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3. Comparison of early versus late addition of granulocyte and monocyte adsorption for incomplete remission induction in ulcerative colitis.

Author

Tominaga, Keiichi, Kanazawa, Mimari, Watanabe, Shoko, Tanaka, Takanao, Kojimahara, Shunsuke, Masuyama, Satoshi, Abe, Keiichiro, Kanamori, Akira, Yamamiya, Akira, Sugaya, Takeshi, Goda, Kenichi, Fujita, Yuji, Yoshihara, Shigemi, Haruyama, Yasuo, and Irisawa, Atsushi

Subjects
REMISSION induction, ULCERATIVE colitis, CALCINEURIN
Abstract

Background and aim: Ulcerative colitis (UC) is characterized by repeated relapse and remission. Because no fundamental therapeutic strategy has been established, the treatment goal is generally to maintain the remission phase for a long period after rapid remission induction. Granulocyte and monocyte adsorption (GMA) for UC is reportedly quite safe because it does not affect immunosuppression. Moreover, it is useful in combination with other remission induction therapy. The aim of this study was to evaluate the difference in efficacy by the timing of the addition of GMA with corticosteroids, calcineurin inhibitors, and anti‐cytokine therapy for active UC. Methods: The study included 59 patients. Patients who started GMA of 5–11 days were in the early GMA combination group. Patients who started GMA 12 days or more were in the late GMA combination group. The primary endpoint was difference in the effect of additional GMA according to the timing of the intervention. The secondary endpoint was difference in the time to remission induction between the two groups. Results: Of the 32 early GMA group patients, 24 achieved remission induction. Of the 27 late group patients, 18 achieved remission induction. No significant difference in induction rates was found (P = 0.481). The early group had shorter mean time to remission induction (P < 0.001). Conclusions: In conclusion, results suggest that early addition of GMA might lead to earlier remission in patients who have had an inadequate response to remission induction therapy with corticosteroids, calcineurin inhibitors, and anti‐cytokine therapy. [ABSTRACT FROM AUTHOR]

Published
2024
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6. Risk Factors for Developing Metachronous Superficial Gastric Epithelial Neoplasms after Endoscopic Submucosal Dissection.

Author

Suzuki, Tsunehiro, Goda, Kenichi, Ishikawa, Manabu, Yamaguchi, Shintaro, Yoshinaga, Tomonori, Kondo, Masayuki, Kanazawa, Mimari, Kunogi, Yasuhito, Tanaka, Takanao, Kanamori, Akira, Abe, Keiichiro, Yamamiya, Akira, Sugaya, Takeshi, Tominaga, Keiichi, Yamagishi, Hidetsugu, Masuyama, Hironori, and Irisawa, Atsushi

Subjects
HELICOBACTER pylori infections, GASTRIC mucosa, DUODENAL tumors, HELICOBACTER pylori, TUMORS, STOMACH cancer, DISSECTION
Abstract

Background: Although endoscopic submucosal dissection (ESD) provides a high rate of curative resection, the remaining gastric mucosa after ESD is at risk for metachronous superficial gastric epithelial neoplasms (MSGENs). It leaves room for risk factors for developing MSGENs after ESD. This study aimed to identify clinicopathological risk factors for the occurrence of MSGENs, and to evaluate the association of Helicobacter pylori (H. pylori) with the MSGENs. Methods: We conducted a retrospective cohort study including 369 patients with 382 lesions that underwent ESD for adenoma/early gastric cancer. Results: Twenty-seven MSGENs occurred. The subjects were divided into MSGEN and not-MSGEN groups. There was a significantly higher frequency of histological intestinal metaplasia (HIM) and initial neoplasm location in the upper or middle parts (INUM) in the MSGEN group. The HIM and INUM groups had a significantly higher cumulative incidence of MSGENs. We compared 27 patients from the MSGEN group and 27 patients from the not-MSGEN group that were matched to the MSGEN group for variables including HIM and INUM. There was a significantly higher frequency of the spontaneous disappearance of H. pylori in the MSGEN group. Conclusions: HIM, INUM, and the spontaneous disappearance of H. pylori may be clinicopathological risk factors for developing MSGENs after ESD. [ABSTRACT FROM AUTHOR]

