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337 results on '"Kanemura, Takashi"'

1. ASO Visual Abstract: Clinical Impact of Conversion Surgery After Induction Therapy for Esophageal Cancer with Synchronous Distant Metastasis: A Multi-Institutional Retrospective Study

Author

Sugimura, Keijiro, Tanaka, Koji, Sugase, Takahito, Momose, Kota, Kanemura, Takashi, Yamashita, Kotaro, Makino, Tomoki, Shiraishi, Osamu, Motoori, Masaaki, Yamasaki, Makoto, Miyata, Hiroshi, Fujitani, Kazumasa, Yasuda, Takushi, Yano, Masahiko, Eguchi, Hidetoshi, and Doki, Yuichiro

Published
2024
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2. The clinical significance of the lymph node ratio as a recurrence indicator in ampullary cancer after curative pancreaticoduodenectomy

Author

Hasegawa, Shinichiro, Wada, Hiroshi, Kubo, Masahiko, Mukai, Yosuke, Mikamori, Manabu, Akita, Hirofumi, Matsuura, Norihiro, Kitakaze, Masatoshi, Masuike, Yasunori, Sugase, Takahito, Shinno, Naoki, Kanemura, Takashi, Hara, Hisashi, Sueda, Toshinori, Nishimura, Junichi, Yasui, Masayoshi, Omori, Takeshi, Miyata, Hiroshi, and Ohue, Masayuki

Published
2024
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4. Significance of Comprehensive Analysis of Preoperative Sarcopenia Based on Muscle Mass, Muscle Strength, and Physical Function for the Prognosis of Patients with Esophageal Cancer

Author

Kanemura, Takashi, Takeoka, Tomohira, Sugase, Takahito, Urakawa, Shinya, Masuike, Yasunori, Shinno, Naoki, Hara, Hisashi, Kitakaze, Masatoshi, Kubo, Masahiko, Mukai, Yousuke, Sueda, Toshinori, Hasegawa, Shinichiro, Akita, Hirofumi, Nishimura, Junichi, Wada, Hiroshi, Yasui, Masayoshi, Omori, Takeshi, and Miyata, Hiroshi

Published
2024
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5. Prognostic impact of dysphagia scores in patients with advanced resectable esophageal cancer who underwent radical esophagectomy after preoperative treatment

Author

Sugase, Takahito, Kanemura, Takashi, Matsuura, Norihiro, Ushimaru, Yuki, Masuike, Yasunori, Yanagimoto, Yoshitomo, Mori, Ryota, Kitakaze, Masatoshi, Amisaki, Masataka, Kubo, Masahiko, Mukai, Yosuke, Komatsu, Hisateru, Sueda, Toshinori, Kagawa, Yoshinori, Nishimura, Junichi, Wada, Hiroshi, Yasui, Masayoshi, Omori, Takeshi, and Miyata, Hiroshi

Published
2024
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6. A striking elevation of CA19-9 after preoperative therapy negates prognostic benefit from radical surgery in resectable and borderline resectable pancreatic cancer

Author

Akita, Hirofumi, Mukai, Yosuke, Kubo, Masahiko, Takahashi, Hidenori, Hasegawa, Shinichiro, Kitakaze, Masatoshi, Matsuura, Norihiro, Masuike, Yasunori, Sugase, Takahito, Shinno, Naoki, Kanemura, Takashi, Hara, Hisashi, Sueda, Toshinori, Nishimura, Junichi, Yasui, Masayoshi, Omori, Takeshi, Miyata, Hiroshi, Ohue, Masayuki, and Wada, Hiroshi

Published
2024
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8. ASO Author Reflections: Clinical Impact of Conversion Surgery After Induction Therapy for Esophageal Cancer with Synchronous Distant Metastasis: A Multi-institutional, Retrospective Study

Author

Sugimura, Keijiro, Tanaka, Koji, Sugase, Takahito, Momose, Kota, Kanemura, Takashi, Yamashita, Kotaro, Makino, Tomoki, Shiraishi, Osamu, Motoori, Masaaki, Yamasaki, Makoto, Miyata, Hiroshi, Fujitani, Kazumasa, Yasuda, Takushi, Yano, Masahiko, Eguchi, Hidetoshi, and Doki, Yuichiro

