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653 results on '"Kaiserling, E."'

4. Implications of bevacizumab on vascular endothelial growth factor and endostatin in human choroidal neovascularisation

Author

Tatar, O., Shinoda, K., Kaiserling, E., Claes, C., Eckardt, C., Eckert, T., Pertile, G., Boeyden, V., Scharioth, G.B., Yoeruek, E., Szurman, P., Bartz-Schmidt, K.U., and Grisanti, S.

Subjects
Vascular endothelial growth factor -- Physiological aspects, Vascular endothelial growth factor -- Research, Endostatin -- Dosage and administration, Endostatin -- Physiological aspects, Endostatin -- Research, Neovascularization -- Care and treatment, Neovascularization -- Research, Macular degeneration -- Care and treatment, Macular degeneration -- Research, Health
Published
2009

12. Extranodal marginal zone B cell lymphoma of MALT type involving the mucosa of both the urinary bladder and stomach. (Letters to JCP)

Author

Krober, S.M., Aepinus, C., Ruck, P., Muller-Hermelink, H-K, Horny, H-P, and Kaiserling, E.

Subjects
Methods, Surgery -- Methods, Bladder cancer -- Methods, Lymphomas -- Methods
Abstract

Primary lymphoma of the urinary bladder is a very rare tumour. A bladder tumour was found in a 57 year old man with obstructive dysuria. It was found by histological [...]

Published
2002

29. Mastocytosis: reactive or neoplastic?

Author

Krober, S M, Horny, H-P, Ruck, P, Kammerer, U, Geiselhart, A, Handgretinger, R, Griesser, H, Menke, D M, and Kaiserling, E

Published
1997

34. Spleen findings in generalized mastocytosis: a clinicopathologic study

Author

Horny, H.-P., Ruck, M.T., and Kaiserling, E.

Subjects
Mast cell disease -- Complications, Splenomegaly -- Diagnosis, Spleen -- Cytology, Health
Abstract

Background. Little information regarding the morphologic findings of the spleen in generalized mastocytosis (GM) is available and no comprehensive review of the literature on this subject has been published. Methods. The authors reviewed their records to study the macroscopic and microscopic features of the spleen in 53 patients; the authors also studied these features in 135 patients reported in the literature. Thus, a total of 188 patients with GM were studied. Results. Splenomegaly was noted in 72% of the patients, including 71% of the patients from the authors' files and 73% of the patients reported in the literature. The spleen weight, recorded in 39 of the patients, ranged from 160 to 2300 g; in 29 (80%) patients the spleen weighed more than 500 g and in 4 (10%) patients, more than 2000 g. However, mast cell (MC) infiltration of the spleen was recorded in only 65 (34%) patients (patients from authors' records, 39%; patients reported in literature, 32%). The following combinations were extremely rare: splenomegaly without evidence of MC infiltration (n = 1); and histologic evidence of MC infiltration in the absence of splenomegaly (n = 2). The histologic findings of the spleen could be assessed in nine of the patients from the authors' files, eight of whom had MC infiltration. In four patients, infiltration was diffuse a confined mainly to the red pulp; in the other four patients, it was more focal and involved mainly the white pulp. Spleen plasmacytosis was found in eight patients, eosinophilia in five, hemosiderosis in seven, and fibrosis in six. Concurrent acute nonlymphoblastic leukemia was diagnosed in four patients, none of whom had the skin lesions of urticaria pigmentosa. Conclusions. The author's findings show that (1) splenomegaly in a common finding in GM and often is pronounced; (2) MC infiltration probably is the most important factor in the pathogenesis of splenomegaly in this disease; and (3) two different patterns of MC infiltration (diffuse and focal) can be identified in GM. Cancer 1992; 70:459-468.

Published
1992

44. Primäres Plasmozytom (plasmozytisches Lymphom) des Lymphknotens: Differentialdiagnose nodaler plasmazellulärer Proliferate

Author

Steinke B, Hans-Peter Horny, Menke Dm, and Kaiserling E

Subjects
Pathology, medicine.medical_specialty, business.industry, Hepatosplenomegaly, General Medicine, Plasma cell, medicine.disease, Asymptomatic, Lymphoma, medicine.anatomical_structure, medicine, Plasmacytoma, medicine.symptom, Differential diagnosis, business, Lymph node, Multiple myeloma
Abstract

HISTORY AND CLINICAL FINDINGS: A 60-year-old man was found on routine examination to have an enlarged, firm, cervical lymph node. He looked older than his age and his general condition was poor. He had no fever, nocturnal sweating or weight loss. Further examination revealed no hepatosplenomegaly on palpation, but numerous enlarged cervical lymph nodes were palpable. INVESTIGATIONS: Histological investigation of a cervical lymph node revealed a marked increase in slightly pleomorphic plasma cells with monotypic expression of IgM-kappa. Multiple myeloma was excluded on the basis of histological and cytological findings in the bone marrow. Serology revealed a mild antibody deficiency syndrome (gamma-globulin 7.8%) with signs of acute inflammation and an increase in alpha 2-globulin. There was no evidence of a monoclonal gammopathy on electrophoresis. A diagnosis of primary nodal plasmacytoma was made. COURSE: As the patient was asymptomatic at diagnosis he was not given chemotherapy. There was no evidence of tumour progression at follow-up examination two months later. His progress will be monitored closely. CONCLUSION: This patient's history is consistent with the prognosis generally associated with primary nodal plasmacytoma that is much better than that of multiple myeloma.

Published
2008
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