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231 results on '"Kamachi, Kazunari"'

4. Sero and Carriage Epidemiology of Pertussis in Urban and Rural Regions in Vietnam

Author

Toizumi, Michiko, primary, Le, Lien Thuy, additional, Nguyen, Hien Anh Thi, additional, Le, Thao Thi Thu, additional, Kitamura, Noriko, additional, Bui, Liem Xuan, additional, Ho, Nen Minh, additional, Do, Hung Thai, additional, Kamachi, Kazunari, additional, Otsuka, Nao, additional, Bui, Minh Xuan, additional, Dang, Duc Anh, additional, and Yoshida, Lay-Myint, additional

Published
2024
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6. Macrolide-Resistant Bordetella pertussis, Vietnam, 2016-2017

Author

Kamachi, Kazunari, Duong, Hong T., Dang, Anh D., Do, Hai T., Koide, Kentaro, Otsuka, Nao, Shibayama, Keigo, and Hoang, Ha Thi Thu

Subjects
Diseases, Analysis, International economic relations, Genetic aspects, Bordetella pertussis -- Analysis -- Genetic aspects, Communicable diseases -- Genetic aspects, RNA -- Analysis -- Genetic aspects
Abstract

Pertussis (whooping cough) is a highly contagious disease caused by the gram-negative bacterium Bordetella pertussis. Vaccination is an effective method to prevent and control pertussis, but in many countries, pertussis [...]

Published
2020
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8. Strain identity of Bordetella pertussis isolates from household members based on whole‐genome sequencing.

Author

Kamachi, Kazunari, Koide, Kentaro, Otsuka, Nao, Goto, Masataka, and Kenri, Tsuyoshi

Subjects
WHOLE genome sequencing, BORDETELLA pertussis, HOUSEHOLDS, SINGLE nucleotide polymorphisms, GENETIC variation, COMPARATIVE genomics, NUCLEOTIDE sequencing
Abstract

We evaluated the genetic diversity of Bordetella pertussis, the causative agent of pertussis, within households by whole‐genome sequencing. In pairwise comparisons of 23 isolates collected from 11 households, single‐nucleotide polymorphism (SNP) analysis revealed extremely low SNP diversity (≤1 SNP) between isolate pairs: no SNPs were detected in 10 households and one SNP was obtained in the remaining household. This SNP was uncommon for B. pertussis and resulted in a nonsynonymous substitution (Ala303Thr) in nicotinate phosphoribosyltransferase. We demonstrated that the same strain is transmitted between household members and that B. pertussis is genomically stable during household transmission. [ABSTRACT FROM AUTHOR]

Published
2024
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12. Significant decrease in pertactin-Deficient Bordetella pertussis isolates, Japan

Author

Hiramatsu, Yukihiro, Miyaji, Yusuke, Otsuka, Nao, Arakawa, Yoshichika, Shibayama, Keigo, and Kamachi, Kazunari

Subjects
Usage, Genetic aspects, Research, Vaccines -- Usage -- Research, Bordetella pertussis -- Genetic aspects -- Research
Abstract

Bordetella pertussis, a highly communicable, gram-negative coccobacillus, is the etiologic agent of pertussis (whooping cough), an acute respiratory infection that leads to severe illness in children. Vaccination is the most [...]

Published
2017
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20. Transmission of Bordetella holmesii during pertussis outbreak, Japan

Author

Kamiya, Hajime, Otsuka, Nao, Ando, Yuka, Odaira, Fumito, Yoshino, Shuji, Kawano, Kimiko, Takahashi, Hirokazu, Nishida, Toshihide, Hidaka, Yoshio, Toyoizumi-Ajisaka, Hiromi, Shibayama, Keigo, Kamachi, Kazunari, Sunagawa, Tomimasa, Taniguchi, Kiyosu, and Okabe, Nobuhiko

Subjects
Diagnosis, Research, Causes of, Health aspects, Disease transmission -- Research, Whooping cough -- Diagnosis -- Causes of, Epidemics -- Diagnosis -- Causes of -- Japan, Medical research, Bordetella -- Health aspects, Medicine, Experimental, Whooping-cough -- Diagnosis -- Causes of
Abstract

We describe the epidemiology of a pertussis outbreak in Japan in 2010-2011 and Bordetella holmesii transmission. Six patients were infected; 4 patients were students and a teacher at the same [...]

Published
2012
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23. Plasmid pBP136 from Bordetella pertussis represents an ancestral form of IncP-1[beta] plasmids without accessory mobile elements

Author

Kamachi, Kazunari, Sota, Masahiro, Tamai, Yuji, Nagata, Noriyo, Konda, Toshifumi, Inoue, Toshiro, Top, Eva M., and Arakawa, Yoshichika

Subjects
Bordetella pertussis -- Genetic aspects, Nucleotide sequence -- Research, Genetic research, Biological sciences
Abstract