Published
2024
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9. DUPAN-II normalisation as a biological indicator during preoperative chemoradiation therapy for resectable and borderline resectable pancreatic cancer

Author

Hasegawa, Shinichiro, Takahashi, Hidenori, Akita, Hirofumi, Mukai, Yosuke, Mikamori, Manabu, Asukai, Kei, Yamada, Daisaku, Wada, Hiroshi, Fujii, Yoshiaki, Sugase, Takahito, Yamamoto, Masaaki, Takeoka, Tomohira, Shinno, Naoki, Hara, Hisashi, Kanemura, Takashi, Haraguchi, Naotsugu, Nishimura, Junichi, Matsuda, Chu, Yasui, Masayoshi, Omori, Takeshi, Miyata, Hiroshi, Ohue, Masayuki, Ishikawa, Osamu, and Sakon, Masato

Published
2023
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15. The DOLFIN method: a novel laparoscopic Billroth-I gastroduodenostomy for gastric cancer with duodenal invasion

Author

Shinno, Naoki, Omori, Takeshi, Hara, Hisashi, Yamamoto, Masaaki, Fujita, Kohei, Kanemura, Takashi, Takeoka, Tomohira, Sugase, Takahito, Yasui, Masayoshi, Matsuda, Chu, Wada, Hiroshi, Nishimura, Junichi, Haraguchi, Naotsugu, Akita, Hirofumi, Hasegawa, Shinichiro, Nakai, Nozomu, Asukai, Kei, Mukai, Yousuke, Miyata, Hiroshi, Ohue, Masayuki, and Sakon, Masato

Published
2022
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16. Laparoscopic Proximal Gastrectomy with Novel Valvuloplastic Esophagogastrostomy vs. Laparoscopic Total Gastrectomy for Stage I Gastric Cancer: a Propensity Score Matching Analysis

Author

Yamamoto, Masaaki, Omori, Takeshi, Shinno, Naoki, Hara, Hisashi, Fujii, Yoshiaki, Mukai, Yosuke, Sugase, Takahito, Takeoka, Tomohira, Asukai, Kei, Kanemura, Takashi, Hasegawa, Shinichiro, Akita, Hirofumi, Haraguchi, Naotsugu, Nishimura, Junichi, Wada, Hiroshi, Matsuda, Chu, Yasui, Masayoshi, Miyata, Hiroshi, and Ohue, Masayuki

Published
2022
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20. The clinical impact of modified transpancreatic mattress sutures with polyglactin 910 woven mesh on postoperative pancreatic fistula in distal pancreatectomy

Author

Imamura, Hiroki, Takahashi, Hidenori, Akita, Hirofumi, Wada, Hiroshi, Mukai, Yosuke, Asukai, Kei, Hasegawa, Shinichiro, Fujii, Yoshiaki, Sugase, Takahito, Yamamoto, Masaaki, Takeoka, Tomohira, Shinno, Naoki, Hara, Hisashi, Kanemura, Takashi, Haraguchi, Naotsugu, Nishimura, Junichi, Matsuda, Chu, Yasui, Masayoshi, Omori, Takeshi, Miyata, Hiroshi, Ohue, Masayuki, and Sakon, Masato

Published
2022
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21. Clinical importance of carcinoembryonic antigen messenger RNA level in peritoneal lavage fluids measured by transcription-reverse transcription concerted reaction for advanced gastric cancer in laparoscopic surgery

Author

Fujita, Kohei, Omori, Takeshi, Hara, Hisashi, Shinno, Naoki, Yamamoto, Masaaki, Aoyama, Yoshimasa, Sugimura, Keijiro, Kanemura, Takashi, Takeoka, Tomohira, Yasui, Masayoshi, Matsuda, Chu, Takahashi, Hidenori, Wada, Hiroshi, Nishimura, Junichi, Haraguchi, Naotsugu, Hasegawa, Shinichiro, Nakai, Nozomu, Asukai, Kei, Mukai, Yosuke, Miyata, Hiroshi, Ohue, Masayuki, and Sakon, Masato

