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226 results on '"Kadian-Dodov, Daniella"'

1. Integrative gene regulatory network analysis discloses key driver genes of fibromuscular dysplasia

Author

d’Escamard, Valentina, Kadian-Dodov, Daniella, Ma, Lijiang, Lu, Sizhao, King, Annette, Xu, Yang, Peng, Shouneng, V′Gangula, Bhargravi, Zhou, Yu, Thomas, Allison, Michelis, Katherine C., Bander, Emir, Bouchareb, Rihab, Georges, Adrien, Nomura-Kitabayashi, Aya, Wiener, Robert J., Costa, Kevin D., Chepurko, Elena, Chepurko, Vadim, Fava, Marika, Barwari, Temo, Anyanwu, Anelechi, Filsoufi, Farzan, Florman, Sander, Bouatia-Naji, Nabila, Schmidt, Lukas E., Mayr, Manuel, Katz, Michael G., Hao, Ke, Weiser-Evans, Mary C. M., Björkegren, Johan L. M., Olin, Jeffrey W., and Kovacic, Jason C.

Published
2024
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2. Posttraumatic Stress Disorder After Spontaneous Coronary Artery Dissection: A Report of the International Spontaneous Coronary Artery Dissection Registry.

Author

Sumner, Jennifer, Kim, Esther, Wood, Malissa, Chi, Gerald, Nolen, Jessica, Grodzinsky, Anna, Gornik, Heather, Kadian-Dodov, Daniella, Wells, Bryan, Hess, Connie, Lewey, Jennifer, Tam, Lori, Henkin, Stanislav, Orford, James, Wells, Gretchen, Kumbhani, Dharam, Lindley, Kathryn, Gibson, C, Leon, Katherine, and Naderi, Sahar

Subjects
PTSD, SCAD, health status, sleep, trauma, treatment, Female, Humans, Male, Middle Aged, Coronary Angiography, Coronary Vessel Anomalies, Coronary Vessels, Registries, Risk Factors, Stress Disorders, Post-Traumatic, Vascular Diseases
Abstract

BACKGROUND: Myocardial infarction secondary to spontaneous coronary artery dissection (SCAD) can be traumatic and potentially trigger posttraumatic stress disorder (PTSD). In a large, multicenter, registry-based cohort, we documented prevalence of lifetime and past-month SCAD-induced PTSD, as well as related treatment seeking, and examined a range of health-relevant correlates of SCAD-induced PTSD. METHODS AND RESULTS: Patients with SCAD were enrolled in the iSCAD (International SCAD) Registry. At baseline, site investigators completed medical report forms, and patients reported demographics, medical/SCAD history, psychosocial factors (including SCAD-induced PTSD symptoms), health behaviors, and health status via online questionnaires. Of 1156 registry patients, 859 patients (93.9% women; mean age, 52.3 years) completed questionnaires querying SCAD-induced PTSD. Nearly 35% (n=298) of patients met diagnostic criteria for probable SCAD-induced PTSD in their lifetime, and 6.4% (n=55) met criteria for probable past-month PTSD. Of 811 patients ever reporting any SCAD-induced PTSD symptoms, 34.8% indicated seeking treatment for this distress. However, 46.0% of the 298 patients with lifetime probable SCAD-induced PTSD diagnoses reported never receiving trauma-related treatment. Younger age at first SCAD, fewer years since SCAD, being single, unemployed status, more lifetime trauma, and history of anxiety were associated with greater past-month PTSD symptom severity in multivariable regression models. Greater past-month SCAD-induced PTSD symptoms were associated with greater past-week sleep disturbance and worse past-month disease-specific health status when adjusting for various risk factors. CONCLUSIONS: Given the high prevalence of SCAD-induced PTSD symptoms, efforts to support screening for these symptoms and connecting patients experiencing distress with empirically supported treatments are critical next steps. REGISTRATION: URL: https://www.clinicaltrials.gov; Unique identifier: NCT04496687.

Published
2024

3. Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation.

Author

Adlam, David, Berrandou, Takiy-Eddine, Georges, Adrien, Nelson, Christopher, Giannoulatou, Eleni, Henry, Joséphine, Ma, Lijiang, Blencowe, Montgomery, Turley, Tamiel, Yang, Min-Lee, Chopade, Sandesh, Finan, Chris, Braund, Peter, Sadeg-Sayoud, Ines, Iismaa, Siiri, Kosel, Matthew, Zhou, Xiang, Hamby, Stephen, Cheng, Jenny, Liu, Lu, Tarr, Ingrid, Muller, David, dEscamard, Valentina, King, Annette, Brunham, Liam, Baranowska-Clarke, Ania, Debette, Stéphanie, Amouyel, Philippe, Olin, Jeffrey, Patil, Snehal, Hesselson, Stephanie, Junday, Keerat, Kanoni, Stavroula, Aragam, Krishna, Butterworth, Adam, Tweet, Marysia, Gulati, Rajiv, Combaret, Nicolas, Kadian-Dodov, Daniella, Kalman, Jonathan, Fatkin, Diane, Hingorani, Aroon, Saw, Jacqueline, Webb, Tom, Hayes, Sharonne, Yang, Xia, Ganesh, Santhi, Olson, Timothy, Kovacic, Jason, Graham, Robert, Samani, Nilesh, and Bouatia-Naji, Nabila

Subjects
Humans, Female, Genome-Wide Association Study, Vascular Diseases, Coronary Artery Disease, Myocardial Infarction
Abstract

Spontaneous coronary artery dissection (SCAD) is an understudied cause of myocardial infarction primarily affecting women. It is not known to what extent SCAD is genetically distinct from other cardiovascular diseases, including atherosclerotic coronary artery disease (CAD). Here we present a genome-wide association meta-analysis (1,917 cases and 9,292 controls) identifying 16 risk loci for SCAD. Integrative functional annotations prioritized genes that are likely to be regulated in vascular smooth muscle cells and artery fibroblasts and implicated in extracellular matrix biology. One locus containing the tissue factor gene F3, which is involved in blood coagulation cascade initiation, appears to be specific for SCAD risk. Several associated variants have diametrically opposite associations with CAD, suggesting that shared biological processes contribute to both diseases, but through different mechanisms. We also infer a causal role for high blood pressure in SCAD. Our findings provide novel pathophysiological insights involving arterial integrity and tissue-mediated coagulation in SCAD and set the stage for future specific therapeutics and preventions.

