Author: "Kalani, H." - Searchworks@Jio Institute Digital Library Search Results

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1. High‐Efficiency Multilevel Phase Lenses with Nanostructures on Polyimide Membranes.

Author: Howe, Leslie, Rajapaksha, Tharindu D., Ellepola, Kalani H., Ho, Vinh X., Aycock, Zachary, Nguyen, Minh L. P., Leckey, John P., Macdonnell, Dave G., Kim, Hyun Jung, and Vinh, Nguyen Q.
Subjects: NANOSTRUCTURES, INSTRUMENT flying, SPACE flight, REMOTE sensing, NANOFABRICATION, ULTRAFILTRATION, DIFFRACTIVE scattering, LENSES
Abstract: The emergence of planar meta‐lenses on flexible materials has profoundly impacted the long‐standing perception of diffractive optics. Despite their advantages, these lenses still face challenges in design and fabrication to obtain high focusing efficiency and resolving power. A nanofabrication technique is demonstrated based on photolithography and polyimide casting for realizing membrane‐based multilevel phase‐type Fresnel zone plates (FZPs) with high focusing efficiency. By employing advantageous techniques, these lenses with nanostructures are directly patterned into thin polyimide membranes. The computational and experimental results have indicated that the focusing efficiency of these nanostructures at the primary focus increases significantly with increasing the number of phase levels. Specifically, 16‐level phase lenses on a polyimide membrane can achieve a focusing efficiency of more than 91.6% of the input signal (9.5 times better than that of a conventional amplitude‐type FZP) and focus light into a diffraction‐limited spot together with very weak side‐lobes. Furthermore, these lenses exhibit considerably reduced unwanted diffraction orders and produce extremely low background signals. The potential impact of these lenses extends across various applications and techniques including microscopy, imaging, micro‐diffraction, remote sensing, and space flight instruments which require lightweight and flexible configurations. [ABSTRACT FROM AUTHOR]
Published: 2024
Full Text: View/download PDF

2. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019

Author: Abbafati, C., Machado, D.B., Cislaghi, B., Salman, O.M., Karanikolos, M., McKee, M., Abbas, K.M., Brady, O.J., Larson, H.J., Trias-Llimós, S., Cummins, S., Langan, S.M., Sartorius, B., Hafiz, A., Jenabi, E., Mohammad Gholi Mezerji, N., Borzouei, S., Azarian, G., Khazaei, S., Abbasi, M., Asghari, B., Masoumi, S., Komaki, H., Taherkhani, A., Adabi, M., Abbasifard, M., Bazmandegan, G., Kamiab, Z., Vakilian, A., Anjomshoa, M., Mokari, A., Sabour, S., Shahbaz, M., Saeedi, R., Ahmadieh, H., Yousefinezhadi, T., Haj-Mirzaian, A., Nikbakhsh, R., Safi, S., Asgari, S., Irvani, S.N., Jahanmehr, N., Ramezanzadeh, K., Abbasi-Kangevari, M., Khayamzadeh, M., Abbastabar, H., Shirkoohi, R., Fazlzadeh, M., Janjani, H., Hosseini, M., Mansournia, M., Tohidinik, H., Bakhtiari, A., Fazaeli, A., Mousavi, S., Hasanzadeh, A., Nabavizadeh, B., Malekzadeh, R., Hashemian, M., Pourshams, A., Salimzadeh, H., Sepanlou, S.G., Afarideh, M., Esteghamati, A., Esteghamati, S., Ghajar, A., Heidari, B., Rezaei, N., Mohamadi, E., Rahimi-Movaghar, A., Rahim, F., Eskandarieh, S., Sahraian, M., Mohebi, F., Aminorroaya, A., Ebrahimi, H., Farzadfar, F., Mohajer, B., Pishgar, F., Saeedi Moghaddam, S., Shabani, M., Zarafshan, H., Abolhassani, H., Hafezi-Nejad, N., Heidari-Soureshjani, R., Abdollahi, M., Farahmand, M., Salamati, P., Mehrabi Nasab, E., Tajdini, M., Aghamir, S., Mirzaei, R., Dibaji Forooshani, Z., Khater, M.M., Abd-Allah, F., Abdelalim, A., Abualhasan, A., El-Jaafary, S.I., Hassan, A., Elsharkawy, A., Khater, A.M., Elhabashy, H.R., Salem, M.R.R., Salem, H., Sadeghi, M., Jafarinia, M., Amini-Rarani, M., Mohammadifard, N., Sarrafzadegan, N., Abdollahpour, I., Sarveazad, A., Tehrani-Banihashemi, A., Yoosefi Lebni, J., Manafi, N., Pazoki Toroudi, H., Dorostkar, F., Alipour, V., Sheikhtaheri, A., Arabloo, J., Azari, S., Ghashghaee, A., Rezapour, A., Naserbakht, M., Kabir, A., Mehri, F., Yousefifard, M., Asadi-Aliabadi, M., Babaee, E., Eshrati, B., Goharinezhad, S., Moradi-Lakeh, M., Abedi, P., Rashedi, V., Kumar, V., Elgendy, I.Y., Basu, S., Park, J., Pereira, A., Norheim, O.F., Eagan, A.W., Cahill, L.E., Sheikh, A., Abushouk, A.I., Kraemer, M.U.G., Thakur, B., Bärnighausen, T.W., Shrime, M.G., Abedi, A., Doshi, C.P., Abegaz, K.H., Geberemariyam, B.S., Aynalem, Y.A., Shiferaw, W.S., Abosetugn, A.E., Aboyans, V., Abrams, E.M., Gitimoghaddam, M., Kissoon, N., Stubbs, J.L., Brauer, M., Iyamu, I.O., Kopec, J.A., Pourmalek, F., Ribeiro, A.P., Malta, D.C., Gomez, R.S., Abreu, L.G., Abrigo, M.R.M., Almulhim, A.M., Dahlawi, S.M.A., Pottoo, F.H., Menezes, R.G., Alanzi, T.M., Alumran, A.K., Abu Haimed, A.K., Madadin, M., Alanezi, F.M., Abu-Gharbieh, E., Saddik, B., Abu-Raddad, L.J., Samy, A.M., El Nahas, N., Shalash, A.S., Nabhan, A.F., Kamath, A.M., Kassebaum, N.J., Aravkin, A.Y., Kochhar, S., Sorensen, R.J.D., Afshin, A., Burkart, K., Cromwell, E.A., Dandona, L., Dharmaratne, S.D., Gakidou, E., Hay, S.I., Kyu, H.H., Lopez, A.D., Lozano, R., Misganaw, A.T., Mokdad, A.H., Naghavi, M., Pigott, D.M., Reiner Jr, R.C., Roth, G.A., Stanaway, J.D., Vollset, S., Vos, T., Wang, H., Lim, S.S., Murray, C.J.L., Kalani, R., Ikuta, K.S., Cho, D.Y., Kneib, C.J., Crowe, C.S., Massenburg, B.B., Morrison, S.D., Acebedo, A., Adelson, J.D., Agesa, K.M., Alam, T., Albertson, S.B., Anderson, J.A., Antony, C.M., Ashbaugh, C., Assmus, M., Azhar, G., Balassyano, S., Bannick, M.S., Barthelemy, C.M., Bender, R.G., Bennitt, F.B., Bertolacci, G.J., Biehl, M.H., Bisignano, C., Boon-Dooley, A.S., Briant, P.S., Bryazka, D., Bumgarner, B.R., Callender, C.S., Cao, J., Castle, C.D., Castro, E., Causey, K., Cercy, K.M., Chalek, J., Charlson, F.J., Cohen, A.J., Comfort, H., Compton, K., Croneberger, A.J., Cruz, J.A., Cunningham, M., Dandona, R., Dangel, W.J., Dean, F.E., DeCleene, N.K., Deen, A., Degenhardt, L., Dingels, Z.V., Dippenaar, I.N., Dirac, M.A., Dolgert, A.J., Emmons-Bell, S., Estep, K., Farag, T., Feigin, V.L., Feldman, R., Ferrara, G., Ferrari, A.J., Fitzgerald, R., Force, L.M., Fox, J.T., Frank, T.D., Fu, W., Fukutaki, K., Fuller, J.E., Fullman, N., Galles, N.C., Gardner, W.M., Gershberg Hayoon, A., Goren, E., Gorman, T.M., Gottlich, H.C., Guo, G., Haddock, B., Hagins, H., Haile, L.M., Hamilton, E.B., Han, C., Han, H., Harvey, J.D., Henny, K., Henrikson, H.J., Henry, N.J., Herbert, M.E., Hsiao, T., Huynh, C.K., Iannucci, V.C., Ippolito, H., Irvine, C.M.S., Jafari, H., Jahagirdar, D., James, S.L., Johnson, C.O., Johnson, S.C., Keller, C., Kemmer, L., Kendrick, P.J., Knight, M., Kocarnik, J.M., Krohn, K.J., Larson, S.L., Lau, K.M., Ledesma, J.R., Leever, A.T., LeGrand, K.E., Lescinsky, H., Lin, C., Liu, H., Liu, Z., Lo, J., Lu, A., Ma, J., Maddison, E.R., Manguerra, H., Marks, A., Martopullo, I., Mastrogiacomo, C.I., May, E.A., Mooney, M.D., Mosser, J.F., Mullany, E.C., Mumford, J., Munro, S.B., Nandakumar, V., Nguyen, J., Nguyen, M., Nichols, E., Nixon, M.R., Odell, C.M., Ong, K.L., Orji, A.U., Ostroff, S.M., Pasovic, M., Paulson, K.R., Pease, S.A., Pennini, A., Pierce, M., Pilz, T.M., Pletcher, M., Rao, P.C., Razo, C., Redford, S.B., Reinig, N., Reitsma, M.B., Rhinehart, P., Robalik, T., Roberts, S., Roberts, N.L.S., Rolfe, S., Sbarra, A.N., Schaeffer, L.E., Shackelford, K.A., Shadid, J., Sharara, F., Shaw, D.H., Sheena, B.S., Simpson, K.E., Smith, A., Spencer, C.N., Spurlock, E.E., Stark, B.A., Steiner, C., Steuben, K.M., Sylte, D.O., Tang, M., Taylor, H.J., Terrason, S., Thomson, A.M., Torre, A.E., Travillian, R., Troeger, C.E., Vongpradith, A., Walters, M.K., Wang, J., Watson, A., Watson, S., Whisnant, J.L., Whiteford, H.A., Wiens, K.E., Wilner, L.B., Wilson, S., Wool, E.E., Wozniak, S.S., Wu, J., Wulf Hanson, S., Wunrow, H., Xu, R., Yadgir, S., Yearwood, J.A., York, H.W., Yuan, C., Zhao, J.T., Zheng, P., Zimsen, S.R.M., Zlavog, B.S., Chang, A.Y., Oren, E., Buchbinder, R., Chin, K.L., Guo, Y., Polkinghorne, K.R., Thrift, A.G., Lee, S.W.H., Ackerman, I.N., Cicuttini, F.M., Li, S., Zaman, S., Suleria, H., Zhang, J., Cowie, B.C., Wijeratne, T., Patton, G.C., Sawyer, S.M., Adair, T., Meretoja, A., Adetokunboh, O.O., Adamu, A.A., Iwu, C.J., Parry, C.D.H., Seedat, S., Ndwandwe, D.E., Mahasha, P.W., Stein, D.J., Nnaji, C.A., Sambala, E.Z., Wiysonge, C.S., Adebayo, O.M., Ilesanmi, O.S., Owolabi, M.O., Adeoye, A.M., Adedeji, I.A., Adekanmbi, V., Ibitoye, S.E., John-Akinola, Y.O., Oluwasanu, M.M., Oghenetega, O.B., Akinyemi, R.O., Zandian, H., Adham, D., Zahirian Moghadam, T., Advani, S.M., Teagle, W.L., Braithwaite, D., Agasthi, P., Saadatagah, S., Afshari, M., Agardh, E.E., Allebeck, P., Danielsson, A., Deuba, K., Carrero, J.J., Mohammad, D.K., Fereshtehnejad, S., Ärnlöv, J., Nowak, C., Cederroth, C.R., Ahmadi, A., Pathak, A., Mills, E.J., Kurmi, O.P., Olagunju, A.T., Agarwal, G., Sathish, T., Aghaali, M., Mohammadbeigi, A., Agrawal, A., Ahmad, T., Ahmadi, K., Maleki, S., Naderi, M., Salahshoor, M.R., Pourmirza Kalhori, R., Almasi, A., Salimi, Y., Siabani, S., Ziapour, A., Barzegar, A., Khazaie, H., Kianipour, N., Amiri, F., Salehi Zahabi, S., Mirzaei, M., Shamsi, M., Najafi, F., Jalali, A., Ghadiri, K., Heydarpour, F., Fattahi, N., Karami Matin, B., Kazemi Karyani, A., Pirsaheb, M., Rajati, F., Sadeghi, E., Safari, Y., Sharafi, K., Soltani, S., Vasseghian, Y., Atafar, Z., Jalilian, F., Mirzaei-Alavijeh, M., Saeidi, S., Soofi, M., Zangeneh, A., Mansouri, B., Ahmadi, M., Khafaie, M.A., Safiri, S., Moghadaszadeh, M., Asghari Jafarabadi, M., Doshmangir, L., Jadidi-Niaragh, F., Ghafourifard, M., Spotin, A., Khodayari, M., Samadi Kafil, H., Kalankesh, L.R., Ahmadpour, E., Yousefi, B., Ansari, F., Hassankhani, H., Karimi, S., Haririan, H., Mereta, S., Ahmed, M.B., Feyissa, G.T., Ciobanu, L.G., Aji, B., Aynalem, G.L., Gebresillassie, B., Tefera, Y.G., Akalu, T.Y., Baraki, A.G., Tesema, G.A., Tessema, Z.T., Tamiru, A.T., Azene, Z.N., Netsere, H.B., Yano, Y., Akinyemiju, T., Wu, C., Zadey, S., Samad, Z., Ji, J.S., Doshi, P.P., John, O., Jha, V., Maulik, P.K., Pesudovs, K., Resnikoff, S., Mitchell, P.B., Sachdev, P.S., Akombi, B., Godinho, M.A., Ivers, R.Q., Peden, A.E., Biswas, R., Boufous, S., Akunna, C.J., Alahdab, F., Hammer, M.S., van Donkelaar, A., Al-Aly, Z., Dellavalle, R.P., Alam, S., Martin, R.V., Alam, N., De Leo, D., Tadakamadla, S.K., Alam, K., Alcalde-Rabanal, J.E., Avila-Burgos, L., Serván-Mori, E., Denova-Gutiérrez, E., Rodríguez-Ramírez, S., Morales, L., Poznańska, A., Wojtyniak, B., Rivera, J.A., Campos-Nonato, I.R., Campuzano Rincon, J., Sánchez-Pimienta, T.G., Mengesha, M.B., Welay, F.T., Alema, N.M., Demsie, D.G., Teame, H., Teklehaimanot, B.F., Alemu, B.W., Gultie, T., Bante, A.B., Yeshitila, Y.G., Geramo, Y.C.D., Glagn, M., Sorrie, M.B., W/hawariat, F.G., Amare, A., Kasa, A., Alemu, Y., Mihretie, K.M., Atnafu, D.D., Demeke, F.M., Melese, A., Bante, S.A., Dessie, G.A., Mengesha, E.W., Nigatu, D., Almadi, M.A.H., Alhabib, K.F., Mohammad, Y., Altirkawi, K.A., Temsah, M., Kugbey, N., Ayanore, M.A., Alhassan, R.K., Ali, M., Ali, S., Alicandro, G., Kalhor, R., Alijanzadeh, M., Alinia, C., Yusefzadeh, H., Didarloo, A., Alizade, H., Nikpoor, A., Aljunid, S.M., Alla, F., Leal, L.F., Almasi-Hashiani, A., Moradzadeh, R., Zamanian, M., Nazari, J., Amini, S., Ghamari, F., Almasri, N.A., Khan, M., Al-Mekhlafi, H.M., Bedi, N., Alonso, J., Ciber, E.S.P., Al-Raddadi, R.M., Zakzuk, J., Alvis-Guzman, N., Alvis-Zakzuk, N.J., Castañeda-Orjuela, C.A., Malagón-Rojas, J.N., Gezae, K., Gesesew, H.A., Muthupandian, S., Gebremeskel, G.G., Berhe, K., Amare, B., Ayza, M.A., Gebremeskel, L.G., Gebreslassie, A.A.A., Bitew, H., Zewdie, K.A., Tela, F.G.G., Gill, T.K., Noubiap, J., Lassi, Z.S., Bhandari, D., Amit, A.L., Antonio, C.T., Faraon, E.A., Lopez, J.F., Atre, S.R., Ballew, S.H., Matsushita, K., Khoja, A.T., Daneshpajouhnejad, P., Ghadimi, M., Shafaat, O., Fanzo, J., Amugsi, D.A., Amul, G.H., Koh, D.S.Q., Venketasubramanian, N., Anbesu, E.W., Mohammed, J.A., Wondmeneh, T.G., Andrei, C., Negoi, R.I., Davitoiu, D.V., Manda, A., Negoi, I., Preotescu, L., Hostiuc, M., Hostiuc, S., Ancuceanu, R., Hasan, M., Leung, J., Anderlini, D., Mamun, A.A., Maravilla, J.C., McGrath, J.J., Lalloo, R., Uddin, R., Erskine, H.E., Knibbs, L.D., Mantilla Herrera, A.M., Santomauro, D.F., Mirica, A., Ausloos, M., Herteliu, C., Oţoiu, A., Pana, A., Andrei, T., Ştefan, S., Androudi, S., Angus, C., Ansari, I., Pourjafar, H., Shams-Beyranvand, M., Ansari-Moghaddam, A., Khammarnia, M., Antonazzo, I., Ferrara, P., Conti, S., Cortesi, P.A., Fornari, C., Lee, P.H., Antriyandarti, E., Yousefi, Z., Rafiei, A., Javidnia, J., Faridnia, R., Anvari, D., Goudarzian, A., Moosazadeh, M., Rezai, M., Daryani, A., Fareed, M., Anwer, R., Appiah, S., Paudel, D., Dichgans, M., Riahi, S., Rajabpour-Sanati, A., Arab-Zozani, M., Arba, A.A.K., Aremu, O., Ariani, F., Aripov, T., Armoon, B., Mahdavi, M.M., Arowosegbe, O.O., Tediosi, F., Aryal, K.K., Mosapour, A., Yaminfirooz, M., Arzani, A., Bijani, A., Jahani, M.A., Mouodi, S., Zamani, M., Asaad, M., Dianatinasab, M., Bahrami, M., Pakshir, K., Asadi-Pooya, A.A., Bayati, M., Shahabi, S., Athari, S., Atout, M.M.W., Atteraya, M.S., Brugha, T., Ausloos, F., Avokpaho, E.F.G., Room, R., Islam, M., Edvardsson, D., Rahman, M., Ayala Quintanilla, B., Gething, P.W., Briggs, A.M., Ayano, G., Hendrie, D., Miller, T.R., Azzopardi, P.S., Hoogar, P., B, D.B., Kulkarni, V., Kumar, N., Mithra, P., Shetty, R.S., Thapar, R., Padubidri, J., Bakkannavar, S.M., Nayak, V.C., Rastogi, P., Shetty, B.K., Bhageerathy, R., Gudi, N., Boloor, A., Holla, R., Rathi, P., Unnikrishnan, B., Janodia, M.D., Lang, J.J., Badawi, A., Orpana, H.M., Bhutta, Z.A., Shield, K.D., Chattu, V., Badiye, A.D., Kapoor, N., Bagherzadeh, M., Rabiee, N., Bagli, E., Baig, A.A., Bairwa, M., Lodha, R., Sagar, R., Rath, G.K., Bhardwaj, P., Charan, J., Kanchan, T., Joshi, A., Pakhare, A.P., Bakhshaei, M., Naghshtabrizi, B., Balachandran, A., Hoek, H.W., Postma, M.J., Geremew, A., Gebrehiwot, A.M., Balakrishnan, S., Desalew, A., Bojia, H.A., Mohammed, A.S., Regassa, L.D., Parmar, P.G.K., Balalla, S., Baldasseroni, A., Stokes, M.A., Ball, K., Islam, S., Maddison, R., Balzi, D., Levi, M., Banach, M., Banerjee, S.K., Banik, P.C., Barua, L., Faruque, M., Barboza, M.A., Barker-Collo, S.L., Jonas, J.B., Panda-Jonas, S., De Neve, J., Kohler, S., Moazen, B., Mohammed, S., Barrero, L.H., Basaleem, H., Bassat, Q., Haro, J.M., Koyanagi, A., Car, J., Greaves, F., Majeed, A., Davis, A.C., Steiner, T.J., Kusuma, D., Palladino, R., Rawaf, S., Saxena, S., Rawaf, D.L., Baune, B.T., Karch, A., Baye, B.A., Darega Gela, J., Kolola, T., Becker, J.S., DeLang, M., West, J., Gad, M.M., Serre, M.L., Gallus, S., Lugo, A., Beghi, E., Pupillo, E., Bosetti, C., Giussani, G., Bikbov, B., Perico, N., Remuzzi, G., Imani-Nasab, M., Nouraei Motlagh, S., Sharafi, Z., Behzadifar, M., Béjot, Y., Bekuma, T.T., Yilma, M.T., Bell, M.L., Bello, A.K., Rafiee, A., Keddie, S.H., Lucas, T.C.D., Dolecek, C., Dunachie, S.J., Rumisha, S.F., Weiss, D.J., Lewington, S., Collins, E.L., Nandi, A.K., Zhao, Y., Bennett, D.A., Karim, M.A., Lacey, B., Khundkar, R., Yaya, S., Goulart, A.C., Santos, I.S., Bensenor, I.M., Lotufo, P.A., Tovani-Palone, M.R., Castaldelli-Maia, J., Wang, Y., Furtado, J.M., Benziger, C.P., Berman, A.E., Mazidi, M., Bernabe, E., Dargan, P.I., Molokhia, M., Shibuya, K., Douiri, A., Wolfe, C.D.A., Hay, R.J., Flohr, C., Suchdev, P.S., Ram, P., Bernstein, R.S., Liu, Y., Bhagavathula, A.S., Khan, G., Grivna, M., Bhala, N., Chandan, J.S., Gaidhane, A.M., Quazi Syed, Z., Saxena, D., Khatib, M., Bhat, A.G., Bhattacharyya, K., Bhattarai, S., Das, J.K., Bibi, S., Bilano, V., Bin Sayeed, M., Cherbuin, N., D'Amico, E., Grosso, G., Borzì, A.M., Biondi, A., Vacante, M., Valli, A., Birihane, B.M., Bisanzio, D., Hassan, S., Bjørge, T., Øverland, S., Bockarie, M.J., Mensah, G.A., Sliwa, K., Gholamian, A., Bohlouli, S., Esmaeilnejad, S., Bohluli, M., Bolla, S.R., Borges, G., Bose, D., Bourne, R., Brayne, C., Breitborde, N.J.K., Fisher, J.L., Breitner, S., Brenner, H., Breusov, A.V., Rakovac, I., Briko, N.I., Lopukhov, P.D., Glushkova, E.V., Korshunov, V.A., Polibin, R.V., Jakovljevic, M., Briko, A.N., Britton, G.B., Castro, F., Moreno Velásquez, I., Burnett, R.T., Burugina Nagaraja, S., Busse, R., Butt, Z.A., Caetano dos Santos, F., Cai, T., Hall, B.J., Cahuana Hurtado, Lucero, Cámera, L.A., Valdez, P.R., Tudor Car, L., Cárdenas, R., Gorini, G., Carreras, G., Fernandes, E., Freitas, M., Pereira, D.M., Santos, J.V., Ribeiro, D., Pinheiro, M., Massano, J., das Neves, J., Dias da Silva, D., Carvalho, F., Costa, V.M., Silva, J.P., Morgado-da-Costa, J., Castelpietra, G., Catalá-López, F., Pakhale, S., Cerin, E., Yip, P., Ho, H., Chang, J., Chang, A.R., Chang, K., Cooper, O.R., Chaturvedi, S., Chimed-Ochir, O., Chirinos-Caceres, J.L., Choi, J.J., Christensen, H., Truelsen, T.C., Chu, D., Kivimäki, M., Chung, S., Kumar, M., Ward, J.L., Chung, M.T., Cirillo, M., Virclo, R., Classen, T.K.D., Lauriola, P., Corso, B., Hugo, F.N., Kieling, C., Cousin, E., Duncan, B.B., Goulart, B.N.G., Schmidt, M.I., Stein, C., Cowden, R.G., MacLachlan, J.H., Leigh, J., Cross, M., Ferreira, M.L., Smith, E.U.R., Driscoll, T.R., Huda, T.M., Hoy, D.G., Horita, N., Cross, D.H., Dai, H., Hu, G., Damasceno, A.A.M., Damiani, G., La Vecchia, C., Sanabria, J., Pandey, A., Mathur, M.R., Zodpey, S., Kumar, G., Lal, D.K., Hamagharib Abdullah, K., Hosseinzadeh, M., Darwesh, A.M., Faraj, A., Omar Bali, A., Das Gupta, R., Dash, A.P., Davey, G., Deribe, K., Gebremedhin, K.B., Wondmieneh, A.B., Dereje, N.D., Dávila-Cervantes, C.A., Davletov, K., Mereke, A., Serdar, B., Haile, T.G., Tadesse, D.B., Weldesamuel, G.T., Demoz, G.T., Woldu, G., Handiso, D., Dervenis, N., Topouzis, F., Desai, R., Dhungana, G.P., Emamian, M., Diaz, D., Djalalinia, S., Nguyen, T.H., Vu, G.T., Do, H.T., Dokova, K., Doku, D.T., Neupane, S., Takala, J.S., Doxey, M.C., Doyle, K.E., Renzaho, A.M.N., Ogbo, F.A., Robinson, S.R., Vukovic, A., Ilic, I.M., Santric-Milicevic, M.M., Vujcic, I.S., Dubljanin, E., Vukovic, R., Rasella, D., Duraes, 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Vlassov, V, Vollset, Se, Vos, T, Vujcic, I, Vukovic, A, Vukovic, R, Waheed, Y, Wallin, Mt, Walters, Mk, Wang, Hb, Wang, Yp, Watson, S, Wei, Jk, Weiss, J, Weldesamuel, Gt, Werdecker, A, Westerman, R, Whiteford, Ha, Wiangkham, T, Wiens, Ke, Wijeratne, T, Wiysonge, C, Wojtyniak, B, Wolfe, Cda, Wondmieneh, Ab, Wool, Ee, Wu, Am, Wu, Jj, Xu, Gl, Yamada, T, Yamagishi, K, Yano, Y, Yaya, S, Yazdi-Feyzabadi, V, Yearwood, Ja, Yeheyis, Ty, Yilgwan, C, Yip, P, Yonemoto, N, Yoon, Sj, Lebni, Jy, York, Hw, Younis, Mz, Younker, Tp, Yousefi, Z, Yousefinezhadi, T, Yousuf, Ay, Yusefzadeh, H, Moghadam, Tz, Zakzuk, J, Bin Zaman, S, Zamani, M, Zamanian, M, Zandian, H, Zhang, Zj, Zheng, P, Zhou, Mg, Ziapour, A, Murray, Cjl, Wang, Haidong, Abbas, Kaja M, Abbasifard, Mitra, Abbasi-Kangevari, Mohsen, Abbastabar, Hedayat, Abd-Allah, Foad, Abdelalim, Ahmed, Abolhassani, Hassan, Abreu, Lucas Guimarãe, Abrigo, Michael R M, Abushouk, Abdelrahman I, Adabi, Maryam, Adair, Tim, Adebayo, Oladimeji M, Adedeji, Isaac Akinkunmi, Adekanmbi, Victor, Adeoye, Abiodun Moshood, Adetokunboh, Olatunji O, Advani, Shailesh M, Afshin, Ashkan, Aghaali, Mohammad, Agrawal, Anurag, Ahmadi, Keivan, Ahmadieh, Hamid, Ahmed, Muktar Beshir, Al-Aly, Ziyad, Alam, Khurshid, Alam, Tahiya, Alanezi, Fahad Mashhour, Alanzi, Turki M, Alcalde-Rabanal, Jacqueline Elizabeth, Ali, Muhammad, Alicandro, Gianfranco, Alijanzadeh, Mehran, Alinia, Cyru, Alipour, Vahid, Alizade, Hesam, Aljunid, Syed Mohamed, Allebeck, Peter, Almadi, Majid Abdulrahman Hamad, Almasi-Hashiani, Amir, Al-Mekhlafi, Hesham M, Altirkawi, Khalid A, Alumran, Arwa Khalid, Alvis-Guzman, Nelson, Amini-Rarani, Mostafa, Aminorroaya, Arya, Amit, Arianna Maever L, Ancuceanu, Robert, Andrei, Catalina Liliana, Androudi, Sofia, Angus, Colin, Anjomshoa, Mina, Ansari, Fereshteh, Ansari, Iman, Ansari-Moghaddam, Alireza, Antonio, Carl Abelardo T, Antony, Catherine M, Anvari, Davood, Appiah, Seth Christopher Yaw, Arabloo, Jalal, Arab-Zozani, Morteza, Aravkin, Aleksandr Y, Aremu, Olatunde, Ärnlöv, Johan, Aryal, Krishna K, Asadi-Pooya, Ali A, Asgari, Samaneh, Asghari Jafarabadi, Mohammad, Atteraya, Madhu Sudhan, Ausloos, Marcel, Avila-Burgos, Leticia, Avokpaho, Euripide Frinel Gbenato Arthur, Ayala Quintanilla, Beatriz Paulina, Ayano, Getinet, Ayanore, Martin Amogre, Azarian, Ghasem, Babaee, Ebrahim, Badiye, Ashish D, Bagli, Eleni, Bahrami, Mohammad Amin, Bakhtiari, Ahad, Balassyano, Shelly, Banach, Maciej, Banik, Palash Chandra, Barker-Collo, Suzanne Lyn, Bärnighausen, Till Winfried, Barzegar, Akbar, Basu, Sanjay, Baune, Bernhard T, Bayati, Mohsen, Bazmandegan, Gholamreza, Bedi, Neeraj, Bell, Michellr L, Bennett, Derrick A, Bensenor, Isabela M, Berhe, Kidanemaryam, Berman, Adam E, Bertolacci, Gregory J, Bhageerathy, Reshmi, Bhala, Neeraj, Bhattacharyya, Krittika, Bhutta, Zulfiqar A, Bijani, Ali, Biondi, Antonio, Bisanzio, Donal, Bisignano, Catherine, Biswas, Raaj Kishore, Bjørge, Tone, Bohlouli, Somayeh, Bohluli, Mehdi, Bolla, Srinivasa Rao Rao, Borzì, Antonio Maria, Borzouei, Shiva, Brady, Oliver J, Braithwaite, Dejana, Brauer, Michael, Briko, Andrey Nikolaevich, Briko, Nikolay Ivanovich, Bumgarner, Blair R, Burugina Nagaraja, Sharath, Butt, Zahid A, Caetano dos Santos, Florentino Luciano, Cai, Tianji, Callender, Charlton SKH, Cámera, Luis LA Alberto, Campos-Nonato, Ismael R, Cárdenas, Rosario, Carreras, Giulia, Carrero, Juan J, Carvalho, Felix, Castaldelli-Maia, Joao Mauricio, Castelpietra, Giulio, Castro, Franz, Catalá-López, Ferrán, Cederroth, Christopher R, Cerin, Ester, Chattu, Vijay Kumar, Chin, Ken Lee, Chu, Dinh-Toi, Ciobanu, Liliana G, Cirillo, Massimo, Comfort, Haley, Costa, Vera Marisa, Cowden, Richard G, Cromwell, Elizabeth A, Croneberger, Andrew J, Cunningham, Matthew, Dahlawi, Saad M A, Damiani, Giovanni, D'Amico, Emanuele, Dandona, Lalit, Dandona, Rakhi, Dargan, Paul I, Darwesh, Aso Mohammad, Daryani, Ahmad, Das Gupta, Rajat, das Neves, José, Davletov, Kairat, De Leo, Diego, Denova-Gutiérrez, Edgar, Deribe, Kebede, Dervenis, Nikolao, Desai, Rupak, Dhungana, Govinda Prasad, Dias da Silva, Diana, Diaz, Daniel, Dippenaar, Ilse N, Djalalinia, Shirin, Do, Hoa Thi, Dokova, Klara, Doku, David Teye, Dorostkar, Fariba, Doshi, Chirag P, Doshmangir, Leila, Doyle, Kerrie E, Dubljanin, Eleonora, Duraes, Andre Rodrigue, Edvardsson, David, Effiong, Andem, El Sayed, Iman, El Tantawi, Maha, Elbarazi, Iffat, El-Jaafary, Shaimaa I, Emamian, Mohammad Hassan, Eskandarieh, Sharareh, Esmaeilzadeh, Firooz, Estep, Kara, Farahmand, Mohammad, Faraj, Anwar, Fareed, Mohammad, Faridnia, Roghiyeh, Faro, Andre, Farzadfar, Farshad, Fattahi, Nazir, Fazaeli, Ali Akbar, Fazlzadeh, Mehdi, Feigin, Valery L, Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Ferreira, Manuela L, Filip, Irina, Fischer, Florian, Flohr, Carsten, Foigt, Nataliya A, Folayan, Morenike Oluwatoyin, Fomenkov, Artem Alekseevich, Freitas, Marisa, Fukumoto, Takeshi, Fuller, John E, Furtado, João M, Gad, Mohamed M, Gakidou, Emmanuela, Gallus, Silvano, Gebrehiwot, Abiyu Mekonnen, Gebremedhin, Ketema Bizuwork, Gething, Peter W, Ghamari, Farhad, Ghashghaee, Ahmad, Gholamian, Asadollah, Gilani, Syed Amir, Gitimoghaddam, Mojgan, Glushkova, Ekaterina Vladimirovna, Gnedovskaya, Elena V, Gopalani, Sameer Vali, Goulart, Alessandra C, Gugnani, Harish Chander, Guo, Yuming, Gupta, Rajeev, Gupta, Subodh Sharan, Haagsma, Juanita A, Haj-Mirzaian, Arvin, Haj-Mirzaian, Arya, Halvaei, Iman, Hamadeh, Randah R, Hamagharib Abdullah, Kanaan, Han, Chieh, Handiso, Demelash Woldeyohanne, Hankey, Graeme J, Haririan, Hamidreza, Haro, Josep Maria, Hasaballah, Ahmed I, Hassanipour, Soheil, Hassankhani, Hadi, Hay, Simon I, Heibati, Behzad, Heidari-Soureshjani, Reza, Henny, Kiana, Henry, Nathaniel J, Herteliu, Claudiu, Heydarpour, Fatemeh, Hole, Michael K, Hoogar, Praveen, Hosgood, H Dean, Hossain, Naznin, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Househ, Mowafa, Hoy, Damian G, Hu, Guoqing, Huda, Tanvir M, Ibitoye, Segun Emmanuel, Ikuta, Kevin S, Ilesanmi, Olayinka Stephen, Ilic, Irena M, Ilic, Milena D, Imani-Nasab, Mohammad Hasan, Islam, Mdmohaimenul, Iso, Hiroyasu, Iwu, Chinwe Juliana, Jaafari, Jalil, Jacobsen, Kathryn H, Jahagirdar, Deepa, Jahanmehr, Nader, Jalali, Amir, Jalilian, Farzad, James, Spencer L, Janjani, Hosna, Jenabi, Ensiyeh, Jha, Ravi Prakash, Jha, Vivekanand, Ji, John S, Jonas, Jost B, Joukar, Farahnaz, Jozwiak, Jacek Jerzy, Jürisson, Mikk, Kabir, Zubair, Kalani, Hamed, Kalankesh, Leila R, Kamiab, Zahra, Kanchan, Tanuj, Kapoor, Neeti, Karch, André, Karimi, Salah Eddin, Karimi, Seyed Asaad, Kassebaum, Nicholas J, Katikireddi, Srinivasa Vittal, Kawakami, Norito, Kayode, Gbenga A, Keiyoro, Peter Njenga, Keller, Cathleen, Khader, Yousef Saleh, Khalid, Nauman, Khan, Ejaz Ahmad, Khan, Maseer, Khang, Young-Ho, Khater, Amir M, Khater, Mona M, Khazaei, Salman, Khazaie, Habibolah, Khodayari, Mohammad Taghi, Khubchandani, Jagdish, Kianipour, Neda, Kim, Cho-il, Kim, Young-Eun, Kim, Yun Jin, Kinfu, Yohanne, Kisa, Adnan, Kisa, Sezer, Kissimova-Skarbek, Katarzyna, Kivimäki, Mika, Komaki, Hamidreza, Kopec, Jacek A, Kosen, Soewarta, Koul, Parvaiz A, Koyanagi, Ai, Kravchenko, Michael A, Krishan, Kewal, Krohn, Kris J, Kuate Defo, Barthelemy, Kumar, G Anil, Kumar, Manasi, Kumar, Pushpendra, Kumar, Vivek, Kusuma, Dian, Kyu, Hmwe Hmwe, La Vecchia, Carlo, Lacey, Ben, Lal, Dharmesh Kumar, Lalloo, Ratilal, Lami, Faris Hasan, Lansky, Sonia, Larson, Samantha Leigh, Larsson, Anders O, Lasrado, Savita, Lassi, Zohra S, Lazarus, Jeffrey V, Lee, Paul H, Lee, Shaun Wen Huey, Leever, Andrew T, Legrand, Kate E, Leonardi, Matilde, Li, Shanshan, Lim, Lee-Ling, Lim, Stephen S, Linn, Shai, Lodha, Rakesh, Logroscino, Giancarlo, Lopez, Alan D, Lopukhov, Platon D, Lotufo, Paulo A, Lozano, Rafael, Lu, Alton, Lunevicius, Raimunda, Madadin, Mohammed, Maddison, Emilie R, Magdy Abd El Razek, Hassan, Magdy Abd El Razek, Muhammed, Mahasha, Phetole Walter, Mahdavi, Mokhtar Mahdavi, Malekzadeh, Reza, Mamun, Abdullah A, Manafi, Navid, Mansour-Ghanaei, Fariborz, Mansouri, Borhan, Mansournia, Mohammad Ali, Mapoma, Chabila Christopher, Martini, Santi, Martins-Melo, Francisco Rogerlândio, Masaka, Anthony, Mastrogiacomo, Claudia I, Mathur, Manu Raj, May, Erin A, Mcalinden, Colm, Mcgrath, John J, Mckee, Martin, Mehndiratta, Man Mohan, Mehri, Fereshteh, Mehta, Kala M, Meitei, Wahengbam Bigyananda, Memiah, Peter T N, Mendoza, Walter, Menezes, Ritesh G, Mengesha, Endalkachew Worku, Mensah, George A, Meretoja, Atte, Meretoja, Tuomo J, Mestrovic, Tomislav, Michalek, Irmina Maria, Mihretie, Kebadnew Mulatu, Miller, Ted R, Mills, Edward J, Milne, George J, Mirrakhimov, Erkin M, Mirzaei, Hamed, Mirzaei, Maryam, Mirzaei-Alavijeh, Mehdi, Misganaw, Awoke Temesgen, Moazen, Babak, Moghadaszadeh, Masoud, Mohamadi, Efat, Mohammad, Dara K, Mohammad, Yousef, Mohammad Gholi Mezerji, Naser, Mohammadbeigi, Abolfazl, Mohammadian-Hafshejani, Abdollah, Mohammadpourhodki, Reza, Mohammed, Hussen, Mohammed, Shafiu, Mohebi, Farnam, Mohseni Bandpei, Mohammad A, Mokari, Amin, Mokdad, Ali H, Momen, Natalie C, Monasta, Lorenzo, Mooney, Meghan D, Moradi, Ghobad, Moradi, Masoud, Moradi-Joo, Mohammad, Moradi-Lakeh, Maziar, Moradzadeh, Rahmatollah, Moraga, Paula, Moreno Velásquez, Ilai, Morgado-da-Costa, Joana, Morrison, Shane Dougla, Mosser, Jonathan F, Mouodi, Simin, Mousavi, Seyyed Meysam, Mousavi Khaneghah, Amin, Mueller, Ulrich Otto, Musa, Kamarul Imran, Muthupandian, Saravanan, Nabavizadeh, Behnam, Naderi, Mehdi, Nagarajan, Ahamarshan Jayaraman, Naghavi, Mohsen, Naghshtabrizi, Behshad, Naik, Gurudatta, Najafi, Farid, Nangia, Vinay, Nansseu, Jobert Richie, Ndwandwe, Duduzile Edith, Negoi, Ionut, Negoi, Ruxandra Irina, Ngunjiri, Josephine W, Nguyen, Huong Lan Thi, Nguyen, Trang Huyen, Nigatu, Yeshambel T, Nikbakhsh, Rajan, Nikpoor, Amin Reza, Nixon, Molly R, Nnaji, Chukwudi A, Nomura, Shuhei, Noubiap, Jean Jacque, Nouraei Motlagh, Soraya, Nowak, Christoph, Oţoiu, Adrian, Odell, Christopher M, Oh, In-Hwan, Oladnabi, Morteza, Olagunju, Andrew T, Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Omar Bali, Ahmed, Ong, Kanyin L, Onwujekwe, Obinna E, Ortiz, Alberto, Otstavnov, Nikita, Otstavnov, Stanislav S, Øverland, Simon, Owolabi, Mayowa O, P A, Mahesh, Padubidri, Jagadish Rao, Pakshir, Keyvan, Palladino, Raffaele, Pana, Adrian, Panda-Jonas, Songhomitra, Park, Jame, Pasupula, Deepak Kumar, Patel, Jenil R, Patel, Sangram Kishor, Patton, George C, Paulson, Katherine R, Pazoki Toroudi, Hamidreza, Pease, Spencer A, Peden, Amy E, Pepito, Veincent Christian Filipino, Peprah, Emmanuel K, Pereira, Alexandre, Pereira, David M, Perico, Norberto, Pigott, David M, Pilgrim, Thoma, Pilz, Tessa M, Piradov, Michael A, Pirsaheb, Meghdad, Pokhrel, Khem Narayan, Postma, Maarten J, Pourjafar, Hadi, Pourmalek, Farshad, Pourshams, Akram, Poznańska, Anna, Prada, Sergio I, Prakash, Sanjay, Preotescu, Liliana, Quazi Syed, Zahiruddin, Rabiee, Mohammad, Rabiee, Navid, Radfar, Amir, Rafiei, Alireza, Raggi, Alberto, Rahman, Muhammad Aziz, Rajabpour-Sanati, Ali, Ram, Pradhum, Ranabhat, Chhabi Lal, Rao, Sowmya J, Rasella, Davide, Rashedi, Vahid, Rastogi, Prateek, Rathi, Priya, Rawal, Lal, Remuzzi, Giuseppe, Renjith, Vishnu, Renzaho, Andre M N, Resnikoff, Serge, Rezaei, Nima, Rezai, Mohammad sadegh, Rezapour, Aziz, Rickard, Jennifer, Roever, Leonardo, Ronfani, Luca, Roshandel, Gholamreza, Rostamian, Morteza, Rubagotti, Enrico, Rwegerera, Godfrey M, Sabour, Siamak, Saddik, Basema, Sadeghi, Ehsan, Sadeghi, Masoumeh, Saeedi Moghaddam, Sahar, Safari, Yahya, Safi, Sare, Safiri, Saeid, Sagar, Rajesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Sajadi, S Mohammad, Salahshoor, Mohammad Reza, Salama, Joseph S, Salamati, Payman, Salem, Marwa R Rashad, Salimi, Yahya, Salomon, Joshua A, Salz, Inbal, Samad, Zainab, Samy, Abdallah M, Sanabria, Juan, Santric-Milicevic, Milena M, Saraswathy, Sivan Yegnanarayana Iyer, Sartorius, Benn, Sarveazad, Arash, Sathian, Brijesh, Sathish, Thirunavukkarasu, Sattin, Davide, Saylan, Mete, Schaeffer, Lauren E, Schiavolin, Silvia, Schwebel, David C, Schwendicke, Falk, Sekerija, Mario, Senbeta, Anbissa Muleta, Senthilkumaran, Subramanian, Sepanlou, Sadaf G, Serván-Mori, Edson, Shabani, Mahsima, Shahabi, Saeed, Shahbaz, Mohammad, Shaheen, Amira A, Shaikh, Masood Ali, Shalash, Ali S, Shams-Beyranvand, Mehran, Shamsi, Mohammadbagher, Shamsizadeh, Morteza, Shannawaz, Mohammed, Sharafi, Kiomar, Sharafi, Zeinab, Sharara, Fablina, Sharma, Rajesh, Shaw, David H, Sheikh, Aziz, Shin, Jae Il, Shiri, Rahman, Shrime, Mark G, Shuval, Kerem, Siabani, Soraya, Sigfusdottir, Inga Dora, Sigurvinsdottir, Rannveig, Silva, Diego Augusto Santo, Simonetti, Biagio, Simpson, Kyle E, Singh, Jasvinder A, Skiadaresi, Eirini, Skryabin, Valentin Yurievich, Soheili, Amin, Sokhan, Anton, Sorensen, Reed J D, Soriano, Joan B, Sorrie, Muluken Bekele, Soyiri, Ireneous N, Spurlock, Emma Elizabeth, Sreeramareddy, Chandrashekhar T, Stockfelt, Leo, Stokes, Mark A, Stubbs, Jacob L, Sudaryanto, Agu, Sufiyan, Mu'awiyyah Babale, Suliankatchi Abdulkader, Rizwan, Sykes, Bryan L, Tabarés-Seisdedos, Rafael, Tabb, Karen M, Tadakamadla, Santosh Kumar, Taherkhani, Amir, Tang, Muming, Taveira, Nuno, Taylor, Heather Jean, Teagle, Whitney L, Tehrani-Banihashemi, Arash, Teklehaimanot, Berhane Fseha, Tessema, Zemenu Tadesse, Thankappan, Kavumpurathu Raman, Thomas, Nihal, Thrift, Amanda G, Titova, Mariya Vladimirovna, Tohidinik, Hamid Reza, Tonelli, Marcello, Topor-Madry, Roman, Topouzis, Foti, Tovani-Palone, Marcos Roberto Roberto, Traini, Eugenio, Tran, Bach Xuan, Travillian, Ravensara, Trias-Llimós, Sergi, Truelsen, Thomas Clement, Tudor Car, Lorainne, Unnikrishnan, Bhaskaran, Upadhyay, Era, Vacante, Marco, Vakilian, Alireza, Valdez, Pascual R, Valli, Alessandro, Vardavas, Constantine, Vasankari, Tommi Juhani, Vasconcelos, Ana Maria Nogale, Vasseghian, Yasser, Veisani, Yousef, Venketasubramanian, Narayanaswamy, Vidale, Simone, Violante, Francesco S, Vlassov, Vasily, Vollset, Stein Emil, Vos, Theo, Vujcic, Isidora S, Vukovic, Ana, Vukovic, Rade, Waheed, Yasir, Wallin, Mitchell Taylor, Walters, Magdalene K, Wang, Hongbo, Wang, Yuan-Pang, Watson, Stefanie, Wei, Jingkai, Weiss, Jordan, Weldesamuel, Girmay Teklay, Werdecker, Andrea, Westerman, Ronny, Whiteford, Harvey A, Wiangkham, Taweewat, Wiens, Kirsten E, Wijeratne, Tissa, Wiysonge, Charles Shey, Wojtyniak, Bogdan, Wolfe, Charles D A, Wondmieneh, Adam Belay, Wool, Eve E, Wu, Ai-Min, Wu, Junjie, Xu, Gelin, Yamada, Tomohide, Yamagishi, Kazumasa, Yano, Yuichiro, Yaya, Sanni, Yazdi-Feyzabadi, Vahid, Yearwood, Jamal A, Yeheyis, Tomas Y, Yilgwan, Christopher Sabo, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Yoosefi Lebni, Javad, York, Hunter W, Younis, Mustafa Z, Younker, Theodore Patrick, Yousefi, Zabihollah, Yousefinezhadi, Taraneh, Yousuf, Abdilahi Yousuf, Yusefzadeh, Hasan, Zahirian Moghadam, Telma, Zakzuk, Josefina, Zaman, Sojib Bin, Zamani, Mohammad, Zamanian, Maryam, Zandian, Hamed, Zhang, Zhi-Jiang, Zheng, Peng, Zhou, Maigeng, Ziapour, Arash, Murray, Christopher J L, Collaborators, GBD 2019 Demographics, GBD 2019 Demographics Collaborator, Violante FS, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Microbes in Health and Disease (MHD), Department of Earth Systems Analysis, Biomechanical Engineering, TechMed Centre, Biomolecular Nanotechnology, Research Methodology, Measurement and Data Analysis, Materials Science and Technology of Polymers, Inorganic Materials Science, MESA+ Institute, Biomedical and Environmental Sensorsystems, Mesoscale Chemical Systems, Faculty of Engineering Technology, Nonlinear Solid Mechanics, Digital Society Institute, Pervasive Systems, Nanobiophysics, Faculty of Geo-Information Science and Earth Observation, Multi Scale Mechanics, Engineering Fluid Dynamics, Physics of Complex Fluids, Developmental BioEngineering, Physics of Fluids, Elastomer Technology and Engineering, Medical Cell Biophysics, European Membrane Institute, Department of Earth Observation Science, Biomaterials Science and Technology, Sustainable Process Technology, Department of Urban and Regional Planning and Geo-Information Management, Department of Natural Resources, XUV Optics, Databases (Former), Department of Water Resources, Psychology, Health & Technology, Membrane Science & Technology, Department of Public Health, Clinicum, HUS Neurocenter, HUS Comprehensive Cancer Center, and Environmental Sciences
Subjects: Male, very elderly, Demographic transition, HALE, 030204 cardiovascular system & hematology, preschool child, Global Burden of Disease, Carga Global de Enfermedades, 0302 clinical medicine, newborn, Risk Factors, Surveys and Questionnaires, and Risk Factors Study, 80 and over, 030212 general & internal medicine, Birth Rate, Child, Migration, 11 Medical and Health Sciences, Aged, 80 and over, education.field_of_study, Injuries, Geography, Mortality rate, 1. No poverty, DEATH, Censuses, General Medicine, SDG 10 - Reduced Inequalities, Middle Aged, Demographic analysis, 3142 Public health care science, environmental and occupational health, 3. Good health, demographic analysis, Estilo de Vida Saludable, risk factor, Child, Preschool, Demography/statistics & numerical data, Global Burden of Diseases, Injuries, Risk Factors, Fertility, Mortality, Migration, Population, epidemiology, Female, A990 Medicine and Dentistry not elsewhere classified, CHILD-MORTALITY, Live Birth, Global Health Metrics, TRANSITION, demographics, GBD, fertility, mortality, hale, Adult, Adolescent, Total fertility rate, Population, Global Burden of Diseases, Injuries, and Risk Factors Study, Birth rate, 03 medical and health sciences, Young Adult, Life Expectancy, SDG 3 - Good Health and Well-being, General & Internal Medicine, SYSTEMATIC ANALYSIS, Demografía, Humans, Global Burden of Disease Study, human, Mortality, education, Preschool, Aged, Demography, Spatial Analysis, questionnaire, Infant, Newborn, Klinisk medicin, HIV, Infant, Global Burden of Diseases, sex-specific fertility, Live Birth/epidemiology, purl.org/pe-repo/ocde/ford#3.02.00 [https], MODEL, Fertilidad, Fertility, Demographic change, Life expectancy, NA, global disease burden, Clinical Medicine, population research
Abstract: Background Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10-14 and 50-54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a Bayesian hierarchical cohort component model that analysed estimated age-specific fertility and mortality rates along with 1250 censuses and 747 population registry years. We classified location-years into seven categories on the basis of the natural rate of increase in population (calculated by subtracting the crude death rate from the crude birth rate) and the net migration rate. We computed healthy life expectancy (HALE) using years lived with disability (YLDs) per capita, life tables, and standard demographic methods. Uncertainty was propagated throughout the demographic estimation process, including fertility, mortality, and population, with 1000 draw-level estimates produced for each metric. Findings The global TFR decreased from 2.72 (95% uncertainty interval [UI] 2.66-2.79) in 2000 to 2.31 (2.17-2.46) in 2019. Global annual livebirths increased from 134.5 million (131.5-137.8) in 2000 to a peak of 139.6 million (133.0-146.9) in 2016. Global livebirths then declined to 135.3 million (127.2-144.1) in 2019. Of the 204 countries and territories included in this study, in 2019, 102 had a TFR lower than 2.1, which is considered a good approximation of replacement-level fertility. All countries in sub-Saharan Africa had TFRs above replacement level in 2019 and accounted for 27.1% (95% UI 26.4-27.8) of global livebirths. Global life expectancy at birth increased from 67.2 years (95% UI 66.8-67.6) in 2000 to 73.5 years (72.8-74.3) in 2019. The total number of deaths increased from 50.7 million (49.5-51.9) in 2000 to 56.5 million (53.7-59.2) in 2019. Under-5 deaths declined from 9.6 million (9.1-10.3) in 2000 to 5.0 million (4.3-6.0) in 2019. Global population increased by 25.7%, from 6.2 billion (6.0-6.3) in 2000 to 7.7 billion (7.5-8.0) in 2019. In 2019, 34 countries had negative natural rates of increase; in 17 of these, the population declined because immigration was not sufficient to counteract the negative rate of decline. Globally, HALE increased from 58.6 years (56.1-60.8) in 2000 to 63.5 years (60.8-66.1) in 2019. HALE increased in 202 of 204 countries and territories between 2000 and 2019. Interpretation Over the past 20 years, fertility rates have been dropping steadily and life expectancy has been increasing, with few exceptions. Much of this change follows historical patterns linking social and economic determinants, such as those captured by the GBD Socio-demographic Index, with demographic outcomes. More recently, several countries have experienced a combination of low fertility and stagnating improvement in mortality rates, pushing more populations into the late stages of the demographic transition. Tracking demographic change and the emergence of new patterns will be essential for global health monitoring. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.
Published: 2020