Published
2022
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22. Postoperative aggressive diuresis prevents postoperative tissue edema and complications in patients undergoing distal pancreatectomy

Author

Imamura, Hiroki, Takahashi, Hidenori, Wada, Hiroshi, Mukai, Yosuke, Asukai, Kei, Hasegawa, Shinichiro, Yamamoto, Masaaki, Takeoka, Tomohira, Shinno, Naoki, Hara, Hisashi, Kanemura, Takashi, Nakai, Nozomu, Haraguchi, Naotsugu, Sugimura, Keijiro, Nishimura, Junichi, Matsuda, Chu, Yasui, Masayoshi, Omori, Takeshi, Miyata, Hiroshi, Ohue, Masayuki, and Sakon, Masato

Published
2022
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23. Robotic total gastrectomy with thrombectomy and portal vein reconstruction for gastric cancer and portal vein tumor thrombus

Author

Yamamoto, Masaaki, Omori, Takeshi, Shinno, Naoki, Hara, Hisashi, Mukai, Yosuke, Sugase, Takahito, Takeoka, Tomohira, Asukai, Kei, Kanemura, Takashi, Nakai, Nozomu, Hasegawa, Shinichiro, Sugimura, Keijiro, Akita, Hirofumi, Haraguchi, Naotsugu, Nishimura, Junichi, Wada, Hiroshi, Takahashi, Hidenori, Matsuda, Chu, Yasui, Masayoshi, Miyata, Hiroshi, and Ohue, Masayuki

Published
2022
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25. Prognostic impact of nodal status and lymphovascular invasion in patients undergoing neoadjuvant chemotherapy for esophageal squamous cell carcinoma.

Author

Miyata, Hiroshi, Sugimura, Keijirou, Kanemura, Takashi, Takeoka, Tomohira, Sugase, Takahito, Yasui, Masayoshi, Nishimura, Junichi, Wada, Hiroshi, Akita, Hiroshi, Yamamoto, Masaaki, Hara, Hisashi, Shinno, Naoki, Omori, Takeshi, and Yano, Masahiko

Subjects
NEOADJUVANT chemotherapy, CANCER prognosis, PROGNOSIS, OVERALL survival, SQUAMOUS cell carcinoma, ESOPHAGEAL cancer
Abstract

Nodal status is well known to be the most important prognostic factor for esophageal cancer patients, even if they are treated with neoadjuvant therapy. To establish an optimal postoperative adjuvant strategy for patients, we aimed to more accurately predict the prognosis of patients and systemic recurrence by using clinicopathological factors, including nodal status, in patients with esophageal cancer who received neoadjuvant chemotherapy. The clinicopathological factors associated with survival and systemic recurrence were investigated in 488 patients with esophageal squamous cell carcinoma who received neoadjuvant chemotherapy. Overall survival differed according to tumor depth, nodal status, tumor regression, and lymphovascular (LV) invasion. In the multivariate analysis, nodal status and LV invasion were identified as independent prognostic factors (P  < 0.0001, P  = 0.0008). Nodal status was also identified as an independent factor associated with systemic recurrence, although LV invasion was a borderline factor (P  = 0.066). In each pN stage, patients with LV invasion showed significantly worse overall survival than those without LV invasion (pN0: P  = 0.036, pN1: P  = 0.0044, pN2: P  = 0.0194, pN3: P  = 0.0054). Patients with LV invasion were also more likely to have systemic, and any recurrence than those without LV invasion in each pN stage. Pathological nodal status and LV invasion were the most important predictors of survival and systemic recurrence in patients with esophageal cancer who underwent neoadjuvant chemotherapy followed by surgery. This finding could provide useful information about selecting candidates for adjuvant therapy among these patients. Our analysis showed that LV invasion was an independent prognostic factor in patients with esophageal cancer who underwent neoadjuvant chemotherapy and that combining LV invasion with pathological nodal status makes it possible to stratify the prognosis in those patients. [ABSTRACT FROM AUTHOR]

Published
2024
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26. Clinical Impact of Early Tumour Shrinkage in Metastatic or Unresectable Oesophageal Cancer Treated with Pembrolizumab plus Chemotherapy.

