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259 results on '"Kandela, Irawati"'

1. Targeting EphA2 in Bladder Cancer Using a Novel Antibody-Directed Nanotherapeutic.

Author

Kamoun, Walid, Swindell, Elden, Pien, Christine, Luus, Lia, Cain, Jason, Pham, Minh, Kandela, Irawati, Huang, Zhaohua Richard, Tipparaju, Suresh K, Koshkaryev, Alexander, Askoxylakis, Vasileios, Kirpotin, Dmitri B, Bloom, Troy, Mino-Kenudson, Mari, Marks, James D, Zalutskaya, Alena, Bshara, Wiam, Morrison, Carl, and Drummond, Daryl C

Subjects
EphA2, antibody directed nanotherapeutic, bladder cancer, immunoliposomes, liposomes, nanocarrier, Pharmacology and Pharmaceutical Sciences
Abstract

Ephrin receptor A2 (EphA2) is a member of the Ephrin/Eph receptor cell-to-cell signaling family of molecules, and it plays a key role in cell proliferation, differentiation, and migration. EphA2 is overexpressed in a broad range of cancers, and its expression is in many cases associated with poor prognosis. We recently developed a novel EphA2-targeting antibody-directed nanotherapeutic encapsulating a labile prodrug of docetaxel (EphA2-ILs-DTXp) for the treatment of EphA2-expressing malignancies. Here, we characterized the expression of EphA2 in bladder cancer using immunohistochemistry in 177 human bladder cancer samples and determined the preclinical efficacy of EphA2-ILs-DTXp in four EphA2-positive patient-derived xenograft (PDX) models of the disease, either as a monotherapy, or in combination with gemcitabine. EphA2 expression was detected in 80-100% of bladder cancer samples and correlated with shorter patient survival. EphA2 was found to be expressed in tumor cells and/or tumor-associated blood vessels in both primary and metastatic lesions with a concordance rate of approximately 90%. The EphA2-targeted antibody-directed nanotherapeutic EphA2-ILs-DTXp controlled tumor growth, mediated greater regression, and was more active than free docetaxel at equitoxic dosing in all four EphA2-positive bladder cancer PDX models. Combination of EphA2-ILs-DTXp and gemcitabine in one PDX model led to improved tumor growth control compared to monotherapies or the combination of free docetaxel and gemcitabine. These data demonstrating the prevalence of EphA2 in bladder cancers and efficacy of EphA2-ILs-DTXp in PDX models support the clinical exploration of EphA2 targeting in bladder cancer.

Published
2020

2. Ecoresorbable and bioresorbable microelectromechanical systems

Author

Yang, Quansan, Liu, Tzu-Li, Xue, Yeguang, Wang, Heling, Xu, Yameng, Emon, Bashar, Wu, Mingzheng, Rountree, Corey, Wei, Tong, Kandela, Irawati, Haney, Chad R., Brikha, Anlil, Stepien, Iwona, Hornick, Jessica, Sponenburg, Rebecca A., Cheng, Christina, Ladehoff, Lauren, Chen, Yitong, Hu, Ziying, Wu, Changsheng, Han, Mengdi, Torkelson, John M., Kozorovitskiy, Yevgenia, Saif, M. Taher A., Huang, Yonggang, Chang, Jan-Kai, and Rogers, John A.

Published
2022
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3. Photocurable bioresorbable adhesives as functional interfaces between flexible bioelectronic devices and soft biological tissues

Author

Yang, Quansan, Wei, Tong, Yin, Rose T., Wu, Mingzheng, Xu, Yameng, Koo, Jahyun, Choi, Yeon Sik, Xie, Zhaoqian, Chen, Sheena W., Kandela, Irawati, Yao, Shenglian, Deng, Yujun, Avila, Raudel, Liu, Tzu-Li, Bai, Wubin, Yang, Yiyuan, Han, Mengdi, Zhang, Qihui, Haney, Chad R., Benjamin Lee, K., Aras, Kedar, Wang, Tong, Seo, Min-Ho, Luan, Haiwen, Lee, Seung Min, Brikha, Anlil, Ghoreishi-Haack, Nayereh, Tran, Lori, Stepien, Iwona, Aird, Fraser, Waters, Emily A., Yu, Xinge, Banks, Anthony, Trachiotis, Gregory D., Torkelson, John M., Huang, Yonggang, Kozorovitskiy, Yevgenia, Efimov, Igor R., and Rogers, John A.