3. The first report of Morishitium vagum (Trematoda: Cyclocoelidae) in Turdus merula in Iran

Author: Kalani H., Kalani F., Faridnia R., Pestechian N., Mohaghegh M. A., Mirzaei F., Sharif M., and Daryani A.
Subjects: morishitium vagum, turdus merula, iran, Microbiology, QR1-502
Abstract: This paper describes a trematode isolated from the air sacs of a common blackbird (Turdus merula) by the authors in Qaemshahr city, Mazandaran province, north of Iran. The specimens were in the best form to make whole-mounts for species identification. The identified species was Morishitium vagum (Morishita 1924) Witenberg 1928, belonging to the family Cyclocoelidae Stossich 1902, according to morphologic and morphometric characters, as explained in references. This is the first report of a species belonging to the family Cyclocoelidae in Iran, and the first report of this type-species isolated from Turdus merula in the world.
Published: 2015
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4. Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Author: Kinyoki, D, Ross, J, Lazzar-Atwood, A, Munro, S, Schaeffer, L, Abbasalizad-Farhangi, M, Abbasi, M, Abbastabar, H, Abdelalim, A, Abdoli, A, Abdollahi, M, Abdollahpour, I, Abdulkader, R, Abebe, N, Abebo, T, Abegaz, K, Abolhassani, H, Abreu, L, Abrigo, M, Abushouk, A, Accrombessi, M, Acharya, D, Adabi, M, Adebiyi, A, Adedeji, I, Adekanmbi, V, Adeoye, A, Adetokunboh, O, Adham, D, Aduroja, P, Advani, S, Afarideh, M, Aghaali, M, Agrawal, A, Ahmad, T, Ahmadi, K, Ahmadi, S, Ahmed, M, Ahmed, R, Ajumobi, O, Akal, C, Akalu, T, Akinyemiju, T, Akombi, B, Al-Aly, Z, Alam, S, Alamene, G, Alanzi, T, Rabanal, J, Alema, N, Ali, B, Ali, M, Alijanzadeh, M, Alinia, C, Alipour, V, Alizade, H, Aljunid, S, Almasi, A, Almasi-Hashiani, A, Al-Mekhlafi, H, Al-Raddadi, R, Altirkawi, K, Alvis-Guzman, N, Alvis-Zakzuk, N, Amare, A, Amegah, A, Amini, S, Rarani, M, Amiri, F, Amit, A, Anber, N, Andrei, C, Ansari, F, Ansari-Moghaddam, A, Anteneh, Z, Antonio, C, Antriyandarti, E, Anvari, D, Anwer, R, Appiah, S, Arabloo, J, Arab-Zozani, M, Araya, E, Arefi, Z, Aremu, O, Arnlov, J, Arzani, A, Asadi-Aliabadi, M, Asadi-Pooya, A, Asgari, S, Asghari, B, Ashagre, A, Asrat, A, Ataeinia, B, Atalay, H, Atnafu, D, Atout, M, Ausloos, M, Avokpaho, E, Awasthi, A, Quintanilla, B, Ayanore, M, Aynalem, Y, Azadmehr, A, Azari, S, Azarian, G, Azene, Z, Babaee, E, Badawi, A, Badiye, A, Bahrami, M, Baig, A, Bakhtiari, A, Bakkannavar, S, Balakrishnan, S, Bali, A, Banach, M, Banik, P, Baradaran-Seyed, Z, Baraki, A, Barboza, M, Barnighausen, T, Barua, L, Basaleem, H, Basu, S, Bayati, M, Bayih, M, Baynes, H, Bedi, N, Behzadifar, M, Bekele, Y, Bennett, D, Berbada, D, Berhe, K, Berhe, A, Berman, A, Bernstein, R, Bhageerathy, R, Bhandari, D, Bharadwaj, P, Bhattacharjee, N, Bhattacharyya, K, Bijani, A, Bikbov, B, Bilano, V, Bililign, N, Sayeed, M, Birara, S, Birhane, M, Birhanu, M, Biswas, R, Bitew, Z, Bogale, K, Bohlouli, S, Bolla, S, Boloor, A, Borzi, A, Borzouei, S, Brady, O, Bragazzi, N, Braithwaite, D, Briko, N, 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Lebedev, G, Lee, P, Lee, S, Leili, M, Letourneau, I, Lewycka, S, Li, S, Lim, L, Linn, S, Liu, S, Lodha, R, Longbottom, J, Lopez, J, Lorkowski, S, Macarayan, E, Madadin, M, El Razek, H, El Razek, M, Maghavani, D, Mahasha, P, Mahotra, N, Maled, V, Maleki, A, Maleki, S, Malta, D, Manafi, A, Manafi, F, Manafi, N, Manohar, N, Mansour-Ghanaei, F, Mansouri, B, Mansournia, M, Mapoma, C, Marami, D, Marczak, L, Arnedo, C, Martins-Melo, F, Masaka, A, Massenburg, B, Maulik, P, Mayala, B, Mazidi, M, Mehndiratta, M, Mehri, F, Mehta, K, Meitei, W, Mekonnen, F, Mekonnen, T, Meles, G, Meles, H, Melese, A, Mendoza, W, Menezes, R, Mengesha, M, Mensah, G, Meretoja, T, Miazgowski, T, Kostova, N, Miller, T, Mills, E, Mini, G, Mir, S, Miri, M, Mirjalali, H, Mirrakhimov, E, Mirzaei, H, Mirzaei, M, Mirzaei, R, Mirzaei-Alavijeh, M, Mithra, P, Moazen, B, Mohamadi, E, Mohamadi-Bolbanabad, A, Mohammad, K, Mohammad, Y, Mohammad, D, Darwesh, A, Mezerji, N, Mohammadian-Hafshejani, A, Mohammadnia-Afrouzi, M, 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K., Ross J. M., Lazzar-Atwood A., Munro S. B., Schaeffer L. E., Abbasalizad-Farhangi M., Abbasi M., Abbastabar H., Abdelalim A., Abdoli A., Abdollahi M., Abdollahpour I., Abdulkader R. S., Abebe N. D., Abebo T. A., Abegaz K. H., Abolhassani H., Abreu L. G., Abrigo M. R. M., Abushouk A. I., Accrombessi M. M. K., Acharya D., Adabi M., Adebiyi A. O., Adedeji I. A., Adekanmbi V., Adeoye A. M., Adetokunboh O. O., Adham D., Aduroja P. E., Advani S. M., Afarideh M., Aghaali M., Agrawal A., Ahmad T., Ahmadi K., Ahmadi S., Ahmed M. B., Ahmed R., Ajumobi O., Akal C. G., Akalu T. Y., Akinyemiju T., Akombi B., Al-Aly Z., Alam S., Alamene G. M., Alanzi T. M., Rabanal J. E. A., Alema N. M., Ali B. A., Ali M., Alijanzadeh M., Alinia C., Alipour V., Alizade H., Aljunid S. M., Almasi A., Almasi-Hashiani A., Al-Mekhlafi H. M., Al-Raddadi R. M., Altirkawi K., Alvis-Guzman N., Alvis-Zakzuk N. J., Amare A. T., Amegah A. K., Amini S., Rarani M. A., Amiri F., Amit A. M. L., Anber N. H., Andrei C. 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V., Bhattacharyya K., Bijani A., Bikbov B., Bilano V., Bililign N., Sayeed M. S. B., Birara S., Birhane M. B. B., Birhanu M., Biswas R. K., Bitew Z. W., Bogale K. A., Bohlouli S., Bolla S. R., Boloor A., Borzi A. M., Borzouei S., Brady O. J., Bragazzi N. L., Braithwaite D., Briko N. I., Britton G., Budhathoki S. S., Nagaraja S. B., Busse R., Butt Z. A., Cahuana-Hurtado L., Camera L. A., Campos-Nonato I. R., Cano J., Car J., Cardenas R., Carrero J. J., Carvalho F., Castaldelli-Maia J. M., Castaneda-Orjuela C. A., Castro F., Cerin E., Chansa C., Charan J., Chatterjee P., Chattu V. K., Chauhan B. G., Chavshin A. R., Chehrazi M., Chichiabellu T. Y., Chin K. L., Christopher D. J., Chu D. -T., Cicuttini F. M., Collison M. L., Cork M. A., Cormier N., Cortesi P. A., Costa V. M., Dadi A. F. F., Dagnew B., Dahlawi S. M. A., Damiani G., Darwish A. H., Daryani A., Das J. K., Gupta R. D., Davila-Cervantes C., Davis Weaver N., Leo D. D., Neve J. -W. D., Demeke F. M., Demis A. B., Demissie D. 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T., Filip I., Fischer F., Flohr C., Foigt N. A., Folayan M. O., Fomenkov A. A., Foroutan M., Forster J., Francis J. M., Fukumoto T., Gayesa R. T., Geberemariyam B. S., Gebrehiwot T. T., Gebremariam H., Gebremariam K. T., Gebremedhin K. B. B., Gebremeskel G. G., Gebreslassie A. A. A., Gebretsadik G. G. G., Gedefaw G. A., Geramo Y. C. D., Gesesew H. A., Geta B., Getenet A. B., Gezae K. E., Ghaffarifar F., Ghafourifard M., Ghajar A., Ghajarzadeh M., Ghashghaee A., Ghiasvand H., Gholamian A., Gilani S. A., Gill T. K., Ginawi I. A., Goli S., Gomes N. G. M., Gopalani S. V., Goudarzi H., Goulart A. C., Govindakarnavar A., Grada A., Grivna M., Guimaraes R. A., Guled R. A., Guo Y., Gupta R., Hafezi-Nejad N., Haile M. T., Haj-Mirzaian A., Hall B. J., Halvaei I., Hamadeh R. R., Hamidi Y., Handiso D. W., Hankey G. J., Haririan H., Hariyani N., Hasaballah A. I., Hasan M. M., Hasankhani M., Hasanpoor E., Hasanzadeh A., Hashemian M., Hassanipour S., Hassen H. Y., Havmoeller R., Hawkes C., Hayat K., Hayelom D. H., Heidari B., Heidari-Soureshjani R., Hendrie D., Henok A., Henry N. J., Herrero M., Herteliu C., Heydarpour F., de Hidru H. D., Hoang C. L., Hoek H. W., Hole M. K., Holla R., Hollerich G., Rad E. H., Hong S. H., Hoogar P., Horino M., Hossain N., Hosseini M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Housseh M., Hsairi M., Hu G., Huda T. M., Humayun A., Hwang B. -F., Ibitoye S. E., Ilesanmi O. S., Ilic M. D., Imani-Nasab M. H., Inbaraj L. R., Iqbal U., Irvani S. S. N., Islam S. M. S., Iwu C. C. D., Iwu C. J., Izadi N., Jaafari J., Jaca A., Jadidi-Niaragh F., Balalami N. J., Jafarinia M., Jahani M. A., Jakovljevic M., Jalali A., Jalilian F., Jayatilleke A. U., Jeemon P., Jehan F., Jenabi E., Jha R. P., Jha V., Ji J. S., Jia P., John O., John-Akinola Y. O., Johnson K. B., Jonas J. B., Joseph N., Joukar F., Jozwiak J. J., Jungari S. B., Jurisson M., Kabir A., Kabir Z., Kahsay A., Kahssay M., Kalani H., Kalankesh L. L., Kalhor R., Kamiab Z., Kanchan T., Kapil U., Kapoor N., Karami M., Matin B. K., Karch A., Karim M. A., Karki S., Kasaeian A., Kasahun G. G., Kasaye H. K., Kassa T. D., Kassaye H. G., Kassebaum N. J., Karyani A. K., Kengne A. P., Ketema D. B., Khader Y. S., Khafaie M. A., Khaksarian M., Khalid N., Khalil I. A., Khalilov R., Khan A., Khan E. A., Khan M. N., Khan M. S., Khatab K., Khater A., Khater M. M., Khatib M. N., Khayamzadeh M., Khazaei-Pool M., Khazaei M., Khazaei S., Khodayari M. T., Khosravi M. H., Khundkar R., Kiadaliri A., Kianipour N., Kiirithio D. N., Kim Y. J., Kimokoti R. W., Kisa A., Kisa S., Kolola T., Komaki H., Kondlahalli S. K. M., Koolivand A., Koul P. A., Koyanagi A., Kraemer M. U. G., Krishan K., Krohn K. J., Kugbey N., Kumar M., Kumar P., Kumar V., Kurmi O. P., Kuti O., Vecchia C. L., Lacey B., Lad D. P., Lal A., Lal D. K., Lami F. H., Lamichhane P., Lang J. J., Lansingh V. C., Lasrado S., Lebedev G., Lee P. H., Lee S. W. H., Leili M., Letourneau I. D., Lewycka S., Li S., Lim L. -L., Linn S., Liu S., Lodha R., Longbottom J., Lopez J. C. F., Lorkowski S., Macarayan E. R. K., Madadin M., El Razek H. M. A., El Razek M. M. A., Maghavani D. P., Mahasha P. W., Mahotra N. B., Maled V., Maleki A., Maleki S., Malta D. C., Manafi A., Manafi F., Manafi N., Manohar N. D., Mansour-Ghanaei F., Mansouri B., Mansournia M. A., Mapoma C. C., Marami D., Marczak L. B., Arnedo C. A. M., Martins-Melo F. R., Masaka A., Massenburg B. B., Maulik P. K., Mayala B. K., Mazidi M., Mehndiratta M. M., Mehri F., Mehta K. M., Meitei W. B., Mekonnen F. A., Mekonnen T., Meles G. G., Meles H. G., Melese A., Mendoza W., Menezes R. G., Mengesha M. B., Mensah G. A., Meretoja T. J., Miazgowski T., Kostova N. M., Miller T. R., Mills E. J., Mini G. K., Mir S. M., Miri M., Mirjalali H., Mirrakhimov E. M., Mirzaei H., Mirzaei M., Mirzaei R., Mirzaei-Alavijeh M., Mithra P., Moazen B., Mohamadi E., Mohamadi-Bolbanabad A., Mohammad K. A., Mohammad Y., Mohammad D. K., Darwesh A. M., Mezerji N. M. G., Mohammadian-Hafshejani A., Mohammadnia-Afrouzi M., Mohammadoo-Khorasani M., Mohammadpourhodki R., Mohammed S., Mohammed J. A., Mohammed A. S., Mohebi F., Mokari A., Mokdad A. H., Montanez J. C., Montero-Zamora P. A., Moodley Y., Moossavi M., Moradi G., Moradi M., Moradi Y., Moradi-Joo M., Moradi-Lakeh M., Moradpour F., Moradzadeh R., Moraga P., Morrison S. D., Mosapour A., Mosser J. F., Mouodi S., Khaneghah A. M., Mozaffarian D., Mueller U. O., Murray C. J. L., Murthy G. V. S., Musa K. I., Mustafa G., Muthupandian S., Nabavizadeh B., Naderi M., Nadkarni G. N., Nagarajan A. J., Naghavi M., Naheed A., Naik G., Najafi F., Nansseu J. R., Narayan K. M. V., Nascimento B. R., Nayak V., Nazari J., Ndwandwe D. E., Negoi I., Negoi R. I., Ngunjiri J. W., Nguyen C. T., Nguyen H. L. T., Nigatu D., Nigatu Y. T., Nikbakhsh R., Ningrum D. N. A., Nnaji C. A., Nong V. M., Noubiap J. J., Nowak C., Oancea B., Ofori-Asenso R., Oghenetega O. 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R., VanderHeide J., Varavikova E., Varughese S., Vasankari T. J., Vasseghian Y., Veisani Y., Venkatesh S., Venketasubramanian N., Verma M., Vidale S., Violante F. S., Vlassov V., Vollmer S., Vukovic R., Waheed Y., Wang H., Wang Y., Wang Y. -P., Weldesamuel G. T., Werdecker A., Wiangkham T., Wiens K. E., Wijeratne T., Wolde H. F., Wondafrash D. Z., Wonde T. E., Wondmieneh A. B., Wu A. -M., Xu G., Yadegar A., Yadollahpour A., Jabbari S. H. Y., Yamada T., Yano Y., Yaya S., Yazdi-Feyzabadi V., Yeshaneh A., Yeshaw Y., Yeshitila Y. G., Yilma M. T., Yip P., Yonemoto N., Yoon S. -J., Youm Y., Younis M. Z., Yousefi Z., Yousof H. -A. S. A., Yu C., Yusefzadeh H., Moghadam T. Z., Zaki L., Zaman S. B., Zamani M., Zamanian M., Zandian H., Zarafshan H., Zepro N. B., Zerfu T. A., Zewale T. A., Zhang Y., Zhang Z. -J., Zhao X. -J., Zodpey S., Zomorodian K., Zotor F. B., Afshin A., and Hay S. I.
Abstract: A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025. Prevalence of overweight increased from 5.2% (30 (22.8–38.5) million) in 2000 to 6.0% (55.5 (44.8–67.9) million) children aged under 5 years in 2017. Areas most affected by double burden of malnutrition were located in Indonesia, Thailand, southeastern China, Botswana, Cameroon and central Nigeria. Our estimates provide a new perspective to researchers, policy makers and public health agencies in their efforts to address this global childhood syndemic.
Published: 2020

5. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author: Vos, T, Lim, S, Abbafati, C, Abbas, K, Abbasi, M, Abbasifard, M, Abbasi-Kangevari, M, Abbastabar, H, Abd-Allah, F, Abdelalim, A, Abdollahi, M, Abdollahpour, I, Abolhassani, H, Aboyans, V, Abrams, E, Abreu, L, Abrigo, M, Abu-Raddad, L, Abushouk, A, Acebedo, A, Ackerman, I, Adabi, M, Adamu, A, Adebayo, O, Adekanmbi, V, Adelson, J, Adetokunboh, O, Adham, D, Afshari, M, Afshin, A, Agardh, E, Agarwal, G, Agesa, K, Aghaali, M, Aghamir, S, Agrawal, A, Ahmad, T, Ahmadi, A, Ahmadi, M, Ahmadieh, H, Ahmadpour, E, Akalu, T, Akinyemi, R, Akinyemiju, T, Akombi, B, Al-Aly, Z, Alam, K, Alam, N, Alam, S, Alam, T, Alanzi, T, Albertson, S, Alcalde-Rabanal, J, Alema, N, Ali, M, Ali, S, Alicandro, G, Alijanzadeh, M, Alinia, C, Alipour, V, Aljunid, S, Alla, F, Allebeck, P, Almasi-Hashiani, A, Alonso, J, Al-Raddadi, R, Altirkawi, K, Alvis-Guzman, N, Alvis-Zakzuk, N, Amini, S, Amini-Rarani, M, Aminorroaya, A, Amiri, F, Amit, A, Amugsi, D, Amul, G, Anderlini, D, Andrei, C, Andrei, T, Anjomshoa, M, 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Abstract: Background: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods: GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw value
Published: 2020

6. Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author: Abbafati, C, Abbas, K, Abbasi-Kangevari, M, Abd-Allah, F, Abdelalim, A, Abdollahi, M, Abdollahpour, I, Abegaz, K, Abolhassani, H, Aboyans, V, Abreu, L, Abrigo, M, Abualhasan, A, Abu-Raddad, L, Abushouk, A, Adabi, M, Adekanmbi, V, Adeoye, A, Adetokunboh, O, Adham, D, Advani, S, Afshin, A, Agarwal, G, Aghamir, S, Agrawal, A, Ahmad, T, Ahmadi, K, Ahmadi, M, Ahmadieh, H, Ahmed, M, Akalu, T, Akinyemi, R, Akinyemiju, T, Akombi, B, Akunna, C, Alahdab, F, Al-Aly, Z, Alam, K, Alam, S, Alam, T, Alanezi, F, Alanzi, T, Alemu, B, Alhabib, K, Ali, M, Ali, S, Alicandro, G, Alinia, C, Alipour, V, Alizade, H, Aljunid, S, Alla, F, Allebeck, P, Almasi-Hashiani, A, Al-Mekhlafi, H, Alonso, J, Altirkawi, K, Amini-Rarani, M, Amiri, F, Amugsi, D, Ancuceanu, R, Anderlini, D, Anderson, J, Andrei, C, Andrei, T, Angus, C, Anjomshoa, M, Ansari, F, Ansari-Moghaddam, A, Antonazzo, I, Antonio, C, Antony, C, Antriyandarti, E, Anvari, D, Anwer, R, Appiah, S, Arabloo, J, Arab-Zozani, M, Aravkin, A, Ariani, F, Armoon, B, Arnlov, J, Arzani, A, Asadi-Aliabadi, M, Asadi-Pooya, A, Ashbaugh, C, Assmus, M, Atafar, Z, Atnafu, D, Atout, M, Ausloos, F, Ausloos, M, Ayala Quintanilla, B, Ayano, G, Ayanore, M, Azari, S, Azarian, G, Azene, Z, Badawi, A, Badiye, A, Bahrami, M, Bakhshaei, M, Bakhtiari, A, Bakkannavar, S, Baldasseroni, A, Ball, K, Ballew, S, Balzi, D, Banach, M, Banerjee, S, Bante, A, Baraki, A, Barker-Collo, S, Barnighausen, T, Barrero, L, Barthelemy, C, Barua, L, Basu, S, Baune, B, Bayati, M, Becker, J, Bedi, N, Beghi, E, Bejot, Y, Bell, M, Bennitt, F, Bensenor, I, Berhe, K, Berman, A, Bhagavathula, A, Bhageerathy, R, Bhala, N, Bhandari, D, Bhattacharyya, K, Bhutta, Z, Bijani, A, Bikbov, B, Bin Sayeed, M, Biondi, A, Birihane, B, Bisignano, C, Biswas, R, Bitew, H, Bohlouli, S, Bohluli, M, Boon-Dooley, A, Borges, G, Borzi, A, Borzouei, S, Bosetti, C, Boufous, S, Braithwaite, D, Brauer, M, Breitborde, N, Breitner, S, Brenner, H, Briant, P, Briko, A, Briko, N, Britton, G, Bryazka, D, Bumgarner, B, Burkart, K, Burnett, R, Burugina Nagaraja, S, Butt, Z, Caetano Dos Santos, F, Cahill, L, Camera, L, Campos-Nonato, I, Cardenas, R, Carreras, G, Carrero, J, Carvalho, F, Castaldelli-Maia, J, Castaneda-Orjuela, C, Castelpietra, G, Castro, F, Causey, K, Cederroth, C, Cercy, K, Cerin, E, Chandan, J, Chang, K, Charlson, F, Chattu, V, Chaturvedi, S, Cherbuin, N, Chimed-Ochir, O, Cho, D, Choi, J, Christensen, H, Chu, D, Chung, M, Chung, S, Cicuttini, F, Ciobanu, L, Cirillo, M, Classen, T, Cohen, A, Compton, K, Cooper, O, Costa, V, Cousin, E, Cowden, R, Cross, D, Cruz, J, Dahlawi, S, Damasceno, A, Damiani, G, Dandona, L, Dandona, R, Dangel, W, Danielsson, A, Dargan, P, Darwesh, A, Daryani, A, Das, J, Das Gupta, R, das Neves, J, Davila-Cervantes, C, Davitoiu, D, De Leo, D, Degenhardt, L, Delang, M, Dellavalle, R, Demeke, F, Demoz, G, Demsie, D, Denova-Gutierrez, E, Dervenis, N, Dhungana, G, Dianatinasab, M, Dias da Silva, D, Diaz, D, Dibaji Forooshani, Z, Djalalinia, S, Do, H, Dokova, K, Dorostkar, F, Doshmangir, L, Driscoll, T, Duncan, B, Duraes, A, Eagan, A, Edvardsson, D, El Nahas, N, El Sayed, I, El Tantawi, M, Elbarazi, I, Elgendy, I, El-Jaafary, S, Elyazar, I, Emmons-Bell, S, Erskine, H, Eskandarieh, S, Esmaeilnejad, S, Esteghamati, A, Estep, K, Etemadi, A, Etisso, A, Fanzo, J, Farahmand, M, Fareed, M, Faridnia, R, Farioli, A, Faro, A, Faruque, M, Farzadfar, F, Fattahi, N, Fazlzadeh, M, Feigin, V, Feldman, R, Fereshtehnejad, S, Fernandes, E, Ferrara, G, Ferrari, A, Ferreira, M, Filip, I, Fischer, F, Fisher, J, Flor, L, Foigt, N, Folayan, M, Fomenkov, A, Force, L, Foroutan, M, Franklin, R, Freitas, M, Fu, W, Fukumoto, T, Furtado, J, Gad, M, Gakidou, E, Gallus, S, Garcia-Basteiro, A, Gardner, W, Geberemariyam, B, Ayalew Gebreslassie, A, Geremew, A, Gershberg Hayoon, A, Gething, P, Ghadimi, M, Ghadiri, K, Ghaffarifar, F, Ghafourifard, M, Ghamari, F, Ghashghaee, A, Ghiasvand, H, Ghith, N, Gholamian, A, Ghosh, R, Gill, P, Ginindza, T, Giussani, G, Gnedovskaya, E, Goharinezhad, S, Gopalani, S, Gorini, G, Goudarzi, H, Goulart, A, Greaves, F, Grivna, M, Grosso, G, Gubari, M, Gugnani, H, Guimaraes, R, Guled, R, Guo, G, Guo, Y, Gupta, R, Gupta, T, Haddock, B, Hafezi-Nejad, N, Hafiz, A, Haj-Mirzaian, A, Hall, B, Halvaei, I, Hamadeh, R, Hamidi, S, Hammer, M, Hankey, G, Haririan, H, Haro, J, Hasaballah, A, Hasan, M, Hasanpoor, E, Hashi, A, Hassanipour, S, Hassankhani, H, Havmoeller, R, Hay, S, Hayat, K, Heidari, G, Heidari-Soureshjani, R, Henrikson, H, Herbert, M, Herteliu, C, Heydarpour, F, Hird, T, Hoek, H, Holla, R, Hoogar, P, Hosgood, H, Hossain, N, Hosseini, M, Hosseinzadeh, M, Hostiuc, M, Hostiuc, S, Househ, M, Hsairi, M, Hsieh, V, Hu, G, Hu, K, Huda, T, Humayun, A, Huynh, C, Hwang, B, Iannucci, V, Ibitoye, S, Ikeda, N, Ikuta, K, Ilesanmi, O, Ilic, I, Ilic, M, Inbaraj, L, Ippolito, H, Iqbal, U, Irvani, S, Irvine, C, Islam, M, Islam, S, Iso, H, Ivers, R, Iwu, C, Iyamu, I, Jaafari, J, Jacobsen, K, Jafari, H, Jafarinia, M, Jahani, M, Jakovljevic, M, Jalilian, F, James, S, Janjani, H, Javaheri, T, Javidnia, J, Jeemon, P, Jenabi, E, Jha, R, Jha, V, Ji, J, Johansson, L, John, O, John-Akinola, Y, Johnson, C, Jonas, J, Joukar, F, Jozwiak, J, Jurisson, M, Kabir, A, Kabir, Z, Kalani, H, Kalani, R, Kalankesh, L, Kalhor, R, Kanchan, T, Kapoor, N, Matin, B, Karch, A, Karim, M, Kassa, G, Katikireddi, S, Kayode, G, Kazemi Karyani, A, Keiyoro, P, Keller, C, Kemmer, L, Kendrick, P, Khalid, N, Khammarnia, M, Khan, E, Khan, M, Khatab, K, Khater, M, Khatib, M, Khayamzadeh, M, Khazaei, S, Kieling, C, Kim, Y, Kimokoti, R, Kisa, A, Kisa, S, Kivimaki, M, Knibbs, L, Knudsen, A, Kocarnik, J, Kochhar, S, Kopec, J, Korshunov, V, Koul, P, Koyanagi, A, Kraemer, M, Krishan, K, Krohn, K, Kromhout, H, Kuate Defo, B, Kumar, G, Kumar, V, Kurmi, O, Kusuma, D, La Vecchia, C, Lacey, B, Lal, D, Lalloo, R, Lallukka, T, Lami, F, Landires, I, Lang, J, Langan, S, Larsson, A, Lasrado, S, Lauriola, P, Lazarus, J, Lee, P, Lee, S, Legrand, K, Leigh, J, Leonardi, M, Lescinsky, H, Leung, J, Levi, M, Li, S, Lim, L, Linn, S, Liu, S, Liu, Y, Lo, J, Lopez, A, Lopez, J, Lopukhov, P, Lorkowski, S, Lotufo, P, Lu, A, Lugo, A, Maddison, E, Mahasha, P, Mahdavi, M, Mahmoudi, M, Majeed, A, Maleki, A, Maleki, S, Malekzadeh, R, Malta, D, Mamun, A, Manda, A, Manguerra, H, Mansour-Ghanaei, F, Mansouri, B, Mansournia, M, Mantilla Herrera, A, Maravilla, J, Marks, A, Martin, R, Martini, S, Martins-Melo, F, Masaka, A, Masoumi, S, Mathur, M, Matsushita, K, Maulik, P, Mcalinden, C, Mcgrath, J, Mckee, M, Mehndiratta, M, Mehri, F, Mehta, K, Memish, Z, Mendoza, W, Menezes, R, Mengesha, E, Mereke, A, Mereta, S, Meretoja, A, Meretoja, T, Mestrovic, T, Miazgowski, B, Miazgowski, T, Michalek, I, Miller, T, Mills, E, Mini, G, Miri, M, Mirica, A, Mirrakhimov, E, Mirzaei, H, Mirzaei, M, Mirzaei, R, Mirzaei-Alavijeh, M, Misganaw, A, Mithra, P, Moazen, B, Mohammad, D, Mohammad, Y, Mohammad Gholi Mezerji, N, Mohammadian-Hafshejani, A, Mohammadifard, N, Mohammadpourhodki, R, Mohammed, A, Mohammed, H, Mohammed, J, Mohammed, S, Mokdad, A, Molokhia, M, Monasta, L, Mooney, M, Moradi, G, Moradi, M, Moradi-Lakeh, M, Moradzadeh, R, Moraga, P, Morawska, L, Morgado-Da-Costa, J, Morrison, S, Mosapour, A, Mosser, J, Mouodi, S, Mousavi, S, Khaneghah, A, Mueller, U, Mukhopadhyay, S, Mullany, E, Musa, K, Muthupandian, S, Nabhan, A, Naderi, M, Nagarajan, A, Nagel, G, Naghavi, M, Naghshtabrizi, B, Naimzada, M, Najafi, F, Nangia, V, Nansseu, J, Naserbakht, M, Nayak, V, Negoi, I, Ngunjiri, J, Nguyen, C, Nguyen, H, Nguyen, M, Nigatu, Y, Nikbakhsh, R, Nixon, M, Nnaji, C, Nomura, S, Norrving, B, Noubiap, J, Nowak, C, Nunez-Samudio, V, Oancea, B, Odell, C, Ogbo, F, Oh, I, Okunga, E, Oladnabi, M, Olagunju, A, Olusanya, B, Olusanya, J, Omer, M, Ong, K, Onwujekwe, O, Orpana, H, Ortiz, A, Osarenotor, O, Osei, F, Ostroff, S, Otoiu, A, Otstavnov, N, Otstavnov, S, Overland, S, Owolabi, M, Mahesh, P, Padubidri, J, Palladino, R, Panda-Jonas, S, Pandey, A, Parry, C, Pasovic, M, Pasupula, D, Patel, S, Pathak, M, Patten, S, Patton, G, Toroudi, H, Peden, A, Pennini, A, Pepito, V, Peprah, E, Pereira, D, Pesudovs, K, Pham, H, Phillips, M, Piccinelli, C, Pilz, T, Piradov, M, Pirsaheb, M, Plass, D, Polinder, S, Polkinghorne, K, Pond, C, Postma, M, Pourjafar, H, Pourmalek, F, Poznanska, A, Prada, S, Prakash, V, Pribadi, D, Pupillo, E, Syed, Z, Rabiee, M, Rabiee, N, Radfar, A, Rafiee, A, Raggi, A, Rahman, M, Rajabpour-Sanati, A, Rajati, F, Rakovac, I, Ram, P, Ramezanzadeh, K, Ranabhat, C, Rao, P, Rao, S, Rashedi, V, Rathi, P, Rawaf, D, Rawaf, S, Rawal, L, Rawassizadeh, R, Rawat, R, Razo, C, Redford, S, Reiner, R, Reitsma, M, Remuzzi, G, Renjith, V, Renzaho, A, Resnikoff, S, Rezaei, N, Rezapour, A, Rhinehart, P, Riahi, S, Ribeiro, D, Rickard, J, Rivera, J, Roberts, N, Rodriguez-Ramirez, S, Roever, L, Ronfani, L, Room, R, Roshandel, G, Roth, G, Rothenbacher, D, Rubagotti, E, Rwegerera, G, Sabour, S, Sachdev, P, Saddik, B, Sadeghi, E, Sadeghi, M, Saeedi, R, Saeedi Moghaddam, S, Safari, Y, Safi, S, Safiri, S, Sagar, R, Sahebkar, A, Sajadi, S, Salam, N, Salamati, P, Salem, H, Salem, M, Salimzadeh, H, Salman, O, Salomon, J, Samad, Z, Samadi Kafil, H, Sambala, E, Samy, A, Sanabria, J, Sanchez-Pimienta, T, Santomauro, D, Santos, I, Santos, J, Santric-Milicevic, M, Saraswathy, S, Sarmiento-Suarez, R, Sarrafzadegan, N, Sartorius, B, Sarveazad, A, Sathian, B, Sathish, T, Sattin, D, Saxena, S, Schaeffer, L, Schiavolin, S, Schlaich, M, Schmidt, M, Schutte, A, Schwebel, D, Schwendicke, F, Senbeta, A, Senthilkumaran, S, Sepanlou, S, Serdar, B, Serre, M, Shadid, J, Shafaat, O, Shahabi, S, Shaheen, A, Shaikh, M, Shalash, A, Shams-Beyranvand, M, Shamsizadeh, M, Sharafi, K, Sheikh, A, Sheikhtaheri, A, Shibuya, K, Shield, K, Shigematsu, M, Shin, J, Shin, M, Shiri, R, Shirkoohi, R, Shuval, K, Siabani, S, Sierpinski, R, Sigfusdottir, I, Sigurvinsdottir, R, Silva, J, Simpson, K, Singh, J, Singh, P, Skiadaresi, E, Skou, S, Skryabin, V, Smith, E, Soheili, A, Soltani, S, Soofi, M, Sorensen, R, Soriano, J, Sorrie, M, Soshnikov, S, Soyiri, I, Spencer, C, Spotin, A, Sreeramareddy, C, Srinivasan, V, Stanaway, J, Stein, C, Stein, D, Steiner, C, Stockfelt, L, Stokes, M, Straif, K, Stubbs, J, Sufiyan, M, Suleria, H, Suliankatchi Abdulkader, R, Sulo, G, Sultan, I, Tabares-Seisdedos, R, Tabb, K, Tabuchi, T, Taherkhani, A, Tajdini, M, Takahashi, K, Takala, J, Tamiru, A, Taveira, N, Tehrani-Banihashemi, A, Temsah, M, Tesema, G, Tessema, Z, Thurston, G, Titova, M, Tohidinik, H, Tonelli, M, Topor-Madry, R, Topouzis, F, Torre, A, Touvier, M, Tovani-Palone, M, Tran, B, Travillian, R, Tsatsakis, A, Tudor Car, L, Tyrovolas, S, Uddin, R, Umeokonkwo, C, Unnikrishnan, B, Upadhyay, E, Vacante, M, Valdez, P, van Donkelaar, A, Vasankari, T, Vasseghian, Y, Veisani, Y, Venketasubramanian, N, Violante, F, Vlassov, V, Vollset, S, Vos, T, Vukovic, R, Waheed, Y, Wallin, M, Wang, Y, Watson, A, Wei, J, Wei, M, Weintraub, R, Weiss, J, Werdecker, A, West, J, Westerman, R, Whisnant, J, Whiteford, H, Wiens, K, Wolfe, C, Wozniak, S, Wu, A, Wu, J, Wulf Hanson, S, Xu, G, Xu, R, Yadgir, S, Yahyazadeh Jabbari, S, Yamagishi, K, Yaminfirooz, M, Yano, Y, Yaya, S, Yazdi-Feyzabadi, V, Yeheyis, T, Yilgwan, C, Yilma, M, Yip, P, Yonemoto, N, Younis, M, Younker, T, Yousefi, B, Yousefi, Z, Yousefinezhadi, T, Yousuf, A, Yu, C, Yusefzadeh, H, Moghadam, T, Zamani, M, Zamanian, M, Zandian, H, Zastrozhin, M, Zhang, Y, Zhang, Z, Zhao, J, Zhao, X, Zhao, Y, Zheng, P, Zhou, M, Ziapour, A, Zimsen, S, Lim, S, Murray, C, Abbafati C., Abbas K. M., Abbasi-Kangevari M., Abd-Allah F., Abdelalim A., Abdollahi M., Abdollahpour I., Abegaz K. H., Abolhassani H., Aboyans V., Abreu L. G., Abrigo M. R. M., Abualhasan A., Abu-Raddad L. J., Abushouk A. I., Adabi M., Adekanmbi V., Adeoye A. M., Adetokunboh O. O., Adham D., Advani S. M., Afshin A., Agarwal G., Aghamir S. M. K., Agrawal A., Ahmad T., Ahmadi K., Ahmadi M., Ahmadieh H., Ahmed M. B., Akalu T. Y., Akinyemi R. O., Akinyemiju T., Akombi B., Akunna C. J., Alahdab F., Al-Aly Z., Alam K., Alam S., Alam T., Alanezi F. M., Alanzi T. M., Alemu B. W., Alhabib K. F., Ali M., Ali S., Alicandro G., Alinia C., Alipour V., Alizade H., Aljunid S. M., Alla F., Allebeck P., Almasi-Hashiani A., Al-Mekhlafi H. M., Alonso J., Altirkawi K. A., Amini-Rarani M., Amiri F., Amugsi D. A., Ancuceanu R., Anderlini D., Anderson J. A., Andrei C. L., Andrei T., Angus C., Anjomshoa M., Ansari F., Ansari-Moghaddam A., Antonazzo I. C., Antonio C. A. T., Antony C. M., Antriyandarti E., Anvari D., Anwer R., Appiah S. C. Y., Arabloo J., Arab-Zozani M., Aravkin A. Y., Ariani F., Armoon B., Arnlov J., Arzani A., Asadi-Aliabadi M., Asadi-Pooya A. A., Ashbaugh C., Assmus M., Atafar Z., Atnafu D. D., Atout M. M. W., Ausloos F., Ausloos M., Ayala Quintanilla B. P., Ayano G., Ayanore M. A., Azari S., Azarian G., Azene Z. N., Badawi A., Badiye A. D., Bahrami M. A., Bakhshaei M. H., Bakhtiari A., Bakkannavar S. M., Baldasseroni A., Ball K., Ballew S. H., Balzi D., Banach M., Banerjee S. K., Bante A. B., Baraki A. G., Barker-Collo S. L., Barnighausen T. W., Barrero L. H., Barthelemy C. M., Barua L., Basu S., Baune B. T., Bayati M., Becker J. S., Bedi N., Beghi E., Bejot Y., Bell M. L., Bennitt F. B., Bensenor I. M., Berhe K., Berman A. E., Bhagavathula A. S., Bhageerathy R., Bhala N., Bhandari D., Bhattacharyya K., Bhutta Z. A., Bijani A., Bikbov B., Bin Sayeed M. S. B., Biondi A., Birihane B. M., Bisignano C., Biswas R. K., Bitew H., Bohlouli S., Bohluli M., Boon-Dooley A. S., Borges G., Borzi A. M., Borzouei S., Bosetti C., Boufous S., Braithwaite D., Brauer M., Breitborde N. J. K., Breitner S., Brenner H., Briant P. S., Briko A. N., Briko N. I., Britton G. B., Bryazka D., Bumgarner B. R., Burkart K., Burnett R. T., Burugina Nagaraja S., Butt Z. A., Caetano Dos Santos F. L., Cahill L. E., Camera L. A., Campos-Nonato I. R., Cardenas R., Carreras G., Carrero J. J., Carvalho F., Castaldelli-Maia J. M., Castaneda-Orjuela C. A., Castelpietra G., Castro F., Causey K., Cederroth C. R., Cercy K. M., Cerin E., Chandan J. S., Chang K. -L., Charlson F. J., Chattu V. K., Chaturvedi S., Cherbuin N., Chimed-Ochir O., Cho D. Y., Choi J. -Y. J., Christensen H., Chu D. -T., Chung M. T., Chung S. -C., Cicuttini F. M., Ciobanu L. G., Cirillo M., Classen T. K. D., Cohen A. J., Compton K., Cooper O. R., Costa V. M., Cousin E., Cowden R. G., Cross D. H., Cruz J. A., Dahlawi S. M. A., Damasceno A. A. M., Damiani G., Dandona L., Dandona R., Dangel W. J., Danielsson A. -K., Dargan P. I., Darwesh A. M., Daryani A., Das J. K., Das Gupta R., das Neves J., Davila-Cervantes C. A., Davitoiu D. V., De Leo D., Degenhardt L., DeLang M., Dellavalle R. P., Demeke F. M., Demoz G. T., Demsie D. G., Denova-Gutierrez E., Dervenis N., Dhungana G. P., Dianatinasab M., Dias da Silva D., Diaz D., Dibaji Forooshani Z. S., Djalalinia S., Do H. T., Dokova K., Dorostkar F., Doshmangir L., Driscoll T. R., Duncan B. B., Duraes A. R., Eagan A. W., Edvardsson D., El Nahas N., El Sayed I., El Tantawi M., Elbarazi I., Elgendy I. Y., El-Jaafary S. I., Elyazar I. R. F., Emmons-Bell S., Erskine H. E., Eskandarieh S., Esmaeilnejad S., Esteghamati A., Estep K., Etemadi A., Etisso A. E., Fanzo J., Farahmand M., Fareed M., Faridnia R., Farioli A., Faro A., Faruque M., Farzadfar F., Fattahi N., Fazlzadeh M., Feigin V. L., Feldman R., Fereshtehnejad S. -M., Fernandes E., Ferrara G., Ferrari A. J., Ferreira M. L., Filip I., Fischer F., Fisher J. L., Flor L. S., Foigt N. A., Folayan M. O., Fomenkov A. A., Force L. M., Foroutan M., Franklin R. C., Freitas M., Fu W., Fukumoto T., Furtado J. M., Gad M. M., Gakidou E., Gallus S., Garcia-Basteiro A. L., Gardner W. M., Geberemariyam B. S., Ayalew Gebreslassie A. A. A., Geremew A., Gershberg Hayoon A., Gething P. W., Ghadimi M., Ghadiri K., Ghaffarifar F., Ghafourifard M., Ghamari F., Ghashghaee A., Ghiasvand H., Ghith N., Gholamian A., Ghosh R., Gill P. S., Ginindza T. G., Giussani G., Gnedovskaya E. V., Goharinezhad S., Gopalani S. V., Gorini G., Goudarzi H., Goulart A. C., Greaves F., Grivna M., Grosso G., Gubari M. I. M., Gugnani H. C., Guimaraes R. A., Guled R. A., Guo G., Guo Y., Gupta R., Gupta T., Haddock B., Hafezi-Nejad N., Hafiz A., Haj-Mirzaian A., Hall B. J., Halvaei I., Hamadeh R. R., Hamidi S., Hammer M. S., Hankey G. J., Haririan H., Haro J. M., Hasaballah A. I., Hasan M. M., Hasanpoor E., Hashi A., Hassanipour S., Hassankhani H., Havmoeller R. J., Hay S. I., Hayat K., Heidari G., Heidari-Soureshjani R., Henrikson H. J., Herbert M. E., Herteliu C., Heydarpour F., Hird T. R., Hoek H. W., Holla R., Hoogar P., Hosgood H. D., Hossain N., Hosseini M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Househ M., Hsairi M., Hsieh V. C. -R., Hu G., Hu K., Huda T. M., Humayun A., Huynh C. K., Hwang B. -F., Iannucci V. C., Ibitoye S. E., Ikeda N., Ikuta K. S., Ilesanmi O. S., Ilic I. M., Ilic M. D., Inbaraj L. R., Ippolito H., Iqbal U., Irvani S. S. N., Irvine C. M. S., Islam M. M., Islam S. M. S., Iso H., Ivers R. Q., Iwu C. C. D., Iwu C. J., Iyamu I. O., Jaafari J., Jacobsen K. H., Jafari H., Jafarinia M., Jahani M. A., Jakovljevic M., Jalilian F., James S. L., Janjani H., Javaheri T., Javidnia J., Jeemon P., Jenabi E., Jha R. P., Jha V., Ji J. S., Johansson L., John O., John-Akinola Y. O., Johnson C. O., Jonas J. B., Joukar F., Jozwiak J. 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P., Yousefi B., Yousefi Z., Yousefinezhadi T., Yousuf A. Y., Yu C., Yusefzadeh H., Moghadam T. Z., Zamani M., Zamanian M., Zandian H., Zastrozhin M. S., Zhang Y., Zhang Z. -J., Zhao J. T., Zhao X. -J. G., Zhao Y., Zheng P., Zhou M., Ziapour A., Zimsen S. R. M., Lim S. S., and Murray C. J. L.
Abstract: Background: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attributable burden of disease. Methods: GBD 2019 estimated attributable mortality, years of life lost (YLLs), years of life lived with disability (YLDs), and disability-adjusted life-years (DALYs) for 87 risk factors and combinations of risk factors, at the global level, regionally, and for 204 countries and territories. GBD uses a hierarchical list of risk factors so that specific risk factors (eg, sodium intake), and related aggregates (eg, diet quality), are both evaluated. This method has six analytical steps. (1) We included 560 risk–outcome pairs that met criteria for convincing or probable evidence on the basis of research studies. 12 risk–outcome pairs included in GBD 2017 no longer met inclusion criteria and 47 risk–outcome pairs for risks already included in GBD 2017 were added based on new evidence. (2) Relative risks were estimated as a function of exposure based on published systematic reviews, 81 systematic reviews done for GBD 2019, and meta-regression. (3) Levels of exposure in each age-sex-location-year included in the study were estimated based on all available data sources using spatiotemporal Gaussian process regression, DisMod-MR 2.1, a Bayesian meta-regression method, or alternative methods. (4) We determined, from published trials or cohort studies, the level of exposure associated with minimum risk, called the theoretical minimum risk exposure level. (5) Attributable deaths, YLLs, YLDs, and DALYs were computed by multiplying population attributable fractions (PAFs) by the relevant outcome quantity for each
Published: 2020

7. Mapping routine measles vaccination in low- and middle-income countries.

Author: Sambala E.Z., Waheed Y., Wakefield J., Wang Y., Wang Y.-P., Weldesamuel G.T., Werdecker A., Westerman R., Wiangkham T., Wiens K.E., Wiysonge C.S., Woldu G., Wondafrash D.Z., Wonde T.E., Wu A.-M., Yadollahpour A., Jabbari S.H.Y., Yamada T., Yaya S., Yazdi-Feyzabadi V., Yeheyis T.Y., Yeshaw Y., Yilgwan C.S., Yip P., Yonemoto N., Younis M.Z., Yousefi Z., Yousefifard M., Yousefinezhadi T., Yu C., Yusefzadeh H., Zadey S., Zahirian Moghadam T., Zaki L., Zaman S.B., Zamani M., Zamanian M., Zandian H., Zangeneh A., Zarei F., Zerfu T.A., Zhang Y., Zhang Z.-J., Zhao X.-J.G., Zhou M., Ziapour A., Hay S.I., Lim S.S., Mosser J.F., Biswas A., Sbarra A.N., Rolfe S., Nguyen J.Q., Earl L., Galles N.C., Marks A., Abbas K.M., Abbasi-Kangevari M., Abbastabar H., Abd-Allah F., Abdelalim A., Abdollahi M., Abegaz K.H., Abiy H.A.A., Abolhassani H., Abreu L.G., Abrigo M.R.M., Abushouk A.I., Accrombessi M.M.K., Adabi M., Adebayo O.M., Adekanmbi V., Adetokunboh O.O., Adham D., Afarideh M., Aghaali M., Ahmad T., Ahmadi R., Ahmadi K., Ahmed M.B., Alanezi F.M., Alanzi T.M., Alcalde-Rabanal J.E., Alemnew B.T., Ali B.A., Ali M., Alijanzadeh M., Alinia C., Alipoor R., Alipour V., Alizade H., Aljunid S.M., Almasi A., Almasi-Hashiani A., Al-Mekhlafi H.M., Altirkawi K.A., Amare B., Amini S., Amini-Rarani M., Amiri F., Amit A.M.L., Amugsi D.A., Ancuceanu R., Andrei C.L., Anjomshoa M., Ansari F., Ansari-Moghaddam A., Ansha M.G., Antonio C.A.T., Antriyandarti E., Anvari D., Arabloo J., Arab-Zozani M., Aremu O., Armoon B., Aryal K.K., Arzani A., Asadi-Aliabadi M., Asgari S., Atafar Z., Ausloos M., Awoke N., Quintanilla B.P.A., Ayanore M.A., Aynalem Y.A., Azadmehr A., Azari S., Babaee E., Badawi A., Badiye A.D., Bahrami M.A., Baig A.A., Bakhtiari A., Balakrishnan S., Banach M., Banik P.C., Barac A., Baradaran-Seyed Z., Baraki A.G., Basu S., Bayati M., Bayou Y.T., Bedi N., Behzadifar M., Bell M.L., Berbada D.A., Berhe K., Bhattarai S., Bhutta Z.A., Bijani A., Birhanu M., Bisanzio D., Bohlouli S., Bolla S.R., Borzouei S., Brady O.J., Bragazzi N.L., Briko A.N., Briko N.I., Nagaraja S.B., Butt Z.A., Camera L.A., Campos-Nonato I.R., Car J., Cardenas R., Carvalho F., Castaldelli-Maia J.M., Castro F., Chattu V.K., Chehrazi M., Chin K.L., Chu D.-T., Cook A.J., Cormier N.M., Cunningham B., Dahlawi S.M.A., Damiani G., Dandona R., Dandona L., Danovaro M.C., Dansereau E., Daoud F., Darwesh A.M., Darwish A.H., Das J.K., Weaver N.D., De Neve J.-W., Demeke F.M., Demis A.B., Denova-Gutierrez E., Desalew A., Deshpande A., Desta D.M., Dharmaratne S.D., Dhungana G.P., Dianatinasab M., Diaz D., Dipeolu I.O., Djalalinia S., Do H.T., Dorostkar F., Doshmangir L., Doyle K.E., Dunachie S.J., Duraes A.R., Kalan M.E., Leylabadlo H.E., Edinur H.A., Effiong A., Eftekhari A., El Sayed I., El Sayed Zaki M., Elema T.B., Elhabashy H.R., El-Jaafary S.I., Elsharkawy A., Emamian M.H., Enany S., Eshrati B., Eskandari K., Eskandarieh S., Esmaeilnejad S., Esmaeilzadeh F., Esteghamati A., Etisso A.E., Farahmand M., Faraon E.J.A., Fareed M., Faridnia R., Farioli A., Farzadfar F., Fattahi N., Fazlzadeh M., Fereshtehnejad S.-M., Fernandes E., Filip I., Fischer F., Foigt N.A., Folayan M.O., Foroutan M., Fukumoto T., Fullman N., Gad M.M., Geberemariyam B.S., Gebrehiwot T.T., Gebrehiwot A.M., Gebremariam K.T., Gebremedhin K.B., Gebremeskel G.G., Gebreslassie A.A., Gedefaw G.A., Gezae K.E., Ghadiri K., Ghaffari R., Ghaffarifar F., Ghajarzadeh M., Gheshlagh R.G., Ghashghaee A., Ghiasvand H., Gholamian A., Gilani S.A., Gill P.S., Girmay A., Gomes N.G.M., Gopalani S.V., Goulart B.N.G., Grada A., Guimaraes R.A., Guo Y., Gupta R., Hafezi-Nejad N., Haj-Mirzaian A., Handiso D.W., Hanif A., Haririan H., Hasaballah A.I., Hasan M.M., Hasanpoor E., Hasanzadeh A., Hassanipour S., Hassankhani H., Heidari-Soureshjani R., Henry N.J., Herteliu C., Heydarpour F., Hollerich G.I., Rad E.H., Hoogar P., Hossain N., Hosseini M., Hosseinzadeh M., Househ M., Hu G., Huda T.M., Humayun A., Ibitoye S.E., Ikilezi G., Ilesanmi O.S., Ilic I.M., Ilic M.D., Imani-Nasab M.H., Inbaraj L.R., Iqbal U., Irvani S.S.N., Islam S.M.S., Islam M.M., Iwu C.J., Iwu C.C.D., Jadidi-Niaragh F., Jafarinia M., Jahanmehr N., Jakovljevic M., Jalali A., Jalilian F., Javidnia J., Jenabi E., Jha V., Ji J.S., John O., Johnson K.B., Joukar F., Jozwiak J.J., Kabir Z., Kabir A., Kalani H., Kalankesh L.R., Kalhor R., Kamal Z., Kanchan T., Kapoor N., Karami M., Matin B.K., Karch A., Karimi S.E., Kayode G.A., Karyani A.K., Keiyoro P.N., Khader Y.S., Khafaie M.A., Khammarnia M., Khan M.S., Khan E.A., Khan J., Khan M.N., Khatab K., Khater M.M., Khatib M.N., Khayamzadeh M., Khazaei M., Khazaei S., Khosravi A., Khubchandani J., Kianipour N., Kim Y.J., Kimokoti R.W., Kinyoki D.K., Kisa A., Kisa S., Kolola T., Komaki H., Kosen S., Koul P.A., Koyanagi A., Kraemer M.U.G., Krishan K., Kuate Defo B., Kumar M., Kumar P., Kumar G.A., Kusuma D., La Vecchia C., Lacey B., Lad S.D., Lal D.K., Lam F., Lami F.H., Lansingh V.C., Larson H.J., Lasrado S., Lee S.W.H., Lee P.H., LeGrand K.E., Lenjebo T.L., Li S., Liang X., Liu P.Y., Lopukhov P.D., Machado D.B., Mahasha P.W., Mahdavi M.M., Maheri M., Mahotra N.B., Maled V., Maleki S., Malik M.A., Malta D.C., Mansour-Ghanaei F., Mansouri B., Mansourian M., Mansournia M.A., Martins-Melo F.R., Masaka A., Mayala B.K., Mehndiratta M.M., Mehri F., Mehta K.M., Memiah P.T.N., Mendoza W., Menezes R.G., Mengesha M.B., Mengesha E.W., Mestrovic T., Mihretie K.M., Miller-Petrie M.K., Mills E.J., Milne G.J., Mirabi P., Mirrakhimov E.M., Mirzaei R., Mirzaei M., Mirzaei H.R., Mirzaei H., Mirzaei-Alavijeh M., Moazen B., Moghadaszadeh M., Mohamadi E., Mohammad D.K., Mohammad Y., Mohammad K.A., Mohammad Gholi Mezerji N., Mohammadbeigi A., Mohammadian-Hafshejani A., Mohammadpourhodki R., Mohammed S., Mohammed A.S., Mohammed H., Mohebi F., Mokdad A.H., Monasta L., Moosavi M.A., Moosazadeh M., Moradi G., Moradi M., Moradi-Joo M., Moradi-Lakeh M., Moradzadeh R., Moraga P., Mosapour A., Mouodi S., Mousavi S.M., Khaneghah A.M., Mueller U.O., Muluneh A.G., Munro S.B., Murray C.J.L., Murthy G.V.S., Muthupandian S., Naderi M., Nagarajan A.J., Naghavi M., Nangia V., Nansseu J.R., Nayak V.C., Nazari J., Ndwandwe D.E., Negoi I., Ngunjiri J.W., Nguyen H.L.T., Nguyen C.T.K., Nguyen T.H., Nigatu Y.T., Nikbakhsh R., Nikfar S., Nikpoor A.R., Ningrum D.N.A., Nnaji C.A., Oh I.-H., Oladnabi M., Olagunju A.T., Olusanya J.O., Olusanya B.O., Bali A.O., Omer M.O., Onwujekwe O.E., Osgood-Zimmerman A.E., Owolabi M.O., P A M., Padubidri J.R., Pakshir K., Pana A., Pandey A., Pando-Robles V., Pashaei T., Pasupula D.K., Paternina-Caicedo A.J., Patton G.C., Pazoki Toroudi H., Pepito V.C.F., Pescarini J.M., Pigott D.M., Pilgrim T., Pirsaheb M., Poljak M., Postma M.J., Pourjafar H., Pourmalek F., Pourmirza Kalhori R., Prada S.I., Prakash S., Quazi Syed Z., Quintana H., Rabiee N., Rabiee M., Radfar A., Rafiei A., Rahim F., Rajati F., Rameto M.A., Ramezanzadeh K., Ranabhat C.L., Rao S.J., Rasella D., Rastogi P., Rathi P., Rawaf S., Rawaf D.L., Rawal L., Rawassizadeh R., Rawat R., Renjith V., Renzaho A.M.N., Reshmi B., Reta M.A., Rezaei N., Rezai M.S., Rezapour A., Riahi S.M., Ribeiro A.I., Rickard J., Rios-Blancas M., Rios-Gonzalez C.M., Roever L., Rostamian M., Rubino S., Rwegerera G.M., Saad A.M., Saadatagah S., Sabour S., Sadeghi E., Moghaddam S.S., Saeidi S., Sagar R., Sahebkar A., Sahraian M.A., Sajadi S.M., Salahshoor M.R., Salam N., Salem H., Salem M.R., Salomon J.A., Kafil H.S., Samy A.M., Saraswathy S.Y.I., Sarmiento-Suarez R., Saroshe S., Sartorius B., Sarveazad A., Sathian B., Sathish T., Schaeffer L.E., Schwebel D.C., Senthilkumaran S., Shabaninejad H., Shahabi S., Shaheen A.A., Shaikh M.A., Shalash A.S., Shams-Beyranvand M., Shamsi M.B., Shamsizadeh M., Sharafi K., Sharifi H., Sheikh A., Sheikhtaheri A., Shetty R.S., Shiferaw W.S., Shigematsu M., Shin J.I., Shirkoohi R., Siabani S., Siddiqi T.J., Silverberg J.I.S., Simonetti B., Singh J.A., Sinha D.N., Sinke A.H., Soheili A., Sokhan A., Soltani S., Soofi M., Sorrie M.B., Soyiri I.N., Spotin A., Spurlock E.E., Sreeramareddy C.T., Sudaryanto A., Sufiyan M.B., Suleria H.A.R., Abdulkader R.S., Taherkhani A., Tapak L., Taveira N., Taymoori P., Tefera Y.M., Tehrani-Banihashemi A., Teklehaimanot B.F., Tekulu G.H., Tesfay B.E., Tessema Z.T., Tessema B., Thankappan K.R., Tohidinik H.R., Topor-Madry R., Tovani-Palone M.R., Tran B.X., Uddin R., Ullah I., Umeokonkwo C.D., Unnikrishnan B., Upadhyay E., Usman M.S., Vaezi M., Valadan Tahbaz S., Valdez P.R., Vasseghian Y., Veisani Y., Violante F.S., Vollmer S., Sambala E.Z., Waheed Y., Wakefield J., Wang Y., Wang Y.-P., Weldesamuel G.T., Werdecker A., Westerman R., Wiangkham T., Wiens K.E., Wiysonge C.S., Woldu G., Wondafrash D.Z., Wonde T.E., Wu A.-M., Yadollahpour A., Jabbari S.H.Y., Yamada T., Yaya S., Yazdi-Feyzabadi V., Yeheyis T.Y., Yeshaw Y., Yilgwan C.S., Yip P., Yonemoto N., Younis M.Z., Yousefi Z., Yousefifard M., Yousefinezhadi T., Yu C., Yusefzadeh H., Zadey S., Zahirian Moghadam T., Zaki L., Zaman S.B., Zamani M., Zamanian M., Zandian H., Zangeneh A., Zarei F., Zerfu T.A., Zhang Y., Zhang Z.-J., Zhao X.-J.G., Zhou M., Ziapour A., Hay S.I., Lim S.S., Mosser J.F., Biswas A., Sbarra A.N., Rolfe S., Nguyen J.Q., Earl L., Galles N.C., Marks A., Abbas K.M., Abbasi-Kangevari M., Abbastabar H., Abd-Allah F., Abdelalim A., Abdollahi M., Abegaz K.H., Abiy H.A.A., Abolhassani H., Abreu L.G., Abrigo M.R.M., Abushouk A.I., Accrombessi M.M.K., Adabi M., Adebayo O.M., Adekanmbi V., Adetokunboh O.O., Adham D., Afarideh M., Aghaali M., Ahmad T., Ahmadi R., Ahmadi K., Ahmed M.B., Alanezi F.M., Alanzi T.M., Alcalde-Rabanal J.E., Alemnew B.T., Ali B.A., Ali M., Alijanzadeh M., Alinia C., Alipoor R., Alipour V., Alizade H., Aljunid S.M., Almasi A., Almasi-Hashiani A., Al-Mekhlafi H.M., Altirkawi K.A., Amare B., Amini S., Amini-Rarani M., Amiri F., Amit A.M.L., Amugsi D.A., Ancuceanu R., Andrei C.L., Anjomshoa M., Ansari F., Ansari-Moghaddam A., Ansha M.G., Antonio C.A.T., Antriyandarti E., Anvari D., Arabloo J., Arab-Zozani M., Aremu O., Armoon B., Aryal K.K., Arzani A., Asadi-Aliabadi M., Asgari S., Atafar Z., Ausloos M., Awoke N., Quintanilla B.P.A., Ayanore M.A., Aynalem Y.A., Azadmehr A., Azari S., Babaee E., Badawi A., Badiye A.D., Bahrami M.A., Baig A.A., Bakhtiari A., Balakrishnan S., Banach M., Banik P.C., Barac A., Baradaran-Seyed Z., Baraki A.G., Basu S., Bayati M., Bayou Y.T., Bedi N., Behzadifar M., Bell M.L., Berbada D.A., Berhe K., Bhattarai S., Bhutta Z.A., Bijani A., Birhanu M., Bisanzio D., Bohlouli S., Bolla S.R., Borzouei S., Brady O.J., Bragazzi N.L., Briko A.N., Briko N.I., Nagaraja S.B., Butt Z.A., Camera L.A., Campos-Nonato I.R., Car J., Cardenas R., Carvalho F., Castaldelli-Maia J.M., Castro F., Chattu V.K., Chehrazi M., Chin K.L., Chu D.-T., Cook A.J., Cormier N.M., Cunningham B., Dahlawi S.M.A., Damiani G., Dandona R., Dandona L., Danovaro M.C., Dansereau E., Daoud F., Darwesh A.M., Darwish A.H., Das J.K., Weaver N.D., De Neve J.-W., Demeke F.M., Demis A.B., Denova-Gutierrez E., Desalew A., Deshpande A., Desta D.M., Dharmaratne S.D., Dhungana G.P., Dianatinasab M., Diaz D., Dipeolu I.O., Djalalinia S., Do H.T., Dorostkar F., Doshmangir L., Doyle K.E., Dunachie S.J., Duraes A.R., Kalan M.E., Leylabadlo H.E., Edinur H.A., Effiong A., Eftekhari A., El Sayed I., El Sayed Zaki M., Elema T.B., Elhabashy H.R., El-Jaafary S.I., Elsharkawy A., Emamian M.H., Enany S., Eshrati B., Eskandari K., Eskandarieh S., Esmaeilnejad S., Esmaeilzadeh F., Esteghamati A., Etisso A.E., Farahmand M., Faraon E.J.A., Fareed M., Faridnia R., Farioli A., Farzadfar F., Fattahi N., Fazlzadeh M., Fereshtehnejad S.-M., Fernandes E., Filip I., Fischer F., Foigt N.A., Folayan M.O., Foroutan M., Fukumoto T., Fullman N., Gad M.M., Geberemariyam B.S., Gebrehiwot T.T., Gebrehiwot A.M., Gebremariam K.T., Gebremedhin K.B., Gebremeskel G.G., Gebreslassie A.A., Gedefaw G.A., Gezae K.E., Ghadiri K., Ghaffari R., Ghaffarifar F., Ghajarzadeh M., Gheshlagh R.G., Ghashghaee A., Ghiasvand H., Gholamian A., Gilani S.A., Gill P.S., Girmay A., Gomes N.G.M., Gopalani S.V., Goulart B.N.G., Grada A., Guimaraes R.A., Guo Y., Gupta R., Hafezi-Nejad N., Haj-Mirzaian A., Handiso D.W., Hanif A., Haririan H., Hasaballah A.I., Hasan M.M., Hasanpoor E., Hasanzadeh A., Hassanipour S., Hassankhani H., Heidari-Soureshjani R., Henry N.J., Herteliu C., Heydarpour F., Hollerich G.I., Rad E.H., Hoogar P., Hossain N., Hosseini M., Hosseinzadeh M., Househ M., Hu G., Huda T.M., Humayun A., Ibitoye S.E., Ikilezi G., Ilesanmi O.S., Ilic I.M., Ilic M.D., Imani-Nasab M.H., Inbaraj L.R., Iqbal U., Irvani S.S.N., Islam S.M.S., Islam M.M., Iwu C.J., Iwu C.C.D., Jadidi-Niaragh F., Jafarinia M., Jahanmehr N., Jakovljevic M., Jalali A., Jalilian F., Javidnia J., Jenabi E., Jha V., Ji J.S., John O., Johnson K.B., Joukar F., Jozwiak J.J., Kabir Z., Kabir A., Kalani H., Kalankesh L.R., Kalhor R., Kamal Z., Kanchan T., Kapoor N., Karami M., Matin B.K., Karch A., Karimi S.E., Kayode G.A., Karyani A.K., Keiyoro P.N., Khader Y.S., Khafaie M.A., Khammarnia M., Khan M.S., Khan E.A., Khan J., Khan M.N., Khatab K., Khater M.M., Khatib M.N., Khayamzadeh M., Khazaei M., Khazaei S., Khosravi A., Khubchandani J., Kianipour N., Kim Y.J., Kimokoti R.W., Kinyoki D.K., Kisa A., Kisa S., Kolola T., Komaki H., Kosen S., Koul P.A., Koyanagi A., Kraemer M.U.G., Krishan K., Kuate Defo B., Kumar M., Kumar P., Kumar G.A., Kusuma D., La Vecchia C., Lacey B., Lad S.D., Lal D.K., Lam F., Lami F.H., Lansingh V.C., Larson H.J., Lasrado S., Lee S.W.H., Lee P.H., LeGrand K.E., Lenjebo T.L., Li S., Liang X., Liu P.Y., Lopukhov P.D., Machado D.B., Mahasha P.W., Mahdavi M.M., Maheri M., Mahotra N.B., Maled V., Maleki S., Malik M.A., Malta D.C., Mansour-Ghanaei F., Mansouri B., Mansourian M., Mansournia M.A., Martins-Melo F.R., Masaka A., Mayala B.K., Mehndiratta M.M., Mehri F., Mehta K.M., Memiah P.T.N., Mendoza W., Menezes R.G., Mengesha M.B., Mengesha E.W., Mestrovic T., Mihretie K.M., Miller-Petrie M.K., Mills E.J., Milne G.J., Mirabi P., Mirrakhimov E.M., Mirzaei R., Mirzaei M., Mirzaei H.R., Mirzaei H., Mirzaei-Alavijeh M., Moazen B., Moghadaszadeh M., Mohamadi E., Mohammad D.K., Mohammad Y., Mohammad K.A., Mohammad Gholi Mezerji N., Mohammadbeigi A., Mohammadian-Hafshejani A., Mohammadpourhodki R., Mohammed S., Mohammed A.S., Mohammed H., Mohebi F., Mokdad A.H., Monasta L., Moosavi M.A., Moosazadeh M., Moradi G., Moradi M., Moradi-Joo M., Moradi-Lakeh M., Moradzadeh R., Moraga P., Mosapour A., Mouodi S., Mousavi S.M., Khaneghah A.M., Mueller U.O., Muluneh A.G., Munro S.B., Murray C.J.L., Murthy G.V.S., Muthupandian S., Naderi M., Nagarajan A.J., Naghavi M., Nangia V., Nansseu J.R., Nayak V.C., Nazari J., Ndwandwe D.E., Negoi I., Ngunjiri J.W., Nguyen H.L.T., Nguyen C.T.K., Nguyen T.H., Nigatu Y.T., Nikbakhsh R., Nikfar S., Nikpoor A.R., Ningrum D.N.A., Nnaji C.A., Oh I.-H., Oladnabi M., Olagunju A.T., Olusanya J.O., Olusanya B.O., Bali A.O., Omer M.O., Onwujekwe O.E., Osgood-Zimmerman A.E., Owolabi M.O., P A M., Padubidri J.R., Pakshir K., Pana A., Pandey A., Pando-Robles V., Pashaei T., Pasupula D.K., Paternina-Caicedo A.J., Patton G.C., Pazoki Toroudi H., Pepito V.C.F., Pescarini J.M., Pigott D.M., Pilgrim T., Pirsaheb M., Poljak M., Postma M.J., Pourjafar H., Pourmalek F., Pourmirza Kalhori R., Prada S.I., Prakash S., Quazi Syed Z., Quintana H., Rabiee N., Rabiee M., Radfar A., Rafiei A., Rahim F., Rajati F., Rameto M.A., Ramezanzadeh K., Ranabhat C.L., Rao S.J., Rasella D., Rastogi P., Rathi P., Rawaf S., Rawaf D.L., Rawal L., Rawassizadeh R., Rawat R., Renjith V., Renzaho A.M.N., Reshmi B., Reta M.A., Rezaei N., Rezai M.S., Rezapour A., Riahi S.M., Ribeiro A.I., Rickard J., Rios-Blancas M., Rios-Gonzalez C.M., Roever L., Rostamian M., Rubino S., Rwegerera G.M., Saad A.M., Saadatagah S., Sabour S., Sadeghi E., Moghaddam S.S., Saeidi S., Sagar R., Sahebkar A., Sahraian M.A., Sajadi S.M., Salahshoor M.R., Salam N., Salem H., Salem M.R., Salomon J.A., Kafil H.S., Samy A.M., Saraswathy S.Y.I., Sarmiento-Suarez R., Saroshe S., Sartorius B., Sarveazad A., Sathian B., Sathish T., Schaeffer L.E., Schwebel D.C., Senthilkumaran S., Shabaninejad H., Shahabi S., Shaheen A.A., Shaikh M.A., Shalash A.S., Shams-Beyranvand M., Shamsi M.B., Shamsizadeh M., Sharafi K., Sharifi H., Sheikh A., Sheikhtaheri A., Shetty R.S., Shiferaw W.S., Shigematsu M., Shin J.I., Shirkoohi R., Siabani S., Siddiqi T.J., Silverberg J.I.S., Simonetti B., Singh J.A., Sinha D.N., Sinke A.H., Soheili A., Sokhan A., Soltani S., Soofi M., Sorrie M.B., Soyiri I.N., Spotin A., Spurlock E.E., Sreeramareddy C.T., Sudaryanto A., Sufiyan M.B., Suleria H.A.R., Abdulkader R.S., Taherkhani A., Tapak L., Taveira N., Taymoori P., Tefera Y.M., Tehrani-Banihashemi A., Teklehaimanot B.F., Tekulu G.H., Tesfay B.E., Tessema Z.T., Tessema B., Thankappan K.R., Tohidinik H.R., Topor-Madry R., Tovani-Palone M.R., Tran B.X., Uddin R., Ullah I., Umeokonkwo C.D., Unnikrishnan B., Upadhyay E., Usman M.S., Vaezi M., Valadan Tahbaz S., Valdez P.R., Vasseghian Y., Veisani Y., Violante F.S., and Vollmer S.
Abstract: The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)1-4. Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)5-8. Here we generated annual estimates of routine childhood MCV1 coverage at 5 x 5-km2 pixel and second administrative levels from 2000 to 2019 in 101 LMICs, quantified geographical inequality and assessed vaccination status by geographical remoteness. After widespread MCV1 gains from 2000 to 2010, coverage regressed in more than half of the districts between 2010 and 2019, leaving many LMICs far from the GVAP goal of 80% coverage in all districts by 2019. MCV1 coverage was lower in rural than in urban locations, although a larger proportion of unvaccinated children overall lived in urban locations; strategies to provide essential vaccination services should address both geographical contexts. These results provide a tool for decision-makers to strengthen routine MCV1 immunization programmes and provide equitable disease protection for all children.Copyright © 2020, The Author(s).
Published: 2021