Author

Sugase, Takahito, Kanemura, Takashi, Takeoka, Tomohira, Matsuura, Norihiro, Masuike, Yasunori, Shinno, Naoki, Hara, Hisashi, Omori, Takeshi, Kitakaze, Masatoshi, Kubo, Masahiko, Mukai, Yosuke, Sueda, Toshinori, Hasegawa, Shinichiro, Akita, Hirofumi, Nishimura, Junichi, Wada, Hiroshi, Yasui, Masayoshi, and Miyata, Hiroshi

Subjects
*THERAPEUTIC use of monoclonal antibodies, *PREDICTIVE tests, *IMMUNOTHERAPY, *ESOPHAGEAL tumors, *TREATMENT effectiveness, *DESCRIPTIVE statistics, *MULTIVARIATE analysis, *METASTASIS, *CANCER chemotherapy, *LOG-rank test, *PROGRAMMED cell death 1 receptors, *COMBINED modality therapy, *PROGRESSION-free survival, *OVERALL survival
Abstract

Introduction: Metastatic or unresectable locally advanced oesophageal cancer remains a disease with high mortality. More recently, pembrolizumab plus chemotherapy has been indicated as the first-line treatment for those patients, but the predictive factors for treatment efficacy remain controversial. This study investigated the clinical utility of early tumour shrinkage (ETS) and depth of response (DpR) in metastatic or unresectable oesophageal cancer treated with pembrolizumab plus CF therapy. Methods: ETS and DpR, defined as the percent decreases at the second evaluation and the percentage of the maximal tumour shrinkage during treatment, were measured in 53 eligible patients. The ETS and DpR cut-off values were 20% and 30%, respectively, based on survival outcomes. Results: Twenty-seven patients (51%) were treatment naïve, while 26 (49%) had received any treatment before initiating pembrolizumab plus CF therapy. The median progression-free survival (PFS) and overall survival for ETS ≥20% and <20% were 12.7 and 5.5 months and 14.4 and 8.2 months and 12.7 and 4.9 months and 14.4 and 8.0 months for DpR ≥30% and <30%, respectively. ETS <20% showed early tumour growth, whereas ETS ≥20% had a good response rate with sufficient longer response duration. In addition, an ETS cut-off of 20% predicted the best overall response and was not associated with prior treatment. In multivariable analysis, ETS ≥20% and DpR ≥30% were independent factors of longer PFS. Conclusion: Our findings suggest that an ETS is a promising on-treatment marker for early prediction of further sensitivity to pembrolizumab plus CF therapy. [ABSTRACT FROM AUTHOR]

Published
2024
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27. Demonstration of recycling process for GaN substrates using laser slicing technique towards cost reduction of GaN vertical power MOSFETs

Author

Ishida, Takashi, primary, Ushijima, Takashi, additional, Nakabayashi, Shosuke, additional, Kato, Kozo, additional, Koyama, Takayuki, additional, Nagasato, Yoshitaka, additional, Ohara, Junji, additional, Hoshi, Shinichi, additional, Nagaya, Masatake, additional, Hara, Kazukuni, additional, Kanemura, Takashi, additional, Taki, Masato, additional, Yui, Toshiki, additional, Hara, Keisuke, additional, Kawaguchi, Daisuke, additional, Kuno, Koji, additional, Osajima, Tetsuya, additional, Kojima, Jun, additional, Uesugi, Tsutomu, additional, Tanaka, Atsushi, additional, Sasaoka, Chiaki, additional, Onda, Shoichi, additional, and Suda, Jun, additional

Published
2024
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28. Clinical Impact of Early Tumour Shrinkage in Metastatic or Unresectable Oesophageal Cancer Treated with Pembrolizumab plus Chemotherapy

