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This study aims to examine the potential differences between teacher evaluations and artificial intelligence (AI) tool-based assessment systems in university examinations. The research has evaluated a wide spectrum of exams including numerical and verbal course exams, exams with different assessment styles (project, test exam, traditional exam), and both theoretical and practical course exams. These exams were selected using a criterion sampling method and were analyzed using Bland-Altman Analysis and Intraclass Correlation Coefficient (ICC) analyses to assess how AI and teacher evaluations performed across a broad range. The research findings indicate that while there is a high level of proficiency between the total exam scores assessed by artificial intelligence and teacher evaluations; medium consistency was found in the evaluation of visually based exams, low consistency in video exams, high consistency in test exams, and low consistency in traditional exams. This research is crucial as it helps to identify specific areas where artificial intelligence can either complement or needs improvement in educational assessment, guiding the development of more accurate and fair evaluation tools.

The first step to access information; it is possible to perceive it by hearing, seeing and touching. It is necessary to make sense of this gained knowledge. Therefore, having some basic skills forms the basis of all disciplines. The purpose of this research is to determine skills through activities prepared with an interdisciplinary approach. The research was designed as a case study. Purposeful sampling method was used to determine the study group of the research; the study was conducted with third grade primary school teaching students as the study group. As data collection tools in the study; skill target list, in-class skill observation form, semi-structured interview form and student products were used. At the end of the research, the students' skills were determined and in terms of science skills; it was revealed that life skills and innovative thinking skills were sufficient, but scientific process skills were not sufficient. In terms of language skills, reading and writing skills were found to be at an intermediate level. However, speaking skills, which are self-expression skills, were found to be at a low level. In terms of mathematical skills, it was observed that their problem solving skills were high, but their level of using basic mathematical skills was low. Technology skills; it has been found that it is sufficient in terms of algorithm creation, but not in the context of science acquisition. In addition, it has been observed that the activities prepared through the task-oriented teaching method make the lesson interesting and are effective in revealing creativity.

This study investigated the effect of the use of content-specific material-based activities on children's mathematical skills, and changes in emotions for both sides with the help of math workstations to serve as responsive partners in delivering quality mathematics education to children and teachers. A total of 20 female kindergarten teachers and 625 children (female= 393, male=232, M = 64.57 months) studying in classes with disadvantages pertaining to materials participated in the study. The study used a fully mixed sequential equal status design, and quantitative data was analyzed using ANOVA and multilevel regression, while inductive content analysis was used to analyze qualitative data. The study found that teachers' development of facilitating alternative perspectives towards mathematics mitigated negative beliefs related to emotions arising from teachers' and children's negative experiences with mathematics. This study re-emphasizes the significance of emotional circumstances for learning mathematics in early childhood education, and teachers need game-based, effective, and innovative pedagogical approaches without prioritizing academic concerns.

The aim of this study is to compare the neurological status, developmental parameters and physical fitness of children who engage in regular physical activity in the preschool period versus those who do not. The study included 305 healthy children aged 4-6 years, consisting of 154 girls and 151 boys. In addition to evaluating the demographic characteristics of children; Touwen Neurological Examination, Denver Developmental Screening Test (DDST) II, and Preschool Physical Fitness (PREFIT) test battery were used to assess neurological status, developmental parameters, and physical fitness, respectively. A statistically significant difference was found between neurological status (p = 0.046), developmental parameters (p = 0.000) and physical fitness (Standing Long Jump (p = 0.008), handgrip (p = 0.006)) of preschool children who engaged in regular physical activity compared to those who did not. Preschool children who participated in regular physical activity had no neurological problems and exhibited better developmental parameters and physical fitness than their inactive peers.

En arrivant dans un pays dont on ne connaît ni la culture, ni la langue, les mots manquent pour communiquer. Comment alors exprimer ses besoins et ses ressentis, dans un contexte qui renforce précisément les opportunités d’expression de besoins et de ressentis ? En français, les mots savoir et saveur ont la même étymologie. Or, pour savoir une langue, le meilleur moyen n’est-il pas d’avoir justement accès à sa saveur ? Ce texte, à travers le compte rendu de diverses expériences artistiques avec des publics allophones, propose une réflexion sur l’importance de la sensibilité, du plaisir et du ludique pour aider à un apprentissage de la langue et des codes culturels du pays d’accueil, dont la nécessité exige a priori tout le contraire : rationalité, labeur et sérieux. Il développe enfin les nombreux et étonnants points de liaison entre la pratique pragmatique des artistes et intervenants avec leurs publics et la didactique structurée de l’enseignement des arts à l’école (notamment primaire) française.