Published
2021
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6. Bioresorbable photonic devices for the spectroscopic characterization of physiological status and neural activity

Author

Bai, Wubin, Shin, Jiho, Fu, Ruxing, Kandela, Irawati, Lu, Di, Ni, Xiaoyue, Park, Yoonseok, Liu, Zhonghe, Hang, Tao, Wu, Di, Liu, Yonghao, Haney, Chad R., Stepien, Iwona, Yang, Quansan, Zhao, Jie, Nandoliya, Khizar Rehan, Zhang, Hao, Sheng, Xing, Yin, Lan, MacRenaris, Keith, Brikha, Anlil, Aird, Fraser, Pezhouh, Maryam, Hornick, Jessica, Zhou, Weidong, and Rogers, John A.

Published
2019
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8. Bioresorbable pressure sensors protected with thermally grown silicon dioxide for the monitoring of chronic diseases and healing processes

Author

Shin, Jiho, Yan, Ying, Bai, Wubin, Xue, Yeguang, Gamble, Paul, Tian, Limei, Kandela, Irawati, Haney, Chad R., Spees, William, Lee, Yechan, Choi, Minseok, Ko, Jonathan, Ryu, Hangyu, Chang, Jan-Kai, Pezhouh, Maryam, Kang, Seung-Kyun, Won, Sang Min, Yu, Ki Jun, Zhao, Jianing, Lee, Yoon Kyeung, MacEwan, Matthew R., Song, Sheng-Kwei, Huang, Yonggang, Ray, Wilson Z., and Rogers, John A.

Published
2019
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10. Data from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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11. Supplementary Table 10 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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12. Supplementary Table 8 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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13. Supplementary Table 7 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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14. Supplementary Table 2 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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15. Supplementary Table 6 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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16. Supplementary Table 9 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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17. Supplementary Table 4 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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18. Supplementary Table 5 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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19. Supplementary Figures S1-15 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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20. Supplementary Table 3 from Posttranslational Regulation of the Exon Skipping Machinery Controls Aberrant Splicing in Leukemia

Author

Zhou, Yalu, primary, Han, Cuijuan, primary, Wang, Eric, primary, Lorch, Adam H., primary, Serafin, Valentina, primary, Cho, Byoung-Kyu, primary, Gutierrez Diaz, Blanca T., primary, Calvo, Julien, primary, Fang, Celestia, primary, Khodadadi-Jamayran, Alireza, primary, Tabaglio, Tommaso, primary, Marier, Christian, primary, Kuchmiy, Anna, primary, Sun, Limin, primary, Yacu, George, primary, Filip, Szymon K., primary, Jin, Qi, primary, Takahashi, Yoh-Hei, primary, Amici, David R., primary, Rendleman, Emily J., primary, Rawat, Radhika, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Zhang, Cheng, primary, Li, Hu, primary, Kandela, Irawati, primary, Politanska, Yuliya, primary, Abdala-Valencia, Hiam, primary, Mendillo, Marc L., primary, Zhu, Ping, primary, Palhais, Bruno, primary, Van Vlierberghe, Pieter, primary, Taghon, Tom, primary, Aifantis, Iannis, primary, Goo, Young Ah, primary, Guccione, Ernesto, primary, Heguy, Adriana, primary, Tsirigos, Aristotelis, primary, Wee, Keng Boon, primary, Mishra, Rama K., primary, Pflumio, Francoise, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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24. Supplementary Table 2 from USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

