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618 results on '"KIMURA, Fuminori"'

1. Out-of-pocket fertility preservation expenses: data from a Japanese nationwide multicenter survey

Author

Ono, Masanori, Takai, Yasushi, Harada, Miyuki, Horie, Akihito, Dai, Yidan, Kikuchi, Eiji, Miyachi, Mitsuru, Yamamoto, Tetsuya, Fujii, Nobuharu, Kajiyama, Hiroaki, Manabe, Atsushi, Yasuoka, Toshiaki, Katsuragi, Shinji, Mekaru, Keiko, Maezawa, Tadashi, Horage, Yuki, Kataoka, Shinsuke, Nakayama, Robert, Nakajima, Takako Eguchi, Kimura, Fuminori, Shimizu, Chikako, Sugimoto, Kohei, Takae, Seido, Yumura, Yasushi, Nishi, Hirotaka, Furui, Tatsuro, Morishige, Ken-Ichirou, Watanabe, Chie, Osuga, Yutaka, and Suzuki, Nao

Published
2024
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3. The clinical trial of alternative relugolix administration for uterine leiomyoma prior to surgically treatment: a study protocol for Non-Adverse Relugolix Administration (NARA) trial

Author

Kawahara, Naoki, Kawaguchi, Ryuji, Yamamoto, Konosuke, Nishikawa, Kyohei, Matsuoka, Motoki, Maehana, Tomoka, Fukui, Yosuke, Yamanaka, Shoichiro, Sugimoto, Sumire, Iwai, Kana, Yamada, Yuki, Kurakami, Hiroyuki, Hirata, Takumi, Takashima, Ryuzo, Suzuki, Shota, Asada, Kiyoshi, Kasahara, Masato, and Kimura, Fuminori

Published
2024
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4. Effect of a web-based fertility preservation training program for medical professionals in Japan

Author

Ono, Masanori, Harada, Miyuki, Horie, Akihito, Dai, Yidan, Horiguchi, Itsuko, Kikuchi, Eiji, Kimura, Fuminori, Koizumi, Tomoe, Komeya, Mitsuru, Mizunuma, Naoki, Oseto, Kumiko, Ota, Kuniaki, Shimizu, Chikako, Sugimoto, Kohei, Takae, Seido, Takeuchi, Emi, Nishi, Hirotaka, Yumura, Yasushi, Furui, Tatsuro, Takai, Yasushi, Morishige, Ken-Ichirou, Watanabe, Chie, Osuga, Yutaka, and Suzuki, Nao

Published
2023
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8. Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 for fertility preservation in childhood, adolescent, and young adult cancer patients: part 2

Author

Tozawa, Akiko, Kimura, Fuminori, Takai, Yasushi, Nakajima, Takeshi, Ushijima, Kimio, Kobayashi, Hiroaki, Satoh, Toyomi, Harada, Miyuki, Sugimoto, Kohei, Saji, Shigehira, Shimizu, Chikako, Akiyama, Kyoko, Bando, Hiroko, Kuwahara, Akira, Furui, Tatsuro, Okada, Hiroshi, Kawai, Koji, Shinohara, Nobuo, Nagao, Koichi, Kitajima, Michio, Suenobu, Souichi, Soejima, Toshinori, Miyachi, Mitsuru, Miyoshi, Yoko, Yoneda, Akihiro, Horie, Akihito, Ishida, Yasushi, Usui, Noriko, Kanda, Yoshinobu, Fujii, Nobuharu, Endo, Makoto, Nakayama, Robert, Hoshi, Manabu, Yonemoto, Tsukasa, Kiyotani, Chikako, Okita, Natsuko, Baba, Eishi, Muto, Manabu, Kikuchi, Iwaho, Morishige, Ken-ichirou, Tsugawa, Koichiro, Nishiyama, Hiroyuki, Hosoi, Hajime, Tanimoto, Mitsune, Kawai, Akira, Sugiyama, Kazuhiko, Boku, Narikazu, Yonemura, Masato, Hayashi, Naoko, Aoki, Daisuke, Suzuki, Nao, and Osuga, Yutaka