Some panels and particleboards were made from reed mats and blends of reed-wood chips to be used inside buildings for sound and heat insulations. It was seen that the outer layers of the reed body (spike) was almost water resistant and exceptionally resistant to the penetration of common adhesives. Therefore, the panels from stitched reed mats exhibited very poor mechanical strength. The sound transmissions of such panels (1–3 km/s) made with various combinations, however, were recorded to be excellent compared with that of particleboards made of wood (17 km/s). Blends of reed chips (2 cm) and wood chips, however, gave particleboards with better mechanical properties (5–17 MPa) than that of panels made from reed mats (2 MPa). An increasing amount of reed chips in tested particleboards was recorded to be improving both sound and heat insulations from 17 to 6 km/s and from 0.34 to 0.27 W/mK, respectively. The bending strength of samples, however, was reduced from 26 to 5 MPa. Thickness swelling was also noted to increase from 18% to 85% due to reed chips addition. It was concluded that the outer layers of water reeds should be modified via chemical and/or enzymatic methods to increase the interfacial bounds between adhesives.

In this work, standard laboratory printing applications with IGT (ISO 12647-2) were applied on uncoated and matte-coated papers using offset inks (DIN ISO 2846-1). Surface roughnesses of uncoated and coated sheets were recorded to be 195 and 13 ml/min, respectively. Air permanence values of uncoated and coated papers were found to be 5.6 and 0.103 μm/Pa·s, respectively. Changes in the print densities were recorded up to 48 h. Print density changes for uncoated and matte-coated papers were surprisingly found to be in similar paths (8% in the first 4 h), although significant differences between surface roughnesses were recorded. Furthermore, paper samples showed similar behaviors for the percent volume changes, where drop volume disappeared within 6 min. It is concluded that matte coating did not have any significant effects on print density change and drop volume change.

A number of thin biomaterials were prepared via a wet formation method from seven different unbeaten plant fibers without using any chemical additives. It is noted that sheets made with short fibers (Flax-B: 0.32 mm and Straw-UB: 0.36 mm) and high fine content (Flax-B: 9.77% and Straw-UB: 10.64%) showed higher tensile index values (Flax-B: 27 Nm/g and Straw-UB: 25 Nm/g) than those made from long fibers. Despite having the longest fibers (1.11 mm) in studied samples, the tensile index values of sheet sample made from Pine-S-UB was just 12 Nm/g, which is just half of short-fibered (0.36 mm) straw sheets. Air permeability of sheets made from Pine-S-UB and Straw-UB were 5322 and 917 ml/min, respectively. Densities of the same sheets in the same order were 493 and 539 kg/m3. It is concluded that long cellulose fibers actually produce bulky materials with limited interfiber contacting areas, while short ones give biocomposites with higher density values indicating a firmly compacted internal structure in the case of utilizing plant fibers without beating and refining. Results would be usable when producing biocomposites from plant fibers via wet formation followed by various resins and polymer moldings.

Background: Formative assessments are needed to enable monitoring how student knowledge develops throughout a unit. Constructed response items which require learners to formulate their own free-text responses are well suited for testing their active knowledge. However, assessing such constructed responses in an automated fashion is a complex task and requires the application of natural language processing methodology. In this article, we implement and evaluate multiple machine learning models for coding energy knowledge in free-text responses of German K-12 students to items in formative science assessments which were conducted during synchronous online learning sessions. Dataset: The dataset we collected for this purpose consists of German constructed responses from 38 different items dealing with aspects of energy such as manifestation and transformation. The units and items were implemented with the help of project-based pedagogy and evidence-centered design, and the responses were coded for seven core ideas concerning the manifestation and transformation of energy. The data was collected from students in seventh, eighth and ninth grade. Methodology: We train various transformer- and feature-based models and compare their ability to recognize the respective ideas in students' writing. Moreover, as domain knowledge and its development can be formally modeled through knowledge networks, we evaluate how well the detection of the ideas within responses translated into accurate co-occurrence-based knowledge networks. Finally, in terms of the descriptive accuracy of our models, we inspect what features played a role for which prediction outcome and if the models pick up on undesired shortcuts. In addition to this, we analyze how much the models match human coders in what evidence within responses they consider important for their coding decisions. Results: A model based on a modified GBERT-large can achieve the overall most promising results, although descriptive accuracy varies much more than predictive accuracy for the different ideas assessed. For reasons of comparability, we also evaluate the same machine learning architecture using the SciEntsBank 3-Way benchmark with an English RoBERTa-large model, where it achieves state-of-the-art results in two out of three evaluation categories.

