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25 results on '"Kang, Chantal"'

1. Deep phenotyping and biomarkers of various dairy fat intakes in an 8-week randomized clinical trial and 2-year swine study

Author

Martin, Jean-Charles, Bal-dit-Sollier, Claire, Bard, Jean-Marie, Lairon, Denis, Bonneau, Michel, Kang, Chantal, Cazaubiel, Murielle, Marmonier, Corinne, Leruyet, Pascale, Boyer, Constance, Nazih, Hassan, Tardivel, Catherine, Defoort, Catherine, Pradeau, Marion, Bousahba, Imene, Hammou, Habib, Svilar, Ljubica, and Drouet, Ludovic

Published
2023
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3. Treatment of Renal Artery Aneurysm With the Multilayer Stent

Author

Henry, Michel, Polydorou, Antonios, Frid, Noureddine, Gruffaz, Patricia, Cavet, Alain, Henry, Isabelle, Hugel, Michèle, Rüfenacht, Daniel A., Augsburger, Luca, De Beule, Matthieu, Verdonck, Pascal, Bonneau, Maurice, Kang, Chantal, Ouared, Rafik, and Chopard, Bastien

Published
2008

4. A novel experimental thrombotic myocardial infarction and primary angioplasty model in swine

Author

Sideris, Georgios, primary, Magkoutis, Nikolaos, additional, Voicu, Sebastian, additional, Kang, Chantal, additional, Bonneau, Michel, additional, Yannopoulos, Demetris, additional, Bal Dit Sollier, Claire, additional, Dillinger, Jean-Guillaume, additional, Berge, Natacha, additional, Brouland, Jean-Philippe, additional, Henry, Patrick, additional, and Drouet, Ludovic, additional

Published
2019
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5. Synchronized Pulsatile Flow With Low Systolic Output From Veno-Arterial Extracorporeal Membrane Oxygenation Improves Myocardial Recovery After Experimental Cardiac Arrest in Pigs

Author

Voicu, Sébastian, Sideris, Georgios, Dillinger, Jean-Guillaume, Yannopoulos, Demetris, Deye, Nicolas, Kang, Chantal, Bonneau, Michel, Bartos, Jason, Kedra, Antoni, Bailliart, Sophie, Pasteur-Rousseau, Adrien, Amah, Guy, Bonnin, Philippe, Callebert, Jacques, Henry, Patrick, Mégarbane, Bruno, Hôpital Lariboisière-Fernand-Widal [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Division of Cardiology, Department of Medicine, Beth Israel Deaconess Medical Center [Boston] (BIDMC), Harvard Medical School [Boston] (HMS)-Harvard Medical School [Boston] (HMS), Centre de Recherche en Imagerie Interventionnelle Radiologie, Partenaires INRAE, and École de biologie industrielle (EBI)

Subjects
Left ventricular ejection fraction, Swine, [SDV]Life Sciences [q-bio], Heart Ventricles, Hemodynamics, Heart, Cardiac arrest, Heart Arrest, Extracorporeal Membrane Oxygenation, Pulsatile Flow, Synchronized pulsatile flow, Animals, Female, Pulmonary capillary pressure
Abstract

