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Your search keyword '"Kamikokuryo, Chinatsu"' showing total 16 results
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16 results on '"Kamikokuryo, Chinatsu"'

3. Comparative Study of Blood Neopterin and Biopterins in Patients with COVID-19 and Secondary Bacterial Infection.

Author

Eguchi, Tomohiro, Niiyama, Shuhei, Kamikokuryo, Chinatsu, Madokoro, Yutaro, Shimono, Kenshin, Hara, Satoshi, Ichinose, Hiroshi, and Kakihana, Yasuyuki

Subjects
COVID-19, BACTERIAL diseases, LYMPHOCYTE count, VIRUS diseases, ARTIFICIAL respiration
Abstract

Background/Objectives: As COVID-19 can be severe, early predictive markers of both severity and onset of secondary bacterial infections are needed. This study first examined changes over time in the levels of plasma neopterin (NP) and biopterins (BPs), among others, in patients with COVID-19 and then in those with secondary bacterial infection complications. Methods: Fifty-two patients with COVID-19 admitted to two tertiary care centers were included. They were divided into a severe group (intubated + mechanical ventilation) (n = 10) and a moderate group (non-intubated + oxygen administration) (n = 42), and changes over time in plasma NP, plasma BPs, IFN-γ, lymphocyte count, CRP, and IL-6 were investigated. Four of the patients in the severe group (n = 10) developed secondary bacterial infections during treatment. Plasma NP and plasma BPs of patients with bacterial sepsis (no viral infection) (n = 25) were also examined. Results: The plasma NP, IL-6, CRP, and SOFA levels were significantly higher in the severe group, while the IFN-γ level and lymphocyte count were significantly lower. The higher plasma NP in the severe group persisted only up to 1 week after symptom onset. The plasma BPs were higher in complications of bacterial infection. Conclusions: The timing of sample collection is important for assessing severity through plasma NP, while plasma BPs may be a useful diagnostic tool for identifying the development of secondary bacterial infection in patients with COVID-19. Further investigation is needed to clarify the mechanism by which NP and BPs, which are involved in the same biosynthetic pathway, are differentially activated depending on the type of pathogen. [ABSTRACT FROM AUTHOR]

Published
2024
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4. Monitoring of Brain Oxygenation During and After Cardiopulmonary Resuscitation: A Prospective Porcine Study

Author

Kakihana, Yasuyuki, Kamikokuryo, Chinatsu, Furubeppu, Hiroaki, Madokoro, Yutaro, Futatsuki, Takahiro, Miyamoto, Shotaro, Haraura, Hiroyuki, Hatanaka, Kousaku, Eguchi, Tomohiro, Saitoh, Yasuo, Miura, Naoki, Suzuki, Hiroaki, Ueda, Yukio, Yasuda, Tomotsugu, Ito, Takashi, COHEN, IRUN R., Editorial Board Member, LAJTHA, ABEL, Editorial Board Member, LAMBRIS, JOHN D., Editorial Board Member, PAOLETTI, RODOLFO, Editorial Board Member, REZAEI, NIMA, Editorial Board Member, Thews, Oliver, editor, LaManna, Joseph C., editor, and Harrison, David K., editor

Published
2018
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7. Uric acid enhances alteplase-mediated thrombolysis as an antioxidant

Author

Kikuchi, Kiyoshi, Setoyama, Kentaro, Tanaka, Eiichiro, Otsuka, Shotaro, Terashi, Takuto, Nakanishi, Kazuki, Takada, Seiya, Sakakima, Harutoshi, Ampawong, Sumate, Kawahara, Ko-ichi, Nagasato, Tomoka, Hosokawa, Kazuya, Harada, Yoichiro, Yamamoto, Mika, Kamikokuryo, Chinatsu, Kiyama, Ryoji, Morioka, Motohiro, Ito, Takashi, Maruyama, Ikuro, and Tancharoen, Salunya

Published
2018
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13. A multicenter non-randomized, uncontrolled single arm trial for evaluation of the efficacy and the safety of the treatment with favipiravir for patients with severe fever with thrombocytopenia syndrome

Author

Suemori, Koichiro, primary, Saijo, Masayuki, additional, Yamanaka, Atsushi, additional, Himeji, Daisuke, additional, Kawamura, Masafumi, additional, Haku, Takashi, additional, Hidaka, Michihiro, additional, Kamikokuryo, Chinatsu, additional, Kakihana, Yasuyuki, additional, Azuma, Taichi, additional, Takenaka, Katsuto, additional, Takahashi, Toru, additional, Furumoto, Akitsugu, additional, Ishimaru, Toshiyuki, additional, Ishida, Masayuki, additional, Kaneko, Masahiko, additional, Kadowaki, Norimitsu, additional, Ikeda, Kenichi, additional, Sakabe, Shigetoshi, additional, Taniguchi, Tomohiro, additional, Ohge, Hiroki, additional, Kurosu, Takeshi, additional, Yoshikawa, Tomoki, additional, Shimojima, Masayuki, additional, and Yasukawa, Masaki, additional

Published
2021
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14. Comparison of the Levels of Neopterin, CRP, and IL-6 in Patients Infected with and without SARS-CoV-2

Author

Hara, Satoshi, primary, Sanatani, Tama, additional, Tachikawa, Natsuo, additional, Yoshimura, Yukihiro, additional, Miyata, Nobuyuki, additional, Sasaki, Hiroaki, additional, Kuroda, Risa, additional, Kamikokuryo, Chinatsu, additional, Eguchi, Tomohiro, additional, Niiyama, Shuhei, additional, Kakihana, Yasuyuki, additional, and Ichinose, Hiroshi, additional

Published
2021
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16. Edaravone, a Synthetic Free Radical Scavenger, Enhances Alteplase-Mediated Thrombolysis

Author

Kikuchi, Kiyoshi, primary, Setoyama, Kentaro, additional, Kawahara, Ko-ichi, additional, Nagasato, Tomoka, additional, Terashi, Takuto, additional, Ueda, Koki, additional, Nakanishi, Kazuki, additional, Otsuka, Shotaro, additional, Miura, Naoki, additional, Sameshima, Hisayo, additional, Hosokawa, Kazuya, additional, Harada, Yoichiro, additional, Shrestha, Binita, additional, Yamamoto, Mika, additional, Morimoto-Yamashita, Yoko, additional, Kikuchi, Haruna, additional, Kiyama, Ryoji, additional, Kamikokuryo, Chinatsu, additional, Tancharoen, Salunya, additional, Sakakima, Harutoshi, additional, Morioka, Motohiro, additional, Tanaka, Eiichiro, additional, Ito, Takashi, additional, and Maruyama, Ikuro, additional

Published
2017
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