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195 results on '"Karadag, Bilgehan"'

8. Impact of preloading strategy with ticagrelor on periprocedural myocardial injury in patients with non-ST elevation myocardial infarction undergoing early invasive strategy

Author

Karaca, Orhan Furkan, primary, Cimci, Murat, additional, Raimoglou, Damla, additional, Durmaz, Eser, additional, Yalman, Hakan, additional, Tekin, Alpin Mert, additional, Incesu, Gunduz, additional, Ozkan, Ferit Ulas, additional, Yavuz, Betul, additional, and Karadag, Bilgehan, additional

Published
2024
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11. Safety and efficacy of coronary angiographic image integration tool-guided ablation of left sided outflow tract ventricular arrhythmias

Author

Yalin, Kivanc, primary, Soysal, Ali Ugur, additional, Aksu, Tolga, additional, Onder, Sukriye Ebru, additional, Ozturk, Sila, additional, Yalman, Hakan, additional, Mutlu, Deniz, additional, Ercan, Osman Talha, additional, Ikitimur, Baris, additional, Cimci, Murat, additional, Durmaz, Eser, additional, Karadag, Bilgehan, additional, Bilge, Ahmet Kaya, additional, Huang, Henry, additional, and Karpuz, Hakan, additional

Published
2023
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12. The Validation of Left Atrial Strain Imaging for the Assessment of Diastolic Functions in Patients with ST-Segment Elevation Myocardial Infarction

Author

Durmaz, Eser, primary, Karpuz, Mehmet Hakan, additional, Ikitimur, Baris, additional, Karadag, Bilgehan, additional, Koca, Damla, additional, Tokdil, Kardelen Ohtaroglu, additional, Raimoglu, Utku, additional, Gulfidan, Asli, additional, Incesu, Gunduz, additional, Tokdil, Hasan, additional, Pirdal, Betul Zehra, additional, and Ongen, Zeki, additional

Published
2022
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15. 2021 Asian Pacific Society of Cardiology Consensus Recommendations on the Use of P2Y12 Receptor Antagonists in the Asia-Pacific Region: Special Populations

Author

Tan, Jack Wei Chieh, primary, Chew, Derek P, additional, Tsui, Kin Lam, additional, Tan, Doreen, additional, Duplyakov, Dmitry, additional, Hammoudeh, Ayman, additional, Zhang, Bo, additional, Li, Yi, additional, Xu, Kai, additional, Ong, Paul J, additional, Firman, Doni, additional, Gamra, Habib, additional, Almahmeed, Wael, additional, Dalal, Jamshed, additional, Tam, Li-Wah, additional, Steg, Gabriel, additional, Nguyen, Quang N, additional, Ako, Junya, additional, Al Suwaidi, Jassim, additional, Chan, Mark, additional, Sobhy, Mohamed, additional, Shehab, Abdulla, additional, Buddhari, Wacin, additional, Wang, Zulu, additional, Fong, Alan Yean Yip, additional, Karadag, Bilgehan, additional, Kim, Byeong-Keuk, additional, Baber, Usman, additional, Chin, Chee Tang, additional, and Han, Ya Ling, additional

Published
2021
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21. Management of periprocedural anticoagulant therapy: a novel individualized approach—a transeusophageal echocardiographic study

Author

Durmaz, Eser, primary, Karadag, Bilgehan, additional, İkitimur, Baris, additional, Ebren, Cansu, additional, Tokdil, Hasan, additional, Koca, Damla, additional, Ozmen, Emre, additional, Polat, Fuat, additional, Ohtaroglu Tokdil, Kardelen, additional, Raimoglu, Utku, additional, Mutlu, Deniz, additional, Atici, Adem, additional, and Ongen, Zeki, additional

Published
2020
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25. Left atrial thrombus in patients with atrial fibrillation and under oral anticoagulant therapy; 3-D transesophageal echocardiographic study