The complete 41 268 bp nucleotide sequence of the IncP-1[beta] plasmid pBP136 from the human pathogen Bordetella pertussis, the primary aetiological agent of whooping cough, was determined and analysed. This plasmid carried a total of 46 ORFs: 44 ORFs corresponding to the genes in the conserved IncP-1[beta] backbone, and 2 ORFs similar to the XF1596 and XF1597 genes with unknown function of the plant pathogen Xylella fastidiosa. Interestingly, pBP136 had no accessory genes carrying genetic traits such as antibiotic or mercury resistance and/or xenobiotic degradation. Moreover, pBP136 had only two of the kle genes (kleAE) that have been reported to be important for the stability of IncP-1 plasmid in Pseudomonas aeruginosa. Phylogenetic analysis of the Kle proteins revealed that the KleA and KleE of pBP136 were phylogenetically distant from those of the present IncP-1 plasmids. In contrast, IncC1 and KorC, encoded upstream and downstream of the kle genes respectively, and the replication-initiation protein, TrfA, were closely related to those of the IncP-1[beta] 'R751 group'. These results suggest that (i) pBP136 without any apparent accessory genes diverged early from an ancestor of the present IncP-1[beta] plasmids, especially those of the R751 group, and (ii) the kle genes might be incorporated independently into the backbone region of the IncP-1 plasmids for their stable maintenance in various host cells. DOI 10.1099/mic.0.29056-0

Published
2006

24. Genotyping and macrolide-resistant mutation of Bordetella pertussisin East and South-East Asia

Author

Koide, Kentaro, Yao, ShuMan, Chiang, Chuen‑Sheue, Thuy, Phung Thi Bich, Nga, Do Thi Thuy, Huong, Do Thu, Dien, Tran Minh, Vichit, Ork, Vutthikol, Yong, Sovannara, Siphan, Samnang, Chham, Takayama, Ikuyo, Ainai, Akira, Nakajima, Noriko, Otsuka, Nao, Kamachi, Kazunari, and Saitoh, Akihiko

Abstract

•Molecular surveillance of macrolide-resistant Bordetella pertussis(MRBP) was performed in East and Southeast Asia.•MBRP was detected in Vietnam, Cambodia, Taiwan, and Japan.•Most MRBP had the same MT104 and MT195 genotypes as Chinese MRBP.•The first MRBP isolates from Taiwan belonged to the MT104 cluster of Chinese MRBP.

Published
2022
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40. Bordetella pertussis population dynamics and phylogeny in Japan after adoption of acellular pertussis vaccines

Author

LS Klinisch Onderzoek Wagenaar, dI&I I&I-4, Zomer, Aldert, Otsuka, Nao, Hiramatsu, Yukihiro, Kamachi, Kazunari, Nishimura, Naoko, Ozaki, Takao, Poolman, Jan Theunis, Geurtsen, Jeroen, LS Klinisch Onderzoek Wagenaar, dI&I I&I-4, Zomer, Aldert, Otsuka, Nao, Hiramatsu, Yukihiro, Kamachi, Kazunari, Nishimura, Naoko, Ozaki, Takao, Poolman, Jan Theunis, and Geurtsen, Jeroen

Published
2018

46. A Novel IgM-capture enzyme-linked immunosorbent assay using recombinant Vag8 fusion protein for the accurate and early diagnosis ofBordetella pertussisinfection

Author

Otsuka, Nao, primary, Gotoh, Kensei, additional, Nishimura, Naoko, additional, Ozaki, Takao, additional, Nakamura, Yukitsugu, additional, Haga, Kiyohito, additional, Yamazaki, Makoto, additional, Gondaira, Fumio, additional, Okada, Kenji, additional, Miyaji, Yusuke, additional, Toyoizumi-Ajisaka, Hiromi, additional, Shibayama, Keigo, additional, Arakawa, Yoshichika, additional, and Kamachi, Kazunari, additional

Published
2016
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47. Macrolide-Resistant Bordetella pertussis, Vietnam, 2016-2017.

Author

Kazunari Kamachi, Duong, Hong T., Dang, D., Do, Hai T., Kentaro Koide, Nao Otsuka, Keigo Shibayama, Ha Thi Thu Hoang, Kamachi, Kazunari, Dang, Anh D, Hai, T, Do, Do, Koide, Kentaro, Otsuka, Nao, Shibayama, Keigo, and Hoang, Ha Thi Thu

Abstract

Macrolide-resistant Bordetella pertussis emerged in Vietnam during 2016-2017. Direct analyses of swab samples from 10 patients with pertussis revealed a macrolide-resistant mutation, A2047G, in the 23S rRNA. We identified the MT104 genotype of macrolide-resistant B. pertussis (which is prevalent in mainland China) and its variants in these patients. [ABSTRACT FROM AUTHOR]

Published
2020
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50. Global Population Structure and Evolution of Bordetella pertussis and Their Relationship with Vaccination

Author

Bart, Marieke J., primary, Harris, Simon R., additional, Advani, Abdolreza, additional, Arakawa, Yoshichika, additional, Bottero, Daniela, additional, Bouchez, Valérie, additional, Cassiday, Pamela K., additional, Chiang, Chuen-Sheue, additional, Dalby, Tine, additional, Fry, Norman K., additional, Gaillard, María Emilia, additional, van Gent, Marjolein, additional, Guiso, Nicole, additional, Hallander, Hans O., additional, Harvill, Eric T., additional, He, Qiushui, additional, van der Heide, Han G. J., additional, Heuvelman, Kees, additional, Hozbor, Daniela F., additional, Kamachi, Kazunari, additional, Karataev, Gennady I., additional, Lan, Ruiting, additional, Lutyńska, Anna, additional, Maharjan, Ram P., additional, Mertsola, Jussi, additional, Miyamura, Tatsuo, additional, Octavia, Sophie, additional, Preston, Andrew, additional, Quail, Michael A., additional, Sintchenko, Vitali, additional, Stefanelli, Paola, additional, Tondella, M. Lucia, additional, Tsang, Raymond S. W., additional, Xu, Yinghua, additional, Yao, Shu-Man, additional, Zhang, Shumin, additional, Parkhill, Julian, additional, and Mooi, Frits R., additional

Published
2014
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