Author

Sugase, Takahito, primary, Kanemura, Takashi, additional, Takeoka, Tomohira, additional, Matsuura, Norihiro, additional, Masuike, Yasunori, additional, Shinno, Naoki, additional, Hara, Hisashi, additional, Omori, Takeshi, additional, Kitakaze, Masatoshi, additional, Kubo, Masahiko, additional, Mukai, Yosuke, additional, Sueda, Toshinori, additional, Hasegawa, Shinichiro, additional, Akita, Hirofumi, additional, Nishimura, Junichi, additional, Wada, Hiroshi, additional, Yasui, Masayoshi, additional, and Miyata, Hiroshi, additional

Published
2023
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29. Laparoscopic-assisted disinvagination and polypectomy for multiple intussusceptions induced by small intestinal polyps in patients with Peutz-Jeghers syndrome: a case report

Author

Yamamoto, Masaaki, Iwamoto, Kazuya, Suzuki, Rei, Mukai, Yosuke, Takeoka, Tomohira, Asukai, Kei, Shinno, Naoki, Hara, Hisashi, Kanemura, Takashi, Nakai, Nozomu, Hasegawa, Shinichiro, Sugimura, Keijiro, Haraguchi, Naotsugu, Nishimura, Junichi, Wada, Hiroshi, Takahashi, Hidenori, Matsuda, Chu, Yasui, Masayoshi, Omori, Takeshi, Miyata, Hiroshi, Ohue, Masayuki, and Murata, Masaru

Published
2021
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31. Estimation of Influence on Carbon Vacancy Regarding 4H-SiC Substrate Grown by HTCVD Method

Author

Uehigashi, Hideyuki, Okamoto, Takeshi, Horiai, Akiyoshi, Fujibayashi, Hiroaki, Kanda, Takahiro, Kanemura, Takashi, and Tsuruta, Kazuhiro

Abstract

In order to increase productivity and reduce the cost of wafers, we have developed a high temperature chemical vapor deposition (HTCVD) method that can realize the high-speed growth of 4H-SiC crystals. Tokuda et al. reported an interesting study in which the carrier lifetime of a substrate grown by HTCVD (HTCVD substrate) was considerably shorter than that of the substrate grown by physical vapor transport (PVT); moreover, bipolar degradation was highly suppressed when the HTCVD substrate was applied to PiN diodes [1]. Herein, we demonstrate that the short carrier lifetime of the HTCVD substrate is mainly attributable to the carbon vacancy (VC) and that VC particularly diffuses from the HTCVD substrate to the epitaxial layer.

Published
2024
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32. Clinicopathological Characteristics and Survival Outcomes in Patients with Advanced Esophageal Squamous Cell Carcinoma Who Were Intraoperatively Diagnosed Non-Curative.

Author

Sugase, Takahito, Kanemura, Takashi, Takeoka, Tomohira, Sugimura, Keijiro, Yamamoto, Masaaki, Shinno, Naoki, Hara, Hisashi, Omori, Takeshi, Mukai, Yosuke, Mikamori, Manabu, Hasegawa, Shinichiro, Haraguchi, Naotsugu, Akita, Hirofumi, Nishimura, Junichi, Wada, Hiroshi, Matsuda, Chu, Yasui, Masayoshi, and Miyata, Hiroshi

Subjects
*SQUAMOUS cell carcinoma, *CANCER invasiveness, *TREATMENT effectiveness, *DESCRIPTIVE statistics, *CHEMORADIOTHERAPY, *CHI-squared test, *MANN Whitney U Test, *SURGICAL complications, *METASTASIS, *KAPLAN-Meier estimator, *DATA analysis software, *ESOPHAGEAL cancer, *OVERALL survival, *PROPORTIONAL hazards models, DIGESTIVE organ surgery
Abstract