8. Mapping routine measles vaccination in low- and middle-income countries

Author: Sbarra, AN, Rolfe, S, Nguyen, JQ, Earl, L, Galles, NC, Marks, A, Abbas, KM, Abbasi-Kangevari, M, Abbastabar, H, Abd-Allah, F, Abdelalim, A, Abdollahi, M, Abegaz, KH, Abiy, HAA, Abolhassani, H, Abreu, LG, Abrigo, MRM, Abushouk, AI, Accrombessi, MMK, Adabi, M, Adebayo, OM, Adekanmbi, V, Adetokunboh, OO, Adham, D, Afarideh, M, Aghaali, M, Ahmad, T, Ahmadi, R, Ahmadi, K, Ahmed, MB, Alanezi, FM, Alanzi, TM, Alcalde-Rabanal, JE, Alemnew, BT, Ali, BA, Ali, M, Alijanzadeh, M, Alinia, C, Alipoor, R, Alipour, V, Alizade, H, Aljunid, SM, Almasi, A, Almasi-Hashiani, A, Al-Mekhlafi, HM, Altirkawi, KA, Amare, B, Amini, S, Amini-Rarani, M, Amiri, F, Amit, AML, Amugsi, DA, Ancuceanu, R, Andrei, CL, Anjomshoa, M, Ansari, F, Ansari-Moghaddam, A, Ansha, MG, Antonio, CAT, Antriyandarti, E, Anvari, D, Arabloo, J, Arab-Zozani, M, Aremu, O, Armoon, B, Aryal, KK, Arzani, A, Asadi-Aliabadi, M, Asgari, S, Atafar, Z, Ausloos, M, Awoke, N, Quintanilla, BPA, Ayanore, MA, Aynalem, YA, Azadmehr, A, Azari, S, Babaee, E, Badawi, A, Badiye, AD, Bahrami, MA, Baig, AA, Bakhtiari, A, Balakrishnan, S, Banach, M, Banik, PC, Barac, A, Baradaran-Seyed, Z, Baraki, AG, Basu, S, Bayati, M, Bayou, YT, Bedi, N, Behzadifar, M, Bell, ML, Berbada, DA, Berhe, K, Bhattarai, S, Bhutta, ZA, Bijani, A, Birhanu, M, Bisanzio, D, Biswas, A, Bohlouli, S, Bolla, SR, Borzouei, S, Brady, OJ, Bragazzi, NL, Briko, AN, Briko, NI, Nagaraja, SB, Butt, ZA, Cámera, LA, Campos-Nonato, IR, Car, J, Cárdenas, R, Carvalho, F, Castaldelli-Maia, JM, Castro, F, Chattu, VK, Chehrazi, M, Chin, KL, Chu, D-T, Cook, AJ, Cormier, NM, Cunningham, B, Dahlawi, SMA, Damiani, G, Dandona, R, Dandona, L, Danovaro, MC, Dansereau, E, Daoud, F, Darwesh, AM, Darwish, AH, Das, JK, Weaver, ND, De Neve, J-W, Demeke, FM, Demis, AB, Denova-Gutiérrez, E, Desalew, A, Deshpande, A, Desta, DM, Dharmaratne, SD, Dhungana, GP, Dianatinasab, M, Diaz, D, Dipeolu, IO, Djalalinia, S, Do, HT, Dorostkar, F, Doshmangir, L, Doyle, KE, Dunachie, SJ, Duraes, AR, Kalan, ME, Leylabadlo, HE, Edinur, HA, Effiong, A, Eftekhari, A, El, Sayed, I, El, Sayed, Zaki, M, Elema, TB, Elhabashy, HR, El-Jaafary, SI, Elsharkawy, A, Emamian, MH, Enany, S, Eshrati, B, Eskandari, K, Eskandarieh, S, Esmaeilnejad, S, Esmaeilzadeh, F, Esteghamati, A, Etisso, AE, Farahmand, M, Faraon, EJA, Fareed, M, Faridnia, R, Farioli, A, Farzadfar, F, Fattahi, N, Fazlzadeh, M, Fereshtehnejad, S-M, Fernandes, E, Filip, I, Fischer, F, Foigt, NA, Folayan, MO, Foroutan, M, Fukumoto, T, Fullman, N, Gad, MM, Geberemariyam, BS, Gebrehiwot, TT, Gebrehiwot, AM, Gebremariam, KT, Gebremedhin, KB, Gebremeskel, GG, Gebreslassie, AA, Gedefaw, GA, Gezae, KE, Ghadiri, K, Ghaffari, R, Ghaffarifar, F, Ghajarzadeh, M, Gheshlagh, RG, Ghashghaee, A, Ghiasvand, H, Gholamian, A, Gilani, SA, Gill, PS, Girmay, A, Gomes, NGM, Gopalani, SV, Goulart, BNG, Grada, A, Guimarães, RA, Guo, Y, Gupta, R, Hafezi-Nejad, N, Haj-Mirzaian, A, Handiso, DW, Hanif, A, Haririan, H, Hasaballah, AI, Hasan, MM, Hasanpoor, E, Hasanzadeh, A, Hassanipour, S, Hassankhani, H, Heidari-Soureshjani, R, Henry, NJ, Herteliu, C, Heydarpour, F, Hollerich, GI, Rad, EH, Hoogar, P, Hossain, N, Hosseini, M, Hosseinzadeh, M, Househ, M, Hu, G, Huda, TM, Humayun, A, Ibitoye, SE, Ikilezi, G, Ilesanmi, OS, Ilic, IM, Ilic, MD, Imani-Nasab, MH, Inbaraj, LR, Iqbal, U, Irvani, SSN, Islam, SMS, Islam, MM, Iwu, CJ, Iwu, CCD, Jadidi-Niaragh, F, Jafarinia, M, Jahanmehr, N, Jakovljevic, M, Jalali, A, Jalilian, F, Javidnia, J, Jenabi, E, Jha, V, Ji, JS, John, O, Johnson, KB, Joukar, F, Jozwiak, JJ, Kabir, Z, Kabir, A, Kalani, H, Kalankesh, LR, Kalhor, R, Kamal, Z, Kanchan, T, Kapoor, N, Karami, M, Matin, BK, Karch, A, Karimi, SE, Kayode, GA, Karyani, AK, Keiyoro, PN, Khader, YS, Khafaie, MA, Khammarnia, M, Khan, MS, Khan, EA, Khan, J, Khan, MN, Khatab, K, Khater, MM, Khatib, MN, Khayamzadeh, M, Khazaei, M, Khazaei, S, Khosravi, A, Khubchandani, J, Kianipour, N, Kim, YJ, Kimokoti, RW, Kinyoki, DK, Kisa, A, Kisa, S, Kolola, T, Komaki, H, Kosen, S, Koul, PA, Koyanagi, A, Kraemer, MUG, Krishan, K, Kuate Defo, B, Kumar, M, Kumar, P, Kumar, GA, Kusuma, D, La Vecchia, C, Lacey, B, Lad, SD, Lal, DK, Lam, F, Lami, FH, Lansingh, VC, Larson, HJ, Lasrado, S, Lee, SWH, Lee, PH, LeGrand, KE, Lenjebo, TL, Li, S, Liang, X, Liu, PY, Lopukhov, PD, Machado, DB, Mahasha, PW, Mahdavi, MM, Maheri, M, Mahotra, NB, Maled, V, Maleki, S, Malik, MA, Malta, DC, Mansour-Ghanaei, F, Mansouri, B, Mansourian, M, Mansournia, MA, Martins-Melo, FR, Masaka, A, Mayala, BK, Mehndiratta, MM, Mehri, F, Mehta, KM, Memiah, PTN, Mendoza, W, Menezes, RG, Mengesha, MB, Mengesha, EW, Mestrovic, T, Mihretie, KM, Miller-Petrie, MK, Mills, EJ, Milne, GJ, Mirabi, P, Mirrakhimov, EM, Mirzaei, R, Mirzaei, M, Mirzaei, HR, Mirzaei, H, Mirzaei-Alavijeh, M, Moazen, B, Moghadaszadeh, M, Mohamadi, E, Mohammad, DK, Mohammad, Y, Mohammad, KA, Mohammad Gholi Mezerji, N, Mohammadbeigi, A, Mohammadian-Hafshejani, A, Mohammadpourhodki, R, Mohammed, S, Mohammed, AS, Mohammed, H, Mohebi, F, Mokdad, AH, Monasta, L, Moosavi, MA, Moosazadeh, M, Moradi, G, Moradi, M, Moradi-Joo, M, Moradi-Lakeh, M, Moradzadeh, R, Moraga, P, Mosapour, A, Mouodi, S, Mousavi, SM, Khaneghah, AM, Mueller, UO, Muluneh, AG, Munro, SB, Murray, CJL, Murthy, GVS, Muthupandian, S, Naderi, M, Nagarajan, AJ, Naghavi, M, Nangia, V, Nansseu, JR, Nayak, VC, Nazari, J, Ndwandwe, DE, Negoi, I, Ngunjiri, JW, Nguyen, HLT, Nguyen, CTK, Nguyen, TH, Nigatu, YT, Nikbakhsh, R, Nikfar, S, Nikpoor, AR, Ningrum, DNA, Nnaji, CA, Oh, I-H, Oladnabi, M, Olagunju, AT, Olusanya, JO, Olusanya, BO, Bali, AO, Omer, MO, Onwujekwe, OE, Osgood-Zimmerman, AE, Owolabi, MO, P, A, M, Padubidri, JR, Pakshir, K, Pana, A, Pandey, A, Pando-Robles, V, Pashaei, T, Pasupula, DK, Paternina-Caicedo, AJ, Patton, GC, Pazoki Toroudi, H, Pepito, VCF, Pescarini, JM, Pigott, DM, Pilgrim, T, Pirsaheb, M, Poljak, M, Postma, MJ, Pourjafar, H, Pourmalek, F, Pourmirza, Kalhori, R, Prada, SI, Prakash, S, Quazi Syed, Z, Quintana, H, Rabiee, N, Rabiee, M, Radfar, A, Rafiei, A, Rahim, F, Rajati, F, Rameto, MA, Ramezanzadeh, K, Ranabhat, CL, Rao, SJ, Rasella, D, Rastogi, P, Rathi, P, Rawaf, S, Rawaf, DL, Rawal, L, Rawassizadeh, R, Rawat, R, Renjith, V, Renzaho, AMN, Reshmi, B, Reta, MA, Rezaei, N, Rezai, MS, Rezapour, A, Riahi, SM, Ribeiro, AI, Rickard, J, Rios-Blancas, M, Rios-González, CM, Roever, L, Rostamian, M, Rubino, S, Rwegerera, GM, Saad, AM, Saadatagah, S, Sabour, S, Sadeghi, E, Moghaddam, SS, Saeidi, S, Sagar, R, Sahebkar, A, Sahraian, MA, Sajadi, SM, Salahshoor, MR, Salam, N, Salem, H, Salem, MR, Salomon, JA, Kafil, HS, Sambala, EZ, Samy, AM, Saraswathy, SYI, Sarmiento-Suárez, R, Saroshe, S, Sartorius, B, Sarveazad, A, Sathian, B, Sathish, T, Schaeffer, LE, Schwebel, DC, Senthilkumaran, S, Shabaninejad, H, Shahabi, S, Shaheen, AA, Shaikh, MA, Shalash, AS, Shams-Beyranvand, M, Shamsi, MB, Shamsizadeh, M, Sharafi, K, Sharifi, H, Sheikh, A, Sheikhtaheri, A, Shetty, RS, Shiferaw, WS, Shigematsu, M, Shin, JI, Shirkoohi, R, Siabani, S, Siddiqi, TJ, Silverberg, JIS, Simonetti, B, Singh, JA, Sinha, DN, Sinke, AH, Soheili, A, Sokhan, A, Soltani, S, Soofi, M, Sorrie, MB, Soyiri, IN, Spotin, A, Spurlock, EE, Sreeramareddy, CT, Sudaryanto, A, Sufiyan, MB, Suleria, HAR, Abdulkader, RS, Taherkhani, A, Tapak, L, Taveira, N, Taymoori, P, Tefera, YM, Tehrani-Banihashemi, A, Teklehaimanot, BF, Tekulu, GH, Tesfay, BE, Tessema, ZT, Tessema, B, Thankappan, KR, Tohidinik, HR, Topor-Madry, R, Tovani-Palone, MR, Tran, BX, Uddin, R, Ullah, I, Umeokonkwo, CD, Unnikrishnan, B, Upadhyay, E, Usman, MS, Vaezi, M, Valadan, Tahbaz, S, Valdez, PR, Vasseghian, Y, Veisani, Y, Violante, FS, Vollmer, S, Waheed, Y, Wakefield, J, Wang, Y, Wang, Y-P, Weldesamuel, GT, Werdecker, A, Westerman, R, Wiangkham, T, Wiens, KE, Wiysonge, CS, Woldu, G, Wondafrash, DZ, Wonde, TE, Wu, A-M, Yadollahpour, A, Jabbari, SHY, Yamada, T, Yaya, S, Yazdi-Feyzabadi, V, Yeheyis, TY, Yeshaw, Y, Yilgwan, CS, Yip, P, Yonemoto, N, Younis, MZ, Yousefi, Z, Yousefifard, M, Yousefinezhadi, T, Yu, C, Yusefzadeh, H, Zadey, S, Zahirian, Moghadam, T, Zaki, L, Zaman, SB, Zamani, M, Zamanian, M, Zandian, H, Zangeneh, A, Zarei, F, Zerfu, TA, Zhang, Y, Zhang, Z-J, Zhao, X-JG, Zhou, M, Ziapour, A, Hay, SI, Lim, SS, Mosser, JF, Local Burden of Disease Vaccine Coverage Collaborators, Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Value, Affordability and Sustainability (VALUE), Microbes in Health and Disease (MHD), HUS Comprehensive Cancer Center, Clinicum, Department of Oncology, Sbarra, Alyssa N., Rolfe, Sam, Nguyen, Jason Q., Earl, Lucas, Ahmed, MB, Mosser, Jonathan F, Collaborators, Local Burden of Disease Vaccine Coverage, Bill & Melinda Gates Foundation, Alexander von Humboldt-Stiftung, Unión Europea. Fondo Europeo de Desarrollo Regional (FEDER/ERDF), Universiti Sains Malaysia (Malasia), Panjab University (India), NIHR - Oxford Biomedical Research Centre (Reino Unido), Australian Research Council, Instituto de Saúde Pública da Universidade do Porto, Local Burden Dis Educ Attainment C, Local Burden of Disease Vaccine Coverage Collaborator, and Violante FS
Subjects: and promotion of well-being, Vacunación Masiva, Internationality, Disease prevention, children under 5 years old, Geographic Mapping, Rural Health, medicine.disease_cause, Cross-reactivity, 0302 clinical medicine, RA0421, Vaccination Refusal, 030212 general & internal medicine, Child, immunity patterns, Pediatric, 0303 health sciences, Public health, Multidisciplinary, biology, Vaccination, Uncertainty, IMMUNIZATION, 3142 Public health care science, environmental and occupational health, COVERAGE, 3. Good health, TIME, 3.4 Vaccines, Child, Preschool, Infectious diseases, A990 Medicine and Dentistry not elsewhere classified, Antibody, Engineering sciences. Technology, AFRICA, General Science & Technology, Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), COVID-19, 610 Medicine & health, Global Vaccine Action Plan (GVAP), Local Burden of Disease Vaccine Coverage Collaborators, Article, Vaccine Related, 03 medical and health sciences, measles vaccine, Measels, Low- and middle-income countries, Local burden of disease, Clinical Research, medicine, Humans, Healthcare Disparities, Preschool, PROGRESS, 030304 developmental biology, business.industry, MORTALITY, Developed Countries, Prevention, Comment, Vacunación, Urban Health, Prevention of disease and conditions, Virology, Coronavirus, Good Health and Well Being, Cobertura de Vacunación, biology.protein, Immunization, business, Measles
Abstract: The safe, highly effective measles vaccine has been recommended globally since 1974, yet in 2017 there were more than 17 million cases of measles and 83,400 deaths in children under 5 years old, and more than 99% of both occurred in low- and middle-income countries (LMICs)1–4. Globally comparable, annual, local estimates of routine first-dose measles-containing vaccine (MCV1) coverage are critical for understanding geographically precise immunity patterns, progress towards the targets of the Global Vaccine Action Plan (GVAP), and high-risk areas amid disruptions to vaccination programmes caused by coronavirus disease 2019 (COVID-19)5–8. Here we generated annual estimates of routine childhood MCV1 coverage at 5 × 5-km2 pixel and second administrative levels from 2000 to 2019 in 101 LMICs, quantified geographical inequality and assessed vaccination status by geographical remoteness. After widespread MCV1 gains from 2000 to 2010, coverage regressed in more than half of the districts between 2010 and 2019, leaving many LMICs far from the GVAP goal of 80% coverage in all districts by 2019. MCV1 coverage was lower in rural than in urban locations, although a larger proportion of unvaccinated children overall lived in urban locations; strategies to provide essential vaccination services should address both geographical contexts. These results provide a tool for decision-makers to strengthen routine MCV1 immunization programmes and provide equitable disease protection for all children., Although progress in the coverage of routine measles vaccination in children in low- and middle-income countries was made during 2000–2019, many countries remain far from the goal of 80% coverage in all districts by 2019.
Published: 2021

9. Five insights from the Global Burden of Disease Study 2019.

Author: Hamadeh R.R., Soyiri I.N., Sreeramareddy C.T., Srinivasan V., Sripada K., Stovner L.J., Stockfelt L., Sultan I., Swope C.B., Vaicekonyte R., Sykes B.L., Szumowski L., Tabb K.M., Tabuchi T., Taddele B.W., Tahir Z., Tareque M.I., Tarigan I.U., Taveira N., Thankappan K.R., Thomas N., Varughese S., Touvier M., Tran B.X., Tsatsakis A., Vardavas C., Ullah I., Umeokonkwo C.D., Undurraga E.A., Upadhyay E., Vasankari T.J., Vasconcelos A.N., Veisani Y., Vidale S., Waheed Y., Wei J., Wang F., Zhao X.G., Wang Y., Yu C., Zhang Z., Wang H., Weiss J., Wiangkham T., Wickramasinghe N.D., Wu A., Xie Y., Xu G., Yahyazadeh Jabbari S., Yilgwan C.S., Yonemoto N., Younis M.Z., Younker T.P., Yu Y., Zaidi S., Zhang J., Zhang Y., Zheleva B., Zhu C., Abbafati C., Machado D.B., Cislaghi B., Salman O.M., Karanikolos M., McKee M., Abbas K.M., Brady O.J., Larson H.J., Trias-Llimos S., Cummins S., Langan S.M., Sartorius B., Hafiz A., Jenabi E., Mohammad Gholi Mezerji N., Borzouei S., Azarian G., Khazaei S., Abbasi M., Asghari B., Masoumi S., Komaki H., Taherkhani A., Adabi M., Abbasifard M., Bazmandegan G., Kamiab Z., Vakilian A., Anjomshoa M., Mokari A., Sabour S., Shahbaz M., Saeedi R., Ahmadieh H., Yousefinezhadi T., Haj-Mirzaian A., Nikbakhsh R., Safi S., Asgari S., Irvani S.N., Jahanmehr N., Ramezanzadeh K., Abbasi-Kangevari M., Khayamzadeh M., Abbastabar H., Shirkoohi R., Fazlzadeh M., Janjani H., Hosseini M., Mansournia M., Tohidinik H., Bakhtiari A., Fazaeli A., Mousavi S., Hasanzadeh A., Nabavizadeh B., Malekzadeh R., Hashemian M., Pourshams A., Salimzadeh H., Sepanlou S.G., Afarideh M., Esteghamati A., Esteghamati S., Ghajar A., Heidari B., Rezaei N., Mohamadi E., Rahimi-Movaghar A., Rahim F., Eskandarieh S., Sahraian M., Mohebi F., Aminorroaya A., Ebrahimi H., Farzadfar F., Mohajer B., Pishgar F., Saeedi Moghaddam S., Shabani M., Zarafshan H., Abolhassani H., Hafezi-Nejad N., Heidari-Soureshjani R., Abdollahi M., Farahmand M., Salamati P., Mehrabi Nasab E., Tajdini M., Aghamir S., Mirzaei R., Dibaji Forooshani Z., Khater M.M., Abd-Allah F., Abdelalim A., Abualhasan A., El-Jaafary S.I., Hassan A., Elsharkawy A., Khater A.M., Elhabashy H.R., Salem M.R.R., Salem H., Sadeghi M., Jafarinia M., Amini-Rarani M., Mohammadifard N., Sarrafzadegan N., Abdollahpour I., Sarveazad A., Tehrani-Banihashemi A., Yoosefi Lebni J., Manafi N., Pazoki Toroudi H., Dorostkar F., Alipour V., Sheikhtaheri A., Arabloo J., Azari S., Ghashghaee A., Rezapour A., Naserbakht M., Kabir A., Mehri F., Yousefifard M., Asadi-Aliabadi M., Babaee E., Eshrati B., Goharinezhad S., Moradi M., Abedi P., Rashedi V., Kumar V., Elgendy I.Y., Basu S., Park J., Pereira A., Norheim O.F., Eagan A.W., Cahill L.E., Sheikh A., Abushouk A.I., Thakur B., Barnighausen T.W., Shrime M.G., Abedi A., Doshi C.P., Abegaz K.H., Geberemariyam B.S., Aynalem Y.A., Shiferaw W.S., Abosetugn A.E., Aboyans V., Abrams E.M., Gitimoghaddam M., Kissoon N., Stubbs J.L., Brauer M., Iyamu I.O., Kopec J.A., Pourmalek F., Ribeiro A.P., Malta D.C., Gomez R.S., Abreu L.G., Abrigo M.R.M., Almulhim A.M., Dahlawi S.M.A., Pottoo F.H., Menezes R.G., Alanzi T.M., Alumran A.K., Abu Haimed A.K., Madadin M., Alanezi F.M., Abu-Gharbieh E., Saddik B., Abu-Raddad L.J., Samy A.M., El Nahas N., Shalash A.S., Nabhan A.F., Kamath A.M., Kassebaum N.J., Aravkin A.Y., Kochhar S., Sorensen R.J.D., Afshin A., Burkart K., Cromwell E.A., Gakidou E., Hay S.I., Kyu H.H., Lopez A.D., Lozano R., Misganaw A.T., Mokdad A.H., Naghavi M., Pigott D.M., Reiner Jr R.C., Roth G.A., Stanaway J.D., Vollset S., Vos T., Lim S.S., Murray C.J.L., Kalani R., Ikuta K.S., Cho D.Y., Kneib C.J., Crowe C.S., Massenburg B.B., Morrison S.D., Acebedo A., Adelson J.D., Agesa K.M., Alam T., Albertson S.B., Anderson J.A., Antony C.M., Ashbaugh C., Assmus M., Azhar G., Balassyano S., Bannick M.S., Barthelemy C.M., Bender R.G., Bennitt F.B., Bertolacci G.J., Biehl M.H., Bisignano C., Boon-Dooley A.S., Briant P.S., Bryazka D., Bumgarner B.R., Callender C.S., Cao J., Castle C.D., Castro E., Causey K., Cercy K.M., Chalek J., Cohen A.J., Comfort H., Compton K., Croneberger A.J., Cruz J.A., Cunningham M., Dangel W.J., Dean F.E., DeCleene N.K., Deen A., Degenhardt L., Dingels Z.V., Dippenaar I.N., Dirac M.A., Dolgert A.J., Emmons-Bell S., Estep K., Farag T., Feigin V.L., Feldman R., Ferrara G., Ferrari A.J., Fitzgerald R., Force L.M., Fox J.T., Frank T.D., Fu W., Fukutaki K., Fuller J.E., Fullman N., Galles N.C., Gardner W.M., Gershberg Hayoon A., Goren E., Gorman T.M., Gottlich H.C., Guo G., Haddock B., Hagins H., Haile L.M., Hamilton E.B., Han C., Han H., Harvey J.D., Henny K., Henrikson H.J., Henry N.J., Herbert M.E., Hsiao T., Huynh C.K., Iannucci V.C., Ippolito H., Irvine C.M.S., Jafari H., Jahagirdar D., James S.L., Johnson C.O., Johnson S.C., Keller C., Kemmer L., Kendrick P.J., Knight M., Kocarnik J.M., Krohn K.J., Larson S.L., Lau K.M., Ledesma J.R., Leever A.T., LeGrand K.E., Lescinsky H., Lin C., Liu H., Liu Z., Lo J., Lu A., Ma J., Maddison E.R., Manguerra H., Marks A., Martopullo I., Mastrogiacomo C.I., May E.A., Mooney M.D., Mosser J.F., Mullany E.C., Mumford J., Munro S.B., Nandakumar V., Nguyen J., Nguyen M., Nichols E., Nixon M.R., Odell C.M., Ong K.L., Orji A.U., Ostroff S.M., Pasovic M., Paulson K.R., Pease S.A., Pennini A., Pierce M., Pilz T.M., Pletcher M., Rao P.C., Razo C., Redford S.B., Reinig N., Reitsma M.B., Rhinehart P., Robalik T., Roberts N.L.S., Rolfe S., Sbarra A.N., Schaeffer L.E., Shackelford K.A., Shadid J., Sharara F., Shaw D.H., Sheena B.S., Simpson K.E., Smith A., Spencer C.N., Spurlock E.E., Stark B.A., Steiner C., Steuben K.M., Sylte D.O., Tang M., Taylor H.J., Terrason S., Thomson A.M., Torre A.E., Travillian R., Troeger C.E., Vongpradith A., Walters M.K., Wang J., Watson A., Watson S., Whisnant J.L., Whiteford H.A., Wiens K.E., Wilner L.B., Wilson S., Wool E.E., Wozniak S.S., Wu J., Wulf Hanson S., Wunrow H., Xu R., Yadgir S., Yearwood J.A., York H.W., Yuan C., Zhao J.T., Zheng P., Zimsen S.R.M., Zlavog B.S., Chang A.Y., Oren E., Buchbinder R., Chin K.L., Guo Y., Polkinghorne K.R., Thrift A.G., Ackerman I.N., Cicuttini F.M., Li S., Zaman S., Suleria H., Cowie B.C., Wijeratne T., Patton G.C., Sawyer S.M., Adair T., Meretoja A., Adetokunboh O.O., Adamu A.A., Iwu C.J., Parry C.D.H., Seedat S., Ndwandwe D.E., Mahasha P.W., Stein D.J., Nnaji C.A., Sambala E.Z., Wiysonge C.S., Adebayo O.M., Ilesanmi O.S., Owolabi M.O., Adeoye A.M., Adedeji I.A., Adekanmbi V., Ibitoye S.E., John-Akinola Y.O., Oluwasanu M.M., Oghenetega O.B., Akinyemi R.O., Zandian H., Adham D., Zahirian Moghadam T., Advani S.M., Teagle W.L., Braithwaite D., Agasthi P., Saadatagah S., Afshari M., Agardh E.E., Allebeck P., Danielsson A., Deuba K., Carrero J.J., Fereshtehnejad S., Arnlov J., Nowak C., Cederroth C.R., Ahmadi A., Mills E.J., Kurmi O.P., Olagunju A.T., Agarwal G., Sathish T., Aghaali M., Mohammadbeigi A., Agrawal A., Ahmad T., Ahmadi K., Maleki S., Naderi M., Salahshoor M.R., Pourmirza Kalhori R., Almasi 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Abstract: The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a rules-based synthesis of the available evidence on levels and trends in health outcomes, a diverse set of risk factors, and health system responses. GBD 2019 covered 204 countries and territories, as well as first administrative level disaggregations for 22 countries, from 1990 to 2019. Because GBD is highly standardised and comprehensive, spanning both fatal and non-fatal outcomes, and uses a mutually exclusive and collectively exhaustive list of hierarchical disease and injury causes, the study provides a powerful basis for detailed and broad insights on global health trends and emerging challenges. GBD 2019 incorporates data from 281 586 sources and provides more than 3.5 billion estimates of health outcome and health system measures of interest for global, national, and subnational policy dialogue. All GBD estimates are publicly available and adhere to the Guidelines on Accurate and Transparent Health Estimate Reporting. From this vast amount of information, five key insights that are important for health, social, and economic development strategies have been distilled. These insights are subject to the many limitations outlined in each of the component GBD capstone papers.Copyright © 2020 Elsevier Ltd
Published: 2020

10. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950-2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019.

Author: Hird T.R., Shannawaz M., Sharma R., Shin J., Shiri R., Sierpinski R., Sigurvinsdottir R., Silva D.A.S., Simonetti B., Singh A., Sinha D.N., Skiadaresi E., Skou S.T., Skryabin V.Y., Zastrozhin M.S., Soheili A., Sokhan A., Somefun O.D., Korotkova A.V., Soyiri I.N., Sreeramareddy C.T., Srinivasan V., Sripada K., Stovner L.J., Stockfelt L., Sultan I., Swope C.B., Vaicekonyte R., Sykes B.L., Szumowski L., Tabb K.M., Tabuchi T., Taddele B.W., Tahir Z., Tareque M.I., Tarigan I.U., Taveira N., Thankappan K.R., Thomas N., Varughese S., Touvier M., Tran B.X., Tsatsakis A., Vardavas C., Ullah I., Umeokonkwo C.D., Undurraga E.A., Upadhyay E., Vasankari T.J., Vasconcelos A.N., Veisani Y., Vidale S., Waheed Y., Wei J., Wang F., Zhao X.G., Wang Y., Yu C., Zhang Z., Wang H., Weiss J., Wiangkham T., Wickramasinghe N.D., Wu A., Xie Y., Xu G., Yahyazadeh Jabbari S., Yilgwan C.S., Yonemoto N., Younis M.Z., Younker T.P., Yu Y., Zaidi S., Zhang J., Zhang Y., Zheleva B., Zhu C., Abbafati C., Machado D.B., Cislaghi B., Salman O.M., Karanikolos M., McKee M., Abbas K.M., Brady O.J., Larson H.J., Trias-Llimos S., Cummins S., Langan S.M., Sartorius B., Hafiz A., Jenabi E., Mohammad Gholi Mezerji N., Borzouei S., Azarian G., Khazaei S., Abbasi M., Asghari B., Masoumi S., Komaki H., Taherkhani A., Adabi M., Abbasifard M., Bazmandegan G., Kamiab Z., Vakilian A., Anjomshoa M., Mokari A., Sabour S., Shahbaz M., Saeedi R., Ahmadieh H., Yousefinezhadi T., Haj-Mirzaian A., Nikbakhsh R., Safi S., Asgari S., Irvani S.N., Jahanmehr N., Ramezanzadeh K., Abbasi-Kangevari M., Khayamzadeh M., Abbastabar H., Shirkoohi R., Fazlzadeh M., Janjani H., Hosseini M., Mansournia M., Tohidinik H., Bakhtiari A., Fazaeli A., Mousavi S., Hasanzadeh A., Nabavizadeh B., Malekzadeh R., Hashemian M., Pourshams A., Salimzadeh H., Sepanlou S.G., Afarideh M., Esteghamati A., Esteghamati S., Ghajar A., Heidari B., Rezaei N., Mohamadi E., Rahimi-Movaghar A., Rahim F., Eskandarieh S., Sahraian M., Mohebi F., Aminorroaya 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N., Mithra P., Shetty R.S., Thapar R., Padubidri J., Bakkannavar S.M., Nayak V.C., Rastogi P., Shetty B.K., Bhageerathy R., Gudi N., Boloor A., Holla R., Rathi P., Unnikrishnan B., Janodia M.D., Lang J.J., Badawi A., Orpana H.M., Bhutta Z.A., Shield K.D., Chattu V., Badiye A.D., Kapoor N., Bagherzadeh M., Rabiee N., Bagli E., Baig A.A., Bairwa M., Lodha R., Sagar R., Rath G.K., Bhardwaj P., Charan J., Kanchan T., Joshi A., Pakhare A.P., Bakhshaei M., Naghshtabrizi B., Balachandran A., Hoek H.W., Postma M.J., Geremew A., Gebrehiwot A.M., Balakrishnan S., Desalew A., Bojia H.A., Mohammed A.S., Regassa L.D., Parmar P.G.K., Balalla S., Roberts S., Baldasseroni A., Stokes M.A., Ball K., Islam S., Maddison R., Balzi D., Levi M., Banach M., Banerjee S.K., Banik P.C., Barua L., Faruque M., Barboza M.A., Barker-Collo S.L., Jonas J.B., Panda-Jonas S., De Neve J., Kohler S., Moazen B., Mohammed S., Barrero L.H., Basaleem H., Bassat Q., Haro J.M., Koyanagi A., Car J., Greaves F., Majeed A., Davis A.C., Steiner T.J., Kusuma D., Palladino R., Saxena S., Baune B.T., Karch A., Baye B.A., Darega Gela J., Kolola T., Becker J.S., DeLang M., West J., Gad M.M., Serre M.L., Gallus S., Lugo A., Beghi E., Pupillo E., Bosetti C., Giussani G., Bikbov B., Perico N., Remuzzi G., Imani-Nasab M., Nouraei Motlagh S., Sharafi Z., Behzadifar M., Bejot Y., Bekuma T.T., Yilma M.T., Bell M.L., Bello A.K., Rafiee A., Keddie S.H., Lucas T.C.D., Dolecek C., Dunachie S.J., Kraemer M.U.G., Rumisha S.F., Weiss D.J., Lewington S., Collins E.L., Nandi A.K., Zhao Y., Bennett D.A., Karim M.A., Lacey B., Khundkar R., Yaya S., Goulart A.C., Santos I.S., Bensenor I.M., Lotufo P.A., Tovani-Palone M.R., Castaldelli-Maia J., Furtado J.M., Benziger C.P., Berman A.E., Mazidi M., Bernabe E., Dargan P.I., Molokhia M., Shibuya K., Douiri A., Wolfe C.D.A., Hay R.J., Flohr C., Suchdev P.S., Ram P., Bernstein R.S., Liu Y., Bhagavathula A.S., Khan G., Grivna M., Bhala N., Chandan J.S., Gaidhane A.M., Quazi Syed Z., Saxena D., 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Castelpietra G., Catala-Lopez F., Pakhale S., Cerin E., Yip P., Ho H., Chang J., Chang A.R., Chang K., Cooper O.R., Chaturvedi S., Chimed-Ochir O., Chirinos-Caceres J.L., Choi J.J., Christensen H., Truelsen T.C., Chu D., Kivimaki M., Chung S., Ward J.L., Chung M.T., Cirillo M., Virclo R., Classen T.K.D., Lauriola P., Corso B., Hugo F.N., Kieling C., Cousin E., Duncan B.B., Goulart B.N.G., Schmidt M.I., Stein C., Cowden R.G., MacLachlan J.H., Leigh J., Cross M., Ferreira M.L., Smith E.U.R., Driscoll T.R., Huda T.M., Hoy D.G., Horita N., Cross D.H., Dai H., Hu G., Damasceno A.A.M., Damiani G., La Vecchia C., Sanabria J., Pandey A., Mathur M.R., Zodpey S., Dandona L., Dandona R., Kumar G., Lal D.K., Hamagharib Abdullah K., Hosseinzadeh M., Darwesh A.M., Faraj A., Omar Bali A., Das Gupta R., Dash A.P., Davey G., Deribe K., Gebremedhin K.B., Wondmieneh A.B., Dereje N.D., Davila-Cervantes C.A., Davletov K., Mereke A., Serdar B., Gebremeskel G.G., Haile T.G., Tadesse D.B., Weldesamuel G.T., Demoz G.T., Gebremeskel L.G., Woldu G., Handiso D., Dervenis N., Topouzis F., Desai R., Dharmaratne S.D., Dhungana G.P., Emamian M., Diaz D., Djalalinia S., Nguyen T.H., Vu G.T., Do H.T., Dokova K., Doku D.T., Neupane S., Takala J.S., Doxey M.C., Doyle K.E., Renzaho A.M.N., Ogbo F.A., Robinson S.R., Vukovic A., Ilic I.M., Santric-Milicevic M.M., Vujcic I.S., Dubljanin E., Vukovic R., Rasella D., Duraes A.R., Ebrahimi Kalan M., Effiong A., Pond C.D., Ehrlich J.R., Liu X., Wei M.Y.W., El Sayed I., El Tantawi M., El Sayed Zaki M., Elbarazi I., Tsai A.C., Elyazar I.R., Yazdi-Feyzabadi V., Eskandari K., Sharifi H., Halvaei I., Ghaffarifar F., Zaki L., Hasanpoor E., Esmaeilzadeh F., Etemadi A., Lan Q., Yeheyis T.Y., Etisso A.E., Ezekannagha O., e Farinha C.S., Farioli A., Violante F.S., Faris P.S., Mohammad D.K., Faro A., Lam J.O., Filip I., Fischer F., Flor L.S., Foigt N.A., Folayan M.O., Fomenkov A.A., Foroutan M., Francis J.M., Franklin R.C., Fukumoto T., Gamkrelidze A., Kereselidze M., 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Moradi-Joo M., Morawska L., Mousavi Khaneghah A., Westerman R., Werdecker A., Mueller U.O., Mukhopadhyay S., Musa K., Mustafa G., Nagarajan A.J., Nagel G., Rothenbacher D., Naik G., Schwebel D.C., Singh J.A., Naimzada M., Otstavnov N., Otstavnov S.S., Soshnikov S., Titova M.V., Nair S., Naldi L., Nangia V., Nansseu J., Sobngwi E., Nguefack-Tsague G., Ndejjo R., Ngari K.N., Ngunjiri J.W., Nigatu Y.T., Oancea B., Oh I., Okunga E.W., Olusanya J.O., Olusanya B.O., Ong S., Onwujekwe O.E., Ortega-Altamirano D.V., Ortiz A., Soriano J.B., Osarenotor O., Ostojic S.M., Vlassov V., Pa M., Pangaribuan H.U., Park E., Pasupula D., Patel J.R., Patel S.K., Paternina-Caicedo A.J., Pathak M., Pathak A., Patten S.B., Tonelli M., Weintraub R.G., Paudel S., Pepito V.F., Thurston G.D., Peprah E.K., Pereira J., Pescarini J.M., Piccinelli C., Pilgrim T., Plass D., Pokhrel K.N., Prada S.I., Prakash V., Prakash S., Prasad N., Shigematsu M., Pribadi D.R.A., Sudaryanto A., Rabiee M., Radfar A., Ranabhat C.L., Ranta A., Ribeiro D.C., Rao S., Rawaf D.L., Rawal L., Renjith V., Rickard J., Roever L., Romoli M., Rostamian M., Rubagotti E., Rwegerera G.M., Ullah S., Sajadi S., Salam N., Salomon J.A., Salz I., Saraswathy S.Y., Sarmiento-Suarez R., Sathian B., Savic M., Saylan M., Schwendicke F., Sekerija M., Senthilkumaran S., Sha F., Shaheen A.A., Shaikh M.A., and Shamsizadeh M.
Abstract: Background: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Method(s): 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10-14 and 50-54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated using a B
Published: 2020

11. Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000-17.

Author: Sathish T., Tesfay B.E., Tesfay F.H., Tessema B., Tessema Z.T., Thankappan K.R., Thomas N., Toma A., Topor-Madry R., Tovani-Palone M.R., Traini E., Tran B.X., Tran K.B., Ullah I., Unnikrishnan B., Usman M.S., Uzochukwu B.S.C., Valdez P.R., Varughese S., Violante F.S., Vollmer S., Whawariat F.G., Waheed Y., Wallin M.T., Wang Y., Wang Y.-P., Weaver M., Weji B.G., Weldesamuel G.T., Welgan C.A., Werdecker A., Westerman R., Wiangkham T., Wiysonge C.S., Wolde H.F., Wondafrash D.Z., Wonde T.E., Worku G.T., Wu A.-M., Xu G., Yadollahpour A., Yahyazadeh Jabbari S.H., Yamada T., Yatsuya H., Yeshaneh A., Yilgwan C.S., Yilma M.T., Yip P., Yisma E., Yonemoto N., Yoon S.-J., Younis M.Z., Yousefifard M., Yousof H.-A.S.A., Yu C., Yusefzadeh H., Zadey S., Zaidi Z., Zaman S.B., Zamani M., Zandian H., Zepro N.B., Zerfu T.A., Zhang Y., Zhao X.-J.G., Ziapour A., Zodpey S., Zuniga Y.M.H., Hay S.I., Reiner R.C., Singh A., Wiens K.E., Lindstedt P.A., Blacker B.F., Johnson K.B., Baumann M.M., Schaeffer L.E., Abbastabar H., Abd-Allah F., Abdelalim A., Abdollahpour I., Abegaz K.H., Abejie A.N., Abreu L.G., Abrigo M.R.M., Abualhasan A., Accrombessi M.M.K., Acharya D., Adabi M., Adamu A.A., Adebayo O.M., Adedoyin R.A., Adekanmbi V., Adetokunboh O.O., Adhena B.M., Afarideh M., Ahmad S., Ahmadi K., Ahmed A.E., Ahmed M.B., Ahmed R., Akalu T.Y., Alahdab F., Al-Aly Z., Alam N., Alam S., Alamene G.M., Alanzi T.M., Alcalde-Rabanal J.E., Ali B.A., Alijanzadeh M., Alipour V., Aljunid S.M., Almasi A., Almasi-Hashiani A., Al-Mekhlafi H.M., Altirkawi K.A., Alvis-Guzman N., Alvis-Zakzuk N.J., Amini S., Amit A.M.L., Andrei C.L., Anjomshoa M., Anoushiravani A., Ansari F., Antonio C.A.T., Antony B., Antriyandarti E., Arabloo J., Aref H.M.A., Aremu O., Armoon B., Arora A., Aryal K.K., Arzani A., Asadi-Aliabadi M., Atalay H.T., Athari S.S., Athari S.M., Atre S.R., Ausloos M., Awoke N., Ayala Quintanilla B.P., Ayano G., Ayanore M.A., Aynalem Y.A., Azari S., Azzopardi P.S., Babaee E., Babalola T.K., Badawi A., Bairwa M., Bakkannavar S.M., Balakrishnan S., Bali A.G., Banach M., Banoub J.A.M., Barac A., Barnighausen T.W., Basaleem H., Basu S., Bay V.D., Bayati M., Baye E., Bedi N., Beheshti M., Behzadifar M., Bekele B.B., Belayneh Y.M., Bell M.L., Bennett D.A., Berbada D.A., Bernstein R.S., Bhat A.G., Bhattacharyya K., Bhattarai S., Bhaumik S., Bhutta Z.A., Bijani A., Bikbov B., Birihane B.M., Biswas R.K., Bohlouli S., Bojia H.A., Boufous S., Brady O.J., Bragazzi N.L., Briko A.N., Briko N.I., Britton G.B., Burugina Nagaraja S., Busse R., Butt Z.A., Camera L.A., Campos-Nonato I.R., Cano J., Car J., Cardenas R., Carvalho F., Castaneda-Orjuela C.A., Castro F., Chanie W.F., Chatterjee P., Chattu V.K., Chichiabellu T.Y., Chin K.L., Christopher D.J., Chu D.-T., Cormier N.M., Costa V.M., Culquichicon C., Daba M.S., Damiani G., Dandona L., Dandona R., Dang A.K., Darwesh A.M., Darwish A.H., Daryani A., Das J.K., Das Gupta R.D., Dash A.P., Davey G., Davila-Cervantes C.A., Davis A.C., Davitoiu D.V., De la Hoz F.P., Demis A.B., Demissie D.B., Demissie G.D., Demoz G.T., Denova-Gutierrez E., Deribe K., Desalew A., Deshpande A., Dharmaratne S.D., Dhillon P., Dhimal M., Dhungana G.P., Diaz D., Dipeolu I.O., Djalalinia S., Doyle K.E., Dubljanin E., Duko B., Duraes A.R., Ebrahimi Kalan M., Edinur H.A., Effiong A., Eftekhari A., El Nahas N., El Sayed I., El Sayed Zaki M., El Tantawi M., Elema T.B., Elhabashy H.R., El-Jaafary S.I., Elkout H., Elsharkawy A., Elyazar I.R.F., Endalamaw A., Endalew D.A., Eskandarieh S., Esteghamati A., Esteghamati S., Etemadi A., Ezekannagha O., Fareed M., Faridnia R., Farzadfar F., Fazlzadeh M., Feigin V.L., Fereshtehnejad S.-M., Fernandes E., Filip I., Fischer F., Foigt N.A., Folayan M.O., Foroutan M., Franklin R.C., Fukumoto T., Gad M.M., Gayesa R.T., Gebre T., Gebremedhin K.B., Gebremeskel G.G., Gesesew H.A., Gezae K.E., Ghadiri K., Ghashghaee A., Ghimire P.R., Gill P.S., Gill T.K., Ginindza T.G., Gomes N.G., Gopalani S.V., Goulart A.C., Goulart B.N.G., Grada A., Gubari M.I.M., Gugnani H.C., Guido D., Guimaraes R.A., Guo Y., Gupta R., Hafezi-Nejad N., Haile D.H., Hailu G.B., Haj-Mirzaian A., Hamadeh R.R., Hamidi S., Handiso D.W., Haririan H., Hariyani N., Hasaballah A.I., Hasan M.M., Hasanpoor E., Hasanzadeh A., Hassankhani H., Hassen H.Y., Hegazy M.I., Heibati B., Heidari B., Hendrie D., Henry N.J., Herteliu C., Heydarpour F., Hidru H.D.D., Hird T.R., Hoang C.L., Homaie Rad E.H., Hoogar P., Hoseini M., Hossain N., Hosseini M., Hosseinzadeh M., Househ M., Hsairi M., Hu G., Hussen M.M., Ibitoye S.E., Igumbor E.U., Ilesanmi O.S., Ilic M.D., Imani-Nasab M.H., Iqbal U., Irvani S.S.N., Islam S.M.S., Iwu C.J., Izadi N., Jaca A., Jahanmehr N., Jakovljevic M., Jalali A., Jayatilleke A.U., Jha R.P., Jha V., Ji J.S., Jonas J.B., Jozwiak J.J., Kabir A., Kabir Z., Kahsay A., Kalani H., Kanchan T., Karami Matin B., Karch A., Karim M.A., Karimi-Sari Surendra Karki H., Kasaeian A., Kasahun G.G., Kasahun Y.C., Kasaye H.K., Kassa G.G., Kassa G.M., Kayode G.A., Kazemi Karyani A., Kebede M.M., Keiyoro P.N., Kelbore A.G., Kengne A.P., Ketema D.B., Khader Y.S., Khafaie M.A., Khalid N., Khalilov R., Khan E.A., Khan J., Khan M.N., Khan M.S., Khatab K., Khater A.M., Khater M.M., Khayamzadeh M., Khazaei M., Khazaei S., Khosravi M.H., Khubchandani J., Kiadaliri A., Kim Y.J., Kimokoti R.W., Kisa A., Kisa S., Kissoon N., Shivakumar K.M., Kochhar S., Kolola T., Komaki H., Kosen S., Koul P.A., Koyanagi A., Kraemer M.U.G., Krishan K., Kugbey N., Kumar G.A., Kumar M., Kumar P., Kumar V., Kusuma D., La Vecchia C., Lacey B., Lad S.D., Lal D.K., Lam F., Lami F.H., Lamichhane P., Lansingh V.C., Lasrado S., Laxmaiah A., Lee P.H., LeGrand K.E., Leili M., Lenjebo T.L., Leshargie C.T., Levine A.J., Li S., Linn S., Liu S., Lodha R., Longbottom J., Lopez J.C.F., Magdy Abd El Razek H., Magdy Abd El Razek M., Mahadeshwara Prasad DR., Mahasha P.W., Mahotra N.B., Majeed A., Malekzadeh R., Malta D.C., Mamun A.A., Manafi N., Manda A.L., Manohar N.D.D., Mansournia M.A., Mapoma C.C., Maravilla J.C., Martinez G., Martini S., Martins-Melo F.R., Masaka A., Massenburg B.B., Mathur M.R., Mayala B.K., Mazidi M., McAlinden C., Meharie B.G., Mehndiratta M.M., Mehta K.M., Mekonnen T.C., Meles G.G., Memiah P.T.N., Memish Z.A., Mendoza W., Menezes R.G., Mereta S.T., Meretoja T.J., Mestrovic T., Miazgowski B., Mihretie K.M., Miller T.R., Mini G.K., Mirrakhimov E.M., Moazen B., Mohajer B., Mohamadi-Bolbanabad A., Mohammad D.K., Mohammad K.A., Mohammad Y., Mohammad Gholi Mezerji N., Mohammadibakhsh R., Mohammadifard N., Mohammed J.A., Mohammed S., Mohebi F., Mokdad A.H., Molokhia M., Monasta L., Moodley Y., Moore C.E., Moradi G., Moradi M., Moradi-Joo M., Moradi-Lakeh M., Moraga P., Morales L., Moreno Velasquez I., Mosapour A., Mouodi S., Mousavi S.M., Mozaffor M., Muchie K.F., Mulaw G.F., Munro S.B., Muriithi M.K., Murray C.J., Murthy G.V.S., Musa K.I., Mustafa G., Muthupandian S., Nabhan A.F., Naderi M., Nagarajan A.J., Naidoo K.S., Naik G., Najafi F., Nangia V., Nansseu J.R., Nascimento B.R., Nazari J., Ndwandwe D.E., Negoi I., Netsere H.B., Ngunjiri J.W., Nguyen C.T., Nguyen H.L.T., Nguyen T.H., Nigatu D., Nigatu S.G., Ningrum D.N.A., Nnaji C.A., Nojomi M., Nong V.M., Norheim O.F., Noubiap J.J., Nouraei Motlagh S., Oancea B., Ogah O.S., Ogbo F.A., Oh I.-H., Olagunju A.T., Olagunju T.O., Olusanya B.O., Olusanya J.O., Onwujekwe O.E., Oren E., Ortega-Altamirano D.V., Osarenotor O., Osei F.B., Owolabi M.O., P A M., Padubidri J.R., Pakhale S., Patel S.K., Paternina-Caicedo A.J., Pathak A., Patton G.C., Paudel D., Paulos K., Pepito V.C.F., Pereira A., Perico N., Pervaiz A., Pescarini J.M., Piroozi B., Pirsaheb M., Postma M.J., Pourjafar H., Pourmalek F., Pourshams A., Poustchi H., Prada S.I., Prasad N., Preotescu L., Quintana H., Rabiee N., Radfar A., Rafiei A., Rahim F., Rahimi-Movaghar A., Rahimi-Movaghar V., Rahman M.H.U., Rahman M.A., Rahman S., Rajati F., Rana S.M., Ranabhat C.L., Rasella D., Rawaf D.L., Rawaf S., Rawal L., Rawasia W.F., Renjith V., Renzaho A.M.N., Resnikoff S., Reta M.A., Rezaei N., Rezai M.S., Riahi S.M., Ribeiro A.I., Rickard J., Rios-Blancas M., Roever L., Ronfani L., Roro E.M., Ross J.M., Rubagotti E., Rubino S., Saad A.M., Sabde Y.D., Sabour S., Sadeghi E., Safari Y., Safari-Faramani R., Sagar R., Sahebkar A., Sahraian M.A., Sajadi S.M., Salahshoor M.R., Salam N., Salamati P., Salem H., Salem M.R., Salimi Y., Salimzadeh H., Samy A.M., Sanabria J., Santric-Milicevic M.M., Sao Jose B.P., Saraswathy S.Y.I., Sarkar K., Sarker A.R., Sarrafzadegan N., Sartorius B., Sathian B., Sawhney M., Saxena S., Schwebel D.C., Senbeta A.M., Senthilkumaran S., Sepanlou S.G., Servan-Mori E., Shabaninejad H., Shafieesabet A., Shaikh M.A., Shalash A.S., Shallo S.A., Shams-Beyranvand M., Shamsi M.B., Shamsizadeh M., Shannawaz M., Sharafi K., Sharifi H., Shehata H.S., Sheikh A., Shetty B.S.K., Shibuya K., Shiferaw W.S., Shifti D.M., Shigematsu M., Shin J.I., Shiri R., Shirkoohi R., Siabani S., Siddiqi T.J., Silva D.A.S., Singh J.A., Singh N.P., Singh V., Sisay M.M., Skiadaresi E., Sobhiyeh M.R., Sokhan A., Soltani S., Somayaji R., Soofi M., Sorrie M.B., Soyiri I.N., Sreeramareddy C.T., Sudaryanto A., Sufiyan M.B., Suleria H.A.R., Sultana M., Sunguya B.F., Sykes B.L., Tabares-Seisdedos R., Tabuchi T., Tadesse D.B., Tarigan I.U., Tasew A.A., Tefera Y.M., Tekle M.G., Temsah M., Sathish T., Tesfay B.E., Tesfay F.H., Tessema B., Tessema Z.T., Thankappan K.R., Thomas N., Toma A., Topor-Madry R., Tovani-Palone M.R., Traini E., Tran B.X., Tran K.B., Ullah I., Unnikrishnan B., Usman M.S., Uzochukwu B.S.C., Valdez P.R., Varughese S., Violante F.S., Vollmer S., Whawariat F.G., Waheed Y., Wallin M.T., Wang Y., Wang Y.-P., Weaver M., Weji B.G., Weldesamuel G.T., Welgan C.A., Werdecker A., Westerman R., Wiangkham T., Wiysonge C.S., Wolde H.F., Wondafrash D.Z., Wonde T.E., Worku G.T., Wu A.-M., Xu G., Yadollahpour A., Yahyazadeh Jabbari S.H., Yamada T., Yatsuya H., Yeshaneh A., Yilgwan C.S., Yilma M.T., Yip P., Yisma E., Yonemoto N., Yoon S.-J., Younis M.Z., Yousefifard M., Yousof H.-A.S.A., Yu C., Yusefzadeh H., Zadey S., Zaidi Z., Zaman S.B., Zamani M., Zandian H., Zepro N.B., Zerfu T.A., Zhang Y., Zhao X.-J.G., Ziapour A., Zodpey S., Zuniga Y.M.H., Hay S.I., Reiner R.C., Singh A., Wiens K.E., Lindstedt P.A., Blacker B.F., Johnson K.B., Baumann M.M., Schaeffer L.E., Abbastabar H., Abd-Allah F., Abdelalim A., Abdollahpour I., Abegaz K.H., Abejie A.N., Abreu L.G., Abrigo M.R.M., Abualhasan A., Accrombessi M.M.K., Acharya D., Adabi M., Adamu A.A., Adebayo O.M., Adedoyin R.A., Adekanmbi V., Adetokunboh O.O., Adhena B.M., Afarideh M., Ahmad S., Ahmadi K., Ahmed A.E., Ahmed M.B., Ahmed R., Akalu T.Y., Alahdab F., Al-Aly Z., Alam N., Alam S., Alamene G.M., Alanzi T.M., Alcalde-Rabanal J.E., Ali B.A., Alijanzadeh M., Alipour V., Aljunid S.M., Almasi A., Almasi-Hashiani A., Al-Mekhlafi H.M., Altirkawi K.A., Alvis-Guzman N., Alvis-Zakzuk N.J., Amini S., Amit A.M.L., Andrei C.L., Anjomshoa M., Anoushiravani A., Ansari F., Antonio C.A.T., Antony B., Antriyandarti E., Arabloo J., Aref H.M.A., Aremu O., Armoon B., Arora A., Aryal K.K., Arzani A., Asadi-Aliabadi M., Atalay H.T., Athari S.S., Athari S.M., Atre S.R., Ausloos M., Awoke N., Ayala Quintanilla B.P., Ayano G., Ayanore M.A., Aynalem Y.A., Azari S., Azzopardi P.S., Babaee E., Babalola T.K., Badawi A., Bairwa M., Bakkannavar S.M., Balakrishnan S., Bali A.G., Banach M., Banoub J.A.M., Barac A., Barnighausen T.W., Basaleem H., Basu S., Bay V.D., Bayati M., Baye E., Bedi N., Beheshti M., Behzadifar M., Bekele B.B., Belayneh Y.M., Bell M.L., Bennett D.A., Berbada D.A., Bernstein R.S., Bhat A.G., Bhattacharyya K., Bhattarai S., Bhaumik S., Bhutta Z.A., Bijani A., Bikbov B., Birihane B.M., Biswas R.K., Bohlouli S., Bojia H.A., Boufous S., Brady O.J., Bragazzi N.L., Briko A.N., Briko N.I., Britton G.B., Burugina Nagaraja S., Busse R., Butt Z.A., Camera L.A., Campos-Nonato I.R., Cano J., Car J., Cardenas R., Carvalho F., Castaneda-Orjuela C.A., Castro F., Chanie W.F., Chatterjee P., Chattu V.K., Chichiabellu T.Y., Chin K.L., Christopher D.J., Chu D.-T., Cormier N.M., Costa V.M., Culquichicon C., Daba M.S., Damiani G., Dandona L., Dandona R., Dang A.K., Darwesh A.M., Darwish A.H., Daryani A., Das J.K., Das Gupta R.D., Dash A.P., Davey G., Davila-Cervantes C.A., Davis A.C., Davitoiu D.V., De la Hoz F.P., Demis A.B., Demissie D.B., Demissie G.D., Demoz G.T., Denova-Gutierrez E., Deribe K., Desalew A., Deshpande A., Dharmaratne S.D., Dhillon P., Dhimal M., Dhungana G.P., Diaz D., Dipeolu I.O., Djalalinia S., Doyle K.E., Dubljanin E., Duko B., Duraes A.R., Ebrahimi Kalan M., Edinur H.A., Effiong A., Eftekhari A., El Nahas N., El Sayed I., El Sayed Zaki M., El Tantawi M., Elema T.B., Elhabashy H.R., El-Jaafary S.I., Elkout H., Elsharkawy A., Elyazar I.R.F., Endalamaw A., Endalew D.A., Eskandarieh S., Esteghamati A., Esteghamati S., Etemadi A., Ezekannagha O., Fareed M., Faridnia R., Farzadfar F., Fazlzadeh M., Feigin V.L., Fereshtehnejad S.-M., Fernandes E., Filip I., Fischer F., Foigt N.A., Folayan M.O., Foroutan M., Franklin R.C., Fukumoto T., Gad M.M., Gayesa R.T., Gebre T., Gebremedhin K.B., Gebremeskel G.G., Gesesew H.A., Gezae K.E., Ghadiri K., Ghashghaee A., Ghimire P.R., Gill P.S., Gill T.K., Ginindza T.G., Gomes N.G., Gopalani S.V., Goulart A.C., Goulart B.N.G., Grada A., Gubari M.I.M., Gugnani H.C., Guido D., Guimaraes R.A., Guo Y., Gupta R., Hafezi-Nejad N., Haile D.H., Hailu G.B., Haj-Mirzaian A., Hamadeh R.R., Hamidi S., Handiso D.W., Haririan H., Hariyani N., Hasaballah A.I., Hasan M.M., Hasanpoor E., Hasanzadeh A., Hassankhani H., Hassen H.Y., Hegazy M.I., Heibati B., Heidari B., Hendrie D., Henry N.J., Herteliu C., Heydarpour F., Hidru H.D.D., Hird T.R., Hoang C.L., Homaie Rad E.H., Hoogar P., Hoseini M., Hossain N., Hosseini M., Hosseinzadeh M., Househ M., Hsairi M., Hu G., Hussen M.M., Ibitoye S.E., Igumbor E.U., Ilesanmi O.S., Ilic M.D., Imani-Nasab M.H., Iqbal U., Irvani S.S.N., Islam S.M.S., Iwu C.J., Izadi N., Jaca A., Jahanmehr N., Jakovljevic M., Jalali A., Jayatilleke A.U., Jha R.P., Jha V., Ji J.S., Jonas J.B., Jozwiak J.J., Kabir A., Kabir Z., Kahsay A., Kalani H., Kanchan T., Karami Matin B., Karch A., Karim M.A., Karimi-Sari Surendra Karki H., Kasaeian A., Kasahun G.G., Kasahun Y.C., Kasaye H.K., Kassa G.G., Kassa G.M., Kayode G.A., Kazemi Karyani A., Kebede M.M., Keiyoro P.N., Kelbore A.G., Kengne A.P., Ketema D.B., Khader Y.S., Khafaie M.A., Khalid N., Khalilov R., Khan E.A., Khan J., Khan M.N., Khan M.S., Khatab K., Khater A.M., Khater M.M., Khayamzadeh M., Khazaei M., Khazaei S., Khosravi M.H., Khubchandani J., Kiadaliri A., Kim Y.J., Kimokoti R.W., Kisa A., Kisa S., Kissoon N., Shivakumar K.M., Kochhar S., Kolola T., Komaki H., Kosen S., Koul P.A., Koyanagi A., Kraemer M.U.G., Krishan K., Kugbey N., Kumar G.A., Kumar M., Kumar P., Kumar V., Kusuma D., La Vecchia C., Lacey B., Lad S.D., Lal D.K., Lam F., Lami F.H., Lamichhane P., Lansingh V.C., Lasrado S., Laxmaiah A., Lee P.H., LeGrand K.E., Leili M., Lenjebo T.L., Leshargie C.T., Levine A.J., Li S., Linn S., Liu S., Lodha R., Longbottom J., Lopez J.C.F., Magdy Abd El Razek H., Magdy Abd El Razek M., Mahadeshwara Prasad DR., Mahasha P.W., Mahotra N.B., Majeed A., Malekzadeh R., Malta D.C., Mamun A.A., Manafi N., Manda A.L., Manohar N.D.D., Mansournia M.A., Mapoma C.C., Maravilla J.C., Martinez G., Martini S., Martins-Melo F.R., Masaka A., Massenburg B.B., Mathur M.R., Mayala B.K., Mazidi M., McAlinden C., Meharie B.G., Mehndiratta M.M., Mehta K.M., Mekonnen T.C., Meles G.G., Memiah P.T.N., Memish Z.A., Mendoza W., Menezes R.G., Mereta S.T., Meretoja T.J., Mestrovic T., Miazgowski B., Mihretie K.M., Miller T.R., Mini G.K., Mirrakhimov E.M., Moazen B., Mohajer B., Mohamadi-Bolbanabad A., Mohammad D.K., Mohammad K.A., Mohammad Y., Mohammad Gholi Mezerji N., Mohammadibakhsh R., Mohammadifard N., Mohammed J.A., Mohammed S., Mohebi F., Mokdad A.H., Molokhia M., Monasta L., Moodley Y., Moore C.E., Moradi G., Moradi M., Moradi-Joo M., Moradi-Lakeh M., Moraga P., Morales L., Moreno Velasquez I., Mosapour A., Mouodi S., Mousavi S.M., Mozaffor M., Muchie K.F., Mulaw G.F., Munro S.B., Muriithi M.K., Murray C.J., Murthy G.V.S., Musa K.I., Mustafa G., Muthupandian S., Nabhan A.F., Naderi M., Nagarajan A.J., Naidoo K.S., Naik G., Najafi F., Nangia V., Nansseu J.R., Nascimento B.R., Nazari J., Ndwandwe D.E., Negoi I., Netsere H.B., Ngunjiri J.W., Nguyen C.T., Nguyen H.L.T., Nguyen T.H., Nigatu D., Nigatu S.G., Ningrum D.N.A., Nnaji C.A., Nojomi M., Nong V.M., Norheim O.F., Noubiap J.J., Nouraei Motlagh S., Oancea B., Ogah O.S., Ogbo F.A., Oh I.-H., Olagunju A.T., Olagunju T.O., Olusanya B.O., Olusanya J.O., Onwujekwe O.E., Oren E., Ortega-Altamirano D.V., Osarenotor O., Osei F.B., Owolabi M.O., P A M., Padubidri J.R., Pakhale S., Patel S.K., Paternina-Caicedo A.J., Pathak A., Patton G.C., Paudel D., Paulos K., Pepito V.C.F., Pereira A., Perico N., Pervaiz A., Pescarini J.M., Piroozi B., Pirsaheb M., Postma M.J., Pourjafar H., Pourmalek F., Pourshams A., Poustchi H., Prada S.I., Prasad N., Preotescu L., Quintana H., Rabiee N., Radfar A., Rafiei A., Rahim F., Rahimi-Movaghar A., Rahimi-Movaghar V., Rahman M.H.U., Rahman M.A., Rahman S., Rajati F., Rana S.M., Ranabhat C.L., Rasella D., Rawaf D.L., Rawaf S., Rawal L., Rawasia W.F., Renjith V., Renzaho A.M.N., Resnikoff S., Reta M.A., Rezaei N., Rezai M.S., Riahi S.M., Ribeiro A.I., Rickard J., Rios-Blancas M., Roever L., Ronfani L., Roro E.M., Ross J.M., Rubagotti E., Rubino S., Saad A.M., Sabde Y.D., Sabour S., Sadeghi E., Safari Y., Safari-Faramani R., Sagar R., Sahebkar A., Sahraian M.A., Sajadi S.M., Salahshoor M.R., Salam N., Salamati P., Salem H., Salem M.R., Salimi Y., Salimzadeh H., Samy A.M., Sanabria J., Santric-Milicevic M.M., Sao Jose B.P., Saraswathy S.Y.I., Sarkar K., Sarker A.R., Sarrafzadegan N., Sartorius B., Sathian B., Sawhney M., Saxena S., Schwebel D.C., Senbeta A.M., Senthilkumaran S., Sepanlou S.G., Servan-Mori E., Shabaninejad H., Shafieesabet A., Shaikh M.A., Shalash A.S., Shallo S.A., Shams-Beyranvand M., Shamsi M.B., Shamsizadeh M., Shannawaz M., Sharafi K., Sharifi H., Shehata H.S., Sheikh A., Shetty B.S.K., Shibuya K., Shiferaw W.S., Shifti D.M., Shigematsu M., Shin J.I., Shiri R., Shirkoohi R., Siabani S., Siddiqi T.J., Silva D.A.S., Singh J.A., Singh N.P., Singh V., Sisay M.M., Skiadaresi E., Sobhiyeh M.R., Sokhan A., Soltani S., Somayaji R., Soofi M., Sorrie M.B., Soyiri I.N., Sreeramareddy C.T., Sudaryanto A., Sufiyan M.B., Suleria H.A.R., Sultana M., Sunguya B.F., Sykes B.L., Tabares-Seisdedos R., Tabuchi T., Tadesse D.B., Tarigan I.U., Tasew A.A., Tefera Y.M., Tekle M.G., and Temsah M.
Abstract: Background: Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative forms of ORT; however, it is unclear whether RHF prevent child mortality. Previous studies have shown considerable variation between countries in ORS and RHF use, but subnational variation is unknown. This study aims to produce high-resolution geospatial estimates of relative and absolute coverage of ORS, RHF, and ORT (use of either ORS or RHF) in LMICs. Method(s): We used a Bayesian geostatistical model including 15 spatial covariates and data from 385 household surveys across 94 LMICs to estimate annual proportions of children younger than 5 years of age with diarrhoea who received ORS or RHF (or both) on continuous continent-wide surfaces in 2000-17, and aggregated results to policy-relevant administrative units. Additionally, we analysed geographical inequality in coverage across administrative units and estimated the number of diarrhoeal deaths averted by increased coverage over the study period. Uncertainty in the mean coverage estimates was calculated by taking 250 draws from the posterior joint distribution of the model and creating uncertainty intervals (UIs) with the 2.5th and 97.5th percentiles of those 250 draws. Finding(s): While ORS use among children with diarrhoea increased in some countries from 2000 to 2017, coverage remained below 50% in the majority (62.6%; 12 417 of 19 823) of second administrative-level units and an estimated 6 519 000 children (95% UI 5 254 000-7 733 000) with diarrhoea were not treated with any form of ORT in 2017. Increases in ORS use corresponded with declines in RHF in many locations, resulting in relatively constant overall ORT co
Published: 2020

12. Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019:a comprehensive demographic analysis for the Global Burden of Disease Study 2019

Author: Wang, H. (Haidong), Abbas, K. M. (Kaja M.), Abbasifard, M. (Mitra), Abbasi-Kangevari, M. (Mohsen), Abbastabar, H. (Hedayat), Abd-Allah, F. (Foad), Abdelalim, A. (Ahmed), Abolhassani, H. (Hassan), Abreu, L. G. (Lucas Guimaraes), Abrigo, M. R. (Michael R. M.), Abushouk, A. I. (Abdelrahman I.), Adabi, M. (Maryam), Adair, T. (Tim), Adebayo, O. M. (Oladimeji M.), Adedeji, I. A. (Isaac Akinkunmi), Adekanmbi, V. (Victor), Adeoye, A. M. (Abiodun Moshood), Adetokunboh, O. O. (Olatunji O.), Advani, S. M. (Shailesh M.), Afshin, A. (Ashkan), Aghaali, M. (Mohammad), Agrawal, A. (Anurag), Ahmadi, K. (Keivan), Ahmadieh, H. (Hamid), Ahmed, M. B. (Muktar Beshir), Al-Aly, Z. (Ziyad), Alam, K. (Khurshid), Alam, T. (Tahiya), Alanezi, F. M. (Fahad Mashhour), Alanzi, T. M. (Turki M.), Alcalde-Rabanal, J. E. (Jacqueline Elizabeth), Ali, M. (Muhammad), Alicandro, G. (Gianfranco), Alijanzadeh, M. (Mehran), Alinia, C. (Cyrus), Alipour, V. (Vahid), Alizade, H. (Hesam), Aljunid, S. M. (Syed Mohamed), Allebeck, P. (Peter), Almadi, M. A. (Majid Abdulrahman Hamad), Almasi-Hashiani, A. (Amir), Al-Mekhlafi, H. M. (Hesham M.), Altirkawi, K. A. (Khalid A.), Alumran, A. K. (Arwa Khalid), Alvis-Guzman, N. (Nelson), Amini-Rarani, M. (Mostafa), Aminorroaya, A. (Arya), Amit, A. M. (Arianna Maever L.), Ancuceanu, R. (Robert), Andrei, C. L. (Catalina Liliana), Androudi, S. (Sofia), Angus, C. (Colin), Anjomshoa, M. (Mina), Ansari, F. (Fereshteh), Ansari, I. (Iman), Ansari-Moghaddam, A. (Alireza), Antonio, C. A. (Carl Abelardo T.), Antony, C. M. (Catherine M.), Anvari, D. (Davood), Appiah, S. C. (Seth Christopher Yaw), Arabloo, J. (Jalal), Arab-Zozani, M. (Morteza), Aravkin, A. Y. (Aleksandr Y.), Aremu, O. (Olatunde), Arnlov, J. (Johan), Aryal, K. K. (Krishna K.), Asadi-Pooya, A. A. (Ali A.), Asgari, S. (Samaneh), Jafarabadi, M. A. (Mohammad Asghari), Atteraya, M. S. (Madhu Sudhan), Ausloos, M. (Marcel), Avila-Burgos, L. (Leticia), Avokpaho, E. F. (Euripide Frinel Gbenato Arthur), Quintanilla, B. P. (Beatriz Paulina Ayala), Ayano, G. (Getinet), Ayanore, M. A. (Martin Amogre), Azarian, G. (Ghasem), Babaee, E. (Ebrahim), Badiye, A. D. (Ashish D.), Bagli, E. (Eleni), Bahrami, M. A. (Mohammad Amin), Bakhtiari, A. (Ahad), Balassyano, S. (Shelly), Banach, M. (Maciej), Banik, P. C. (Palash Chandra), Barker-Collo, S. L. (Suzanne Lyn), Barnighausen, T. W. (Till Winfried), Barzegar, A. (Akbar), Basu, S. (Sanjay), Baune, B. T. (Bernhard T.), Bayati, M. (Mohsen), Bazmandegan, G. (Gholamreza), Bedi, N. (Neeraj), Bell, M. L. (Michellr L.), Bennett, D. A. (Derrick A.), Bensenor, I. M. (Isabela M.), Berhe, K. (Kidanemaryam), Berman, A. E. (Adam E.), Bertolacci, G. J. (Gregory J.), Bhageerathy, R. (Reshmi), Bhala, N. (Neeraj), Bhattacharyya, K. (Krittika), Bhutta, Z. A. (Zulfiqar A.), Bijani, A. (Ali), Biondi, A. (Antonio), Bisanzio, D. (Donal), Bisignano, C. (Catherine), Biswas, R. K. (Raaj Kishore), Bjrge, T. (Tone), Bohlouli, S. (Somayeh), Bohluli, M. (Mehdi), Bolla, S. R. (Srinivasa Rao Rao), Borzi, A. M. (Antonio Maria), Borzouei, S. (Shiva), Brady, O. J. (Oliver J.), Braithwaite, D. (Dejana), Brauer, M. (Michael), Briko, A. N. (Andrey Nikolaevich), Briko, N. I. (Nikolay Ivanovich), Bumgarner, B. R. (Blair R.), Nagaraja, S. B. (Sharath Burugina), Butt, Z. A. (Zahid A.), dos Santos, F. L. (Florentino Luciano Caetano), Cai, T. (Tianji), Callender, C. S. (Charlton S. K. H.), Camera, L. L. (Luis L. A. Alberto), Campos-Nonato, I. R. (Ismael R.), Cardenas, R. (Rosario), Carreras, G. (Giulia), Carrero, J. J. (Juan J.), Carvalho, F. (Felix), Castaldelli-Maia, J. M. (Joao Mauricio), Castelpietra, G. (Giulio), Castro, F. (Franz), Catala-Lopez, F. (Ferran), Cederroth, C. R. (Christopher R.), Cerin, E. (Ester), Chattu, V. K. (Vijay Kumar), Chin, K. L. (Ken Lee), Chu, D.-T. (Dinh-Toi), Ciobanu, L. G. (Liliana G.), Cirillo, M. (Massimo), Comfort, H. (Haley), Costa, V. M. (Vera Marisa), Cowden, R. G. (Richard G.), Cromwell, E. A. (Elizabeth A.), Croneberger, A. J. (Andrew J.), Cunningham, M. (Matthew), Dahlawi, S. M. (Saad M. A.), Damiani, G. (Giovanni), D'Amico, E. (Emanuele), Dandona, L. (Lalit), Dandona, R. (Rakhi), Dargan, P. I. (Paul I.), Darwesh, A. M. (Aso Mohammad), Daryani, A. (Ahmad), Das Gupta, R. (Rajat), das Neves, J. (Jose), Davletov, K. (Kairat), De Leo, D. (Diego), Denova-Gutierrez, E. (Edgar), Deribe, K. (Kebede), Dervenis, N. (Nikolaos), Desai, R. (Rupak), Dhungana, G. P. (Govinda Prasad), da Silva, D. D. (Diana Dias), Diaz, D. (Daniel), Dippenaar, I. N. (Ilse N.), Djalalinia, S. (Shirin), Do, H. T. (Hoa Thi), Dokova, K. (Klara), Doku, D. T. (David Teye), Dorostkar, F. (Fariba), Doshi, C. P. (Chirag P.), Doshmangir, L. (Leila), Doyle, K. E. (Kerrie E.), Dubljanin, E. (Eleonora), Duraes, A. R. (Andre Rodrigues), Edvardsson, D. (David), Effiong, A. (Andem), El Sayed, I. (Iman), El Tantawi, M. (Maha), Elbarazi, I. (Iffat), El-Jaafary, S. I. (Shaimaa I.), Emamian, M. H. (Mohammad Hassan), Eskandarieh, S. (Sharareh), Esmaeilzadeh, F. (Firooz), Estep, K. (Kara), Farahmand, M. (Mohammad), Faraj, A. (Anwar), Fareed, M. (Mohammad), Faridnia, R. (Roghiyeh), Faro, A. (Andre), Farzadfar, F. (Farshad), Fattahi, N. (Nazir), Fazaeli, A. A. (Ali Akbar), Fazlzadeh, M. (Mehdi), Feigin, V. L. (Valery L.), Fereshtehnejad, S.-M. (Seyed-Mohammad), Fernandes, E. (Eduarda), Ferreira, M. L. (Manuela L.), Filip, I. (Irina), Fischer, F. (Florian), Flohr, C. (Carsten), Foigt, N. A. (Nataliya A.), Folayan, M. O. (Morenike Oluwatoyin), Fomenkov, A. A. (Artem Alekseevich), Freitas, M. (Marisa), Fukumoto, T. (Takeshi), Fuller, J. E. (John E.), Furtado, J. M. (Joao M.), Gad, M. M. (Mohamed M.), Gakidou, E. (Emmanuela), Gallus, S. (Silvano), Gebrehiwot, A. M. (Abiyu Mekonnen), Gebremedhin, K. B. (Ketema Bizuwork), Gething, P. W. (Peter W.), Ghamari, F. (Farhad), Ghashghaee, A. (Ahmad), Gholamian, A. (Asadollah), Gilani, S. A. (Syed Amir), Gitimoghaddam, M. (Mojgan), Glushkova, E. V. (Ekaterina Vladimirovna), Gnedovskaya, E. V. (Elena V.), Gopalani, S. V. (Sameer Vali), Goulart, A. C. (Alessandra C.), Gugnani, H. C. (Harish Chander), Guo, Y. (Yuming), Gupta, R. (Rajeev), Gupta, S. S. (Subodh Sharan), Haagsma, J. A. (Juanita A.), Haj-Mirzaian, A. (Arvin), Haj-Mirzaian, A. (Arya), Halvaei, I. (Iman), Hamadeh, R. R. (Randah R.), Abdullah, K. H. (Kanaan Hamagharib), Han, C. (Chieh), Handiso, D. W. (Demelash Woldeyohannes), Hankey, G. J. (Graeme J.), Haririan, H. (Hamidreza), Haro, J. M. (Josep Maria), Hasaballah, A. I. (Ahmed I.), Hassanipour, S. (Soheil), Hassankhani, H. (Hadi), Hay, S. I. (Simon I.), Heibati, B. (Behzad), Heidari-Soureshjani, R. (Reza), Henny, K. (Kiana), Henry, N. J. (Nathaniel J.), Herteliu, C. (Claudiu), Heydarpour, F. (Fatemeh), Hole, M. K. (Michael K.), Hoogar, P. (Praveen), Hosgood, H. D. (H. Dean), Hossain, N. (Naznin), Hosseinzadeh, M. (Mehdi), Hostiuc, M. (Mihaela), Hostiuc, S. (Sorin), Househ, M. (Mowafa), Hoy, D. G. (Damian G.), Hu, G. (Guoqing), Huda, T. M. (Tanvir M.), Ibitoye, S. E. (Segun Emmanuel), Ikuta, K. S. (Kevin S.), Ilesanmi, O. S. (Olayinka Stephen), Ilic, I. M. (Irena M.), Ilic, M. D. (Milena D.), Imani-Nasab, M. H. (Mohammad Hasan), Islam, M. (MdMohaimenul), Iso, H. (Hiroyasu), Iwu, C. J. (Chinwe Juliana), Jaafari, J. (Jalil), Jacobsen, K. H. (Kathryn H.), Jahagirdar, D. (Deepa), Jahanmehr, N. (Nader), Jalali, A. (Amir), Jalilian, F. (Farzad), James, S. L. (Spencer L.), Janjani, H. (Hosna), Jenabi, E. (Ensiyeh), Jha, R. P. (Ravi Prakash), Jha, V. (Vivekanand), Ji, J. S. (John S.), Jonas, J. B. (Jost B.), Joukar, F. (Farahnaz), Jozwiak, J. J. (Jacek Jerzy), Jurisson, M. (Mikk), Kabir, Z. (Zubair), Kalani, H. (Hamed), Kalankesh, L. R. (Leila R.), Kamiab, Z. (Zahra), Kanchan, T. (Tanuj), Kapoor, N. (Neeti), Karch, A. (Andre), Karimi, S. E. (Salah Eddin), Karimi, S. A. (Seyed Asaad), Kassebaum, N. J. (Nicholas J.), Katikireddi, S. V. (Srinivasa Vittal), Kawakami, N. (Norito), Kayode, G. A. (Gbenga A.), Keiyoro, P. N. (Peter Njenga), Keller, C. (Cathleen), Khader, Y. S. (Yousef Saleh), Khalid, N. (Nauman), Khan, E. A. (Ejaz Ahmad), Khan, M. (Maseer), Khang, Y.-H. (Young-Ho), Khater, A. M. (Amir M.), Khater, M. M. (Mona M.), Khazaei, S. (Salman), Khazaie, H. (Habibolah), Khodayari, M. T. (Mohammad Taghi), Khubchandani, J. (Jagdish), Kianipour, N. (Neda), Kim, C.-i. (Cho-il), Kim, Y.-E. (Young-Eun), Kim, Y. J. (Yun Jin), Kinfu, Y. (Yohannes), Kisa, A. (Adnan), Kisa, S. (Sezer), Kissimova-Skarbek, K. (Katarzyna), Kivimaki, M. (Mika), Komaki, H. (Hamidreza), Kopec, J. A. (Jacek A.), Kosen, S. (Soewarta), Koul, P. A. (Parvaiz A.), Koyanagi, A. (Ai), Kravchenko, M. A. (Michael A.), Krishan, K. (Kewal), Krohn, K. J. (Kris J.), Defo, B. K. (Barthelemy Kuate), Kumar, G. A. (G. Anil), Kumar, M. (Manasi), Kumar, P. (Pushpendra), Kumar, V. (Vivek), Kusuma, D. (Dian), Kyu, H. H. (Hmwe Hmwe), La Vecchia, C. (Carlo), Lacey, B. (Ben), Lal, D. K. (Dharmesh Kumar), Lalloo, R. (Ratilal), Lami, F. H. (Faris Hasan), Lansky, S. (Sonia), Larson, S. L. (Samantha Leigh), Larsson, A. O. (Anders O.), Lasrado, S. (Savita), Lassi, Z. S. (Zohra S.), Lazarus, J. V. (Jeffrey V.), Lee, P. H. (Paul H.), Lee, S. W. (Shaun Wen Huey), Leever, A. T. (Andrew T.), LeGrand, K. E. (Kate E.), Leonardi, M. (Matilde), Li, S. (Shanshan), Lim, L.-L. (Lee-Ling), Lim, S. S. (Stephen S.), Linn, S. (Shai), Lodha, R. (Rakesh), Logroscino, G. (Giancarlo), Lopez, A. D. (Alan D.), Lopukhov, P. D. (Platon D.), Lotufo, P. A. (Paulo A.), Lozano, R. (Rafael), Lu, A. (Alton), Lunevicius, R. (Raimundas), Madadin, M. (Mohammed), Maddison, E. R. (Emilie R.), Abd El Razek, H. M. (Hassan Magdy), Abd El Razek, M. M. (Muhammed Magdy), Mahasha, P. W. (Phetole Walter), Mahdavi, M. M. (Mokhtar Mahdavi), Malekzadeh, R. (Reza), Mamun, A. A. (Abdullah A.), Manafi, N. (Navid), Mansour-Ghanaei, F. (Fariborz), Mansouri, B. (Borhan), Mansournia, M. A. (Mohammad Ali), Mapoma, C. C. (Chabila Christopher), Martini, S. (Santi), Martins-Melo, F. R. (Francisco Rogerlandio), Masaka, A. (Anthony), Mastrogiacomo, C. I. (Claudia I.), Mathur, M. R. (Manu Raj), May, E. A. (Erin A.), McAlinden, C. (Colm), McGrath, J. J. (John J.), McKee, M. (Martin), Mehndiratta, M. M. (Man Mohan), Mehri, F. (Fereshteh), Mehta, K. M. (Kala M.), Meitei, W. B. (Wahengbam Bigyananda), Memiah, P. T. (Peter T. N.), Mendoza, W. (Walter), Menezes, R. G. (Ritesh G.), Mengesha, E. W. (Endalkachew Worku), Mensah, G. A. (George A.), Meretoja, A. (Atte), Meretoja, T. J. (Tuomo J.), Mestrovic, T. (Tomislav), Michalek, I. M. (Irmina Maria), Mihretie, K. M. (Kebadnew Mulatu), Miller, T. R. (Ted R.), Mills, E. J. (Edward J.), Milne, G. J. (George J.), Mirrakhimov, E. M. (Erkin M.), Mirzaei, H. (Hamed), Mirzaei, M. (Maryam), Mirzaei-Alavijeh, M. (Mehdi), Misganaw, A. T. (Awoke Temesgen), Moazen, B. (Babak), Moghadaszadeh, M. (Masoud), Mohamadi, E. (Efat), Mohammad, D. K. (Dara K.), Mohammad, Y. (Yousef), Mezerji, N. M. (Naser Mohammad Gholi), Mohammadbeigi, A. (Abolfazl), Mohammadian-Hafshejani, A. (Abdollah), Mohammadpourhodki, R. (Reza), Mohammed, H. (Hussen), Mohammed, S. (Shafiu), Mohebi, F. (Farnam), Bandpei, M. A. (Mohammad A. Mohseni), Mokari, A. (Amin), Mokdad, A. H. (Ali H.), Momen, N. C. (Natalie C.), Monasta, L. (Lorenzo), Mooney, M. D. (Meghan D.), Moradi, G. (Ghobad), Moradi, M. (Masoud), Moradi-Joo, M. (Mohammad), Moradi-Lakeh, M. (Maziar), Moradzadeh, R. (Rahmatollah), Moraga, P. (Paula), Velasquez, I. M. (Ilais Moreno), Morgado-da-Costa, J. (Joana), Morrison, S. D. (Shane Douglas), Mosser, J. F. (Jonathan F.), Mouodi, S. (Simin), Mousavi, S. M. (Seyyed Meysam), Khaneghah, A. M. (Amin Mousavi), Mueller, U. O. (Ulrich Otto), Musa, K. I. (Kamarul Imran), Muthupandian, S. (Saravanan), Nabavizadeh, B. (Behnam), Naderi, M. (Mehdi), Nagarajan, A. J. (Ahamarshan Jayaraman), Naghavi, M. (Mohsen), Naghshtabrizi, B. (Behshad), Naik, G. (Gurudatta), Najafi, F. (Farid), Nangia, V. (Vinay), Nansseu, J. R. (Jobert Richie), Ndwandwe, D. E. (Duduzile Edith), Negoi, I. (Ionut), Negoi, R. I. (Ruxandra Irina), Ngunjiri, J. W. (Josephine W.), Nguyen, H. L. (Huong Lan Thi), Nguyen, T. H. (Trang Huyen), Nigatu, Y. T. (Yeshambel T.), Nikbakhsh, R. (Rajan), Nikpoor, A. R. (Amin Reza), Nixon, M. R. (Molly R.), Nnaji, C. A. (Chukwudi A.), Nomura, S. (Shuhei), Noubiap, J. J. (Jean Jacques), Motlagh, S. N. (Soraya Nouraei), Nowak, C. (Christoph), Otoiu, A. (Adrian), Odell, C. M. (Christopher M.), Oh, I.-H. (In-Hwan), Oladnabi, M. (Morteza), Olagunju, A. T. (Andrew T.), Olusanya, B. O. (Bolajoko Olubukunola), Olusanya, J. O. (Jacob Olusegun), Bali, A. O. (Ahmed Omar), Ong, K. L. (Kanyin L.), Onwujekwe, O. E. (Obinna E.), Ortiz, A. (Alberto), Otstavnov, N. (Nikita), Otstavnov, S. S. (Stanislav S.), Overland, S. (Simon), Owolabi, M. O. (Mayowa O.), Mahesh, P. A. (P. A.), Padubidri, J. R. (Jagadish Rao), Pakshir, K. (Keyvan), Palladino, R. (Raffaele), Pana, A. (Adrian), Panda-Jonas, S. (Songhomitra), Park, J. (James), Pasupula, D. K. (Deepak Kumar), Patel, J. R. (Jenil R.), Patel, S. K. (Sangram Kishor), Patton, G. C. (George C.), Paulson, K. R. (Katherine R.), Toroudi, H. P. (Hamidreza Pazoki), Pease, S. A. (Spencer A.), Peden, A. E. (Amy E.), Pepito, V. C. (Veincent Christian Filipino), Peprah, E. K. (Emmanuel K.), Pereira, A. (Alexandre), Pereira, D. M. (David M.), Perico, N. (Norberto), Pigott, D. M. (David M.), Pilgrim, T. (Thomas), Pilz, T. M. (Tessa M.), Piradov, M. A. (Michael A.), Pirsaheb, M. (Meghdad), Pokhrel, K. N. (Khem Narayan), Postma, M. J. (Maarten J.), Pourjafar, H. (Hadi), Pourmalek, F. (Farshad), Pourshams, A. (Akram), Poznanska, A. (Anna), Prada, S. I. (Sergio I.), Prakash, S. (Sanjay), Preotescu, L. (Liliana), Syed, Z. Q. (Zahiruddin Quazi), Rabiee, M. (Mohammad), Rabiee, N. (Navid), Radfar, A. (Amir), Rafiei, A. (Alireza), Raggi, A. (Alberto), Rahman, M. A. (Muhammad Aziz), Rajabpour-Sanati, A. (Ali), Ram, P. (Pradhum), Ranabhat, C. L. (Chhabi Lal), Rao, S. J. (Sowmya J.), Rasella, D. (Davide), Rashedi, V. (Vahid), Rastogi, P. (Prateek), Rathi, P. (Priya), Rawal, L. (Lal), Remuzzi, G. (Giuseppe), Renjith, V. (Vishnu), Renzaho, A. M. (Andre M. N.), Resnikoff, S. (Serge), Rezaei, N. (Nima), Rezai, M. s. (Mohammad sadegh), Rezapour, A. (Aziz), Rickard, J. (Jennifer), Roever, L. (Leonardo), Ronfani, L. (Luca), Roshandel, G. (Gholamreza), Rostamian, M. (Morteza), Rubagotti, E. (Enrico), Rwegerera, G. M. (Godfrey M.), Sabour, S. (Siamak), Saddik, B. (Basema), Sadeghi, E. (Ehsan), Sadeghi, M. (Masoumeh), Moghaddam, S. S. (Sahar Saeedi), Safari, Y. (Yahya), Safi, S. (Sare), Safiri, S. (Saeid), Sagar, R. (Rajesh), Sahebkar, A. (Amirhossein), Sahraian, M. A. (Mohammad Ali), Sajadi, S. M. (S. Mohammad), Salahshoor, M. R. (Mohammad Reza), Salama, J. S. (Joseph S.), Salamati, P. (Payman), Salem, M. R. (Marwa R. Rashad), Salimi, Y. (Yahya), Salomon, J. A. (Joshua A.), Salz, I. (Inbal), Samad, Z. (Zainab), Samy, A. M. (Abdallah M.), Sanabria, J. (Juan), Santric-Milicevic, M. M. (Milena M.), Saraswathy, S. Y. (Sivan Yegnanarayana Iyer), Sartorius, B. (Benn), Sarveazad, A. (Arash), Sathian, B. (Brijesh), Sathish, T. (Thirunavukkarasu), Sattin, D. (Davide), Saylan, M. (Mete), Schaeffer, L. E. (Lauren E.), Schiavolin, S. (Silvia), Schwebel, D. C. (David C.), Schwendicke, F. (Falk), Sekerija, M. (Mario), Senbeta, A. M. (Anbissa Muleta), Senthilkumaran, S. (Subramanian), Sepanlou, S. G. (Sadaf G.), Servan-Mori, E. (Edson), Shabani, M. (Mahsima), Shahabi, S. (Saeed), Shahbaz, M. (Mohammad), Shaheen, A. A. (Amira A.), Shaikh, M. A. (Masood Ali), Shalash, A. S. (Ali S.), Shams-Beyranvand, M. (Mehran), Shamsi, M. (MohammadBagher), Shamsizadeh, M. (Morteza), Shannawaz, M. (Mohammed), Sharafi, K. (Kiomars), Sharafi, Z. (Zeinab), Sharara, F. (Fablina), Sharma, R. (Rajesh), Shaw, D. H. (David H.), Sheikh, A. (Aziz), Il Shin, J. (Jae), Shiri, R. (Rahman), Shrime, M. G. (Mark G.), Shuval, K. (Kerem), Siabani, S. (Soraya), Sigfusdottir, I. D. (Inga Dora), Sigurvinsdottir, R. (Rannveig), Silva, D. A. (Diego Augusto Santos), Simonetti, B. (Biagio), Simpson, K. E. (Kyle E.), Singh, J. A. (Jasvinder A.), Skiadaresi, E. (Eirini), Skryabin, V. Y. (Valentin Yurievich), Soheili, A. (Amin), Sokhan, A. (Anton), Sorensen, R. J. (Reed J. D.), Soriano, J. B. (Joan B.), Sorrie, M. B. (Muluken Bekele), Soyiri, I. N. (Ireneous N.), Spurlock, E. E. (Emma Elizabeth), Sreeramareddy, C. T. (Chandrashekhar T.), Stockfelt, L. (Leo), Stokes, M. A. (Mark A.), Stubbs, J. L. (Jacob L.), Sudaryanto, A. (Agus), Sufiyan, M. B. (Mu'awiyyah Babale), Abdulkader, R. S. (Rizwan Suliankatchi), Sykes, B. L. (Bryan L.), Tabares-Seisdedos, R. (Rafael), Tabb, K. M. (Karen M.), Tadakamadla, S. K. (Santosh Kumar), Taherkhani, A. (Amir), Tang, M. (Muming), Taveira, N. (Nuno), Taylor, H. J. (Heather Jean), Teagle, W. L. (Whitney L.), Tehrani-Banihashemi, A. (Arash), Teklehaimanot, B. F. (Berhane Fseha), Tessema, Z. T. (Zemenu Tadesse), Thankappan, K. R. (Kavumpurathu Raman), Thomas, N. (Nihal), Thrift, A. G. (Amanda G.), Titova, M. V. (Mariya Vladimirovna), Tohidinik, H. R. (Hamid Reza), Tonelli, M. (Marcello), Topor-Madry, R. (Roman), Topouzis, F. (Fotis), Tovani-Palone, M. R. (Marcos Roberto Roberto), Traini, E. (Eugenio), Tran, B. X. (Bach Xuan), Travillian, R. (Ravensara), Trias-Llimos, S. (Sergi), Truelsen, T. C. (Thomas Clement), Car, L. T. (Lorainne Tudor), Unnikrishnan, B. (Bhaskaran), Upadhyay, E. (Era), Vacante, M. (Marco), Vakilian, A. (Alireza), Valdez, P. R. (Pascual R.), Valli, A. (Alessandro), Vardavas, C. (Constantine), Vasankari, T. J. (Tommi Juhani), Vasconcelos, A. M. (Ana Maria Nogales), Vasseghian, Y. (Yasser), Veisani, Y. (Yousef), Venketasubramanian, N. (Narayanaswamy), Vidale, S. (Simone), Violante, F. S. (Francesco S.), Vlassov, V. (Vasily), Vollset, S. E. (Stein Emil), Vos, T. (Theo), Vujcic, I. S. (Isidora S.), Vukovic, A. (Ana), Vukovic, R. (Rade), Waheed, Y. (Yasir), Wallin, M. T. (Mitchell Taylor), Walters, M. K. (Magdalene K.), Wang, H. (Hongbo), Wang, Y.-P. (Yuan-Pang), Watson, S. (Stefanie), Wei, J. (Jingkai), Weiss, J. (Jordan), Weldesamuel, G. T. (Girmay Teklay), Werdecker, A. (Andrea), Westerman, R. (Ronny), Whiteford, H. A. (Harvey A.), Wiangkham, T. (Taweewat), Wiens, K. E. (Kirsten E.), Wijeratne, T. (Tissa), Wiysonge, C. S. (Charles Shey), Wojtyniak, B. (Bogdan), Wolfe, C. D. (Charles D. A.), Wondmieneh, A. B. (Adam Belay), Wool, E. E. (Eve E.), Wu, A.-M. (Ai-Min), Wu, J. (Junjie), Xu, G. (Gelin), Yamada, T. (Tomohide), Yamagishi, K. (Kazumasa), Yano, Y. (Yuichiro), Yaya, S. (Sanni), Yazdi-Feyzabadi, V. (Vahid), Yearwood, J. A. (Jamal A.), Yeheyis, T. Y. (Tomas Y.), Yilgwan, C. S. (Christopher Sabo), Yip, P. (Paul), Yonemoto, N. (Naohiro), Yoon, S.-J. (Seok-Jun), Lebni, J. Y. (Javad Yoosefi), York, H. W. (Hunter W.), Younis, M. Z. (Mustafa Z.), Younker, T. P. (Theodore Patrick), Yousefi, Z. (Zabihollah), Yousefinezhadi, T. (Taraneh), Yousuf, A. Y. (Abdilahi Yousuf), Yusefzadeh, H. (Hasan), Moghadam, T. Z. (Telma Zahirian), Zakzuk, J. (Josefina), Bin Zaman, S. (Sojib), Zamani, M. (Mohammad), Zamanian, M. (Maryam), Zandian, H. (Hamed), Zhang, Z.-J. (Zhi-Jiang), Zheng, P. (Peng), Zhou, M. (Maigeng), Ziapour, A. (Arash), Murray, C. J. (Christopher J. L.), Wang, H. (Haidong), Abbas, K. M. (Kaja M.), Abbasifard, M. (Mitra), Abbasi-Kangevari, M. (Mohsen), Abbastabar, H. (Hedayat), Abd-Allah, F. (Foad), Abdelalim, A. (Ahmed), Abolhassani, H. (Hassan), Abreu, L. G. (Lucas Guimaraes), Abrigo, M. R. (Michael R. M.), Abushouk, A. I. (Abdelrahman I.), Adabi, M. (Maryam), Adair, T. (Tim), Adebayo, O. M. (Oladimeji M.), Adedeji, I. A. (Isaac Akinkunmi), Adekanmbi, V. (Victor), Adeoye, A. M. (Abiodun Moshood), Adetokunboh, O. O. (Olatunji O.), Advani, S. M. (Shailesh M.), Afshin, A. (Ashkan), Aghaali, M. (Mohammad), Agrawal, A. (Anurag), Ahmadi, K. (Keivan), Ahmadieh, H. (Hamid), Ahmed, M. B. (Muktar Beshir), Al-Aly, Z. (Ziyad), Alam, K. (Khurshid), Alam, T. (Tahiya), Alanezi, F. M. (Fahad Mashhour), Alanzi, T. M. (Turki M.), Alcalde-Rabanal, J. E. (Jacqueline Elizabeth), Ali, M. (Muhammad), Alicandro, G. (Gianfranco), Alijanzadeh, M. (Mehran), Alinia, C. (Cyrus), Alipour, V. (Vahid), Alizade, H. (Hesam), Aljunid, S. M. (Syed Mohamed), Allebeck, P. (Peter), Almadi, M. A. (Majid Abdulrahman Hamad), Almasi-Hashiani, A. (Amir), Al-Mekhlafi, H. M. (Hesham M.), Altirkawi, K. A. (Khalid A.), Alumran, A. K. (Arwa Khalid), Alvis-Guzman, N. (Nelson), Amini-Rarani, M. (Mostafa), Aminorroaya, A. (Arya), Amit, A. M. (Arianna Maever L.), Ancuceanu, R. (Robert), Andrei, C. L. (Catalina Liliana), Androudi, S. (Sofia), Angus, C. (Colin), Anjomshoa, M. (Mina), Ansari, F. (Fereshteh), Ansari, I. (Iman), Ansari-Moghaddam, A. (Alireza), Antonio, C. A. (Carl Abelardo T.), Antony, C. M. (Catherine M.), Anvari, D. (Davood), Appiah, S. C. (Seth Christopher Yaw), Arabloo, J. (Jalal), Arab-Zozani, M. (Morteza), Aravkin, A. Y. (Aleksandr Y.), Aremu, O. (Olatunde), Arnlov, J. (Johan), Aryal, K. K. (Krishna K.), Asadi-Pooya, A. A. (Ali A.), Asgari, S. (Samaneh), Jafarabadi, M. A. (Mohammad Asghari), Atteraya, M. S. (Madhu Sudhan), Ausloos, M. (Marcel), Avila-Burgos, L. (Leticia), Avokpaho, E. F. (Euripide Frinel Gbenato Arthur), Quintanilla, B. P. (Beatriz Paulina Ayala), Ayano, G. (Getinet), Ayanore, M. A. (Martin Amogre), Azarian, G. (Ghasem), Babaee, E. (Ebrahim), Badiye, A. D. (Ashish D.), Bagli, E. (Eleni), Bahrami, M. A. (Mohammad Amin), Bakhtiari, A. (Ahad), Balassyano, S. (Shelly), Banach, M. (Maciej), Banik, P. C. (Palash Chandra), Barker-Collo, S. L. (Suzanne Lyn), Barnighausen, T. W. (Till Winfried), Barzegar, A. (Akbar), Basu, S. (Sanjay), Baune, B. T. (Bernhard T.), Bayati, M. (Mohsen), Bazmandegan, G. (Gholamreza), Bedi, N. (Neeraj), Bell, M. L. (Michellr L.), Bennett, D. A. (Derrick A.), Bensenor, I. M. (Isabela M.), Berhe, K. (Kidanemaryam), Berman, A. E. (Adam E.), Bertolacci, G. J. (Gregory J.), Bhageerathy, R. (Reshmi), Bhala, N. (Neeraj), Bhattacharyya, K. (Krittika), Bhutta, Z. A. (Zulfiqar A.), Bijani, A. (Ali), Biondi, A. (Antonio), Bisanzio, D. (Donal), Bisignano, C. (Catherine), Biswas, R. K. (Raaj Kishore), Bjrge, T. (Tone), Bohlouli, S. (Somayeh), Bohluli, M. (Mehdi), Bolla, S. R. (Srinivasa Rao Rao), Borzi, A. M. (Antonio Maria), Borzouei, S. (Shiva), Brady, O. J. (Oliver J.), Braithwaite, D. (Dejana), Brauer, M. (Michael), Briko, A. N. (Andrey Nikolaevich), Briko, N. I. (Nikolay Ivanovich), Bumgarner, B. R. (Blair R.), Nagaraja, S. B. (Sharath Burugina), Butt, Z. A. (Zahid A.), dos Santos, F. L. (Florentino Luciano Caetano), Cai, T. (Tianji), Callender, C. S. (Charlton S. K. H.), Camera, L. L. (Luis L. A. Alberto), Campos-Nonato, I. R. (Ismael R.), Cardenas, R. (Rosario), Carreras, G. (Giulia), Carrero, J. J. (Juan J.), Carvalho, F. (Felix), Castaldelli-Maia, J. M. (Joao Mauricio), Castelpietra, G. (Giulio), Castro, F. (Franz), Catala-Lopez, F. (Ferran), Cederroth, C. R. (Christopher R.), Cerin, E. (Ester), Chattu, V. K. (Vijay Kumar), Chin, K. L. (Ken Lee), Chu, D.-T. (Dinh-Toi), Ciobanu, L. G. (Liliana G.), Cirillo, M. (Massimo), Comfort, H. (Haley), Costa, V. M. (Vera Marisa), Cowden, R. G. (Richard G.), Cromwell, E. A. (Elizabeth A.), Croneberger, A. J. (Andrew J.), Cunningham, M. (Matthew), Dahlawi, S. M. (Saad M. A.), Damiani, G. (Giovanni), D'Amico, E. (Emanuele), Dandona, L. (Lalit), Dandona, R. (Rakhi), Dargan, P. I. (Paul I.), Darwesh, A. M. (Aso Mohammad), Daryani, A. (Ahmad), Das Gupta, R. (Rajat), das Neves, J. (Jose), Davletov, K. (Kairat), De Leo, D. (Diego), Denova-Gutierrez, E. (Edgar), Deribe, K. (Kebede), Dervenis, N. (Nikolaos), Desai, R. (Rupak), Dhungana, G. P. (Govinda Prasad), da Silva, D. D. (Diana Dias), Diaz, D. (Daniel), Dippenaar, I. N. (Ilse N.), Djalalinia, S. (Shirin), Do, H. T. (Hoa Thi), Dokova, K. (Klara), Doku, D. T. (David Teye), Dorostkar, F. (Fariba), Doshi, C. P. (Chirag P.), Doshmangir, L. (Leila), Doyle, K. E. (Kerrie E.), Dubljanin, E. (Eleonora), Duraes, A. R. (Andre Rodrigues), Edvardsson, D. (David), Effiong, A. (Andem), El Sayed, I. (Iman), El Tantawi, M. (Maha), Elbarazi, I. (Iffat), El-Jaafary, S. I. (Shaimaa I.), Emamian, M. H. (Mohammad Hassan), Eskandarieh, S. (Sharareh), Esmaeilzadeh, F. (Firooz), Estep, K. (Kara), Farahmand, M. (Mohammad), Faraj, A. (Anwar), Fareed, M. (Mohammad), Faridnia, R. (Roghiyeh), Faro, A. (Andre), Farzadfar, F. (Farshad), Fattahi, N. (Nazir), Fazaeli, A. A. (Ali Akbar), Fazlzadeh, M. (Mehdi), Feigin, V. L. (Valery L.), Fereshtehnejad, S.-M. (Seyed-Mohammad), Fernandes, E. (Eduarda), Ferreira, M. L. (Manuela L.), Filip, I. (Irina), Fischer, F. (Florian), Flohr, C. (Carsten), Foigt, N. A. (Nataliya A.), Folayan, M. O. (Morenike Oluwatoyin), Fomenkov, A. A. (Artem Alekseevich), Freitas, M. (Marisa), Fukumoto, T. (Takeshi), Fuller, J. E. (John E.), Furtado, J. M. (Joao M.), Gad, M. M. (Mohamed M.), Gakidou, E. (Emmanuela), Gallus, S. (Silvano), Gebrehiwot, A. M. (Abiyu Mekonnen), Gebremedhin, K. B. (Ketema Bizuwork), Gething, P. W. (Peter W.), Ghamari, F. (Farhad), Ghashghaee, A. (Ahmad), Gholamian, A. (Asadollah), Gilani, S. A. (Syed Amir), Gitimoghaddam, M. (Mojgan), Glushkova, E. V. (Ekaterina Vladimirovna), Gnedovskaya, E. V. (Elena V.), Gopalani, S. V. (Sameer Vali), Goulart, A. C. (Alessandra C.), Gugnani, H. C. (Harish Chander), Guo, Y. (Yuming), Gupta, R. (Rajeev), Gupta, S. S. (Subodh Sharan), Haagsma, J. A. (Juanita A.), Haj-Mirzaian, A. (Arvin), Haj-Mirzaian, A. (Arya), Halvaei, I. (Iman), Hamadeh, R. R. (Randah R.), Abdullah, K. H. (Kanaan Hamagharib), Han, C. (Chieh), Handiso, D. W. (Demelash Woldeyohannes), Hankey, G. J. (Graeme J.), Haririan, H. (Hamidreza), Haro, J. M. (Josep Maria), Hasaballah, A. I. (Ahmed I.), Hassanipour, S. (Soheil), Hassankhani, H. (Hadi), Hay, S. I. (Simon I.), Heibati, B. (Behzad), Heidari-Soureshjani, R. (Reza), Henny, K. (Kiana), Henry, N. J. (Nathaniel J.), Herteliu, C. (Claudiu), Heydarpour, F. (Fatemeh), Hole, M. K. (Michael K.), Hoogar, P. (Praveen), Hosgood, H. D. (H. Dean), Hossain, N. (Naznin), Hosseinzadeh, M. (Mehdi), Hostiuc, M. (Mihaela), Hostiuc, S. (Sorin), Househ, M. (Mowafa), Hoy, D. G. (Damian G.), Hu, G. (Guoqing), Huda, T. M. (Tanvir M.), Ibitoye, S. E. (Segun Emmanuel), Ikuta, K. S. (Kevin S.), Ilesanmi, O. S. (Olayinka Stephen), Ilic, I. M. (Irena M.), Ilic, M. D. (Milena D.), Imani-Nasab, M. H. (Mohammad Hasan), Islam, M. (MdMohaimenul), Iso, H. (Hiroyasu), Iwu, C. J. (Chinwe Juliana), Jaafari, J. (Jalil), Jacobsen, K. H. (Kathryn H.), Jahagirdar, D. (Deepa), Jahanmehr, N. (Nader), Jalali, A. (Amir), Jalilian, F. (Farzad), James, S. L. (Spencer L.), Janjani, H. (Hosna), Jenabi, E. (Ensiyeh), Jha, R. P. (Ravi Prakash), Jha, V. (Vivekanand), Ji, J. S. (John S.), Jonas, J. B. (Jost B.), Joukar, F. (Farahnaz), Jozwiak, J. J. (Jacek Jerzy), Jurisson, M. (Mikk), Kabir, Z. (Zubair), Kalani, H. (Hamed), Kalankesh, L. R. (Leila R.), Kamiab, Z. (Zahra), Kanchan, T. (Tanuj), Kapoor, N. (Neeti), Karch, A. (Andre), Karimi, S. E. (Salah Eddin), Karimi, S. A. (Seyed Asaad), Kassebaum, N. J. (Nicholas J.), Katikireddi, S. V. (Srinivasa Vittal), Kawakami, N. (Norito), Kayode, G. A. (Gbenga A.), Keiyoro, P. N. (Peter Njenga), Keller, C. (Cathleen), Khader, Y. S. (Yousef Saleh), Khalid, N. (Nauman), Khan, E. A. (Ejaz Ahmad), Khan, M. (Maseer), Khang, Y.-H. (Young-Ho), Khater, A. M. (Amir M.), Khater, M. M. (Mona M.), Khazaei, S. (Salman), Khazaie, H. (Habibolah), Khodayari, M. T. (Mohammad Taghi), Khubchandani, J. (Jagdish), Kianipour, N. (Neda), Kim, C.-i. (Cho-il), Kim, Y.-E. (Young-Eun), Kim, Y. J. (Yun Jin), Kinfu, Y. (Yohannes), Kisa, A. (Adnan), Kisa, S. (Sezer), Kissimova-Skarbek, K. (Katarzyna), Kivimaki, M. (Mika), Komaki, H. (Hamidreza), Kopec, J. A. (Jacek A.), Kosen, S. (Soewarta), Koul, P. A. (Parvaiz A.), Koyanagi, A. (Ai), Kravchenko, M. A. (Michael A.), Krishan, K. (Kewal), Krohn, K. J. (Kris J.), Defo, B. K. (Barthelemy Kuate), Kumar, G. A. (G. Anil), Kumar, M. (Manasi), Kumar, P. (Pushpendra), Kumar, V. (Vivek), Kusuma, D. (Dian), Kyu, H. H. (Hmwe Hmwe), La Vecchia, C. (Carlo), Lacey, B. (Ben), Lal, D. K. (Dharmesh Kumar), Lalloo, R. (Ratilal), Lami, F. H. (Faris Hasan), Lansky, S. (Sonia), Larson, S. L. (Samantha Leigh), Larsson, A. O. (Anders O.), Lasrado, S. (Savita), Lassi, Z. S. (Zohra S.), Lazarus, J. V. (Jeffrey V.), Lee, P. H. (Paul H.), Lee, S. W. (Shaun Wen Huey), Leever, A. T. (Andrew T.), LeGrand, K. E. (Kate E.), Leonardi, M. (Matilde), Li, S. (Shanshan), Lim, L.-L. (Lee-Ling), Lim, S. S. (Stephen S.), Linn, S. (Shai), Lodha, R. (Rakesh), Logroscino, G. (Giancarlo), Lopez, A. D. (Alan D.), Lopukhov, P. D. (Platon D.), Lotufo, P. A. (Paulo A.), Lozano, R. (Rafael), Lu, A. (Alton), Lunevicius, R. (Raimundas), Madadin, M. (Mohammed), Maddison, E. R. (Emilie R.), Abd El Razek, H. M. (Hassan Magdy), Abd El Razek, M. M. (Muhammed Magdy), Mahasha, P. W. (Phetole Walter), Mahdavi, M. M. (Mokhtar Mahdavi), Malekzadeh, R. (Reza), Mamun, A. A. (Abdullah A.), Manafi, N. (Navid), Mansour-Ghanaei, F. (Fariborz), Mansouri, B. (Borhan), Mansournia, M. A. (Mohammad Ali), Mapoma, C. C. (Chabila Christopher), Martini, S. (Santi), Martins-Melo, F. R. (Francisco Rogerlandio), Masaka, A. (Anthony), Mastrogiacomo, C. I. (Claudia I.), Mathur, M. R. (Manu Raj), May, E. A. (Erin A.), McAlinden, C. (Colm), McGrath, J. J. (John J.), McKee, M. (Martin), Mehndiratta, M. M. (Man Mohan), Mehri, F. (Fereshteh), Mehta, K. M. (Kala M.), Meitei, W. B. (Wahengbam Bigyananda), Memiah, P. T. (Peter T. N.), Mendoza, W. (Walter), Menezes, R. G. (Ritesh G.), Mengesha, E. W. (Endalkachew Worku), Mensah, G. A. (George A.), Meretoja, A. (Atte), Meretoja, T. J. (Tuomo J.), Mestrovic, T. (Tomislav), Michalek, I. M. (Irmina Maria), Mihretie, K. M. (Kebadnew Mulatu), Miller, T. R. (Ted R.), Mills, E. J. (Edward J.), Milne, G. J. (George J.), Mirrakhimov, E. M. (Erkin M.), Mirzaei, H. (Hamed), Mirzaei, M. (Maryam), Mirzaei-Alavijeh, M. (Mehdi), Misganaw, A. T. (Awoke Temesgen), Moazen, B. (Babak), Moghadaszadeh, M. (Masoud), Mohamadi, E. (Efat), Mohammad, D. K. (Dara K.), Mohammad, Y. (Yousef), Mezerji, N. M. (Naser Mohammad Gholi), Mohammadbeigi, A. (Abolfazl), Mohammadian-Hafshejani, A. (Abdollah), Mohammadpourhodki, R. (Reza), Mohammed, H. (Hussen), Mohammed, S. (Shafiu), Mohebi, F. (Farnam), Bandpei, M. A. (Mohammad A. Mohseni), Mokari, A. (Amin), Mokdad, A. H. (Ali H.), Momen, N. C. (Natalie C.), Monasta, L. (Lorenzo), Mooney, M. D. (Meghan D.), Moradi, G. (Ghobad), Moradi, M. (Masoud), Moradi-Joo, M. (Mohammad), Moradi-Lakeh, M. (Maziar), Moradzadeh, R. (Rahmatollah), Moraga, P. (Paula), Velasquez, I. M. (Ilais Moreno), Morgado-da-Costa, J. (Joana), Morrison, S. D. (Shane Douglas), Mosser, J. F. (Jonathan F.), Mouodi, S. (Simin), Mousavi, S. M. (Seyyed Meysam), Khaneghah, A. M. (Amin Mousavi), Mueller, U. O. (Ulrich Otto), Musa, K. I. (Kamarul Imran), Muthupandian, S. (Saravanan), Nabavizadeh, B. (Behnam), Naderi, M. (Mehdi), Nagarajan, A. J. (Ahamarshan Jayaraman), Naghavi, M. (Mohsen), Naghshtabrizi, B. (Behshad), Naik, G. (Gurudatta), Najafi, F. (Farid), Nangia, V. (Vinay), Nansseu, J. R. (Jobert Richie), Ndwandwe, D. E. (Duduzile Edith), Negoi, I. (Ionut), Negoi, R. I. (Ruxandra Irina), Ngunjiri, J. W. (Josephine W.), Nguyen, H. L. (Huong Lan Thi), Nguyen, T. H. (Trang Huyen), Nigatu, Y. T. (Yeshambel T.), Nikbakhsh, R. (Rajan), Nikpoor, A. R. (Amin Reza), Nixon, M. R. (Molly R.), Nnaji, C. A. (Chukwudi A.), Nomura, S. (Shuhei), Noubiap, J. J. (Jean Jacques), Motlagh, S. N. (Soraya Nouraei), Nowak, C. (Christoph), Otoiu, A. (Adrian), Odell, C. M. (Christopher M.), Oh, I.-H. (In-Hwan), Oladnabi, M. (Morteza), Olagunju, A. T. (Andrew T.), Olusanya, B. O. (Bolajoko Olubukunola), Olusanya, J. O. (Jacob Olusegun), Bali, A. O. (Ahmed Omar), Ong, K. L. (Kanyin L.), Onwujekwe, O. E. (Obinna E.), Ortiz, A. (Alberto), Otstavnov, N. (Nikita), Otstavnov, S. S. (Stanislav S.), Overland, S. (Simon), Owolabi, M. O. (Mayowa O.), Mahesh, P. A. (P. A.), Padubidri, J. R. (Jagadish Rao), Pakshir, K. (Keyvan), Palladino, R. (Raffaele), Pana, A. (Adrian), Panda-Jonas, S. (Songhomitra), Park, J. (James), Pasupula, D. K. (Deepak Kumar), Patel, J. R. (Jenil R.), Patel, S. K. (Sangram Kishor), Patton, G. C. (George C.), Paulson, K. R. (Katherine R.), Toroudi, H. P. (Hamidreza Pazoki), Pease, S. A. (Spencer A.), Peden, A. E. (Amy E.), Pepito, V. C. (Veincent Christian Filipino), Peprah, E. K. (Emmanuel K.), Pereira, A. (Alexandre), Pereira, D. M. (David M.), Perico, N. (Norberto), Pigott, D. M. (David M.), Pilgrim, T. (Thomas), Pilz, T. M. (Tessa M.), Piradov, M. A. (Michael A.), Pirsaheb, M. (Meghdad), Pokhrel, K. N. (Khem Narayan), Postma, M. J. (Maarten J.), Pourjafar, H. (Hadi), Pourmalek, F. (Farshad), Pourshams, A. (Akram), Poznanska, A. (Anna), Prada, S. I. (Sergio I.), Prakash, S. (Sanjay), Preotescu, L. (Liliana), Syed, Z. Q. (Zahiruddin Quazi), Rabiee, M. (Mohammad), Rabiee, N. (Navid), Radfar, A. (Amir), Rafiei, A. (Alireza), Raggi, A. (Alberto), Rahman, M. A. (Muhammad Aziz), Rajabpour-Sanati, A. (Ali), Ram, P. (Pradhum), Ranabhat, C. L. (Chhabi Lal), Rao, S. J. (Sowmya J.), Rasella, D. (Davide), Rashedi, V. (Vahid), Rastogi, P. (Prateek), Rathi, P. (Priya), Rawal, L. (Lal), Remuzzi, G. (Giuseppe), Renjith, V. (Vishnu), Renzaho, A. M. (Andre M. N.), Resnikoff, S. (Serge), Rezaei, N. (Nima), Rezai, M. s. (Mohammad sadegh), Rezapour, A. (Aziz), Rickard, J. (Jennifer), Roever, L. (Leonardo), Ronfani, L. (Luca), Roshandel, G. (Gholamreza), Rostamian, M. (Morteza), Rubagotti, E. (Enrico), Rwegerera, G. M. (Godfrey M.), Sabour, S. (Siamak), Saddik, B. (Basema), Sadeghi, E. (Ehsan), Sadeghi, M. (Masoumeh), Moghaddam, S. S. (Sahar Saeedi), Safari, Y. (Yahya), Safi, S. (Sare), Safiri, S. (Saeid), Sagar, R. (Rajesh), Sahebkar, A. (Amirhossein), Sahraian, M. A. (Mohammad Ali), Sajadi, S. M. (S. Mohammad), Salahshoor, M. R. (Mohammad Reza), Salama, J. S. (Joseph S.), Salamati, P. (Payman), Salem, M. R. (Marwa R. Rashad), Salimi, Y. (Yahya), Salomon, J. A. (Joshua A.), Salz, I. (Inbal), Samad, Z. (Zainab), Samy, A. M. (Abdallah M.), Sanabria, J. (Juan), Santric-Milicevic, M. M. (Milena M.), Saraswathy, S. Y. (Sivan Yegnanarayana Iyer), Sartorius, B. (Benn), Sarveazad, A. (Arash), Sathian, B. (Brijesh), Sathish, T. (Thirunavukkarasu), Sattin, D. (Davide), Saylan, M. (Mete), Schaeffer, L. E. (Lauren E.), Schiavolin, S. (Silvia), Schwebel, D. C. (David C.), Schwendicke, F. (Falk), Sekerija, M. (Mario), Senbeta, A. M. (Anbissa Muleta), Senthilkumaran, S. (Subramanian), Sepanlou, S. G. (Sadaf G.), Servan-Mori, E. (Edson), Shabani, M. (Mahsima), Shahabi, S. (Saeed), Shahbaz, M. (Mohammad), Shaheen, A. A. (Amira A.), Shaikh, M. A. (Masood Ali), Shalash, A. S. (Ali S.), Shams-Beyranvand, M. (Mehran), Shamsi, M. (MohammadBagher), Shamsizadeh, M. (Morteza), Shannawaz, M. (Mohammed), Sharafi, K. (Kiomars), Sharafi, Z. (Zeinab), Sharara, F. (Fablina), Sharma, R. (Rajesh), Shaw, D. H. (David H.), Sheikh, A. (Aziz), Il Shin, J. (Jae), Shiri, R. (Rahman), Shrime, M. G. (Mark G.), Shuval, K. (Kerem), Siabani, S. (Soraya), Sigfusdottir, I. D. (Inga Dora), Sigurvinsdottir, R. (Rannveig), Silva, D. A. (Diego Augusto Santos), Simonetti, B. (Biagio), Simpson, K. E. (Kyle E.), Singh, J. A. (Jasvinder A.), Skiadaresi, E. (Eirini), Skryabin, V. Y. (Valentin Yurievich), Soheili, A. (Amin), Sokhan, A. (Anton), Sorensen, R. J. (Reed J. D.), Soriano, J. B. (Joan B.), Sorrie, M. B. (Muluken Bekele), Soyiri, I. N. (Ireneous N.), Spurlock, E. E. (Emma Elizabeth), Sreeramareddy, C. T. (Chandrashekhar T.), Stockfelt, L. (Leo), Stokes, M. A. (Mark A.), Stubbs, J. L. (Jacob L.), Sudaryanto, A. (Agus), Sufiyan, M. B. (Mu'awiyyah Babale), Abdulkader, R. S. (Rizwan Suliankatchi), Sykes, B. L. (Bryan L.), Tabares-Seisdedos, R. (Rafael), Tabb, K. M. (Karen M.), Tadakamadla, S. K. (Santosh Kumar), Taherkhani, A. (Amir), Tang, M. (Muming), Taveira, N. (Nuno), Taylor, H. J. (Heather Jean), Teagle, W. L. (Whitney L.), Tehrani-Banihashemi, A. (Arash), Teklehaimanot, B. F. (Berhane Fseha), Tessema, Z. T. (Zemenu Tadesse), Thankappan, K. R. (Kavumpurathu Raman), Thomas, N. (Nihal), Thrift, A. G. (Amanda G.), Titova, M. V. (Mariya Vladimirovna), Tohidinik, H. R. (Hamid Reza), Tonelli, M. (Marcello), Topor-Madry, R. (Roman), Topouzis, F. (Fotis), Tovani-Palone, M. R. (Marcos Roberto Roberto), Traini, E. (Eugenio), Tran, B. X. (Bach Xuan), Travillian, R. (Ravensara), Trias-Llimos, S. (Sergi), Truelsen, T. C. (Thomas Clement), Car, L. T. (Lorainne Tudor), Unnikrishnan, B. (Bhaskaran), Upadhyay, E. (Era), Vacante, M. (Marco), Vakilian, A. (Alireza), Valdez, P. R. (Pascual R.), Valli, A. (Alessandro), Vardavas, C. (Constantine), Vasankari, T. J. (Tommi Juhani), Vasconcelos, A. M. (Ana Maria Nogales), Vasseghian, Y. (Yasser), Veisani, Y. (Yousef), Venketasubramanian, N. (Narayanaswamy), Vidale, S. (Simone), Violante, F. S. (Francesco S.), Vlassov, V. (Vasily), Vollset, S. E. (Stein Emil), Vos, T. (Theo), Vujcic, I. S. (Isidora S.), Vukovic, A. (Ana), Vukovic, R. (Rade), Waheed, Y. (Yasir), Wallin, M. T. (Mitchell Taylor), Walters, M. K. (Magdalene K.), Wang, H. (Hongbo), Wang, Y.-P. (Yuan-Pang), Watson, S. (Stefanie), Wei, J. (Jingkai), Weiss, J. (Jordan), Weldesamuel, G. T. (Girmay Teklay), Werdecker, A. (Andrea), Westerman, R. (Ronny), Whiteford, H. A. (Harvey A.), Wiangkham, T. (Taweewat), Wiens, K. E. (Kirsten E.), Wijeratne, T. (Tissa), Wiysonge, C. S. (Charles Shey), Wojtyniak, B. (Bogdan), Wolfe, C. D. (Charles D. A.), Wondmieneh, A. B. (Adam Belay), Wool, E. E. (Eve E.), Wu, A.-M. (Ai-Min), Wu, J. (Junjie), Xu, G. (Gelin), Yamada, T. (Tomohide), Yamagishi, K. (Kazumasa), Yano, Y. (Yuichiro), Yaya, S. (Sanni), Yazdi-Feyzabadi, V. (Vahid), Yearwood, J. A. (Jamal A.), Yeheyis, T. Y. (Tomas Y.), Yilgwan, C. S. (Christopher Sabo), Yip, P. (Paul), Yonemoto, N. (Naohiro), Yoon, S.-J. (Seok-Jun), Lebni, J. Y. (Javad Yoosefi), York, H. W. (Hunter W.), Younis, M. Z. (Mustafa Z.), Younker, T. P. (Theodore Patrick), Yousefi, Z. (Zabihollah), Yousefinezhadi, T. (Taraneh), Yousuf, A. Y. (Abdilahi Yousuf), Yusefzadeh, H. (Hasan), Moghadam, T. Z. (Telma Zahirian), Zakzuk, J. (Josefina), Bin Zaman, S. (Sojib), Zamani, M. (Mohammad), Zamanian, M. (Maryam), Zandian, H. (Hamed), Zhang, Z.-J. (Zhi-Jiang), Zheng, P. (Peng), Zhou, M. (Maigeng), Ziapour, A. (Arash), and Murray, C. J. (Christopher J. L.)
Abstract: Background: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods: 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate age-specific fertility rates for 5-year age groups between ages 15 and 49 years. With extensions to age groups 10–14 and 50–54 years, the total fertility rate (TFR) was then aggregated using the estimated age-specific fertility between ages 10 and 54 years. 7417 sources were used for under-5 mortality estimation and 7355 for adult mortality. ST-GPR was used to synthesise data sources after correction for known biases. Adult mortality was measured as the probability of death between ages 15 and 60 years based on vital registration, sample registration, and sibling histories, and was also estimated using ST-GPR. HIV-free life tables were then estimated using estimates of under-5 and adult mortality rates using a relational model life table system created for GBD, which closely tracks observed age-specific mortality rates from complete vital registration when available. Independent estimates of HIV-specific mortality generated by an epidemiological analysis of HIV prevalence surveys and antenatal clinic serosurveillance and other sources were incorporated into the estimates in countries with large epidemics. Annual and single-year age estimates of net migration and population for each country and territory were generated us
Published: 2020