Author

Jin, Qi, primary, Martinez, Carlos A., primary, Arcipowski, Kelly M., primary, Zhu, Yixing, primary, Gutierrez-Diaz, Blanca T., primary, Wang, Kenneth K., primary, Johnson, Megan R., primary, Volk, Andrew G., primary, Wang, Feng, primary, Wu, Jian, primary, Grove, Charles, primary, Wang, Hui, primary, Sokirniy, Ivan, primary, Thomas, Paul M., primary, Goo, Young Ah, primary, Abshiru, Nebiyu A., primary, Hijiya, Nobuko, primary, Peirs, Sofie, primary, Vandamme, Niels, primary, Berx, Geert, primary, Goosens, Steven, primary, Marshall, Stacy A., primary, Rendleman, Emily J., primary, Takahashi, Yoh-hei, primary, Wang, Lu, primary, Rawat, Radhika, primary, Bartom, Elizabeth T., primary, Collings, Clayton K., primary, Van Vlierberghe, Pieter, primary, Strikoudis, Alexandros, primary, Kelly, Stephen, primary, Ueberheide, Beatrix, primary, Mantis, Christine, primary, Kandela, Irawati, primary, Bourquin, Jean-Pierre, primary, Bornhauser, Beat, primary, Serafin, Valentina, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, Kelleher, Neil L., primary, Weinstock, Joseph, primary, Kumar, Suresh, primary, Crispino, John D., primary, Shilatifard, Ali, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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26. Figures S1-17 plus legends from USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

Author

Jin, Qi, primary, Martinez, Carlos A., primary, Arcipowski, Kelly M., primary, Zhu, Yixing, primary, Gutierrez-Diaz, Blanca T., primary, Wang, Kenneth K., primary, Johnson, Megan R., primary, Volk, Andrew G., primary, Wang, Feng, primary, Wu, Jian, primary, Grove, Charles, primary, Wang, Hui, primary, Sokirniy, Ivan, primary, Thomas, Paul M., primary, Goo, Young Ah, primary, Abshiru, Nebiyu A., primary, Hijiya, Nobuko, primary, Peirs, Sofie, primary, Vandamme, Niels, primary, Berx, Geert, primary, Goosens, Steven, primary, Marshall, Stacy A., primary, Rendleman, Emily J., primary, Takahashi, Yoh-hei, primary, Wang, Lu, primary, Rawat, Radhika, primary, Bartom, Elizabeth T., primary, Collings, Clayton K., primary, Van Vlierberghe, Pieter, primary, Strikoudis, Alexandros, primary, Kelly, Stephen, primary, Ueberheide, Beatrix, primary, Mantis, Christine, primary, Kandela, Irawati, primary, Bourquin, Jean-Pierre, primary, Bornhauser, Beat, primary, Serafin, Valentina, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, Kelleher, Neil L., primary, Weinstock, Joseph, primary, Kumar, Suresh, primary, Crispino, John D., primary, Shilatifard, Ali, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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27. Supplementary Table 1 from USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

Author

Jin, Qi, primary, Martinez, Carlos A., primary, Arcipowski, Kelly M., primary, Zhu, Yixing, primary, Gutierrez-Diaz, Blanca T., primary, Wang, Kenneth K., primary, Johnson, Megan R., primary, Volk, Andrew G., primary, Wang, Feng, primary, Wu, Jian, primary, Grove, Charles, primary, Wang, Hui, primary, Sokirniy, Ivan, primary, Thomas, Paul M., primary, Goo, Young Ah, primary, Abshiru, Nebiyu A., primary, Hijiya, Nobuko, primary, Peirs, Sofie, primary, Vandamme, Niels, primary, Berx, Geert, primary, Goosens, Steven, primary, Marshall, Stacy A., primary, Rendleman, Emily J., primary, Takahashi, Yoh-hei, primary, Wang, Lu, primary, Rawat, Radhika, primary, Bartom, Elizabeth T., primary, Collings, Clayton K., primary, Van Vlierberghe, Pieter, primary, Strikoudis, Alexandros, primary, Kelly, Stephen, primary, Ueberheide, Beatrix, primary, Mantis, Christine, primary, Kandela, Irawati, primary, Bourquin, Jean-Pierre, primary, Bornhauser, Beat, primary, Serafin, Valentina, primary, Bresolin, Silvia, primary, Paganin, Maddalena, primary, Accordi, Benedetta, primary, Basso, Giuseppe, primary, Kelleher, Neil L., primary, Weinstock, Joseph, primary, Kumar, Suresh, primary, Crispino, John D., primary, Shilatifard, Ali, primary, and Ntziachristos, Panagiotis, primary

