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191 results on '"Kantelhardt, Eva J."'

10. Treatment guideline concordance, initiation, and abandonment in patients with non-metastatic breast cancer from the African Breast Cancer–Disparities in Outcomes (ABC-DO) cohort in sub-Saharan Africa: a prospective cohort study

Author

Foerster, Milena, McCormack, Valerie, Anderson, Benjamin O, Boucheron, Pauline, Zietsman, Annelle, Cubasch, Herbert, Joffe, Maureen, Anele, Angelica, Offiah, Shadrach, Galukande, Moses, Parham, Groesbeck, Pinder, Leeya F, Ginsburg, Ophira, Schüz, Joachim, dos-Santos-Silva, Isabel, and Kantelhardt, Eva J

Published
2022
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12. A Qualitative Study on Psychosocial Challenges of Patients With Cancer in Ethiopia Using the Social-Ecological Model.

Author

Wondimagegnehu, Abigiya, Assefa, Mathewos, Teferra, Solomon, Kantelhardt, Eva J., Zebrack, Bradley, and Addissie, Adamu

Subjects
MIDDLE-income countries, FEAR, CONCEPTUAL models, QUALITATIVE research, PSYCHOLOGICAL distress, SUICIDAL ideation, ATTITUDES toward illness, RESEARCH funding, RURAL hospitals, QUESTIONNAIRES, DESCRIPTIVE statistics, ANXIETY, PSYCHOLOGY, THEMATIC analysis, CONCEPTUAL structures, URBAN hospitals, SOCIAL skills, ATTITUDES of medical personnel, TUMORS, CANCER patient psychology, RESOURCE-limited settings, SOCIAL support, NEEDS assessment, COMPARATIVE studies, DATA analysis software, LOW-income countries, RELIGIOUS leaders, MENTAL depression, PATIENTS' attitudes
Abstract

Cancer diagnosis and treatment can be physically arduous, disrupting patients' social and work lives. Understanding the extent of these problems is key to addressing patients' needs, but specific psychosocial challenges have not yet been well studied in resource-limited settings. A qualitative study was conducted in the capital and two regions of Ethiopia with the aim of exploring psychosocial challenges among cancer patients. A total of 14 in-depth interviews (IDIs) and 16 focus group discussions (FGDs) were done with cancer patients, health professionals, community representatives, and religious leaders. Four separate interview guides were used to facilitate the interviews and discussions. All transcribed documents, field notes, and reflexive memos were entered into NVivo 12 software, and deductive thematic analysis using the social-ecological model was applied to summarize the main findings. At an individual level, emotional distress, suicidal risk, denial, and refusal of treatment were identified immediately after diagnosis while hopelessness, feeling depressed, and fear of death were commonly reported psychosocial challenges during the course of treatment. Involvement of family members in major treatment decisions was recognized at an interpersonal level. Our result also revealed that cancer patients had strong social support from family members and close friends. In the community, traditional medicine and religious rituals were considered an alternative treatment for cancer. The findings indicate that counselling and psychoeducation are crucial for cancer patients, family members, and close friends. Awareness creation programmes should be delivered through collaboration with religious leaders and traditional healers. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Ovarialzyste

Author

Kantelhardt, Eva J., Papendick, Nancy, Wacker, Jürgen, editor, Sillem, Martin, editor, Bastert, Gunther, editor, and Beckmann, Matthias W., editor

Published
2020
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16. Immunohistochemistry-derived subtypes of breast cancer distribution in four regions of Ethiopia

Author

Belachew, Esmael Besufikad, primary, Desta, Adey Feleke, additional, Gebremariam, Tewodros Yalew, additional, Deneke, Dinikisira Bekele, additional, Ashenafi, Senait, additional, Yeshi, Melisachew Mulatu, additional, Fenta, Bizunesh Dires, additional, Alem, Alemwosen T/Hayimanot, additional, Alemu, Addisu, additional, Abafogi, Abdo Kedir, additional, Desta, Tigist, additional, Chanyalew, Menberework, additional, Beshah, Daniel, additional, Taylor, Lesley, additional, Bauer, Marcus, additional, Tsehay, Dareskedar, additional, Girma, Selfu, additional, Melka, Daniel Seifu, additional, Tessema, Tesfaye Sisay, additional, Kantelhardt, Eva J., additional, and Howe, Rawleigh, additional

Published
2023
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17. Catastrophic Health Expenditure and Associated Factors Among Hospitalized Cancer Patients in Addis Ababa, Ethiopia.