13. Mapping geographical inequalities in oral rehydration therapy coverage in low-income and middle-income countries, 2000–17

Author: Wiens, K. E. (Kirsten E.), Lindstedt, P. A. (Paulina A.), Blacker, B. F. (Brigette F.), Johnson, K. B. (Kimberly B.), Baumann, M. M. (Mathew M.), Schaeffer, L. E. (Lauren E.), Abbastabar, H. (Hedayat), Abd-Allah, F. (Foad), Abdelalim, A. (Ahmed), Abdollahpour, I. (Ibrahim), Abegaz, K. H. (Kedir Hussein), Abejie, A. N. (Ayenew Negesse), Abreu, L. G. (Lucas Guimaraes), Abrigo, M. R. (Michael R. M.), Abualhasan, A. (Ahmed), Accrombessi, M. M. (Manfred Mario Kokou), Acharya, D. (Dilaram), Adabi, M. (Maryam), Adamu, A. A. (Abdu A.), Adebayo, O. M. (Oladimeji M.), Adedoyin, R. A. (Rufus Adesoji), Adekanmbi, V. (Victor), Adetokunboh, O. O. (Olatunji O.), Adhena, B. M. (Beyene Meressa), Afarideh, M. (Mohsen), Ahmad, S. (Sohail), Ahmadi, K. (Keivan), Ahmed, A. E. (Anwar E.), Ahmed, M. B. (Muktar Beshir), Ahmed, R. (Rushdia), Akalu, T. Y. (Temesgen Yihunie), Alahdab, F. (Fares), Al-Aly, Z. (Ziyad), Alam, N. (Noore), Alam, S. (Samiah), Alamene, G. M. (Genet Melak), Alanzi, T. M. (Turki M.), Alcalde-Rabanal, J. E. (Jacqueline Elizabeth), Ali, B. A. (Beriwan Abdulqadir), Alijanzadeh, M. (Mehran), Alipour, V. (Vahid), Aljunid, S. M. (Syed Mohamed), Almasi, A. (Ali), Almasi-Hashiani, A. (Amir), Al-Mekhlafi, H. M. (Hesham M.), Altirkawi, K. A. (Khalid A.), Alvis-Guzman, N. (Nelson), Alvis-Zakzuk, N. J. (Nelson J.), Amini, S. (Saeed), Amit, A. M. (Arianna Maever L.), Andrei, C. L. (Catalina Liliana), Anjomshoa, M. (Mina), Anoushiravani, A. (Amir), Ansari, F. (Fereshteh), Antonio, C. A. (Carl Abelardo T.), Antony, B. (Benny), Antriyandarti, E. (Ernoiz), Arabloo, J. (Jalal), Aref, H. M. (Hany Mohamed Amin), Aremu, O. (Olatunde), Armoon, B. (Bahram), Arora, A. (Amit), Aryal, K. K. (Krishna K.), Arzani, A. (Afsaneh), Asadi-Aliabadi, M. (Mehran), Atalay, H. T. (Hagos Tasew), Athari, S. S. (Seyyed Shamsadin), Athari, S. M. (Seyyede Masoume), Atre, S. R. (Sachin R.), Ausloos, M. (Marcel), Awoke, N. (Nefsu), Quintanilla, B. P. (Beatriz Paulina Ayala), Ayano, G. (Getinet), Ayanore, M. A. (Martin Amogre), Aynalem, Y. A. (Yared Asmare), Azari, S. (Samad), Azzopardi, P. S. (Peter S.), Babaee, E. (Ebrahim), Babalola, T. K. (Tesleem Kayode), Badawi, A. (Alaa), Bairwa, M. (Mohan), Bakkannavar, S. M. (Shankar M.), Balakrishnan, S. (Senthilkumar), Bali, A. G. (Ayele Geleto), Banach, M. (Maciej), Banoub, J. A. (Joseph Adel Mattar), Barac, A. (Aleksandra), Barnighausen, T. W. (Till Winfried), Basaleem, H. (Huda), Basu, S. (Sanjay), Bay, V. D. (Vo Dinh), Bayati, M. (Mohsen), Baye, E. (Estifanos), Bedi, N. (Neeraj), Beheshti, M. (Mahya), Behzadifar, M. (Masoud), Behzadifar, M. (Meysam), Bekele, B. B. (Bayu Begashaw), Belayneh, Y. M. (Yaschilal Muche), Bell, M. L. (Michelle L.), Bennett, D. A. (Derrick A.), Berbada, D. A. (Dessalegn Ajema), Bernstein, R. S. (Robert S.), Bhat, A. G. (Anusha Ganapati), Bhattacharyya, K. (Krittika), Bhattarai, S. (Suraj), Bhaumik, S. (Soumyadeep), Bhutta, Z. A. (Zulfiqar A.), Bijani, A. (Ali), Bikbov, B. (Boris), Birihane, B. M. (Binyam Minuye), Biswas, R. K. (Raaj Kishore), Bohlouli, S. (Somayeh), Bojia, H. A. (Hunduma Amensisa), Boufous, S. (Soufiane), Brady, O. J. (Oliver J.), Bragazzi, N. L. (Nicola Luigi), Briko, A. N. (Andrey Nikolaevich), Briko, N. I. (Nikolay Ivanovich), Britton, G. B. (Gabrielle B.), Nagaraja, S. B. (Sharath Burugina), Busse, R. (Reinhard), Butt, Z. A. (Zahid A.), Camera, L. A. (Luis Alberto), Campos-Nonato, I. R. (Ismael R.), Cano, J. (Jorge), Car, J. (Josip), Cardenas, R. (Rosario), Carvalho, F. (Felix), Castaneda-Orjuela, C. A. (Carlos A.), Castro, F. (Franz), Chanie, W. F. (Wagaye Fentahun), Chatterjee, P. (Pranab), Chattu, V. K. (Vijay Kumar), Chichiabellu, T. Y. (Tesfaye Yitna), Chin, K. L. (Ken Lee), Christopher, D. J. (Devasahayam J.), Chu, D.-T. (Dinh-Toi), Cormier, N. M. (Natalie Maria), Costa, V. M. (Vera Marisa), Culquichicon, C. (Carlos), Daba, M. S. (Matiwos Soboka), Damiani, G. (Giovanni), Dandona, L. (Lalit), Dandona, R. (Rakhi), Dang, A. K. (Anh Kim), Darwesh, A. M. (Aso Mohammad), Darwish, A. H. (Amira Hamed), Daryani, A. (Ahmad), Das, J. K. (Jai K.), Das Gupta, R. (Rajat), Dash, A. P. (Aditya Prasad), Davey, G. (Gail), Davila-Cervantes, C. A. (Claudio Alberto), Davis, A. C. (Adrian C.), Davitoiu, D. V. (Dragos Virgil), De la Hoz, F. P. (Fernando Pio), Demis, A. B. (Asmamaw Bizuneh), Demissie, D. B. (Dereje Bayissa), Demissie, G. D. (Getu Debalkie), Demoz, G. T. (Gebre Teklemariam), Denova-Gutierrez, E. (Edgar), Deribe, K. (Kebede), Desalew, A. (Assefa), Deshpande, A. (Aniruddha), Dharmaratne, S. D. (Samath Dhamminda), Dhillon, P. (Preeti), Dhimal, M. (Meghnath), Dhungana, G. P. (Govinda Prasad), Diaz, D. (Daniel), Dipeolu, I. O. (Isaac Oluwafemi), Djalalinia, S. (Shirin), Doyle, K. E. (Kerrie E.), Dubljanin, E. (Eleonora), Duko, B. (Bereket), Duraes, A. R. (Andre Rodrigues), Kalan, M. E. (Mohammad Ebrahimi), Edinur, H. A. (Hisham Atan), Effiong, A. (Andem), Eftekhari, A. (Aziz), El Nahas, N. (Nevine), El Sayed, I. (Iman), Zaki, M. E. (Maysaa El Sayed), El Tantawi, M. (Maha), Elema, T. B. (Teshome Bekele), Elhabashy, H. R. (Hala Rashad), El-Jaafary, S. I. (Shaimaa I.), Elkout, H. (Hajer), Elsharkawy, A. (Aisha), Elyazar, I. R. (Iqbal R. F.), Endalamaw, A. (Aklilu), Endalew, D. A. (Daniel Adane), Eskandarieh, S. (Sharareh), Esteghamati, A. (Alireza), Esteghamati, S. (Sadaf), Etemadi, A. (Arash), Ezekannagha, O. (Oluchi), Fareed, M. (Mohammad), Faridnia, R. (Roghiyeh), Farzadfar, F. (Farshad), Fazlzadeh, M. (Mehdi), Feigin, V. L. (Valery L.), Fereshtehnejad, S.-M. (Seyed-Mohammad), Fernandes, E. (Eduarda), Filip, I. (Irina), Fischer, F. (Florian), Foigt, N. A. (Nataliya A.), Folayan, M. O. (Morenike Oluwatoyin), Foroutan, M. (Masoud), Franklin, R. C. (Richard Charles), Fukumoto, T. (Takeshi), Gad, M. M. (Mohamed M.), Gayesa, R. T. (Reta Tsegaye), Gebre, T. (Teshome), Gebremedhin, K. B. (Ketema Bizuwork), Gebremeskel, G. G. (Gebreamlak Gebremedhn), Gesesew, H. A. (Hailay Abrha), Gezae, K. E. (Kebede Embaye), Ghadiri, K. (Keyghobad), Ghashghaee, A. (Ahmad), Ghimire, P. R. (Pramesh Raj), Gill, P. S. (Paramjit Singh), Gill, T. K. (Tiffany K.), Ginindza, T. G. (Themba G.), Gomes, N. G. (Nelson G. M.), Gopalani, S. V. (Sameer Vali), Goulart, A. C. (Alessandra C.), Goulart, B. N. (Barbara Niegia Garcia), Grada, A. (Ayman), Gubari, M. I. (Mohammed Ibrahim Mohialdeen), Gugnani, H. C. (Harish Chander), Guido, D. (Davide), Guimaraes, R. A. (Rafael Alves), Guo, Y. (Yuming), Gupta, R. (Rajeev), Hafezi-Nejad, N. (Nima), Haile, D. H. (Dessalegn H.), Hailu, G. B. (Gessessew Bugssa), Haj-Mirzaian, A. (Arvin), Haj-Mirzaian, A. (Arya), Hamadeh, R. R. (Randah R.), Hamidi, S. (Samer), Handiso, D. W. (Demelash Woldeyohannes), Haririan, H. (Hamidreza), Hariyani, N. (Ninuk), Hasaballah, A. I. (Ahmed I.), Hasan, M. M. (Md Mehedi), Hasanpoor, E. (Edris), Hasanzadeh, A. (Amir), Hassankhani, H. (Hadi), Hassen, H. Y. (Hamid Yimam), Hegazy, M. I. (Mohamed I.), Heibati, B. (Behzad), Heidari, B. (Behnam), Hendrie, D. (Delia), Henry, N. J. (Nathaniel J.), Herteliu, C. (Claudiu), Heydarpour, F. (Fatemeh), de Hidru, H. D. (Hagos Degefa), Hird, T. R. (Thomas R.), Hoang, C. L. (Chi Linh), Rad, E. H. (Enayatollah Homaie), Hoogar, P. (Praveen), Hoseini, M. (Mohammad), Hossain, N. (Naznin), Hosseini, M. (Mostafa), Hosseinzadeh, M. (Mehdi), Househ, M. (Mowafa), Hsairi, M. (Mohamed), Hu, G. (Guoqing), Hussen, M. M. (Mohammedaman Mama), Ibitoye, S. E. (Segun Emmanuel), Igumbor, E. U. (Ehimario U.), Ilesanmi, O. S. (Olayinka Stephen), Ilic, M. D. (Milena D.), Imani-Nasab, M. H. (Mohammad Hasan), Iqbal, U. (Usman), Irvani, S. S. (Seyed Sina Naghibi), Islam, S. M. (Sheikh Mohammed Shariful), Iwu, C. J. (Chinwe Juliana), Izadi, N. (Neda), Jaca, A. (Anelisa), Jahanmehr, N. (Nader), Jakovljevic, M. (Mihajlo), Jalali, A. (Amir), Jayatilleke, A. U. (Achala Upendra), Jha, R. P. (Ravi Prakash), Jha, V. (Vivekanand), Ji, J. S. (John S.), Jonas, J. B. (Jost B.), Jozwiak, J. J. (Jacek Jerzy), Kabir, A. (Ali), Kabir, Z. (Zubair), Kahsay, A. (Amaha), Kalani, H. (Hamed), Kanchan, T. (Tanuj), Matin, B. K. (Behzad Karami), Karch, A. (Andre), Karim, M. A. (Mohd Anisul), Karki, H. K. (Hamidreza Karimi-Sari Surendra), Kasaeian, A. (Amir), Kasahun, G. G. (Gebremicheal Gebreslassie), Kasahun, Y. C. (Yawukal Chane), Kasaye, H. K. (Habtamu Kebebe), Kassa, G. G. (Gebrehiwot G.), Kassa, G. M. (Getachew Mullu), Kayode, G. A. (Gbenga A.), Karyani, A. K. (Ali Kazemi), Kebede, M. M. (Mihiretu M.), Keiyoro, P. N. (Peter Njenga), Kelbore, A. G. (Abraham Getachew), Kengne, A. P. (Andre Pascal), Ketema, D. B. (Daniel Bekele), Khader, Y. S. (Yousef Saleh), Khafaie, M. A. (Morteza Abdullatif), Khalid, N. (Nauman), Khalilov, R. (Rovshan), Khan, E. A. (Ejaz Ahmad), Khan, J. (Junaid), Khan, M. N. (Md Nuruzzaman), Khan, M. S. (Muhammad Shahzeb), Khatab, K. (Khaled), Khater, A. M. (Amir M.), Khater, M. M. (Mona M.), Khayamzadeh, M. (Maryam), Khazaei, M. (Mohammad), Khazaei, S. (Salman), Khosravi, M. H. (Mohammad Hossein), Khubchandani, J. (Jagdish), Kiadaliri, A. (Ali), Kim, Y. J. (Yun Jin), Kimokoti, R. W. (Ruth W.), Kisa, A. (Adnan), Kisa, S. (Sezer), Kissoon, N. (Niranjan), Shivakumar, K. M. (K. M.), Kochhar, S. (Sonali), Kolola, T. (Tufa), Komaki, H. (Hamidreza), Kosen, S. (Soewarta), Koul, P. A. (Parvaiz A.), Koyanagi, A. (Ai), Kraemer, M. U. (Moritz U. G.), Krishan, K. (Kewal), Kugbey, N. (Nuworza), Kumar, G. A. (G. Anil), Kumar, M. (Manasi), Kumar, P. (Pushpendra), Kusuma, V. K. (Vivek Kumar Dian), La Vecchia, C. (Carlo), Lacey, B. (Ben), Lad, S. D. (Sheetal D.), Lal, D. K. (Dharmesh Kumar), Lam, F. (Felix), Lami, F. H. (Faris Hasan), Lamichhane, P. (Prabhat), Lansingh, V. C. (Van Charles), Lasrado, S. (Savita), Laxmaiah, A. (Avula), Lee, P. H. (Paul H.), LeGrand, K. E. (Kate E.), Leili, M. (Mostafa), Lenjebo, T. L. (Tsegaye Lolaso), Leshargie, C. T. (Cheru Tesema), Levine, A. J. (Aubrey J.), Li, S. (Shanshan), Linn, S. (Shai), Liu, S. (Shiwei), Liu, S. (Simin), Lodha, R. (Rakesh), Longbottom, J. (Joshua), Lopez, J. C. (Jaifred Christian F.), Abd El Razek, H. M. (Hassan Magdy), Abd El Razek, M. M. (Muhammed Magdy), Prasad, D. R. (D. R. Mahadeshwara), Mahasha, P. W. (Phetole Walter), Mahotra, N. B. (Narayan B.), Majeed, A. (Azeem), Malekzadeh, R. (Reza), Malta, D. C. (Deborah Carvalho), Mamun, A. A. (Abdullah A.), Manafi, N. (Navid), Manda, A. L. (Ana Laura), Manohar, N. D. (Narendar Dawani Dawanu), Mansournia, M. A. (Mohammad Ali), Mapoma, C. C. (Chabila Christopher), Maravilla, J. C. (Joemer C.), Martinez, G. (Gabriel), Martini, S. (Santi), Martins-Melo, F. R. (Francisco Rogerlandio), Masaka, A. (Anthony), Massenburg, B. B. (Benjamin Ballard), Mathur, M. R. (Manu Raj), Mayala, B. K. (Benjamin K.), Mazidi, M. (Mohsen), McAlinden, C. (Colm), Meharie, B. G. (Birhanu Geta), Mehndiratta, M. M. (Man Mohan), Mehta, K. M. (Kala M.), Mekonnen, T. C. (Tefera Chane), Meles, G. G. (Gebrekiros Gebremichael), Memiah, P. T. (Peter T. N.), Memish, Z. A. (Ziad A.), Mendoza, W. (Walter), Menezes, R. G. (Ritesh G.), Mereta, S. T. (Seid Tiku), Meretoja, T. J. (Tuomo J.), Mestrovic, T. (Tomislav), Miazgowski, B. (Bartosz), Mihretie, K. M. (Kebadnew Mulatu), Miller, T. R. (Ted R.), Mini, G. K. (G. K.), Mirrakhimov, E. M. (Erkin M.), Moazen, B. (Babak), Mohajer, B. (Bahram), Mohamadi-Bolbanabad, A. (Amjad), Mohammad, D. K. (Dara K.), Mohammad, K. A. (Karzan Abdulmuhsin), Mohammad, Y. (Yousef), Mezerji, N. M. (Naser Mohammad Gholi), Mohammadibakhsh, R. (Roghayeh), Mohammadifard, N. (Noushin), Mohammed, J. A. (Jemal Abdu), Mohammed, S. (Shafiu), Mohebi, F. (Farnam), Mokdad, A. H. (Ali H.), Molokhia, M. (Mariam), Monasta, L. (Lorenzo), Moodley, Y. (Yoshan), Moore, C. E. (Catrin E.), Moradi, G. (Ghobad), Moradi, M. (Masoud), Moradi-Joo, M. (Mohammad), Moradi-Lakeh, M. (Maziar), Moraga, P. (Paula), Morales, L. (Linda), Velasquez, I. M. (Ilais Moreno), Mosapour, A. (Abbas), Mouodi, S. (Simin), Mousavi, S. M. (Seyyed Meysam), Mozaffor, M. (Miliva), Muchie, K. F. (Kindie Fentahun), Mulaw, G. F. (Getahun Fentaw), Munro, S. B. (Sandra B.), Muriithi, M. K. (Moses K.), Murray, C. J. (Christoper J. L.), Murthy, G. V. (G. V. S.), Musa, K. I. (Kamarul Imran), Mustafa, G. (Ghulam), Muthupandian, S. (Saravanan), Nabhan, A. F. (Ashraf F.), Naderi, M. (Mehdi), Nagarajan, A. J. (Ahamarshan Jayaraman), Naidoo, K. S. (Kovin S.), Naik, G. (Gurudatta), Najafi, F. (Farid), Nangia, V. (Vinay), Nansseu, J. R. (Jobert Richie), Nascimento, B. R. (Bruno Ramos), Nazari, J. (Javad), Ndwandwe, D. E. (Duduzile Edith), Negoi, I. (Ionut), Netsere, H. B. (Henok Biresaw), Ngunjiri, J. W. (Josephine W.), Nguyen, C. T. (Cuong Tat), Nguyen, H. L. (Huong Lan Thi), Nguyen, T. H. (Trang Huyen), Nigatu, D. (Dabere), Nigatu, S. G. (Solomon Gedlu), Ningrum, D. N. (Dina Nur Anggraini), Nnaji, C. A. (Chukwudi A.), Nojomi, M. (Marzieh), Nong, V. M. (Vuong Minh), Norheim, O. F. (Ole F.), Noubiap, J. J. (Jean Jacques), Motlagh, S. N. (Soraya Nouraei), Oancea, B. (Bogdan), Ogah, O. S. (Okechukwu Samuel), Ogbo, F. A. (Felix Akpojene), Oh, I.-H. (In-Hwan), Olagunju, A. T. (Andrew T.), Olagunju, T. O. (Tinuke O.), Olusanya, B. O. (Bolajoko Olubukunola), Olusanya, J. O. (Jacob Olusegun), Onwujekwe, O. E. (Obinna E.), Oren, E. (Eyal), Ortega-Altamirano, D. V. (Doris V.), Osarenotor, O. (Osayomwanbo), Osei, F. B. (Frank B.), Owolabi, M. O. (Mayowa O.), Mahesh, P. A. (P. A.), Padubidri, J. R. (Jagadish Rao), Pakhale, S. (Smita), Patel, S. K. (Sangram Kishor), Paternina-Caicedo, A. J. (Angel J.), Pathak, A. (Ashish), Patton, G. C. (George C.), Paudel, D. (Deepak), Paulos, K. (Kebreab), Pepito, V. C. (Veincent Christian Filipino), Pereira, A. (Alexandre), Perico, N. (Norberto), Pervaiz, A. (Aslam), Pescarini, J. M. (Julia Moreira), Piroozi, B. (Bakhtiar), Pirsaheb, M. (Meghdad), Postma, M. J. (Maarten J.), Pourjafar, H. (Hadi), Pourmalek, F. (Farshad), Pourshams, A. (Akram), Poustchi, H. (Hossein), Prada, S. I. (Sergio I.), Prasad, N. (Narayan), Preotescu, L. (Liliana), Quintana, H. (Hedley), Rabiee, N. (Navid), Radfar, A. (Amir), Rafiei, A. (Alireza), Rahim, F. (Fakher), Rahimi-Movaghar, A. (Afarin), Rahimi-Movaghar, V. (Vafa), Rahman, M. H. (Mohammad Hifz Ur), Rahman, M. A. (Muhammad Aziz), Rahman, S. (Shafiur), Rajati, F. (Fatemeh), Rana, S. M. (Saleem Muhammad), Ranabhat, C. L. (Chhabi Lal), Rasella, D. (Davide), Rawaf, D. L. (David Laith), Rawaf, S. (Salman), Rawal, L. (Lal), Rawasia, W. F. (Wasiq Faraz), Renjith, V. (Vishnu), Renzaho, A. M. (Andre M. N.), Resnikoff, S. (Serge), Reta, M. A. (Melese Abate), Rezaei, N. (Negar), Rezai, M. S. (Mohammad Sadegh), Riahi, S. M. (Seyed Mohammad), Ribeiro, A. I. (Ana Isabel), Rickard, J. (Jennifer), Rios-Blancas, M. (Maria), Roever, L. (Leonardo), Ronfani, L. (Luca), Roro, E. M. (Elias Merdassa), Ross, J. M. (Jennifer M.), Rubagotti, E. (Enrico), Rubino, S. (Salvatore), Saad, A. M. (Anas M.), Sabde, Y. D. (Yogesh Damodar), Sabour, S. (Siamak), Sadeghi, E. (Ehsan), Safari, Y. (Yahya), Safari-Faramani, R. (Roya), Sagar, R. (Rajesh), Sahebkar, A. (Amirhossein), Sahraian, M. A. (Mohammad Ali), Sajadi, S. M. (S. Mohammad), Salahshoor, M. R. (Mohammad Reza), Salam, N. (Nasir), Salamati, P. (Payman), Salem, H. (Hosni), Salem, M. R. (Marwa Rashad), Salimi, Y. (Yahya), Salimzadeh, H. (Hamideh), Samy, A. M. (Abdallah M.), Sanabria, J. (Juan), Santric-Milicevic, M. M. (Milena M.), Jose, B. P. (Bruno Piassi Sao), Saraswathy, S. Y. (Sivan Yegnanarayana Iyer), Sarkar, K. (Kaushik), Sarker, A. R. (Abdur Razzaque), Sarrafzadegan, N. (Nizal), Sartorius, B. (Benn), Sathian, B. (Brijesh), Sathish, T. (Thirunavukkarasu), Sawhney, M. (Monika), Saxena, S. (Sonia), Schwebel, D. C. (David C.), Senbeta, A. M. (Anbissa Muleta), Senthilkumaran, S. (Subramanian), Sepanlou, S. G. (Sadaf G.), Servan-Mori, E. (Edson), Shabaninejad, H. (Hosein), Shafieesabet, A. (Azadeh), Shaikh, M. A. (Masood Ali), Shalash, A. S. (Ali S.), Shallo, S. A. (Seifadin Ahmed), Shams-Beyranvand, M. (Mehran), Shamsi, M. (MohammadBagher), Shamsizadeh, M. (Morteza), Shannawaz, M. (Mohammed), Sharafi, K. (Kiomars), Sharifi, H. (Hamid), Shehata, H. S. (Hatem Samir), Sheikh, A. (Aziz), Shetty, B. S. (B. Suresh Kumar), Shibuya, K. (Kenji), Shiferaw, W. S. (Wondimeneh Shibabaw), Shifti, D. M. (Desalegn Markos), Shigematsu, M. (Mika), Il Shin, J. (Jae), Shiri, R. (Rahman), Shirkoohi, R. (Reza), Siabani, S. (Soraya), Siddiqi, T. J. (Tariq Jamal), Silva, D. A. (Diego Augusto Santos), Singh, A. (Ambrish), Singh, J. A. (Jasvinder A.), Singh, N. P. (Narinder Pal), Singh, V. (Virendra), Sisay, M. M. (Malede Mequanent), Skiadaresi, E. (Eirini), Sobhiyeh, M. R. (Mohammad Reza), Sokhan, A. (Anton), Soltani, S. (Shahin), Somayaji, R. (Ranjani), Soofi, M. (Moslem), Sorrie, M. B. (Muluken Bekele), Soyiri, I. N. (Ireneous N.), Sreeramareddy, C. T. (Chandrashekhar T.), Sudaryanto, A. (Agus), Sufiyan, M. B. (Mu'awiyyah Babale), Suleria, H. A. (Hafiz Ansar Rasul), Sultana, M. (Marufa), Sunguya, B. F. (Bruno Fokas), Sykes, B. L. (Bryan L.), Tabares-Seisdedos, R. (Rafael), Tabuchi, T. (Takahiro), Tadesse, D. B. (Degena Bahrey), Tarigan, I. U. (Ingan Ukur), Tasew, A. A. (Aberash Abay), Tefera, Y. M. (Yonatal Mesfin), Tekle, M. G. (Merhawi Gebremedhin), Temsah, M.-H. (Mohamad-Hani), Tesfay, B. E. (Berhe Etsay), Tesfay, F. H. (Fisaha Haile), Tessema, B. (Belay), Tessema, Z. T. (Zemenu Tadesse), Thankappan, K. R. (Kavumpurathu Raman), Thomas, N. (Nihal), Toma, A. (Alemayehu), Topor-Madry, R. (Roman), Tovani-Palone, M. R. (Marcos Roberto), Traini, E. (Eugenio), Tran, B. X. (Bach Xuan), Tran, K. B. (Khanh Bao), Ullah, I. (Irfan), Unnikrishnan, B. (Bhaskaran), Usman, M. S. (Muhammad Shariq), Uzochukwu, B. S. (Benjamin S. Chudi), Valdez, P. R. (Pascual R.), Varughese, S. (Santosh), Violante, F. S. (Francesco S.), Vollmer, S. (Sebastian), Hawariat, F. G. (Feleke Gebremeskel W.), Waheed, Y. (Yasir), Wallin, M. T. 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(Nejimu Biza), Zerfu, T. A. (Taddese Alemu), Zhang, Y. (Yunquan), Zhao, X. G. (Xiu-Ju George), Ziapour, A. (Arash), Zodpey, S. (Sanjay), Zuniga, Y. M. (Yves Miel H.), Hay, S. I. (Simon I.), Reiner, R. C. (Robert C., Jr.), Wiens, K. E. (Kirsten E.), Lindstedt, P. A. (Paulina A.), Blacker, B. F. (Brigette F.), Johnson, K. B. (Kimberly B.), Baumann, M. M. (Mathew M.), Schaeffer, L. E. (Lauren E.), Abbastabar, H. (Hedayat), Abd-Allah, F. (Foad), Abdelalim, A. (Ahmed), Abdollahpour, I. (Ibrahim), Abegaz, K. H. (Kedir Hussein), Abejie, A. N. (Ayenew Negesse), Abreu, L. G. (Lucas Guimaraes), Abrigo, M. R. (Michael R. M.), Abualhasan, A. (Ahmed), Accrombessi, M. M. (Manfred Mario Kokou), Acharya, D. (Dilaram), Adabi, M. (Maryam), Adamu, A. A. (Abdu A.), Adebayo, O. M. (Oladimeji M.), Adedoyin, R. A. (Rufus Adesoji), Adekanmbi, V. (Victor), Adetokunboh, O. O. (Olatunji O.), Adhena, B. M. (Beyene Meressa), Afarideh, M. (Mohsen), Ahmad, S. (Sohail), Ahmadi, K. (Keivan), Ahmed, A. E. (Anwar E.), Ahmed, M. B. (Muktar Beshir), Ahmed, R. (Rushdia), Akalu, T. Y. (Temesgen Yihunie), Alahdab, F. (Fares), Al-Aly, Z. (Ziyad), Alam, N. (Noore), Alam, S. (Samiah), Alamene, G. M. (Genet Melak), Alanzi, T. M. (Turki M.), Alcalde-Rabanal, J. E. (Jacqueline Elizabeth), Ali, B. A. (Beriwan Abdulqadir), Alijanzadeh, M. (Mehran), Alipour, V. (Vahid), Aljunid, S. M. (Syed Mohamed), Almasi, A. (Ali), Almasi-Hashiani, A. (Amir), Al-Mekhlafi, H. M. (Hesham M.), Altirkawi, K. A. (Khalid A.), Alvis-Guzman, N. (Nelson), Alvis-Zakzuk, N. J. (Nelson J.), Amini, S. (Saeed), Amit, A. M. (Arianna Maever L.), Andrei, C. L. (Catalina Liliana), Anjomshoa, M. (Mina), Anoushiravani, A. (Amir), Ansari, F. (Fereshteh), Antonio, C. A. (Carl Abelardo T.), Antony, B. (Benny), Antriyandarti, E. (Ernoiz), Arabloo, J. (Jalal), Aref, H. M. (Hany Mohamed Amin), Aremu, O. (Olatunde), Armoon, B. (Bahram), Arora, A. (Amit), Aryal, K. K. (Krishna K.), Arzani, A. (Afsaneh), Asadi-Aliabadi, M. (Mehran), Atalay, H. T. (Hagos Tasew), Athari, S. S. (Seyyed Shamsadin), Athari, S. M. (Seyyede Masoume), Atre, S. R. (Sachin R.), Ausloos, M. (Marcel), Awoke, N. (Nefsu), Quintanilla, B. P. (Beatriz Paulina Ayala), Ayano, G. (Getinet), Ayanore, M. A. (Martin Amogre), Aynalem, Y. A. (Yared Asmare), Azari, S. (Samad), Azzopardi, P. S. (Peter S.), Babaee, E. (Ebrahim), Babalola, T. K. (Tesleem Kayode), Badawi, A. (Alaa), Bairwa, M. (Mohan), Bakkannavar, S. M. (Shankar M.), Balakrishnan, S. (Senthilkumar), Bali, A. G. (Ayele Geleto), Banach, M. (Maciej), Banoub, J. A. (Joseph Adel Mattar), Barac, A. (Aleksandra), Barnighausen, T. W. (Till Winfried), Basaleem, H. (Huda), Basu, S. (Sanjay), Bay, V. D. (Vo Dinh), Bayati, M. (Mohsen), Baye, E. (Estifanos), Bedi, N. (Neeraj), Beheshti, M. (Mahya), Behzadifar, M. (Masoud), Behzadifar, M. (Meysam), Bekele, B. B. (Bayu Begashaw), Belayneh, Y. M. (Yaschilal Muche), Bell, M. L. (Michelle L.), Bennett, D. A. (Derrick A.), Berbada, D. A. (Dessalegn Ajema), Bernstein, R. S. (Robert S.), Bhat, A. G. (Anusha Ganapati), Bhattacharyya, K. (Krittika), Bhattarai, S. (Suraj), Bhaumik, S. (Soumyadeep), Bhutta, Z. A. (Zulfiqar A.), Bijani, A. (Ali), Bikbov, B. (Boris), Birihane, B. M. (Binyam Minuye), Biswas, R. K. (Raaj Kishore), Bohlouli, S. (Somayeh), Bojia, H. A. (Hunduma Amensisa), Boufous, S. (Soufiane), Brady, O. J. (Oliver J.), Bragazzi, N. L. (Nicola Luigi), Briko, A. N. (Andrey Nikolaevich), Briko, N. I. (Nikolay Ivanovich), Britton, G. B. (Gabrielle B.), Nagaraja, S. B. (Sharath Burugina), Busse, R. (Reinhard), Butt, Z. A. (Zahid A.), Camera, L. A. (Luis Alberto), Campos-Nonato, I. R. (Ismael R.), Cano, J. (Jorge), Car, J. (Josip), Cardenas, R. (Rosario), Carvalho, F. (Felix), Castaneda-Orjuela, C. A. (Carlos A.), Castro, F. (Franz), Chanie, W. F. (Wagaye Fentahun), Chatterjee, P. (Pranab), Chattu, V. K. (Vijay Kumar), Chichiabellu, T. Y. (Tesfaye Yitna), Chin, K. L. (Ken Lee), Christopher, D. J. (Devasahayam J.), Chu, D.-T. (Dinh-Toi), Cormier, N. M. (Natalie Maria), Costa, V. M. (Vera Marisa), Culquichicon, C. (Carlos), Daba, M. S. (Matiwos Soboka), Damiani, G. (Giovanni), Dandona, L. (Lalit), Dandona, R. (Rakhi), Dang, A. K. (Anh Kim), Darwesh, A. M. (Aso Mohammad), Darwish, A. H. (Amira Hamed), Daryani, A. (Ahmad), Das, J. K. (Jai K.), Das Gupta, R. (Rajat), Dash, A. P. (Aditya Prasad), Davey, G. (Gail), Davila-Cervantes, C. A. (Claudio Alberto), Davis, A. C. (Adrian C.), Davitoiu, D. V. (Dragos Virgil), De la Hoz, F. P. (Fernando Pio), Demis, A. B. (Asmamaw Bizuneh), Demissie, D. B. (Dereje Bayissa), Demissie, G. D. (Getu Debalkie), Demoz, G. T. (Gebre Teklemariam), Denova-Gutierrez, E. (Edgar), Deribe, K. (Kebede), Desalew, A. (Assefa), Deshpande, A. (Aniruddha), Dharmaratne, S. D. (Samath Dhamminda), Dhillon, P. (Preeti), Dhimal, M. (Meghnath), Dhungana, G. P. (Govinda Prasad), Diaz, D. (Daniel), Dipeolu, I. O. (Isaac Oluwafemi), Djalalinia, S. (Shirin), Doyle, K. E. (Kerrie E.), Dubljanin, E. (Eleonora), Duko, B. (Bereket), Duraes, A. R. (Andre Rodrigues), Kalan, M. E. (Mohammad Ebrahimi), Edinur, H. A. (Hisham Atan), Effiong, A. (Andem), Eftekhari, A. (Aziz), El Nahas, N. (Nevine), El Sayed, I. (Iman), Zaki, M. E. (Maysaa El Sayed), El Tantawi, M. (Maha), Elema, T. B. (Teshome Bekele), Elhabashy, H. R. (Hala Rashad), El-Jaafary, S. I. (Shaimaa I.), Elkout, H. (Hajer), Elsharkawy, A. (Aisha), Elyazar, I. R. (Iqbal R. F.), Endalamaw, A. (Aklilu), Endalew, D. A. (Daniel Adane), Eskandarieh, S. (Sharareh), Esteghamati, A. (Alireza), Esteghamati, S. (Sadaf), Etemadi, A. (Arash), Ezekannagha, O. (Oluchi), Fareed, M. (Mohammad), Faridnia, R. (Roghiyeh), Farzadfar, F. (Farshad), Fazlzadeh, M. (Mehdi), Feigin, V. L. (Valery L.), Fereshtehnejad, S.-M. (Seyed-Mohammad), Fernandes, E. (Eduarda), Filip, I. (Irina), Fischer, F. (Florian), Foigt, N. A. (Nataliya A.), Folayan, M. O. (Morenike Oluwatoyin), Foroutan, M. (Masoud), Franklin, R. C. (Richard Charles), Fukumoto, T. (Takeshi), Gad, M. M. (Mohamed M.), Gayesa, R. T. (Reta Tsegaye), Gebre, T. (Teshome), Gebremedhin, K. B. (Ketema Bizuwork), Gebremeskel, G. G. (Gebreamlak Gebremedhn), Gesesew, H. A. (Hailay Abrha), Gezae, K. E. (Kebede Embaye), Ghadiri, K. (Keyghobad), Ghashghaee, A. (Ahmad), Ghimire, P. R. (Pramesh Raj), Gill, P. S. (Paramjit Singh), Gill, T. K. (Tiffany K.), Ginindza, T. G. (Themba G.), Gomes, N. G. (Nelson G. M.), Gopalani, S. V. (Sameer Vali), Goulart, A. C. (Alessandra C.), Goulart, B. N. (Barbara Niegia Garcia), Grada, A. (Ayman), Gubari, M. I. (Mohammed Ibrahim Mohialdeen), Gugnani, H. C. (Harish Chander), Guido, D. (Davide), Guimaraes, R. A. (Rafael Alves), Guo, Y. (Yuming), Gupta, R. (Rajeev), Hafezi-Nejad, N. (Nima), Haile, D. H. (Dessalegn H.), Hailu, G. B. (Gessessew Bugssa), Haj-Mirzaian, A. (Arvin), Haj-Mirzaian, A. (Arya), Hamadeh, R. R. (Randah R.), Hamidi, S. (Samer), Handiso, D. W. (Demelash Woldeyohannes), Haririan, H. (Hamidreza), Hariyani, N. (Ninuk), Hasaballah, A. I. (Ahmed I.), Hasan, M. M. (Md Mehedi), Hasanpoor, E. (Edris), Hasanzadeh, A. (Amir), Hassankhani, H. (Hadi), Hassen, H. Y. (Hamid Yimam), Hegazy, M. I. (Mohamed I.), Heibati, B. (Behzad), Heidari, B. (Behnam), Hendrie, D. (Delia), Henry, N. J. (Nathaniel J.), Herteliu, C. (Claudiu), Heydarpour, F. (Fatemeh), de Hidru, H. D. (Hagos Degefa), Hird, T. R. (Thomas R.), Hoang, C. L. (Chi Linh), Rad, E. H. (Enayatollah Homaie), Hoogar, P. (Praveen), Hoseini, M. (Mohammad), Hossain, N. (Naznin), Hosseini, M. (Mostafa), Hosseinzadeh, M. (Mehdi), Househ, M. (Mowafa), Hsairi, M. (Mohamed), Hu, G. (Guoqing), Hussen, M. M. (Mohammedaman Mama), Ibitoye, S. E. (Segun Emmanuel), Igumbor, E. U. (Ehimario U.), Ilesanmi, O. S. (Olayinka Stephen), Ilic, M. D. (Milena D.), Imani-Nasab, M. H. (Mohammad Hasan), Iqbal, U. (Usman), Irvani, S. S. (Seyed Sina Naghibi), Islam, S. M. (Sheikh Mohammed Shariful), Iwu, C. J. (Chinwe Juliana), Izadi, N. (Neda), Jaca, A. (Anelisa), Jahanmehr, N. (Nader), Jakovljevic, M. (Mihajlo), Jalali, A. (Amir), Jayatilleke, A. U. (Achala Upendra), Jha, R. P. (Ravi Prakash), Jha, V. (Vivekanand), Ji, J. S. (John S.), Jonas, J. B. (Jost B.), Jozwiak, J. J. (Jacek Jerzy), Kabir, A. (Ali), Kabir, Z. (Zubair), Kahsay, A. (Amaha), Kalani, H. (Hamed), Kanchan, T. (Tanuj), Matin, B. K. (Behzad Karami), Karch, A. (Andre), Karim, M. A. (Mohd Anisul), Karki, H. K. (Hamidreza Karimi-Sari Surendra), Kasaeian, A. (Amir), Kasahun, G. G. (Gebremicheal Gebreslassie), Kasahun, Y. C. (Yawukal Chane), Kasaye, H. K. (Habtamu Kebebe), Kassa, G. G. (Gebrehiwot G.), Kassa, G. M. (Getachew Mullu), Kayode, G. A. (Gbenga A.), Karyani, A. K. (Ali Kazemi), Kebede, M. M. (Mihiretu M.), Keiyoro, P. N. (Peter Njenga), Kelbore, A. G. (Abraham Getachew), Kengne, A. P. (Andre Pascal), Ketema, D. B. (Daniel Bekele), Khader, Y. S. (Yousef Saleh), Khafaie, M. A. (Morteza Abdullatif), Khalid, N. (Nauman), Khalilov, R. (Rovshan), Khan, E. A. (Ejaz Ahmad), Khan, J. (Junaid), Khan, M. N. (Md Nuruzzaman), Khan, M. S. (Muhammad Shahzeb), Khatab, K. (Khaled), Khater, A. M. (Amir M.), Khater, M. M. (Mona M.), Khayamzadeh, M. (Maryam), Khazaei, M. (Mohammad), Khazaei, S. (Salman), Khosravi, M. H. (Mohammad Hossein), Khubchandani, J. (Jagdish), Kiadaliri, A. (Ali), Kim, Y. J. (Yun Jin), Kimokoti, R. W. (Ruth W.), Kisa, A. (Adnan), Kisa, S. (Sezer), Kissoon, N. (Niranjan), Shivakumar, K. M. (K. M.), Kochhar, S. (Sonali), Kolola, T. (Tufa), Komaki, H. (Hamidreza), Kosen, S. (Soewarta), Koul, P. A. (Parvaiz A.), Koyanagi, A. (Ai), Kraemer, M. U. (Moritz U. G.), Krishan, K. (Kewal), Kugbey, N. (Nuworza), Kumar, G. A. (G. Anil), Kumar, M. (Manasi), Kumar, P. (Pushpendra), Kusuma, V. K. (Vivek Kumar Dian), La Vecchia, C. (Carlo), Lacey, B. (Ben), Lad, S. D. (Sheetal D.), Lal, D. K. (Dharmesh Kumar), Lam, F. (Felix), Lami, F. H. (Faris Hasan), Lamichhane, P. (Prabhat), Lansingh, V. C. (Van Charles), Lasrado, S. (Savita), Laxmaiah, A. (Avula), Lee, P. H. (Paul H.), LeGrand, K. E. (Kate E.), Leili, M. (Mostafa), Lenjebo, T. L. (Tsegaye Lolaso), Leshargie, C. T. (Cheru Tesema), Levine, A. J. (Aubrey J.), Li, S. (Shanshan), Linn, S. (Shai), Liu, S. (Shiwei), Liu, S. (Simin), Lodha, R. (Rakesh), Longbottom, J. (Joshua), Lopez, J. C. (Jaifred Christian F.), Abd El Razek, H. M. (Hassan Magdy), Abd El Razek, M. M. (Muhammed Magdy), Prasad, D. R. (D. R. Mahadeshwara), Mahasha, P. W. (Phetole Walter), Mahotra, N. B. (Narayan B.), Majeed, A. (Azeem), Malekzadeh, R. (Reza), Malta, D. C. (Deborah Carvalho), Mamun, A. A. (Abdullah A.), Manafi, N. (Navid), Manda, A. L. (Ana Laura), Manohar, N. D. (Narendar Dawani Dawanu), Mansournia, M. A. (Mohammad Ali), Mapoma, C. C. (Chabila Christopher), Maravilla, J. C. (Joemer C.), Martinez, G. (Gabriel), Martini, S. (Santi), Martins-Melo, F. R. (Francisco Rogerlandio), Masaka, A. (Anthony), Massenburg, B. B. (Benjamin Ballard), Mathur, M. R. (Manu Raj), Mayala, B. K. (Benjamin K.), Mazidi, M. (Mohsen), McAlinden, C. (Colm), Meharie, B. G. (Birhanu Geta), Mehndiratta, M. M. (Man Mohan), Mehta, K. M. (Kala M.), Mekonnen, T. C. (Tefera Chane), Meles, G. G. (Gebrekiros Gebremichael), Memiah, P. T. (Peter T. N.), Memish, Z. A. (Ziad A.), Mendoza, W. (Walter), Menezes, R. G. (Ritesh G.), Mereta, S. T. (Seid Tiku), Meretoja, T. J. (Tuomo J.), Mestrovic, T. (Tomislav), Miazgowski, B. (Bartosz), Mihretie, K. M. (Kebadnew Mulatu), Miller, T. R. (Ted R.), Mini, G. K. (G. K.), Mirrakhimov, E. M. (Erkin M.), Moazen, B. (Babak), Mohajer, B. (Bahram), Mohamadi-Bolbanabad, A. (Amjad), Mohammad, D. K. (Dara K.), Mohammad, K. A. (Karzan Abdulmuhsin), Mohammad, Y. (Yousef), Mezerji, N. M. (Naser Mohammad Gholi), Mohammadibakhsh, R. (Roghayeh), Mohammadifard, N. (Noushin), Mohammed, J. A. (Jemal Abdu), Mohammed, S. (Shafiu), Mohebi, F. (Farnam), Mokdad, A. H. (Ali H.), Molokhia, M. (Mariam), Monasta, L. (Lorenzo), Moodley, Y. (Yoshan), Moore, C. E. (Catrin E.), Moradi, G. (Ghobad), Moradi, M. (Masoud), Moradi-Joo, M. (Mohammad), Moradi-Lakeh, M. (Maziar), Moraga, P. (Paula), Morales, L. (Linda), Velasquez, I. M. (Ilais Moreno), Mosapour, A. (Abbas), Mouodi, S. (Simin), Mousavi, S. M. (Seyyed Meysam), Mozaffor, M. (Miliva), Muchie, K. F. (Kindie Fentahun), Mulaw, G. F. (Getahun Fentaw), Munro, S. B. (Sandra B.), Muriithi, M. K. (Moses K.), Murray, C. J. (Christoper J. L.), Murthy, G. V. (G. V. S.), Musa, K. I. (Kamarul Imran), Mustafa, G. (Ghulam), Muthupandian, S. (Saravanan), Nabhan, A. F. (Ashraf F.), Naderi, M. (Mehdi), Nagarajan, A. J. (Ahamarshan Jayaraman), Naidoo, K. S. (Kovin S.), Naik, G. (Gurudatta), Najafi, F. (Farid), Nangia, V. (Vinay), Nansseu, J. R. (Jobert Richie), Nascimento, B. R. (Bruno Ramos), Nazari, J. (Javad), Ndwandwe, D. E. (Duduzile Edith), Negoi, I. (Ionut), Netsere, H. B. (Henok Biresaw), Ngunjiri, J. W. (Josephine W.), Nguyen, C. T. (Cuong Tat), Nguyen, H. L. (Huong Lan Thi), Nguyen, T. H. (Trang Huyen), Nigatu, D. (Dabere), Nigatu, S. G. (Solomon Gedlu), Ningrum, D. N. (Dina Nur Anggraini), Nnaji, C. A. (Chukwudi A.), Nojomi, M. (Marzieh), Nong, V. M. (Vuong Minh), Norheim, O. F. (Ole F.), Noubiap, J. J. (Jean Jacques), Motlagh, S. N. (Soraya Nouraei), Oancea, B. (Bogdan), Ogah, O. S. (Okechukwu Samuel), Ogbo, F. A. (Felix Akpojene), Oh, I.-H. (In-Hwan), Olagunju, A. T. (Andrew T.), Olagunju, T. O. (Tinuke O.), Olusanya, B. O. (Bolajoko Olubukunola), Olusanya, J. O. (Jacob Olusegun), Onwujekwe, O. E. (Obinna E.), Oren, E. (Eyal), Ortega-Altamirano, D. V. (Doris V.), Osarenotor, O. (Osayomwanbo), Osei, F. B. (Frank B.), Owolabi, M. O. (Mayowa O.), Mahesh, P. A. (P. A.), Padubidri, J. R. (Jagadish Rao), Pakhale, S. (Smita), Patel, S. K. (Sangram Kishor), Paternina-Caicedo, A. J. (Angel J.), Pathak, A. (Ashish), Patton, G. C. (George C.), Paudel, D. (Deepak), Paulos, K. (Kebreab), Pepito, V. C. (Veincent Christian Filipino), Pereira, A. (Alexandre), Perico, N. (Norberto), Pervaiz, A. (Aslam), Pescarini, J. M. (Julia Moreira), Piroozi, B. (Bakhtiar), Pirsaheb, M. (Meghdad), Postma, M. J. (Maarten J.), Pourjafar, H. (Hadi), Pourmalek, F. (Farshad), Pourshams, A. (Akram), Poustchi, H. (Hossein), Prada, S. I. (Sergio I.), Prasad, N. (Narayan), Preotescu, L. (Liliana), Quintana, H. (Hedley), Rabiee, N. (Navid), Radfar, A. (Amir), Rafiei, A. (Alireza), Rahim, F. (Fakher), Rahimi-Movaghar, A. (Afarin), Rahimi-Movaghar, V. (Vafa), Rahman, M. H. (Mohammad Hifz Ur), Rahman, M. A. (Muhammad Aziz), Rahman, S. (Shafiur), Rajati, F. (Fatemeh), Rana, S. M. (Saleem Muhammad), Ranabhat, C. L. (Chhabi Lal), Rasella, D. (Davide), Rawaf, D. L. (David Laith), Rawaf, S. (Salman), Rawal, L. (Lal), Rawasia, W. F. (Wasiq Faraz), Renjith, V. (Vishnu), Renzaho, A. M. (Andre M. N.), Resnikoff, S. (Serge), Reta, M. A. (Melese Abate), Rezaei, N. (Negar), Rezai, M. S. (Mohammad Sadegh), Riahi, S. M. (Seyed Mohammad), Ribeiro, A. I. (Ana Isabel), Rickard, J. (Jennifer), Rios-Blancas, M. (Maria), Roever, L. (Leonardo), Ronfani, L. (Luca), Roro, E. M. (Elias Merdassa), Ross, J. M. (Jennifer M.), Rubagotti, E. (Enrico), Rubino, S. (Salvatore), Saad, A. M. (Anas M.), Sabde, Y. D. (Yogesh Damodar), Sabour, S. (Siamak), Sadeghi, E. (Ehsan), Safari, Y. (Yahya), Safari-Faramani, R. (Roya), Sagar, R. (Rajesh), Sahebkar, A. (Amirhossein), Sahraian, M. A. (Mohammad Ali), Sajadi, S. M. (S. Mohammad), Salahshoor, M. R. (Mohammad Reza), Salam, N. (Nasir), Salamati, P. (Payman), Salem, H. (Hosni), Salem, M. R. (Marwa Rashad), Salimi, Y. (Yahya), Salimzadeh, H. (Hamideh), Samy, A. M. (Abdallah M.), Sanabria, J. (Juan), Santric-Milicevic, M. M. (Milena M.), Jose, B. P. (Bruno Piassi Sao), Saraswathy, S. Y. (Sivan Yegnanarayana Iyer), Sarkar, K. (Kaushik), Sarker, A. R. (Abdur Razzaque), Sarrafzadegan, N. (Nizal), Sartorius, B. (Benn), Sathian, B. (Brijesh), Sathish, T. (Thirunavukkarasu), Sawhney, M. (Monika), Saxena, S. (Sonia), Schwebel, D. C. (David C.), Senbeta, A. M. (Anbissa Muleta), Senthilkumaran, S. (Subramanian), Sepanlou, S. G. (Sadaf G.), Servan-Mori, E. (Edson), Shabaninejad, H. (Hosein), Shafieesabet, A. (Azadeh), Shaikh, M. A. (Masood Ali), Shalash, A. S. (Ali S.), Shallo, S. A. (Seifadin Ahmed), Shams-Beyranvand, M. (Mehran), Shamsi, M. (MohammadBagher), Shamsizadeh, M. (Morteza), Shannawaz, M. (Mohammed), Sharafi, K. (Kiomars), Sharifi, H. (Hamid), Shehata, H. S. (Hatem Samir), Sheikh, A. (Aziz), Shetty, B. S. (B. Suresh Kumar), Shibuya, K. (Kenji), Shiferaw, W. S. (Wondimeneh Shibabaw), Shifti, D. M. (Desalegn Markos), Shigematsu, M. (Mika), Il Shin, J. (Jae), Shiri, R. (Rahman), Shirkoohi, R. (Reza), Siabani, S. (Soraya), Siddiqi, T. J. (Tariq Jamal), Silva, D. A. (Diego Augusto Santos), Singh, A. (Ambrish), Singh, J. A. (Jasvinder A.), Singh, N. P. (Narinder Pal), Singh, V. (Virendra), Sisay, M. M. (Malede Mequanent), Skiadaresi, E. (Eirini), Sobhiyeh, M. R. (Mohammad Reza), Sokhan, A. (Anton), Soltani, S. (Shahin), Somayaji, R. (Ranjani), Soofi, M. (Moslem), Sorrie, M. B. (Muluken Bekele), Soyiri, I. N. (Ireneous N.), Sreeramareddy, C. T. (Chandrashekhar T.), Sudaryanto, A. (Agus), Sufiyan, M. B. (Mu'awiyyah Babale), Suleria, H. A. (Hafiz Ansar Rasul), Sultana, M. (Marufa), Sunguya, B. F. (Bruno Fokas), Sykes, B. L. (Bryan L.), Tabares-Seisdedos, R. (Rafael), Tabuchi, T. (Takahiro), Tadesse, D. B. (Degena Bahrey), Tarigan, I. U. (Ingan Ukur), Tasew, A. A. (Aberash Abay), Tefera, Y. M. (Yonatal Mesfin), Tekle, M. G. (Merhawi Gebremedhin), Temsah, M.-H. (Mohamad-Hani), Tesfay, B. E. (Berhe Etsay), Tesfay, F. H. (Fisaha Haile), Tessema, B. (Belay), Tessema, Z. T. (Zemenu Tadesse), Thankappan, K. R. (Kavumpurathu Raman), Thomas, N. (Nihal), Toma, A. (Alemayehu), Topor-Madry, R. (Roman), Tovani-Palone, M. R. (Marcos Roberto), Traini, E. (Eugenio), Tran, B. X. (Bach Xuan), Tran, K. B. (Khanh Bao), Ullah, I. (Irfan), Unnikrishnan, B. (Bhaskaran), Usman, M. S. (Muhammad Shariq), Uzochukwu, B. S. (Benjamin S. Chudi), Valdez, P. R. (Pascual R.), Varughese, S. (Santosh), Violante, F. S. (Francesco S.), Vollmer, S. (Sebastian), Hawariat, F. G. (Feleke Gebremeskel W.), Waheed, Y. (Yasir), Wallin, M. T. (Mitchell Taylor), Wang, Y. (Yafeng), Wang, Y.-P. (Yuan-Pang), Weaver, M. (Marcia), Weji, B. G. (Bedilu Girma), Weldesamuel, G. T. (Girmay Teklay), Welgan, C. A. (Catherine A.), Werdecker, A. (Andrea), Westerman, R. (Ronny), Wiangkham, T. (Taweewat), Wiysonge, C. S. (Charles Shey), Wolde, H. F. (Haileab Fekadu), Wondafrash, D. Z. (Dawit Zewdu), Wonde, T. E. (Tewodros Eshete), Worku, G. T. (Getasew Taddesse), Wu, A.-M. (Ai-Min), Xu, G. (Gelin), Yadollahpour, A. (Ali), Jabbari, S. H. (Seyed Hossein Yahyazadeh), Yamada, T. (Tomohide), Yatsuya, H. (Hiroshi), Yeshaneh, A. (Alex), Yilgwan, C. S. (Christopher Sabo), Yilma, M. T. (Mekdes Tigistu), Yip, P. (Paul), Yisma, E. (Engida), Yonemoto, N. (Naohiro), Yoon, S.-J. (Seok-Jun), Younis, M. Z. (Mustafa Z.), Yousefifard, M. (Mahmoud), Yousof, H. S. (Hebat-Allah Salah A.), Yu, C. (Chuanhua), Yusefzadeh, H. (Hasan), Zadey, S. (Siddhesh), Zaidi, Z. (Zoubida), Bin Zaman, S. (Sojib), Zamani, M. (Mohammad), Zandian, H. (Hamed), Zepro, N. B. (Nejimu Biza), Zerfu, T. A. (Taddese Alemu), Zhang, Y. (Yunquan), Zhao, X. G. (Xiu-Ju George), Ziapour, A. (Arash), Zodpey, S. (Sanjay), Zuniga, Y. M. (Yves Miel H.), Hay, S. I. (Simon I.), and Reiner, R. C. (Robert C., Jr.)
Abstract: Background: Oral rehydration solution (ORS) is a form of oral rehydration therapy (ORT) for diarrhoea that has the potential to drastically reduce child mortality; yet, according to UNICEF estimates, less than half of children younger than 5 years with diarrhoea in low-income and middle-income countries (LMICs) received ORS in 2016. A variety of recommended home fluids (RHF) exist as alternative forms of ORT; however, it is unclear whether RHF prevent child mortality. Previous studies have shown considerable variation between countries in ORS and RHF use, but subnational variation is unknown. This study aims to produce high-resolution geospatial estimates of relative and absolute coverage of ORS, RHF, and ORT (use of either ORS or RHF) in LMICs. Methods: We used a Bayesian geostatistical model including 15 spatial covariates and data from 385 household surveys across 94 LMICs to estimate annual proportions of children younger than 5 years of age with diarrhoea who received ORS or RHF (or both) on continuous continent-wide surfaces in 2000–17, and aggregated results to policy-relevant administrative units. Additionally, we analysed geographical inequality in coverage across administrative units and estimated the number of diarrhoeal deaths averted by increased coverage over the study period. Uncertainty in the mean coverage estimates was calculated by taking 250 draws from the posterior joint distribution of the model and creating uncertainty intervals (UIs) with the 2·5th and 97·5th percentiles of those 250 draws. Findings: While ORS use among children with diarrhoea increased in some countries from 2000 to 2017, coverage remained below 50% in the majority (62·6%; 12 417 of 19 823) of second administrative-level units and an estimated 6 519 000 children (95% UI 5 254 000–7 733 000) with diarrhoea were not treated with any form of ORT in 2017. Increases in ORS use corresponded with declines in RHF in many locations, resulting in relatively constant overall O
Published: 2020

14. Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

Author: Burstein, R., Henry, N. J., Collison, M. L., Marczak, L. B., Sligar, A., Watson, S., Marquez, N., Abbasalizad-Farhangi, M., Abbasi, M., Abd-Allah, F., Abdoli, A., Abdollahi, M., Abdollahpour, I., Abdulkader, R. S., Abrigo, M. R. M., Acharya, D., Adebayo, O. M., Adekanmbi, V., Adham, D., Afshari, M., Aghaali, M., Ahmadi, K., Ahmadi, M., Ahmadpour, E., Ahmed, R., Akal, C. G., Akinyemi, J. O., Alahdab, F., Alam, N., Alamene, G. M., Alene, K. A., Alijanzadeh, M., Alinia, C., Alipour, V., Aljunid, S. M., Almalki, M. J., Al-Mekhlafi, H. M., Altirkawi, K., Alvis-Guzman, N., Amegah, A. K., Amini, S., Amit, A. M. L., Anbari, Z., Androudi, S., Anjomshoa, M., Ansari, F., Antonio, C. A. T., Arabloo, J., Arefi, Z., Aremu, O., Armoon, B., Arora, A., Artaman, A., Asadi, A., Asadi-Aliabadi, M., Ashraf-Ganjouei, A., Assadi, R., Ataeinia, B., Atre, S. R., Quintanilla, B. P. A., Ayanore, M. A., Azari, S., Babaee, E., Babazadeh, A., Badawi, A., Bagheri, S., Bagherzadeh, M., Baheiraei, N., Balouchi, A., Barac, A., Bassat, Q., Baune, B. T., Bayati, M., Bedi, N., Beghi, E., Behzadifar, M., Belay, Y. B., Bell, B., Bell, M. L., Berbada, D. A., Bernstein, R. S., Bhattacharjee, N. V., Bhattarai, S., Bhutta, Z. A., Bijani, A., Bohlouli, S., Breitborde, N. J. K., Britton, G., Browne, A. J., Nagaraja, S. B., Busse, R., Butt, Z. A., Car, J., CÃ¡rdenas, R., CastaÃ±eda-Orjuela, C. A., Cerin, E., Chanie, W. F., Chatterjee, P., Chu, D. -T, Cooper, C., Costa, V. M., Dalal, Koustuv, Dandona, L., Dandona, R., Daoud, F., Daryani, A., Das Gupta, R., Davis, I., Davis Weaver, N., Davitoiu, D. V., De Neve, J. -W, Demeke, F. M., Demoz, G. T., Deribe, K., Desai, R., Deshpande, A., Desyibelew, H. D., Dey, S., Dharmaratne, S. D., Dhimal, M., Diaz, D., Doshmangir, L., Duraes, A. R., Dwyer-Lindgren, L., Earl, L., Ebrahimi, R., Ebrahimpour, S., Effiong, A., Eftekhari, A., Ehsani-Chimeh, E., El Sayed, I., El Sayed Zaki, M., El Tantawi, M., El-Khatib, Z., Emamian, M. H., Enany, S., Eskandarieh, S., Eyawo, O., Ezalarab, M., Faramarzi, M., Fareed, M., Faridnia, R., Faro, A., Fazaeli, A. A., Fazlzadeh, M., Fentahun, N., Fereshtehnejad, S. -M, Fernandes, J. C., Filip, I., Fischer, F., Foigt, N. A., Foroutan, M., Francis, J. M., Fukumoto, T., Fullman, N., Gallus, S., Gebre, D. G., Gebrehiwot, T. T., Gebremeskel, G. G., Gessner, B. D., Geta, B., Gething, P. W., Ghadimi, R., Ghadiri, K., Ghajarzadeh, M., Ghashghaee, A., Gill, P. S., Gill, T. K., Golding, N., Gomes, N. G. M., Gona, P. N., Gopalani, S. V., Gorini, G., Goulart, B. N. G., Graetz, N., Greaves, F., Green, M. S., Guo, Y., Haj-Mirzaian, A., Hall, B. J., Hamidi, S., Haririan, H., Haro, J. M., Hasankhani, M., Hasanpoor, E., Hasanzadeh, A., Hassankhani, H., Hassen, H. Y., Hegazy, M. I., Hendrie, D., Heydarpour, F., Hird, T. R., Hoang, C. L., Hollerich, G., Rad, E. H., Hoseini-Ghahfarokhi, M., Hossain, N., Hosseini, M., Hosseinzadeh, M., Hostiuc, M., Hostiuc, S., Househ, M., Hsairi, M., Ilesanmi, O. S., Imani-Nasab, M. H., Iqbal, U., Irvani, S. S. N., Islam, N., Islam, S. M. S., JÃŒrisson, M., Balalami, N. J., Jalali, A., Javidnia, J., Jayatilleke, A. U., Jenabi, E., Ji, J. S., Jobanputra, Y. B., Johnson, K., Jonas, J. B., Shushtari, Z. J., Jozwiak, J. J., Kabir, A., Kahsay, A., Kalani, H., Kalhor, R., Karami, M., Karki, S., Kasaeian, A., Kassebaum, N. J., Keiyoro, P. N., Kemp, G. R., Khabiri, R., Khader, Y. S., Khafaie, M. A., Khan, E. A., Khan, J., Khan, M. S., Khang, Y. -H, Khatab, K., Khater, A., Khater, M. M., Khatony, A., Khazaei, M., Khazaei, S., Khazaei-Pool, M., Khubchandani, J., Kianipour, N., Kim, Y. J., Kimokoti, R. W., Kinyoki, D. K., Kisa, A., Kisa, S., Kolola, T., Kosen, S., Koul, P. A., Koyanagi, A., Kraemer, M. U. G., Krishan, K., Krohn, K. J., Kugbey, N., Kumar, G. A., Kumar, M., Kumar, P., Kuupiel, D., Lacey, B., Lad, S. D., Lami, F. H., Larsson, A. O., Lee, P. H., Leili, M., Levine, A. J., Li, S., Lim, L. -L, Listl, S., Longbottom, J., Lopez, J. C. F., Lorkowski, S., Magdeldin, S., Abd El Razek, H. M., Abd El Razek, M. M., Majeed, A., Maleki, A., Malekzadeh, R., Malta, D. C., Mamun, A. A., Manafi, N., Manda, A. -L, Mansourian, M., Martins-Melo, F. R., Masaka, A., Massenburg, B. B., Maulik, P. K., Mayala, B. K., Mazidi, M., McKee, M., Mehrotra, R., Mehta, K. M., Meles, G. G., Mendoza, W., Menezes, R. G., Meretoja, A., Meretoja, T. J., Mestrovic, T., Miller, T. R., Miller-Petrie, M. K., Mills, E. J., Milne, G. J., Mini, G. K., Mir, S. M., Mirjalali, H., Mirrakhimov, E. M., Mohamadi, E., Mohammad, D. K., Darwesh, A. M., Mezerji, N. M. G., Mohammed, A. S., Mohammed, S., Mokdad, A. H., Molokhia, M., Monasta, L., Moodley, Y., Moosazadeh, M., Moradi, G., Moradi, M., Moradi, Y., Moradi-Lakeh, M., Moradinazar, M., Moraga, P., Morawska, L., Mosapour, A., Mousavi, S. M., Mueller, U. O., Muluneh, A. G., Mustafa, G., Nabavizadeh, B., Naderi, M., Nagarajan, A. J., Nahvijou, A., Najafi, F., Nangia, V., Ndwandwe, D. E., Neamati, N., Negoi, I., Negoi, R. I., Ngunjiri, J. W., Thi Nguyen, H. L., Nguyen, L. H., Nguyen, S. H., Nielsen, K. R., Ningrum, D. N. A., Nirayo, Y. L., Nixon, M. R., Nnaji, C. A., Nojomi, M., Noroozi, M., Nosratnejad, S., Noubiap, J. J., Motlagh, S. N., Ofori-Asenso, R., Ogbo, F. A., Oladimeji, K. E., Olagunju, A. T., Olfatifar, M., Olum, S., Olusanya, B. O., Oluwasanu, M. M., Onwujekwe, O. E., Oren, E., Ortega-Altamirano, D. D. V., Ortiz, A., Osarenotor, O., Osei, F. B., Osgood-Zimmerman, A. E., Otstavnov, S. S., Owolabi, M. O., Mahesh, P. A., Pagheh, A. S., Pakhale, S., Panda-Jonas, S., Pandey, A., Park, E. -K, Parsian, H., Pashaei, T., Patel, S. K., Pepito, V. C. F., Pereira, A., Perkins, S., Pickering, B. V., Pilgrim, T., Pirestani, M., Piroozi, B., Pirsaheb, M., Plana-Ripoll, O., Pourjafar, H., Puri, P., Qorbani, M., Quintana, H., Rabiee, M., Rabiee, N., Radfar, A., Rafiei, A., Rahim, F., Rahimi, Z., Rahimi-Movaghar, V., Rahimzadeh, S., Rajati, F., Raju, S. B., Ramezankhani, A., Ranabhat, C. L., Rasella, D., Rashedi, V., Rawal, L., Reiner Jr, R. C., Renzaho, A. M. N., Rezaei, S., Rezapour, A., Riahi, S. M., Ribeiro, A. I., Roever, L., Roro, E. M., Roser, M., Roshandel, G., Roshani, D., Rostami, A., Rubagotti, E., Rubino, S., Sabour, S., Sadat, N., Sadeghi, E., Saeedi, R., Safari, Y., Safari-Faramani, R., Safdarian, M., Sahebkar, A., Salahshoor, M. R., Salam, N., Salamati, P., Salehi, F., Zahabi, S. S., Salimi, Y., Salimzadeh, H., Salomon, J. A., Sambala, E. Z., Samy, A. M., Santric Milicevic, M. M., Jose, B. P. S., Saraswathy, S. Y. I., Sarmiento-SuÃ¡rez, R., Sartorius, B., Sathian, B., Saxena, S., Sbarra, A. N., Schaeffer, L. E., Schwebel, D. C., Sepanlou, S. G., Seyedmousavi, S., Shaahmadi, F., Shaikh, M. A., Shams-Beyranvand, M., Shamshirian, A., Shamsizadeh, M., Sharafi, K., Sharif, M., Sharif-Alhoseini, M., Sharifi, H., Sharma, J., Sharma, R., Sheikh, A., Shields, C., Shigematsu, M., Shiri, R., Shiue, I., Shuval, K., Siddiqi, T. J., Silva, J. P., Singh, J. A., Sinha, D. N., Sisay, M. M., Sisay, S., Sliwa, K., Smith, D. L., Somayaji, R., Soofi, M., Soriano, J. B., Sreeramareddy, C. T., Sudaryanto, A., Sufiyan, M. B., Sykes, B. L., Sylaja, P. N., TabarÃ©s-Seisdedos, R., Tabb, K. M., Tabuchi, T., Taveira, N., Temsah, M. -H, Terkawi, A. S., Tessema, Z. T., Thankappan, K. R., Thirunavukkarasu, S., To, Q. G., Tovani-Palone, M. R., Tran, B. X., Tran, K. B., Ullah, I., Usman, M. S., Uthman, O. A., Vahedian-Azimi, A., Valdez, P. R., van Boven, J. F. M., Vasankari, T. J., Vasseghian, Y., Veisani, Y., Venketasubramanian, N., Violante, F. S., Vladimirov, S. K., Vlassov, V., Vos, T., Vu, G. T., Vujcic, I. S., Waheed, Y., Wakefield, J., Wang, H., Wang, Y., Wang, Y. -P, Ward, J. L., Weintraub, R. G., Weldegwergs, K. G., Weldesamuel, G. T., Westerman, R., Wiysonge, C. S., Wondafrash, D. Z., Woyczynski, L., Wu, A. -M, Xu, G., Yadegar, A., Yamada, T., Yazdi-Feyzabadi, V., Yilgwan, C. S., Yip, P., Yonemoto, N., Lebni, J. Y., Younis, M. Z., Yousefifard, M., Yousof, H. -AS. A., Yu, C., Yusefzadeh, H., Zabeh, E., Moghadam, T. Z., Bin Zaman, S., Zamani, M., Zandian, H., Zangeneh, A., Zerfu, T. A., Zhang, Y., Ziapour, A., Zodpey, S., Murray, C. J. L., Hay, S. I., Burstein, R., Henry, N. J., Collison, M. L., Marczak, L. B., Sligar, A., Watson, S., Marquez, N., Abbasalizad-Farhangi, M., Abbasi, M., Abd-Allah, F., Abdoli, A., Abdollahi, M., Abdollahpour, I., Abdulkader, R. S., Abrigo, M. R. M., Acharya, D., Adebayo, O. M., Adekanmbi, V., Adham, D., Afshari, M., Aghaali, M., Ahmadi, K., Ahmadi, M., Ahmadpour, E., Ahmed, R., Akal, C. G., Akinyemi, J. O., Alahdab, F., Alam, N., Alamene, G. M., Alene, K. A., Alijanzadeh, M., Alinia, C., Alipour, V., Aljunid, S. M., Almalki, M. J., Al-Mekhlafi, H. M., Altirkawi, K., Alvis-Guzman, N., Amegah, A. K., Amini, S., Amit, A. M. L., Anbari, Z., Androudi, S., Anjomshoa, M., Ansari, F., Antonio, C. A. T., Arabloo, J., Arefi, Z., Aremu, O., Armoon, B., Arora, A., Artaman, A., Asadi, A., Asadi-Aliabadi, M., Ashraf-Ganjouei, A., Assadi, R., Ataeinia, B., Atre, S. R., Quintanilla, B. P. A., Ayanore, M. A., Azari, S., Babaee, E., Babazadeh, A., Badawi, A., Bagheri, S., Bagherzadeh, M., Baheiraei, N., Balouchi, A., Barac, A., Bassat, Q., Baune, B. T., Bayati, M., Bedi, N., Beghi, E., Behzadifar, M., Belay, Y. B., Bell, B., Bell, M. L., Berbada, D. A., Bernstein, R. S., Bhattacharjee, N. V., Bhattarai, S., Bhutta, Z. A., Bijani, A., Bohlouli, S., Breitborde, N. J. K., Britton, G., Browne, A. J., Nagaraja, S. B., Busse, R., Butt, Z. A., Car, J., CÃ¡rdenas, R., CastaÃ±eda-Orjuela, C. 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Abstract: Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2âto end preventable child deaths by 2030âwe need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000â2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations. Â© 2019, The Author(s).
Published: 2019
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15. PP-174 Comparison of Toxoplasma gondii excreted-secreted antigens from cell and cell free media in induction of humoral immune response

Author: Daryani, A., primary, Kalani, H., additional, Sharif, M., additional, and Rafiei, A., additional
Published: 2011
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16. Movement trend of Toxoplasma gondii in different tissues of Balb/c after immunization with excretory-secretory antigens

Author: Dadimoghaddam, Y., Daryani, A., Kalani, H., Ehsan Ahmadpour, Sharif, M., Ziaei, H., and Sarvi, S.

17. Toxoplasma gondii: A review of excretory secretory antigens

Author: Daryani, A., Kalani, H., Sharif, M., Ziaei, H., Sarvi, S., and Ehsan Ahmadpour

18. Current and novel laboratory diagnostic methods for amebiasis

Author: Fakhar, M., Taghavi, M., Kalani, H., Montazeri, M., and Hajar ziaei

19. Comparison of eight cell-free media for maintenance of Toxoplasma gondii tachyzoites

Author: Kalani, H., Daryani, A., mehdi Sharif, Ahmadpour, E., Alizadeh, A., Nasrolahei, M., Sarvi, M., Kalani, F., and Faridnia, R.
Subjects: Tachyzoite, In vitro, parasitic diseases, Phosphate buffered saline, Toxoplasma gondii, lcsh:RC109-216, Normal saline, Survival time, lcsh:Infectious and parasitic diseases
Abstract: Background: Toxoplasmosis is considered as one of the most common infectious diseases caused by the protozoan parasite Toxoplasma gondii. Tachyzoite is the main form of Toxoplasma and continuously is maintained in cell culture or injected into the mice peritoneal cavity. This study was designed to evaluate the survival rate of RH strain of T. gondii tachyzoites in different cell free, nutrient and biological media at different temperatures. Methods: This experimental study was performed at the Toxoplasmosis Research Center, Mazandaran University of Medical Sciences, Sari, Iran, in 2010. One ml of each solution including hypotonic saline (0.3%), normal saline (0.85%), RPMI-1640 (RPMI), RPMI with 10% fetal bovine serum (FBS), RPMI with 20% FBS, ovine hydatid cyst fluid, pasteurized milk of cow, and phosphate buffered saline (PBS) along with 4×104 T. gondii tachyzoites were added to plate wells and incubated in 4 °C, 22 °C, 37 °C, and 37 °C under 5% CO2. The survival rate and viability assessment of parasites were performed daily and the results were analyzed using Univariate tests. Result: Tachyzoites survival rate in PBS (4 °C) and normal saline (4 °C) were considerably high, compared to other solutions in different conditions (P

20. Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author: Soufiane Boufous, Yousef Veisani, Mehran Asadi-Aliabadi, Sharath Burugina Nagaraja, Maziar Moradi-Lakeh, Getachew Mullu Kassa, Edward J Mills, Dimas Ria Angga Pribadi, William James Dangel, Mohamad-Hani Temsah, Catherine O. Johnson, Gregory A. Roth, Giuseppe Gorini, Fariborz Mansour-Ghanaei, Alberto Ortiz, Samad Azari, Assefa Ayalew Ayalew Ayalew Gebreslassie, Salime Goharinezhad, Stephanie R. M. Zimsen, Peng Zheng, Michael Assmus, Elisabetta Pupillo, Bach Xuan Tran, Lal B. Rawal, Narayanaswamy Venketasubramanian, Noushin Mohammadifard, Stephen S Lim, Ata Rafiee, Maria Inês Schmidt, Vincent C. Iannucci, Suzanne Lyn Barker-Collo, Leah E. Cahill, Tauseef Ahmad, Platon D. Lopukhov, Kazumasa Yamagishi, Abdullah Al Mamun, Iqbal R. F. Elyazar, Giovanni Damiani, Mohammad Hossein Bakhshaei, Mehdi Fazlzadeh, Virginia Núñez-Samudio, Alyssa Pennini, Dietrich Plass, Atkilt Esaiyas Etisso, Gebre Teklemariam Demoz, Alexandrea Watson, Arvin Haj-Mirzaian, Paul S Briant, Frank B. Osei, Blair R. Bumgarner, Maciej Banach, Ravensara S. Travillian, Kai-Lan Chang, Shirin Djalalinia, Hasan Yusefzadeh, Silvano Gallus, Seyyed Meysam Mousavi, Bernhard T. Baune, Aaron van Donkelaar, Azeem Majeed, Hans Kromhout, Robert Ancuceanu, Blessing J. Akombi, Pushpendra Singh, Nayu Ikeda, William M. Gardner, Zahid A Butt, Mohammad Abdollahi, Temesgen Yihunie Akalu, Rahman Shiri, Benn Sartorius, Ai-Min Wu, Bing Fang Hwang, Flavia M. Cicuttini, Hiroyasu Iso, Luis Camera, Amin Soheili, Félix Carvalho, Yun Jin Kim, Caleb Mackay Salpeter Irvine, Mehdi Mirzaei-Alavijeh, Iman Halvaei, Saqib Ali, Giulio Castelpietra, Catalina Liliana Andrei, Ali Kazemi Karyani, Parkes J Kendrick, Hamidreza Haririan, Lucas Guimarães Abreu, Mukhammad David Naimzada, Jeff T. 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Cross, Vera Marisa Costa, Eduarda Fernandes, Chandrashekhar T Sreeramareddy, Odgerel Chimed-Ochir, Sonia Rodríguez-Ramírez, Bo Norrving, Kerem Shuval, Jacob L. Stubbs, Muhammad Ali, Shuhei Nomura, Man Mohan Mehndiratta, Chisom Joyqueenet Akunna, Abdollah Mohammadian-Hafshejani, Navid Rabiee, Dana Bryazka, Hussen Mohammed, Asadollah Gholamian, Ashley Marks, Rizwan Kalani, Molly E. Herbert, Islam Y. Elgendy, Moritz U. G. Kraemer, Chuanhua Yu, Suzanne Polinder, Pascual R. Valdez, Jennifer Rickard, Kylie Ball, Turki Alanzi, Mohsen Bayati, Hamed Mirzaei, Christopher M Odell, Amira Shaheen, Ziad A. Memish, Thirunavukkarasu Sathish, Michael A. Piradov, Hamed Kalani, Lorenzo Monasta, Christopher S Yilgwan, Desalegn Getnet Demsie, Riaz Uddin, Rizwan Suliankatchi Abdulkader, Vinay Srinivasan, Hamid Ahmadieh, Claudio Alberto Dávila-Cervantes, Raffaele Palladino, Chukwudi A Nnaji, Mika Shigematsu, Stein Emil Vollset, Abbas Sheikhtaheri, Paulo A. Lotufo, Nasir Salam, Binyam Minuye Birihane, Mohammad Ali Mansournia, Tomislav Mestrovic, Samer Hamidi, Rajesh Sagar, Mayowa O. Owolabi, Kara Estep, Ester Cerin, Michael T. Chung, Simon Øverland, Amir Taherkhani, Sheng Chia Chung, Martin Amogre Ayanore, Nikolaos Dervenis, Joan B. Soriano, Tahereh Javaheri, Victor Adekanmbi, Seid Tiku Mereta, Gbenga A. Kayode, Christopher R. Cederroth, Razique Anwer, Rajan Nikbakhsh, Kaja Abbas, Fatemeh Heydarpour, Louisa Degenhardt, Tahiya Alam, Mohammad Miri, Alibek Mereke, David Laith Rawaf, Ippazio Cosimo Antonazzo, Erkin M. Mirrakhimov, Seyed Hossein Yahyazadeh Jabbari, Desta Debalkie Atnafu, Davide Sattin, Moslem Soofi, Edris Hasanpoor, Krittika Bhattacharyya, Mika Kivimäki, Nikolay Ivanovich Briko, Joanna L Whisnant, Christopher J L Murray, Simin Mouodi, Alize J. Ferrari, Damian Santomauro, Katrin Burkart, Tudorel Andrei, Alberto Baldasseroni, Hafiz Ansar Rasul Suleria, Valery L. Feigin, Nauman Khalid, Ewerton Cousin, S. Mohammad Sajadi, Francisco Rogerlândio Martins-Melo, Shankar M Bakkannavar, Themba G.G. Ginindza, Sadaf G. Sepanlou, Sheikh Mohammed Shariful Islam, Sanjay Basu, Getinet Ayano, Paula Moraga, Soheil Hassanipour, Jason A. Anderson, Catherine Bisignano, Iyad Sultan, Deepak Kumar Pasupula, Keivan Ahmadi, Fariba Dorostkar, Rajeev Gupta, David M. Pereira, Mustafa Z. Younis, Adel Spotin, Rasmus Havmoeller, Yeshambel T. Nigatu, Barthelemy Kuate Defo, Mithila Faruque, Alan D. Lopez, Shailesh Advani, Behshad Naghshtabrizi, Shane D. Morrison, Inga Dora Sigfusdottir, Konrad Pesudovs, Anna Gershberg Hayoon, Raaj Kishore Biswas, Reshmi Bhageerathy, H. Dean Hosgood, Giulia Carreras, Sarika Chaturvedi, James L. Fisher, In-Hwan Oh, G Anil Kumar, Christoph Nowak, Vijay Kumar Chattu, Puja C Rao, Marcel Ausloos, Ali Kabir, Rannveig Sigurvinsdottir, Leeberk Raja Inbaraj, Edgar Denova-Gutiérrez, Rafael Tabarés-Seisdedos, Minh Nguyen, Ashkan Afshin, Payman Salamati, Colin Angus, Mona M. 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Campos-Nonato, Biniyam Sahiledengle Geberemariyam, Godfrey Mutashambara Rwegerera, Alaa Badawi, James Leigh, Morteza Arab-Zozani, Kyle E. Simpson, Muluken Bekele Sorrie, Roghiyeh Faridnia, Vivekanand Jha, Tomasz Miazgowski, Aaron J Cohen, Chukwuma David Umeokonkwo, Alessandra Lugo, Adhanom Gebreegziabher Baraki, Akshaya Srikanth Bhagavathula, Caitlyn Steiner, Gholamreza Roshandel, Cuong Tat Nguyen, Tania G Sánchez-Pimienta, Ahamarshan Jayaraman Nagarajan, Laura Kemmer, Ihoghosa Osamuyi Iyamu, Seyedeh Zahra Masoumi, Vivian Chia-Rong Hsieh, Kris J. Krohn, Phoebe Anne Rhinehart, Sarah Wozniak, Sahar Saeedi Moghaddam, Kate E. LeGrand, Christian Kieling, Vahid Yazdi-Feyzabadi, Robin Room, Zelalem Nigussie Azene, Kelly Cercy, Paul H. Lee, Stanislav S. Otstavnov, Dinesh Bhandari, Rafael Alves Guimarães, Zemenu Tadesse Tessema, Aziz Sheikh, Michellr L. Bell, Marwa Rashad Salem, Kirsten E. Wiens, Emma U.R. Smith, Hassan Abolhassani, Cristiano Piccinelli, Kedir Hussein Abegaz, G.K. Mini, Christian Razo, Manuela L. Ferreira, Diego De Leo, Francesco Saverio Violante, Aristidis Tsatsakis, Zahra Sadat Dibaji Forooshani, Tea Lallukka, Dickson A. Amugsi, Anna Poznańska, Graeme J. Hankey, Kewal Krishan, Maryam Zamanian, Eirini Skiadaresi, Jai K Das, Felix Greaves, Tessa M. Pilz, Sameer Vali Gopalani, Mansour Ghafourifard, M. DeLang, Morteza Mahmoudi, Alton Lu, Brian J. Hall, Ravi Prakash Jha, David Edvardsson, Xiu Ju George Zhao, Farshad Farzadfar, Hadi Hassankhani, Samuel M. Ostroff, Gerhard Sulo, Keyghobad Ghadiri, Neeraj Bhala, Stefan Lorkowski, Mohammad Rabiee, Sivan Yegnanarayana Iyer Saraswathy, Amirhossein Sahebkar, Rashid Abdi Guled, Abdallah M. Samy, Roman Topor-Madry, Michal Grivna, Afsaneh Arzani, Ayesha Humayun, Simin Liu, Maryam Khayamzadeh, Davoud Adham, Ahad Bakhtiari, Shafiu Mohammed, Paolo Lauriola, Abbas Mosapour, Sophia Emmons-Bell, Khurshid Alam, Rajat Das Gupta, Matilde Leonardi, Muktar Beshir Ahmed, Jeffrey V. Lazarus, Mohamed M. 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S. B., Caetano Dos Santos, F. L., Camera, L. A., Elyazar, I. R. F., Ayalew Gebreslassie, A. A. A., Ginindza, T. G., Matin, B. K., Morgado-Da-Costa, J., Khaneghah, A. M., Mahesh, P. A., Toroudi, H. P., Syed, Z. Q., Salem, M. R., Skou, S. T., Tovani-Palone, M. R., Tudor Car, L. T., and Moghadam, T. Z.
Subjects: Male, Nutritional Sciences, Specific risk, Contaminación del Aire Interior, 030204 cardiovascular system & hematology, Socioeconomic Factor, systematic analysis, Global Health, Body Mass Index, Global Burden of Disease, Health Risk Behavior, Health Risk Behaviors, Disease studies, 0302 clinical medicine, Risk Factors, METABOLIC RISKS, 030212 general & internal medicine, 11 Medical and Health Sciences, Factores de Riesgo, 2. Zero hunger, education.field_of_study, Public health, Injuries, Public Health, Global Health, Social Medicine and Epidemiology, General Medicine, GBD, risck factors, attributable burden of disease, 3142 Public health care science, environmental and occupational health, 3. Good health, Relative risk, Environmental health, Health, Hypertension, Global Burden of Diseases, Injuries, Risk Factors, A990 Medicine and Dentistry not elsewhere classified, Female, Leading risk factors, Global Health Metrics, Cohort study, Human, medicine.medical_specialty, Substance-Related Disorders, Population, UNITED-STATES, Risk Assessment, DIET, ITC-HYBRID, 03 medical and health sciences, Life Expectancy, MORTALITY, DISABILITY, POLLUTION, CLUSTERS, SDG 3 - Good Health and Well-being, General & Internal Medicine, medicine, Humans, Global Burden of Disease Study, Risk factor, education, Global burden, business.industry, Risk Factor, Malnutrition, Klinisk medicin, Global Burden of Diseases, Environmental Exposure, medicine.disease, Enfermedades, purl.org/pe-repo/ocde/ford#3.02.00 [https], Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Years of potential life lost, Socioeconomic Factors, Risk factors, Disease study, Hyperglycemia, ITC-ISI-JOURNAL-ARTICLE, NA, Clinical Medicine, business, RA
Abstract: Background Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attributable burden of disease. Methods GBD 2019 estimated attributable mortality, years of life lost (YLLs), years of life lived with disability (YLDs), and disability-adjusted life-years (DALYs) for 87 risk factors and combinations of risk factors, at the global level, regionally, and for 204 countries and territories. GBD uses a hierarchical list of risk factors so that specific risk factors (eg, sodium intake), and related aggregates (eg, diet quality), are both evaluated. This method has six analytical steps. (1) We included 560 risk-outcome pairs that met criteria for convincing or probable evidence on the basis of research studies. 12 risk-outcome pairs included in GBD 2017 no longer met inclusion criteria and 47 risk-outcome pairs for risks already included in GBD 2017 were added based on new evidence. (2) Relative risks were estimated as a function of exposure based on published systematic reviews, 81 systematic reviews done for GBD 2019, and meta-regression. (3) Levels of exposure in each age-sex-location-year included in the study were estimated based on all available data sources using spatiotemporal Gaussian process regression, DisMod-MR 2.1, a Bayesian meta-regression method, or alternative methods. (4) We determined, from published trials or cohort studies, the level of exposure associated with minimum risk, called the theoretical minimum risk exposure level. (5) Attributable deaths, YLLs, YLDs, and DALYs were computed by multiplying population attributable fractions (PAFs) by the relevant outcome quantity for each age-sex-location-year. (6) PAFs and attributable burden for combinations of risk factors were estimated taking into account mediation of different risk factors through other risk factors. Across all six analytical steps, 30 652 distinct data sources were used in the analysis. Uncertainty in each step of the analysis was propagated into the final estimates of attributable burden. Exposure levels for dichotomous, polytomous, and continuous risk factors were summarised with use of the summary exposure value to facilitate comparisons over time, across location, and across risks. Because the entire time series from 1990 to 2019 has been re-estimated with use of consistent data and methods, these results supersede previously published GBD estimates of attributable burden. Findings The largest declines in risk exposure from 2010 to 2019 were among a set of risks that are strongly linked to social and economic development, including household air pollution; unsafe water, sanitation, and handwashing; and child growth failure. Global declines also occurred for tobacco smoking and lead exposure. The largest increases in risk exposure were for ambient particulate matter pollution, drug use, high fasting plasma glucose, and high body-mass index. In 2019, the leading Level 2 risk factor globally for attributable deaths was high systolic blood pressure, which accounted for 10.8 million (95% uncertainty interval [UI] 9.51-12.1) deaths (19.2% [16.9-21.3] of all deaths in 2019), followed by tobacco (smoked, second-hand, and chewing), which accounted for 8.71 million (8.12-9.31) deaths (15.4% [14.6-16.2] of all deaths in 2019). The leading Level 2 risk factor for attributable DALYs globally in 2019 was child and maternal malnutrition, which largely affects health in the youngest age groups and accounted for 295 million (253-350) DALYs (11.6% [10.3-13.1] of all global DALYs that year). The risk factor burden varied considerably in 2019 between age groups and locations. Among children aged 0-9 years, the three leading detailed risk factors for attributable DALYs were all related to malnutrition. Iron deficiency was the leading risk factor for those aged 10-24 years, alcohol use for those aged 25-49 years, and high systolic blood pressure for those aged 50-74 years and 75 years and older. Interpretation Overall, the record for reducing exposure to harmful risks over the past three decades is poor. Success with reducing smoking and lead exposure through regulatory policy might point the way for a stronger role for public policy on other risks in addition to continued efforts to provide information on risk factor harm to the general public. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.
Published: 2020

21. Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019

Author: Sorin Hostiuc, Shaun Wen Huey Lee, Jorge R. Ledesma, Carsten Flohr, Masoumeh Sadeghi, João Mauricio Castaldelli-Maia, Behzad Karami Matin, Cyrus Alinia, Mehdi Bohluli, Félix Carvalho, Yun Jin Kim, Catalina Liliana Andrei, Seyyed Meysam Mousavi, Bernhard T. Baune, Ehsan Ahmadpour, Dinh-Toi Chu, Beatrix Haddock, Gianfranco Alicandro, Vasily Vlassov, Mohammad Taghi Khodayari, Gianna Gayle Herrera Amul, Arash Tehrani-Banihashemi, Govinda Prasad Dhungana, Fereshteh Ansari, Michael K. Hole, Azeem Majeed, Iman Halvaei, Saqib Ali, Arianna Maever L. Amit, Tomas Y. Yeheyis, John S. Ji, Martin McKee, Jamileh Shadid, Leonardo Roever, Peng Jia, Ettore Beghi, Pablo M. Lavados, Young Eun Kim, Vahid Alipour, Sowmya J. Rao, Ahmad Daryani, Cathleen Keller, Ibrahim Abdollahpour, Nicole K. DeCleene, Ebrahim Babaee, Saman Esmaeilnejad, Boris Bikbov, William M. Gardner, Lydia M. Haile, Luca Ronfani, Azalea M. Thomson, Irena Ilic, Ruth W. Kimokoti, Yingxi Zhao, Guoqing Hu, Mehran Shams-Beyranvand, Ilais Moreno Velásquez, Nathaniel J. Henry, Brijesh Sathian, Daniel Kim, Peter Memiah, Mohammad Hadi Abbasi, Andrea Farioli, Zahra Kamiab, Bolajoko O. Olusanya, Matthew C. Doxey, Tommi Vasankari, Hamideh Salimzadeh, Luisa Sorio Flor, Priya Rathi, Shanshan Li, Tanvir M. Huda, Dillon O Sylte, Rosario Cárdenas, Agegnehu Bante, Helen Ippolito, Alyssa Acebedo, Jeffrey D. Stanaway, Anwar Faraj, João Pedro Silva, Amin Mousavi Khaneghah, Pushpendra Kumar, Sangram Kishor Patel, Josephine W. Ngunjiri, Holly E. Erskine, Eugene Sobngwi, Filippo Ariani, Shane D. Morrison, Mohammad Aghaali, Meghan D. Mooney, Vera Marisa Costa, Palash Chandra Banik, Rupak Desai, Ken Takahashi, Maigeng Zhou, Morteza Oladnabi, Bogdan Oancea, Daniela Ribeiro, Mohammad Farahmand, Irmina Maria Michalek, Yetunde O. John-Akinola, Khem Narayan Pokhrel, Emilie R Maddison, Syed Mohamed Aljunid, Damian G. Hoy, Hosni Salem, V. Prakash, Shuhei Nomura, Inga Dora Sigfusdottir, Anders Larsson, Sharareh Eskandarieh, Abdollah Mohammadian-Hafshejani, Somayeh Bohlouli, Joana Morgado-da-Costa, Siamak Sabour, Theo Vos, Han Yong Wunrow, Khaled Khatab, Alireza Zangeneh, Ann Kristin Knudsen, Marissa B Reitsma, Hannah J. Henrikson, Randah R. Hamadeh, Tuomo J. Meretoja, Ireneous N. Soyiri, Giuseppe Grosso, Ziyad Al-Aly, Taraneh Yousefinezhadi, Joseph L Ward, Roba Khundkar, Ricardo Santiago Gomez, Reza Malekzadeh, John J. McGrath, Sandra B. Munro, Shahin Soltani, Amy E. Peden, Rufus Akinyemi, Marcel Ausloos, Naohiro Yonemoto, Bogdan Wojtyniak, Ahmad Ghashghaee, Guilherme Borges, Sadia Bibi, Farhad Islami, Hamed Mirzaei, Mohammad Ali Sahraian, M. Ashworth Dirac, Hosna Janjani, Kairat Davletov, Hermann Brenner, Yuichiro Yano, Elissa M. 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Bennitt, Maciej Banach, Antonio Biondi, Donal Bisanzio, Josip Car, Ronny Westerman, Shafiu Mohammed, Biniyam Sahiledengle Geberemariyam, Kenji Shibuya, Meghdad Pirsaheb, Milena Santric-Milicevic, Karen M. Tabb, Paula Moraga, Soheil Hassanipour, Hasan Yusefzadeh, Avina Vongpradith, Dara K. Mohammad, Ralph Maddison, Babak Moazen, Getachew Mullu Kassa, Rahman Shiri, Fernando Neves Hugo, Hmwe H Kyu, Zachary V Dingels, Florian Fischer, Valentin Yurievich Skryabin, Rafael Tabarés-Seisdedos, Massimo Cirillo, Nikita Otstavnov, Robert C. Reiner, Van C. Lansingh, Rodrigo Sarmiento-Suarez, Ashkan Afshin, Benjamin A Stark, Mohsen Abbasi-Kangevari, Natalie C. Galles, Behnam Heidari, Eun-Kee Park, Mohammad Ali Jahani, Suzanne Polinder, Mahalaqua Nazli Khatib, Farhad Jadidi-Niaragh, Amir Radfar, Mowafa Househ, Derrick A Bennett, Gaorui Guo, Hesam Ghiasvand, Taweewat Wiangkham, Tamás Joó, Cristiana Abbafati, Kathryn Mei Ming Lau, Anita K. Nandi, Miklós Szócska, Manasi Kumar, Eduardo A. 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L., Department of Public Health, Clinicum, Department of Neurosciences, HUS Comprehensive Cancer Center, Environmental Sciences, Public Health, Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Value, Affordability and Sustainability (VALUE), Microbes in Health and Disease (MHD), Sálfræðideild (HR), Department of Psychology (RU), Samfélagssvið (HR), School of Social Sciences (RU), Háskólinn í Reykjavík, Reykjavik University, GBD 2019 Diseases and Injuries Collaborator, Violante FS, Department of Earth Observation Science, Faculty of Geo-Information Science and Earth Observation, and UT-I-ITC-ACQUAL
Subjects: Male, Life expectancy, Disability-Adjusted Life Year, Diseases, Disease, communicable disease, systematic analysis, Global Burden of Disease, 0302 clinical medicine, 80 and over, Medicine, 10. No inequality, Child, 11 Medical and Health Sciences, injuries, Aged, 80 and over, education.field_of_study, Sjúkdómar, DEMENTIA, FALLS, General Medicine, Forvarnir, 3. Good health, Child, Preschool, Human, GBD, Population health, 03 medical and health sciences, SDG 3 - Good Health and Well-being, Humans, Global Burden of Disease Study, education, Aged, Spatial Analysis, Global burden, Disability, Prevention, DISABILITY, Infant, Spatial Analysi, Mortality rate, Global Burden of Disease, Diseases, Injuries, Systematic analysis, PREVENTION, Years of potential life lost, Risk factors, Disease study, ITC-ISI-JOURNAL-ARTICLE, RISK-FACTORS, Clinical Medicine, RA, Demography, Fötlun, Dánartíðni, Áhættuþættir, 030204 cardiovascular system & hematology, Risk Factors, Cause of Death, Global health, 030212 general & internal medicine, 1. No poverty, Disability-Adjusted Life Years, Public Health, Global Health, Social Medicine and Epidemiology, Middle Aged, 3142 Public health care science, environmental and occupational health, Adolescent, Adult, Age Distribution, Female, Infant, Newborn, Young Adult, Lýðheilsa, CLINICAL-TRIALS, Population, Settore MED/01 - Statistica Medica, diseases, ITC-HYBRID, Heilbrigðisvísindi, General & Internal Medicine, Mortality, Preschool, Disease burden, business.industry, Risk Factor, Klinisk medicin, Newborn, purl.org/pe-repo/ocde/ford#3.02.00 [https], Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, Áverkar, Systematic analysis, NA, business
Abstract: Publisher's version (útgefin grein), Background In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive and collectively exhaustive list of diseases and injuries. Methods GBD estimates incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) due to 369 diseases and injuries, for two sexes, and for 204 countries and territories. Input data were extracted from censuses, household surveys, civil registration and vital statistics, disease registries, health service use, air pollution monitors, satellite imaging, disease notifications, and other sources. Cause-specific death rates and cause fractions were calculated using the Cause of Death Ensemble model and spatiotemporal Gaussian process regression. Cause-specific deaths were adjusted to match the total all-cause deaths calculated as part of the GBD population, fertility, and mortality estimates. Deaths were multiplied by standard life expectancy at each age to calculate YLLs. A Bayesian meta-regression modelling tool, DisMod-MR 2.1, was used to ensure consistency between incidence, prevalence, remission, excess mortality, and cause-specific mortality for most causes. Prevalence estimates were multiplied by disability weights for mutually exclusive sequelae of diseases and injuries to calculate YLDs. We considered results in the context of the Socio-demographic Index (SDI), a composite indicator of income per capita, years of schooling, and fertility rate in females younger than 25 years. Uncertainty intervals (UIs) were generated for every metric using the 25th and 975th ordered 1000 draw values of the posterior distribution. Findings Global health has steadily improved over the past 30 years as measured by age-standardised DALY rates. After taking into account population growth and ageing, the absolute number of DALYs has remained stable. Since 2010, the pace of decline in global age-standardised DALY rates has accelerated in age groups younger than 50 years compared with the 1990-2010 time period, with the greatest annualised rate of decline occurring in the 0-9-year age group. Six infectious diseases were among the top ten causes of DALYs in children younger than 10 years in 2019: lower respiratory infections (ranked second), diarrhoeal diseases (third), malaria (fifth), meningitis (sixth), whooping cough (ninth), and sexually transmitted infections (which, in this age group, is fully accounted for by congenital syphilis; ranked tenth). In adolescents aged 10-24 years, three injury causes were among the top causes of DALYs: road injuries (ranked first), self-harm (third), and interpersonal violence (fifth). Five of the causes that were in the top ten for ages 10-24 years were also in the top ten in the 25-49-year age group: road injuries (ranked first), HIV/AIDS (second), low back pain (fourth), headache disorders (fifth), and depressive disorders (sixth). In 2019, ischaemic heart disease and stroke were the top-ranked causes of DALYs in both the 50-74-year and 75-years-and-older age groups. Since 1990, there has been a marked shift towards a greater proportion of burden due to YLDs from non-communicable diseases and injuries. In 2019, there were 11 countries where non-communicable disease and injury YLDs constituted more than half of all disease burden. Decreases in age-standardised DALY rates have accelerated over the past decade in countries at the lower end of the SDI range, while improvements have started to stagnate or even reverse in countries with higher SDI. Interpretation As disability becomes an increasingly large component of disease burden and a larger component of health expenditure, greater research and development investment is needed to identify new, more effective intervention strategies. With a rapidly ageing global population, the demands on health services to deal with disabling outcomes, which increase with age, will require policy makers to anticipate these changes. The mix of universal and more geographically specific influences on health reinforces the need for regular reporting on population health in detail and by underlying cause to help decision makers to identify success stories of disease control to emulate, as well as opportunities to improve. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd., Research reported in this publication was supported by the Bill & Melinda Gates Foundation; the University of Melbourne; Queensland Department of Health, Australia; the National Health and Medical Research Council, Australia; Public Health England; the Norwegian Institute of Public Health; St Jude Children's Research Hospital; the Cardiovascular Medical Research and Education Fund; the National Institute on Ageing of the National Institutes of Health (award P30AG047845); and the National Institute of Mental Health of the National Institutes of Health (award R01MH110163). The content is solely the responsibility of the authors and does not necessarily represent the official views of the funders. The authors alone are responsible for the views expressed in this Article and they do not necessarily represent the views, decisions, or policies of the institutions with which they are affiliated, the National Health Service (NHS), the National Institute for Health Research (NIHR), the UK Department of Health and Social Care, or Public Health England; the United States Agency for International Development (USAID), the US Government, or MEASURE Evaluation; or the European Centre for Disease Prevention and Control (ECDC). This research used data from the Chile National Health Survey 2003, 2009-10, and 2016-17. The authors are grateful to the Ministry of Health, the survey copyright owner, for allowing them to have the database. All results of the study are those of the authors and in no way committed to the Ministry. The Costa Rican Longevity and Healthy Aging Study project is a longitudinal study by the University of Costa Rica's Centro Centroamericano de Poblacion and Instituto de Investigaciones en Salud, in collaboration with the University of California at Berkeley. The original pre-1945 cohort was funded by the Wellcome Trust (grant 072406), and the 1945-55 Retirement Cohort was funded by the US National Institute on Aging (grant R01AG031716). The principal investigators are Luis Rosero-Bixby and William H Dow and co-principal investigators are Xinia Fernandez and Gilbert Brenes. The accuracy of the authors' statistical analysis and the findings they report are not the responsibility of ECDC. ECDC is not responsible for conclusions or opinions drawn from the data provided. ECDC is not responsible for the correctness of the data and for data management, data merging and data collation after provision of the data. ECDC shall not be held liable for improper or incorrect use of the data. The Health Behaviour in School-Aged Children (HBSC) study is an international study carried out in collaboration with WHO/EURO. The international coordinator of the 1997-98, 2001-02, 2005-06, and 2009-10 surveys was Candace Currie and the databank manager for the 1997-98 survey was Bente Wold, whereas for the following surveys Oddrun Samdal was the databank manager. A list of principal investigators in each country can be found on the HBSC website. Data used in this paper come from the 2009-10 Ghana Socioeconomic Panel Study Survey, which is a nationally representative survey of more than 5000 households in Ghana. The survey is a joint effort undertaken by the Institute of Statistical, Social and Economic Research (ISSER) at the University of Ghana and the Economic Growth Centre (EGC) at Yale University. It was funded by EGC. ISSER and the EGC are not responsible for the estimations reported by the analysts. The Palestinian Central Bureau of Statistics granted the researchers access to relevant data in accordance with license number SLN2014-3-170, after subjecting data to processing aiming to preserve the confidentiality of individual data in accordance with the General Statistics Law, 2000. The researchers are solely responsible for the conclusions and inferences drawn upon available data. Data for this research was provided by MEASURE Evaluation, funded by USAID. The authors thank the Russia Longitudinal Monitoring Survey, conducted by the National Research University Higher School of Economics and ZAO Demoscope together with Carolina Population Center, University of North Carolina at Chapel Hill and the Institute of Sociology, Russia Academy of Sciences for making data available. This paper uses data from the Bhutan 2014 STEPS survey, implemented by the Ministry of Health with the support of WHO; the Kuwait 2006 and 2014 STEPS surveys, implemented by the Ministry of Health with the support of WHO; the Libya 2009 STEPS survey, implemented by the Secretariat of Health and Environment with the support of WHO; the Malawi 2009 STEPS survey, implemented by Ministry of Health with the support of WHO; and the Moldova 2013 STEPS survey, implemented by the Ministry of Health, the National Bureau of Statistics, and the National Center of Public Health with the support of WHO. This paper uses data from Survey of Health, Ageing and Retirement in Europe (SHARE) Waves 1 (DOI:10.6103/SHARE. w1.700), 2 (10.6103/SHARE.w2.700), 3 (10.6103/SHARE.w3.700), 4 (10.6103/SHARE.w4.700), 5 (10.6103/SHARE.w5.700), 6 (10.6103/SHARE.w6.700), and 7 (10.6103/SHARE.w7.700); see Borsch-Supan and colleagues (2013) for methodological details. The SHARE data collection has been funded by the European Commission through FP5 (QLK6-CT-2001-00360), FP6 (SHARE-I3: RII-CT-2006-062193, COMPARE: CIT5-CT-2005-028857, SHARELIFE: CIT4-CT-2006-028812), FP7 (SHARE-PREP: GA N degrees 211909, SHARE-LEAP: GA N degrees 227822, SHARE M4: GA N degrees 261982) and Horizon 2020 (SHARE-DEV3: GA N degrees 676536, SERISS: GA N degrees 654221) and by DG Employment, Social Affairs & Inclusion. Additional funding from the German Ministry of Education and Research, the Max Planck Society for the Advancement of Science, the US National Institute on Aging (U01_AG09740-13S2, P01_AG005842, P01_AG08291, P30_AG12815, R21_AG025169, Y1-AG-4553-01, IAG_BSR06-11, OGHA_04-064, HHSN271201300071C), and from various national funding sources is gratefully acknowledged. This study has been realised using the data collected by the Swiss Household Panel, which is based at the Swiss Centre of Expertise in the Social Sciences. The project is financed by the Swiss National Science Foundation. The United States Aging, Demographics, and Memory Study is a supplement to the Health and Retirement Study (HRS), which is sponsored by the National Institute of Aging (grant number NIA U01AG009740). It was conducted jointly by Duke University and the University of Michigan. The HRS is sponsored by the National Institute on Aging (grant number NIA U01AG009740) and is conducted by the University of Michigan. This paper uses data from Add Health, a program project designed by J Richard Udry, Peter S Bearman, and Kathleen Mullan Harris, and funded by a grant P01-HD31921 from the Eunice Kennedy Shriver National Institute of Child Health and Human Development, with cooperative funding from 17 other agencies. Special acknowledgment is due to Ronald R Rindfuss and Barbara Entwisle for assistance in the original design. Information on how to obtain the Add Health data files is available on the Add Health website. No direct support was received from grant P01-HD31921 for this analysis. The data reported here have been supplied by the United States Renal Data System. The interpretation and reporting of these data are the responsibility of the authors and in no way should be seen as an official policy or interpretation of the US Government. Collection of data for the Mozambique National Survey on the Causes of Death 2007-08 was made possible by USAID under the terms of cooperative agreement GPO-A-00-08-000_D3-00. This manuscript is based on data collected and shared by the International Vaccine Institute (IVI) from an original study IVI conducted. L G Abreu acknowledges support from Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior (Brazil; finance code 001) and Conselho Nacional de Desenvolvimento Cientifico e Tecnologico (CNPq, a Brazilian funding agency). I N Ackerman was supported by a Victorian Health and Medical Research Fellowship awarded by the Victorian Government. O O Adetokunboh acknowledges the South African Department of Science and Innovation and the National Research Foundation. A Agrawal acknowledges the Wellcome Trust DBT India Alliance Senior Fellowship. S M Aljunid acknowledges the Department of Health Policy and Management, Faculty of Public Health, Kuwait University and International Centre for Casemix and Clinical Coding, Faculty of Medicine, National University of Malaysia for the approval and support to participate in this research project. M Ausloos, C Herteliu, and A Pana acknowledge partial support by a grant of the Romanian National Authority for Scientific Research and Innovation, CNDS-UEFISCDI, project number PN-III-P4-ID-PCCF-2016-0084. A Badawi is supported by the Public Health Agency of Canada. D A Bennett was supported by the NIHR Oxford Biomedical Research Centre. R Bourne acknowledges the Brien Holden Vision Institute, University of Heidelberg, Sightsavers, Fred Hollows Foundation, and Thea Foundation. G B Britton and I Moreno Velasquez were supported by the Sistema Nacional de Investigacion, SNI-SENACYT, Panama. R Buchbinder was supported by an Australian National Health and Medical Research Council (NHMRC) Senior Principal Research Fellowship. J J Carrero was supported by the Swedish Research Council (2019-01059). F Carvalho acknowledges UID/MULTI/04378/2019 and UID/QUI/50006/2019 support with funding from FCT/MCTES through national funds. A R Chang was supported by National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases grant K23 DK106515. V M Costa acknowledges the grant SFRH/BHD/110001/2015, received by Portuguese national funds through Fundacao para a Ciencia e Tecnologia, IP, under the Norma Transitaria DL57/2016/CP1334/CT0006. A Douiri acknowledges support and funding from the National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care South London at King's College Hospital NHS Foundation Trust and the Royal College of Physicians, and support from the NIHR Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust and King's College London. B B Duncan acknowledges grants from the Foundation for the Support of Research of the State of Rio Grande do Sul (IATS and PrInt) and the Brazilian Ministry of Health. H E Erskine is the recipient of an Australian NHMRC Early Career Fellowship grant (APP1137969). A J Ferrari was supported by a NHMRC Early Career Fellowship grant (APP1121516). H E Erskine and A J Ferrari are employed by and A M Mantilla-Herrera and D F Santomauro affiliated with the Queensland Centre for Mental Health Research, which receives core funding from the Queensland Department of Health. M L Ferreira holds an NHMRC Research Fellowship. C Flohr was supported by the NIHR Biomedical Research Centre based at Guy's and St Thomas' NHS Foundation Trust. M Freitas acknowledges financial support from the EU (European Regional Development Fund [FEDER] funds through COMPETE POCI-01-0145-FEDER-029248) and National Funds (Fundacao para a Ciencia e Tecnologia) through project PTDC/NAN-MAT/29248/2017. A L S Guimaraes acknowledges support from CNPq. C Herteliu was partially supported by a grant co-funded by FEDER through Operational Competitiveness Program (project ID P_40_382). P Hoogar acknowledges Centre for Bio Cultural Studies, Directorate of Research, Manipal Academy of Higher Education and Centre for Holistic Development and Research, Kalaghatagi. F N Hugo acknowledges the Visiting Professorship, PRINT Program, CAPES Foundation, Brazil. B-F Hwang was supported by China Medical University (CMU107-Z-04), Taichung, Taiwan. S M S Islam was funded by a National Heart Foundation Senior Research Fellowship and supported by Deakin University. R Q Ivers was supported by a research fellowship from the National Health and Medical Research Council of Australia. M Jakovljevic acknowledges the Serbian part of this GBD-related contribution was co-funded through Grant OI175014 of the Ministry of Education Science and Technological Development of the Republic of Serbia. P Jeemon was supported by a Clinical and Public Health intermediate fellowship (grant number IA/CPHI/14/1/501497) from the Wellcome Trust-Department of Biotechnology, India Alliance (2015-20). O John is a recipient of UIPA scholarship from University of New South Wales, Sydney. S V Katikireddi acknowledges funding from a NRS Senior Clinical Fellowship (SCAF/15/02), the Medical Research Council (MC_UU_12017/13, MC_UU_12017/15), and the Scottish Government Chief Scientist Office (SPHSU13, SPHSU15). C Kieling is a CNPq researcher and a UK Academy of Medical Sciences Newton Advanced Fellow. Y J Kim was supported by Research Management Office, Xiamen University Malaysia (XMUMRF/2018-C2/ITCM/00010). K Krishan is supported by UGC Centre of Advanced Study awarded to the Department of Anthropology, Panjab University, Chandigarh, India. M Kumar was supported by K43 TW 010716 FIC/NIMH. B Lacey acknowledges support from the NIHR Oxford Biomedical Research Centre and the BHF Centre of Research Excellence, Oxford. J V Lazarus was supported by a Spanish Ministry of Science, Innovation and Universities Miguel Servet grant (Instituto de Salud Carlos III [ISCIII]/ESF, the EU [CP18/00074]). K J Looker thanks the NIHR Health Protection Research Unit in Evaluation of Interventions at the University of Bristol, in partnership with Public Health England, for research support. S Lorkowski was funded by the German Federal Ministry of Education and Research (nutriCARD, grant agreement number 01EA1808A). R A Lyons is supported by Health Data Research UK (HDR-9006), which is funded by the UK Medical Research Council, Engineering and Physical Sciences Research Council, Economic and Social Research Council, NIHR (England), Chief Scientist Office of the Scottish Government Health and Social Care Directorates, Health and Social Care Research and Development Division (Welsh Government), Public Health Agency (Northern Ireland), British Heart Foundation, and Wellcome Trust. J J McGrath is supported by the Danish National Research Foundation (Niels Bohr Professorship), and the Queensland Health Department (via West Moreton HHS). P T N Memiah acknowledges support from CODESRIA. U O Mueller gratefully acknowledges funding by the German National Cohort Study BMBF grant number 01ER1801D. S Nomura acknowledges the Ministry of Education, Culture, Sports, Science, and Technology of Japan (18K10082). A Ortiz was supported by ISCIII PI19/00815, DTS18/00032, ISCIII-RETIC REDinREN RD016/0009 Fondos FEDER, FRIAT, Comunidad de Madrid B2017/BMD-3686 CIFRA2-CM. These funding sources had no role in the writing of the manuscript or the decision to submit it for publication. S B Patten was supported by the Cuthbertson & Fischer Chair in Pediatric Mental Health at the University of Calgary. G C Patton was supported by an aNHMRC Senior Principal Research Fellowship. M R Phillips was supported in part by the National Natural Science Foundation of China (NSFC, number 81371502 and 81761128031). A Raggi, D Sattin, and S Schiavolin were supported by grants from the Italian Ministry of Health (Ricerca Corrente, Fondazione Istituto Neurologico C Besta, Linea 4-Outcome Research: dagli Indicatori alle Raccomandazioni Cliniche). P Rathi and B Unnikrishnan acknowledge Kasturba Medical College, Mangalore, Manipal Academy of Higher Education, Manipal. A L P Ribeiro was supported by Brazilian National Research Council, CNPq, and the Minas Gerais State Research Agency, FAPEMIG. D C Ribeiro was supported by The Sir Charles Hercus Health Research Fellowship (#18/111) Health Research Council of New Zealand. D Ribeiro acknowledges financial support from the EU (FEDER funds through the Operational Competitiveness Program; POCI-01-0145-FEDER-029253). P S Sachdev acknowledges funding from the NHMRC of Australia Program Grant. A M Samy was supported by a fellowship from the Egyptian Fulbright Mission Program. M M Santric-Milicevic acknowledges the Ministry of Education, Science and Technological Development of the Republic of Serbia (contract number 175087). R Sarmiento-Suarez received institutional support from Applied and Environmental Sciences University (Bogota, Colombia) and ISCIII (Madrid, Spain). A E Schutte received support from the South African National Research Foundation SARChI Initiative (GUN 86895) and Medical Research Council. S T S Skou is currently funded by a grant from Region Zealand (Exercise First) and a grant from the European Research Council under the EU's Horizon 2020 research and innovation program (grant agreement number 801790). J B Soriano is funded by Centro de Investigacion en Red de Enfermedades Respiratorias, ISCIII. R Tabares-Seisdedos was supported in part by the national grant PI17/00719 from ISCIII-FEDER. N Taveira was partially supported by the European & Developing Countries Clinical Trials Partnership, the EU (LIFE project, reference RIA2016MC-1615). S Tyrovolas was supported by the Foundation for Education and European Culture, the Sara Borrell postdoctoral programme (reference number CD15/00019 from ISCIII-FEDER). S B Zaman received a scholarship from the Australian Government research training programme in support of his academic career., "Peer Reviewed"
Published: 2020

22. Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Author: Kinyoki, Damaris K., Ross, Jennifer M., Lazzar-Atwood, Alice, Munro, Sandra B., Schaeffer, Lauren E., Abbasalizad-Farhangi, Mahdieh, Abbasi, Masoumeh, Abbastabar, Hedayat, Abdelalim, Ahmed, Abdoli, Amir, Abdollahi, Mohammad, Abdollahpour, Ibrahim, Abdulkader, Rizwan Suliankatchi, Abebe, Nebiyu Dereje, Abebo, Teshome Abuka, Abegaz, Kedir Hussein, Abolhassani, Hassan, Abreu, Lucas Guimarães, Abrigo, Michael R. M., Abushouk, Abdelrahman I., Accrombessi, Manfred Mario Kokou, Acharya, Dilaram, Adabi, Maryam, Adebiyi, Akindele Olupelumi, Adedeji, Isaac Akinkunmi, Adekanmbi, Victor, Adeoye, Abiodun Moshood, Adetokunboh, Olatunji O., Adham, Davoud, Aduroja, Posi Emmanuel, Advani, Shailesh M., Afarideh, Mohsen, Aghaali, Mohammad, Agrawal, Anurag, Ahmad, Tauseef, Ahmadi, Keivan, Ahmadi, Sepideh, Ahmed, Muktar Beshir, Ahmed, Rushdia, Ajumobi, Olufemi, Akal, Chalachew Genet, Akalu, Temesgen Yihunie, Akinyemiju, Tomi, Akombi, Blessing, Al-Aly, Ziyad, Alam, Samiah, Alamene, Genet Melak, Alanzi, Turki M., Rabanal, Jacqueline Elizabeth Alcalde, Alema, Niguse Meles, Ali, Beriwan Abdulqadir, Ali, Muhammad, Alijanzadeh, Mehran, Alinia, Cyrus, Alipour, Vahid, Alizade, Hesam, Aljunid, Syed Mohamed, Almasi, Afshin, Almasi-Hashiani, Amir, Al-Mekhlafi, Hesham M., Al-Raddadi, Rajaa M., Altirkawi, Khalid, Alvis-Guzman, Nelson, Alvis-Zakzuk, Nelson J., Amare, Azmeraw T., Amegah, Adeladza Kofi, Amini, Saeed, Rarani, Mostafa Amini, Amiri, Fatemeh, Amit, Arianna Maever Loreche, Anber, Nahla Hamed, Andrei, Catalina Liliana, Ansari, Fereshteh, Ansari-Moghaddam, Alireza, Anteneh, Zelalem Alamrew, Antonio, Carl Abelardo T., Antriyandarti, Ernoiz, Anvari, Davood, Anwer, Razique, Appiah, Seth Christopher Yaw, Arabloo, Jalal, Arab-Zozani, Morteza, Araya, Ephrem Mebrahtu, Arefi, Zohreh, Aremu, Olatunde, Ärnlöv, Johan, Arzani, Afsaneh, Asadi-Aliabadi, Mehran, Asadi-Pooya, Ali A., Asgari, Samaneh, Asghari, Babak, Ashagre, Alebachew Fasil, Asrat, Anemaw A., Ataeinia, Bahar, Atalay, Hagos Tasew, Atnafu, Desta Debalkie, Atout, Maha Moh’d Wahbi, Ausloos, Marcel, Avokpaho, Euripide F. G. A., Awasthi, Ashish, Quintanilla, Beatriz Paulina Ayala, Ayanore, Martin Amogre, Aynalem, Yared A. Asmare, Azadmehr, Abbas, Azari, Samad, Azarian, Ghasem, Azene, Zelalem Nigussie, Babaee, Ebrahim, Badawi, Alaa, Badiye, Ashish D., Bahrami, Mohamad Amin, Baig, Atif Amin A., Bakhtiari, Ahad, Bakkannavar, Shankar M., Balakrishnan, Senthilkumar, Bali, Ayele Geleto, Banach, Maciej, Banik, Palash Chandra, Baradaran-Seyed, Zahra, Baraki, Adhanom Gebreegziabher, Barboza, Miguel A., Bärnighausen, Till Winfried, Barua, Lingkan, Basaleem, Huda, Basu, Sanjay, Bayati, Mohsen, Bayih, Mulat Tirfie, Baynes, Habtamu Wondifraw, Bedi, Neeraj, Behzadifar, Masoud, Behzadifar, Meysam, Bekele, Yibeltal Alemu, Bennett, Derrick A., Berbada, Dessalegn Ajema, Berhe, Kidanemaryam, Berhe, Abadi Kidanemariam, Berman, Adam E., Bernstein, Robert S., Bhageerathy, Reshmi, Bhandari, Dinesh, Bharadwaj, Pankaj, Bhattacharjee, Natalia V., Bhattacharyya, Krittika, Bijani, Ali, Bikbov, Boris, Bilano, Ver, Bililign, Nigus, Sayeed, Muhammad Shahdaat Bin, Birara, Setognal, Birhane, Minuye Biniam Biniam, Birhanu, Minyichil, Biswas, Raaj Kishore, Bitew, Zebenay Workneh, Bogale, Kassawmar Angaw, Bohlouli, Somayeh, Bolla, Srinivasa Rao, Boloor, Archith, Borzì, Antonio M., Borzouei, Shiva, Brady, Oliver J., Bragazzi, Nicola Luigi, Braithwaite, Dejana, Briko, Nikolay Ivanovich, Britton, Gabrielle, Budhathoki, Shyam S., Nagaraja, Sharath Burugina, Busse, Reinhard, Butt, Zahid A., Cahuana-Hurtado, Lucero, Cámera, Luis Alberto, Campos-Nonato, Ismael R., Cano, Jorge, Car, Josip, Cárdenas, Rosario, Carrero, Juan J., Carvalho, Félix, Castaldelli-Maia, João Mauricio, Castañeda-Orjuela, Carlos A., Castro, Franz, Cerin, Ester, Chansa, Collins, Charan, Jaykaran, Chatterjee, Pranab, Chattu, Vijay Kumar, Chauhan, Bal Govind, Chavshin, Ali Reza, Chehrazi, Mohammad, Chichiabellu, Tesfaye Yitna, Chin, Ken Lee, Christopher, Devasahayam J., Chu, Dinh-Toi, Cicuttini, Flavia M., Collison, Michael L., Cork, Michael A., Cormier, Natalie, Cortesi, Paolo Angelo, Costa, Vera M., Dadi, Abel Fekadu Fekadu, Dagnew, Baye, Dahlawi, Saad M. A., Damiani, Giovanni, Darwish, Amira Hamed, Daryani, Ahmad, Das, Jai K., Gupta, Rajat Das, Dávila-Cervantes, Claudio, Davis Weaver, Nicole, Leo, Diego De, Neve, Jan-Walter De, Demeke, Feleke Mekonnen, Demis, Asmamaw Bizuneh, Demissie, Dereje Bayissa, Demoz, Gebre Teklemariam, Denova-Gutiérrez, Edgar, Deribe, Kebede, Desai, Rupak, Desalegn, Beruk Berhanu, Desalew, Assefa, Deshpande, Aniruddha, Dey, Sagnik, Dharmaratne, Samath Dhamminda, Dhillon, Preeti, Dhimal, Meghnath, Dhungana, Govinda Prasad, Nasab, Mostafa Dianati, Diaz, Daniel, Forooshani, Zahra Sadat Dibaji, Dinsa, Girmaye Deye, Dipeolu, Isaac Oluwafemi, Djalalinia, Shirin, Do, Hoa Thi, Do, Huyen Phuc, Doku, Paul Narh, Dorostkar, Fariba, Doshmangir, Leila, Dubey, Manisha, Adema, Bereket Duko, Dunachie, Susanna J., Duncan, Bruce B., Cousin, Ewerton, Durães, Andre R., Earl, Lucas, Leylabadlo, Hamed Ebrahimzadeh, Eftekhari, Aziz, El Sayed, Iman, El Sayed Zaki, Maysaa, El Tantawi, Maha, Elbarazi, Iffat, Elemineh, Demelash Abewa, El-Jaafary, Shaimaa I., El-Khatib, Ziad, Elsharkawy, Aisha, El-Sherbiny, Yasser Mohamed, Elyazar, Iqbal R. F., Emamian, Mohammad Hassan, Enany, Shymaa, Endalew, Daniel Adane, Endalifer, Melese Linger, Eskandari, Khalil, Eskandarieh, Sharareh, Esmaeilnejad, Saman, Esteghamati, Alireza, Etemadi, Arash, Etisso, Atkilt Esaiyas, Fanzo, Jessica, Farahmand, Mohammad, Faraj, Anwar, Farashi, Sajjad, Fareed, Mohammad, Farioli, Andrea, Faro, Andre, Farzadfar, Farshad, Farzam, Hossein, Fatima, Syeda Sadia, Fattahi, Nazir, Fauk, Nelsensius Klau, Fazaeli, Ali Akbar, Fentahun, Netsanet, Ferede, Tomas Y., Fereshtehnejad, Seyed-Mohammad, Fernandes, Eduarda, Fernandes, João C., Feyissa, Garumma Tolu, Filip, Irina, Fischer, Florian, Flohr, Carsten, Foigt, Nataliya A., Folayan, Morenike Oluwatoyin, Fomenkov, Artem Alekseevich, Foroutan, Masoud, Förster, Jana, Francis, Joel Msafiri, Fukumoto, Takeshi, Gayesa, Reta Tsegaye, Geberemariyam, Biniyam Sahiledengle, Gebrehiwot, Tsegaye Tewelde, Gebremariam, Hadush, Gebremariam, Kidane Tadesse, Gebremedhin, Ketema Bizuwork Bizuwork, Gebremeskel, Gebreamlak Gebremedhn, Gebreslassie, Assefa Ayalew Ayalew, Gebretsadik, Gebretsadkan G. G., Gedefaw, Getnet Azeze, Geramo, Yilma Chisha Dea, Gesesew, Hailay Abrha, Geta, Birhanu, Getenet, Agegnehu Bante, Gezae, Kebede Embaye, Ghaffarifar, Fatemeh, Ghafourifard, Mansour, Ghajar, Alireza, Ghajarzadeh, Mahsa, Ghashghaee, Ahmad, Ghiasvand, Hesam, Gholamian, Asadollah, Gilani, Syed Amir, Gill, Tiffany K., Ginawi, Ibrahim Abdelmageed, Goli, Srinivas, Gomes, Nelson G. M., Gopalani, Sameer Vali, Goudarzi, Houman, Goulart, Alessandra C., Govindakarnavar, Arunkumar, Grada, Ayman, Grivna, Michal, Guimarães, Rafael Alves, Guled, Rashid Abdi, Guo, Yuming, Gupta, Rahul, Gupta, Rajeev, Hafezi-Nejad, Nima, Haile, Michael Tamene, Haj-Mirzaian, Arvin, Haj-Mirzaian, Arya, Hall, Brian J., Halvaei, Iman, Hamadeh, Randah R., Hamidi, Yadollah, Handiso, Demelash Woldeyohannes, Hankey, Graeme J., Haririan, Hamidreza, Hariyani, Ninuk, Hasaballah, Ahmed I., Hasan, Md. Mehedi, Hasankhani, Milad, Hasanpoor, Edris, Hasanzadeh, Amir, Hashemian, Maryam, Hassanipour, Soheil, Hassen, Hamid Yimam, Havmoeller, Rasmus, Hawkes, Corinna, Hayat, Khezar, Hayelom, Desta Haftu, Heidari, Behnam, Heidari-Soureshjani, Reza, Hendrie, Delia, Henok, Andualem, Henry, Nathaniel J., Herrero, Mario, Herteliu, Claudiu, Heydarpour, Fatemeh, de Hidru, Hagos D., Hoang, Chi Linh, Hoek, Hans W., Hole, Michael K., Holla, Ramesh, Hollerich, Gillian, Rad, Enayatollah Homaie, Hong, Sung Hwi, Hoogar, Praveen, Horino, Masako, Hossain, Naznin, Hosseini, Mostafa, Hosseinzadeh, Mehdi, Hostiuc, Mihaela, Hostiuc, Sorin, Househ, Mowafa, Hsairi, Mohamed, Hu, Guoqing, Huda, Tanvir M., Humayun, Ayesha, Hwang, Bing-Fang, Ibitoye, Segun Emmanuel, Ilesanmi, Olayinka Stephen, Ilic, Milena D., Imani-Nasab, Mohammad Hasan, Inbaraj, Leeberk Raja, Iqbal, Usman, Irvani, Seyed Sina Naghibi, Islam, Sheikh Mohammed Shariful, Iwu, Chidozie C. D., Iwu, Chinwe Juliana, Izadi, Neda, Jaafari, Jalil, Jaca, Anelisa, Jadidi-Niaragh, Farhad, Balalami, Nader Jafari, Jafarinia, Morteza, Jahani, Mohammad Ali, Jakovljevic, Mihajlo, Jalali, Amir, Jalilian, Farzad, Jayatilleke, Achala Upendra, Jeemon, Panniyammakal, Jehan, Fyezah, Jenabi, Ensiyeh, Jha, Ravi Prakash, Jha, Vivekanand, Ji, John S., Jia, Peng, John, Oommen, John-Akinola, Yetunde O., Johnson, Kimberly B., Jonas, Jost B., Joseph, Nitin, Joukar, Farahnaz, Jozwiak, Jacek Jerzy, Jungari, Suresh Banayya, Jürisson, Mikk, Kabir, Ali, Kabir, Zubair, Kahsay, Amaha, Kahssay, Molla, Kalani, Hamed, Kalankesh, Leila L., Kalhor, Rohollah, Kamiab, Zahra, Kanchan, Tanuj, Kapil, Umesh, Kapoor, Neeti, Karami, Manoochehr, Matin, Behzad Karami, Karch, André, Karim, Mohd A., Karki, Surendra, Kasaeian, Amir, Kasahun, Gebremicheal Gebreslassie, Kasaye, Habtamu Kebebe, Kassa, Tesfaye Dessale, Kassaye, Hagazi Gebremedhin, Kassebaum, Nicholas J., Karyani, Ali Kazemi, Kengne, Andre Pascal, Ketema, Daniel Bekele, Khader, Yousef Saleh, Khafaie, Morteza Abdullatif, Khaksarian, Mojtaba, Khalid, Nauman, Khalil, Ibrahim A., Khalilov, Rovshan, Khan, Asad, Khan, Ejaz Ahmad, Khan, Md Nuruzzaman, Khan, Mohammad Saud, Khan, Muhammad Shahzeb, Khatab, Khaled, Khater, Amir, Khater, Mona M., Khatib, Mahalqua Nazli, Khayamzadeh, Maryam, Khazaei-Pool, Maryam, Khazaei, Mohammad, Khazaei, Salman, Khodayari, Mohammad Taghi, Khosravi, Mohammad Hossein, Khundkar, Roba, Kiadaliri, Ali, Kianipour, Neda, Kiirithio, Daniel N., Kim, Yun Jin, Kimokoti, Ruth W., Kisa, Adnan, Kisa, Sezer, Kolola, Tufa, Komaki, Hamidreza, Kondlahalli, Shivakumar K. M., Koolivand, Ali, Koul, Parvaiz A., Koyanagi, Ai, Kraemer, Moritz U. G., Krishan, Kewal, Krohn, Kris J., Kugbey, Nuworza, Kumar, Manasi, Kumar, Pushpendra, Kumar, Vivek, Kurmi, Om P., Kuti, Oluwatosin, Vecchia, Carlo La, Lacey, Ben, Lad, Deepesh P., Lal, Aparna, Lal, Dharmesh Kumar, Lami, Faris Hasan, Lamichhane, Prabhat, Lang, Justin J., Lansingh, Van C., Lasrado, Savita, Lebedev, Georgy, Lee, Paul H., Lee, Shaun Wen Huey, Leili, Mostafa, Letourneau, Ian D., Lewycka, Sonia, Li, Shanshan, Lim, Lee-Ling, Linn, Shai, Liu, Shiwei, Liu, Simin, Lodha, Rakesh, Longbottom, Joshua, Lopez, Jaifred Christian F., Lorkowski, Stefan, Macarayan, Erlyn Rachelle King, Madadin, Mohammed, El Razek, Hassan Magdy Abd, El Razek, Muhammed Magdy Abd, Maghavani, Dhaval P., Mahasha, Phetole Walter, Mahotra, Narayan Bahadur, Maled, Venkatesh, Maleki, Afshin, Maleki, Shokofeh, Malta, Deborah Carvalho, Manafi, Ali, Manafi, Farzad, Manafi, Navid, Manohar, Narendar Dawanu, Mansour-Ghanaei, Fariborz, Mansouri, Borhan, Mansournia, Mohammad Ali, Mapoma, Chabila Christopher, Marami, Dadi, Marczak, Laurie B., Arnedo, Carlos Alberto Marrugo, Martins-Melo, Francisco Rogerlândio, Masaka, Anthony, Massenburg, Benjamin Ballard, Maulik, Pallab K., Mayala, Benjamin K., Mazidi, Mohsen, Mehndiratta, Man Mohan, Mehri, Freshteh, Mehta, Kala M., Meitei, Wahengbam Bigyananda, Mekonnen, Fantahun Ayenew, Mekonnen, Teferi, Meles, Gebrekiros Gebremichael, Meles, Hagazi Gebre, Melese, Addisu, Mendoza, Walter, Menezes, Ritesh G., Mengesha, Meresa Berwo, Mensah, George A., Meretoja, Tuomo J., Miazgowski, Tomasz, Kostova, Neda Milevska, Miller, Ted R., Mills, Edward J., Mini, G. K., Mir, Seyed Mostafa, Miri, Mohammad, Mirjalali, Hamed, Mirrakhimov, Erkin M., Mirzaei, Hamed, Mirzaei, Maryam, Mirzaei, Roya, Mirzaei-Alavijeh, Mehdi, Mithra, Prasanna, Moazen, Babak, Mohamadi, Efat, Mohamadi-Bolbanabad, Amjad, Mohammad, Karzan Abdulmuhsin, Mohammad, Yousef, Mohammad, Dara K., Darwesh, Aso Mohammad, Mezerji, Naser Mohammad Gholi, Mohammadian-Hafshejani, Abdollah, Mohammadnia-Afrouzi, Mousa, Mohammadoo-Khorasani, Milad, Mohammadpourhodki, Reza, Mohammed, Salahuddin, Mohammed, Shafiu, Mohammed, Jemal Abdu, Mohammed, Ammas Siraj, Mohebi, Farnam, Mokari, Amin, Mokdad, Ali H., Montañez, Julio Cesar, Montero-Zamora, Pablo A., Moodley, Yoshan, Moossavi, Maryam, Moradi, Ghobad, Moradi, Masoud, Moradi, Yousef, Moradi-Joo, Mohammad, Moradi-Lakeh, Maziar, Moradpour, Farhad, Moradzadeh, Rahmatollah, Moraga, Paula, Morrison, Shane Douglas, Mosapour, Abbas, Mosser, Jonathan F., Mouodi, Simin, Khaneghah, Amin Mousavi, Mozaffarian, Dariush, Mueller, Ulrich Otto, Murray, Christopher J. L., Murthy, G. V. S., Musa, Kamarul Imran, Mustafa, Ghulam, Muthupandian, Saravanan, Nabavizadeh, Behnam, Naderi, Mehdi, Nadkarni, Girish N., Nagarajan, Ahamarshan Jayaraman, Naghavi, Mohsen, Naheed, Aliya, Naik, Gurudatta, Najafi, Farid, Nansseu, Jobert Richie, Narayan, K. M. Venkat, Nascimento, Bruno Ramos, Nayak, Vinod, Nazari, Javad, Ndwandwe, Duduzile Edith, Negoi, Ionut, Negoi, Ruxandra Irina, Ngunjiri, Josephine W., Nguyen, Cuong Tat, Nguyen, Huong Lan Thi, Nigatu, Dabere, Nigatu, Yeshambel T., Nikbakhsh, Rajan, Ningrum, Dina Nur Anggraini, Nnaji, Chukwudi A., Nong, Vuong Minh, Noubiap, Jean Jacques, Nowak, Christoph, Oancea, Bogdan, Ofori-Asenso, Richard, Oghenetega, Onome Bright, Oh, In-Hwan, Oladimeji, Olanrewaju, Oladnabi, Morteza, Olagunju, Andrew T., Olagunju, Tinuke O., Olusanya, Bolajoko Olubukunola, Olusanya, Jacob Olusegun, Oluwasanu, Mojisola Morenike, Omer, Muktar Omer, Onwujekwe, Obinna E., Asante, Kwaku Oppong, Oren, Eyal, Orisakwe, Orish Ebere, Ortiz, Alberto, Osarenotor, Osayomwanbo, Osgood-Zimmerman, Aaron E., Owolabi, Mayowa Ojo, P. A., Mahesh, Padubidri, Jagadish Rao, Pakshir, Keyvan, Pana, Adrian, Panda-Jonas, Songhomitra, Parsian, Hadi, Pashaei, Tahereh, Pasupula, Deepak Kumar, Patel, Sangram Kishor, Pathak, Ashish, Pathak, Mona, Pati, Sanghamitra, Patle, Ajay, Patton, George C., Paulos, Kebreab, Toroudi, Hamidreza Pazoki, Pepito, Veincent Christian Filipino, Perico, Norberto, Petri, William A., Pickering, Brandon V., Pigott, David M., Pirestani, Majid, Piroozi, Bakhtiar, Pirsaheb, Meghdad, Pokhrel, Khem Narayan, Postma, Maarten J., Pourjafar, Hadi, Pourmalek, Farshad, Kalhori, Reza Pourmirza, Pourshams, Akram, Poustchi, Hossein, Prada, Sergio I., Preotescu, Liliana, Pribadi, Dimas Ria Angga, Syed, Zahiruddin Quazi, Rabiee, Mohammad, Rabiee, Navid, Radfar, Amir, Rafiei, Alireza, Rahim, Fakher, Rahimi-Movaghar, Vafa, Rahman, Muhammad Aziz, Rahman, Sajjad ur, Rai, Rajesh Kumar, Rajabpour-Sanati, Ali, Rajati, Fatemeh, Ramezanzadeh, Kiana, Rana, Saleem Muhammad, Ranabhat, Chhabi Lal, Rao, Sowmya J., Rasella, Davide, Rashedi, Vahid, Rastogi, Prateek, Rathi, Priya, Rawaf, Salman, Rawaf, David Laith, Rawal, Lal, Ray, Sarah E., Remuzzi, Giuseppe, Renjith, Vishnu, Renzaho, Andre M. N., Resnikoff, Serge, Rezaei, Nima, Rezaeian, Shahab, Rezai, Mohammad Sadegh, Rezapour, Aziz, Riahi, Seyed Mohammad, Ribeiro, Ana Isabel, Rickard, Jennifer, Rodriguez, Alina, Roever, Leonardo, Roro, Elias Merdassa, Roshandel, Gholamreza, Rostami, Ali, Rubagotti, Enrico, Saad, Anas M., Saadatagah, Seyedmohammad, Sabde, Yogesh Damodar, Sabour, Siamak, Sadeghi, Ehsan, Sadeghi, Masoumeh, Safari, Saeed, Safari, Yahya, Safarpour, Hamid, Sagar, Rajesh, Sahebkar, Amirhossein, Sahraian, Mohammad Ali, Sajadi, S. Mohammad, Salahshoor, Mohammad Reza, Salam, Nasir, Salehi, Farkhonde, Zahabi, Saleh Salehi, Salem, Hosni, Salem, Marwa R. Rashad, Salimi, Yahya, Salimzadeh, Hamideh, Kafil, Hossein Samadi, Sambala, Evanson Zondani, Samy, Abdallah M., Santos, Itamar S., Jose, Bruno Piassi Sao, Saraswathy, Sivan Yegnanarayana Iyer, Sarker, Abdur Razzaque, Sartorius, Benn, Sarveazad, Arash, Sathian, Brijesh, Satpathy, Maheswar, Saxena, Sonia, Sayyah, Mehdi, Sbarra, Alyssa N., Schipp, Megan F., Schmidt, Maria Inês, Schutte, Aletta Elisabeth, Schwebel, David C., Senbeta, Anbissa Muleta, Senthilkumaran, Subramanian, Seyedmousavi, Seyedmojtaba, Shaahmadi, Faramarz, Shafaat, Omid, Shahabi, Saeed, Shaikh, Masood Ali, Shalash, Ali S., Shams-Beyranvand, Mehran, Shamshirian, Amir, Shamsizadeh, Morteza, Shannawaz, Mohammed, Sharafi, Kiomars, Sharif, Mehdi, Sharma, Rajesh, Shehata, Hatem Samir, Sheikhtaheri, Abbas, Shibuya, Kenji, Shiferaw, Wondimeneh Shibabaw, Shigematsu, Mika, Shin, Jae Il, Shiri, Rahman, Shirkoohi, Reza, Shiue, Ivy, Shuval, Kerem, Siabani, Soraya, Siddiqi, Tariq J., Sigfusdottir, Inga Dora, Silva, Diego Augusto Santos, Simonetti, Biagio, Singh, Ambrish, Singh, Pushpendra, Singh, Virendra, Singh, Jasvinder A., Singh, Pankaj Kumar, Sinha, Dhirendra Narain, Sintayehu, Yitagesu, Sisay, Malede Mequanent M., Soheili, Amin, Soleymani, Bija, Soltani, Farzaneh, Soltani, Shahin, Soriano, Joan B., Sorrie, Muluken Bekele, Soshnikov, Sergey, Soyiri, Ireneous N., Spotin, Adel, Sreeramareddy, Chandrashekhar T., Srivastava, Rajni Kant Kant, Starodubova, Antonina, Sudaryanto, Agus, Sufiyan, Mu’awiyyah Babale, Suleria, Hafiz Ansar Rasul, Sulo, Gerhard, Sunguya, Bruno F., Sykes, Bryan L., Tabarés-Seisdedos, Rafael, Tabuchi, Takahiro, Tadesse, Birkneh Tilahun, Taherkhani, Amir, Tamirat, Koku Sisay, Tassew, Segen Gebremeskel, Taveira, Nuno, Teklehaimanot, Berhane Fseha, Tekulu, Gebretsadkan Hintsa, Temsah, Mohamad-Hani, Terkawi, Abdullah Sulieman, Tessema, Zemenu Tadesse, Thomas, Nihal, Titova, Mariya Vladimirovna, Tlaye, Kenean Getaneh, Tohidinik, Hamid Reza, Tonelli, Marcello, Tovani-Palone, Marcos Roberto, Traini, Eugenio, Tran, Khanh Bao, Tripathi, Manjari, Uddin, Riaz, Ullah, Irfan, Unnikrishnan, Bhaskaran, Upadhyay, Era, Useh, Ushotanefe, Usman, Muhammad Shariq, Uthman, Olalekan A., Vacante, Marco, Vaezghasemi, Masoud, Valdez, Pascual R., VanderHeide, John, Varavikova, Elena, Varughese, Santosh, Vasankari, Tommi Juhani, Vasseghian, Yasser, Veisani, Yousef, Venkatesh, Srinivasaraghavan, Venketasubramanian, Narayanaswamy, Verma, Madhur, Vidale, Simone, Violante, Francesco S., Vlassov, Vasily, Vollmer, Sebastian, Vukovic, Rade, Waheed, Yasir, Wang, Haidong, Wang, Yafeng, Wang, Yuan-Pang, Weldesamuel, Girmay Teklay, Werdecker, Andrea, Wiangkham, Taweewat, Wiens, Kirsten E., Wijeratne, Tissa, Wolde, Haileab Fekadu, Wondafrash, Dawit Zewdu, Wonde, Tewodros Eshete, Wondmieneh, Adam Belay, Wu, Ai-Min, Xu, Gelin, Yadegar, Abbas, Yadollahpour, Ali, Jabbari, Seyed Hossein Yahyazadeh, Yamada, Tomohide, Yano, Yuichiro, Yaya, Sanni, Yazdi-Feyzabadi, Vahid, Yeshaneh, Alex, Yeshaw, Yigizie, Yeshitila, Yordanos Gizachew, Yilma, Mekdes Tigistu, Yip, Paul, Yonemoto, Naohiro, Yoon, Seok-Jun, Youm, Yoosik, Younis, Mustafa Z., Yousefi, Zabihollah, Yousof, Hebat-Allah Salah A., Yu, Chuanhua, Yusefzadeh, Hasan, Moghadam, Telma Zahirian, Zaki, Leila, Zaman, Sojib Bin, Zamani, Mohammad, Zamanian, Maryam, Zandian, Hamed, Zarafshan, Hadi, Zepro, Nejimu Biza, Zerfu, Taddese Alemu, Zewale, Taye Abuhay, Zhang, Yunquan, Zhang, Zhi-Jiang, Zhao, Xiu-Ju, Zodpey, Sanjay, Zomorodian, Kamiar, Zotor, Francis Bruno, Afshin, Ashkan, Hay, Simon I., LBD Double Burden of Malnutrition Collaborator, Violante FS, Adema, Bereket Duko, Yeshaw, Yigizie, LBD Double Burden of Malnutrition Collaborators, Instituto de Saúde Pública da Universidade do Porto, 10922180 - Schutte, Aletta Elisabeth, UAM. Departamento de Medicina, Instituto de Investigación Sanitaria Fundación Jiménez Díaz (IIS-FJD), Instituto de Investigación Sanitaria Hospital Universitario de La Princesa (IIS-IP), Veritati - Repositório Institucional da Universidade Católica Portuguesa, Biosciences, University of Helsinki, Clinicum, HUS Comprehensive Cancer Center, Institute for Molecular Medicine Finland, Department of Earth Observation Science, UT-I-ITC-ACQUAL, Faculty of Geo-Information Science and Earth Observation, Sálfræðideild (HR), Department of Psychology (RU), Samfélagssvið (HR), School of Social Sciences (RU), Háskólinn í Reykjavík, Reykjavik University, Instituto de Investigación Sanitaria Fundación Jiménez Díaz (ISS-FJD), Kinyoki, D, Ross, J, Lazzar-Atwood, A, Munro, S, Schaeffer, L, Abbasalizad-Farhangi, M, Abbasi, M, Abbastabar, H, Abdelalim, A, Abdoli, A, Abdollahi, M, Abdollahpour, I, Abdulkader, R, Abebe, N, Abebo, T, Abegaz, K, Abolhassani, H, Abreu, L, Abrigo, M, Abushouk, A, Accrombessi, M, 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A, Azari, S, Azarian, G, Azene, Z, Babaee, E, Badawi, A, Badiye, A, Bahrami, M, Baig, A, Bakhtiari, A, Bakkannavar, S, Balakrishnan, S, Bali, A, Banach, M, Banik, P, Baradaran-Seyed, Z, Baraki, A, Barboza, M, Barnighausen, T, Barua, L, Basaleem, H, Basu, S, Bayati, M, Bayih, M, Baynes, H, Bedi, N, Behzadifar, M, Bekele, Y, Bennett, D, Berbada, D, Berhe, K, Berhe, A, Berman, A, Bernstein, R, Bhageerathy, R, Bhandari, D, Bharadwaj, P, Bhattacharjee, N, Bhattacharyya, K, Bijani, A, Bikbov, B, Bilano, V, Bililign, N, Sayeed, M, Birara, S, Birhane, M, Birhanu, M, Biswas, R, Bitew, Z, Bogale, K, Bohlouli, S, Bolla, S, Boloor, A, Borzi, A, Borzouei, S, Brady, O, Bragazzi, N, Braithwaite, D, Briko, N, Britton, G, Budhathoki, S, Nagaraja, S, Busse, R, Butt, Z, Cahuana-Hurtado, L, Camera, L, Campos-Nonato, I, Cano, J, Car, J, Cardenas, R, Carrero, J, Carvalho, F, Castaldelli-Maia, J, Castaneda-Orjuela, C, Castro, F, Cerin, E, Chansa, C, Charan, J, Chatterjee, P, Chattu, V, Chauhan, B, Chavshin, A, Chehrazi, M, Chichiabellu, T, Chin, K, Christopher, D, Chu, D, Cicuttini, F, Collison, M, Cork, M, Cormier, N, Cortesi, P, Costa, V, Dadi, A, Dagnew, B, Dahlawi, S, Damiani, G, Darwish, A, Daryani, A, Das, J, Gupta, R, Davila-Cervantes, C, Davis Weaver, N, Leo, D, Neve, J, Demeke, F, Demis, A, Demissie, D, Demoz, G, Denova-Gutierrez, E, Deribe, K, Desai, R, Desalegn, B, Desalew, A, Deshpande, A, Dey, S, Dharmaratne, S, Dhillon, P, Dhimal, M, Dhungana, G, Nasab, M, Diaz, D, Forooshani, Z, Dinsa, G, Dipeolu, I, Djalalinia, S, Do, H, Doku, P, Dorostkar, F, Doshmangir, L, Dubey, M, Adema, B, Dunachie, S, Duncan, B, Duraes, A, Earl, L, Leylabadlo, H, Eftekhari, A, El Sayed, I, El Sayed Zaki, M, El Tantawi, M, Elbarazi, I, Elemineh, D, El-Jaafary, S, El-Khatib, Z, Elsharkawy, A, El-Sherbiny, Y, Elyazar, I, Emamian, M, Enany, S, Endalew, D, Endalifer, M, Eskandari, K, Eskandarieh, S, Esmaeilnejad, S, Esteghamati, A, Etemadi, A, Etisso, A, Fanzo, J, Farahmand, M, Faraj, A, Farashi, S, 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Subjects: Male, Local patterns, Double burden, Börn, Research & Experimental Medicine, Sjúkdómseinkenni, DOUBLE BURDEN, Childhood overweight, Lífefnafræði, Læknisfræði, 0302 clinical medicine, Syndemic, Child, 11 Medical and Health Sciences, under 5 years of age, General Medicine, 3. Good health, Geography, Medicine, Research & Experimental, Child, Preschool, Income, GROWTH, AFRICA, medicine.medical_specialty, Biochemistry & Molecular Biology, RJ, Medicina, Immunology, education, MODELS, wa_395, General Biochemistry, Genetics and Molecular Biology, Article, 03 medical and health sciences, Humans, Author Correction, Developing Countries, Poverty, Biology, LBD Double Burden of Malnutrition Collaborators, Demography, Science & Technology, Wasting Syndrome, Public health, MORTALITY, Infant, Næringarskortur, medicine.disease, Obesity, TRENDS, signs and symptoms, Social Class, Risk factors, Sameindalíffræði, ITC-ISI-JOURNAL-ARTICLE, UNDERNUTRITION, Human medicine, Clinical Medicine, 030217 neurology & neurosurgery, Pediatric Obesity, obesity, Offita, Áhættuþættir, Geographic Mapping, Overweight, RA0421, Global health, risk factors, 030212 general & internal medicine, Signs and symptoms, Wasting, Malnutrition, Global Burden of Diseases, Global Nutrition, low- and middle-income countries, 2. Zero hunger, 1. No poverty, Public Health, Global Health, Social Medicine and Epidemiology, A900 Others in Medicine and Dentistry, Childhood wasting, PREVALENCE, Chemistry, Mapping, Female, Lýðheilsa, medicine.symptom, Life Sciences & Biomedicine, GROWTH FAILURE, Nutritional Status, malnutrition, ITC-HYBRID, ws_115, children, Environmental health, medicine, Erfðafræði, wd_200, Malnutrition, Infant, Newborn, Klinisk medicin, Cell Biology, Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi, 3121 General medicine, internal medicine and other clinical medicine, NA
Abstract: Artículo con numerosos autores, sólo se mencionan el primero, los de la UAM y grupo colectivo, A double burden of malnutrition occurs when individuals, household members or communities experience both undernutrition and overweight. Here, we show geospatial estimates of overweight and wasting prevalence among children under 5 years of age in 105 low- and middle-income countries (LMICs) from 2000 to 2017 and aggregate these to policy-relevant administrative units. Wasting decreased overall across LMICs between 2000 and 2017, from 8.4% (62.3 (55.1–70.8) million) to 6.4% (58.3 (47.6–70.7) million), but is predicted to remain above the World Health Organization’s Global Nutrition Target of, This work was primarily supported by grant OPP1132415 from the Bill & Melinda Gates Foundation awarded to S.I.H.
Published: 2020

23. Mapping 123 million neonatal, infant and child deaths between 2000 and 2017

Author: Mohsen Bayati, Arvin Haj-Mirzaian, Mehran Asadi-Aliabadi, Maziar Moradi-Lakeh, Nasir Salam, Mohamad-Hani Temsah, Fatemeh Heydarpour, Davide Rasella, Kavumpurathu Raman Thankappan, Ghulam Mustafa, Sergey Konstantinovitch Vladimirov, Fereshteh Ansari, Dina Nur Anggraini Ningrum, Leonardo Roever, Oghenowede Eyawo, Koustuv Dalal, Ana-Laura Manda, Ritesh G. Menezes, Molly K. Miller-Petrie, Javad Yoosefi Lebni, Gebreamlak Gebremedhn Gebremeskel, Aziz Eftekhari, Oleguer Plana-Ripoll, Jon Wakefield, Sanjay Zodpey, Birhanu Geta, Amaha Kahsay, Edris Hasanpoor, Brijesh Sathian, Kala M. Mehta, Moritz U. G. Kraemer, Saeed Amini, Hesham M. Al-Mekhlafi, Abbas Yadegar, João Pedro Silva, Desmond Kuupiel, Anvar Asadi, Hamid Sharifi, Ebrahim Babaee, Dessalegn Ajema Berbada, Taddese Alemu Zerfu, Ian Davis, Mostafa Qorbani, Fatemeh Rajati, Samer Hamidi, Parvaiz A Koul, Foad Abd-Allah, Mojisola Oluwasanu, Syed Mohamed Aljunid, Elias Merdassa Roro, Mihaela Hostiuc, Robert S. Bernstein, Vahid Yazdi-Feyzabadi, Gebre Teklemariam Demoz, Irina Filip, Mu'awiyyah Babale Sufiyan, Amir Khater, Lidia Morawska, Sangram Kishor Patel, Robert C. Reiner, Joshua O. Akinyemi, Telma Zahirian Moghadam, Ali Akbar Fazaeli, Reza Malekzadeh, Olatunde Aremu, Mohammad Reza Salahshoor, Irfan Ullah, Gabrielle B. Britton, Gelin Xu, Nathaniel J Henry, Thomas R. Hird, Ronny Westerman, Vera Marisa Costa, Reza Assadi, Tiffany K. Gill, Chhabi Lal Ranabhat, Meysam Olfatifar, Sezer Kisa, Grant Rodgers Kemp, Mahmoud Yousefifard, Aleksandra Barac, Simon I. Hay, Walter Mendoza, Mohammad Zamani, Nader Jafari Balalami, Mahdi Safdarian, Manfred S. Green, Mahesh P A, Nahid Neamati, Pallab K. Maulik, Ali H. Mokdad, Joshua Longbottom, Somayeh Bohlouli, Ahmad Daryani, Ibrahim Abdollahpour, Mostafa Hosseini, Deborah Carvalho Malta, Nick Golding, Sheikh Mohammed Shariful Islam, Shirin Nosratnejad, Haidong Wang, Shadi Rahimzadeh, Pushpendra Kumar, Mehdi Noroozi, Andre M. N. 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Singh, Yafeng Wang, Samath D Dharmaratne, Enrico Rubagotti, Ruxandra Irina Negoi, Reinhard Busse, Abdullah Al Mamun, Yoshan Moodley, Mohammed Almalki, Peter W. Gething, Alireza Khatony, Usman Iqbal, Soraya Nouraei Motlagh, Roy Burstein, Hamed Zandian, Rakhi Dandona, Mojtaba Bagherzadeh, Majid Pirestani, Jaifred Christian F. Lopez, Chuanhua Yu, Arash Ziapour, Seyed Sina Naghibi Irvani, Bárbara Niegia Garcia Goulart, Pascual R. Valdez, Amir Jalali, Chukwudi A Nnaji, Kelechi Elizabeth Oladimeji, Tomislav Mestrovic, Isidora S. Vujcic, Osayomwanbo Osarenotor, Azin Nahvijou, Chi Linh Hoang, Christopher J L Murray, Mustafa Z. Younis, Veincent Christian Filipino Pepito, Andre Rodrigues Duraes, Yuan-Pang Wang, Felix Akpojene Ogbo, Aniruddha Deshpande, Nicholas J Kassebaum, Jacek Jerzy Jozwiak, Soghra Bagheri, Paul S. F. Yip, Sree Bhushan Raju, Sadaf G. 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To, Ester Cerin, Martin Amogre Ayanore, Value, Affordability and Sustainability (VALUE), Real World Studies in PharmacoEpidemiology, -Genetics, -Economics and -Therapy (PEGET), Groningen Research Institute for Asthma and COPD (GRIAC), Veritati - Repositório Institucional da Universidade Católica Portuguesa, Department of Earth Observation Science, Faculty of Geo-Information Science and Earth Observation, UT-I-ITC-ACQUAL, GeoHealth, HUS Neurocenter, Department of Neurosciences, Neurologian yksikkö, Clinicum, HUS Comprehensive Cancer Center, Staff Services, Department of Surgery, University of Helsinki, Islam, Nazrul [0000-0003-3982-4325], Apollo - University of Cambridge Repository, Burstein R., Henry N.J., Collison M.L., Marczak L.B., Sligar A., Watson S., Marquez N., Abbasalizad-Farhangi M., Abbasi M., Abd-Allah F., Abdoli A., Abdollahi M., Abdollahpour I., Abdulkader R.S., Abrigo M.R.M., Acharya D., Adebayo O.M., Adekanmbi V., Adham D., Afshari M., Aghaali M., Ahmadi K., Ahmadi M., Ahmadpour E., Ahmed R., Akal C.G., Akinyemi J.O., Alahdab F., Alam N., Alamene G.M., Alene K.A., Alijanzadeh M., Alinia C., Alipour V., Aljunid S.M., Almalki M.J., Al-Mekhlafi H.M., Altirkawi K., Alvis-Guzman N., Amegah A.K., Amini S., Amit A.M.L., Anbari Z., Androudi S., Anjomshoa M., Ansari F., Antonio C.A.T., Arabloo J., Arefi Z., Aremu O., Armoon B., Arora A., Artaman A., Asadi A., Asadi-Aliabadi M., Ashraf-Ganjouei A., Assadi R., Ataeinia B., Atre S.R., Quintanilla B.P.A., Ayanore M.A., Azari S., Babaee E., Babazadeh A., Badawi A., Bagheri S., Bagherzadeh M., Baheiraei N., Balouchi A., Barac A., Bassat Q., Baune B.T., Bayati M., Bedi N., Beghi E., Behzadifar M., Belay Y.B., Bell B., Bell M.L., Berbada D.A., Bernstein R.S., Bhattacharjee N.V., Bhattarai S., Bhutta Z.A., Bijani A., Bohlouli S., Breitborde N.J.K., Britton G., Browne A.J., Nagaraja S.B., Busse R., Butt Z.A., Car J., Cardenas R., Castaneda-Orjuela C.A., Cerin E., Chanie W.F., Chatterjee P., Chu D.-T., Cooper C., Costa V.M., Dalal K., Dandona L., Dandona R., Daoud F., Daryani A., Das Gupta R., Davis I., Davis Weaver N., Davitoiu D.V., De Neve J.-W., Demeke F.M., Demoz G.T., Deribe K., Desai R., Deshpande A., Desyibelew H.D., Dey S., Dharmaratne S.D., Dhimal M., Diaz D., Doshmangir L., Duraes A.R., Dwyer-Lindgren L., Earl L., Ebrahimi R., Ebrahimpour S., Effiong A., Eftekhari A., Ehsani-Chimeh E., El Sayed I., El Sayed Zaki M., El Tantawi M., El-Khatib Z., Emamian M.H., Enany S., Eskandarieh S., Eyawo O., Ezalarab M., Faramarzi M., Fareed M., Faridnia R., Faro A., Fazaeli A.A., Fazlzadeh M., Fentahun N., Fereshtehnejad S.-M., Fernandes J.C., Filip I., Fischer F., Foigt N.A., Foroutan M., Francis J.M., Fukumoto T., Fullman N., Gallus S., Gebre D.G., Gebrehiwot T.T., Gebremeskel G.G., Gessner B.D., Geta B., Gething P.W., Ghadimi R., Ghadiri K., Ghajarzadeh M., Ghashghaee A., Gill P.S., Gill T.K., Golding N., Gomes N.G.M., Gona P.N., Gopalani S.V., Gorini G., Goulart B.N.G., Graetz N., Greaves F., Green M.S., Guo Y., Haj-Mirzaian A., Hall B.J., Hamidi S., Haririan H., Haro J.M., Hasankhani M., Hasanpoor E., Hasanzadeh A., Hassankhani H., Hassen H.Y., Hegazy M.I., Hendrie D., Heydarpour F., Hird T.R., Hoang C.L., Hollerich G., Rad E.H., Hoseini-Ghahfarokhi M., Hossain N., Hosseini M., Hosseinzadeh M., Hostiuc M., Hostiuc S., Househ M., Hsairi M., Ilesanmi O.S., Imani-Nasab M.H., Iqbal U., Irvani S.S.N., Islam N., Islam S.M.S., Jurisson M., Balalami N.J., Jalali A., Javidnia J., Jayatilleke A.U., Jenabi E., Ji J.S., Jobanputra Y.B., Johnson K., Jonas J.B., Shushtari Z.J., Jozwiak J.J., Kabir A., Kahsay A., Kalani H., Kalhor R., Karami M., Karki S., Kasaeian A., Kassebaum N.J., Keiyoro P.N., Kemp G.R., Khabiri R., Khader Y.S., Khafaie M.A., Khan E.A., Khan J., Khan M.S., Khang Y.-H., Khatab K., Khater A., Khater M.M., Khatony A., Khazaei M., Khazaei S., Khazaei-Pool M., Khubchandani J., Kianipour N., Kim Y.J., Kimokoti R.W., Kinyoki D.K., Kisa A., Kisa S., Kolola T., Kosen S., Koul P.A., Koyanagi A., Kraemer M.U.G., Krishan K., Krohn K.J., Kugbey N., Kumar G.A., Kumar M., Kumar P., Kuupiel D., Lacey B., Lad S.D., Lami F.H., Larsson A.O., Lee P.H., Leili M., Levine A.J., Li S., Lim L.-L., Listl S., Longbottom J., Lopez J.C.F., Lorkowski S., Magdeldin S., Abd El Razek H.M., Abd El Razek M.M., Majeed A., Maleki A., Malekzadeh R., Malta D.C., Mamun A.A., Manafi N., Manda A.-L., Mansourian M., Martins-Melo F.R., Masaka A., Massenburg B.B., Maulik P.K., Mayala B.K., Mazidi M., McKee M., Mehrotra R., Mehta K.M., Meles G.G., Mendoza W., Menezes R.G., Meretoja A., Meretoja T.J., Mestrovic T., Miller T.R., Miller-Petrie M.K., Mills E.J., Milne G.J., Mini G.K., Mir S.M., Mirjalali H., Mirrakhimov E.M., Mohamadi E., Mohammad D.K., Darwesh A.M., Mezerji N.M.G., Mohammed A.S., Mohammed S., Mokdad A.H., Molokhia M., Monasta L., Moodley Y., Moosazadeh M., Moradi G., Moradi M., Moradi Y., Moradi-Lakeh M., Moradinazar M., Moraga P., Morawska L., Mosapour A., Mousavi S.M., Mueller U.O., Muluneh A.G., Mustafa G., Nabavizadeh B., Naderi M., Nagarajan A.J., Nahvijou A., Najafi F., Nangia V., Ndwandwe D.E., Neamati N., Negoi I., Negoi R.I., Ngunjiri J.W., Thi Nguyen H.L., Nguyen L.H., Nguyen S.H., Nielsen K.R., Ningrum D.N.A., Nirayo Y.L., Nixon M.R., Nnaji C.A., Nojomi M., Noroozi M., Nosratnejad S., Noubiap J.J., Motlagh S.N., Ofori-Asenso R., Ogbo F.A., Oladimeji K.E., Olagunju A.T., Olfatifar M., Olum S., Olusanya B.O., Oluwasanu M.M., Onwujekwe O.E., Oren E., Ortega-Altamirano D.D.V., Ortiz A., Osarenotor O., Osei F.B., Osgood-Zimmerman A.E., Otstavnov S.S., Owolabi M.O., Mahesh P.A., Pagheh A.S., Pakhale S., Panda-Jonas S., Pandey A., Park E.-K., Parsian H., Pashaei T., Patel S.K., Pepito V.C.F., Pereira A., Perkins S., Pickering B.V., Pilgrim T., Pirestani M., Piroozi B., Pirsaheb M., Plana-Ripoll O., Pourjafar H., Puri P., Qorbani M., Quintana H., Rabiee M., Rabiee N., Radfar A., Rafiei A., Rahim F., Rahimi Z., Rahimi-Movaghar V., Rahimzadeh S., Rajati F., Raju S.B., Ramezankhani A., Ranabhat C.L., Rasella D., Rashedi V., Rawal L., Reiner Jr R.C., Renzaho A.M.N., Rezaei S., Rezapour A., Riahi S.M., Ribeiro A.I., Roever L., Roro E.M., Roser M., Roshandel G., Roshani D., Rostami A., Rubagotti E., Rubino S., Sabour S., Sadat N., Sadeghi E., Saeedi R., Safari Y., Safari-Faramani R., Safdarian M., Sahebkar A., Salahshoor M.R., Salam N., Salamati P., Salehi F., Zahabi S.S., Salimi Y., Salimzadeh H., Salomon J.A., Sambala E.Z., Samy A.M., Santric Milicevic M.M., Jose B.P.S., Saraswathy S.Y.I., Sarmiento-Suarez R., Sartorius B., Sathian B., Saxena S., Sbarra A.N., Schaeffer L.E., Schwebel D.C., Sepanlou S.G., Seyedmousavi S., Shaahmadi F., Shaikh M.A., Shams-Beyranvand M., Shamshirian A., Shamsizadeh M., Sharafi K., Sharif M., Sharif-Alhoseini M., Sharifi H., Sharma J., Sharma R., Sheikh A., Shields C., Shigematsu M., Shiri R., Shiue I., Shuval K., Siddiqi T.J., Silva J.P., Singh J.A., Sinha D.N., Sisay M.M., Sisay S., Sliwa K., Smith D.L., Somayaji R., Soofi M., Soriano J.B., Sreeramareddy C.T., Sudaryanto A., Sufiyan M.B., Sykes B.L., Sylaja P.N., Tabares-Seisdedos R., Tabb K.M., Tabuchi T., Taveira N., Temsah M.-H., Terkawi A.S., Tessema Z.T., Thankappan K.R., Thirunavukkarasu S., To Q.G., Tovani-Palone M.R., Tran B.X., Tran K.B., Ullah I., Usman M.S., Uthman O.A., Vahedian-Azimi A., Valdez P.R., van Boven J.F.M., Vasankari T.J., Vasseghian Y., Veisani Y., Venketasubramanian N., Violante F.S., Vladimirov S.K., Vlassov V., Vos T., Vu G.T., Vujcic I.S., Waheed Y., Wakefield J., Wang H., Wang Y., Wang Y.-P., Ward J.L., Weintraub R.G., Weldegwergs K.G., Weldesamuel G.T., Westerman R., Wiysonge C.S., Wondafrash D.Z., Woyczynski L., Wu A.-M., Xu G., Yadegar A., Yamada T., Yazdi-Feyzabadi V., Yilgwan C.S., Yip P., Yonemoto N., Lebni J.Y., Younis M.Z., Yousefifard M., Yousof H.-A.S.A., Yu C., Yusefzadeh H., Zabeh E., Moghadam T.Z., Bin Zaman S., Zamani M., Zandian H., Zangeneh A., Zerfu T.A., Zhang Y., Ziapour A., Zodpey S., Murray C.J.L., and Hay S.I.
Subjects: Survival, RJ101, Mortalidad Infantil, HB, UNDER-5 MORTALITY, Global Health, Pediatrics, 0302 clinical medicine, 3123 Gynaecology and paediatrics, Child death, Infant Mortality, Epidemiology, Global health, Middle income country, Nacimiento vivo, 030212 general & internal medicine, 10. No inequality, Child, POPULATION, Developing world, education.field_of_study, Public health, Multidisciplinary, Geography, Mortality rate, wa_900, 1. No poverty, SUCCESS, Pediatrik, A900 Others in Medicine and Dentistry, 3142 Public health care science, environmental and occupational health, 3. Good health, Child Mortality, Death children, VACCINATION, HEALTH, ws_100, INTERVENTIONS, AFRICA, medicine.medical_specialty, United Nations, General Science & Technology, 030231 tropical medicine, Population, Developing country, Article, Healthcare improvement science Radboud Institute for Health Sciences [Radboudumc 18], ITC-HYBRID, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, Social Justice, Recién nacido, Neonatal deaths, medicine, SYSTEMATIC ANALYSIS, Organizational Objectives, Humans, education, Developing Countries, business.industry, Infant, Newborn, Infant, CIVIL REGISTRATION, Paediatrics, Child survival, Newborn, PREVENTION, Infant mortality, wa_320, ws_200, Child mortality, Socioeconomic Factors, ITC-ISI-JOURNAL-ARTICLE, Human medicine, Paediatrics, Public health, Developing world, business, Demography
Abstract: Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2—to end preventable child deaths by 2030—we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000–2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations., A high-resolution, global atlas of mortality of children under five years of age between 2000 and 2017 highlights subnational geographical inequalities in the distribution, rates and absolute counts of child deaths by age.
Published: 2019

24. Echinococcus granulosus sheep strain (G1) as the predominant genotype in definitive host (dogs) isolates in northeastern Iran.