Published
2024
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8. Advanced Endoscopy for Benign Esophageal Disease: A Review Focused on Non-Erosive Reflux Disease and Eosinophilic Esophagitis

Author

Goda, Kenichi, primary, Abe, Keiichiro, additional, Kanamori, Akira, additional, Kondo, Masayuki, additional, Kojimahara, Shunsuke, additional, Kanazawa, Mimari, additional, Tanaka, Takanao, additional, Nagashima, Kazunori, additional, Suzuki, Tsunehiro, additional, Yamamiya, Akira, additional, Hoshi, Koki, additional, Tominaga, Keiichi, additional, Majima, Yuichi, additional, Iijima, Makoto, additional, and Irisawa, Atsushi, additional

Published
2022
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11. Size reduction of gastric fundic gland polyposis by de‐escalation of acid‐suppressive therapy

Author

Kanamori, Akira, primary, Tominaga, Keiichi, additional, Masuyama, Hironori, additional, Ishikawa, Mutsumi, additional, Masuyama, Satoshi, additional, Kondo, Masayuki, additional, Kanazawa, Mimari, additional, Tanaka, Takanao, additional, Yamaura, Masamichi, additional, Abe, Keiichiro, additional, Watanabe, Shoko, additional, Yamamiya, Akira, additional, Abe, Yoko, additional, Goda, Kenichi, additional, and Irisawa, Atsushi, additional

Published
2022
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13. Curative resection with endoscopic submucosal dissection of early gastric cancer in Helicobacter pylori-negative Ménétrier’s disease: A case report

Author

Fukushi, Koh, primary, Goda, Kenichi, additional, Kino, Hitoshi, additional, Kondo, Masayuki, additional, Kanazawa, Mimari, additional, Kashima, Ken, additional, Kanamori, Akira, additional, Abe, Keiichiro, additional, Suzuki, Tsunehiro, additional, Tominaga, Keiichi, additional, Yamagishi, Hidetsugu, additional, and Irisawa, Atsushi, additional

Published
2022
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14. Making Hematochezia of Unknown Origin Known: A Retrospective Analysis

Author

Tanaka, Takanao, primary, Tominaga, Keiichi, additional, Yamamiya, Akira, additional, Sugaya, Takeshi, additional, Kanazawa, Mimari, additional, Kondo, Masayuki, additional, Abe, Keiichiro, additional, Kanamori, Akira, additional, Iijima, Makoto, additional, Goda, Kenichi, additional, Haruyama, Yasuo, additional, and Irisawa, Atsushi, additional

Published
2022
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15. Analysis of Endoscopic Evaluation Reliability for Ulcerative Colitis in Histological Remission

Author

Kanazawa, Mimari, primary, Tominaga, Keiichi, additional, Yamamiya, Akira, additional, Tanaka, Takanao, additional, Watanabe, Shoko, additional, Sugaya, Takeshi, additional, Abe, Keiichiro, additional, Kanamori, Akira, additional, Arisaka, Takahiro, additional, Hoshi, Koki, additional, Iijima, Makoto, additional, Goda, Kenichi, additional, Haruyama, Yasuo, additional, and Irisawa, Atsushi, additional

Published
2021
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16. A case of ileal ectopic pancreas required differentiation from GIST

Author

Watanabe, Shoko, primary, Kanazawa, Mimari, additional, Tanaka, Takanao, additional, Tominaga, Keiichi, additional, Kondo, Masayuki, additional, Kashima, Ken, additional, Kunogi, Yasuhito, additional, Abe, Keiichiro, additional, Kanamori, Akira, additional, Goda, Kenichi, additional, Ishida, Kazuyuki, additional, Takagi, Kazutoshi, additional, Kubota, Keiichi, additional, and Irisawa, Atsushi, additional

Published
2021
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17. A Case of Crohn’s Disease with Cardiac Tamponade Caused by Tuberculous Pericarditis: Assessment of a Rare Phenomenon

