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4. Pulmonary function abnormalities are common in patients with multiple myeloma and are independently associated with worse outcome

Author

Trakada, Georgia, Kastritis, Efstathios, Gavriatopoulou, Maria, Velentza, Lemonia, Fotiou, Despina, Ziogas, Dimitrios C., Panagiotidis, Ioannis, Eleutherakis-Papaiakovou, Evangelos, Roussou, Maria, Migkou, Magdalini, Kanellias, Nikolaos, Ntanasis-Stathopoulos, Ioannis, Kallianos, Anastasios, Terpos, Evangelos, and Dimopoulos, Meletios A.

Published
2019
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6. Small airways dysfunction in patients with systemic sclerosis and interstitial lung disease

Author

Panagopoulos, Panagiotis K., primary, Goules, Andreas V., additional, Georgakopoulou, Vasiliki E., additional, Kallianos, Anastasios, additional, Chatzinikita, Eirini, additional, Pezoulas, Vasileios C., additional, Malagari, Katerina, additional, Fotiadis, Dimitrios I., additional, Vlachoyiannopoulos, Panayiotis, additional, Vassilakopoulos, Theodoros, additional, and Tzioufas, Athanasios G., additional

Published
2022
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7. Pulmonary function tests reveal unrecognised lung dysfunction and have independent prognostic significance in patients with systemic AL amyloidosis

Author

Trakada, Georgia, primary, Fotiou, Despina, additional, Kallianos, Anastasios, additional, Theodorakakou, Foteini, additional, Migkou, Magdalini, additional, Gavriatopoulou, Maria, additional, Kanellias, Nikolaos, additional, Malandrakis, Panagiotis, additional, Ntanasis-Stathopoulos, Ioannis, additional, Eleutherakis-Papaiakovou, Evangelos, additional, Dialoupi, Ioanna, additional, Terpos, Evangelos, additional, Dimopoulos, Meletios A., additional, and Kastritis, Efstathios, additional

Published
2022
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9. Cardiopulmonary Exercise Physiology in AL Amyloidosis Patients with Cardiac Involvement and Its Association with Cardiac Imaging Parameters

Author

Briasoulis, Alexandros, primary, Theodorakakou, Foteini, additional, Rempakos, Athanasios, additional, Petropoulos, Ioannis, additional, Gavriatopoulou, Maria, additional, Androulakis, Emmanuel, additional, Stamatelopoulos, Kimon, additional, Kallianos, Anastasios, additional, Trakada, Georgia, additional, Dimopoulos, Meletios Athanasios, additional, and Kastritis, Efstathios, additional

Published
2022
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10. “Peculiar” Snoring in a 40-Year-Old Patient: A Case Report and Review of Literature

Author

Economou, Nicholas-Tiberio, Cholidou, Kyriaki, Kallianos, Anastasios, Weiss, Katja; https://orcid.org/0000-0003-1247-6754, Knechtle, Beat; https://orcid.org/0000-0002-2412-9103, Nikolaidis, Pantelis T; https://orcid.org/0000-0001-8030-7122, Trakada, Georgia; https://orcid.org/0000-0003-0037-1269, Economou, Nicholas-Tiberio, Cholidou, Kyriaki, Kallianos, Anastasios, Weiss, Katja; https://orcid.org/0000-0003-1247-6754, Knechtle, Beat; https://orcid.org/0000-0002-2412-9103, Nikolaidis, Pantelis T; https://orcid.org/0000-0001-8030-7122, and Trakada, Georgia; https://orcid.org/0000-0003-0037-1269