Author

Matebie, Girum Yihun, Mebratie, Anagaw Derseh, Demeke, Tamiru, Afework, Bezawit, Kantelhardt, Eva J, and Addissie, Adamu

Subjects
HOSPITAL patients, CANCER patients, HEALTH insurance, MEDICAL care costs, ECONOMIC impact, CANCER hospitals
Abstract

Background: Out-of-pocket (OOP) health expenditures for cancer care expose households to unanticipated economic consequences. When the available health services are mainly dependent on OOP expenditure, the household faces catastrophic health expenditure (CHE). This study aimed to estimate the incidence and intensity of CHE in hospitalized cancer patients and identify coping strategies and associated factors. Method and Material: Hospital-based cross-sectional study design was conducted on 305 cancer inpatients in Addis Ababa between November 2021 and February 2022. All patients with cancer who were hospitalized during the data collection period were included in the study. The incidence of CHE was estimated at the 40% threshold of households' non-food expenditure and the intensity of CHE was captured based on the amount by which household expenditure exceeded the threshold and mean positive overshoot, the mean level by which CHE exceeds the threshold used. Multivariate logistic regression was used to assess the relationship between CHE levels and the independent variables. Results: The incidence of CHE at the 40% threshold of households' non-food expenditure was 77.7%, while the O and MPO were 36.2% and 46.6%, respectively. CHE for cancer care was significantly associated with patient residence, increased number of chemotherapy cycles, increased duration of hospital admission, lack of insurance enrolment, and lower-income quintiles. Saving and selling assets were identified as the primary coping mechanisms. Conclusion: The incidence and intensity of CHE among inpatients with cancer were high and which could lead to impoverishment of households. Improved quality and coverage of health insurance and decentralizing cancer care to regions standards similar to Addis Ababa will save households from incurring CHE. [ABSTRACT FROM AUTHOR]

Published
2024
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20. Treatment and Survival Among Patients With Colorectal Cancer in Sub-Saharan Africa: A Multicentric Population-Based Follow-Up Study

Author

Hämmerl, Lucia, primary, Mezger, Nikolaus C.S., additional, Seraphin, Tobias P., additional, Joko-Fru, Walburga Yvonne, additional, Griesel, Mirko, additional, Feuchtner, Jana, additional, Gnahatin, Franck, additional, Gnangnon, Freddy Houéhanou Rodrigue, additional, Okerosi, Nathan, additional, Amulen, Phoebe Mary, additional, Hansen, Rolf, additional, Borok, Margaret Ziona, additional, Carrilho, Carla, additional, Mallé, Brahima, additional, Ahoui Apendi, Clausina, additional, Buziba, Nathan G., additional, Seife, Edom, additional, Liu, Biying, additional, Mikolajczyk, Rafael, additional, Parkin, Donald M., additional, Kantelhardt, Eva J., additional, and Jemal, Ahmedin, additional

Published
2023
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22. Supplementary Figure 4 from Regional Variation in the Tumor Microenvironment, Immune Escape and Prognostic Factors in Breast Cancer in Sub-Saharan Africa

Author

Bauer, Marcus, primary, Vetter, Martina, primary, Stückrath, Kathrin, primary, Yohannes, Meron, primary, Desalegn, Zelalem, primary, Yalew, Tewodros, primary, Bekuretsion, Yonas, primary, Kenea, Tariku W., primary, Joffe, Maureen, primary, van den Berg, Eunice J., primary, Nikulu, Julien I., primary, Bakarou, Kamate, primary, Manraj, Shyam S., primary, Ogunbiyi, Olufemi J., primary, Ekanem, Ima-Obong, primary, Igbinoba, Festus, primary, Diomande, Mohenou, primary, Adebamowo, Clement, primary, Dzamalala, Charles P., primary, Anele, Angelica A., primary, Zietsman, Annelle, primary, Galukande, Moses, primary, Foerster, Milena, primary, dos-Santos-Silva, Isabel, primary, Liu, Biying, primary, Santos, Pablo, primary, Jemal, Ahmedin, primary, Abebe, Tamrat, primary, Wickenhauser, Claudia, primary, Seliger, Barbara, primary, McCormack, Valerie, primary, and Kantelhardt, Eva J., primary

Published
2023
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23. Clinicopathological Features of Invasive Breast Cancer: A Five-Year Retrospective Study in Southern and South-Western Ethiopia

Author

Belachew, Esmael Besufikad, primary, Desta, Adey Feleke, additional, Deneke, Dinksira Bekele, additional, Fenta, Bizunesh Dires, additional, Alem, Alemwosen Teklehaymanot, additional, Abafogi, Abdo Kedir, additional, Lukas, Fekade Yerakly, additional, Bezabih, Mesele, additional, Sewasew, Dareskedar Tsehay, additional, Kantelhardt, Eva J., additional, Tessema, Tesfaye Sisay, additional, and Howe, Rawleigh, additional

