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415 results on '"Kang, H.J."'

8. Crystal structure of human GPCR Niacin receptor (HCA2)

Author

Yang, Y., primary, Kang, H.J., additional, Gao, R.G., additional, Wang, J.J., additional, Han, G.W., additional, FiBerto, J.F., additional, Wu, L.J., additional, Tong, J.H., additional, Qu, L., additional, Wu, Y.R., additional, Pileski, R., additional, Li, X.M., additional, Zhang, X.C., additional, Zhao, S.W., additional, Kenakin, T., additional, Wang, Q., additional, Stevens, R.C., additional, Peng, W., additional, Roth, B.L., additional, Rao, Z.H., additional, and Liu, Z.J., additional

Published
2023
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10. Effects of genomic estimated breeding value and dietary energy to protein ratio on growth performance, carcass trait, and lipogenic gene expression in Hanwoo steer

Author

Park, S.J., primary, Kim, H., additional, Piao, M., additional, Kang, H.J., additional, Fassah, D.M., additional, Jung, D.J.S., additional, Kim, S.Y., additional, Na, S.W., additional, Beak, S.-H., additional, Jeong, I.H., additional, Yoo, S.P., additional, Hong, S.J., additional, Lee, D.H., additional, Lee, S.H., additional, Haque, M.N., additional, Shin, D.-J., additional, Kwon, J.A., additional, Jo, C., additional, and Baik, M., additional

Published
2023
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14. Cryo-EM Structure of Human Niacin Receptor HCA2-Gi protein complex

Author

Yang, Y., primary, Kang, H.J., additional, Gao, R.G., additional, Wang, J.J., additional, Han, G.W., additional, DiBerto, J.F., additional, Wu, L.J., additional, Tong, J.H., additional, Qu, L., additional, Wu, Y.R., additional, Pileski, R., additional, Li, X.M., additional, Zhang, X.C., additional, Zhao, S.W., additional, Kenakin, T., additional, Wang, Q., additional, Stevens, R.C., additional, Peng, W., additional, Roth, B.L., additional, Rao, Z.H., additional, and Liu, Z.J., additional

Published
2023
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19. 206MO Treatment patterns in patients with mantle cell lymphoma: Report of the Asia-Pacific multinational retrospective registry study

Author

Cho, H., primary, Yoon, D.H., additional, Kim, D.J., additional, Kang, K-W., additional, Kwak, J-Y., additional, Tan, S-M., additional, Lee, J-O., additional, Oh, S.Y., additional, Do, Y.R., additional, Jeong, S.H., additional, Kang, H.J., additional, Koh, Y., additional, Kim, H.J., additional, Kim, S-H., additional, Won, J.H., additional, Chen, T-Y., additional, Yang, D.H., additional, Chin, N.S., additional, Eom, H-S., additional, and Kim, W.S., additional

Published
2022
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20. Reproductive Factors and Subtypes of Breast Cancer Defined by Estrogen Receptor, Progesterone Receptor, and Human Epidermal Growth Factor Receptor 2: A Register-Based Study From Korea