Published
2023

8. Author Correction: Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases

Author

Georges, Adrien, Yang, Min-Lee, Berrandou, Takiy-Eddine, Bakker, Mark K., Dikilitas, Ozan, Kiando, Soto Romuald, Ma, Lijiang, Satterfield, Benjamin A., Sengupta, Sebanti, Yu, Mengyao, Deleuze, Jean-François, Dupré, Delia, Hunker, Kristina L., Kyryachenko, Sergiy, Liu, Lu, Sayoud-Sadeg, Ines, Amar, Laurence, Brummett, Chad M., Coleman, Dawn M., d’Escamard, Valentina, de Leeuw, Peter, Fendrikova-Mahlay, Natalia, Kadian-Dodov, Daniella, Li, Jun Z., Lorthioir, Aurélien, Pappaccogli, Marco, Prejbisz, Aleksander, Smigielski, Witold, Stanley, James C., Zawistowski, Matthew, Zhou, Xiang, Zöllner, Sebastian, Amouyel, Philippe, De Buyzere, Marc L., Debette, Stéphanie, Dobrowolski, Piotr, Drygas, Wojciech, Gornik, Heather L., Olin, Jeffrey W., Piwonski, Jerzy, Rietzschel, Ernst R., Ruigrok, Ynte M., Vikkula, Miikka, Warchol Celinska, Ewa, Januszewicz, Andrzej, Kullo, Iftikhar J., Azizi, Michel, Jeunemaitre, Xavier, Persu, Alexandre, Kovacic, Jason C., Ganesh, Santhi K., and Bouatia-Naji, Nabila

Published
2022
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9. Central and peripheral arterial diseases in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Ademi, Zanfina, Chang, Tara I., Clark, Tim, Cooper, Chris, Criqui, Michael, de Bhailis, Áine, De Carlo, Marco, Döhner, Wolfram, Engelman, Daniel T., Fowkes, Gerry, Green, Darren, Hamdan, Allen, Heiss, Christian, Huppert, Peter, Kadian-Dodov, Daniella, Lip, Gregory Y.H., Małyszko, Jolanta, Mark, Patrick B., Miglinas, Marius, Murray, Patrick, Reid, Chris, Rochon, Paul, Ruturi, Josiah, Saratzis, Athanasios, Sarnak, Mark J., Shanahan, Cathy M., Solá, Laura, Teichgräber, Ulf, Textor, Stephen C., Toyoda, Kazunori, Yee-Moon Wang, Angela, Wong, Chris X., Johansen, Kirsten L., Garimella, Pranav S., Hicks, Caitlin W., Kalra, Philip A., Kelly, Dearbhla M., Martens, Sven, Matsushita, Kunihiro, Sarafidis, Pantelis, Sood, Manish M., Herzog, Charles A., Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C., and Reinecke, Holger

Published
2021
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10. Executive Summary of Standard Operating Procedures for Society for Vascular Medicine (SVM) publications.

Author

Mena-Hurtado, Carlos, Aronow, Herbert D, Beckman, Joshua, Bikdeli, Behnood, Bronas, Ulf, Castro-Dominguez, Yulanka, Chatterjee, Saurav, Elgendy, Islam Y, Kadian-Dodov, Daniella, Hogan, Shea, Sethi, Sanjum, Mohamad Yusoff, Farina, and Mukherjee, Debabrata

Subjects
MAJORITIES, GROUP decision making, PHYSICIAN practice patterns, STANDARD operating procedure, PATIENT preferences
Abstract

The Society for Vascular Medicine (SVM) has updated its Manual of Standard Operating Procedures (SOPs) for SVM Publications. The Research, Quality, and Publications Committee of SVM is responsible for developing position statements, practice guidelines, and other documents. The committee identifies potential topics through periodic assessments, considering input from stakeholders and addressing variations in clinical practice and inequalities in patient care. SVM may collaborate with other organizations in document development, following mutually agreed-upon policies and procedures. The committee also ensures conflict of interest disclosure and management, forms writing groups, and follows a structured methodology for document development. Peer review and public comment are conducted, and documents are evaluated and updated regularly to maintain quality and adherence to best practices. [Extracted from the article]

Published
2024
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11. Abstract 15281: Patient and System-Related Delays in Presentation and Invasive Coronary Angiography in Patients Presenting With Acute Myocardial Infarction Secondary to Spontaneous Coronary Artery Dissection: A Report of the ISCAD Registry

Author

Kumbhani, Dharam J, Kim, Esther S, Wood, Malissa, Leon, Katherine, Chi, Gerald C, Grodzinsky, Anna, Gornik, Heather L, Wells, Bryan, Lewey, Jennifer, Taylor, Angela, Kadian Dodov, Daniella, Hess, Connie N, Henkin, Stanislav, Lindley, Kathryn, Morris, Gretchen, Orford, James L, Tam, Lori, Norris, Samuel, Reyes, Cassandra, Alkhalfan, Fahad, Vitarello, Clara, Femnou Mbuntum, Laurette, and naderi, sahar

Published
2022
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13. Abstract 13836: Factors Associated With a Complicated Hospital Course in Patients With Spontaneous Coronary Artery Dissection: A Report of the iSCAD Registry

