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2. Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement

Author

Petersenn, Stephan, Fleseriu, Maria, Casanueva, Felipe F., Giustina, Andrea, Biermasz, Nienke, Biller, Beverly M. K., Bronstein, Marcello, Chanson, Philippe, Fukuoka, Hidenori, Gadelha, Monica, Greenman, Yona, Gurnell, Mark, Ho, Ken K. Y., Honegger, Jürgen, Ioachimescu, Adriana G., Kaiser, Ursula B., Karavitaki, Niki, Katznelson, Laurence, Lodish, Maya, Maiter, Dominique, Marcus, Hani J., McCormack, Ann, Molitch, Mark, Muir, Christopher A., Neggers, Sebastian, Pereira, Alberto M., Pivonello, Rosario, Post, Kalmon, Raverot, Gerald, Salvatori, Roberto, Samson, Susan L., Shimon, Ilan, Spencer-Segal, Joanna, Vila, Greisa, Wass, John, and Melmed, Shlomo

Published
2023
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3. Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification

Author

Ho, Ken K. Y., Kaiser, Ursula B., Chanson, Phillippe, Gadelha, Monica, Wass, John, Nieman, Lynnette, Little, Andrew, Aghi, Manish K., Raetzman, Lori, Post, Kalmon, Raverot, Gerald, Borowsky, Alexander D., Erickson, Dana, Castaño, Justo P., Laws, Edward R., Zatelli, Maria Chiara, Sisco, Jill, Esserman, Laura, Yuen, Kevin C. J., Reincke, Martin, and Melmed, Shlomo

Published
2023
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6. OSR1 disruption contributes to uterine factor infertility via impaired Mullerian duct development and endometrial receptivity

Author

Lofrano-Porto, Adriana, Pereira, Sidney Alcantara, Dauber, Andrew, Bloom, Jordana C.B., Fontes, Audrey N., Asimow, Naomi, de Moraes, Olivia Laquis, Araujo, Petra Ariadne T., Abreu, Ana Paula, Guo, Michael H., De Oliveira, Silviene F., Liu, Han, Lee, Charles, Kuohung, Wendy, Coelho, Michella S., Carroll, Rona S., Jiang, Rulang, and Kaiser, Ursula B.

Subjects
Thermo Fisher Scientific Inc., Infertility, Scientific equipment and supplies industry, Pregnancy, Embryonic development, Genes, Genetic engineering, Estrogen, Genetically modified organisms, Health care industry
Abstract

Three sisters, born from consanguineous parents, manifested a unique Mullerian anomaly characterized by uterine hypoplasia with thin estrogen-unresponsive endometrium and primary amenorrhea, but with spontaneous tubal pregnancies. Through whole-exome sequencing followed by comprehensive genetic analysis, a missense variant was identified in the OSR1 gene. We therefore investigated OSR1/OSR1 expression in postpubertal human uteri, and the prenatal and postnatal expression pattern of Osr1/Osr1 in murine developing Mullerian ducts (MDs) and endometrium, respectively. We then investigated whether Osr1 deletion would affect MD development, using WT and genetically engineered mice. Human uterine OSR1/OSR1 expression was found primarily in the endometrium. Mouse Osr1 was expressed prenatally in MDs and Wolffian ducts (WDs), from rostral to caudal segments, in E13.5 embryos. MDs and WDs were absent on the left side and MDs were rostrally truncated on the right side of E13.5 [Osr1.sup.-/-] embryos. Postnatally, Osr1 was expressed in mouse uteri throughout their lifespan, peaking at postnatal days 14 and 28. Osr1 protein was present primarily in uterine luminal and glandular epithelial cells and in the epithelial cells of mouse oviducts. Through this translational approach, we demonstrated that OSR1 in humans and mice is important for MD development and endometrial receptivity and may be implicated in uterine factor infertility., Introduction The Mullerian ducts (MD) are paired embryonic structures that arise from the mesoderm-derived invaginations of the coelomic epithelium into the mesonephros and ultimately develop into segments of the female [...]