Published
2023
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28. Table S3. Gene Set Enrichment Analysis (GSEA) C2 gene sets. from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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29. Data from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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30. Table S2. Gene Set Enrichment Analysis (GSEA) C5 GO gene sets. from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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31. Figure S1. Quantitative RT-PCR validation of ixazomib genes. from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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32. Supplementary Legends from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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33. Table S4. Key genes involved with anti-proteasomal response in L428 cells. from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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34. Figure S3. Inhibition of histone acetyl transferase (HAT). from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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35. Table S1. Common upstream regulators. from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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36. Table S5. DAVID functional classification of ixazomib genes. from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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37. Figure S2. Network representation of Gene Set Enrichment Analysis (GSEA) for Biological pathways. from Proteasomal Inhibition by Ixazomib Induces CHK1 and MYC-Dependent Cell Death in T-cell and Hodgkin Lymphoma

Author

Ravi, Dashnamoorthy, primary, Beheshti, Afshin, primary, Abermil, Nasséra, primary, Passero, Frank, primary, Sharma, Jaya, primary, Coyle, Michael, primary, Kritharis, Athena, primary, Kandela, Irawati, primary, Hlatky, Lynn, primary, Sitkovsky, Michail V., primary, Mazar, Andrew, primary, Gartenhaus, Ronald B., primary, and Evens, Andrew M., primary

Published
2023
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39. Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Author

Jin, Qi, primary, Gutierrez Diaz, Blanca, additional, Pieters, Tim, additional, Zhou, Yalu, additional, Narang, Sonali, additional, Fijalkwoski, Igor, additional, Borin, Cristina, additional, Van Laere, Jolien, additional, Payton, Monique, additional, Cho, Byoung-Kyu, additional, Han, Cuijuan, additional, Sun, Limin, additional, Serafin, Valentina, additional, Yacu, George, additional, Von Loocke, Wouter, additional, Basso, Giuseppe, additional, Veltri, Giulia, additional, Dreveny, Ingrid, additional, Ben-Sahra, Issam, additional, Goo, Young Ah, additional, Safgren, Stephanie L., additional, Tsai, Yi-Chien, additional, Bornhauser, Beat, additional, Suraneni, Praveen Kumar, additional, Gaspar-Maia, Alexandre, additional, Kandela, Irawati, additional, Van Vlierberghe, Pieter, additional, Crispino, John D., additional, Tsirigos, Aristotelis, additional, and Ntziachristos, Panagiotis, additional

Published
2022
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41. Data

Author

Mantis, Christine, Kandela, Irawati, and Aird, Fraser

Published
2022
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45. Study 19: Registered Report Additional Materials

Author

Kandela, Irawati, Jin, Hyun Yong, Owen, Katherine, Iorns, Elizabeth, Gunn, William, Tan, Fraser, Lomax, Joelle, Perfito, Nicole, and Errington, Timothy

Subjects
myeloma, Reproducibility Project: Cancer Biology, methodology, human, bromodomain inhibitor, targeted therapy, mouse
Published
2022
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47. Data

Author

Aird, Fraser, Kandela, Irawati, and Mantis, Christine

Published
2022
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49. Figures

Author

Mantis, Christine, Kandela, Irawati, Aird, Fraser, Iorns, Elizabeth, Denis, Alexandria, Williams, Stephen, Perfito, Nicole, and Errington, Timothy

Published
2022
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