Clinical biochemistry laboratories (CBL) are the most frequently utilized laboratory group in healthcare, and their significance in patient care is indisputable. This study investigated the frequency and pattern of test utilization rate in CBL at two large hospitals’ outpatient and inpatient clinics.

Objective: The aim of this in vitro study was to investigate microorganism adhesion and biofilm formation between pure and ceramic-reinforced polyetheretherketone (PEEK) materials. Methods: A total of 72 rectangular (8 x 8 x 4 mm) samples were prepared from pure-PEEK without filler and PEEK (Ceramicreinforced PEEK - bio high-performance polymer) containing 20% nano-ceramic filler. A profilometer contact surface measurement device was used to assess the surface roughness of the samples. PEEK groups (36 pure PEEK, 36 Ceramic-reinforced PEEK) were divided into 4 sub-groups of 9 according to the microorganism strains. Staphylococcus aureus [American Type Culture Collection (ATCC 29213)], Acinetobacter baumannii (ATCC 19606), Enterococcus faecalis (ATCC 29212), and Candida albicans (ATCC 10231) standard strains were used for microbiological analysis. Blocks were added to 24-well microplates containing suspensions of microorganisms and were incubated at 37 °C for 72 hours. Microplates were read at a wavelength of 490 nm using crystal violet. Results: No significant difference was determined between the PEEK groups in terms of surface roughness. No significant differences in biofilm formation of S. aureus, A. baummanii, E. faecalis, and C. albicans strains were found between the PEEK groups (p>0.05). In the pure-PEEK, the highest adhesion was recorded in S. aureus (p

We are going through hard times that remind us that good health is the most important thing in life. The COVID-19 pandemic has immensely affected everybody. Measures taken by all countries, including Turkey, to prevent the spread of the coronavirus have deprived students (from preschool to university) of face-to-face education. While the pandemic has had a profound impact on parents and educators, children's lives have been stuck between the "new normal" and the pandemic. This paper investigated how children and their parents experienced the pandemic, how they interacted, and managed educational activities at home. This was a case study, which is a qualitative research method. The sample consisted of 15 families with different sociocultural and socioeconomic status (SES) living in five cities in four regions of Turkey. Data were collected through video-audio recordings, observation notes, and e-interviews. Data were analyzed using second-cycle coding and inductive content analysis. The COVID-19 pandemic caused economic problems, especially in lowand middle-SES families. Economic problems and mental stress impeded the marital interaction patterns of couples, negatively affecting children the most. Upper-SES parents received support from teachers for homeschooling, but other parents faced numerous setbacks and made numerous errors during home-based education, causing parents despair and concern for their children's future. Of all participants, the children of the parents with COVID-19 related health problems were affected by outbreak measures the most. These results can help raise all stakeholders' awareness of the current situation. Given that the COVID-19 pandemic may continue for the foreseeable future, it is believed that the suggestions made to parents and educators for homeschooling can help mitigate the future impacts of the pandemic, especially on preschoolers.

This study aimed to determine the views of thirty preservice preschool teachers recruited using convenience sampling on STEM education and engineering. Phenomenology was the design of choice. Data were collected using a semi-structured interview form and analyzed using inductive content analysis. Participants offered different definitions of STEM education and thought that it could have contributions in numerous aspects. They also remarked that preschool STEM education on civil and computer engineering skills made teachers better equipped. They mentioned designs and projects for preschool STEM education as well. However, they had the stereotypical image of engineering as a dirty job for men working in construction sites and carrying sand. Results suggest that preschool undergraduate education should integrate STEM activities and offer workshops and trainings to change preservice preschool teachers' misconceptions about engineering.

This paper investigated how puppetry could be used to improve the standards of early childhood science education. This study determined the effect of a puppet-making and puppetry workshop on preservice preschool teachers' beliefs and attitudes towards science education and looked into their experiences during and after puppet-making. Although participants faced some difficulties during the workshop, they developed numerous socioemotional skills. Puppetry activities can help preservice teachers learn how to deliver child-centered, stimulating, and interactive classes. Using puppets in early childhood science education can help teachers develop positive attitudes towards science and offer students high-quality, engaging, and creative activities.

