem, Nadine, additional, Mneimneh, Zeina, additional, Dimassi, Hani, additional, and Tabet, Caroline Cordahi, additional
- Published
- 2014
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21. CUMULATIVE TRAUMAS AND RISK THRESHOLDS: 12-MONTH PTSD IN THE WORLD MENTAL HEALTH (WMH) SURVEYS
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Karam, Elie G., primary, Friedman, Matthew J., additional, Hill, Eric D., additional, Kessler, Ronald C., additional, McLaughlin, Katie A., additional, Petukhova, Maria, additional, Sampson, Laura, additional, Shahly, Victoria, additional, Angermeyer, Matthias C., additional, Bromet, Evelyn J., additional, de Girolamo, Giovanni, additional, de Graaf, Ron, additional, Demyttenaere, Koen, additional, Ferry, Finola, additional, Florescu, Silvia E., additional, Haro, Josep Maria, additional, He, Yanling, additional, Karam, Aimee N., additional, Kawakami, Norito, additional, Kovess-Masfety, Viviane, additional, Medina-Mora, María Elena, additional, Browne, Mark A. Oakley, additional, Posada-Villa, José A., additional, Shalev, Arieh Y., additional, Stein, Dan J., additional, Viana, Maria Carmen, additional, Zarkov, Zahari, additional, and Koenen, Karestan C., additional
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- 2013
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22. Cross-national epidemiology of DSM-IV major depressive episode
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Bromet, Evelyn, primary, Andrade, Laura Helena, additional, Hwang, Irving, additional, Sampson, Nancy A, additional, Alonso, Jordi, additional, de Girolamo, Giovanni, additional, de Graaf, Ron, additional, Demyttenaere, Koen, additional, Hu, Chiyi, additional, Iwata, Noboru, additional, Karam, Aimee N, additional, Kaur, Jagdish, additional, Kostyuchenko, Stanislav, additional, Lépine, Jean-Pierre, additional, Levinson, Daphna, additional, Matschinger, Herbert, additional, Mora, Maria Elena Medina, additional, Browne, Mark Oakley, additional, Posada-Villa, Jose, additional, Viana, Maria Carmen, additional, Williams, David R, additional, and Kessler, Ronald C, additional
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- 2011
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23. The role of anxious and hyperthymic temperaments in mental disorders: a national epidemiologic study
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KARAM, ELIE G., primary, SALAMOUN, MARIANA M., additional, YERETZIAN, JOUMANA S., additional, MNEIMNEH, ZEINA N., additional, KARAM, AIMEE N., additional, FAYYAD, JOHN, additional, HANTOUCHE, ELIE, additional, AKISKAL, KAREEN, additional, and AKISKAL, HAGOP S., additional
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- 2010
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24. Temperament and major depressive disorder
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Karam, Elie G, primary, Salamoun, Mariana M, additional, Yeretzian, Joumana S, additional, Mneimneh, Zeina, additional, Karam, Aimee N, additional, and Fayyad, John, additional
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- 2010
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25. Evaluating the drug use “gateway” theory using cross-national data: Consistency and associations of the order of initiation of drug use among participants in the WHO World Mental Health Surveys
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Degenhardt, Louisa, primary, Dierker, Lisa, additional, Chiu, Wai Tat, additional, Medina-Mora, Maria Elena, additional, Neumark, Yehuda, additional, Sampson, Nancy, additional, Alonso, Jordi, additional, Angermeyer, Matthias, additional, Anthony, James C., additional, Bruffaerts, Ronny, additional, de Girolamo, Giovanni, additional, de Graaf, Ron, additional, Gureje, Oye, additional, Karam, Aimee N., additional, Kostyuchenko, Stanislav, additional, Lee, Sing, additional, Lépine, Jean-Pierre, additional, Levinson, Daphna, additional, Nakamura, Yosikazu, additional, Posada-Villa, Jose, additional, Stein, Dan, additional, Wells, J. Elisabeth, additional, and Kessler, Ronald C., additional
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- 2010
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26. Prevalence, Severity, and Unmet Need for Treatment of Mental Disorders in the World Health Organization World Mental Health Surveys.
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Demyttenaere, Koen, Bruffaerts, Ronny, Posada-Villa, Jose, Gasquet, Isabelle, Kovess, Viviane, Lepine, Jean Pierre, Angemeyer, Mathias C., Bernert, Sebastian, De Girolamo, Giovanni, Morosini, Pierluigi, Polidori, Gabriella, Kikkawa, Takehiko, Kawakami, Norito, Ono, Yutaka, Takeshima, Tadashi, Uda, Hidenori, Karam, Elie G., Fayyad, John A., Karam, Aimee N., and Mneimneh, Zeina N.