Published
2023
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24. Regional variation in the tumor microenvironment, immune escape and prognostic factors in breast cancer in sub-Saharan Africa

Author

Bauer, Marcus, primary, Vetter, Martina, additional, Stückrath, Kathrin, additional, Yohannes, Meron, additional, Desalegn, Zelalem, additional, Yalew, Tewodros, additional, Bekuretsion, Yonas, additional, Kenea, Tariku W., additional, Joffe, Maureen, additional, Van Den Berg, Eunice J., additional, Nikulu, Julien Ilunga., additional, Bakarou, Kamaté, additional, Manraj, Shyam S., additional, Ogunbiyi, Olufemi J., additional, Ekanem, Ima-Obong, additional, Igbinoba, Festus, additional, Diomande, Mohenou, additional, Adebamowo, Clement, additional, Dzamalala, Charles P., additional, Anele, Angelica A., additional, Zietsman, Annelle, additional, Galukande, Moses, additional, Foerster, Milena, additional, dos-Santos-Silva, Isabel, additional, Liu, Biying, additional, Santos, Pablo, additional, Jemal, Ahmedin, additional, Abebe, Tamrat, additional, Wickenhauser, Claudia, additional, Seliger, Barbara, additional, McCormack, Valerie, additional, and Kantelhardt, Eva J., additional

Published
2023
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27. Adjuvant Docetaxel in Node-Negative Breast Cancer Patients: A Randomized Trial of AGO-Breast Study Group, German Breast Group, and EORTC-Pathobiology Group

Author

Thomssen, Christoph, primary, Vetter, Martina, additional, Kantelhardt, Eva J., additional, Meisner, Christoph, additional, Schmidt, Marcus, additional, Martin, Pierre M., additional, Clatot, Florian, additional, Augustin, Doris, additional, Hanf, Volker, additional, Paepke, Daniela, additional, Meinerz, Wolfgang, additional, Hoffmann, Gerald, additional, Wiest, Wolfgang, additional, Sweep, Fred C. G. J., additional, Schmitt, Manfred, additional, Jänicke, Fritz, additional, Loibl, Sibylle, additional, Minckwitz, Gunter von, additional, and Harbeck, Nadia, additional

Published
2023
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28. Abstract P1-11-11: HER2-directed therapy in early breast cancer – improvement over 20 years

Author

Thomssen, Christoph, primary, Engel, Julia, additional, Reinhardt, Kristin, additional, Strauß, Hans-Georg, additional, Große, Regina, additional, Barrot, Susanne, additional, Bauer, Marcus, additional, van Uden, Lisa, additional, Kaufhold, Sandy, additional, Schüler, Kathleen, additional, Wieder, Vanessa, additional, Kantelhardt, Eva J., additional, and Vetter, Martina, additional

Published
2023
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30. Ovarialzyste

Author

Kantelhardt, Eva J., Göpel, Christian, Wacker, Jürgen, editor, Sillem, Martin, editor, Bastert, Gunther, editor, and Beckmann, Matthias W., editor

Published
2013
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31. Klimawandel und Klimafolgenanpassung als Lernziel in der medizinischen Ausbildung – ein Beispiel

Author

Ludwig, Christiane, Mezger, Nikolaus Christian Simon, Feller, Stephan, Jahn, Patrick, Meyer, Gabriele, Kantelhardt, Eva J., and Walldorf, Jens

Subjects
Medicine and health
Abstract

Lernziel: Die Vermittlung von Wissen zu den Folgen des Klimawandels und Implikationen für Klimaschutz und Klimafolgenanpassung ist nicht nur für Studierende der Medizin relevant, sondern betrifft alle Akteure im Gesundheitswesen. Möglichkeiten der curricular verankerten Ausbildung zu [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022
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35. Curative Treatment for Non-Metastatic Breast Cancer in Sub-Saharan Africa: Guideline Concordance, Initiation, and Abandonment in the Prospective ABC-DO Cohort

Author

Foerster, Milena, McCormack, Valerie, Anderson, Benjamin O., Boucheron, Pauline, Zietsman, Annelle, Cubasch, Herbert, Joffe, Maureen, Anele, Angelica, Offiah, Shadrach, Galukande, Moses, Parham, Groesbeck, Pinder, Leeya F., Ginsburg, Ophira, Schüz, Joachim, dos-Santos-Silva, Isabel, and Kantelhardt, Eva J.