Attitudes towards science and scientific perspectives in the future depend on early childhood science experiences. Preservice teachers who are provided with the opportunity to develop positive attitudes and self-efficacy towards science teaching before they enter professional life are more likely to help preschoolers develop positive attitudes towards science in their professional life. The aim of this 12-week study was, therefore, to determine the effect of a shadow play workshop on early childhood preservice teachers' self-efficacy beliefs and attitudes towards science teaching and to investigate their workshop experiences and application processes. This study employed an explanatory sequential mixed methods design. The sample consisted of 24 first-year early childhood preservice teachers. Quantitative data were collected using the Early Childhood Teachers' Attitudes Toward Science Teaching (TSAS) and the Science Teaching Efficacy Belief Instrument (STEBI) and were analyzed using the Wilcoxon Signed Ranks test and the dependent sample t-test. Qualitative data were collected through focus group interviews and observations and were analyzed using content analysis. Results showed that shadow play had a positive effect on participants' self-efficacy beliefs and attitudes towards science teaching, indicating that shadow play is an interesting, fun, and effective material that can be used in early childhood science education to turn abstract concepts into concrete forms. Results were discussed with reference to literature, and recommendations were made for future studies.

A Sportsmanship is a concept defined as the awareness of having the values required by sports and the golden key of sports activities. Family attitude and gender are thought to be among the concepts that affect sportsmanship. In this study, it was aimed to examine sportsmanship behavior with family attitude and gender characteristics. The research group consisted of 300 students randomly selected from the secondary schools in the city center of Antalya in the 2018-2019 education year, with a mean age of 12.48 ± 79. In the research conducted with the screening model, the "Physical Education Course Sportsmanship Behavior Scale (BEDSDÖ)" developed by Koç (2013) and a personal information form were used as data collection tools. In the analysis of the data, frequency, percentage, arithmetic mean and standard deviation were used as descriptive statistics methods for personal information. As the data showed normal distribution, the t-test for paired groups and the Anova test for multiple comparisons was used. According to the findings, it was determined that the sportsmanship behaviors of the students were at a high level. A statistically significant difference was found in favor of female students in the sub-dimensions of displaying appropriate behavior according to gender and avoiding inappropriate behavior and in the total of the scale. While there was no statistically significant difference in the dimension of exhibiting appropriate behavior according to the family attitudes of the students, the scores of the students who showed democratic family attitude were higher than the scores of the children of the families with free attitudes in the dimension of avoiding inappropriate behavior and in the total of the scale. When the sportsmanship behavior scores of secondary school students were examined, it was observed that the scores of the female students were higher than the male students. It is thought that changing family attitudes will improve the sportsmanship behaviors of the society.

This study was conducted to reveal the educational beliefs of prospective physical education and sports teachers, who receive education at the higher education level in Turkey, according to dependent and independent variables. Within this scope, the "Educational Belief Scale" was used to collect the data from 359 prospective teachers. The data collected from the sample were first analyzed by SPSS 22.0 package software. In the correlation analysis, it was observed that the "Educational Beliefs Scale" and the progressivism subscale were correlated very strongly and positively, which was the strongest correlation in the analysis (r = 0.918; p < 0.05). In the regression analysis, four different model structures were created, where it was determined that the subscale with the highest prediction power for the "Educational Beliefs Scale" was the progressivism subscale that predicted 84% of the variance of the "Educational Beliefs Scale" (R[superscript 2] = 0.840). In conclusion, it was discovered that the prospective teachers did not internalize the fundamentalism, which is included in the traditional educational philosophy. Significant responsibilities fall on the shoulders of academics and decision-makers to enable prospective teachers to save the valuable sections of basic information and values of the past and transfer them to new generations while approaching teaching with a perspective that promotes the potential of new generations in building a better civilization upon the achievements of past generations.