Author

Ahn, S.H., Bae, J.W., Bae, Y.T., Baek, J.W., Bong, J.G., Cha, K.H., Chang, E.S., Chang, I.T., Chang, S.S., Cho, J.W., Cho, S.H., Cho, Y.U., Choi, J.W., Choi, K.J., Choi, M.S., Choi, S.I., Choi, S.Y., Goo, G.S., Han, S.H., Han, W., Hong, S.J., Hwang, J.Y., Hyun, T.I., Jegal, Y.J., Im, M.G., Joh, Y.G., Jun, S.Y., Jung, B.W., Jung, J., Jung, J.H., Jung, K.H., Jung, P.J., Jung, S.H., Jung, S.S., Jung, Y.H., Jung, Y.S., Kang, D.H., Kang, H.J., Kang, Y.I., Kang, Y.J., Keum, J.H., Kim, D.Y., Kim, H.J., Kim, J.G., Kim, J.H., Kim, J.S., Kim, K.C., Kim, S.C., Kim, S.H., Kim, S.I., Kim, S.J., Kim, S.W., Kim, S.Y., Kim, Y.S., Ko, B.K., Ko, S.S., Koh, S.H., Koo, B.H., Koo, J.Y., Kwak, B.S., Lee, C.H., Lee, D.H., Lee, D.S., Lee, E.S., Lee, G.S., Lee, H.D., Lee, H.S., Lee, J.C., Lee, J.H., Lee, J.K., Lee, J.S., Lee, J.Y., Lee, K.M., Lee, K.P., Lee, K.S., Lee, K.Y., Lee, M.H., Lee, R.A., Lee, S.C., Lee, S.J., Lee, S.K., Lee, W., Lee, Y.H., Leu, J.W., Lim, C.H., Lim, C.W., Moon, B.I., Nam, Y.S., Nam, S.J., Noh, D.Y., Noh, W.C., Oh, S.J., Oh, S.S., Pae, W.K., Paik, I.W., Paik, N.S., Park, B.G., Park, B.W., Park, C.H., Park, H.B., Park, H.Y., Park, J.H., Park, K.H., Park, S.J., Park, S.T., Park, S.W., Park, W.C., Park, Y.K., Seo, H.S., Seo, K.H., Seo, Y.J., Sin, Y.S., Son, B.H., Son, G.S., Song, B .J., Song, K.H., Song, Y.J., Suh, Y.J., Won, J.M., Woo, D.H., Yang, D.H., Yang, J.H., Yoo, K.Y., Yoo, S.Y., Yoon, H.S., Yoon, J.H., Yoon, S.O., Lee, Jung Sun, and Oh, Minkyung

Published
2014
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30. The magnetized steel and scintillator calorimeters of the MINOS experiment