Published
2022
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9. Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 for fertility preservation in childhood, adolescent, and young adult cancer patients: part 1

Author

Harada, Miyuki, Kimura, Fuminori, Takai, Yasushi, Nakajima, Takeshi, Ushijima, Kimio, Kobayashi, Hiroaki, Satoh, Toyomi, Tozawa, Akiko, Sugimoto, Kohei, Saji, Shigehira, Shimizu, Chikako, Akiyama, Kyoko, Bando, Hiroko, Kuwahara, Akira, Furui, Tatsuro, Okada, Hiroshi, Kawai, Koji, Shinohara, Nobuo, Nagao, Koichi, Kitajima, Michio, Suenobu, Souichi, Soejima, Toshinori, Miyachi, Mitsuru, Miyoshi, Yoko, Yoneda, Akihiro, Horie, Akihito, Ishida, Yasushi, Usui, Noriko, Kanda, Yoshinobu, Fujii, Nobuharu, Endo, Makoto, Nakayama, Robert, Hoshi, Manabu, Yonemoto, Tsukasa, Kiyotani, Chikako, Okita, Natsuko, Baba, Eishi, Muto, Manabu, Kikuchi, Iwaho, Morishige, Ken-ichirou, Tsugawa, Koichiro, Nishiyama, Hiroyuki, Hosoi, Hajime, Tanimoto, Mitsune, Kawai, Akira, Sugiyama, Kazuhiko, Boku, Narikazu, Yonemura, Masato, Hayashi, Naoko, Aoki, Daisuke, Osuga, Yutaka, and Suzuki, Nao

Published
2022
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11. List of contributors

Author

Agcaoili-De Jesus, Maria Socorro L., primary, Alentajan-Aleta, Lara Theresa C., additional, Alsubki, Lujain, additional, Anchan, Raymond M., additional, Arck, Petra Clara, additional, Bao, Shihua, additional, Barini, Ricardo, additional, Beaman, Kenneth, additional, Bermas, Bonnie L., additional, Borodina, Elena, additional, Brodeur, Tia, additional, Cai, Songchen, additional, Cavalcante, Marcelo Borges, additional, Chen, Yuekun, additional, Clinton, Tiffany Alexis, additional, Dambaeva, Svetlana, additional, Di Simone, Nicoletta, additional, Diao, Lianghui, additional, Diener, Kerrilyn R., additional, Ding, Jinli, additional, Du, Mengyang, additional, Duero, Joseph, additional, Dzhemlikhanova, Lyailya Kh., additional, Esfandiari, Navid, additional, Fang, Xuhui, additional, Fukui, Atsushi, additional, George, Jenny S., additional, Gilman-Sachs, Alice, additional, Guzman-Genuino, Ruth Marian, additional, Gzgzyan, Alexander M., additional, Han, Ae Ra, additional, Han, Jae Won, additional, Hanada, Tetsuro, additional, Hasegawa, Akiko, additional, Izumi, Gentaro, additional, Kato, Toru, additional, Kim, Sun Kwon, additional, Kimura, Fuminori, additional, Kitazawa, Jun, additional, Koga, Kaori, additional, Kuroda, Keiji, additional, Kwak-Kim, Joanne, additional, Lansiaux, Maud, additional, Laura, Trespidi, additional, Lédée, Nathalie, additional, Lee, Si won, additional, Lee, Sung Ki, additional, Luigi, Meroni Pier, additional, Luu, Thanh, additional, Mills, Brooke, additional, Morimune, Aina, additional, Mortimer, Roisin, additional, Murakami, Takashi, additional, Nakagawa, Koji, additional, Nakamura, Akiko, additional, Niauri, Dariko A., additional, Ocampo-Cervantes, Cherie C., additional, Osuga, Yutaka, additional, Otadoy-Agustin, Jenifer R., additional, Park, Joon Cheol, additional, Roberta, Erra, additional, Saeki, Shinichiro, additional, Shibahara, Hiroaki, additional, Shoenfeld, Yehuda, additional, Sugiyama, Rikikazu, additional, Takeyama, Ryu, additional, Tal, Reshef, additional, Tersigni, Chiara, additional, Thiele, Kristin, additional, Vaucoret, Virginie, additional, Wakimoto, Yu, additional, Wally, Ossola, additional, Wang, Xiao, additional, Wang, Yanshi, additional, Wei, Yiqiu, additional, Wöhrle, Ronja, additional, Wolf, Katharine, additional, Wu, Li, additional, Yamaya, Ayano, additional, Yin, Tailang, additional, and Zeng, Yong, additional