Introduction: Curative esophagectomy is not always possible in patients with locally advanced esophageal cancer. However, few studies have investigated patients who underwent non-curative surgery with intraoperative judgment. This study aimed to investigate patient characteristics and clinical outcomes for patients undergoing non-curative surgery and compare them between non-resectional and non-radical surgery. Methods: Among 989 consecutive patients with thoracic esophageal squamous cell carcinoma who were preoperatively expected for curative esophagectomy, 66 who were eligible for non-curative surgery were included in this study. Results: Intraoperative diagnosis of T4b accounted for 93% of the reasons for the failure of curative surgery. In those patients, esophageal cancer locally invaded into the aortobronchial constriction (70%), trachea (25%), or pulmonary vein (5%). Lymph node metastasis mainly invaded into the trachea (50%) or bronchus (28%). The overall survival of patients with non-curative surgery was 51.5%, 25.7%, and 10.4% at 6, 12, and 24 months after surgery, respectively. Although there were no differences in preoperative patient characteristics between non-resectional and non-radical surgery, distant metastasis, especially pleural dissemination, was significantly observed in T4b patients due to esophageal cancer with non-radical surgery than those with non-resectional surgery (35% vs. 15%, p = 0.002). Even in patients with non-curative surgery, R1 resection and postoperative chemoradiotherapy were identified as independent factors for survival 1 year after surgery (p = 0.047, and 0.019). Conclusions: T4b tumor located in aortobronchial constriction or trachea/bronchus makes it difficult to diagnose whether it is resectable or unresectable. Moreover, surgical procedures and perioperative treatment were deeply associated with the clinical outcomes. [ABSTRACT FROM AUTHOR]

Published
2024
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33. Significance of Comprehensive Analysis of Preoperative Sarcopenia Based on Muscle Mass, Muscle Strength, and Physical Function for the Prognosis of Patients with Esophageal Cancer

Author

Kanemura, Takashi, primary, Takeoka, Tomohira, additional, Sugase, Takahito, additional, Urakawa, Shinya, additional, Masuike, Yasunori, additional, Shinno, Naoki, additional, Hara, Hisashi, additional, Kitakaze, Masatoshi, additional, Kubo, Masahiko, additional, Mukai, Yousuke, additional, Sueda, Toshinori, additional, Hasegawa, Shinichiro, additional, Akita, Hirofumi, additional, Nishimura, Junichi, additional, Wada, Hiroshi, additional, Yasui, Masayoshi, additional, Omori, Takeshi, additional, and Miyata, Hiroshi, additional

Published
2023
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34. Clinicopathological Characteristics and Survival Outcomes in Patients with Advanced Esophageal Squamous Cell Carcinoma Who Were Intraoperatively Diagnosed Non-Curative

Author

Sugase, Takahito, primary, Kanemura, Takashi, additional, Takeoka, Tomohira, additional, Sugimura, Keijiro, additional, Yamamoto, Masaaki, additional, Shinno, Naoki, additional, Hara, Hisashi, additional, Omori, Takeshi, additional, Mukai, Yosuke, additional, Mikamori, Manabu, additional, Hasegawa, Shinichiro, additional, Haraguchi, Naotsugu, additional, Akita, Hirofumi, additional, Nishimura, Junichi, additional, Wada, Hiroshi, additional, Matsuda, Chu, additional, Yasui, Masayoshi, additional, and Miyata, Hiroshi, additional

Published
2023
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35. Adjuvant Chemotherapy With S-1 Plus DocetaxelVersusS-1 Plus Oxaliplatin in Stage III Gastric Cancer

Author

YAMAMOTO, MASAAKI, primary, OMORI, TAKESHI, additional, SHINNO, NAOKI, additional, HARA, HISASHI, additional, MUKAI, YOSUKE, additional, SUGASE, TAKAHITO, additional, TAKEOKA, TOMOHIRA, additional, MIKAMORI, MANABU, additional, KANEMURA, TAKASHI, additional, HASEGAWA, SHINICHIRO, additional, AKITA, HIROFUMI, additional, HARAGUCHI, NAOTSUGU, additional, NISHIMURA, JUNICHI, additional, WADA, HIROSHI, additional, MATSUDA, CHU, additional, YASUI, MASAYOSHI, additional, MIYATA, HIROSHI, additional, and OHUE, MASAYUKI, additional

Published
2023
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36. Clinical Impact of Enhanced Recovery After Esophagectomy in Patients With Esophageal Cancer