Abstract

This is a case description of a patient with previously diagnosed rapid eye movement sleep behavior disorder (RBD) and nocturnal enuresis, who complained about a "peculiar sound" while sleeping and, occasionally, while awake during intensive exercise, for the last three months. A home audio recording, which his wife obtained while he was sleeping, showed a high-pitched sound identified as stridor. Full video polysomnography revealed no apneas or hypopneas. The flow-volume loop yielded an inspiratory plateau, indicating variable extrathoracic obstruction. The upper and lower respiratory system computed tomography did not show any anomalies or mechanical lesions (e.g., masses and scars). Fiberoptic laryngoscopy revealed an abnormal activity of the vocal cord abductor during quiet breathing and inspiration in a supine position, leading to partial obstruction. A positive dopamine transporter scan and the coexistence of stridor, RBD, and nocturnal enuresis were diagnostic for multiple system atrophy. The patient was treated with continuous positive airway pressure as a symptomatic therapy for stridor and levodopa. Keywords: dopamine transporter scan; nocturnal enuresis; rapid eye movement sleep behavior disorder; sleep; stridor.

Published
2022

11. Pulmonary function tests reveal unrecognised lung dysfunction and have independent prognostic significance in patients with systemic AL amyloidosis.

Author

Trakada, Georgia, Fotiou, Despina, Kallianos, Anastasios, Theodorakakou, Foteini, Migkou, Magdalini, Gavriatopoulou, Maria, Kanellias, Nikolaos, Malandrakis, Panagiotis, Ntanasis-Stathopoulos, Ioannis, Eleutherakis-Papaiakovou, Evangelos, Dialoupi, Ioanna, Terpos, Evangelos, Dimopoulos, Meletios A., and Kastritis, Efstathios

Subjects
PULMONARY function tests, VITAL capacity (Respiration), AMYLOIDOSIS, RESPIRATORY muscles, COMPUTED tomography
Abstract

Lung involvement in AL amyloidosis is not very common, but post-mortem data and retrospective studies suggest it is likely underrecognized. To perform a comprehensive evaluation of lung function with pulmonary function tests (PFTs) in patients with newly diagnosed AL amyloidosis. A prospective, non-interventional study of 139 consecutive patients with newly diagnosed AL amyloidosis. PFTs indicated normal breathing physiology in 68% of patients, obstructive in 9% and restrictive in 23%; the latter was associated with worse survival (28.6 vs 76 months for obstructive/normal physiology, p = 0.002) and remained significant after adjustment for Mayo stage and abnormal chest-CT. Forced vital capacity <80% of predicted value, forced expiratory volume <80% of predicted value, and carbon monoxide diffusion capacity <70% were independently associated with poorer survival. Respiratory muscle strength (as assessed by maximal expiratory (Pe) and inspiratory (Pi) pressure) was affected in most patients (64% had Pi < 55% and 57% had Pe < 70% of predicted values). Pe% was an independent prognostic factor for survival (HR: 0.984 per 1% unit increase, p = 0.007). Pulmonary dysfunction, as assessed with PFTs, is common and underrecognized in patients with systemic AL amyloidosis, with significant prognostic and potentially therapeutic implications, independent of the degree of cardiac dysfunction or chest-CT findings. [ABSTRACT FROM AUTHOR]

Published
2023
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13. Visceral leishmaniasis and COVID-19 coinfection - A case report

Author

Pikoulas, Antonis Piperaki, Evangelia-Theophano Spanakos, Gregory Kallianos, Anastasios Mparmparousi, Despoina and Rentziou, Gianna Trakada, Georgia

Abstract

As the COVID-19 pandemic spreads across the globe, it will undoubtedly cross paths with long endemic infectious diseases in different areas. Interactions between SARS-CoV2 and well-known pathogens will likely give rise to unfamiliar clinical presentations, depending on complex and as yet unknown immunological interactions. We present a case of coinfection with COVI19 and visceral leishmaniasis and discuss recent reports regarding coexistence of SARS-CoV2 and Leishmania spp. to date. (C) 2021 Published by Elsevier Ltd.

Published
2022

16. Hellenic registry of patients with home mechanical ventilation (HR-HMV): profiling sleep Apnea-Hypopnea syndrome patients across Greece.