Published
2023
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7. Author Correction: Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement

Author

Petersenn, Stephan, Fleseriu, Maria, Casanueva, Felipe F., Giustina, Andrea, Biermasz, Nienke, Biller, Beverly M. K., Bronstein, Marcello, Chanson, Philippe, Fukuoka, Hidenori, Gadelha, Monica, Greenman, Yona, Gurnell, Mark, Ho, Ken K. Y., Honegger, Jürgen, Ioachimescu, Adriana G., Kaiser, Ursula B., Karavitaki, Niki, Katznelson, Laurence, Lodish, Maya, Maiter, Dominique, Marcus, Hani J., McCormack, Ann, Molitch, Mark, Muir, Christopher A., Neggers, Sebastian, Pereira, Alberto M., Pivonello, Rosario, Post, Kalmon, Raverot, Gerald, Salvatori, Roberto, Samson, Susan L., Shimon, Ilan, Spencer-Segal, Joanna, Vila, Greisa, Wass, John, and Melmed, Shlomo

Published
2024
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8. Rare variants in the MECP2 gene in girls with central precocious puberty: a translational cohort study

Author

Canton, Ana P M, Tinano, Flávia R, Guasti, Leonardo, Montenegro, Luciana R, Ryan, Fiona, Shears, Deborah, de Melo, Maria Edna, Gomes, Larissa G, Piana, Mariana P, Brauner, Raja, Espino-Aguilar, Rafael, Escribano-Muñoz, Arancha, Paganoni, Alyssa, Read, Jordan E, Korbonits, Márta, Seraphim, Carlos E, Costa, Silvia S, Krepischi, Ana Cristina, Jorge, Alexander A L, David, Alessia, Kaisinger, Lena R, Ong, Ken K, Perry, John R B, Abreu, Ana Paula, Kaiser, Ursula B, Argente, Jesús, Mendonca, Berenice B, Brito, Vinicius N, Howard, Sasha R, and Latronico, Ana Claudia

Published
2023
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11. Connecting nutritional deprivation and pubertal inhibition via GRK2-mediated repression of kisspeptin actions in GnRH neurons

Author

Perdices-Lopez, Cecilia, Avendaño, María S., Barroso, Alexia, Gaytán, Francisco, Ruiz-Pino, Francisco, Vázquez, Maria J., Leon, Silvia, Song, Yong Bhum, Sobrino, Veronica, Heras, Violeta, Romero-Ruiz, Antonio, Roa, Juan, Mayor, Federico, Jr, Murga, Cristina, Pinilla, Leonor, Kaiser, Ursula B., and Tena-Sempere, Manuel

Published
2022
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14. Consensus on diagnosis and management of Cushing's disease: a guideline update

Author

Fleseriu, Maria, Auchus, Richard, Bancos, Irina, Ben-Shlomo, Anat, Bertherat, Jerome, Biermasz, Nienke R, Boguszewski, Cesar L, Bronstein, Marcello D, Buchfelder, Michael, Carmichael, John D, Casanueva, Felipe F, Castinetti, Frederic, Chanson, Philippe, Findling, James, Gadelha, Mônica, Geer, Eliza B, Giustina, Andrea, Grossman, Ashley, Gurnell, Mark, Ho, Ken, Ioachimescu, Adriana G, Kaiser, Ursula B, Karavitaki, Niki, Katznelson, Laurence, Kelly, Daniel F, Lacroix, André, McCormack, Ann, Melmed, Shlomo, Molitch, Mark, Mortini, Pietro, Newell-Price, John, Nieman, Lynnette, Pereira, Alberto M, Petersenn, Stephan, Pivonello, Rosario, Raff, Hershel, Reincke, Martin, Salvatori, Roberto, Scaroni, Carla, Shimon, Ilan, Stratakis, Constantine A, Swearingen, Brooke, Tabarin, Antoine, Takahashi, Yutaka, Theodoropoulou, Marily, Tsagarakis, Stylianos, Valassi, Elena, Varlamov, Elena V, Vila, Greisa, Wass, John, Webb, Susan M, Zatelli, Maria C, and Biller, Beverly M K

Published
2021
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15. Panhypopituitarism

Author

Abreu, Ana Paula, Kaiser, Ursula B., Garg, Rajesh K., editor, Hennessey, James V., editor, Malabanan, Alan Ona, editor, and Garber, Jeffrey R., editor

Published
2020
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16. Pituitary Apoplexy

Author

Abreu, Ana Paula, Kaiser, Ursula B., Garg, Rajesh K., editor, Hennessey, James V., editor, Malabanan, Alan Ona, editor, and Garber, Jeffrey R., editor

Published
2020
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18. List of contributors