Author

Alkhalfan, Fahad, Wood, Malissa, naderi, sahar, Leon, Katherine, Gibson, C M, Chi, Gerald C, Grodzinsky, Anna, Gornik, Heather L, Wells, Bryan J, Lewey, Jennifer, Taylor, Angela, Kadian Dodov, Daniella, Hess, Connie N, Henkin, Stanislav, Lindley, Kathryn, Morris, Gretchen, Orford, James L, Tam, Lori, Kumbhani, Dharam J, Norris, Samuel, Reyes, Cassandra, Vitarello, Clara, and Kim, Esther S

Published
2022
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14. Abstract 13419: Racial Differences in Patients With Spontaneous Coronary Artery Dissection: A Report of the ISCAD Registry

Author

Wells, Bryan J, Kim, Esther S, naderi, sahar, Leon, Katherine, Gibson, C M, Chi, Gerald C, Grodzinsky, Anna, Gornik, Heather L, Lewey, Jennifer, Taylor, Angela, Kadian Dodov, Daniella, Hess, Connie N, Henkin, Stanislav, Lindley, Kathryn J, Morris, Gretchen, Orford, James L, Tam, Lori M, Kumbhani, Dharam J, Norris, Samuel, Reyes, Cassandra, Alkhalfan, Fahad, Vitarello, Clara, Martinez, Andrea, and Wood, Malissa

Published
2022
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15. Abstract 11377: Takotsubo Syndrome Among Patients With Spontaneous Coronary Artery Dissection: A Report of the ISCAD Registry

Author

Chi, Gerald, Kim, Esther S, naderi, sahar, Leon, Katherine, Gibson, C M, Grodzinsky, Anna, Gornik, Heather L, Wells, Bryan, Lewey, Jennifer, Taylor, Angela, Kadian Dodov, Daniella, Hess, Connie N, Henkin, Stanislav, Lindley, Kathryn, Wells, Gretchen L, Orford, James L, Tam, Lori M, Kumbhani, Dharam J, Norris, Samuel, Reyes, Cassandra, Alkhalfan, Fahad, Vitarello, Clara, and Wood, Malissa

Published
2022
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16. Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases

Author

Georges, Adrien, Yang, Min-Lee, Berrandou, Takiy-Eddine, Bakker, Mark K., Dikilitas, Ozan, Kiando, Soto Romuald, Ma, Lijiang, Satterfield, Benjamin A., Sengupta, Sebanti, Yu, Mengyao, Deleuze, Jean-François, Dupré, Delia, Hunker, Kristina L., Kyryachenko, Sergiy, Liu, Lu, Sayoud-Sadeg, Ines, Amar, Laurence, Brummett, Chad M., Coleman, Dawn M., d’Escamard, Valentina, de Leeuw, Peter, Fendrikova-Mahlay, Natalia, Kadian-Dodov, Daniella, Li, Jun Z., Lorthioir, Aurélien, Pappaccogli, Marco, Prejbisz, Aleksander, Smigielski, Witold, Stanley, James C., Zawistowski, Matthew, Zhou, Xiang, Zöllner, Sebastian, Amouyel, Philippe, De Buyzere, Marc L., Debette, Stéphanie, Dobrowolski, Piotr, Drygas, Wojciech, Gornik, Heather L., Olin, Jeffrey W., Piwonski, Jerzy, Rietzschel, Ernst R., Ruigrok, Ynte M., Vikkula, Miikka, Warchol Celinska, Ewa, Januszewicz, Andrzej, Kullo, Iftikhar J., Azizi, Michel, Jeunemaitre, Xavier, Persu, Alexandre, Kovacic, Jason C., Ganesh, Santhi K., and Bouatia-Naji, Nabila

Published
2021
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17. Migraine headache in patients with spontaneous coronary artery dissection: A report of the iSCAD Registry.

Author

Wells, Bryan J, Wood, Malissa J, O'Duffy, Anne E, Sumner, Jennifer A, Chi, Gerald, Grodzinsky, Anna, Gornik, Heather L, Kadian-Dodov, Daniella, Taylor, Angela, Hess, Connie N, Sanghavi, Monika, Henkin, Stanislav, Wells, Gretchen, Tam, Lori, Orford, James, Lindley, Kathryn, Kumbhani, Dharam J, Vitarello, Clara, Alkhalfan, Fahad, and Gibson, C Michael

Subjects
SPONTANEOUS coronary artery dissection, MIGRAINE, CAROTID artery dissections, DISABILITIES, FIBRODYSPLASIA ossificans progressiva, MYOCARDIAL infarction
Abstract

Introduction: Spontaneous coronary artery dissection (SCAD) is a nonatherosclerotic cause of myocardial infarction. Migraine headache has been reported to be common among patients with SCAD, but the degree of migraine-related disability has not been quantified. Methods: Clinical data and headache variables were obtained from the baseline assessment of the prospective, multicenter iSCAD Registry. Migraine-related disability was quantified using the self-reported Migraine Disability Assessment (MIDAS). Demographic, clinical, psychosocial, and medical characteristics from data entry forms were compared between patients with and without migraine. Results: Of the 773 patients with available data, 46% reported previous or current migraines. Those with migraines were more likely to be women (96.9% vs 90.3%, p = 0.0003). The presence of underlying carotid fibromuscular dysplasia was associated with migraine (35% vs 27%, p = 0.0175). There was not a significant association with carotid artery dissection and migraine. Current migraine frequency was less than monthly (58%), monthly (24%), weekly (16%), and daily (3%). Triptan use was reported in 32.5% of patients, and 17.5% used daily migraine prophylactic medications. Using the MIDAS to quantify disability related to migraine, 60.2% reported little or no disability, 14.4% mild, 12.7% moderate, and 12.7% severe. The mean MIDAS score was 9.9 (mild to moderate disability). Patients with SCAD had higher rates of depression and anxiety (28.2% vs 17.7% [ p = 0.0004] and 35.3% vs 26.7% [ p = 0.0099], respectively). Conclusions: Migraines are common, frequent, and a source of disability in patients with SCAD. The association between female sex, anxiety, and depression may provide some insight for potential treatment modalities. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Society Communications: 2024 Committee Updates.