Author

Dimitriadis, Vlasios K., Alexopoulou, Christina, Amfilochiou, Anastasia, Steiropoulos, Paschalis, Trakada, Georgia, Siopi, Dimitra, Pataka, Athanasia, Hatziagorou, Elpis, Konstandinidis, Athanasios, HR-HMV Data Curation Group, Varsou, Georgia, Chasiotou, Anastasia, Kallianos, Anastasios, Gounidis, Athanasios, Kondili, Eumorfia, Tselepi, Charikleia, Chasapidou, Georgia, Voulgaris, Athanasios, George, Kalamaras, and Chrysochou, Elissavet-Anna

Abstract

Background: Chronic respiratory conditions are a prominent public health issue and thus, building a patient registry might facilitate both policy decision making and improvement of clinical management processes. Hellenic Registry of patients with Home Mechanical Ventilation (HR-HMV) was initiated in 2017 and a web-based platform is used to support patient data collection. Eighteen hospital departments (including sleep labs) across Greece participate in this initiative, focusing on recording data for both children and adult patients supported by mechanical ventilation at home, including patients with Sleep Apnea-Hypopnea Syndrome (SAHS) under Positive Airway Pressure (PAP) therapy.Methods: The HR-HMV initiative ultimately aims to provide a database for evidence-based care and policy making in this specific domain. To this end, a web information system was developed and data were manually collected by clinics and hospital departments. Legal and privacy issues (such as General Data Protection Rule compliance and technical information security measures) have been considered while designing the web application. Based on the collected data, an exploratory statistical report of SAHS patients in Greece is presented.Results: Eleven out of the eighteen participating clinics and hospital departments have contributed with data by the time of the current study. More than 5000 adult and children patient records have been collected so far, the vast majority of which (i.e., 4900 patients) diagnosed with SAHS.Conclusion: The development and maintenance of patient registries is a valuable tool for policy decision making, observational/epidemiological research and beyond (e.g., health technology assessment procedures). However, as all data collection and processing approaches, registries are also related with potential biases. Along these lines, strengths and limitations must be considered when interpreting the collected data, and continuous validation of the collected clinical data per se should be emphasized. Especially for Greece, where the lack of national registries is eminent, we argue that HR-HMV could be a useful tool for the development and the update of related policies regarding the healthcare services for patients with home mechanical ventilation support and SAHS patients, which could be useful for related initiatives at a European level as well. [ABSTRACT FROM AUTHOR]

Published
2022
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17. Elevated pulmonary arterial systolic pressure in patients with sarcoidosis: prevalence and risk factors

Author

Rapti, Aggeliki, Kouranos, Vasileios, Gialafos, Elias, Aggeli, Konstantina, Moyssakis, John, Kallianos, Anastasios, Kostopoulos, Charalampos, Anagnostopoulou, Ourania, Sfikakis, Petros P., Wells, Athol U., and Tzelepis, George E.

Subjects
Doppler echocardiography -- Usage -- Health aspects, Pulmonary hypertension -- Risk factors -- Research, Sarcoidosis -- Risk factors -- Diagnosis -- Care and treatment, Health
Abstract

Background Sarcoidosis-related pulmonary hypertension (SRPH) is an entity associated with significant morbidity and mortality irrespective of disease severity, while the pathogenic mechanisms remain poorly understood. Methods This cross-sectional study included consecutive patients with biopsy-proven sarcoidosis (n = 313) who were followed up in an outpatient setting from October 2002 through June 2010. All patients underwent clinical and cardiopulmonary evaluation, including cardiac MRI, to assess prevalence of SRPH and identify possible underlying pathophysiological mechanisms. Results By Doppler echocardiography criteria, 37 (11.8%) patients were found to have pulmonary arterial systolic pressure (PASP) >40 mmHg. Twelve of the 37 patients agreed to undergo right heart catheterization and SRPH was confirmed in nine patients. Compared to patients without SRPH, those with SRPH were significantly older and had greater lung function impairment; disease duration did not differ between patients with and without SRPH. Multiple logistic regression analysis showed that diffusing capacity for carbon monoxide (DLCO) and age were independent determinants of SRPH. Pulmonary fibrosis and left ventricular diastolic dysfunction due to cardiac sarcoidosis or other comorbidities accounted for SRPH in the majority of patients. In the nonpulmonary fibrosis group, DLCO [less than or equal to] 50.65 (% predicted) was associated with SRPH (sensitivity = 77.8%, specificity = 72.2%; p = 0.031, AUC = 0.759). Conclusion In a large cohort of sarcoidosis patients, this study found a prevalence of SRPH of about 12%. Pulmonary fibrosis and left ventricular diastolic dysfunction due to cardiac sarcoidosis or other comorbidities are frequent pathogenic mechanisms. Keywords Sarcoidosis * Pulmonary arterial systolic pressure * Diastolic dysfunction, Introduction Sarcoidosis is a systemic granulomatous disease of unknown etiology characterized by variable clinical manifestations [1]. Sarcoidosis-related pulmonary hypertension (SRPH), initially considered a rare complication of advanced disease, is now [...]