Author

Abreu, Ana Paula, primary, Allora, Agnese, additional, Bashari, Waiel A., additional, Beckers, Albert, additional, Ben-Shlomo, Anat, additional, Bichet, Daniel G., additional, Binart, Nadine, additional, Brière, Jonathan, additional, Bronstein, Marcello D., additional, Brown, Paul D., additional, Chaker, Layal, additional, Chanson, Philippe, additional, Daly, Adrian F., additional, Dekkers, Olaf M., additional, Drouin, Jacques, additional, Fleseriu, Maria, additional, Frara, Stefano, additional, Gadelha, Mônica R., additional, Gaston, Lindsey S., additional, Gillett, Daniel, additional, Giustina, Andrea, additional, Glezer, Andrea, additional, Greenman, Yona, additional, Gurnell, Mark, additional, Herman-Bonert, Vivien S., additional, Kaiser, Ursula B., additional, Karavitaki, Niki, additional, Kasuki, Leandro, additional, Korbonits, Márta, additional, Kovacs, Kalman, additional, Kowalchuk, Roman O., additional, MacFarlane, James, additional, Maiter, Dominique, additional, Majzoub, Joseph A., additional, Mamelak, Adam N., additional, Marques, Pedro, additional, Melmed, Shlomo, additional, Mortini, Pietro, additional, Moshkin, Olga, additional, Paragliola, Rosa Maria, additional, Peeters, Robin P., additional, Pereira, Alberto M., additional, Raverot, Gérald, additional, Rotondo, Fabio, additional, Salvatori, Roberto, additional, Scoffings, Daniel, additional, Sheehan, Jason P., additional, Spina, Alfio, additional, Syro, Luis V., additional, Takahashi, Yutaka, additional, Trifiletti, Daniel M., additional, Varlamov, Elena V., additional, Wass, John A.H., additional, Wildemberg, Luiz Eduardo, additional, and Yamamoto, Masaaki, additional

Published
2022
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19. Consensus on criteria for acromegaly diagnosis and remission

Author

Giustina, Andrea, Biermasz, Nienke, Casanueva, Felipe F., Fleseriu, Maria, Mortini, Pietro, Strasburger, Christian, van der Lely, A. J., Wass, John, Melmed, Shlomo, Banfi, Giuseppe, Barkan, Ariel, Beckers, Albert, Bidlingmaier, Martin, Boguszewski, Cesar, Brue, Thierry, Buchfelder, Michael, Chanson, Philippe, Chiloiro, Sabrina, Colao, Annamaria, Coopmans, Eva, Esposito, Daniela, Ferone, Diego, Frara, Stefano, Gadelha, Mônica, Geer, Eliza B., Ghigo, Ezio, Greenman, Yona, Gurnell, Mark, Ho, Ken, Ioachimescu, Adriana, Johannsson, Gudmundur, Jørgensen, Jens Otto, Kaiser, Ursula B., Karavitaki, Niki, Katznelson, Laurence, Lamberts, Stephen, Losa, Marco, Luger, Anton, Luque, Raúl, Maffei, Pietro, Marazuela, Mónica, Neggers, Sebastian, Pereira, Alberto, Persani, Luca, Petersenn, Stephan, Reincke, Martin, Salvatori, Roberto, Samson, Susan N., Schilbach, Katharina, Shimon, Ilan, Tsagarakis, Styliano, Zatelli, Maria Chiara, Null, Null, Chiloiro, Sabrina (ORCID:0000-0001-9241-2392), Giustina, Andrea, Biermasz, Nienke, Casanueva, Felipe F., Fleseriu, Maria, Mortini, Pietro, Strasburger, Christian, van der Lely, A. J., Wass, John, Melmed, Shlomo, Banfi, Giuseppe, Barkan, Ariel, Beckers, Albert, Bidlingmaier, Martin, Boguszewski, Cesar, Brue, Thierry, Buchfelder, Michael, Chanson, Philippe, Chiloiro, Sabrina, Colao, Annamaria, Coopmans, Eva, Esposito, Daniela, Ferone, Diego, Frara, Stefano, Gadelha, Mônica, Geer, Eliza B., Ghigo, Ezio, Greenman, Yona, Gurnell, Mark, Ho, Ken, Ioachimescu, Adriana, Johannsson, Gudmundur, Jørgensen, Jens Otto, Kaiser, Ursula B., Karavitaki, Niki, Katznelson, Laurence, Lamberts, Stephen, Losa, Marco, Luger, Anton, Luque, Raúl, Maffei, Pietro, Marazuela, Mónica, Neggers, Sebastian, Pereira, Alberto, Persani, Luca, Petersenn, Stephan, Reincke, Martin, Salvatori, Roberto, Samson, Susan N., Schilbach, Katharina, Shimon, Ilan, Tsagarakis, Styliano, Zatelli, Maria Chiara, Null, Null, and Chiloiro, Sabrina (ORCID:0000-0001-9241-2392)