Author

Cohoon, Kevin P, Kadian-Dodov, Daniella, Eberhardt, Robert, and Sharma, Aditya

Subjects
*CAREER development, *MEDICAL fellowships, *PERIPHERAL vascular diseases, *EVIDENCE gaps, *STANDARD operating procedure
Abstract

The article provides updates from various committees within the Society for Vascular Medicine (SVM). The Marketing and Communications Committee conducted a survey to determine the topics of interest for SVM members, with vascular medicine practice tools being the most popular. The Research, Quality, and Publications Committee developed a manual of standard operating procedures to ensure consistency in the development of SVM documents. The Fellowship Committee created a Vascular Medicine Fellowship Training Program Toolkit to assist in the development of fellowship programs. The Membership Committee introduced the SVM International Membership, offering affordable access and exclusive benefits to vascular professionals worldwide. [Extracted from the article]

Published
2024
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24. First international consensus on the diagnosis and management of fibromuscular dysplasia

Author

Gornik, Heather L., Persu, Alexandre, Adlam, David, Aparicio, Lucas S., Azizi, Michel, Boulanger, Marion, Bruno, Rosa M., De Leeuw, Peter, Fendrikova-Mahlay, Natalia, Froehlich, James, Ganesh, Santhi K., Gray, Bruce H., Jamison, Cathlin, Januszewicz, Andrzej, Jeunemaitre, Xavier, Kadian-Dodov, Daniella, Kim, Esther S.H., Kovacic, Jason C., Mace, Pamela, Morganti, Alberto, Sharma, Aditya, Southerland, Andrew M., Touzé, Emmanuel, Van der Niepen, Patricia, Wang, Jiguang, Weinberg, Ido, Wilson, Scott, Olin, Jeffrey W., and Plouin, Pierre-Francois

Published
2019
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27. SVM Communications: Membership spotlight and highlights from the Fellows and Advanced Practice Provider course.

Author

Kadian-Dodov, Daniella, Keefe, Joel G, Henkin, Stanislav, and Ratchford, Elizabeth V

Subjects
*MEDICAL students, *ARTERIAL dissections, *PERIPHERAL vascular diseases
Abstract

Graph: Joel G KeefeUniversity of South Carolina School of MedicineColumbia, SC The Society for Vascular Medicine (SVM) recently launched a new "Student Member" membership category. Highlights from the 2023 SVM Fellows and Advanced Practice Provider course B Daniella Kadian-Dodov, MD, FSVM b The 9 SP th sp annual SVM Fellows and Advance Practice Provider (APP) course was held in Atlanta, Georgia on March 18-19, 2023. [Extracted from the article]

Published
2023
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29. Subclinical Atherosclerosis in Young, Socioeconomically Vulnerable Hispanic and Non-Hispanic Black Adults

Author

Iglesies-Grau, Josep, primary, Fernandez-Jimenez, Rodrigo, additional, Diaz-Munoz, Raquel, additional, Jaslow, Risa, additional, de Cos-Gandoy, Amaya, additional, Santos-Beneit, Gloria, additional, Hill, Christopher A., additional, Turco, Alexandra, additional, Kadian-Dodov, Daniella, additional, Kovacic, Jason C., additional, Fayad, Zahi A., additional, and Fuster, Valentin, additional

Published
2022
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30. The HDAC9-associated risk locus promotes coronary artery disease by governing TWIST1

Author

Ma, Lijiang, primary, Bryce, Nicole S., additional, Turner, Adam W., additional, Di Narzo, Antonio F., additional, Rahman, Karishma, additional, Xu, Yang, additional, Ermel, Raili, additional, Sukhavasi, Katyayani, additional, d’Escamard, Valentina, additional, Chandel, Nirupama, additional, V’Gangula, Bhargavi, additional, Wolhuter, Kathryn, additional, Kadian-Dodov, Daniella, additional, Franzen, Oscar, additional, Ruusalepp, Arno, additional, Hao, Ke, additional, Miller, Clint L., additional, Björkegren, Johan L. M., additional, and Kovacic, Jason C., additional

Published
2022
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31. Author Correction: Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.