Published
2013
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18. Prevalence of Cardiometabolic Disease in the Greek Sleep Apnea Patients Cohort

Author

Trakada, Georgia, primary, Dimitriadis, Vlasios, additional, Amfilochiou, Anastasia, additional, Siopi, Dimitra, additional, Paschidou, Vasiliki, additional, Alexopoulou, Christina, additional, Varsou, Georgia, additional, Konstantinidis, Athanasios, additional, Steiropoulos, Paschalis, additional, Pataka, Athanasia, additional, Karachristos, Christos, additional, Agrafiotis, Michalis, additional, Chasiotou, Anastasia, additional, Tselepi, Charikleia, additional, Kallianos, Anastasios, additional, Fountoulaki, Maria, additional, Gounidis, Athanasios, additional, Porpodis, Konstantinos, additional, Kondili, Eumorfia, additional, Natsiavas, Pantelis, additional, and Tsara, Venetia, additional

Published
2021
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22. A Pilot Study About the Dysfunction of Adipose Tissue in Male, Sleep Apneic Patients in Relation to Psychological Symptoms

Author

Trakada, Georgia Nikolaidis, Pantelis T. Economou, Nicholas-Tiberio Sakkas, Dimitrios Giagkou, Giorgos and Sakellariou, Stratigoula Kyriakopoulou, Konstantina Patsouris, Efstratios Ferini-Strambi, Luigi Velentza, Lemonia and Kallianos, Anastasios Rosemann, Thomas Knechtle, Beat and Mitrakou, Asimina

Abstract

Introduction: Obstructive sleep apnea (OSA) and its cardiometabolic alterations are closely associated with visceral obesity. Patients with OSA frequently present with symptoms of depression and anxiety. Although these subjective symptoms of OSA are the result of complex biological dysregulation, it remains unclear if they have a direct effect on the dysfunction of adipose tissue. Methods: In a pilot, prospective, randomized study, we evaluated 10 recently diagnosed male patients with severe OSA by full polysomnography (PSG) and 4 male non-apneic subjects matched for age and body mass index (BMI) with abdomen adipose tissue biopsies. Subjects with diabetes/prediabetes and cardiovascular and psychiatric diseases and who are current smokers were excluded. All patients underwent anthropometric measurements and completed the following questionnaires: Epworth Sleepiness Scale (ESS), Fatigue Severity Scale (FSS), and Hospital Anxiety and Depression Scale (HADS-A and HADS-D). Fasting venous blood samples were collected on the day after PSG, between 8:00 and 9:00 a.m., after an overnight fast. Fat biopsies were performed at the same time periods and adipose tissue samples of 300 mg were obtained from abdominal fat. Fat cell size, extent of fibrosis, vascularity, leukocyte common antigen inflammatory infiltration, and tissue macrophage accumulation were microscopically evaluated. Results: The mean age of the group was 47.4 +/- 13.8 years, with mean BMI of 35.8 +/- 4.8 kg/m(2) and mean apnea-hypopnea index of 79.4 +/- 46.1 events per hour of sleep (severe OSA). HADS-A and HADS-D scores were 5.8 +/- 2.3 (3.0-8.0) and 4.7 +/- 2.3 (2.0-8.0), respectively. HADS-A score correlated positively with macrophage accumulation in fat biopsy (r = 0.82, p = 0.047), whereas ESS, FSS, and HADS-D did not. Severity of fibrosis correlated largely with waist circumference (r = -0.66, p = 0.038) and neck circumference (r = -0.790, p = 0.006). Respiratory events correlated negatively with the extent of vascularization of adipose tissue (r = -0.614, p = 0.05). Conclusions: In the preliminary results of our pilot study, we assessed that the symptoms of anxiety mainly contribute to macrophage accumulation, whereas the increased number of respiratory events reduces the extent of vascularization in visceral fat in OSA. Based on this observation, further larger studies are required to verify if anxious OSA patients are more vulnerable to the metabolic manifestations of the syndrome.