Abstract

Purpose The 14th Acromegaly Consensus Conference was convened to consider biochemical criteria for acromegaly diagnosis and evaluation of therapeutic efficacy.Methods Fifty-six acromegaly experts from 16 countries reviewed and discussed current evidence focused on biochemical assays; criteria for diagnosis and the role of imaging, pathology, and clinical assessments; consequences of diagnostic delay; criteria for remission and recommendations for follow up; and the value of assessment and monitoring in defining disease progression, selecting appropriate treatments, and maximizing patient outcomes.Results In a patient with typical acromegaly features, insulin-like growth factor (IGF)-I > 1.3 times the upper limit of normal for age confirms the diagnosis. Random growth hormone (GH) measured after overnight fasting may be useful for informing prognosis, but is not required for diagnosis. For patients with equivocal results, IGF-I measurements using the same validated assay can be repeated, and oral glucose tolerance testing might also be useful. Although biochemical remission is the primary assessment of treatment outcome, biochemical findings should be interpreted within the clinical context of acromegaly. Follow up assessments should consider biochemical evaluation of treatment effectiveness, imaging studies evaluating residual/recurrent adenoma mass, and clinical signs and symptoms of acromegaly, its complications, and comorbidities. Referral to a multidisciplinary pituitary center should be considered for patients with equivocal biochemical, pathology, or imaging findings at diagnosis, and for patients insufficiently responsive to standard treatment approaches.Conclusion Consensus recommendations highlight new understandings of disordered GH and IGF-I in patients with acromegaly and the importance of expert management for this rare disease.

Published
2024

21. A refined rodent model of anorexia nervosa: Simulating state‐specific effects of caloric restriction and weight restoration.

Author

Rosa‐Caldwell, Megan E., Breithaupt, Lauren, Kaiser, Ursula B., Garland, Eliza, Pinkham, Sheridyn, Hancock, Madisyn, Jalkut, Sophie L., and Rutkove, Seward B.

Subjects
LOW-calorie diet, ANOREXIA nervosa, BONE density, SPRAGUE Dawley rats, SKELETAL muscle
Abstract

Current rodent models of anorexia nervosa (AN) often have accelerated weight loss that often do not allow for investigation of physiological ramifications of prolonged low weight status characteristic of AN. The purpose of this project was to refine a rodent model of AN to extend the duration of low weight status and allow for investigation of recovery. Eight‐week‐old female Sprague Dawley rats underwent 50%–60% food restriction for 30 days. Rats were group‐housed except during feeding, where AN rats were individually housed and given up to 2 h to consume food. Control (CON) rats were allowed to consume food ad libitum. To simulate recovery, a separate cohort of animals underwent the same food restriction protocol for 30 days, then rats (AN‐R) were allowed to consume food ad libitum to facilitate weight recovery for an additional 30 days. AN‐R rats were compared to age matched controls (CON‐R). AN rats lost ~15% bodyweight and were ~30% lighter than CON. Compared to CON, AN rats had ~35% lower fat content, ~18% lower bone mineral density, ~22% smaller plantaris muscle mass and ~52% smaller ovaries. Upon reintroduction of food, AN‐R rats achieved comparable bodyweights to CON‐R rats after ~10 days. However, after 30 days of recovery, AN‐R rats still had ~14% lower bone mineral density and ~11% smaller plantaris mass and ~21% smaller ovaries. This refinement of rodent AN results in physiological side effects of AN without reaching excessive weight loss requiring euthanasia. Moreover, some physiological consequences of simulated AN are not resolved with weight restoration. [ABSTRACT FROM AUTHOR]

Published
2024
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23. MKRN3 inhibits the reproductive axis through actions in kisspeptin-expressing neurons

Author

Abreu, Ana Paula, Toro, Carlos A., Song, Yong Bhum, Navarro, Victor M., Bosch, Martha A., Eren, Aysegul, Liang, Joy N., Carroll, Rona S., Latronico, Ana Claudia, Ronnekleiv, Oline K., Aylwin, Carlos F., Lomniczi, Alejandro, Ojeda, Sergio, and Kaiser, Ursula B.