Subjects
Adult, Male, History, Adolescent, Polymers and Plastics, Breast Neoplasms, Article, Industrial and Manufacturing Engineering, Cohort Studies, South Africa, Outcome Assessment, Health Care, Humans, Female, Prospective Studies, Business and International Management
Abstract

Comprehensive breast cancer management is essential to achieve high breast cancer survival; however, detailed reports of the treatment regimens received by patients are scarce in sub-Saharan Africa where survival is low. We aimed to examine treatment initiation, guideline concordance, and abandonment in patients with non-metastatic breast cancer in sub-Saharan Africa from the African Breast Cancer-Disparities in Outcomes (ABC-DO) prospective cohort.The ABC-DO prospective cohort study recruited women (aged ≥18 years) with newly diagnosed invasive breast cancer in eight hospitals across five sub-Saharan African countries (Namibia, Nigeria, Uganda, South Africa, and Zambia). We analysed treatments received by women who were classified as non-metastatic (M0) at the initial presentation. Data on surgery, radiotherapy, and systemic therapies were obtained from medical records and a self-reported follow-up questionnaire at 6 months after the diagnosis, follow-up calls every 3 months, and a baseline questionnaire. Initiation, completion, and abandonment of treatment modalities and combined therapy regimens were examined overall, by country-specific groups, and by clinical factors relevant for guideline-based treatment.Of 2313 women recruited into the ABC-DO study between Sept 10, 2014, and Dec 31, 2017, 2226 had histologically or clinically confirmed breast cancer. Of these 2226 women, 510 were excluded from the present analysis because 378 had metastatic disease, 37 were prevalent cases (defined as those previously diagnosed with breast cancer2 years before baseline), 82 had unknown TNM stage, and 13 were White or Asian women in South Africa (number was too small for analysis). After a median follow-up of 5·2 years (IQR 4·6-5·9), 1163 (68%) of 1716 women underwent breast cancer surgery. Surgery and systemic therapy (ie, multimodality treatment) with radiotherapy was initiated in 370 (36%) of 1028 women with localised tumours versus 156 (23%) of 688 women with locally advanced tumours, whereas multimodality treatment without radiotherapy was initiated in 386 (38%) versus 167 (24%) women, respectively. Of 1530 patients requiring chemotherapy (which excludes 105 who died within 6 months after baseline), 1013 (66%) initiated treatment of neoadjuvant chemotherapy or surgery within 3 months after baseline, which was adequately completed by 359 (35%) of 1013 women, marginally completed by 284 (28%), abandoned by 200 (20%), and unknown in 151 (15%). 19 (2%) women died within 6 months after chemotherapy initiation. Of 1375 women in whom endocrine therapy was indicated, this treatment was initiated in 920, and lasted at least 3 years in 367 (40%) women. Treatment disparities between country-specific groups were substantial for all therapy regimens.A high proportion of patients with non-metastatic breast cancer did not initiate, did not fully complete, or abandoned treatment with surgery, systemic therapy, radiotherapy, or an appropriate combination of these, highlighting the need for improved treatment access and completion in sub-Saharan Africa to potentially prevent premature breast cancer deaths.National Institutes of Health (National Cancer Institute), Susan G Komen, and the International Agency for Research on Cancer.

Published
2022

36. Additional file 1 of Breast cancer morbidity and mortality in rural Ethiopia: data from 788 verbal autopsies

Author

Ayele, Wondimu, F��hrer, Amand, Braun, Gabriele Anna, Formazin, Franziska, Wienke, Andreas, Taylor, Lesley, Unverzagt, Susanne, Addissie, Adamu, and Kantelhardt, Eva J.

Abstract

Additional file 1. Age structure used on the study���s population compared to those of documented deaths at Kersa Health and Demographic surveillance site of Ethiopia.

Published
2022
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40. Cervical Cancer in Sub-Saharan Africa: A Multinational Population-Based Cohort Study of Care and Guideline Adherence

Author

Griesel, Mirko, primary, Seraphin, Tobias P., additional, Mezger, Nikolaus C.S., additional, Hämmerl, Lucia, additional, Feuchtner, Jana, additional, Joko-Fru, Walburga Yvonne, additional, Sengayi-Muchengeti, Mazvita, additional, Liu, Biying, additional, Vuma, Samukeliso, additional, Korir, Anne, additional, Chesumbai, Gladys C., additional, Nambooze, Sarah, additional, Lorenzoni, Cesaltina F., additional, Akele-Akpo, Marie-Thérèse, additional, Ayemou, Amalado, additional, Traoré, Cheick B., additional, Wondemagegnehu, Tigeneh, additional, Wienke, Andreas, additional, Thomssen, Christoph, additional, Parkin, Donald M., additional, Jemal, Ahmedin, additional, and Kantelhardt, Eva J., additional