Published
2019

23. A Pilot Study About the Dysfunction of Adipose Tissue in Male, Sleep Apneic Patients in Relation to Psychological Symptoms

Author

Trakada, Georgia, Nikolaidis, Pantelis T, Economou, Nicholas-Tiberio, Sakkas, Dimitrios, Giagkou, Giorgos, Sakellariou, Stratigoula, Kyriakopoulou, Konstantina, Patsouris, Efstratios, Ferini-Strambi, Luigi, Velentza, Lemonia, Kallianos, Anastasios, Rosemann, Thomas; https://orcid.org/0000-0002-6436-6306, Knechtle, Beat; https://orcid.org/0000-0002-2412-9103, Mitrakou, Asimina, Trakada, Georgia, Nikolaidis, Pantelis T, Economou, Nicholas-Tiberio, Sakkas, Dimitrios, Giagkou, Giorgos, Sakellariou, Stratigoula, Kyriakopoulou, Konstantina, Patsouris, Efstratios, Ferini-Strambi, Luigi, Velentza, Lemonia, Kallianos, Anastasios, Rosemann, Thomas; https://orcid.org/0000-0002-6436-6306, Knechtle, Beat; https://orcid.org/0000-0002-2412-9103, and Mitrakou, Asimina

Published
2019

24. Clinical Characteristics of Obstructive Sleep Apnea in Psychiatric Disease

Author

Knechtle, Beat; https://orcid.org/0000-0002-2412-9103, Economou, Nicholas-Tiberio, Nikolaidis, Pantelis T; https://orcid.org/0000-0001-8030-7122, Velentza, Lemonia, Kallianos, Anastasios, Steiropoulos, Paschalis, Koutsompolis, Dimitrios, Rosemann, Thomas; https://orcid.org/0000-0002-6436-6306, Trakada, Georgia; https://orcid.org/0000-0003-0037-1269, Knechtle, Beat; https://orcid.org/0000-0002-2412-9103, Economou, Nicholas-Tiberio, Nikolaidis, Pantelis T; https://orcid.org/0000-0001-8030-7122, Velentza, Lemonia, Kallianos, Anastasios, Steiropoulos, Paschalis, Koutsompolis, Dimitrios, Rosemann, Thomas; https://orcid.org/0000-0002-6436-6306, and Trakada, Georgia; https://orcid.org/0000-0003-0037-1269