Author

Baris Ikitimur, Damla Koca, Adem Atici, Eser Durmaz, Kardelen Ohtaroglu Tokdil, Emre Özmen, Karadag Bilgehan, Sedat Giray Kandemirli, Zeki Öngen, Mehmet Hakan Karpuz, Cansu Ebren, and Fuat Polat

Subjects
Male, medicine.medical_specialty, Echocardiography, Three-Dimensional, Administration, Oral, 030204 cardiovascular system & hematology, 03 medical and health sciences, 0302 clinical medicine, Predictive Value of Tests, Risk Factors, Internal medicine, Atrial Fibrillation, medicine, Humans, Radiology, Nuclear Medicine and imaging, In patient, Atrial Appendage, cardiovascular diseases, Prospective Studies, Thrombus, Left atrial thrombus, Stroke, Cardiac imaging, Aged, Aged, 80 and over, Ejection fraction, business.industry, Anticoagulants, Atrial fibrillation, Thrombosis, Middle Aged, medicine.disease, Treatment Outcome, Oral anticoagulant, Cardiology, Female, Cardiology and Cardiovascular Medicine, business, 030217 neurology & neurosurgery, Echocardiography, Transesophageal
Abstract

Ischemic stroke is the major complication of atrial fibrillation (AF) and only proven preventive therapy is oral anticoagulant therapy (OAC). Previous studies reported the presence of thrombus in the left atrium (LA) or left atrial appendage (LAA) despite anticoagulant therapy. We aim to investigate the predictors of LA/LAA thrombus in patients under OAC therapy and long-term clinical impact of thrombus. We prospectively enrolled consecutive patients with permanent AF under OAC therapy. Patients baseline characteristics were recorded. Transesophageal echocardiographic study performed after complete transthoracic echocardiographic study. 3-D evaluation of LAA was made using 3-D zoom mode and thrombus was defined when echo reflecting, mobile mass detected. Patients clinical outcomes were decided according to hospital records or via phone calls. Among 184 patients, 28 LAT were detected. Mean CHA2DS2-VASc score was significantly higher in patients with LAT in comparison to patients without LAT. CHA2DS2-VASc score (p: 0.001), left atrial volume (p: 0.001), left atrial flow velocity (p: 0.006) and left ventricular ejection fraction (p: 0.014) were independently associated with LAT. Among the parameters in CHA2DS2-VASc score, the previous history of stroke and age were independently related to LAT. After 12 months of follow-up, patients with LAT had more ischemic stroke than patients without LAT (7.1% vs 4.4%, p: 0.001 respectively). Although oral anticoagulation is the default treatment strategy for prevention of LAT and thromboembolism in patients with non-valvular AF, LAT still can be detected especially in patients with a high CHA2DS2-VASc score. Furthermore, the presence of LAT is significantly associated with future ischemic stroke.

Published
2019

28. The clinical significance of premature atrial contractions: How frequent should they become predictive of new‐onset atrial fibrillation

Author

Durmaz, Eser, primary, Ikitimur, Baris, additional, Kilickiran Avci, Burcak, additional, Atıcı, Adem, additional, Yurtseven, Ece, additional, Tokdil, Hasan, additional, Ebren, Cansu, additional, Polat, Fuat, additional, Karaca, Orhan, additional, Karadag, Bilgehan, additional, and Ongen, Zeki, additional

Published
2019
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29. The clinical significance of premature atrial contractions: How frequent should they become predictive of new-onset atrial fibrillation.