International audience; Circulatory failure following cardiac arrest (CA) requires catecholamine support and occasionally veno-arterial extracorporeal membrane oxygenation (vaECMO). VaECMO-generated blood flow is continuous and retrograde, increasing ventricular stroke work. Our aim was to assess the benefit of a device generating a pulsatile vaECMO flow synchronized with the heart rhythm lowering systolic vaECMO output on the left ventricular ejection fraction (LVEF) and pulmonary capillary pressure (Pcap) after CA. This experimental randomized study in pigs compared standard nonpulsatile vaECMO (control) with pulsatile synchronized vaECMO (study) group using a pulsatility-generating device. After sedation and intubation, ventricular fibrillation was induced by pacing. After 10-min ventricular fibrillation, cardiopulmonary resuscitation was performed for 20 min then vaECMO, defibrillation and 0.15 mu g/kg/min intravenous epinephrine infusion were initiated. Hemodynamics, Pcap, LVEF by echocardiography and angiography were measured at baseline and every 30 min after the vaECMO start until vaECMO and epinephrine were stopped (at 120 min), and 30 min later. Baseline hemodynamics did not differ between groups; 120 min after vaECMO initiation, LVEF by echocardiography and angiography was significantly higher in the study than control group 55 +/- 19% versus 34 +/- 13% (P=0.042), 50 +/- 16% versus 33 +/- 12% (P=0.043), respectively. Pcap decreased from baseline by 4.2 +/- 8.6 mm Hg in the study group but increased by 5.6 +/- 5.9 mm Hg in the control group (P=0.043). Thirty minutes later, LVEF remained higher in the study group 44 +/- 7% versus 26 +/- 11% (P=0.008) while Pcap did not differ. A synchronized pulsatile device decreasing systolic output from vaECMO improved LVEF and Pcap in a pig model of CA and resuscitation.

Published
2017

6. Synchronized Pulsatile Flow With Low Systolic Output From Veno‐Arterial Extracorporeal Membrane Oxygenation Improves Myocardial Recovery After Experimental Cardiac Arrest in Pigs

Author

Voicu, Sebastian, primary, Sideris, Georgios, additional, Dillinger, Jean‐Guillaume, additional, Yannopoulos, Demetris, additional, Deye, Nicolas, additional, Kang, Chantal, additional, Bonneau, Michel, additional, Bartos, Jason, additional, Kedra, Antoni, additional, Bailliart, Sophie, additional, Pasteur‐Rousseau, Adrien, additional, Amah, Guy, additional, Bonnin, Philippe, additional, Callebert, Jacques, additional, Henry, Patrick, additional, and Megarbane, Bruno, additional

Published
2018
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10. ENDOCOM: Implantable wireless pressure sensor for the follow-up of abdominal aortic aneurysm stented

Author

Romain, Olivier, Mazeyrat, Johan, Garda, Patrick, Talleb, Hakeim, Lautru, David, Wong, Man-Faï, Wiart, Joe, Fouad Hanna, Victor, Lagrée, Pierre-Yves, Bonneau, Michel, Kang, Chantal, Fernández, Miguel Angel, Gerbeau, Jean-Frédéric, Deplano, Valérie, Legallais, Cécile, Leprince, Pascal, Systèmes Electroniques (SYEL), Laboratoire d'Informatique de Paris 6 (LIP6), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Laboratoire d'Electronique et Electromagnétisme (L2E), Université Pierre et Marie Curie - Paris 6 (UPMC), Orange Labs [Issy les Moulineaux], France Télécom, Institut Jean Le Rond d'Alembert (DALEMBERT), Université Pierre et Marie Curie - Paris 6 (UPMC)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherche en Imagerie Interventionnelle (CR2I), Institut National de la Recherche Agronomique (INRA), Numerical simulation of biological flows (REO), Laboratoire Jacques-Louis Lions (LJLL), Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Inria Paris-Rocquencourt, Institut National de Recherche en Informatique et en Automatique (Inria)-Institut National de Recherche en Informatique et en Automatique (Inria), Institut de Recherche sur les Phénomènes Hors Equilibre (IRPHE), Aix Marseille Université (AMU)-École Centrale de Marseille (ECM)-Centre National de la Recherche Scientifique (CNRS), Université de Technologie de Compiègne (UTC), Service de neuro-radiologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (APHP)-CHU Pitié-Salpêtrière [APHP], Institut Jean le Rond d'Alembert (DALEMBERT), Biomécanique et Bioingénierie (BMBI), Université de Technologie de Compiègne (UTC)-Centre National de la Recherche Scientifique (CNRS), CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Centre National de la Recherche Scientifique (CNRS)-Aix Marseille Université (AMU)-École Centrale de Marseille (ECM), Service de Neuroradiologie [CHU Pitié-Salpêtrière], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), and Centre National de la Recherche Scientifique (CNRS)-Université Pierre et Marie Curie - Paris 6 (UPMC)