Although NMBAs (Neuro Muscular Blocking Agents) have been used for a long time, postoperative residual curarization is still a significant problem. Nowadays, an agent named Sugammadex is used for the reversal of curarization. It has been presented as a safer agent than its predecessor, neostigmine. The main purpose of this study is to investigate the effects of Sugammadex on rat thoracic aorta and enlighten the mechanism of action and potential benefits in surgical operations with general anesthesia. Twenty Wistar albino rats were used for the experiments. Thoracic aorta segments have been removed and mounted to the organ bath. Contraction and relaxation responses were presented as a percentage of phenylephrine (3x10-5 M) contraction. After recording contractile responses of Sugammadex (10-8-10-4 M), relaxation responses of Sugammadex (10-8-10-4 M) have been recorded both in the presence and absence of L-NAME (3x10-5 M) (Potent Nitric Oxide Sentase Inhibitor). Finally, relaxation responses of sugammadex-rocuronium have been recorded. Sugammadex caused slightly noticeable and concentration-dependent contraction on isolated thoracic aorta strips. Sugammadex also caused potent and concentration-dependent relaxation on isolated rat thoracic aorta. The relaxation response caused by Sugammadex has been diminished significantly in the presence of L-NAME. Administration of rocuronium with Sugammadex did cause neither relaxation nor any additional contractile effect on isolated rat thoracic aorta strips. Sugammadex is a promising agent in reversing rocuronium-induced neuromuscular block. Although the adverse effects of this agent are not studied in detail, it seems Sugammadex is safer than neostigmine. The side effects of anesthetic agents are one of the main problems of surgical procedures, including neurosurgery, gynecology, and obstetrics. Especially acute hypotension may be fatal in neurosurgery and gynecological operations. Sugammadex should be used carefully in adjusted and individualized doses to avoid hypotension-related adverse effects. [Med-Science 2023; 12(3.000): 629-34]

This study was carried out to determine the effect of SA (salicylic acid) application on the yield, yield components, and fibre quality characteristics of cotton at different growth stages (squaring, flowering and squaring + flowering). The experiment was carried out at Siirt University, Faculty of Agriculture, Department of Field Crop’s experimental area during the 2022 cotton growing season. The experimental design was a split-plot design with four replications. The main plot and sub-plots consisted of SA applications [Control (0.0 mM), squaring (1.0 mM), flowering (1.0 mM), squaring (0.5 mM) + flowering (0.5 mM)] and varieties (MAY 455, Stoneville 468, Fiona), respectively. SA application and variety interactions were significant in terms of the first boll opening days and the number of nodes. There were significant differences between varieties, except for the number of monopodial branches, number of bolls, chlorophyll content value, normalised difference vegetation index value, and micronaire and fibre strength. The MAY 455 cotton variety had the highest values in terms of seed cotton yield (2993.1 kg ha−1) plant height (62.14 cm), boll weight (6.51 g), seed cotton weight per boll (4.90 g), number of seeds per boll (29.46), number of nodes to first fruiting branch (8.65), fibre yield (1361.0 kg ha−1) and 100-seed weight (8.82 g), while the Fiona variety came to the fore in terms of number of days to first boll opening (118.0 d), number of sympodial branches (7.56), number of nodes per plant (17.79), ginning percentage (46.45%), fibre length (828.52 mm) and fibre reflectance (82.18 Rd). There was a slight increase in yield (223.8 kg ha−1) compared to the control. SA application may show different effects on each cotton variety, and the positive effect may increase by applying SA at different intervals.

In this study, the provinces in which enterprises operate heavily in the Turkish furniture industrywere subjected to an efficiency assessment using the data envelopment analysis (DEA) method based on work accidentsand occupational diseases. The data related to the furniture industry was obtained from the Social Security Institution (SSI) and the Ministry of Labor and Social Security (MoLSS). The number of operating businesses and the number of employees insured in each province were evaluated as inputs for the analysis. The total number of workplace physicians and other health personnel in each province, the number of workplace physician and occupational safety centers and A, B, and C-class occupational health and safety specialists were used as outputs. The number of employees who experienced work accidents and occupational diseases, deaths resulting from work accidents and occupational diseases, total temporary disability periods, the number of beneficiaries, and the number of those receiving permanent disability income in each province were evaluated as undesirable outputs. The data was analyzed using the DEA method by modeling the undesired outputs in 6 different ways, and the efficiency of each province was determined. It was seen that Model 6 gave the most ideal results in DEA efficiency assessments. Aydın, Çanakkale, Diyarbakır, Eskişehir, Malatya, Muğla, Trabzon and Zonguldak were determined as the most effective provinces in terms of occupational health and safety. The results were evaluated along with the literature, and recommendations were presented.