Author

Michael, D.G., Adamson, P., Alexopoulos, T., Allison, W.W.M., Alner, G.J., Anderson, K., Andreopoulos, C., Andrews, M., Andrews, R., Arroyo, C., Avvakumov, S., Ayres, D.S., Baller, B., Barish, B., Barker, M.A., Barnes, P.D., Jr., Barr, G., Barrett, W.L., Beall, E., Bechtol, K., Becker, B.R., Belias, A., Bergfeld, T., Bernstein, R.H., Bhattacharya, D., Bishai, M., Blake, A., Bocean, V., Bock, B., Bock, G.J., Boehm, J., Boehnlein, D.J., Bogert, D., Border, P.M., Bower, C., Boyd, S., Buckley-Geer, E., Byon-Wagner, A., Cabrera, A., Chapman, J.D., Chase, T.R., Chernichenko, S.K., Childress, S., Choudhary, B.C., Cobb, J.H., Coleman, S.J., Cossairt, J.D., Courant, H., Crane, D.A., Culling, A.J., Damiani, D., Dawson, J.W., de Jong, J.K., DeMuth, D.M., De Santo, A., Dierckxsens, M., Diwan, M.V., Dorman, M., Drake, G., Ducar, R., Durkin, T., Erwin, A.R., Escobar, C.O., Evans, J.J., Fackler, O.D., Falk Harris, E., Feldman, G.J., Felt, N., Fields, T.H., Ford, R., Frohne, M.V., Gallagher, H.R., Gebhard, M., Godley, A., Gogos, J., Goodman, M.C., Gornushkin, Yu., Gouffon, P., Grashorn, E.W., Grossman, N., Grudzinski, J.J., Grzelak, K., Guarino, V., Habig, A., Halsall, R., Hanson, J., Harris, D., Harris, P.G., Hartnell, J., Hartouni, E.P., Hatcher, R., Heller, K., Hill, N., Ho, Y., Howcroft, C., Hylen, J., Ignatenko, M., Indurthy, D., Irwin, G.M., James, C., Jenner, L., Jensen, D., Joffe-Minor, T., Kafka, T., Kang, H.J., Kasahara, S.M.S., Kilmer, J., Kim, H., Kim, M.S., Koizumi, G., Kopp, S., Kordosky, M., Koskinen, D.J., Kostin, M., Kotelnikov, S.K., Krakauer, D.A., Kumaratunga, S., Ladran, A.S., Lang, K., Laughton, C., Lebedev, A., Lee, R., Lee, W.Y., Libkind, M.A., Liu, J., Litchfield, P.J., Litchfield, R.P., Longley, N.P., Lucas, P., Luebke, W., Madani, S., Maher, E., Makeev, V., Mann, W.A., Marchionni, A., Marino, A.D., Marshak, M.L., Marshall, J.S., McDonald, J., McGowan, A.M., Meier, J.R., Merzon, G.I., Messier, M.D., Milburn, R.H., Miller, J.L., Miller, W.H., Mishra, S.R., Miyagawa, P.S., Moore, C.D., Morfín, J., Morse, R., Mualem, L., Mufson, S., Murgia, S., Murtagh, M.J., Musser, J., Naples, D., Nelson, C., Nelson, J.K., Newman, H.B., Nezrick, F., Nichol, R.J., Nicholls, T.C., Ochoa-Ricoux, J.P., Oliver, J., Oliver, W.P., Onuchin, V.A., Osiecki, T., Ospanov, R., Paley, J., Paolone, V., Para, A., Patzak, T., Pavlović, Ž., Pearce, G.F., Pearson, N., Peck, C.W., Perry, C., Peterson, E.A., Petyt, D.A., Ping, H., Piteira, R., Pla-Dalmau, A., Plunkett, R.K., Price, L.E., Proga, M., Pushka, D.R., Rahman, D., Rameika, R.A., Raufer, T.M., Read, A.L., Rebel, B., Reyna, D.E., Rosenfeld, C., Rubin, H.A., Ruddick, K., Ryabov, V.A., Saakyan, R., Sanchez, M.C., Saoulidou, N., Schneps, J., Schoessow, P.V., Schreiner, P., Schwienhorst, R., Semenov, V.K., Seun, S.-M., Shanahan, P., Shield, P.D., Shivane, R., Smart, W., Smirnitsky, V., Smith, C., Smith, P.N., Sousa, A., Speakman, B., Stamoulis, P., Stefanik, A., Sullivan, P., Swan, J.M., Symes, P.A., Tagg, N., Talaga, R.L., Terekhov, A., Tetteh-Lartey, E., Thomas, J., Thompson, J., Thomson, M.A., Thron, J.L., Trendler, R., Trevor, J., Trostin, I., Tsarev, V.A., Tzanakos, G., Urheim, J., Vahle, P., Vakili, M., Vaziri, K., Velissaris, C., Verebryusov, V., Viren, B., Wai, L., Ward, C.P., Ward, D.R., Watabe, M., Weber, A., Webb, R.C., Wehmann, A., West, N., White, C., White, R.F., Wojcicki, S.G., Wright, D.M., Wu, Q.K., Yan, W.G., Yang, T., Yumiceva, F.X., Yun, J.C., Zheng, H., Zois, M., and Zwaska, R.

Published
2008
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32. Effect of electron beam irradiation and storage on the quality attributes of sausages with different fat contents

Author

Kwon, J.H., Nam, K.C., Lee, E.J., Kang, H.J., and Ahn, D.U.

Subjects
Sausages -- Production processes, Sausages -- Quality management, Sausages -- Composition, Electron beam curing -- Research, Food -- Storage, Food -- Nutritional aspects, Zoology and wildlife conservation
Abstract