Subjects
medicine.medical_specialty, medicine.medical_treatment, Biomedical Engineering, Biophysics, 030204 cardiovascular system & hematology, 030230 surgery, Network configuration, In vivo tests, RFID pressure sensor, 03 medical and health sciences, 0302 clinical medicine, medicine.artery, medicine, In vivo experiments, cardiovascular diseases, Thrombus, Endovascular treatment, AAA, Aorta, business.industry, Stent, medicine.disease, Pressure sensor, Abdominal aortic aneurysm, 3. Good health, Surgery, [SPI.ELEC]Engineering Sciences [physics]/Electromagnetism, Numerical modelling, cardiovascular system, Radiology, business
Abstract

International audience; An abdominal aortic aneurysm (AAA) is a dilatation of the aorta at the abdominal level, the rupture of which is a life threatening complication with an 80% mortality rate. Even though those devices keep improving, the failure rate of the endovascular treatment is due to persisting pressure into the excluded aneurysmal sac. Since 2005, several integrated sensors have been designed for the follow-up of the AAA treated by a stent. Solutions are based on the use of a single sensor. Thrombus in the excluded AAA can modify the field of pressure when leaks appeared and a network of sensors should be used. We present in this paper the ENDOCOM project that aims to design an implantable pressure sensor that can be used in a network configuration. To validate the new materials, we developed a framework composed of in vitro experiments and in vivo tests on large animal model. Numerical modeling has been investigated from the experimental data to determine the optimal position of sensor. Some results of those different parts are shown in this paper.

Published
2011

17. Surface analysis of an encapsulation membrane after its implantation in mini-pigs.

Author

UCL - FSA/MAPR - Département des sciences des matériaux et des procédés, Henry, Marie, Ulrichs, Karin, Moskalenko, Vasily, Bonneau, Michel, Kang, Chantal, Belcourt, Alain, Bertrand, Patrick, UCL - FSA/MAPR - Département des sciences des matériaux et des procédés, Henry, Marie, Ulrichs, Karin, Moskalenko, Vasily, Bonneau, Michel, Kang, Chantal, Belcourt, Alain, and Bertrand, Patrick

Abstract

The biocompatibility of membranes aiming at being a part of a bioartificial pancreas has been tested. For that purpose, we have studied a polycarbonate membrane surface after its implantation in mini-pigs. The membranes were made hydrophilic by an argon plasma surface treatment followed by a dipping in a hydrophilic polymer solution. Two polymers were tested: polyvinylpyrrolidone (PVP) and hydroxypropylmethylcellulose (HPMC). To test their biocompatibility, an encapsulation device for pig Langerhans islets, with external membranes treated as described above, was implanted in different mini-pigs. The pigs received no further treatment. The devices were explanted after in vivo exposure and the membranes were analysed by XPS (x-ray photoelectron spectroscopy) and ToF-SIMS (time-of-flight secondary ion mass spectrometry). After this time, the substrate with the PVP or HPMC treatment was still detected on the different samples. The surface treatment signal, however, was attenuated. This is explained by the detection of other components partly covering the surface. XPS and ToF-SIMS analyses revealed the presence of biological molecules on the two faces of the membrane: the outside face in contact with the biological environment and the inside face in contact with the device. ToF-SIMS images show the inhomogeneity of the biological molecules on the membrane surface. In conclusion, biological molecules adhered to the encapsulation membrane surface after implantation but the surface treatments remained unaltered.

Published
2007

18. Kinetics of endothelialization of the multilayer flow modulator and single-layer arterial stents.

Author

Sultan, Sherif, Kavanagh, Edel P., Bonneau, Michel, Kang, Chantal, Alves, Antoine, and Hynes, Niamh M.