Published
2022
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13. Correction to: Japan Society of Clinical Oncology Clinical Practice Guidelines 2017 for fertility preservation in childhood, adolescent, and young adult cancer patients: part 2

Author

Tozawa, Akiko, Kimura, Fuminori, Takai, Yasushi, Nakajima, Takeshi, Ushijima, Kimio, Kobayashi, Hiroaki, Satoh, Toyomi, Harada, Miyuki, Sugimoto, Kohei, Saji, Shigehira, Shimizu, Chikako, Akiyama, Kyoko, Bando, Hiroko, Kuwahara, Akira, Furui, Tatsuro, Okada, Hiroshi, Kawai, Koji, Shinohara, Nobuo, Nagao, Koichi, Kitajima, Michio, Suenobu, Souichi, Soejima, Toshinori, Miyachi, Mitsuru, Miyoshi, Yoko, Yoneda, Akihiro, Horie, Akihito, Ishida, Yasushi, Usui, Noriko, Kanda, Yoshinobu, Fujii, Nobuharu, Endo, Makoto, Nakayama, Robert, Hoshi, Manabu, Yonemoto, Tsukasa, Kiyotani, Chikako, Okita, Natsuko, Baba, Eishi, Muto, Manabu, Kikuchi, Iwaho, Morishige, Ken-ichirou, Tsugawa, Koichiro, Nishiyama, Hiroyuki, Hosoi, Hajime, Tanimoto, Mitsune, Kawai, Akira, Sugiyama, Kazuhiko, Boku, Narikazu, Yonemura, Masato, Hayashi, Naoko, Aoki, Daisuke, Suzuki, Nao, and Osuga, Yutaka

Published
2022
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14. Clinical implications of genetic testing for congenital protein C deficiency in pregnancy.

Author

Maehana, Tomoka, Nishikubo, Toshiya, Maekawa, Ryo, Hotta, Taeko, Nishikawa, Kyohei, Waki, Keita, Makino, Yuko, Akasaka, Juria, Kawaguchi, Ryuji, and Kimura, Fuminori

Subjects
BLOOD protein disorder diagnosis, ANTICOAGULANTS, VENA cava inferior, VENOUS thrombosis, BLOOD protein disorders, PRENATAL diagnosis, GENETIC counseling, SURGICAL instruments, GENETIC mutation, GENETIC testing, FETUS, PREGNANCY
Abstract

Congenital protein C (PC) deficiency is a mostly autosomal dominant hereditary thrombophilia associated with early onset arterial and venous thrombotic diseases. In newborns, PC deficiency results in severe complications such as cerebral hemorrhage, cerebral infarction, and purpura fulminans, leading to death in some cases. We report two cases of deep vein thrombosis diagnosed during pregnancy that prompted genetic testing confirming definitive congenital PC deficiency. One patient with deep vein thrombosis at 30 weeks of gestation underwent anticoagulation therapy with the placement of an inferior vena cava filter. Genetic testing revealed a missense mutation in the PC gene. Another patient developed deep vein thrombosis at 9 weeks of gestation and received anticoagulant therapy, revealing a frameshift mutation in the gene. Genetic testing confirming congenital PC deficiency facilitates tailored postpartum management, including long‐term anticoagulation therapy, based on the mother's thrombosis risk. For newborns, early diagnosis allows timely preparation of treatments, such as freshly thawed frozen plasma or PC replacement therapy and ensures closer monitoring through imaging evaluations, enabling early intervention to decrease the severity of potential complications. Given its utility in managing maternal and neonatal outcomes, early genetic testing in suspected cases of maternal PC deficiency is crucial before delivery. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Phenotypes and clinical laboratory data for polycystic ovary syndrome cases: A nationwide survey in Japan.