Subjects
Pituitary hormones, Steroid hormones, Neurons, Health care industry
Abstract

The identification of loss-of-function mutations in MKRN3 in patients with central precocious puberty in association with the decrease in MKRN3 expression in the medial basal hypothalamus of mice before the initiation of reproductive maturation suggests that MKRN3 is acting as a brake on gonadotropin-releasing hormone (GnRH) secretion during childhood. In the current study, we investigated the mechanism by which MKRN3 prevents premature manifestation of the pubertal process. We showed that, as in mice, MKRN3 expression is high in the hypothalamus of rats and nonhuman primates early in life, decreases as puberty approaches, and is independent of sex steroid hormones. We demonstrated that Mkrn3 is expressed in Kiss1 neurons of the mouse hypothalamic arcuate nucleus and that MKRN3 repressed promoter activity of human KISS1 and TAC3, 2 key stimulators of GnRH secretion. We further showed that MKRN3 has ubiquitinase activity, that this activity is reduced by MKRN3 mutations affecting the RING finger domain, and that these mutations compromised the ability of MKRN3 to repress KISS1 and TAC3 promoter activity. These results indicate that MKRN3 acts to prevent puberty initiation, at least in part, by repressing KISS1 and TAC3 transcription and that this action may involve an MKRN3-directed ubiquitination-mediated mechanism., Introduction The identification of loss-of-function mutations in MKRN3, encoding makorin ring finger protein 3, in families with central precocious puberty (CPP) linked MKRN3 to the hypothalamic-pituitary-gonadal (HPG) axis for the [...]

Published
2020
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25. Author Correction: Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement

Author

Petersenn, Stephan, primary, Fleseriu, Maria, additional, Casanueva, Felipe F., additional, Giustina, Andrea, additional, Biermasz, Nienke, additional, Biller, Beverly M. K., additional, Bronstein, Marcello, additional, Chanson, Philippe, additional, Fukuoka, Hidenori, additional, Gadelha, Monica, additional, Greenman, Yona, additional, Gurnell, Mark, additional, Ho, Ken K. Y., additional, Honegger, Jürgen, additional, Ioachimescu, Adriana G., additional, Kaiser, Ursula B., additional, Karavitaki, Niki, additional, Katznelson, Laurence, additional, Lodish, Maya, additional, Maiter, Dominique, additional, Marcus, Hani J., additional, McCormack, Ann, additional, Molitch, Mark, additional, Muir, Christopher A., additional, Neggers, Sebastian, additional, Pereira, Alberto M., additional, Pivonello, Rosario, additional, Post, Kalmon, additional, Raverot, Gerald, additional, Salvatori, Roberto, additional, Samson, Susan L., additional, Shimon, Ilan, additional, Spencer-Segal, Joanna, additional, Vila, Greisa, additional, Wass, John, additional, and Melmed, Shlomo, additional

Published
2023
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28. FRI411 Pharmacologically Induced Hypoestrogenism And Experimentally Induced Menopause-Pattern Sleep Fragmentation Independently Influence Circulating Lipids, Heart Rate, And Blood Pressure In Women

Author

Grant, Leilah K, primary, Cohn, Aviva, additional, Crawford, Sybil, additional, Harder, Jessica, additional, Nathan, Margo D, additional, Gonsalvez, Irene, additional, Luo, Tianyu, additional, Menezes, Ellexa, additional, Roy, Ancella, additional, Wiley, Aleta, additional, Scheer, Frank A J L, additional, Klerman, Elizabeth, additional, Kaiser, Ursula B, additional, Mora, Samia, additional, Andrew Taylor, J, additional, Joffe, Hadine, additional, and Rahman, Shadab A, additional

Published
2023
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32. Familial central precocious puberty due to DLK1 deficiency: novel genetic findings and relevance of serum DLK1 levels

Author

Montenegro, Luciana, primary, Seraphim, Carlos, additional, Tinano, Flávia, additional, Piovesan, Maiara, additional, Canton, Ana P M, additional, McElreavey, Ken, additional, Brabant, Severine, additional, Boris, Natalia P, additional, Magnuson, Melissa, additional, Carroll, Rona S, additional, Kaiser, Ursula B, additional, Argente, Jesús, additional, Barrios, Vicente, additional, Brito, Vinicius N, additional, Brauner, Raja, additional, and Latronico, Ana Claudia, additional