Abstract

The multilayer flow modulator (MFM; Cardiatis, Isnes, Belgium) is a self-expandable mesh of braided cobalt alloy wires, used for treatment of aortic and peripheral aneurysms. To further improve our understanding of this novel technology, the endothelialization kinetics of the MFM was investigated and compared with those of two marketed single-layer stents. Five porcine animal models were used in which a total of 19 stents were implanted in the iliac and carotid arteries between one and five weeks before sacrifice. All 19 stents were successfully delivered. For all devices, nonsignificant signs of inflammation or thrombosis were noted, and there was no evidence of local intolerance. The MFM developed a thin layer of endothelial cells earlier and was associated with less neointimal development than the two single-layer stents. A differing phenomenon of integration was also revealed and hypothesized as endothelialization from adhesion of circulating endothelial progenitor cells, as well as adhesion from the arterial wall, and also by the differences in trauma exposed to the arterial wall. [ABSTRACT FROM AUTHOR]

Published
2016
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19. RFID implantable pressure sensor for the follow-up of abdominal aortic aneurysm stented

Author

Romain, Olivier, primary, Mazeyrat, Johan, additional, Garda, Patrick, additional, Talleb, H., additional, Lautru, D., additional, Wong, M. F., additional, Wiart, J., additional, Hanna, V. Fouad, additional, Lagree, Pierre Yves, additional, Bonneau, Michel, additional, Kang, Chantal, additional, Fernandez, Miguel, additional, Gerbeau, Jean-Frederic, additional, Deplano, Valerie, additional, Berthier, Bernard, additional, Legallais, Cecile, additional, and Leprince, Pascal, additional

Published
2011
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25. Study of fibrosis induced by an implanted medical device