Author

Durmaz, Eser, Ikitimur, Baris, Kilickiran Avci, Burcak, Atıcı, Adem, Yurtseven, Ece, Tokdil, Hasan, Ebren, Cansu, Polat, Fuat, Karaca, Orhan, Karadag, Bilgehan, and Ongen, Zeki

Subjects
ATRIAL fibrillation diagnosis, AMBULATORY electrocardiography, ATRIAL arrhythmias, ATRIAL fibrillation, RETROSPECTIVE studies, RISK assessment, LONGITUDINAL method, DISEASE complications
Abstract

Background: Although previous studies reported frequent premature atrial contractions(fPACs) increased the risk of adverse cardiovascular outcomes, especially atrial fibrillation(AF), there is a substantial inconsistency between reports concerning the definition of fPAC. In this study, we aimed to investigate the relationship between fPAC and cardiovascular outcomes, especially AF. We further searched for a cutoff value of fPAC for prediction of AF.Methods: We retrospectively analyzed the ambulatory 24-hr Holter monitoring records and 392 patients included. Frequent PAC was defined as more than 720 PAC/24 hr as used for frequent ventricular premature beats. Patients' baseline characteristics, echocardiographic variables and medical history were recorded.Results: There were 189 patients with fPAC and 203 patients without fPAC. Patients with fPAC had more comorbidities in terms of hypertension, diabetes mellitus, coronary artery disease and congestive heart failure. CHA2DS2-VaSc was higher in patients with fPAC. Mean follow-up duration was 31 months, and the number of patients with new-onset AF during follow-up was significantly higher in fPAC group (22% vs. 5%, p < .001). fPAC was significantly and independently associated with new-onset AF and predicted AF with a cutoff value of 3,459 PAC/24 hr, and the risk of AF was 11-fold higher than those with <3,000 PAC/24 hr. In addition, an increased CHA2DS2-VaSc score was also associated with new-onset atrial fibrillation.Conclusion: In our study, we have demonstrated that fPAC is significantly associated with new-onset AF, and this association is the strongest among those patients who have more than 3,000 PAC in 24 hr. [ABSTRACT FROM AUTHOR]

Published
2020
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30. Cardiac arrest in a soccer player: a unique case of anomalous coronary origin detected by 16-row multislice computed tomography coronary angiography

Author

Karadag, Bilgehan, Spieker, Lukas E., Wildermuth, Simon, Boehm, Thomas, Corti, Roberto, Karadag, Bilgehan, Spieker, Lukas E., Wildermuth, Simon, Boehm, Thomas, and Corti, Roberto

Abstract

Anomalous origin of the coronary arteries may be present in otherwise normal subjects without clinical significance, but can also be the cause of myocardial ischemia and sudden death in both adults and teenagers. In particular, the origin of the left main coronary artery or left anterior descending artery from the right sinus of Valsalva or right coronary artery may result in compression of the vessel during or immediately after exercise. We present a unique case of coronary anomaly with four separate coronary ostia originating from the right coronary sinus in a soccer player with sudden cardiac arrest. Multislice contrast-enhanced computed tomography has emerged as a valid noninvasive method for the diagnosis of coronary artery anomaly

Published
2018

31. Rapid progression of atherosclerotic coronary artery disease in patients with human immunodeficiency virus infection

Author

Spieker, Lukas E., Karadag, Bilgehan, Binggeli, Christian, Corti, Roberto, Spieker, Lukas E., Karadag, Bilgehan, Binggeli, Christian, and Corti, Roberto

Abstract

We describe the case of a 39-year-old human immunodeficiency virus (HIV)-infected man with angiographically documented rapid progression of coronary artery disease. Over a time course of only 2 months, he developed high-grade stenosis of the left anterior descending coronary artery. The risk of myocardial infarction is increased in patients with HIV infection receiving antiretroviral therapy. However, the absolute risk is small and the marked overall benefits of antiretroviral therapy are evident. Patients receiving HIV protease inhibitors should be screened for hyperlipidemia, hyperglycemia, and hypertension. They may be candidates for lipid-lowering therapies depending on their long-term prognosis and individual risk of cardiovascular disease. Care is need because of possible drug interactions between lipid-lowering drugs and antiretroviral therapy. Invasive treatment of acute myocardial infarction does not differ from that in patients not infected with HIV. The rate of progression of coronary artery disease and the restenosis rate, however, are often unexpectedly high in these patients