Coğrafî özellikleri bakımından nemli iklim bölgelerinde yetiştirilmeye uygun olan fındık bitkisi, Türkiye’de ilk defa Giresun’da üretilmeye başlanmış olup ülkenin dış ticaretinde tarımsal ihraç ürün olma özelliğiyle önem arz eden ürünler arasında yerini almıştır. Eskiçağlardan beri tanınıp bilinen ve tarihi süreç içinde özel bir yere sahip olan fındık, şimdilerde Kahramanmaraş´ın Kalekaya Mahallesi için ekonomik bir ürün haline gelmiştir. Çalışmada Kalekaya’daki fındık üretiminin yörede bilinirliğinin arttırılması ve farkındalık yaratılması, fındığın yöre ekonomisine ve istihdamına yönelik katkısının belirlenip üretim sürecinde karşılaşılan sorunların ortaya konması amaçlanmıştır. Çalışmada veri toplama aracı olarak yarı yapılandırılmış görüşme formu kullanılmış, fındık üreticileri ile yapılan görüşmeler tablolar haline getirilerek değerlendirilmiştir. Katılımcılar, fındık üretimini dedelerinden öğrendiklerini ve uzun yıllarda bir kültür haline gelen bu üretimden memnun olduklarını ifade etmişlerdir. Kırsal bir mekân olan Kalekaya ve çevresinde fındık üretiminde doğru gübre kullanımıyla verimliliğin arttırılabileceği ve fındığın yörede önemli bir istihdam alanı oluşturup çevre il ve ilçelere olan göçü azaltacağı düşünülmektedir.

Forcipomyia Meigen, 1818, is the second-largest genus of the family Ceratopogonidae, having medico veterinary and agricultural importance. A few mitogenomes of Ceratopogonidae have previously been available. Here, we aimed to characterize the whole mitogenome of Forcipomyia pulchrithorax Edwards, 1924, collected from Central Anatolia Region of the Türkiye using NGS to contribute to the genetic diversity within this family. The mitogenome of F. pulchrithorax (OR666457) consisted of a circular DNA molecule spanning 15,930 bp and containing 72.7% AT content. It includes 13 proteincoding genes (PCGs), 22 transfer RNA (tRNA) genes, 2 ribosomal RNA (rRNA) genes, and 1 control region. All PCGs exhibited typical ATN start codons and followed the conventional TAN stop codons, except COX1, COX2, COX3, ND1, and ND5, which ended with incomplete codons. The 22 tRNA genes demonstrated the ability to form a cloverleaf structure, except tRNA-Ser1, which lacked DHU arm, similar to most insect mitogenomes. The ML phylogenetic analyses clearly delineated the species of Culicomorpha into well supported monophyletic clades. Forcipomyia pulchrithorax was clustered with the Ceratopogonidae species constituting an outer taxon among the Culicomorpha. The comprehensive mitogenome of F. pulchrithorax will be valuable for future studies focused on the phylogenetic characterization and diversity of Ceratopogonidae within the Culicomorpha.

Abstract Acute myeloid leukemia (AML) is a heterogeneous disease and the most common form of acute leukemia with a poor prognosis. Due to its complexity, the disease requires the identification of biomarkers for reliable prognosis. To identify potential disease genes that regulate patient prognosis, we used differential co‐expression network analysis and transcriptomics data from relapsed, refractory, and previously untreated AML patients based on their response to treatment in the present study. In addition, we combined functional genomics and transcriptomics data to identify novel and therapeutically potential systems biomarkers for patients who do or do not respond to treatment. As a result, we constructed co‐expression networks for response and non‐response cases and identified a highly interconnected group of genes consisting of SECISBP2L, MAN1A2, PRPF31, VASP, and SNAPC1 in the response network and a group consisting of PHTF2, SLC11A2, PDLIM5, OTUB1, and KLRD1 in the non‐response network, both of which showed high prognostic performance with hazard ratios of 4.12 and 3.66, respectively. Remarkably, ETS1, GATA2, AR, YBX1, and FOXP3 were found to be important transcription factors in both networks. The prognostic indicators reported here could be considered as a resource for identifying tumorigenesis and chemoresistance to farnesyltransferase inhibitor. They could help identify important research directions for the development of new prognostic and therapeutic techniques for AML.

