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713 results on '"Kagawa, Yasuo"'

10. Awards

Author

KAGAWA, YASUO, TAKEMI, KEIZO, HOKAMA, TOMIKO, and NAKAMURA, YASUHIDE

Published
2017

18. Investigation of Maternal Diet and FADS1 Polymorphism Associated with Long-Chain Polyunsaturated Fatty Acid Compositions in Human Milk

Author

Niwa, Sakurako, primary, Kawabata, Terue, additional, Shoji, Kumiko, additional, Ogata, Hiromitsu, additional, Kagawa, Yasuo, additional, Nakayama, Kazuhiro, additional, Yanagisawa, Yoshiko, additional, Iwamoto, Sadahiko, additional, Tatsuta, Nozomi, additional, Asato, Kaname, additional, Arima, Takahiro, additional, Yaegashi, Nobuo, additional, and Nakai, Kunihiko, additional

Published
2022
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20. The Body Fat Percentage Rather Than the BMI Is Associated with the CD4 Count among HIV Positive Japanese Individuals

Author

Shoji, Kumiko, primary, Shirano, Michinori, additional, Konishi, Mitsuru, additional, Toyoshima, Yuko, additional, Matsumoto, Miyuki, additional, Goto, Tetsushi, additional, Kasamatsu, Yu, additional, Ichida, Yuji, additional, Kagawa, Yasuo, additional, Kawabata, Terue, additional, Ogata, Hiromitsu, additional, and Habu, Daiki, additional

Published
2022
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28. A single nucleotide polymorphism in the FADS1/FADS2 gene is associated with plasma lipid profiles in two genetically similar Asian ethnic groups with distinctive differences in lifestyle

Author

Nakayama, Kazuhiro, Bayasgalan, Tumenbayer, Tazoe, Fumiko, Yanagisawa, Yoshiko, Gotoh, Takaya, Yamanaka, Kazuhiro, Ogawa, Ayumi, Munkhtulga, Lkhagvasuren, Chimedregze, Ulziiburen, Kagawa, Yasuo, Ishibashi, Shun, Iwamoto, Sadahiko, and Jichi Medical University Promotion Team of a Large-scale Human Genome Bank for All over Japan

Published
2010
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30. Evaluation of oxidative stress and effectiveness of low-dose glucocorticoid therapy on exacerbation of chronic obstructive pulmonary disease

Author

Komatsu, Fumio, Kudoh, Hideki, and Kagawa, Yasuo

Subjects
Lung diseases, Obstructive -- Causes of, Lung diseases, Obstructive -- Drug therapy, Oxidative stress -- Influence, Corticosteroids -- Influence, Corticosteroids -- Properties, Metabolites -- Properties, Metabolites -- Control, Health, Seniors
Abstract

Background. Chronic obstructive pulmonary disease (COPD) and its exacerbation are considered to be related to oxidative stress. We determined the levels of reactive oxygen metabolites (ROM) and a biological antioxidant potential (BAP) in blood before and after the exacerbation. Methods. For these determinations, the Free Radical Analytical System 4 was used. Twenty-one male patients were divided into two groups. Results, Group A patients (n = 11, for whom the disease was end-stage) showed high ROM levels and low BAP levels. Meanwhile, Group B patients (n = 10, for whom the disease was not end-stage but the exacerbation was repeated) exhibited variable ROM levels corresponding to the symptoms. Before the exacerbation, ROM levels increased. After administering high-dose glucocorticoids, the exacerbation disappeared and ROM levels decreased to the baseline. To suppress the relapse, the Group B patients were medicated with low-dose glucocorticoids by inhalation and systemic administration. Then, ROM levels did not increase or the relapse did not occur. BAP levels continued to be low, and were restored after a stable state was obtained. Conclusion, Overproduction of ROM may precede exacerbation of COPD, and the low-dose glucocorticoid therapy may be effective to suppress its overproduction and to preserve COPD in a stable state.