Author

SUGASE, TAKAHITO, primary, KANEMURA, TAKASHI, additional, TAKEOKA, TOMOHIRA, additional, URAKAWA, SHINYA, additional, SUGIMURA, KEIJIRO, additional, MASUIKE, YASUNORI, additional, SHINNO, NAOKI, additional, HARA, HISASHI, additional, OMORI, TAKESHI, additional, KITAKAZE, MASATOSHI, additional, KUBO, MASAHIKO, additional, MUKAI, YOSUKE, additional, SUEDA, TOSHINORI, additional, HASEGAWA, SHINICHIRO, additional, AKITA, HIROFUMI, additional, NISHIMURA, JUNICHI, additional, WADA, HIROSHI, additional, YASUI, MASAYOSHI, additional, and MIYATA, HIROSHI, additional

Published
2023
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40. Density and maturity of peritumoral tertiary lymphoid structures in oesophageal squamous cell carcinoma predicts patient survival and response to immune checkpoint inhibitors

Author

Hayashi, Yoshinori, primary, Makino, Tomoki, additional, Sato, Eiichi, additional, Ohshima, Kenji, additional, Nogi, Yuya, additional, Kanemura, Takashi, additional, Honma, Keiichiro, additional, Yamashita, Kotaro, additional, Saito, Takuro, additional, Tanaka, Koji, additional, Yamamoto, Kazuyoshi, additional, Takahashi, Tsuyoshi, additional, Kurokawa, Yukinori, additional, Miyata, Hiroshi, additional, Nakajima, Kiyokazu, additional, Wada, Hisashi, additional, Morii, Eiichi, additional, Eguchi, Hidetoshi, additional, and Doki, Yuichiro, additional

Published
2023
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42. The utility of bile juice culture analysis for the management of postoperative infection after pancreaticoduodenectomy

Author

Asukai, Kei, primary, Akita, Hirofumi, additional, Mukai, Yosuke, additional, Mikamori, Manabu, additional, Hasegawa, Shinichiro, additional, Fujii, Yoshiaki, additional, Sugase, Takahito, additional, Yamamoto, Masaaki, additional, Takeoka, Tomohira, additional, Shinno, Naoki, additional, Hara, Hisashi, additional, Kanemura, Takashi, additional, Haraguchi, Naotsugu, additional, Nishimura, Junichi, additional, Matsuda, Chu, additional, Yasui, Masayoshi, additional, Omori, Takeshi, additional, Miyata, Hiroshi, additional, Ohue, Masayuki, additional, Sakon, Masato, additional, Wada, Hiroshi, additional, and Takahashi, Hidenori, additional

Published
2022
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44. Modified Collard technique is more effective than circular stapled for cervical esophagogastric anastomosis in prevention of anastomotic stricture: a propensity score-matched study

Author

Takeoka, Tomohira, primary, Miyata, Hiroshi, additional, Sugimura, Keijiro, additional, Kanemura, Takashi, additional, Sugase, Takahito, additional, Yamamoto, Masaaki, additional, Shinno, Naoki, additional, Hara, Hisashi, additional, Fujii, Yoshiaki, additional, Mukai, Yosuke, additional, Asukai, Kei, additional, Mikamori, Manabu, additional, Hasegawa, Shinichiro, additional, Akita, Hirofumi, additional, Haraguchi, Naotsugu, additional, Nishimura, Junichi, additional, Wada, Hiroshi, additional, Matsuda, Chu, additional, Omori, Takeshi, additional, Yasui, Masayoshi, additional, Ohue, Masayuki, additional, and Yano, Masahiko, additional

Published
2022
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46. Significance of dissection in each regional lymph-node station of esophageal cancer based on efficacy index and recurrence patterns after curative esophagectomy.