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MENTAL illness ,SURVEYS ,INTERNATIONAL cooperation on public health ,WORLD health ,HEALTH outcome assessment ,PSYCHIATRIC diagnosis ,PUBLIC health surveillance ,INTERNATIONAL cooperation - Abstract
Context Little is known about the extent or severity of untreated mental disorders, especially in less-developed countries. Objective To estimate prevalence, severity, and treatment of Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) mental disorders in 14 countries (6 less developed, 8 developed) in the World Health Organization (WHO) World Mental Health (WMH) Survey Initiative. Design, Setting, and Participants Face-to-face household surveys of 60 463 community adults conducted from 2001-2003 in 14 countries in the Americas, Europe, the Middle East, Africa, and Asia. Main Outcome Measures The DSM-IV disorders, severity, and treatment were assessed with the WMH version of the WHO Composite International Diagnostic Interview (WMH-CIDI), a fully structured, lay-administered psychiatric diagnostic interview. Results The prevalence of having any WMH-CIDI/DSM-IV disorder in the prior year varied widely, from 4.3% in Shanghai to 26.4% in the United States, with an interquartile range (IQR) of 9.1%-16.9%. Between 33.1% (Colombia) and 80.9% (Nigeria) of 12-month cases were mild (IQR, 40.2%-53.3%). Serious disorders were associated with substantial role disability. Although disorder severity was correlated with probability of treatment in almost all countries, 35.5% to 50.3% of serious cases in developed countries and 76.3% to 85.4% in less-developed countries received no treatment in the 12 months before the interview. Due to the high prevalence of mild and subthreshold cases, the number of those who received treatment far exceeds the number of untreated serious cases in every country. Conclusions Reallocation of treatment resources could substantially decrease the problem of unmet need for treatment of mental disorders among serious cases. Structural barriers exist to this reallocation. Careful consideration needs to be given to the value of treating some mild cases, especially those at risk for progressing to more serious disorders. [ABSTRACT FROM AUTHOR]
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- 2004
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27. Lifetime Prevalence of Mental Disorders in Lebanon: First Onset, Treatment, and Exposure to War
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Dimassi, Hani, Chatterji, Somnath, Karam, Elie G., Mneimneh, Zeina N., Fayyad, John A., Karam, Aimee N., Nasser, Soumana C., and Kessler, Ronald
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mental health ,psychiatry ,public health - Abstract
Background: There are no published data on national lifetime prevalence and treatment of mental disorders in the Arab region. Furthermore, the effect of war on first onset of disorders has not been addressed previously on a national level, especially in the Arab region. Thus, the current study aims at investigating the lifetime prevalence, treatment, age of onset of mental disorders, and their relationship to war in Lebanon. Methods and Findings: The Lebanese Evaluation of the Burden of Ailments and Needs Of the Nation study was carried out on a nationally representative sample of the Lebanese population (n = 2,857 adults). Respondents were interviewed using the fully structured WHO Composite International Diagnostic Interview 3.0. Lifetime prevalence of any Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) disorder was 25.8%. Anxiety (16.7%) and mood (12.6%) were more common than impulse control (4.4%) and substance (2.2%) disorders. Only a minority of people with any mental disorder ever received professional treatment, with substantial delays (6 to 28 y) between the onset of disorders and onset of treatment. War exposure increased the risk of first onset of anxiety (odds ratio [OR] 5.92, 95% confidence interval [CI] 2.5–14.1), mood (OR 3.32, 95% CI 2.0–5.6), and impulse control disorders (OR 12.72, 95% CI 4.5–35.7). Conclusions: About one-fourth of the sample (25.8%) met criteria for at least one of the DSM-IV disorders at some point in their lives. There is a substantial unmet need for early identification and treatment. Exposure to war events increases the odds of first onset of mental disorders.
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- 2008
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28. Perceived helpfulness of treatment for alcohol use disorders: Findings from the World Mental Health Surveys.