The "One Health" concept is a universal approach to sustainably balancing and optimizing the health of humans, animals, and ecosystems. This approach is based on the health of humans, domestic and wild animals, and plants in a wider environment in which self-renewable ecosystems exist, with essential characteristics of integration, unifying and holistic perspective. Toxoplasmosis, one of the most common zoonotic infections in both terrestrial and oceanic ecosystems in the world, is an ideal model disease for the “One Health” approach. Toxoplasmosis is a zoonotic disease caused by the obligate intracellular pathogen protozoan Toxoplasma gondii. In the life cycle of T. gondii, the definitive host is domestic cats and felines, and the intermediate hosts are all mammals (including humans), birds and reptiles. The infected cats have primary importance and play a crucial role in the contamination of habitats in the ecosystems with T. gondii oocysts. Thus, ecosystems with domestic cats and stray cats are contaminated with cat feces infected with T. gondii oocytes. T. gondii positivity has been scientifically demonstrated in all warm-blooded animals in terrestrial and aquatic habitats. The disease causes deaths and abortions in farm animals, resulting in great economic losses. However, the disease causes great problems in humans, especially pregnant women. During pregnancy, it may have effects such as congenital infections, lesions in the eye and brain of the fetus, premature birth, intrauterine growth retardation, fever, pneumonia, thrombocytopenia, ocular lesions, encephalitis, and abortion. The mechanism of death and abortion of the fetus in a pregnant woman infected with T. gondii occurs as a result of complete disruption of the maternal immune mechanism. The struggle against toxoplasmosis requires the universal collaboration and coordination of the World Organization for Animal Health, the World Health Organization and the World Food Organization in the "One Health" concept and integrative approaches of all responsible disciplines. Establishing universal environmental safety with the prevention and control of toxoplasmosis requires the annihilation of the feces of the infected cats using suitable techniques firstly. Then routinely, the monitoring and treatment of T. gondii positivity in cats, avoiding contact with contaminated foods and materials, and development of modern treatment and vaccine options. Particularly, mandatory monitoring or screening of T. gondii positivity during the pregnancy period in humans should be done. It would be beneficial to replace the French model, especially in the monitoring of disease in humans. In this article, the ecology of toxoplasmosis was reviewed at the base of the "One Health" concept.

This study aims to examine the relationships between value orientations and motivational action conflicts of adolescents and to determine how the value orientations predict motivational action conflicts and motivational action conflicts predicts value orientations. The research was carried out within the framework of the cross-sectional screening model. The research group consists of 833 (50.9% girls, 49.1% boys) students who are studying in different types of high schools (Science High School, Anatolian High School, High School, and Technical High School) in Kocaeli province. In research, the "Value Orientations Scale" and the "Motivational Action Conflict Scale" have been used as data collection tools. As a result of the research, there were significant relationships between value orientations and motivational action conflict. In conflict, which constitutes a conflict of motivational action, the decision was made as a result of learning, studying and leisure time meaningfully predicts achievement value orientations. It was also found that decision, learning, studying and leisure time in conflict significantly predicts well-being value orientations. It has been determined that achievement and well-being value orientations significantly predict decisions in conflict. Again, achievement and well-being value orientations are found to be a meaningful predictor of learning/studying. Besides, achievement and well-being have resulted in value orientations meaningfully predicting leisure time. Value orientations and motivational action conflicts in adolescents are proposed to be studied experimentally and with different variables as well.

The global COVID-19 outbreak has caused an anxious situation in every part of society and forced many countries to implement distance education programs without even knowing the fundamental components involved in the processes and the consequences of their decisions. Likewise, in Turkey, it is still uncertain as to what will be taught, what instructional technologies will be employed, how infrastructural inequalities will be addressed, and how assessment and evaluation activities will be conducted. In this context, the purpose of this study was (a) to examine the experiences and opinions of academics, Distance Education Center managers, students, and parents and (b) offer solutions to emerging issues. In doing so, a qualitative research approach was employed, and the study was designed as a phenomenology. The data were collected from 175 individuals from 20 universities through Google Forms. The second cycle coding methods were employed in the analysis. The results indicated that COVID-19 had mostly psychological effects on individuals, and it affected every level of education at varying degrees. The pandemic reminded us how hopelessly we are dependent on traditional means of instruction by rendering us unable to use them. Since the beginning of the outbreak, many higher education institutions have been trying to implement distance education; however, the quality of instruction is rather questionable. This situation threatens the quality of learning outcomes and if not approached with due diligence, results could be catastrophic. Also, this mandatory transition to distance education has made the difference between the experienced and inexperienced academics more apparent. In light of the results, recommendations were provided for national and international policymakers. As long as the recommendations were implemented, all higher education stakeholders could attain the required knowledge and skills, and, in return, the adverse effects of the COVID-19 pandemic could be alleviated.