Author

Kanemura, Takashi, Miyata, Hiroshi, Takeoka, Tomohira, Sugase, Takahito, Sugimura, Keijiro, Yamashita, Kotaro, Tanaka, Koji, Makino, Tomoki, Ota, Mitsuhiko, Yagi, Koichi, Toh, Yasushi, Seto, Yasuyuki, and Doki, Yuichiro

Abstract

Background: The optimal extent of lymph-node (LN) dissection in esophageal cancer has not been established. Although the frequency and patterns of recurrence in each regional LN station after radical dissection are important in determining the regional LNs of thoracic esophageal cancer to be routinely dissected, this information has not been investigated sufficiently. We studied the significance of dissection at each LN station based on their recurrence patterns. Methods: Six hundred and twelve patients with esophageal cancer who underwent curative esophagectomy were studied. The incidence and pattern of recurrence (systemic or non-systemic) at each regional LN station were analyzed. To compare the significance of dissection among regional LNs, the efficacy index (EI) was also calculated. Results: Regional LN recurrence was diagnosed in 101 (16.5%) patients. Among the regional LNs, recurrent laryngeal nerve, paraesophageal, and perigastric LNs showed higher EIs (3.1–6.7). Pretracheal and posterior thoracic para-aortic LNs showed low EIs (0–0.2). Supraclavicular LNs had moderate EIs (1.7–2.0). The recurrence rate was highest in the pretracheal LN, followed by the supraclavicular LNs. The majority (81.8%) of the pretracheal LN had a systemic recurrence, while about half (right: 60.0%, left: 43.8%) of the supraclavicular LNs had a systemic recurrence. Conclusion: Due to the high incidence of systemic recurrence or low EI for pretracheal and posterior thoracic para-aortic LNs, we suggest that these LN stations be regarded as non-regional LNs and be excluded from routine dissection. Supraclavicular LNs may also be excluded from routinely dissected stations. [ABSTRACT FROM AUTHOR]

Published
2023
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48. Antemortem diagnosis of pulmonary tumor thrombotic microangiopathy associated with gastric cancer and response to immediate chemotherapy

Author

Fujita, Kohei, primary, Omori, Takeshi, additional, Hara, Hisashi, additional, Shinno, Naoki, additional, Yamamoto, Masaaki, additional, Kanemura, Takashi, additional, Takeoka, Tomohira, additional, Sugase, Takahito, additional, Miyata, Hiroshi, additional, Ohue, Masayuki, additional, and Sakon, Masato, additional

Published
2022
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50. Long‐term changes in bone mineral density in postoperative patients with esophageal cancer.

Author

Sugase, Takahito, Sugimura, Keijiro, Kanemura, Takashi, Takeoka, Tomohira, Yamamoto, Masaaki, Shinno, Naoki, Hara, Hisashi, Omori, Takeshi, Yasui, Masayoshi, and Miyata, Hiroshi

Abstract

Aim: The aim of this study was to investigate long‐term changes in bone mineral density (BMD) after esophagectomy, identify the risk factors for postoperative osteoporosis in patients with esophageal cancer and survival outcomes related to osteoporosis. Methods: We retrospectively evaluated BMD changes for 197 consecutive patients with thoracic esophageal cancer who were disease‐free for 5 years after radical esophagectomy. Osteoporosis was diagnosed using computed tomography with an L1 attenuation threshold of ≤110 HU. Survival analysis was performed on 381 consecutive patients with 5‐year follow‐up after radical esophagectomy. Results: BMD decreased annually after esophagectomy. The median attenuation (HU) was 134.2 before surgery and 135.2, 127.4, 123.3, 115.2, 105.6, and 102.4 at 6 months and 1, 2, 3, 4, and 5 years after surgery, respectively. Osteoporosis was diagnosed in 25.9% patients before surgery and 23.3%, 29.4%, 40.1%, 46.7%, 54.8%, and 60.4% patients with osteoporosis were observed at 6 months and 1, 2, 3, 4, and 5 years after surgery, respectively. Postoperative BMD did not decrease in patients aged ≤54 years, those who had never been smokers, and those with no weight loss after esophagectomy. Multivariate analysis identified that age (≥65 years) at surgery and smoking history were independent risk factors for osteoporosis at 5 years after esophagectomy. Patients with preoperative osteoporosis tended to have worse prognosis in disease‐free survival and overall survival than those without osteoporosis, who were more likely to die due to non‐esophageal cancer. Conclusion: Esophageal cancer survivors are more likely to develop osteoporosis after esophagectomy, and preoperative osteoporosis might be associated with prognosis. [ABSTRACT FROM AUTHOR]

Published
2023
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