Published
2018

42. Effects of levosimendan versus dobutamine on left atrial function in decompensated heart failure

Author

Fatih Palit, Dursun Duman, Atalay Sacide, Karadag Bilgehan, and Ergun Simsek

Subjects
Adult, Male, medicine.medical_specialty, Cardiotonic Agents, medicine.drug_class, Doppler imaging, Electrocardiography, Young Adult, Internal medicine, Dobutamine, Clinical Studies, medicine, Natriuretic peptide, Humans, Single-Blind Method, Prospective Studies, Infusions, Intravenous, Simendan, Aged, Aged, 80 and over, Heart Failure, Ejection fraction, medicine.diagnostic_test, Dose-Response Relationship, Drug, business.industry, Hydrazones, Levosimendan, Middle Aged, medicine.disease, Pyridazines, medicine.anatomical_structure, Treatment Outcome, Ventricle, Echocardiography, Anesthesia, Heart failure, Cardiology, Atrial Function, Left, Female, Cardiology and Cardiovascular Medicine, business, medicine.drug, Follow-Up Studies
Abstract

Background Although the effects of levosimendan on the left ventricle (LV) have been studied, its effect on left atrial (LA) function is poorly understood, despite its key role in optimizing LV function. Objective To compare the effects of levosimendan and dobutamine on LA and LV function in patients with decompensated heart failure (DHF). Methods Seventy-four patients (mean [± SD] age 64±10 years) with DHF and an LV ejection fraction of 35% or lower were randomly assigned to receive levosimendan (n=37) or dobutamine (n=37). LA active emptying fraction, LA passive emptying fraction (PEF) and the ratio of mitral inflow early diastolic velocity to annulus velocity (E/e) were evaluated with pulsed wave and tissue Doppler imaging along with plasma B-type natriuretic peptide (BNP) level measurements before and after drug infusion. Results The ejection fraction was significantly increased in both groups. The levosimendan group had a greater decrease in BNP and a greater increase in active emptying fraction at 24 h compared with the dobutamine group. The PEF, E/e and deceleration time of the E wave were significantly improved in the levosimendan group, but not in the dobutamine group. Levosimendan- induced percentage change of BNP was significantly correlated with the percentage change of E/e and PEF (r=0.48 [P Conclusions In patients with DHF, levosimendan and dobutamine both improve LV systolic function. However, levosimendan also improves LV diastolic function and LA performance in parallel with a greater improvement in neurohormonal activation compared with dobutamine.

Published
2009

43. Serum carbohydrate antigen 125 levels in advanced heart failure: relation to B-type natriuretic peptide and left atrial volume

Author

Karadag Bilgehan, Dursun Duman, Fatih Palit, and Ergun Simsek

Subjects
Male, medicine.medical_specialty, medicine.drug_class, Cardiac Volume, Severity of Illness Index, Cohort Studies, Predictive Value of Tests, Internal medicine, Severity of illness, Natriuretic Peptide, Brain, medicine, Natriuretic peptide, Humans, cardiovascular diseases, Heart Atria, Aged, Body surface area, Heart Failure, Ejection fraction, business.industry, Stroke Volume, Stroke volume, Middle Aged, medicine.disease, Predictive value of tests, Heart failure, CA-125 Antigen, cardiovascular system, Cardiology, Linear Models, Female, Cardiology and Cardiovascular Medicine, business
Abstract

Aims To assess the relation between serum levels of carbohydrate antigen 125 (CA 125) and parameters of left ventricular (LV) filling pressure in patients with advanced heart failure (AHF). Methods Forty-nine patients (mean age 67±10 years) with LV ejection fraction (EF) ≤0.35 and New York Heart Association (NYHA) class III or IV symptoms of heart failure were enrolled. Left atrial volume indexed to body surface area (LAVI) and the ratio of mitral inflow early diastolic velocity to annulus velocity (E/e) were evaluated with pulsed wave and tissue Doppler. Plasma B-type natriuretic peptide (BNP) was also measured. Results The median overall CA 125 value was 44.0 (17.7–140) U/ml. CA 125 above the normal value (

Published
2008

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