Author

Laboratoire de l'Intégration du Matériau au Système (IMS) ; UMR CNRS 5218 - Université de Bordeaux 1 - ENSEIRB-MATMECA, Institut de Nanotechnologie de Lyon (INL) ; Université de Lyon 1, Laboratoire d'Informatique, de Robotique et de Microélectronique de Montpellier (LIRMM) ; UMR CNRS 5506 - Université de Monpellier 2, Institut de Biologie et Chimie des Protéines (IBCP) ; Université de Lyon 1, Lab-STICC_TB_CACS_IAS ; Département Electronique (ELEC) ; Télécom Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Télécom Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance (Lab-STICC) ; CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Télécom Bretagne - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - ENSTA Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Ecole Nationale d'Ingénieurs de Brest - CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - ENSTA Bretagne - Ecole Nationale d'Ingénieurs de Brest, Lab-STICC_TB_CACS_IAS ; Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance (Lab-STICC) ; CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Télécom Bretagne - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Télécom Bretagne - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Département Electronique (ELEC) ; Télécom Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance (Lab-STICC) ; CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Télécom Bretagne - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - ENSTA Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Ecole Nationale d'Ingénieurs de Brest - CNRS - ENSTA Bretagne - Ecole Nationale d'Ingénieurs de Brest, Equipe de Recherche sur les Relations Matrice Extracellulaire-Cellule (ERRMECE) ; EA 1391 - Université de Cergy Pontoise, XP-MED (XP-MED) ; entreprise, Laboratoire Electronique, Informatique et Image (LE2I) ; UMR CNRS 6306 - Université de Dijon, Laboratoire d'Informatique de Paris 6 (LIP6) ; CNRS - Université Pierre et Marie Curie (UPMC) - Paris VI, Laboratoire des Equipes Traitement des Images et du Signal, CNRS UMR 8051 (ETIS) ; ENSEA, Université de Cergy-Pontoise, Lewis, Noëlle, Renaud, Sylvie, Lagroye, Isabelle, ERIC, Mcadams, BOGONEZ-FRANCO, P, Noury, Norbert, SOULIER, Fabien, Bernard, Serge, LETHIAS, C, Lahuec, Cyril, ARZEL, Matthieu, AGNIEL, R, KELLOUCHE, S, BOISSIERE, M, Carreiras, Franck, PAUTHE, Emmanuel, Bonneau, M, Kang, Chantal, Binczak, Stéphane, PINNA, Andréa, Granado, Bertrand, Garda, Patrick, TEROSIET, M, GOGUIN, A, HISTACE, A, Romain, Olivier, Laboratoire de l'Intégration du Matériau au Système (IMS) ; UMR CNRS 5218 - Université de Bordeaux 1 - ENSEIRB-MATMECA, Institut de Nanotechnologie de Lyon (INL) ; Université de Lyon 1, Laboratoire d'Informatique, de Robotique et de Microélectronique de Montpellier (LIRMM) ; UMR CNRS 5506 - Université de Monpellier 2, Institut de Biologie et Chimie des Protéines (IBCP) ; Université de Lyon 1, Lab-STICC_TB_CACS_IAS ; Département Electronique (ELEC) ; Télécom Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Télécom Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance (Lab-STICC) ; CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Télécom Bretagne - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - ENSTA Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Ecole Nationale d'Ingénieurs de Brest - CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - ENSTA Bretagne - Ecole Nationale d'Ingénieurs de Brest, Lab-STICC_TB_CACS_IAS ; Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance (Lab-STICC) ; CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Télécom Bretagne - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Télécom Bretagne - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Département Electronique (ELEC) ; Télécom Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Laboratoire des sciences et techniques de l'information, de la communication et de la connaissance (Lab-STICC) ; CNRS - Université de Bretagne Occidentale (UBO) - Université de Bretagne Sud (UBS) - Télécom Bretagne - Institut Supérieur des Sciences et Technologies de Brest (ISSTB) - ENSTA Bretagne - Institut Mines-Télécom - PRES Université Européenne de Bretagne (UEB) - Ecole Nationale d'Ingénieurs de Brest - CNRS - ENSTA Bretagne - Ecole Nationale d'Ingénieurs de Brest, Equipe de Recherche sur les Relations Matrice Extracellulaire-Cellule (ERRMECE) ; EA 1391 - Université de Cergy Pontoise, XP-MED (XP-MED) ; entreprise, Laboratoire Electronique, Informatique et Image (LE2I) ; UMR CNRS 6306 - Université de Dijon, Laboratoire d'Informatique de Paris 6 (LIP6) ; CNRS - Université Pierre et Marie Curie (UPMC) - Paris VI, Laboratoire des Equipes Traitement des Images et du Signal, CNRS UMR 8051 (ETIS) ; ENSEA, Université de Cergy-Pontoise, Lewis, Noëlle, Renaud, Sylvie, Lagroye, Isabelle, ERIC, Mcadams, BOGONEZ-FRANCO, P, Noury, Norbert, SOULIER, Fabien, Bernard, Serge, LETHIAS, C, Lahuec, Cyril, ARZEL, Matthieu, AGNIEL, R, KELLOUCHE, S, BOISSIERE, M, Carreiras, Franck, PAUTHE, Emmanuel, Bonneau, M, Kang, Chantal, Binczak, Stéphane, PINNA, Andréa, Granado, Bertrand, Garda, Patrick, TEROSIET, M, GOGUIN, A, HISTACE, A, and Romain, Olivier

Abstract

National audience, This paper focuses on the study of fibrosis induced by an implanted medical device and explores the possibility of characterizing this process by in situ measurement of electrical impedance. The approach combines electrical and biological characterizations of fibrotic tissue, applied to electrodes implanted in animal models. A comparative study of electrical and biological parameters collected at the same time will enable the identification of an electrical marker of fibrosis development, which can be used for establishing a monitoring method. Adopting an interdisciplinary approach, intermediate embedded prototypes, autonomous and portable by animals, will be developed to confirm the feasibility of the continuous monitoring method and finally to propose architectural solutions (embedded computing and specific electrode) applicable to a wide variety of prosthetic implants. The paper will present some initial results on the electrical model of the fibrosis and the methodology used to obtain it.

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