Author: Hejazi SH, Mirbadie SR, Jafari R, Rezaiemanesh MR, Azizi O, Badmasti F, Kalani H, Cheraghipour K, Heydarian P, Hashemi N, Izadi S, Jabalameli Z, and Mohaghegh MA
Subjects: Sheep, Dogs, Animals, Humans, Iran epidemiology, Genotype, Polymerase Chain Reaction veterinary, Echinococcus granulosus genetics, Echinococcosis epidemiology, Echinococcosis veterinary, Echinococcosis diagnosis, Dog Diseases parasitology, Sheep Diseases
Abstract: Echinococcus granulosus sensu lato (E. granulosus s.l.) is a zoonotic parasite, causing cystic echinococcosis in humans. In the present study, prevalence and genotypes of E. granulosus s.l. was assessed in stools collected from 244 dogs including 138 stray and 106 domestic animals using high resolution melting curve (HRM) method. Initially, to detect taeniid eggs in feces, all samples were examined using the formalin-ether techniques. Genomic DNA was extracted from the positive samples and E. granulosus s.l. was differentiated from other Taeniidae parasites using SSU-rDNA gene and E. granulosus s.l. was analyzed for genotyping using HRM based on the cox1 gene. In total, 12.7% (31/244) of the samples were positive for Taeniidae eggs. In addition, among the positive samples, 77.4% (24/31) were positive for E. granulosus s.l.. In details, 11.3% (12/106) of the domestic dogs and 8.7% (12/138) of the stray dogs were positive for E. granulosus s.l.. The results of HRM analysis showed that all E. granulosus s.l. isolates were G1 strain. Findings of the present study indicated a considerable prevalence of E. granulosus G1 among dogs in the northeast of Iran and imply a serious risk of transmitting to humans and livestock., Competing Interests: Declaration of Competing Interest The authors declare that they have no competing interests related to this research., (Copyright © 2023. Published by Elsevier B.V.)
Published: 2024
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25. In Vitro Anti-Leishmanial Activity of Glucosinolate Fraction from Alyssum linifolium Steph. ex Willd (Brassicaceae).

Author: Mirzaee F, Faridnia R, Fakhar M, Kalani H, and Shahani S
Abstract: Objectives: The intracellular parasitic protozoan, Leishmania spp., causes several forms of diseases in humans. Cytotoxicity and emergence of new strains resistance to the current anti-leishmanial drugs have encouraged researchers to focus on new resources. Glucosinolates (GSL) are found mainly in the Brassicaceae family with potential cytotoxic and anti-parasitic properties. The present study reports in vitro antileishmanial activity of the GSL fraction from Alyssum linifolium seeds against Leishmania major ., Materials and Methods: The GSL fraction was prepared by ion-exchange and reversed-phase chromatography. For the assessment of antileishmanial activity, the promastigotes and amastigotes of L. major were treated with different concentrations of the fraction (75-625 μg/mL)., Results: The IC 50 was 245 µg/mL for anti-promastigote effect of the GSL fraction and 250 µg/mL for its anti-amastigote effect that had a significant difference ( p <0.05) with both glucantime and amphotericin B. The selectivity index of the GSL fraction (15.8), to glucantime and amphotericin B, was greater than 10, indicating the selective effect of this fraction against L. major amastigotes. Glucoiberverin was the major constituent of the GSL fraction characterized using nuclear magnetic resonance and electron ionization-mass spectrometry spectra. Based on gas chromatography-mass spectrometry data, iberverin and iberverin nitrile, the hydrolysis constituents from glucoiberverin, included 76.91% of the total seed volatiles., Conclusion: The results suggest that GSLs like glucoiberverin could be considered a new promising candidate for further studies on antileishmanial activity., Competing Interests: Conflict of Interest: No conflict of interest was declared by the authors., (©Turk J Pharm Sci, Published by Galenos Publishing House.)
Published: 2023
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26. Third molar maturity index (I 3M ) assessment according to different geographical zones: a large multi-ethnic study sample.

Author: Angelakopoulos N, De Luca S, Oliveira-Santos I, Ribeiro ILA, Bianchi I, Balla SB, Kis HC, Jiménez LG, Zolotenkova G, Yusof MYP, Selmanagić AH, Pandey H, Pereira PC, da Nóbrega JBM, Kalani H, Mieke SM, Kumagai A, Gulsahi A, Zelić K, Marinković N, Kelmendi J, Galić I, Vázquez IS, Spinas E, Velezmoro-Montes YW, Moukarzel M, Toledo JP, El-Bakary AAE, and Cameriere R
Subjects: Adult, Humans, Male, Female, Adolescent, Europe, Asia, Radiography, Panoramic, Molar, Third diagnostic imaging, Age Determination by Teeth methods
Abstract: Identification of living undocumented individuals highlights the need for accurate, precise, and reproducible age estimation methods, especially in those cases involving minors. However, when their country of origin is unknown, or it can be only roughly estimated, it is extremely difficult to apply assessment policies, procedures, and practices that are accurate and child-sensitive. The main aim of this research is to optimize the correct classification of adults and minors by establishing new cut-off values for four different continents (Africa, America, Asia, and Europe). For this purpose, a vast sample of 10,701 orthopantomographs (OPTs) from four continents was evaluated. For determination and subsequent validation of the new third molar maturity index (I 3M ) cut-off values by world regions, a cross-validation by holdout method was used and contingency tables (confusion matrices) were generated. The lower third molar maturity indexes, from both left and right side (I 3M L and I 3M R) and the combination of both sides (I 3M L_I 3M R) were calculated. The new cut-off values, that aim to differentiate between a minor and an adult, with more than 74.00% accuracy for all populations were as follows (I 3M L; I 3M R; I 3M L_I 3M R, respectively): Africa = (0.10; 0.10; 0.10), America = (0.10; 0.09; 0.09), Asia = (0.15; 0.17; 0.14), and Europe = (0.09; 0.09; 0.09). The higher sensitivity (Se) was detected for the I 3M L for male African people (91%) and the higher specificity (Sp) of all the parameters (I 3M L; I 3M R; I 3M L_I 3M R) for Europeans both male and female (> 91%). The original cut-off value (0.08) is still useful, especially in discriminating individuals younger than 18 years old which is the goal of the forensic methods used for justice., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
Published: 2023
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27. Anti- Toxoplasma gondii Activity of Curcumin: A Systematic Review of Pre-clinical Studies.

Author: Kalani H, Shakib P, Faridnia R, Ho J, Mardanshah O, Dolatshah M, Sepahvand A, Cheraghipour K, and Zivdaria M
Subjects: Animals, Rats, Curcumin pharmacology, Curcumin therapeutic use, Toxoplasma
Abstract: Objective: This study has focused on anti-Toxoplasma gondii activity of curcumin., Methods: In this systematic review, anti-parasitic activity of Curcuma longa on Toxoplasma gondii was assessed. Therefore, several databases, including PubMed, Scopus, Web of Science, Embase and Google Scholar, were searched from 2010 to 2020., Results: Of the 2200 papers retrieved between 2010 and 2020, six articles were reliable and were scrutinized. In 2 in vitro studies, the most used strain was the RH strain of Toxoplasma gondii, whereas among 4 in vivo studies, RH strain was found in 2 (50%) studies, Me49 strain in 1(25%) study, and RH and Me49 strain in 1 (25%) study. In four in vivo studies, the most used animal model was BALB/c, and Swiss albino was found in 1 study (25%) and Albino rats in 1 study (25%)., Conclusion: Curcumin and nanoparticles formulated with curcumin are new and useful agents for the treatment of parasitic diseases and reduction of drug resistance. The success of this therapeutic approach stems from the specific action of Curcuma longa against parasites and pathogens., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
Published: 2023
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28. Prevalence of Toxoplasma gondii in HIV-Infected Individuals in Iran: A Systematic Review and Meta-Analysis.

Author: Shakib P, Behzadifar M, Mahmoudvand H, Larki S, Kalani H, Zivdari M, Mardanshah O, and Cheraghipour K
Subjects: Animals, Humans, Seroepidemiologic Studies, Iran epidemiology, Prevalence, Antibodies, Protozoan, Risk Factors, Toxoplasma, HIV Infections complications, HIV Infections epidemiology, Toxoplasmosis epidemiology, Acquired Immunodeficiency Syndrome
Abstract: Introduction: Toxoplasma gondii is an obligate intracellular protozoan that can infect almost all warm-blooded animals, including humans. Patients with co-infection with toxoplasmosis and HIV have a 30-40% risk of developing toxoplasmosis encephalitis. This study aimed to describe the epidemiology and burden of Toxoplasma gondii in HIV-infected individuals in Iran., Methods: We searched the five English databases (Science Direct, PubMed, Scopus, Ovid, Embase, and Cochrane) and four Persian databases (Scientific Information Database (SID), Iran Medex, Iran Doc, and Magiran) with the terms of (Toxoplasma gondii OR "toxoplasmosis") AND (HIV OR "AIDS" OR immunodeficiency OR acquired immune deficiency syndrome) AND (Seroprevalence) AND (Seroepidemiologic Studies) AND (Elisa OR IgG) AND (PCR) AND (Iran) by two authors up to Feb 2021. Studies were included if they investigated people with HIV infection and presented data that allowed us to establish the prevalence of Toxoplasma gondii infection in Iran., Results: According to the inclusion/exclusion criteria, 15 studies were selected. A total number of 2275 HIV-infected individuals were tested and evaluated for toxoplasmosis from 2005 up to 2018 in different regions of Iran. The weighted overall prevalence of toxoplasmosis in HIV-infected individuals with Elisa was obtained using a random-effects model, which was estimated at 47% (95% CI = 31% - 62%). Also, the Weighted overall prevalence of toxoplasmosis in HIV-infected individuals with PCR was obtained using a random-effects model, which was estimated at 7% (95% CI = 3% - 12%)., Conclusion: According to the results of this study, it can be clearly understood that a large population of HIV patients living in Iran have toxoplasmosis. Therefore, due to the high susceptibility of these groups to toxoplasmosis, healthcare professionals must consider measures such as training in the ways of transmission and prevention of the infection to this high-risk group in order to reduce the risk of infection., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
Published: 2023
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29. High Occurrence of Emerged Lophomonas Infection among Patients Suspected of Having Pulmonary Tuberculosis: In-House PCR-Based Evidence.

Author: Kalani H, Pangh A, Nakhaei M, Hezarjaribi HZ, Fakhar M, Sharifpour A, Banimostafavi ES, and Tabaripour R
Abstract: Objectives: Lophomonas infection is a respiratory disease in humans that is associated with symptoms of cough, sputum, dyspnea, and sometimes hemoptysis, which shows the importance of differentiating this disease from tuberculosis and asthma., Methods: This study was performed on 216 participants suspected of having tuberculosis who had symptoms of fever, chronic cough, or sputum and were referred to tuberculosis laboratories in three cities in Golestan Province, northeastern Iran, during 2019-2020. A sputum sample was taken from the suspected patients. DNA was extracted from the frozen samples, and an in-house polymerase chain reaction was performed to detect the Lophomonas DNA., Results: Out of 216 subjects, 47 (21.75%) were infected with Lophomonas spp. Moreover, 9 patients (4.2%) were infected with tuberculosis. Also, 2 patients had a comorbidity of tuberculosis and Lophomonas infection ( P =0.63). There was no significant difference in the comparison of symptoms and the rate of Lophomonas infection ( P =0.84), but in the comparison of the set of symptoms of cough, sputum, and fever with those of cough and sputum, cough with fever, sputum with fever, and the rate of Lophomonas infection, there was a significant difference ( P =0.012)., Conclusions: Lophomonas infection was relatively high in patients suspected of having tuberculosis and due to the similar clinical symptoms of Lophomonas infection and tuberculosis; it is recommended that the sputum samples of subjects suspected of having tuberculosis be examined for this parasite in order to make a correct diagnosis and the patients receive timely treatment and the appropriate medication., Competing Interests: The authors declare that they have no conflicts of interest., (Copyright © 2022 Hamed Kalani et al.)
Published: 2022
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30. New strategies in the treatment of diseases caused by Acanthamoeba based on nanoparticles: a systematic review.

Author: Shakib P, Kalani H, Tahir Aleem M, Faridnia R, Zebardast Pour M, Moradpour K, and Cheraghipour K
Abstract: Background: Acanthamoeba is one of the opportunistic parasites with a global prevalence. Currently, due to the side effects and the emergence of drug resistance to this parasite, much research has been performed on the use of nano-drugs to treat Acanthamoeba-caused diseases. Therefore, this systematic review study aims to evaluate new strategies for treating diseases caused by Acanthamoeba based on nanoparticles (NPs)., Methods: We designed a systematic review based on the articles published in English between 2000 and 2022. Our search strategy was based on syntax and specific tags for each database, including ScienceDirect, PubMed, Scopus, Ovid, and Cochrane. From the articles, those that had inclusion criteria were selected, and their data were extracted and analyzed., Results: In this study, 26 studies were selected. Metallic nanoparticles were mostly used against the Acanthamoeba species (80.7%). 19.2% of the studies used polymeric nanoparticles, and 3.8% used emulsion nanoparticles. Most studies (96.1%) were performed in vitro, and only one study (3.8%) was carried out in vivo. Silver NPs were the most used metallic nanoparticles in the studies. The best effect of the anti-Acanthamoeba compound was observed for green synthesized nanoparticles based on stabilization by plant gums, loaded with citrus fruits flavonoids hesperidin (HDN) and naringin (NRG) with a 100% growth inhibition at a concentration of 50 μg/mL., Conclusion: This study showed that chlorhexidine and other plant metabolites loaded with silver and gold nanoparticles increase the anti-Acanthambae activity of these nanoparticles. However, green synthesized nanoparticles based on stabilization by plant gums, loaded with citrus fruits flavonoids hesperidin (HDN) and naringin (NRG), showed the best anti-Acanthambae effect. Nevertheless, further studies should be performed to determine their safety for human use., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
Published: 2022
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31. Current challenges and nanotechnology-based pharmaceutical strategies for the treatment and control of malaria.

Author: Gujjari L, Kalani H, Pindiprolu SK, Arakareddy BP, and Yadagiri G
Abstract: Malaria is one of the prevalent tropical diseases caused by the parasitic protozoan of the genus Plasmodium spp. With an estimated 228 million cases, it is a major public health concern with high incidence of morbidity and mortality worldwide. The emergence of drug-resistant parasites, inadequate vector control measures, and the non-availability of effective vaccine(s) against malaria pose a serious challenge to malaria eradication especially in underdeveloped and developing countries. Malaria treatment and control comprehensively relies on chemical compounds, which encompass various complications, including severe toxic effects, emergence of drug resistance, and high cost of therapy. To overcome the clinical failures of anti-malarial chemotherapy, a new drug development is of an immediate need. However, the drug discovery and development process is expensive and time consuming. In such a scenario, nanotechnological strategies may offer promising alternative approach for the treatment and control of malaria, with improved efficacy and safety. Nanotechnology based formulations of existing anti-malarial chemotherapeutic agents prove to exceed the limitations of existing therapies in relation to optimum therapeutic benefits, safety, and cost effectiveness, which indeed advances the patient's compliance in treatment. In this review, the shortcomings of malaria therapeutics and necessity of nanotechnological strategies for treating malaria were discussed., Competing Interests: The authors declare no financial or commercial conflict of interest., (© 2022 Published by Elsevier Ltd on behalf of World Federation of Parasitologists.)
Published: 2022
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32. In Vivo and In Vitro Anti-schistosomiasis Effect of Garlic: A Systematic Review.

Author: Shakib P, Kalani H, Ali ASM, Zebardastpour M, Moradpour K, Ho J, Nazarabad VH, and Cheraghipour K
Subjects: Animals, Antioxidants pharmacology, Plant Extracts pharmacology, Schistosoma mansoni, Biological Products pharmacology, Garlic chemistry, Schistosomiasis drug therapy
Abstract: Background: Garlic (Allium sativum) is used as a natural supplement for the treatment of various diseases and disorders because it has antibacterial, antiviral, antifungal, antiparasitic, antioxidant, and anti-inflammatory properties. This systematic review aimed to evaluate in vitro and in vivo effects of garlic against Schistosoma spp., Methods: The current study was carried out according to the PRISMA guidelines and registered in the CAMARADES-NC3Rs Preclinical Systematic Review and Meta-analysis Facility [SyRF] database. The literature search was conducted using five databases, including Scopus, PubMed, Web of Science, Embase, and Google Scholar, from January 2008 to January 2021. The search was restricted to articles published in the English language. Syntax was performed based on each database tag., Results: Out of 2,600 studies, 10 met the eligibility criteria for review. The examined parasite in all studies was Schistosoma mansoni. Ten studies (90%) were performed in vivo and one study in vitro. Studies have shown that garlic compounds can activate immune system factors, thereby damaging the parasite structure or its eggs., Conclusion: Given the increase in using plants in the treatment of many diseases and the fact that plants can be a good alternative to chemical drugs in many cases, more comprehensive research is needed to introduce effective medicinal plants to treat diseases such as schistosomiasis., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
Published: 2022
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33. A Systematic Review on Curcumin and Anti-Plasmodium berghei Effects.

Author: Shakib P, Kalani H, Ho J, Dolatshah M, Amiri S, and Cheraghipour K
Subjects: Animals, Anti-Inflammatory Agents pharmacology, Mice, Plasmodium berghei, Antimalarials therapeutic use, Curcumin pharmacology, Curcumin therapeutic use, Malaria drug therapy
Abstract: Background: Turmeric (Curcuma longa L.) is a popular spice containing curcumin that is responsible for its therapeutic effects. Curcumin with anti-inflammatory, antioxidant, anti-cancer, and antimicrobial activities has led to a lot of research focusing on it over the years. This systematic review aimed to evaluate research on the anti-Plasmodium berghei activity of curcumin and its derivatives., Methods: Our study was performed according to PRISMA guidelines and was recorded in the database of a systematic review and preclinical meta-analysis of CAMARADESNC3Rs (SyRF). The search was performed in five databases, namely Scopus, PubMed, Web of Science, EMBASE, and Google Scholar, from 2010 to 2020. The following keywords were searched: "Plasmodium berghei", "Medicinal Plants", "Curcumin", "Concentration", Animals kind", "Treatment Durations", "Routes of Administration" and "in vivo"., Results: Of the 3,500 papers initially obtained, 14 articles were reliable and were thus scrutinized. Animal models were included in all studies. The most commonly used animal strain was Albino (43%), followed by C57BL/6 (22%). The other studies used various murine strains, including BALB/c (14%) and ICR (7%). Two (14%) studies did not mention the strain of animal model used. Curcumin alone or in combination with other compounds depending on the dose used, route of administration, and animal model showed a moderate to strong anti-Plasmodium berghei effect., Conclusion: According to the studies, curcumin has anti-malarial effects on Plasmodium berghei, and, however, its effect on human Plasmodium is unclear. Due to the side effects and drug resistance of current drugs in the treatment of human malaria, the use of new compounds with few or no side effects, such as curcumin, is recommended as an alternative or complementary treatment., (Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.)
Published: 2022
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34. First report of Lophomonas spp. in German cockroaches ( Blattella germanica ) trapped in hospitals, northern Iran.

Author: Motevalli-Haghi SF, Shemshadian A, Nakhaei M, Faridnia R, Dehghan O, Malekzadeh Shafaroudi M, Nejadi Kelarijani M, Nikookar SH, Kalani H, and Fakhar M
Abstract: Cockroaches are considered to be important reservoirs for protozoan and helminth parasites,particularly an emerging Lophomonas spp., protozoan parasite. German cockroaches, Blattella germanica ( B. germanica) , are domestic pest distributed worldwide. However, little information is available regarding the burden of Lophomonas spp. infestation among domestic cockroach population worldwide. The present study investigated parasitic agents, emphasizing Lophomonas spp. infestation among B. germanica in northern Iran. During spring and summer 2018, a total of 496 adults B. germanica (265 males and 231 females) were trapped by hand and glass traps from the teaching hospitals in Mazandaran, Sari, northern Iran. All cockroaches were identified using taxonomic keys. Each cockroaches was anesthetized with chloroform and the alimentary tract removed. Each section was smeared onto a glass slide. All the smears were examined under light microscopy to determine the presence of the parasites. Ten genera of parasites were identified from the trapped B. germanica ; overall, 233 (47%) were found to be positive for helminths (n = 135) and protozoa (n = 98). The helminths included Aspiculuris tetraptera egg (67/233, 28.7%), Oxiuros sp. (39/233; 16.7%), Dentostomella translucida (17/233; 7.3%), and nematodes Ova (12/233; 5.2%). The protozoan parasites identified Gregarina sp. (61/233; 26.2%), Entamoeba sp . (19/233; 8.2%), Blastocystis sp. (5/233; 2.1%), Lophomonas (4/233; 1.7%), Nyctotherus sp. (4/233; 1.7%) , unclassified flagella (5/233; 2.1%). Lophomonas spp. was detected within the gut of B. germanica , for the first time, in Iran. It has previously been identified in the gut of cockroaches a long time ago, however, this is the first attempt to detect Lophomonas in cockroaches housing in hospitals. Thereby, it possibly presenting pose a serious respiratory infection risk for patients and health care personnel., Competing Interests: Conflict of interestThe authors declare that they have no conflict of interest., (© Indian Society for Parasitology 2021.)
Published: 2021
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35. Morphological and Molecular Identification of Emerged Lophomonas blattarum Infection in Mazandaran Province, Northern Iran: First Registry-Based Study.

Author: Fakhar M, Nakhaei M, Sharifpour A, Safanavaei S, Abedi S, Tabaripour R, Aliyali M, Modanloo M, Saberi R, Kalani H, and Banimostafavi ES
Subjects: Adult, Aged, Humans, Iran epidemiology, Middle Aged, Nucleic Acid Amplification Techniques, Prevalence, Registries, Parabasalidea
Abstract: Background: In the last decade, several cases of bronchopulmonary lophomoniasis (BPL) have been recorded. Little information is available about epidemiological aspects on Lophomonas infection among BPL patients. The present study was aimed to investigate the prevalence of Lophomonas spp. infection in patients who were referred to the Iranian National Registry Center for Lophomoniasis (INRCL), using morphological and molecular tests., Subjects and Methods: We examined patients enrolled in the INRCL from 2017 to 2019 at the Mazandaran University of Medical Sciences, northern Iran. All bronchoalveolar lavage fluid (BALF) and two nasal discharges of the patients were examined by both microscopic and small-subunit ribosomal RNA (SSU rRNA) PCR methods. To confirm the species of Lophomonas, two positive samples were sequenced., Results: In this study, 321 specimens (including 319 BALF and 2 nasal discharges) were microscopically examined. Lophomonas spp. was found in 45(14%) (n = 44 BAL; n = 1 nasal discharge). The mean age of infected patients was 54.9 ± 17.1 years. The following morphological characteristics were observed in both fresh and Papanicolaou-stained smears to identify Lophomonas spp. All microscopically positive specimens were confirmed with genus-specific PCR technique. The obtained sequences were deposited in Gen Bank under the accession numbers (MN243135-36). The BLAST analysis of our two sequences with the only available sequence in the Gen Bank of the Thailand strain of L. blattarum, showed identity of 99-100% and 98.51%, respectively., Conclusion: To the best of our knowledge, this is the first registry-based study regarding lophomoniasis worldwide. According to our study, the conventional PCR test is an available and reliable tool for confirming the Lophomonas parasite in clinical samples. Moreover, the results confirmed that L. blattarum is circulating at least in our region., (© 2021. Witold Stefański Institute of Parasitology, Polish Academy of Sciences.)
Published: 2021
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36. Comparative evaluation of amniotic fluid as an alternative to fetal bovine serum in the maintenance of Leishmania major and Toxoplasma gondii.

Author: Rahmani Z, Faridnia R, Kalani H, Ghanei N, Fakhar M, Zamanian M, Keighobadi M, and Tabaripour R
Subjects: Analysis of Variance, Animals, Cesarean Section, Culture Media, Female, Pregnancy, Temperature, Amniotic Fluid parasitology, Leishmania major growth & development, Serum Albumin, Bovine, Toxoplasma growth & development
Abstract: This study aimed to evaluate the efficacy of amniotic fluid (AF) as an alternative to fetal bovine serum (FBS) in the maintenance of Leishmania major promastigotes and Toxoplasma gondii tachyzoites. AF was collected by an obstetrician using sterile syringes during a cesarean section. The culture medium was supplemented with 5 different concentrations of FBS or AF including 2, 5, 10, 20, and 30%. These concentrations were used to maintain both mentioned parasites. L. major was maintained at temperatures 4 and 24 °C and examined once a week for 4 weeks, while T. gondii was maintained at temperatures 4, 24, and 37 °C and examined at hours 24, 48, 72, and 96. For L. major, at both 4 and 24 °C, we observed no significant difference between FBS and AF on day 7. However, on days 14, 21, and 28, the difference between FBS and AF was significant at both temperatures. For T. gondii, no significant difference was observed between FBS and AF at hour 24 and all temperatures. However, this difference was significant at hours 48, 72, and 96 and all temperatures. According to our results, although FBS had a greater efficacy than AF in the growth of L. major and the survival of T. gondii, the number of promastigotes increased over time in AF-containing medium and the number of tachyzoites reduced slowly with a mild slop. Therefore, AF can be a potential alternative to FBS.
Published: 2021
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37. Seroprevalence of toxoplasmosis in Kermanshah City, west of Iran.

Author: Kalani H, Mohammadi F, Faridnia R, Mirzaei F, Virgilio S, Heydarian P, Naghipourborj F, Badiee SE, Bakhtiari M, and Mohaghegh MA
Subjects: Antibodies, Protozoan, Cross-Sectional Studies, Female, Humans, Iran epidemiology, Male, Pregnancy, Retrospective Studies, Risk Factors, Seroepidemiologic Studies, Toxoplasma, Toxoplasmosis epidemiology
Abstract: It is estimated that one-third of the world's population is infected with Toxoplasma gondii. The purpose of this study was to evaluate the latest status of toxoplasmosis seroprevalence in the general population and pregnant women in the west of Iran. This retrospective cross-sectional study was conducted in 2018. Accordingly, data associated with serodiagnosis of toxoplasmosis, age, sex, anti-toxoplasmosis IgG and IgM, and pregnancy status in women were collected from 6 health centers of Kermanshah City, the west of Iran, during 2016-2017. In total, 1228 people referred to the health centers in Kermanshah City. Of 1228 people, 359 (29.23%) individuals were seropositive for toxoplasmosis, of them 294 (81.89%) individuals were seropositive only for IgG, and 65 (18.11%) individuals were both IgG and IgM seropositive. The seropositivity in men was 29.3% (n = 63), in women was 29.2% (n = 296), and in pregnant women was 25.9% (n = 44). All individuals were examined using ELISA kit. This study showed that the prevalence of this disease in the west of Iran has been decreased in comparison with the previous studies. Therefore, regular epidemiological studies of in different regions seem to be necessary in order to conclude on the decrease or increase trend of this disease in an area.
Published: 2021
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38. Peganum harmala and Nigella sativa: anti-leishmanial activity against Leishmania major promastigotes and amastigotes: in vitro and ex vivo experiment.

Author: Rokni N, Faridnia R, Esboei BR, Eslami S, Fakhar M, Youssefi MR, Kalani H, and Keighobadi M
Subjects: Macrophages, Antiprotozoal Agents pharmacology, Antiprotozoal Agents therapeutic use, Leishmania major, Nigella sativa, Peganum
Abstract: Leishmaniosis is one of the most important vectors borne disease that is endemic in tropical and subtropical areas. There are many approved treatment for different types of leishmaniosis but all are with some adverse side effects that limited its uses. Here, we attempt to evaluate in vitro and ex vivo anti-leishmanial activities of Peganum harmala (P. harmala) and N. sativa (Nigella sativa) on promastigotes and amastigotes of L. major. The plants were extracted by maceration method and prepared in concentrations of 7.8, 3.9, 1.9, and 0.9 μg. L. major were cultured in RPMI-1640 medium alone and in J774 cell line separately. The extracts at different concentrations were assessed against promastigote (in vitro assay) and amastigotes (ex vivo assay) of L. major for 72 h at 22 and 37°C, respectively. In current work, N. sativa at highest concentration (7.8 μg/ml) showed 54.4 and 60% anti-leishmanial activity with IC50 of 5.3 and 3.278 μg/ml, respectively. Also, P. harmala at highest concentration (7.8 μg/ml) showed 68.9 and 58.6% antileishmanial activity with IC50 of 2.4 μg/ml for both of them, respectively. The SI value was 38.22 for N. sativa, 25.9 for P. harmala, 19.4 for Amphotericin B, and 16.33 for Glucantime. The results of our study indicated that N. sativa and P. harmala are effective against L. major promastigotes and amastigotes and could be consider as an alternative treatments for leishmaniosis. Therefore, it is recommended that further studies be performed to confirm the efficacy and evaluate the toxicity of the herbal extracts.
Published: 2021
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39. Actin Gene-Based Molecular Typing of Trichomonas vaginalis Clinical Isolates from the North of Iran.

Author: Ziaei Hezarjaribi H, Taghavi M, Hasanjani Saravi K, Faridnia R, Kalani H, Mardani A, Jorjani O, Hosseinikhah Z, Rahimi Esboei B, Gholami M, and Fakhar M
Subjects: Actins genetics, Female, Humans, Iran epidemiology, Male, Molecular Typing, Phylogeny, Trichomonas Infections epidemiology, Trichomonas vaginalis genetics
Abstract: Aim: The aim of the current study is to evaluate the prevalence of trichomoniasis in men and women in the north of Iran and to find genotypes in the positive clinical specimens based on T. vaginalis actin gene., Materials and Methods: Women's genital (n = 500) and men's urine (n = 1500) samples were collected from the participants referred to clinics in Mazandaran Province, northern Iran, during 2006-2018. In addition, 1500 Pap smear specimens, archived in the Bu Ali Hospital, Sari City, Mazandaran Province, northern Iran, were examined. The specimens were examined based on parasitological methods, nested polymerase chain reaction (PCR), PCR-restriction fragment length polymorphism, and phylogenetic analysis., Results: Overall, 17 (0.48%) of 3500 specimens were positive by PCR. Total prevalence was 0.55% (n = 2000) for women, of which 500 (1.4%; n = 7) specimens were collected freshly, and 1500 (0.26%; n = 4) were Pap smears. Moreover, six (0.4%) out of 1500 men urine specimens were positive. Overall, genotypes G, E, and I were detected with the prevalence of seven (0.2%), seven (0.2%), and three (0.08%), respectively. There was no significant statistical difference among the prevalence of the detected genotypes (P > 0.05)., Conclusion: As a whole, the prevalence of trichomoniasis was low in the studied area in the north of Iran and, most importantly, the genotypes of E, G, and I were distributed among men and women in the province.
Published: 2020
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40. Apoptotic blebs from Leishmania major-infected macrophages as a new approach for cutaneous leishmaniasis vaccination.

Author: Faridnia R, Kalani H, Hezarjaribi HZ, Denny PW, Rafie A, Fakhar M, and Virgilio S
Subjects: Animals, Mice, Antigens, Protozoan, Cytokines, Macrophages, Mice, Inbred BALB C, Leishmania major pathogenicity, Leishmaniasis, Leishmaniasis, Cutaneous prevention & control, Vaccination
Abstract: We focused on apoptotic blebs from Leishmania major-infected macrophages as a vaccine for cutaneous leishmaniasis. Apoptosis was induced in L. major-infected J774A.1 cells in order to prepare apoptotic blebs. Test groups of BALB/c mice were immunized with these at doses of 1 × 10 6 , 5 × 10 6 or 1 × 10 7 blebs. An immunization control group received Leishmania lysate antigens. The results showed that as the number of apoptotic bodies increased, the lymphocyte proliferation index increased, and this was proportional to IFN-γ level in the test groups. Additionally, the difference of IFN-γ, IL-4, IFN-γ/IL-4 ratio, or total IgG (p < 0.0001) in all groups was statistically significant compared to the negative control group. The highest IFN-γ (514.0 ± 40.92 pg/mL) and IFN-γ/IL-4 ratio (2.94 ± 0.22) were observed in the group that received 1 × 10 7 apoptotic blebs. The highest levels of IL-4 (244.6 ± 38.8 pg/mL) and total IgG (5626 ± 377 μg/mL) were observed in the immunization control group. Reflecting these data, no lesions were observed in any of the groups vaccinated with apoptotic blebs after 12 weeks. In summary, the use of apoptotic blebs from L. major-infected macrophages is protective against the challenge with L. major in this animal model., (Copyright © 2020 Elsevier Ltd. All rights reserved.)
Published: 2020
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41. A new effective antiplasmodial compound: Nanoformulated pyrimethamine.

Author: Pestehchian N, Vafaei MR, Nematolahy P, Varshosaz J, Yousefi HA, Bide VZ, and Kalani H
Subjects: Animals, Antimalarials chemical synthesis, Antimalarials chemistry, Antimalarials pharmacology, Disease Models, Animal, Drug Compounding, Liver drug effects, Liver parasitology, Male, Mice, Micelles, Nanoparticles, Particle Size, Plasmodium berghei pathogenicity, Pyrimethamine chemical synthesis, Pyrimethamine chemistry, Pyrimethamine pharmacology, Random Allocation, Spleen drug effects, Spleen parasitology, Survival Analysis, Treatment Outcome, Antimalarials administration & dosage, Malaria drug therapy, Parasitemia drug therapy, Plasmodium berghei drug effects, Poloxamer chemistry, Pyrimethamine administration & dosage
Abstract: Objectives: The aim of this study was to evaluate the efficacy of pyrimethamine-loaded poloxamer 407 nanomicelles on Plasmodium berghei strain NICD in vivo., Methods: Pyrimethamine-loaded nanomicelles were prepared and their zeta potential, particle size and polydispersity index were measured. For antiplasmodial assessment, 54 mice were randomly divided into six groups. Four groups were infected intraperitoneally with P. berghei, whereas the two remaining groups did not receive the parasite (negative controls). Three of the P. berghei-infected groups received treatment with either pyrimethamine-loaded nanomicelles (2 mg/kg), pyrimethamine (2 mg/kg) or empty nanomicelles (2 mg/kg); the fourth group remained untreated (positive control). The parasitaemia rate, survival rate and histopathological changes in the liver, spleen and kidneys were examined and were compared with the negative and positive control groups., Results: The mean parasitaemia rate differed significantly between the nanoformulated pyrimethamine group and each of the other groups (P<0.05). Moreover, the survival rate of mice in the nanoformulated pyrimethamine group (7/9; 78%) was significantly higher compared with each of the other groups (P<0.01). The main histopathological changes, including hepatic necrosis in the liver, lymphoid hypoplasia in the spleen, and tubular nephrosis and perivascular and interstitial lymphocytic infiltration in the kidneys, were considerably lower in the nanoformulated pyrimethamine group than in the pyrimethamine and positive control groups., Conclusion: Pyrimethamine-loaded nanomicelles showed potent antimalarial activity and can be considered as a potential candidate for further examination of their suitability as an antimalarial drug., (Copyright © 2019 International Society for Antimicrobial Chemotherapy. Published by Elsevier Ltd. All rights reserved.)
Published: 2020
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42. Status of fasciolosis among domestic ruminants in Iran based on abattoir data: a systematic review and meta-analysis

Author: Soosaraei M, Fakhar M, Teshnizi SH, Emameh RZ, Hezarjaribi HZ, Asfaram S, Faridnia R, and Kalani H
Subjects: Animals, Cattle, Goats, Iran epidemiology, Prevalence, Ruminants parasitology, Sheep, Abattoirs statistics & numerical data, Cattle Diseases epidemiology, Fasciola, Fascioliasis epidemiology, Fascioliasis veterinary, Sheep Diseases epidemiology
Abstract: Fasciolosis is considered as an ongoing neglected zoonotic disease in tropical regions of the world, relating to notable financial and public health issues. The current systematic review and meta-analysis was planned to determine the status of fasciolosis among domestic ruminants, including cattle, buffalo, goat, and sheep at the industrial slaughterhouses in Iran, between the years 2000 and 2016. Eight databases, four English and four Persian, were searched. Our findings demonstrated that 2.6% of all inspected livers of slaughtered ruminants were infected with Fasciola spp. during 2000–2016. The mean prevalence of fasciolosis for cattle, buffalo, goat, and sheep was 21%, 4.2%, 2%, and 2.4%, respectively. Additionally, most studies were performed on cattle 25 (39.6%), sheep 24 (38 %), and goat 12 (19%), respectively, and just 2 (3.1%) studies were performed on buffalo. The prevalence of animal fasciolosis has significantly decreased among domestic ruminants in Iran except for cattle. In addition, the prevalence of this disease in Northern and Western regions of the country has remained at hypo-endemic level. The results present updated gathered information on the epidemiology of fasciolosis in domestic ruminants in Iran, and will expand the screening strategies to improve health and reduce economic impacts among farm animals.
Published: 2020
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43. Antileishmanial and antibacterial activities of the hydroalcoholic extract of Rhus coriaria L.

Author: Ashoori F, Fakhar M, Goli HR, Mirzaee F, Faridnia R, Kalani H, and Shahani S
Subjects: Fruit chemistry, Gram-Negative Bacteria drug effects, Gram-Positive Bacteria drug effects, Leishmania major drug effects, Anti-Bacterial Agents pharmacology, Antiprotozoal Agents pharmacology, Plant Extracts pharmacology, Rhus chemistry
Abstract: Leishmaniosis is one of the most serious public health concern with a worldwide distribution. Since the current treatments of leishmaniosis are toxic and expensive, frequent studies have been conducted to investigate the benefits of new resources such as medicinal plants for treatment of this infectious disease. Recent studies revealed the antiparasitic potential of Rhus coriaria. Here we investigated the potential antileishmanial and antibacterial activities of the hydroalcoholic extract of R. coriaria fruits. The fruits were extracted using 80% methanol by maceration method. The concentrations of 312, 156, 78, and 37 μg/ml of the extract were added separately to the wells containing Leishmania major (L. major) promastigotes and amastigotes. Amphotericin B was considered as positive control. Finally, the death rate was determined for the extract-treated parasites as compared to the non-treated parasite. The antibacterial activity was evaluated by measurement of the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of the extract against a set of Gram-positive and Gram-negative bacteria. The extract significantly inhibited the growth of both promastigotes (60,7%) and amastigotes (59%) at the concentration of 312 μg/ml with the IC50 values of 147 μg/ml and 233 μg/ml, respectively. The extract showed bactericidal effects against Staphylococcus aureus, Enterococcus faecalis, Pseudomonas aeruginosa, and Acinetobacter baumannii. Totally, Grampositive bacteria were more susceptible to the extract. Our findings show that the hydroalcoholic extract of R. coriaria fruits are rich in tannins and can be considered for further in vivo studies on the antileishmanial and antibacterial activities especially on dermal lesions caused by L. major.
Published: 2020
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44. Mapping 123 million neonatal, infant and child deaths between 2000 and 2017.

Author: Burstein R, Henry NJ, Collison ML, Marczak LB, Sligar A, Watson S, Marquez N, Abbasalizad-Farhangi M, Abbasi M, Abd-Allah F, Abdoli A, Abdollahi M, Abdollahpour I, Abdulkader RS, Abrigo MRM, Acharya D, Adebayo OM, Adekanmbi V, Adham D, Afshari M, Aghaali M, Ahmadi K, Ahmadi M, Ahmadpour E, Ahmed R, Akal CG, Akinyemi JO, Alahdab F, Alam N, Alamene GM, Alene KA, Alijanzadeh M, Alinia C, Alipour V, Aljunid SM, Almalki MJ, Al-Mekhlafi HM, Altirkawi K, Alvis-Guzman N, Amegah AK, Amini S, Amit AML, Anbari Z, Androudi S, Anjomshoa M, Ansari F, Antonio CAT, Arabloo J, Arefi Z, Aremu O, Armoon B, Arora A, Artaman A, Asadi A, Asadi-Aliabadi M, Ashraf-Ganjouei A, Assadi R, Ataeinia B, Atre SR, Quintanilla BPA, Ayanore MA, Azari S, Babaee E, Babazadeh A, Badawi A, Bagheri S, Bagherzadeh M, Baheiraei N, Balouchi A, Barac A, Bassat Q, Baune BT, Bayati M, Bedi N, Beghi E, Behzadifar M, Behzadifar M, Belay YB, Bell B, Bell ML, Berbada DA, Bernstein RS, Bhattacharjee NV, Bhattarai S, Bhutta ZA, Bijani A, Bohlouli S, Breitborde NJK, Britton G, Browne AJ, Nagaraja SB, Busse R, Butt ZA, Car J, Cárdenas R, Castañeda-Orjuela CA, Cerin E, Chanie WF, Chatterjee P, Chu DT, Cooper C, Costa VM, Dalal K, Dandona L, Dandona R, Daoud F, Daryani A, Das Gupta R, Davis I, Davis Weaver N, Davitoiu DV, De Neve JW, Demeke FM, Demoz GT, Deribe K, Desai R, Deshpande A, Desyibelew HD, Dey S, Dharmaratne SD, Dhimal M, Diaz D, Doshmangir L, Duraes AR, Dwyer-Lindgren L, Earl L, Ebrahimi R, Ebrahimpour S, Effiong A, Eftekhari A, Ehsani-Chimeh E, El Sayed I, El Sayed Zaki M, El Tantawi M, El-Khatib Z, Emamian MH, Enany S, Eskandarieh S, Eyawo O, Ezalarab M, Faramarzi M, Fareed M, Faridnia R, Faro A, Fazaeli AA, Fazlzadeh M, Fentahun N, Fereshtehnejad SM, Fernandes JC, Filip I, Fischer F, Foigt NA, Foroutan M, Francis JM, Fukumoto T, Fullman N, Gallus S, Gebre DG, Gebrehiwot TT, Gebremeskel GG, Gessner BD, Geta B, Gething PW, Ghadimi R, Ghadiri K, Ghajarzadeh M, Ghashghaee A, Gill PS, Gill TK, Golding N, Gomes NGM, Gona PN, Gopalani SV, Gorini G, Goulart BNG, Graetz N, Greaves F, Green MS, Guo Y, Haj-Mirzaian A, Haj-Mirzaian A, Hall BJ, Hamidi S, Haririan H, Haro JM, Hasankhani M, Hasanpoor E, Hasanzadeh A, Hassankhani H, Hassen HY, Hegazy MI, Hendrie D, Heydarpour F, Hird TR, Hoang CL, Hollerich G, Rad EH, Hoseini-Ghahfarokhi M, Hossain N, Hosseini M, Hosseinzadeh M, Hostiuc M, Hostiuc S, Househ M, Hsairi M, Ilesanmi OS, Imani-Nasab MH, Iqbal U, Irvani SSN, Islam N, Islam SMS, Jürisson M, Balalami NJ, Jalali A, Javidnia J, Jayatilleke AU, Jenabi E, Ji JS, Jobanputra YB, Johnson K, Jonas JB, Shushtari ZJ, Jozwiak JJ, Kabir A, Kahsay A, Kalani H, Kalhor R, Karami M, Karki S, Kasaeian A, Kassebaum NJ, Keiyoro PN, Kemp GR, Khabiri R, Khader YS, Khafaie MA, Khan EA, Khan J, Khan MS, Khang YH, Khatab K, Khater A, Khater MM, Khatony A, Khazaei M, Khazaei S, Khazaei-Pool M, Khubchandani J, Kianipour N, Kim YJ, Kimokoti RW, Kinyoki DK, Kisa A, Kisa S, Kolola T, Kosen S, Koul PA, Koyanagi A, Kraemer MUG, Krishan K, Krohn KJ, Kugbey N, Kumar GA, Kumar M, Kumar P, Kuupiel D, Lacey B, Lad SD, Lami FH, Larsson AO, Lee PH, Leili M, Levine AJ, Li S, Lim LL, Listl S, Longbottom J, Lopez JCF, Lorkowski S, Magdeldin S, Abd El Razek HM, Abd El Razek MM, Majeed A, Maleki A, Malekzadeh R, Malta DC, Mamun AA, Manafi N, Manda AL, Mansourian M, Martins-Melo FR, Masaka A, Massenburg BB, Maulik PK, Mayala BK, Mazidi M, McKee M, Mehrotra R, Mehta KM, Meles GG, Mendoza W, Menezes RG, Meretoja A, Meretoja TJ, Mestrovic T, Miller TR, Miller-Petrie MK, Mills EJ, Milne GJ, Mini GK, Mir SM, Mirjalali H, Mirrakhimov EM, Mohamadi E, Mohammad DK, Darwesh AM, Mezerji NMG, Mohammed AS, Mohammed S, Mokdad AH, Molokhia M, Monasta L, Moodley Y, Moosazadeh M, Moradi G, Moradi M, Moradi Y, Moradi-Lakeh M, Moradinazar M, Moraga P, Morawska L, Mosapour A, Mousavi SM, Mueller UO, Muluneh AG, Mustafa G, Nabavizadeh B, Naderi M, Nagarajan AJ, Nahvijou A, Najafi F, Nangia V, Ndwandwe DE, Neamati N, Negoi I, Negoi RI, Ngunjiri JW, Thi Nguyen HL, Nguyen LH, Nguyen SH, Nielsen KR, Ningrum DNA, Nirayo YL, Nixon MR, Nnaji CA, Nojomi M, Noroozi M, Nosratnejad S, Noubiap JJ, Motlagh SN, Ofori-Asenso R, Ogbo FA, Oladimeji KE, Olagunju AT, Olfatifar M, Olum S, Olusanya BO, Oluwasanu MM, Onwujekwe OE, Oren E, Ortega-Altamirano DDV, Ortiz A, Osarenotor O, Osei FB, Osgood-Zimmerman AE, Otstavnov SS, Owolabi MO, P A M, Pagheh AS, Pakhale S, Panda-Jonas S, Pandey A, Park EK, Parsian H, Pashaei T, Patel SK, Pepito VCF, Pereira A, Perkins S, Pickering BV, Pilgrim T, Pirestani M, Piroozi B, Pirsaheb M, Plana-Ripoll O, Pourjafar H, Puri P, Qorbani M, Quintana H, Rabiee M, Rabiee N, Radfar A, Rafiei A, Rahim F, Rahimi Z, Rahimi-Movaghar V, Rahimzadeh S, Rajati F, Raju SB, Ramezankhani A, Ranabhat CL, Rasella D, Rashedi V, Rawal L, Reiner RC Jr, Renzaho AMN, Rezaei S, Rezapour A, Riahi SM, Ribeiro AI, Roever L, Roro EM, Roser M, Roshandel G, Roshani D, Rostami A, Rubagotti E, Rubino S, Sabour S, Sadat N, Sadeghi E, Saeedi R, Safari Y, Safari-Faramani R, Safdarian M, Sahebkar A, Salahshoor MR, Salam N, Salamati P, Salehi F, Zahabi SS, Salimi Y, Salimzadeh H, Salomon JA, Sambala EZ, Samy AM, Santric Milicevic MM, Jose BPS, Saraswathy SYI, Sarmiento-Suárez R, Sartorius B, Sathian B, Saxena S, Sbarra AN, Schaeffer LE, Schwebel DC, Sepanlou SG, Seyedmousavi S, Shaahmadi F, Shaikh MA, Shams-Beyranvand M, Shamshirian A, Shamsizadeh M, Sharafi K, Sharif M, Sharif-Alhoseini M, Sharifi H, Sharma J, Sharma R, Sheikh A, Shields C, Shigematsu M, Shiri R, Shiue I, Shuval K, Siddiqi TJ, Silva JP, Singh JA, Sinha DN, Sisay MM, Sisay S, Sliwa K, Smith DL, Somayaji R, Soofi M, Soriano JB, Sreeramareddy CT, Sudaryanto A, Sufiyan MB, Sykes BL, Sylaja PN, Tabarés-Seisdedos R, Tabb KM, Tabuchi T, Taveira N, Temsah MH, Terkawi AS, Tessema ZT, Thankappan KR, Thirunavukkarasu S, To QG, Tovani-Palone MR, Tran BX, Tran KB, Ullah I, Usman MS, Uthman OA, Vahedian-Azimi A, Valdez PR, van Boven JFM, Vasankari TJ, Vasseghian Y, Veisani Y, Venketasubramanian N, Violante FS, Vladimirov SK, Vlassov V, Vos T, Vu GT, Vujcic IS, Waheed Y, Wakefield J, Wang H, Wang Y, Wang YP, Ward JL, Weintraub RG, Weldegwergs KG, Weldesamuel GT, Westerman R, Wiysonge CS, Wondafrash DZ, Woyczynski L, Wu AM, Xu G, Yadegar A, Yamada T, Yazdi-Feyzabadi V, Yilgwan CS, Yip P, Yonemoto N, Lebni JY, Younis MZ, Yousefifard M, Yousof HSA, Yu C, Yusefzadeh H, Zabeh E, Moghadam TZ, Bin Zaman S, Zamani M, Zandian H, Zangeneh A, Zerfu TA, Zhang Y, Ziapour A, Zodpey S, Murray CJL, and Hay SI
Subjects: Child, Geography, Global Health, Humans, Infant, Infant, Newborn, Organizational Objectives, Public Health, Socioeconomic Factors, United Nations, Child Mortality trends, Infant Mortality trends
Abstract: Since 2000, many countries have achieved considerable success in improving child survival, but localized progress remains unclear. To inform efforts towards United Nations Sustainable Development Goal 3.2-to end preventable child deaths by 2030-we need consistently estimated data at the subnational level regarding child mortality rates and trends. Here we quantified, for the period 2000-2017, the subnational variation in mortality rates and number of deaths of neonates, infants and children under 5 years of age within 99 low- and middle-income countries using a geostatistical survival model. We estimated that 32% of children under 5 in these countries lived in districts that had attained rates of 25 or fewer child deaths per 1,000 live births by 2017, and that 58% of child deaths between 2000 and 2017 in these countries could have been averted in the absence of geographical inequality. This study enables the identification of high-mortality clusters, patterns of progress and geographical inequalities to inform appropriate investments and implementations that will help to improve the health of all populations.
Published: 2019
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45. First Molecular Diagnosis of Lophomoniasis: the End of a Controversial Story.

Author: Fakhar M, Nakhaei M, Sharifpour A, Kalani H, Banimostafavi ES, Abedi S, Safanavaei S, and Aliyali M
Subjects: Adult, Antiprotozoal Agents therapeutic use, Female, Humans, Immunocompetence, Iran, Lung Diseases, Parasitic parasitology, Metronidazole therapeutic use, Molecular Diagnostic Techniques, Parabasalidea genetics, Sinusitis parasitology, Lung Diseases, Parasitic diagnosis, Parabasalidea isolation & purification
Abstract: Introduction: We report a case of lophomoniasis in an immunocompetent patient with acute paranasal sinusitis from the north of Iran whose disease was diagnosed by both microscopic and molecular methods., Case Presentation: The patient, a 40-year-old woman, suffered from upper respiratory infection, was referred to the Iranian National Registry Center for Lophomoniasis (INRCL) at the Mazandaran University of Medical Sciences, Sari, Iran, for diagnosis. A direct wet mount of nasal discharge revealed the flagellate protozoa morphologically identified Lophomonas blattarum. Moreover, through a specific polymerase chain reaction (PCR) of nasal discharge, a 214-bp band was observed, confirming the genus Lophomonas spp. The patient was treated successfully with metronidazole 500 mg t.i.d for 1 week., Conclusion: To the best of our knowledge, this is the first molecular detection of lophomoniasis in the literature. According to our preliminary study, a reliable PCR test is available now for detecting the Lophomonas parasite.
Published: 2019
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46. Human urogenital myiasis: A systematic review of reported cases from 1975 to 2017.

Author: Faridnia R, Soosaraei M, Kalani H, Fakhar M, Jokelainen P, Zolfaghari Emameh R, Banimostafavi ES, and Ziaei Hezarjaribi H
Subjects: Adolescent, Adult, Aged, Aged, 80 and over, Animals, Brazil, Child, Child, Preschool, Female, Female Urogenital Diseases parasitology, Humans, Incidence, Male, Male Urogenital Diseases parasitology, Middle Aged, Myiasis parasitology, Prevalence, Psychodidae, Young Adult, Diptera, Female Urogenital Diseases epidemiology, Larva, Male Urogenital Diseases epidemiology, Myiasis epidemiology
Abstract: The public health importance of myiasis [infestation with dipterous (fly) larvae] remains unknown. This disease is spread worldwide in animals and humans, but baseline data on its prevalence are limited. In particular, knowledge on human urogenital myiasis (UGM) is scattered. As such, a systematic search was undertaken of five English and five Persian databases for publications describing UGM cases in English or Persian published between 1975 and 2017. In total, 45 papers reporting 59 UGM cases from various regions of the world are included in this review. All included papers were from the English databases. The age of patients ranged from 5 to 89 years, and the mean age was 40.6 years. Thirty-six of the patients were female and 19 were male. The highest number of cases (n = 12) was reported from Brazil. The most common genera causing UGM were Psychoda spp. (23.7%) and Cochliomyia spp. (11.8%). The vagina was the most commonly reported anatomical location of UGM for women, and the urogenital tract was the most commonly reported location for men. Thirteen cases were reported from rural areas and eight cases from urban areas; the location of other cases was not specified. The incidence of UGM is likely to be substantially underestimated when evaluated based on published case reports. Epidemiological studies, such as questionnaires to medical doctors, could help to gather the necessary baseline data on the occurrence of UGM., (Copyright © 2019 Elsevier B.V. All rights reserved.)
Published: 2019
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47. Potent in vitro antileishmanial activity of a nanoformulation of cisplatin with carbon nanotubes against Leishmania major.

Author: Akhtari J, Faridnia R, Kalani H, Bastani R, Fakhar M, Rezvan H, and Beydokhti AK
Subjects: Cisplatin chemistry, Inhibitory Concentration 50, Life Cycle Stages, Meglumine Antimoniate pharmacology, Antiprotozoal Agents pharmacology, Cisplatin pharmacology, Leishmania major drug effects, Nanotubes, Carbon chemistry
Abstract: Objectives: The aim of this study was to evaluate the cytotoxicity and antileishmanial activity of cisplatin-bonded carbon nanotubes both against promastigotes and amastigotes of Leishmania major in vitro., Methods: Cisplatin-bonded single-walled carbon nanotubes (CP-SWCNT) and cisplatin-bonded multi-walled carbon nanotubes (CP-MWCNT) were considered as test compounds. In addition, SWCNT, MWCNT, free cisplatin and meglumine antimoniate (Glucantime ® ) were considered as controls. The effect of each compound was evaluated both on promastigote and amastigote stages of L. major and the results were compared., Results: There was a statistically significant difference between the half-maximal inhibitory concentration (IC 50 ) of CP-SWCNT and each of the controls, including SWCNT, cisplatin and Glucantime ® (P<0.05). In addition, IC 50 values of CP-MWCNT and each of the controls, including MWCNT, cisplatin and Glucantime ® , were significantly different both for promastigotes and amastigotes (P<0.05). However, the selectivity index (SI) of CP-SWCNT was <10 (5.23), indicating that this compound is not completely safe. Moreover, the SI values of CP-MWCNT (12.54) and Glucantime ® (16.28) were >10, indicating the selective effect of these two compounds on the parasite. Moreover, the IC 50 of CP-MWCNT (0.11±0.09μM) for amastigotes was 41-fold lower than that of Glucantime ® (4.52±1.31μM), suggesting that a lower dose of CP-MWCNT in comparison with Glucantime ® is required to kill 50% of amastigotes., Conclusions: According to the potent in vitro antileishmanial activity of CP-MWCNT at low concentration against L. major, we suggest that they are evaluated in an animal model., (Copyright © 2018 International Society for Chemotherapy of Infection and Cancer. Published by Elsevier Ltd. All rights reserved.)
Published: 2019
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48. Evaluating of Wistar rat and BALB/c mouse as animal models for congenital, cerebral and ocular toxoplasmosis.

Author: Sharif M, Faridnia R, Sarvi S, Gholami S, Kalani H, and Daryani A
Subjects: Animals, Biological Assay, Brain parasitology, Eye parasitology, Female, Mice, Pregnancy, Rats, Toxoplasma isolation & purification, Toxoplasmosis, Animal, Disease Models, Animal, Mice, Inbred BALB C, Rats, Wistar, Toxoplasmosis, Cerebral, Toxoplasmosis, Congenital, Toxoplasmosis, Ocular
Abstract: This study was conducted to evaluate the potential of cyst production by Toxoplasma (T.) gondii, RH strain, in Wistar rat and BALB/c mouse and the purpose of this study was to introduce an animal model suitable for congenital, cerebral, and ocular toxoplasmosis. The mice and rats, considered as cerebral and ocular toxoplasmosis models, were intraperitoneally infected by different number of the parasite and their eyes and brain were evaluated for the presence of T. gondii cyst using the microscopic examination and the bioassay method. Moreover, the pregnant mice and rats, considered as congenital toxoplasmosis models, were intraperitoneally infected by different number of the parasite and their infants were examined by the method mentioned above. The best result for the cerebral toxoplasmosis model was observed in the rats infected with the 107 parasites, so that all infants (100%) were infected with the parasite when examined using the bioassay method. Furthermore, the best result was observed for the congenital cerebral toxoplasmosis model with 100% infection rate in the infants born to mothers infected with the 107 parasites. Overall, just few the ocular samples were positive using bioassay method. The best result in the current study was for the congenital cerebral toxoplasmosis model where the pregnant rats were infected with the 107 parasites and all infants were infected (100%). Therefore, these infants can be used as a congenital cerebral toxoplasmosis model when they are in the fetal stage, and can be used as a cerebral toxoplasmosis model one month after birth.
Published: 2018
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49. Vaccination against Toxoplasma gondii using rhoptry antigens: a systematic review.

Author: Faridnia R, Daryani A, Sarvi S, Sharif M, and Kalani H
Subjects: Animals, Antibodies, Protozoan immunology, Humans, Immunization methods, Protozoan Proteins immunology, Protozoan Vaccines immunology, Recombinant Proteins immunology, Vaccination methods, Vaccines, DNA immunology, Antigens, Protozoan immunology, Toxoplasma immunology, Toxoplasmosis, Animal immunology
Abstract: Toxoplasma gondii is an obligate intracellular parasitic protozoan that infects a wide variety of vertebrates as intermediate hosts. The aim of the current systematic review study is to clarify the latest status of studies in the literature regarding rhoptry-associated recombinant proteins or rhoptry-associated recombinant DNAs as potential vaccines against toxoplasmosis. The search was performed systematically in 8 databases, four in English and four in Persian, up to February 2017. Overall, ROP2 was the most commonly used ROPs in DNA vaccines (27.27%) and protein vaccines (6.81%). Furthermore, regarding the type of adjuvants, route and dose of vaccination, animal models, challenge methods, and measurement of immune responses has been discussed in the text. It is hoped that this article help researchers to conduct more effective studies in the field of immunization against T. gondii., (Copyright © 2018 Elsevier Ltd. All rights reserved.)
Published: 2018
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50. Investigating in vitro anti-leishmanial effects of silibinin and silymarin on Leishmania major

Author: Faridnia R, Kalani H, Fakhar M, and Akhtari J
Subjects: Animals, Cell Line, Dose-Response Relationship, Drug, Macrophages drug effects, Macrophages parasitology, Mice, Phytotherapy, Silybin, Silymarin administration & dosage, Leishmania major drug effects, Silymarin pharmacology
Abstract: Cutaneous leishmaniosis is an important zoonotic disease caused by various Leishmania species. The aim of this study was to investigate the effects of silibinin and silymarin on the in vitro growth and proliferation of promastigotes and amastigotes of Leishmania major compared to glucantime-treated parasites. The promastigotes and amastigotes of this parasite were treated with the two drugs, silibinin and silymarin, in several concentrations (25–100 μM). The highest effect on promastigotes was for silymarin in concentration of 100 μM with 90% and 91% death rate at hours 48 and 72, respectively. Regarding amastigotes, the highest effect at 48 hours was for silibinin in concentration of 100 μM with 35% death rate. However, at 72 hours, silymarin showed the highest effect with 63% death rate in concentration of 100 μM. The highest observed maximal 50% lethal concentration (LC50) for promastigotes was for silymarin with 19.34 μM at 48 hours and 18.22 μM at 72 hours. Likewise, maximal LC50 for amastigotes was for silymarin with 191 μM at 48 hours and 24.27 μM at 72 hours. Our findings demonstrated that both medications have suitable effects like Glucantime® on the parasite in vitro. Therefore, clinical assessment of the anti-leishmanial activity of silibinin and silymarin for treating the dermal lesions caused by L. major is recommended.
Published: 2018
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