Author

Tominaga, Keiichi, primary, Tanaka, Takanao, additional, Kanazawa, Mimari, additional, Watanabe, Shoko, additional, Nemoto, Rena, additional, Abe, Keiichiro, additional, Kanamori, Akira, additional, Yamamiya, Akira, additional, Goda, Kenichi, additional, Kushima, Yoshitomo, additional, Chibana, Kazuyuki, additional, Masawa, Taito, additional, Fukuda, Tomohiro, additional, Hibi, Toshifumi, additional, and Irisawa, Atsushi, additional

Published
2021
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18. Refractory Immune Checkpoint Inhibitor-Induced Colitis Improved by Tacrolimus: A Case Report

Author

Kunogi, Yasuhito, primary, Tominaga, Keiichi, additional, Abe, Keiichiro, additional, Kanazawa, Mimari, additional, Tanaka, Takanao, additional, Watanabe, Shoko, additional, Kondo, Masayuki, additional, Kanamori, Akira, additional, Iijima, Makoto, additional, Goda, Kenichi, additional, Nozawa, Yumi, additional, Ishida, Kazuyuki, additional, and Irisawa, Atsushi, additional

Published
2021
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19. Factors Affecting Technical Difficulty in Balloon Enteroscopy-Assisted Endoscopic Retrograde Cholangiopancreatography in Patients with Surgically Altered Anatomy

Author

Izawa, Naoya, primary, Tsuchida, Kohei, additional, Tominaga, Keiichi, additional, Fukushi, Koh, additional, Sakuma, Fumi, additional, Kashima, Ken, additional, Kunogi, Yasuhito, additional, Kanazawa, Mimari, additional, Tanaka, Takanao, additional, Nagashima, Kazunori, additional, Minaguchi, Takahito, additional, Iwasaki, Mari, additional, Yamamiya, Akira, additional, Jinnai, Hidehito, additional, Yamabe, Akane, additional, Hoshi, Koki, additional, Sugaya, Takeshi, additional, Iijima, Makoto, additional, Goda, Kenichi, additional, and Irisawa, Atsushi, additional

Published
2021
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22. Gastric Dieulafoy’s lesion with subepithelial lesion-like morphology

Author

Tanaka, Takanao, primary, Sugaya, Takeshi, additional, Tominaga, Keiichi, additional, Kanazawa, Mimari, additional, Suzuki, Tsunehiro, additional, Ishikawa, Mutsumi, additional, Yamamiya, Akira, additional, Arisaka, Takahiro, additional, Majima, Yuichi, additional, Iijima, Makoto, additional, Goda, Kenichi, additional, and Irisawa, Atsushi, additional

Published
2020
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25. Multiple esophageal ulcers due to tofacitinib 10 mg twice daily for ulcerative colitis

Author

Tominaga, Keiichi, primary, Kanazawa, Mimari, additional, Takenaka, Kazuhiro, additional, Tanaka, Takanao, additional, Sugaya, Takeshi, additional, Fukushi, Koh, additional, Takagi, Yuka, additional, Nagashima, Kazunori, additional, Abe, Keiichiro, additional, Izawa, Naoya, additional, Tsuchida, Kohei, additional, Iijima, Makoto, additional, Goda, Kenichi, additional, Yamagishi, Hidetsugu, additional, and Irisawa, Atsushi, additional

Published
2019
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28. Relationship between endoscopic mucosal healing and histologic inflammation during remission maintenance phase in ulcerative colitis: a retrospective study

Author

Kanazawa, Mimari, additional, Takahashi, Fumiaki, additional, Tominaga, Keiichi, additional, Abe, Keiichiro, additional, Izawa, Naoya, additional, Fukushi, Koh, additional, Nagashima, Kazunori, additional, Kanamori, Akira, additional, Takenaka, Kazuhiro, additional, Sugaya, Takeshi, additional, Iijima, Makoto, additional, Takada, Atsuko, additional, Imai, Yasuo, additional, Hiraishi, Hideyuki, additional, and Irisawa, Atsushi, additional

Published
2019
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