Author

UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Département cardiovasculaire, Georges, Adrien, Yang, Min-Lee, Berrandou, Takiy-Eddine, Bakker, Mark K, Dikilitas, Ozan, Kiando, Soto Romuald, Ma, Lijiang, Satterfield, Benjamin A, Sengupta, Sebanti, Yu, Mengyao, Deleuze, Jean-François, Dupré, Delia, Hunker, Kristina L, Kyryachenko, Sergiy, Liu, Lu, Sayoud-Sadeg, Ines, Amar, Laurence, Brummett, Chad M, Coleman, Dawn M, d'Escamard, Valentina, de Leeuw, Peter, Fendrikova-Mahlay, Natalia, Kadian-Dodov, Daniella, Li, Jun Z, Lorthioir, Aurélien, Pappaccogli, Marco, Prejbisz, Aleksander, Smigielski, Witold, Stanley, James C, Zawistowski, Matthew, Zhou, Xiang, Zöllner, Sebastian, FEIRI investigators, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group, MEGASTROKE, Amouyel, Philippe, De Buyzere, Marc L, Debette, Stéphanie, Dobrowolski, Piotr, Drygas, Wojciech, Gornik, Heather L, Olin, Jeffrey W, Piwonski, Jerzy, Rietzschel, Ernst R, Ruigrok, Ynte M, Vikkula, Miikka, Warchol Celinska, Ewa, Januszewicz, Andrzej, Kullo, Iftikhar J, Azizi, Michel, ARCADIA Investigators, Jeunemaitre, Xavier, Persu, Alexandre, Kovacic, Jason C, Ganesh, Santhi K, Bouatia-Naji, Nabila, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Département cardiovasculaire, Georges, Adrien, Yang, Min-Lee, Berrandou, Takiy-Eddine, Bakker, Mark K, Dikilitas, Ozan, Kiando, Soto Romuald, Ma, Lijiang, Satterfield, Benjamin A, Sengupta, Sebanti, Yu, Mengyao, Deleuze, Jean-François, Dupré, Delia, Hunker, Kristina L, Kyryachenko, Sergiy, Liu, Lu, Sayoud-Sadeg, Ines, Amar, Laurence, Brummett, Chad M, Coleman, Dawn M, d'Escamard, Valentina, de Leeuw, Peter, Fendrikova-Mahlay, Natalia, Kadian-Dodov, Daniella, Li, Jun Z, Lorthioir, Aurélien, Pappaccogli, Marco, Prejbisz, Aleksander, Smigielski, Witold, Stanley, James C, Zawistowski, Matthew, Zhou, Xiang, Zöllner, Sebastian, FEIRI investigators, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group, MEGASTROKE, Amouyel, Philippe, De Buyzere, Marc L, Debette, Stéphanie, Dobrowolski, Piotr, Drygas, Wojciech, Gornik, Heather L, Olin, Jeffrey W, Piwonski, Jerzy, Rietzschel, Ernst R, Ruigrok, Ynte M, Vikkula, Miikka, Warchol Celinska, Ewa, Januszewicz, Andrzej, Kullo, Iftikhar J, Azizi, Michel, ARCADIA Investigators, Jeunemaitre, Xavier, Persu, Alexandre, Kovacic, Jason C, Ganesh, Santhi K, and Bouatia-Naji, Nabila

Abstract

No abstract available

Published
2022

32. Diseases of the Aorta and Kidney Disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Author

UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, Sarafidis, Pantelis, Martens, Sven, Saratzis, Athanasios, Kadian-Dodov, Daniella, Murray, Patrick T, Shanahan, Catherine M, Hamdan, Allen D, Engelman, Daniel T, Teichgräber, Ulf, Herzog, Charles A, Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C, Reinecke, Holger, Johansen, Kirsten, for Conference Participants, UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, Sarafidis, Pantelis, Martens, Sven, Saratzis, Athanasios, Kadian-Dodov, Daniella, Murray, Patrick T, Shanahan, Catherine M, Hamdan, Allen D, Engelman, Daniel T, Teichgräber, Ulf, Herzog, Charles A, Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C, Reinecke, Holger, Johansen, Kirsten, and for Conference Participants

Abstract

Chronic kidney disease (CKD) is an independent risk factor for the development of abdominal aortic aneurysm (AAA), as well as for cardiovascular and renal events and all-cause mortality following surgery for AAA or thoracic aortic dissection. In addition, the incidence of acute kidney injury (AKI) after any aortic surgery is particularly high, and this AKI per se is independently associated with future cardiovascular events and mortality. On the other hand, both development of AKI after surgery and the long-term evolution of kidney function differ significantly depending on the type of AAA intervention (open surgery vs. the various subtypes of endovascular repair). Current knowledge regarding AAA in the general population may not be always applicable to CKD patients, as they have a high prevalence of co-morbid conditions and an elevated risk for periprocedural complications. This summary of a Kidney Disease: Improving Global Outcomes Controversies Conference group discussion reviews the epidemiology, pathophysiology, diagnosis, and treatment of Diseases of the Aorta in CKD and identifies knowledge gaps, areas of controversy, and priorities for future research.

Published
2022

33. MIGRAINE HEADACHE IN PATIENTS WITH SPONTANEOUS CORONARY ARTERY DISSECTION: A REPORT OF THE ISCAD REGISTRY

Author

Wells, Bryan J., primary, Wood, Malissa J., additional, Grodzinsky, Anna, additional, Gornik, Heather L., additional, Kadian-Dodov, Daniella, additional, Taylor, Angela M., additional, Hess, Connie Ng, additional, Lewey, Jennifer, additional, Henkin, Stanislav, additional, Wells, Gretchen L., additional, Tam, Lori, additional, Vitarello, Clara, additional, Alkhalfan, Fahad, additional, Chi, Gerald, additional, Gibson, C. Michael, additional, Leon, Katherine, additional, Naderi, Sahar, additional, and Kim, Soo Hyun, additional

Published
2022
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34. EXTRACORONARY VASCULAR ABNORMALITIES IN PATIENTS WITH SPONTANEOUS CORONARY ARTERY DISSECTION: A REPORT OF THE ISCAD REGISTRY

Author

Kim, Soo Hyun, primary, Wood, Malissa J., additional, Grodzinsky, Anna, additional, Gornik, Heather L., additional, Wells, Bryan J., additional, Kadian-Dodov, Daniella, additional, Sharma, Aditya M., additional, Hess, Connie Ng, additional, Lewey, Jennifer, additional, Henkin, Stanislav, additional, Wells, Gretchen L., additional, Tam, Lori, additional, Vitarello, Clara, additional, Alkhalfan, Fahad, additional, Chi, Gerald, additional, Gibson, C. Michael, additional, Leon, Katherine, additional, and Naderi, Sahar, additional

Published
2022
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35. PREVALENCE OF POTENTIAL TRIGGERS AND UNDERLYING MEDICAL CONDITIONS IN SPONTANEOUS CORONARY ARTERY DISSECTION: A REPORT OF THE ISCAD REGISTRY