Sausages with different fat contents (16 or 29%) were purchased from local stores, vacuum-packaged in oxygen-impermeable bags, and irradiated at 0 or 5 kGy using a linear accelerator. The changes in quality attributes of irradiated sausages were determined during storage at 4[degrees]C. The 2-thiobarbituric acid-reactive substance values of sausages were not affected by fat content but were increased after irradiation (5 kGy). Storage for 60 d increased the 2-thiobarbituric acid-reactive substance values of nonirradiated sausages (P < 0.05) but had no effect on irradiated sausages. The numbers of volatile compounds and the amounts of total volatiles were increased by irradiation in both the high-fat (29% fat) and low-fat (16% fat) sausages. Dimethyl sulfide was detected only in irradiated sausages, regardless of fat content (P < 0.05), but it disappeared after 60 d of storage. Pentane and 1-heptene were detected only in irradiated samples after 60 d of storage. Low-fat sausages had greater [L.sup.*] values, but had lesser [a.sup.*] and [b.sup.*] values than high-fat sausages. Irradiation and storage had little effect on either the exterior or interior color ([L.sup.*], [a.sup.*], and [b.sup.*] values) of sausages. Fat content had no effect on the sensory variables of sausages, regardless of irradiation and storage. However, irradiated sausages had significantly stronger off-odors and off-flavors than nonirradiated sausages regardless of fat content (P < 0.05). This indicated that fat content in sausages had a minimal effect on the quality of irradiated sausages during storage. Key words: fat content, irradiation, quality, sausage doi: 10.2527/jas.2009-2382

Published
2010

34. Virtual discovery of melatonin receptor ligands to modulate circadian rhythms

Author

Kang, H.J., Cherezov, V., Savych, O., Kenakin, T., Shoichet, B.K., Glatfelter, G.C., Huang, X.-P., Roth, B.L., Johansson, L.C., Stauch, B., Slocum, S., Dubocovich, M.L., Moroz, Y.S., Che, T., Irwin, J.J., Stein, R.M., McCorvy, J.D., and Jones, A.J.

Abstract

The neuromodulator melatonin synchronizes circadian rhythms and related physiological functions through the actions of two G-protein-coupled receptors: MT1 and MT2. Circadian release of melatonin at night from the pineal gland activates melatonin receptors in the suprachiasmatic nucleus of the hypothalamus, synchronizing the physiology and behaviour of animals to the light–dark cycle1–4. The two receptors are established drug targets for aligning circadian phase to this cycle in disorders of sleep5,6 and depression1–4,7–9. Despite their importance, few in vivo active MT1-selective ligands have been reported2,8,10–12, hampering both the understanding of circadian biology and the development of targeted therapeutics. Here we docked more than 150 million virtual molecules to an MT1 crystal structure, prioritizing structural fit and chemical novelty. Of these compounds, 38 high-ranking molecules were synthesized and tested, revealing ligands with potencies ranging from 470 picomolar to 6 micromolar. Structure-based optimization led to two selective MT1 inverse agonists—which were topologically unrelated to previously explored chemotypes—that acted as inverse agonists in a mouse model of circadian re-entrainment. Notably, we found that these MT1-selective inverse agonists advanced the phase of the mouse circadian clock by 1.3–1.5 h when given at subjective dusk, an agonist-like effect that was eliminated in MT1- but not in MT2-knockout mice. This study illustrates the opportunities for modulating melatonin receptor biology through MT1-selective ligands and for the discovery of previously undescribed, in vivo active chemotypes from structure-based screens of diverse, ultralarge libraries. © 2020, The Author(s), under exclusive licence to Springer Nature Limited.

Published
2020
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37. Field-dependent ordered phases and Kondo phenomena in the filled skutterudite compound [PrOs.sub.4][As.sub.12]

Author

Maple, M.B., Butch, N.P., Frederick, N.A., Ho, P.C., Jeffries, J.R., Sayles, T.A., Yanagisawa, T., Yuhasz, W.M., Songxue, Chi, Kang, H.J., Lynn, J.W., Dai, Pengcheng, McCall, S.K., McElfresh, M.W., Fluss, M.J., Henkie, Z., and Pietraszko, A.

Subjects
Antiferromagnetism -- Analysis, Fermions -- Research, Kondo effect -- Usage, Kondo effect -- Analysis, Science and technology
Abstract

Electrical resistivity, specific heat, and magnetization measurements to temperatures as low as 80 mK and magnetic fields up to 16 T were made on the filled skutterudite compound [PrOs.sub.4][As.sub.12]. The measurements reveal the presence of two ordered phases at temperatures below approximately 2.3 K and in fields below approximately 3 T. Neutron-scattering experiments in zero field establish an antiferromagnetic ground state heavy fermion | Kondo effect | antiferromagnetism

Published
2006

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