This study attempts to explore for different profiles of information seeking behaviors on Facebook and to analyze whether or not personality, time management, gender and Facebook use are viable differentiating students based on the their profiles. The data were collected through self-report scales from 196 university students of the three public universities. Cluster analysis was used to explore the profiles. Discriminant analysis was performed to identify a boundary among the students' profiles based on personality, time management, gender and Facebook use of students. We found five different clusters based on information seeking behaviors of Facebook of the students. The results show significant differences among these clusters. The result of discriminant analysis indicates that personality, time management and Facebook use are meaningful for discriminating information seeking behavior groups of students. The study reveals that students with high scores of information seeking behavior on Facebook have also high scores on openness to experience, agreeableness, conscientiousness and extroversion, time management skills. In spite of its limitations, the study certainly adds to our understanding of profiles of students using Facebook as a source of information.

The study aims to investigate how the participation of secondary school students in sportive activities affects their life skills. For this purpose, the study included 708 voluntary students, 396 males, and 312 females, in the 2019-2020 education period. In the study, the Life Skills Scale for Sport (LSSS) was used as the data collection tool to evaluate the levels of life skills. To analyze the data collected in the study, SPSS 21 statistics package software was used. The data were analyzed for normality. As a result of the tests, because it was observed that the data did not have normality distribution, non-parametric tests were utilized. For two-sample comparisons, the Mann Whitney U test was used while the Kruskal Wallis H test was utilized for multiple-sample comparisons. In the study, the level of significance was regarded as p<0.05. The findings of the study indicated that there were significant differences in the life skill levels of the sample group according to the variables of age, gender, grade, the status of exercising and playing in school teams. In conclusion, it was concluded that the life skill levels of 14-year-old students (communication, time management, leadership, teamwork, emotional skills, and social skills) were high while sportive activities were more effective on female students at this age interval compared to male students. It was also observed that participating in school teams enabled positive gains on life skills.

This study focused on the effects of variables related to nomophobia levels of youths for adults; and exhibited a nomophobia profile of an adult by means of the significant variables about adults. Two hundred-ten adults from 30 different occupational groups participated in the research. The relational research design was used in the research. Data after collecting through scales were subjected to logistic regression analysis and two-step clustering analysis. As a result of the analysis, it was determined that while the nomophobia scores of the participated adults who were married, had children, were 30 years and older, have higher life satisfaction scores and lower social media addiction scores were low. On the other hand, it was determined that the adult in high nomophobia scores were clustered in the group who were single and did not have children, were between the ages of 24-29, had low life satisfaction scores and high social media addiction.

This study was designed to investigate the association between motivational action conflict frequency and value orientation as well as sociodemographic correlates of value orientation among Turkish high school students. Participants consisted of 846 students in different high schools from Marmara Region of Turkey and completed Motivational Action Conflict Frequency Survey and Value Orientation Scale. Results of this study suggested that students have average well-being value orientation and low achievement value orientation. There was no significant association between achievement and well-being value orientation and school-leisure time conflict; however, a weak and positive significant relationship exist between achievement value orientation and school time-school time conflict and leisure time-leisure time conflict, and there was a negative low-level significant relationship between well-being value orientation and school time-school time conflict and leisure time-leisure time conflict. The students' achievement and well-being value orientation were significantly different based on gender and daily studying times. Well-being value orientation associated with high school type, but no significant difference found in achievement value orientation. Lastly, there was no significant difference in value orientation in terms of grade level. The results of this study may also help to understand the correlates of value orientation and motivational conflict frequency in Turkish literature where a very limited number of studies have been conducted. [This study was presented as a verbal presentation at ERPA International Congresses on Education 2017.]

The book sets "Preschool Education Activity Guidebook" for teachers and "Let's Join Hands for Preschool Education" for children have been provided by the Ministry of National Education to all preschool education institutions since 2017 in order to provide high-quality preschool education, to help teachers develop different perspectives, and to discourage both students and teachers from using unreliable or inappropriate sources of information. The aim of this study was to determine the effects of the book sets on teachers and children. Phenomenology, which is qualitative research design, was used. The sample consisted of 24 preschool teachers from different educational institutions. Data were collected using interview forms created in Google Forms. Data were analyzed using second-cycle coding, which is inductive content analysis. Many participants are satisfied with the activity guidebooks and use them to develop different perspectives, to improve themselves, and to be more productive for their students. Teaching experiences and classroom materials affect the way they use the activity guidebooks. Although the book sets have some negative effects, they are guides for both teachers and parents. Participants think that the book sets are useful for education planning and process management but that different variables should also be taken into account when integrating them in education and that all available resources should be used to achieve professional development.