Author

Kim, Soo Hyun, primary, Naderi, Sahar, additional, Grodzinsky, Anna, additional, Gornik, Heather L., additional, Wells, Bryan J., additional, Taylor, Angela, additional, Lewey, Jennifer, additional, Hess, Connie Ng, additional, Henkin, Stanislav, additional, Kadian-Dodov, Daniella, additional, Wells, Gretchen L., additional, Tam, Lori, additional, Vitarello, Clara, additional, Alkhalfan, Fahad, additional, Chi, Gerald, additional, Gibson, C. Michael, additional, Leon, Katherine, additional, and Wood, Malissa J., additional

Published
2022
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36. REPRODUCTIVE HEALTH FEATURES ASSOCIATED WITH SPONTANEOUS CORONARY ARTERY DISSECTION: A REPORT OF THE ISCAD REGISTRY

Author

Grodzinsky, Anna, primary, Kim, Esther S.H., additional, Gornik, Heather L., additional, Wells, Bryan J., additional, Taylor, Angela M., additional, Lewey, Jennifer, additional, Hess, Connie Ng, additional, Henkin, Stanislav, additional, Kadian-Dodov, Daniella, additional, Wells, Gretchen L., additional, Tam, Lori, additional, Vitarello, Clara, additional, Alkhalfan, Fahad, additional, Chi, Gerald, additional, Gibson, Michael, additional, Leon, Katherine, additional, Naderi, Sahar, additional, and Wood, Malissa, additional

Published
2022
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37. Diseases of the Aorta and Kidney Disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Sarafidis, Pantelis, Martens, Sven, Saratzis, Athanasios, Kadian-Dodov, Daniella, Murray, Patrick T, Shanahan, Catherine M, Hamdan, Allen D, Engelman, Daniel T, Teichgräber, Ulf, Herzog, Charles A, Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C, Reinecke, Holger, Johansen, Kirsten, for Conference Participants, UCL - SSS/IREC/NEFR - Pôle de Néphrologie, and UCL - (SLuc) Service de néphrologie

Subjects
medicine.medical_specialty, Physiology, Population, Aortic dissection, Renal function, urologic and male genital diseases, Kidney, Aortic diseases, Risk Factors, Physiology (medical), Chronic kidney disease, Epidemiology, medicine, Humans, Risk factor, Renal Insufficiency, Chronic, Intensive care medicine, education, Aorta, education.field_of_study, business.industry, Endovascular Procedures, Acute kidney injury, Acute Kidney Injury, medicine.disease, Abdominal aortic aneurysm, Treatment Outcome, cardiovascular system, Cardiology and Cardiovascular Medicine, business, Kidney disease, Aortic Aneurysm, Abdominal
Abstract

Chronic kidney disease (CKD) is an independent risk factor for the development of abdominal aortic aneurysm (AAA), as well as for cardiovascular and renal events and all-cause mortality following surgery for AAA or thoracic aortic dissection. In addition, the incidence of acute kidney injury (AKI) after any aortic surgery is particularly high, and this AKI per se is independently associated with future cardiovascular events and mortality. On the other hand, both development of AKI after surgery and the long-term evolution of kidney function differ significantly depending on the type of AAA intervention (open surgery vs. the various subtypes of endovascular repair). Current knowledge regarding AAA in the general population may not be always applicable to CKD patients, as they have a high prevalence of co-morbid conditions and an elevated risk for periprocedural complications. This summary of a Kidney Disease: Improving Global Outcomes Controversies Conference group discussion reviews the epidemiology, pathophysiology, diagnosis, and treatment of Diseases of the Aorta in CKD and identifies knowledge gaps, areas of controversy, and priorities for future research.

Published
2022

41. Central and peripheral arterial diseases in chronic kidney disease: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference

Author

Johansen, Kirsten L., primary, Garimella, Pranav S., additional, Hicks, Caitlin W., additional, Kalra, Philip A., additional, Kelly, Dearbhla M., additional, Martens, Sven, additional, Matsushita, Kunihiro, additional, Sarafidis, Pantelis, additional, Sood, Manish M., additional, Herzog, Charles A., additional, Cheung, Michael, additional, Jadoul, Michel, additional, Winkelmayer, Wolfgang C., additional, Reinecke, Holger, additional, Ademi, Zanfina, additional, Chang, Tara I., additional, Clark, Tim, additional, Cooper, Chris, additional, Criqui, Michael, additional, de Bhailis, Áine, additional, De Carlo, Marco, additional, Döhner, Wolfram, additional, Engelman, Daniel T., additional, Fowkes, Gerry, additional, Green, Darren, additional, Hamdan, Allen, additional, Heiss, Christian, additional, Huppert, Peter, additional, Kadian-Dodov, Daniella, additional, Lip, Gregory Y.H., additional, Małyszko, Jolanta, additional, Mark, Patrick B., additional, Miglinas, Marius, additional, Murray, Patrick, additional, Reid, Chris, additional, Rochon, Paul, additional, Ruturi, Josiah, additional, Saratzis, Athanasios, additional, Sarnak, Mark J., additional, Shanahan, Cathy M., additional, Solá, Laura, additional, Teichgräber, Ulf, additional, Textor, Stephen C., additional, Toyoda, Kazunori, additional, Yee-Moon Wang, Angela, additional, and Wong, Chris X., additional

Published
2021
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43. Diseases of the Aorta and Kidney Disease: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference.