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Degenhardt, Louisa, Bharat, Chrianna, Chiu, Wai Tat, Harris, Meredith G., Kazdin, Alan E., Vigo, Daniel V., Sampson, Nancy A., Alonso, Jordi, Andrade, Laura Helena, Bruffaerts, Ronny, Bunting, Brendan, Cardoso, Graça, de Girolamo, Giovanni, Florescu, Silvia, Gureje, Oye, Haro, Josep Maria, Hu, Chiyi, Karam, Aimee N., Karam, Elie G., and Kovess-Masfety, Viviane
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MENTAL health surveys , *ALCOHOLISM , *WORLD health , *ADULTS , *CONDITIONAL probability - Abstract
We examined prevalence and factors associated with receiving perceived helpful alcohol use disorder (AUD) treatment, and persistence in help-seeking after earlier unhelpful treatment. Data came from 27 community epidemiologic surveys of adults in 24 countries using the World Health Organization World Mental Health surveys (n = 93,843). Participants with a lifetime history of treated AUD were asked if they ever received helpful AUD treatment, and how many professionals they had talked to up to and including the first time they received helpful treatment (or how many ever, if they had not received helpful treatment). 11.8% of respondents with lifetime AUD reported ever obtaining treatment (n = 9378); of these, 44% reported that treatment was helpful. The probability of obtaining helpful treatment from the first professional seen was 21.8%; the conditional probability of subsequent professionals being helpful after earlier unhelpful treatment tended to decrease as more professionals were seen. The cumulative probability of receiving helpful treatment at least once increased from 21.8% after the first professional to 79.7% after the seventh professional seen, following earlier unhelpful treatment. However, the cumulative probability of persisting with up to seven professionals in the face of prior treatments being unhelpful was only 13.2%. Fewer than half of people with AUDs who sought treatment found treatment helpful; the most important factor was persistence in seeking further treatment if a previous professional had not helped. Future research should examine how to increase the likelihood that AUD treatment is found to be helpful on any given contact. • Examined receipt of helpful AUD treatment in adult community surveys in 24 countries • 11.8% of respondents with lifetime AUD reported ever obtaining AUD treatment • 44% ever obtaining treatment reported that it was helpful • Probability of obtaining helpful treatment from the 1st professional seen was 21.8% • 79.7% could receive helpful treatment if persevering to see seven professionals [ABSTRACT FROM AUTHOR]
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- 2021
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29. Patterns and correlates of patient-reported helpfulness of treatment for common mental and substance use disorders in the WHO World Mental Health Surveys.
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Kessler RC, Kazdin AE, Aguilar-Gaxiola S, Al-Hamzawi A, Alonso J, Altwaijri YA, Andrade LH, Benjet C, Bharat C, Borges G, Bruffaerts R, Bunting B, de Almeida JMC, Cardoso G, Chiu WT, Cía A, Ciutan M, Degenhardt L, de Girolamo G, de Jonge P, de Vries YA, Florescu S, Gureje O, Haro JM, Harris MG, Hu C, Karam AN, Karam EG, Karam G, Kawakami N, Kiejna A, Kovess-Masfety V, Lee S, Makanjuola V, McGrath JJ, Medina-Mora ME, Moskalewicz J, Navarro-Mateu F, Nierenberg AA, Nishi D, Ojagbemi A, Oladeji BD, O'Neill S, Posada-Villa J, Puac-Polanco V, Rapsey C, Ruscio AM, Sampson NA, Scott KM, Slade T, Stagnaro JC, Stein DJ, Tachimori H, Ten Have M, Torres Y, Viana MC, Vigo DV, Williams DR, Wojtyniak B, Xavier M, Zarkov Z, and Ziobrowski HN
- Abstract
Patient-reported helpfulness of treatment is an important indicator of quality in patient-centered care. We examined its pathways and predictors among respondents to household surveys who reported ever receiving treatment for major depression, generalized anxiety disorder, social phobia, specific phobia, post-traumatic stress disorder, bipolar disorder, or alcohol use disorder. Data came from 30 community epidemiological surveys - 17 in high-income countries (HICs) and 13 in low- and middle-income countries (LMICs) - carried out as part of the World Health Organization (WHO)'s World Mental Health (WMH) Surveys. Respondents were asked whether treatment of each disorder was ever helpful and, if so, the number of professionals seen before receiving helpful treatment. Across all surveys and diagnostic categories, 26.1% of patients (N=10,035) reported being helped by the very first professional they saw. Persisting to a second professional after a first unhelpful treatment brought the cumulative probability of receiving helpful treatment to 51.2%. If patients persisted with up through eight professionals, the cumulative probability rose to 90.6%. However, only an estimated 22.8% of patients would have persisted in seeing these many professionals after repeatedly receiving treatments they considered not helpful. Although the proportion of individuals with disorders who sought treatment was higher and they were more persistent in HICs than LMICs, proportional helpfulness among treated cases was no different between HICs and LMICs. A wide range of predictors of perceived treatment helpfulness were found, some of them consistent across diagnostic categories and others unique to specific disorders. These results provide novel information about patient evaluations of treatment across diagnoses and countries varying in income level, and suggest that a critical issue in improving the quality of care for mental disorders should be fostering persistence in professional help-seeking if earlier treatments are not helpful., (© 2022 World Psychiatric Association.)
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- 2022
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