Search

Background/Aims: This study was conducted to determine the development of post-traumatic stress disorder (PTSD) in children, who had spent time in an intensive care unit, as well as in their parents. Methods: The study was a cross-sectional study. 110 children, 98 mothers and 80 fathers were included in the study. Results: The average PTSD score was 34.46±15.89 in children, 53.66±16.93 in mothers, and 33.24±14.61 in fathers. A positive relationship was found between the PTSD scores of the children, mothers and fathers (p<0.05). Conclusion: The study found that PTSD could develop in children and their parents after the children had been hospitalized in intensive care. Amaç: Çalışma, yoğun bakım ünitesinde yatmış 8-12 yaş arası çocuklar ve ebeveynlerinde TSSB (Travma Sonrası Stres Bozukluğu) gelişimini belirlemek amacıyla yapıldı. Yöntem: Kesitsel tipte bir çalışmadır. Çalışmaya 110 çocuk, 98 anne ve 80 baba dahil edildi. Bulgular: Çocuklarda TSSB puanı ortalaması 34,46±15,89, annelerde 53,66±16,93, babalarda 33,24±14,61 olarak bulundu. Çocuk, anne ve babanın TSSB puanları arasında pozitif yönde ilişki saptandı (p<0,05). Sonuç: Çalışma sonucunda yoğun bakımda yatan çocuklarda ve ebeveynlerinde TSSB gelişebildiği görüldü. [ABSTRACT FROM AUTHOR]

Oxidative damage caused by aflatoxin (AF) in rat liver tissue and the inhibition effect of lycopene against this injury was investigated. Groups were formed as; control group (not treated), lycopene group (5 mg/kg/day, gavage for 15 days), AFB1 group (0.5 mg/kg/day, gavage for 7 days) and AFB1 + lycopene group. Lycopene administered simultaneously with AFB1. It was observed significant increase in malondialdehyde level, decrease in glutathione level, antioxidant enzyme activities in liver tissue of AFB1 group when compared with control group. It was determined to significantly increase in plasma aspartate transaminase, alanine transaminase, lactate dehydrogenase activities in AFB1 group when compared with control group. It was determined significant decrease in malondialdehyde level, plasma aspartate transaminase, alanine transaminase, lactate dehydrogenase activities and increase in glutathione level, antioxidant enzyme activities in AFB1 + lycopene group when compared with AFB1 group. This study suggests that lycopene which has antioxidant properties can be prevented from AFB1 induced hepatotoxicity. [ABSTRACT FROM AUTHOR]