Author

UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, Sarafidis, Pantelis, Martens, Sven, Saratzis, Athanasios, Kadian-Dodov, Daniella, Murray, Patrick T, Shanahan, Catherine M, Hamdan, Allen D, Engelman, Daniel T, Teichgräber, Ulf, Herzog, Charles A, Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C, Reinecke, Holger, Johansen, Kirsten, for Conference Participants, UCL - SSS/IREC/NEFR - Pôle de Néphrologie, UCL - (SLuc) Service de néphrologie, Sarafidis, Pantelis, Martens, Sven, Saratzis, Athanasios, Kadian-Dodov, Daniella, Murray, Patrick T, Shanahan, Catherine M, Hamdan, Allen D, Engelman, Daniel T, Teichgräber, Ulf, Herzog, Charles A, Cheung, Michael, Jadoul, Michel, Winkelmayer, Wolfgang C, Reinecke, Holger, Johansen, Kirsten, and for Conference Participants

Abstract

Chronic kidney disease (CKD) is an independent risk factor for the development of abdominal aortic aneurysm (AAA), as well as for cardiovascular and renal events and all-cause mortality following surgery for AAA or thoracic aortic dissection. In addition, the incidence of acute kidney injury (AKI) after any aortic surgery is particularly high, and this AKI per se is independently associated with future cardiovascular events and mortality. On the other hand, both development of AKI after surgery and the long-term evolution of kidney function differ significantly depending on the type of AAA intervention (open surgery versus the various subtypes of endovascular repair). Current knowledge regarding AAA in the general population may not be always applicable to CKD patients, as they have a high prevalence of co-morbid conditions and elevated risk for periprocedural complications. This summary of a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference group discussion reviews the epidemiology, pathophysiology, diagnosis, and treatment of Diseases of the Aorta in CKD and identifies knowledge gaps, areas of controversy, and priorities for future research.

Published
2021

44. Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases.

Author

UCL - SSS/DDUV/GEHU - Génétique, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Département cardiovasculaire, Georges, Adrien, Yang, Min-Lee, Berrandou, Takiy-Eddine, Bakker, Mark K, Dikilitas, Ozan, Kiando, Soto Romuald, Ma, Lijiang, Satterfield, Benjamin A, Sengupta, Sebanti, Yu, Mengyao, Deleuze, Jean-François, Dupré, Delia, Hunker, Kristina L, Kyryachenko, Sergiy, Liu, Lu, Sayoud-Sadeg, Ines, Amar, Laurence, Brummett, Chad M, Coleman, Dawn M, d'Escamard, Valentina, de Leeuw, Peter, Fendrikova-Mahlay, Natalia, Kadian-Dodov, Daniella, Li, Jun Z, Lorthioir, Aurélien, Pappaccogli, Marco, Prejbisz, Aleksander, Smigielski, Witold, Stanley, James C, Zawistowski, Matthew, Zhou, Xiang, Zöllner, Sebastian, FEIRI investigators, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group, MEGASTROKE, Amouyel, Philippe, De Buyzere, Marc L, Debette, Stéphanie, Dobrowolski, Piotr, Drygas, Wojciech, Gornik, Heather L, Olin, Jeffrey W, Piwonski, Jerzy, Rietzschel, Ernst R, Ruigrok, Ynte M, Vikkula, Miikka, Warchol Celinska, Ewa, Januszewicz, Andrzej, Kullo, Iftikhar J, Azizi, Michel, Jeunemaitre, Xavier, Persu, Alexandre, Kovacic, Jason C, Ganesh, Santhi K, Bouatia-Naji, Nabila, UCL - SSS/DDUV/GEHU - Génétique, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Département cardiovasculaire, Georges, Adrien, Yang, Min-Lee, Berrandou, Takiy-Eddine, Bakker, Mark K, Dikilitas, Ozan, Kiando, Soto Romuald, Ma, Lijiang, Satterfield, Benjamin A, Sengupta, Sebanti, Yu, Mengyao, Deleuze, Jean-François, Dupré, Delia, Hunker, Kristina L, Kyryachenko, Sergiy, Liu, Lu, Sayoud-Sadeg, Ines, Amar, Laurence, Brummett, Chad M, Coleman, Dawn M, d'Escamard, Valentina, de Leeuw, Peter, Fendrikova-Mahlay, Natalia, Kadian-Dodov, Daniella, Li, Jun Z, Lorthioir, Aurélien, Pappaccogli, Marco, Prejbisz, Aleksander, Smigielski, Witold, Stanley, James C, Zawistowski, Matthew, Zhou, Xiang, Zöllner, Sebastian, FEIRI investigators, International Stroke Genetics Consortium (ISGC) Intracranial Aneurysm Working Group, MEGASTROKE, Amouyel, Philippe, De Buyzere, Marc L, Debette, Stéphanie, Dobrowolski, Piotr, Drygas, Wojciech, Gornik, Heather L, Olin, Jeffrey W, Piwonski, Jerzy, Rietzschel, Ernst R, Ruigrok, Ynte M, Vikkula, Miikka, Warchol Celinska, Ewa, Januszewicz, Andrzej, Kullo, Iftikhar J, Azizi, Michel, Jeunemaitre, Xavier, Persu, Alexandre, Kovacic, Jason C, Ganesh, Santhi K, and Bouatia-Naji, Nabila

Abstract

Fibromuscular dysplasia (FMD) is an arteriopathy associated with hypertension, stroke and myocardial infarction, affecting mostly women. We report results from the first genome-wide association meta-analysis of six studies including 1556 FMD cases and 7100 controls. We find an estimate of SNP-based heritability compatible with FMD having a polygenic basis, and report four robustly associated loci (PHACTR1, LRP1, ATP2B1, and LIMA1). Transcriptome-wide association analysis in arteries identifies one additional locus (SLC24A3). We characterize open chromatin in arterial primary cells and find that FMD associated variants are located in arterial-specific regulatory elements. Target genes are broadly involved in mechanisms related to actin cytoskeleton and intracellular calcium homeostasis, central to vascular contraction. We find significant genetic overlap between FMD and more common cardiovascular diseases and traits including blood pressure, migraine, intracranial aneurysm, and coronary artery disease.