Published
2021
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41. Rising Prostate Cancer Incidence in Sub-Saharan Africa: A Trend Analysis of Data from the African Cancer Registry Network

Author

Seraphin, Tobias P., primary, Joko-Fru, Walburga Y., additional, Kamaté, Bakarou, additional, Chokunonga, Eric, additional, Wabinga, Henry, additional, Somdyala, Nontuthuzelo I.M., additional, Manraj, Shyam S., additional, Ogunbiyi, Olufemi J., additional, Dzamalala, Charles P., additional, Finesse, Anne, additional, Korir, Anne, additional, N'Da, Guy, additional, Lorenzoni, Cesaltina, additional, Liu, Biying, additional, Kantelhardt, Eva J., additional, and Parkin, Donald M., additional

Published
2021
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43. Abstract A118: Optimization of end point PCR for the determination of ESR1, PGR, and ERBB2 expression level in resource-limited settings: Ethiopian context

Author

Woldesonbet, Zelalem Desalegn, primary, Vetter, Martina, additional, Nigussie, Meron Yohannes, additional, Zeleke, Tamrat Abebe, additional, Bekuretsion, Yonas, additional, Arayselassie, Mahlet, additional, Assefa, Mathewos, additional, Bekele, Abebe, additional, Anberber, Endale, additional, Wickenhauser, Claudia, additional, Kantelhardt, Eva J, additional, Bukur, Jürgen, additional, and Barbara, Seliger, additional

Published
2020
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44. Abstract B020: Antiproliferative efficacy of different targeted drugs on breast cancer cell lines of distinct subtypes

Author

Nigussie, Meron Yohannes, primary, Bukur, Jürgen, additional, Woldesonbet, Zelalem Desalegn, additional, Zeleke, Tamrat Abebe, additional, Bekuretsion, Yonas, additional, Arayselassie, Mahlet, additional, Assefa, Mathewos, additional, Bekele, Abebe, additional, Anberber, Endale, additional, Vetter, Martina, additional, Wickenhauser, Claudia, additional, Kantelhardt, Eva J, additional, and Seliger, Barbara, additional

Published
2020
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46. Abstract C031: NanoString nCounter-based gene expression assay for evaluation of breast cancer molecular subtypes in Ethiopian patients

Author

Woldesonbet, Zelalem Desalegn, primary, Vetter, Martina, additional, Nigussie, Meron Yohannes, additional, Zeleke, Tamrat Abebe, additional, Bekuretsion, Yonas, additional, Arayselassie, Mahlet, additional, Assefa, Mathewos, additional, Bekele, Abebe, additional, Anberber, Endale, additional, Wickenhauser, Claudia, additional, Kantelhardt, Eva J., additional, Bukur, Jürgen, additional, and Seliger, Barbara, additional

Published
2020
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47. Clinical presentation and diagnosis of adult patients with non‐Hodgkin lymphoma in Sub‐Saharan Africa

Author

Mezger, Nikolaus C. S., primary, Feuchtner, Jana, additional, Griesel, Mirko, additional, Hämmerl, Lucia, additional, Seraphin, Tobias P., additional, Zietsman, Annelle, additional, Péko, Jean‐Félix, additional, Tadesse, Fisihatsion, additional, Buziba, Nathan G., additional, Wabinga, Henry, additional, Nyanchama, Mary, additional, Borok, Margaret Z., additional, Kéita, Mamadou, additional, N'da, Guy, additional, Lorenzoni, Cesaltina F., additional, Akele‐Akpo, Marie‐Thérèse, additional, Gottschick, Cornelia, additional, Binder, Mascha, additional, Mezger, Jörg, additional, Jemal, Ahmedin, additional, Parkin, Donald M., additional, Wickenhauser, Claudia, additional, and Kantelhardt, Eva J., additional

Published
2020
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49. Oesophageal Cancer Magnitude and Presentation in Ethiopia

Author

Wondimagegnehu, Abigiya, primary, Hirpa, Selamawit, additional, Abaya, Samson Wakuma, additional, Gizaw, Muluken, additional, Getachew, Sefonias, additional, Ayele, Wondimu, additional, Yirgu, Robel, additional, Demeke, Tamiru, additional, Dessalegn, Berhe, additional, Diribi, Jilcha, additional, Kaba, Mirgissa, additional, Assefa, Mathewos, additional, Jemal, Ahmedin, additional, Kantelhardt, Eva J., additional, and Addissie, Adamu, additional

Published
2019
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