Search

Your search keyword '"KOIKE, Teruhiko"' showing total 309 results
Start Over Author "KOIKE, Teruhiko"
309 results on '"KOIKE, Teruhiko"'

14. Related factors of trunk intramuscular adipose tissue content in younger and older men

Author

KITAGAWA, Funa, OGAWA, Madoka, YOSHIKO, Akito, OSHIDA, Yoshiharu, KOIKE, Teruhiko, AKIMA, Hiroshi, and TANAKA, Noriko

Abstract

The purpose of this study was to investigate the factors relate to trunk intramuscular fat content in younger and older men. Healthy 23 younger (20 to 29 years) and 20 older men (63 to 79 years) participated in this study. The trunk intramuscular fat content was measured using magnetic resonance imaging at the level of 3rd lumbar vertebra. Blood properties and physical performances were also measured. Dietary intake was assessed with a selfadministered diet history questionnaire. We quantified the status of the 10 nutrients intakes by summing the number of items that met the criteria of dietary reference intakes for Japanese. As a result, trunk intramuscular fat content was significantly higher in older men compared with that of younger ones (p

Published
2022

39. Basigin deficiency prevents anaplerosis and ameliorates insulin resistance and hepatosteatosis

Author

Ryuge, Akihiro, primary, Kosugi, Tomoki, additional, Maeda, Kayaho, additional, Banno, Ryoichi, additional, Gou, Yang, additional, Zaitsu, Kei, additional, Ito, Takanori, additional, Sato, Yuka, additional, Hirayama, Akiyoshi, additional, Tsubota, Shoma, additional, Honda, Takashi, additional, Nakajima, Kazuki, additional, Ozaki, Tomoya, additional, Kondoh, Kunio, additional, Takahashi, Kazuo, additional, Kato, Noritoshi, additional, Ishimoto, Takuji, additional, Soga, Tomoyoshi, additional, Nakagawa, Takahiko, additional, Koike, Teruhiko, additional, Arima, Hiroshi, additional, Yuzawa, Yukio, additional, Minokoshi, Yasuhiko, additional, Maruyama, Shoichi, additional, and Kadomatsu, Kenji, additional

Published
2021
Full Text
View/download PDF

47. The characteristics of muscle quantity, quality and physical functions in elderly with long-term care

Author

YOSHIKO, Akito, KAJI, Takashi, SUGIYAMA, Hiroki, KOIKE, Teruhiko, OSHIDA, Yoshiharu, and AKIMA, Hiroshi

Abstract

The purpose of this study was to investigate the characteristics of muscle quantity, quality and physical functions in elderly with long-term care. Twenty-four elderly with long-term care (LTC-group, age 78 ± 8 years) and 21 elderly without long-term care (Cont-group, age 72 ± 7 years) participated in this study. Skeletal muscle mass (kg) was measured by a bioelectrical impedance device, and the skeletal muscle index [= skeletal muscle mass (kg) / height (m) 2] was calculated. The muscle thickness and echo intensity, as the parameters of muscle quantity and quality, was assessed from the rectus femoris and biceps femoris using B-mode transverse ultrasound images. We measured eight physical function tests [isometric knee extension peak torque, functional reach, one leg stand, sit-tostand test, 5-m normal/maximal speed walking, handgrip strength, and timed up and go test (TUG)]. Skeletal muscle index, muscle thickness and echo intensity were no difference between LTC- and Cont-group. The score of functional reach and sit-to-stand in LTC-group was lower than that in Cont-group (P < 0.001). The 5-m normal speed walking time was longer in LTC-group than Cont-group (LTC-group, 7.00 ± 2.71 s vs. Cont-group, 3.95 ± 0.48 s, P < 0.001); accordingly, the normal walk speed in LTC-group was slower than Cont-group (LTC-group, 0.81 ± 0.26 m/s vs. Cont-group, 1.28 ± 0.16 m/s, P < 0.001). Similar differences were found in the 5-m maximal speed walking time and speed. TUG score was worse in LTC-group than that in Cont-group. These results suggest that the physical functions, which indicated gait and balance abilities, lacked in LTC-group although muscle quantity and quality was similar to Cont-group. The deterioration of physical dysfunction in LTC-group was clearly shown in this study, and this could be contributed for the recovering from disability in LTC-group by rehabilitation or physical training.

Published
2018

48. Inhibited angiogenesis in aging: a role for TIMP-2

Author

Koike, Teruhiko, Vernon, Robert B., Gooden, Michel D., Sadoun, Eman, and Reed, May J.

Subjects
Aging -- Physiological aspects, Neovascularization -- Physiological aspects, Metalloenzymes -- Physiological aspects, Health, Seniors
Abstract

Factors responsible for age-associated impairment of angiogenesis are poorly understood. We observed that in aged mice, new fibrovascular tissue within subcutaneous polyvinyl alcohol sponges expressed more tissue inhibitor of metalloproteinases (TIMP)-2 than did corresponding tissue from young mice. In complementary studies in vitro, we utilized young and aged human microvascular endothelial cell lines (hmEC36 and hmEC90, respectively) and compared their morphogenetic capacity within three-dimensional collagen. HmEC90 exhibited poor formation of tubular, capillary-like structures in vitro, diminished expression of active matrix metalloproteinase (MMP)-2, and similar or lesser amounts of MT1-MMP relative to hmEC36. Correspondingly, the MMP inhibitor GM6001 decreased tubulogenesis by hmEC36 to levels observed for hmEC90. In vitro, hmEC90 expressed similar quantities of TIMP-1, but more TIMP-2 than did hmEC36. Accordingly, purified TIMP-2 inhibited tubulogenesis by hmEC36. Collectively, our studies indicate that elevated levels of TIMP-2 modulate decreased angiogenesis in aged tissues, most likely via TIMP-2-mediated inhibition of MMP-2 and MT1-MMP.

Published
2003

Catalog

Books, media, physical & digital resources
See catalog results