Published
2021

48. Rare loss-of-function mutations of PTGIR are enriched in fibromuscular dysplasia

Author

Georges, Adrien, primary, Albuisson, Juliette, additional, Berrandou, Takiy, additional, Dupré, Délia, additional, Lorthioir, Aurélien, additional, D’Escamard, Valentina, additional, Di Narzo, Antonio F, additional, Kadian-Dodov, Daniella, additional, Olin, Jeffrey W, additional, Warchol-Celinska, Ewa, additional, Prejbisz, Aleksander, additional, Januszewicz, Andrzej, additional, Bruneval, Patrick, additional, Baranowska, Anna A, additional, Webb, Tom R, additional, Hamby, Stephen E, additional, Samani, Nilesh J, additional, Adlam, David, additional, Fendrikova-Mahlay, Natalia, additional, Hazen, Stanley, additional, Wang, Yu, additional, Yang, Min-Lee, additional, Hunker, Kristina, additional, Combaret, Nicolas, additional, Motreff, Pascal, additional, Chédid, Antoine, additional, Fiquet, Béatrice, additional, Plouin, Pierre-François, additional, Mousseaux, Elie, additional, Azarine, Arshid, additional, Amar, Laurence, additional, Azizi, Michel, additional, Gornik, Heather L, additional, Ganesh, Santhi K, additional, Kovacic, Jason C, additional, Jeunemaitre, Xavier, additional, and Bouatia-Naji, Nabila, additional

Published
2020
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49. Supplemental_Table_1_-_rev – Supplemental material for First International Consensus on the diagnosis and management of fibromuscular dysplasia

Author

Heather L Gornik (Co-Chair), Alexandre Persu (Co-Chair), Adlam, David, Aparicio, Lucas S, Azizi, Michel, Boulanger, Marion, Bruno, Rosa Maria, Leeuw, Peter De, Fendrikova-Mahlay, Natalia, Froehlich, James, Santhi K Ganesh, Gray, Bruce H, Cathlin Jamison, Januszewicz, Andrzej, Jeunemaitre, Xavier, Kadian-Dodov, Daniella, Kim, Esther SH, Kovacic, Jason C, Mace, Pamela, Morganti, Alberto, Sharma, Aditya, Southerland, Andrew M, Touzé, Emmanuel, Niepen, Patricia Van Der, Jiguang Wang, Weinberg, Ido, Wilson, Scott, Olin, Jeffrey W, and Pierre-Francois Plouin

Subjects
FOS: Clinical medicine, Cardiology, 110323 Surgery
Abstract

Supplemental material, Supplemental_Table_1_-_rev for First International Consensus on the diagnosis and management of fibromuscular dysplasia by Heather L Gornik (Co-Chair), Alexandre Persu (Co-Chair), David Adlam, Lucas S Aparicio, Michel Azizi, Marion Boulanger, Rosa Maria Bruno, Peter de Leeuw, Natalia Fendrikova-Mahlay, James Froehlich, Santhi K Ganesh, Bruce H Gray, Cathlin Jamison, Andrzej Januszewicz, Xavier Jeunemaitre, Daniella Kadian-Dodov, Esther SH Kim, Jason C Kovacic, Pamela Mace, Alberto Morganti, Aditya Sharma, Andrew M Southerland, Emmanuel Touzé, Patricia van der Niepen, Jiguang Wang, Ido Weinberg, Scott Wilson, Jeffrey W Olin and Pierre-Francois Plouin in Vascular Medicine

Published
2019
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50. Supplemental_Impact_of_FMD_on_QoL_and_role_of_patient_assoc_final – Supplemental material for First International Consensus on the diagnosis and management of fibromuscular dysplasia

Author

Heather L Gornik (Co-Chair), Alexandre Persu (Co-Chair), Adlam, David, Aparicio, Lucas S, Azizi, Michel, Boulanger, Marion, Bruno, Rosa Maria, Leeuw, Peter De, Fendrikova-Mahlay, Natalia, Froehlich, James, Santhi K Ganesh, Gray, Bruce H, Cathlin Jamison, Januszewicz, Andrzej, Jeunemaitre, Xavier, Kadian-Dodov, Daniella, Kim, Esther SH, Kovacic, Jason C, Mace, Pamela, Morganti, Alberto, Sharma, Aditya, Southerland, Andrew M, Touzé, Emmanuel, Niepen, Patricia Van Der, Jiguang Wang, Weinberg, Ido, Wilson, Scott, Olin, Jeffrey W, and Pierre-Francois Plouin

Subjects
FOS: Clinical medicine, Cardiology, 110323 Surgery
Abstract

Supplemental material, Supplemental_Impact_of_FMD_on_QoL_and_role_of_patient_assoc_final for First International Consensus on the diagnosis and management of fibromuscular dysplasia by Heather L Gornik (Co-Chair), Alexandre Persu (Co-Chair), David Adlam, Lucas S Aparicio, Michel Azizi, Marion Boulanger, Rosa Maria Bruno, Peter de Leeuw, Natalia Fendrikova-Mahlay, James Froehlich, Santhi K Ganesh, Bruce H Gray, Cathlin Jamison, Andrzej Januszewicz, Xavier Jeunemaitre, Daniella Kadian-Dodov, Esther SH Kim, Jason C Kovacic, Pamela Mace, Alberto Morganti, Aditya Sharma, Andrew M Southerland, Emmanuel Touzé, Patricia van der Niepen, Jiguang Wang, Ido Weinberg, Scott Wilson, Jeffrey W Olin and Pierre-Francois Plouin in Vascular Medicine

Published
2019
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