Published
2023
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38. Effects of Sleep Fragmentation and Estradiol Decline on Cortisol in a Human Experimental Model of Menopause

Author

Cohn, Aviva Y, primary, Grant, Leilah K, additional, Nathan, Margo D, additional, Wiley, Aleta, additional, Abramson, Mathena, additional, Harder, Jessica A, additional, Crawford, Sybil, additional, Klerman, Elizabeth B, additional, Scheer, Frank A J L, additional, Kaiser, Ursula B, additional, Rahman, Shadab A, additional, and Joffe, Hadine, additional

Published
2023
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39. Validation of criteria for defining Pituitary Tumors Centers of Excellence (PTCOE)

Author

Giustina, Andrea, primary, Uygur, Melin Meliha, additional, Frara, Stefano, additional, Barkan, Ariel, additional, Biermasz, Nienke R., additional, Chanson, Philippe, additional, Freda, Pamela U., additional, Gadelha, Monica, additional, Kaiser, Ursula B., additional, Lamberts, Steven W.J., additional, Laws, Edward, additional, Nachtigall, Lisa B., additional, Popovic, Vera, additional, Reincke, Martin, additional, Strasburger, Christian, additional, Lely, Aart J. van der, additional, Wass, John A.H., additional, Melmed, Shlomo, additional, and Casanueva, Felipe F., additional

Published
2023
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41. MKRN3 inhibits puberty onset via interaction with IGF2BP1 and regulation of hypothalamic plasticity

Author

Naulé, Lydie, primary, Mancini, Alessandra, additional, Pereira, Sidney A., additional, Gassaway, Brandon M., additional, Lydeard, John R., additional, Magnotto, John C., additional, Kim, Han Kyeol, additional, Liang, Joy, additional, Matos, Cynara, additional, Gygi, Steven P., additional, Merkle, Florian T., additional, Carroll, Rona S., additional, Abreu, Ana Paula, additional, and Kaiser, Ursula B., additional

Published
2023
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42. Data from The Impact of High-Dose Glucocorticoids on the Outcome of Immune-Checkpoint Inhibitor–Related Thyroid Disorders

Author

Ma, Chanjuan, primary, Hodi, F. Stephen, primary, Giobbie-Hurder, Anita, primary, Wang, Xiaocheng, primary, Zhou, Jing, primary, Zhang, Amy, primary, Zhou, Ying, primary, Mao, Fei, primary, Angell, Trevor E., primary, Andrews, Chelsea P., primary, Hu, Jiani, primary, Barroso-Sousa, Romualdo, primary, Kaiser, Ursula B., primary, Tolaney, Sara M., primary, and Min, Le, primary

Published
2023
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43. Supplementary Data from The Impact of High-Dose Glucocorticoids on the Outcome of Immune-Checkpoint Inhibitor–Related Thyroid Disorders

Author

Ma, Chanjuan, primary, Hodi, F. Stephen, primary, Giobbie-Hurder, Anita, primary, Wang, Xiaocheng, primary, Zhou, Jing, primary, Zhang, Amy, primary, Zhou, Ying, primary, Mao, Fei, primary, Angell, Trevor E., primary, Andrews, Chelsea P., primary, Hu, Jiani, primary, Barroso-Sousa, Romualdo, primary, Kaiser, Ursula B., primary, Tolaney, Sara M., primary, and Min, Le, primary

Published
2023
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44. Novel MKRN3 Missense Mutations Associated With Central Precocious Puberty Reveal Distinct Effects on Ubiquitination

Author

Magnotto, John C, primary, Mancini, Alessandra, additional, Bird, Keisha, additional, Montenegro, Luciana, additional, Tütüncüler, Filiz, additional, Pereira, Sidney A, additional, Simas, Vitoria, additional, Garcia, Leonardo, additional, Roberts, Stephanie A, additional, Macedo, Delanie, additional, Magnuson, Melissa, additional, Gagliardi, Priscila, additional, Mauras, Nelly, additional, Witchel, Selma F, additional, Carroll, Rona S, additional, Latronico, Ana Claudia, additional, Kaiser, Ursula B, additional, and Abreu, Ana Paula, additional

Published
2023
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