Abstract

Patients with serious psychiatric diseases (major depressive disorder (MDD), bipolar disorder (BD), and schizophrenia and psychotic disorder) often complain about sleepiness during the day, fatigue, low energy, concentration problems, and insomnia; unfortunately, many of these symptoms are also frequent in patients with Obstructive Sleep Apnea (OSA). However, existing data about the clinical appearance of OSA in Psychiatric Disease are generally missing. The aim of our study was a detailed and focused evaluation of OSA in Psychiatric Disease, in terms of symptoms, comorbidities, clinical characteristics, daytime respiratory function, and overnight polysomnography data. We examined 110 patients (56 males and 54 females) with stable Psychiatric Disease (Group A: 66 with MDD, Group B: 34 with BD, and Group C: 10 with schizophrenia). At baseline, each patient answered the STOP-Bang Questionnaire, Epworth Sleepiness Scale (ESS), Fatigue Severity Scale (FSS), and Hospital Anxiety and Depression Scale (HADS) and underwent clinical examination, oximetry, spirometry, and overnight polysomnography. Body Mass Index (BMI), neck, waist, and hip circumferences, and arterial blood pressure values were also measured. The mean age of the whole population was 55.1 ± 10.6 years. The three groups had no statistically significant difference in age, BMI, hip circumference, and systolic and diastolic arterial blood pressure. Class II and III obesity with BMI > 35 kg/m was observed in 36 subjects (32.14%). A moderate main effect of psychiatric disease was observed in neck ( = 0.044, = 0.064) and waist circumference ( = 0.021, = 0.078), with the depression group showing the lowest values, and in pulmonary function (Forced Vital Capacity (FVC, %), = 0.013, = 0.084), with the psychotic group showing the lowest values. Intermediate to high risk of OSA was present in 87.37% of participants, according to the STOP-Bang Questionnaire (≥3 positive answers), and 70.87% responded positively for feeli

Published
2019

25. A Pilot Study About the Dysfunction of Adipose Tissue in Male, Sleep Apneic Patients in Relation to Psychological Symptoms

Author

Trakada, Georgia, primary, Nikolaidis, Pantelis T., additional, Economou, Nicholas-Tiberio, additional, Sakkas, Dimitrios, additional, Giagkou, Giorgos, additional, Sakellariou, Stratigoula, additional, Kyriakopoulou, Konstantina, additional, Patsouris, Efstratios, additional, Ferini-Strambi, Luigi, additional, Velentza, Lemonia, additional, Kallianos, Anastasios, additional, Rosemann, Thomas, additional, Knechtle, Beat, additional, and Mitrakou, Asimina, additional

Published
2019
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27. Inhaled immunotherapy for lung cancer? Certainly possible

Author

Zarogoulidis, Pavlos, primary, Tsiouda, Dora, additional, Kallianos, Anastasios, additional, Rapti, Aggeliki, additional, Sardeli, Chrysanthi, additional, Huang, Haidong, additional, Hohenforst-Schmidt, Wolfgang, additional, Trakada, Georgia, additional, and Sapalidis, Konstantinos, additional

Published
2018
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29. Successful treatment of postoperative massive pulmonary embolism with paradoxal arterial embolism through extracorporeal life support and thrombolysis

Author

Grapatsas, Konstantinos, primary, Leivaditis, Vasileios, additional, Zarogoulidis, Paul, additional, Tsilogianni, Zoi, additional, Kotoulas, Sotirios, additional, Kotoulas, Christophoros, additional, Koletsis, Efstratios, additional, Iliadis, Ilias Stylianos, additional, Spiliotopoulos, Konstantinos, additional, Trakada, Georgia, additional, Veletza, Lemonia, additional, Kallianos, Anastasios, additional, Tsiouda, Theodora, additional, Kosmidis, Christoforos, additional, Hohenforst-Schmidt, Wolfgang, additional, Huang, Haidong, additional, Haussmann, Rainer, additional, Haussmann, Erich, additional, and Dahm, Manfred, additional

Published
2018
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30. Convex-probe endobronchial ultrasound for thyroid biopsy a new hybrid method

Author

Sapalidis, Konstantinos, primary, Kosmidis, Christoforos, additional, Laskou, Stella, additional, Zarogoulidis, Paul, additional, Karapantzos, Ilias, additional, Karapantzou, Chrysa, additional, Kallianos, Anastasios, additional, Hohenforst-Schmidt, Wolfgang, additional, Karanikas, Michael, additional, Thomaidis, Vasilis, additional, Huang, Haidong, additional, Bai, Chong, additional, and Kesisoglou, Isaak, additional

Published
2018
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31. Hamman's syndrome (spontaneous pneumomediastinum presenting as subcutaneous emphysema): A rare case of the emergency department and review of the literature