Published
2007

31. Dietary intake in Japanese outpatients with type 2 diabetes: 2-year follow up study

Author

Kontai, Yoshiko, Horikawa, Chika, Tsuruta, Megumi, Iizuka, Tsukasa, Yamatani, Keiichi, and Kagawa, Yasuo

Subjects
2型糖尿病, 縦断研究, longitudinal study, Medical nutritional therapy, Type 2 diabetes, Dietary intakelongitudinal study, 食事療法, 食事摂取状況
Abstract

application/pdf, Journal Article, 【目的】食事療法は2型糖尿病患者の自己管理に必須であるが、その経年的な実践状況についての検討は不足している。そこで本研究では、2型糖尿病患者における2年間の食事摂取状況の実態把握を行った。【方法】外来に通院する2型糖尿病患者60名 (平均年齢：66.8歳, 男性比率：65.0%) について、食物摂取頻度調査法を用い2014年とその2年後に把握した食品群・栄養素摂取状況を経年的に比較した。【結果】対象者の調査開始時の平均値は、罹病期間：10.2 ± 6.6 年，HbA1c：7.4 ± 1.1 %，BMI（Body Mass Index）：23.6 ± 4.4 kg/m2 であった。2年後は、BMI や血糖、血中脂質に有意差はみられず、収縮期血圧のみ調査開始時より高値であった(137.3 ± 13.6 vs. 132.8 ± 14.7 mmHg, p=0.031)。食事摂取状況は、2年間でエネルギー摂取量に有意差はみられなかったが、脂質エネルギー比が増加し(25.8 ± 5.3 vs. 27.3 ± 6.2 %, p= 0.030)、食物繊維摂取量が低下した(13.8 ± 4.6 vs.12.5 ± 3.6 g, p= 0.030)。食品群別では、野菜総量は摂取量が低下し(280 ± 132 vs. 229 ± 114 g, p=0.004)、肉類摂取量が増加した(45 ± 31 vs. 57 ± 48 g, p= 0.029)。調査開始時のHbA1c 値とBMI による層別解析では、HbA1c＜7%群で食物繊維と野菜類の総量摂取量が2年後に低値となり(p=0.048, 0.001)、HbA1c≧7%群で脂質摂取量が高値であるが( p= 0.042)、脂質エネルギー比でみると有意差は認められなかった。BMI 25kg/m2 未満群では、脂質エネルギー比が2年間で増加し(p= 0.043)、食物繊維と野菜類の総量摂取量が低下し(p= 0.003, 0.003)、乳類の摂取量が増加した(p= 0.022)。BMI 25kg/m2 以上群は、エネルギーや三大栄養素摂取に有意差は認められず、食品群別で、緑黄色野菜のみ2 年後の摂取量が低値となった(p= 0.008)。【結論】外来2型糖尿病患者の2年間の食事摂取状況の変化が明らかとなった。糖尿病療養状況を考慮した、各患者の食事摂取状況の経時的な把握を行う必要性が示唆された。, Objective: The dietary intake across the ages of patients with type 2 diabetes is sparse though nutritional therapy is essential for self-managing for diabetes. We aimed to clarify 2-year dietary intake among Japanese individuals with type 2 diabetes from a community hospital-based registry. Methods: This study was analyzed in 60 patients with type 2 diabetes (Men%:65.0%, Age: 66.8y, BMI: 23.6kg/m2, HbA1c:7.4%) using the food frequency questionnaire based on food groups using paired t-test and Wilcoxon signed-rank test. Results: BMI, HbA1c, and serum lipid revels did not show significant difference over 2 years. Systolic blood pressure level in 2 years was significantly high than the value of baseline (137.3±13.6 vs. 132.8±14.7mmHg, p= 0.031). There was no significant difference in mean energy intake and proportions of protein and carbohydrate comprising total energy intake over 2 years. The proportion of fat intake increased (25.8±5.3 vs. 27.3±6.2%, p=0.030) and the fiber intake decreased in the 2 years (13.8±4.6 vs. 12.5±3.6g, p=0.030). As a dietary intake by food groups, vegetable intake was decreased (280±132 vs. 229±114g, p=0.004) and meat intake increased (45±31 vs. 57±48g, p= 0.029) in the 2 years. In addition, among patients who had HbA1c

Published
2018

38. Internet Assisted Learning of Biochemistry in Japan.

Author

Hamamoto, Toshiro and Kagawa, Yasuo

Abstract

Documents the growth of Internet use by university students in Japan. Focuses on the use of the Internet as part of the biochemistry curriculum in Japanese medical schools. (DDR)

Published
1998

43. Survey of Biochemical Education in Japanese Universities.

Author

Kagawa, Yasuo

Abstract

Reports findings of questionnaires sent to faculty in charge of biochemical education in medical schools and other programs from dentistry to agriculture. Total class hours have declined since 1984. New trends include bioethics and computer-assisted learning. Tables show trends in lecture hours, lecture content, laboratory hours, core subject ratings, and evaluation methods used. Discusses biochemistry since World War II. (PVD)

Published
1995

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