Author

Grapatsas, Konstantinos, primary, Tsilogianni, Zoi, additional, Leivaditis, Vasileios, additional, Kotoulas, Sotirios, additional, Kotoulas, Christoforos, additional, Koletsis, Efstratios, additional, Iliadis, Ilias Stylianos, additional, Dahm, Manfred, additional, Trakada, Georgia, additional, Veletza, Lemonia, additional, Kallianos, Anastasios, additional, Huang, Haidong, additional, Kosmidis, Christoforos, additional, Karanikas, Michael, additional, Thomaidis, Vasilis, additional, Porpodis, Konstantinos, additional, and Zarogoulidis, Paul, additional

Published
2018
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35. Possible adverse effects of immunotherapy in non-small cell lung cancer; treatment and follow-up of three cases

Author

Zarogoulidis, Paul, primary, Chinelis, Panos, additional, Athanasiadou, Anastasia, additional, Tsiouda, Theodora, additional, Trakada, Georgia, additional, Kallianos, Anastasios, additional, Veletza, Lemonia, additional, Hatzibougias, Dimitris, additional, Mihalopoulou, Electra, additional, Goupou, Eirini, additional, Kosmidis, Christoforos, additional, Sardeli, Chrysanthi, additional, Huang, Haidong, additional, and Hohenforst-Schmidt, Wolfgang, additional

Published
2017
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36. Immunotherapy “Shock” a case series of PD-L1 100% and pembrolizumab first-line treatment

Author

Zarogoulidis, Paul, primary, Athanasiou, Evaggelia, additional, Tsiouda, Theodora, additional, Hatzibougias, Dimitrios, additional, Huang, Haidong, additional, Bai, Chong, additional, Trakada, Georgia, additional, Veletza, Lemonia, additional, Kallianos, Anastasios, additional, Kosmidis, Christoforos, additional, Barbetakis, Nikolaos, additional, Paliouras, Dimitrios, additional, Rapti, Aggeliki, additional, Drougas, Dimitrios, additional, and Hohenforst-Schmidt, Wolfgang, additional

Published
2017
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37. Progressive dyspnea due to pulmonary carcinoid tumorlets

Author

Kallianos, Anastasios, primary, Velentza, Lemonia, additional, Zarogoulidis, Paul, additional, Baka, Sofia, additional, Kosmidis, Christoforos, additional, Labaki, Sofia, additional, Lazaridis, George, additional, Huang, Haidong, additional, Hohenforst-Schmidt, Wolfgang, additional, and Trakada, Georgia, additional

Published
2017
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38. Endobronchial ultrasound convex probe for lymphoma, sarcoidosis, lung cancer and other thoracic entities. A case series

Author

Zarogoulidis, Paul, primary, Huang, Haidong, additional, Bai, Chong, additional, Kosmidis, Christoforos, additional, Trakada, Georgia, additional, Veletza, Lemonia, additional, Tsiouda, Theodora, additional, Barbetakis, Nikolaos, additional, Paliouras, Dimitrios, additional, Athanasiou, Evangelia, additional, Hatzibougias, Dimitris, additional, Kallianos, Anastasios, additional, Panagiotopoulos, Nikolaos, additional, Papaemmanouil, Liana, additional, and Hohenforst-Schmidt, Wolfgang, additional

Published
2017
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39. Immunotherapy “Shock” with vitiligo due to nivolumab administration as third line therapy in lung adenocarcinoma

Author

Zarogoulidis, Paul, primary, Huang, Haidong, additional, Tsiouda, Theodora, additional, Sardeli, Chrysa, additional, Trakada, Georgia, additional, Veletza, Lemonia, additional, Kallianos, Anastasios, additional, Kosmidis, Christoforos, additional, Rapti, Aggeliki, additional, Papaemmanouil, Liana, additional, Hatzibougias, Dimitrios, additional, Drougas, Dimitrios, additional, Bai, Chong, additional, and Hohenforst-Schmidt, Wolfgang, additional

Published
2017
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40. EGFR or PD-L1 decision for first line therapy in a case series of EGFR positive and PD-L1 >50%

Author

Zarogoulidis, Paul, primary, Chinelis, Panos, additional, Efthymiou, Christofors, additional, Athanasiadou, Anastasia, additional, Mpikos, Vasilis, additional, Papatsibas, George, additional, Papadopoulos, Vasilis, additional, Maragouli, Elena, additional, Huang, Haidong, additional, Trakada, Georgia, additional, Kallianos, Anastasios, additional, Veletza, Lemonia, additional, and Hohenforst-Schmidt, Wolfgang, additional

Published
2017
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41. “Liquid elbows” due to afatinib administration

Author

Zarogoulidis, Paul, primary, Chinelis, Panos, additional, Athanasiadou, Anastasia, additional, Porpodis, Konstantinos, additional, Kallianos, Anastasios, additional, Rapti, Aggeliki, additional, Trakada, Georgia, additional, Velentza, Lemonia, additional, Huang, Haidong, additional, Tsiouda, Theodora, additional, and Hohenforst-Schmidt, Wolfgang, additional

Published
2017
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43. Re-biopsy after relapse of targeted therapy. T790M after epidermal growth factor mutation, where and why based on a case series

Author

Zarogoulidis, Paul, primary, Rapti, Aggeliki, additional, Sardeli, Chrysanthi, additional, Chinelis, Panagiotis, additional, Athanasiadou, Anastasia, additional, Paraskevaidou, Katerina, additional, Kallianos, Anastasios, additional, Veletza, Lemonia, additional, Trakada, Georgia, additional, Hohenforst-Schmidt, Wolfgang, additional, and Huang, Haidong, additional

Published
2017
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46. Sex differences of continuous positive airway pressure treatment on flow-mediated dilation in patients with obstructive sleep apnea syndrome

Author

Kallianos, Anastasios Panoutsopoulos, Athanasios Mermigkis, Christoforos Kostopoulos, Konstantinos Papamichail, Chrysanthi and Kokkonouzis, Ioannis Kostopoulos, Christoforos Nikolopoulos, Ioannis Papaiwannou, Antonis Lampaki, Sofia Organtzis, John and Pitsiou, Georgia Zarogoulidis, Paul Trakada, Georgia

Subjects
respiratory tract diseases
Abstract

Introduction: There is growing research evidence suggesting the presence of endothelial dysfunction and systemic inflammation in patients with obstructive sleep apnea syndrome (OSAS). Continuous positive airway pressure (CPAP) is the most effective method for treating OSAS; nonetheless, the effects of CPAP on the aforementioned pathophysiologic pathways as well as on the systemic disease that result or coexist with the OSAS remain elusive. Aim: To assess the effect of 3-month CPAP therapy on endothelial-dependent dilation, plasma levels of inflammatory markers, blood pressure (BP), and glucose control on male and female patients with OSAS. Methods: Our study group consisted of 40 (24 males and 16 females) patients with no prior history of cardiovascular disease, with an apnea-hypopnea index >= 15, who were assigned to receive CPAP treatment. Measurements of flow-mediated dilation (FMD), 24-hour ambulatory BP, and blood analysis were performed at baseline and 3 months after CPAP therapy. Results: Baseline FMD values were negatively correlated with the apnea-hypopnea index (r=-0.55, P=0.001). After 3 months of CPAP, there was an increase in the FMD values (5.40%+/- 2.91% vs 3.13%+/- 3.15%, P

Published
2015

47. AB056. Outcomes of pulmonary rehabilitation in COPD patients-correlation with stage of the disease, symptoms, history of exacerbations and cardiovascular comorbidity

Author

Kallianos, Anastasios, primary, Charikiopoulou, Maria, additional, Velentza, Lemonia, additional, Andrianopoulos, Alexandros, additional, Bekas, Evaggelos, additional, Kokolios, Aggelos, additional, Rekliti, Elena, additional, Dadoudi, Basiliki, additional, Trakada, Georgia, additional, and Rapti, Aggeliki, additional

Published
2016
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