Author

Noguchi, Hiroki, Iwasa, Takeshi, Iwase, Akira, Kanasaki, Haruhiko, Kimura, Fuminori, Kugu, Koji, Saito, Kazuki, Baba, Tsuyoshi, Hara, Tetsuaki, and Matsuzaki, Toshiya

Subjects
OBESITY genetics, RISK assessment, TESTOSTERONE, BODY mass index, HYPERTRICHOSIS, T-test (Statistics), DATA analysis, RESEARCH funding, QUESTIONNAIRES, HYPERANDROGENISM, BLOOD collection, KRUSKAL-Wallis Test, POLYCYSTIC ovary syndrome, DESCRIPTIVE statistics, MANN Whitney U Test, CLINICAL pathology, SURVEYS, LUTEINIZING hormone, FOLLICLE-stimulating hormone, STATISTICS, COMPARATIVE studies, MENSTRUATION disorders, DATA analysis software, OBESITY, PHENOTYPES, AMENORRHEA, DISEASE incidence, DISEASE risk factors
Abstract

Aim: Describe the current phenotypes and clinical laboratory data regarding polycystic ovary syndrome (PCOS) in Japan, taking into account ethnic differences and obesity status. Methods: Data for 986 PCOS cases and 965 control cases were collected using a nationwide survey in Japan. Obese/overweight (body mass index [BMI] ≥25 kg/m2) and non‐obese/overweight (BMI <25 kg/m2) cases were compared. Results: Japanese PCOS cases predominantly involved non‐obese/overweight patients, accounting for 75% of all cases. Among non‐obese/overweight PCOS cases, the incidence of both amenorrhea and clinical/biochemical hyperandrogenism was significantly lower than in obese/overweight PCOS cases, whereas the rate of elevated serum luteinizing hormone (LH) level was significantly higher. Even though the incidence of hirsutism in Japan is only 13.5%, the detection rate for hyperandrogenism increased by as much as 30.4% when hirsutism was added to the Japan Society of Obstetrics and Gynecology (JSOG) criteria for the diagnosis of hyperandrogenism in addition to elevated serum total testosterone level. When evaluated based on timing of blood sampling, the LH level and LH/follicle‐stimulating hormone ratio determined at the initial consultation involving a chief complaint of irregular menstrual cycle (after confirming the absence of follicles measuring ≥1 cm in diameter) were significantly higher than on days 2–3 or 4–6 of the menstrual cycle. Conclusions: Ethnic differences, including obesity status, affected the phenotype and clinical laboratory data of Japanese PCOS patients, such as the incidence rates of clinical/biochemical hyperandrogenism and the rate of elevated basal LH level. Adding hirsutism to the JSOG 2024 criteria would enhance the accuracy of PCOS diagnosis and enhance consistency with the Rotterdam 2003 criteria. Measuring basal LH level is useful for assessing the endocrinologic characteristics of Japanese PCOS cases, as well as lean Asian PCOS cases, but the timing of blood sampling can affect the result. [ABSTRACT FROM AUTHOR]

Published
2024
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17. MR Relaxometry for Discriminating Malignant Ovarian Cystic Tumors: A Prospective Multicenter Cohort Study

Author

Kawahara, Naoki, primary, Kobayashi, Hiroshi, additional, Maehana, Tomoka, additional, Iwai, Kana, additional, Yamada, Yuki, additional, Kawaguchi, Ryuji, additional, Takahama, Junko, additional, Marugami, Nagaaki, additional, Nishi, Hirotaka, additional, Sakai, Yosuke, additional, Takano, Hirokuni, additional, Seki, Toshiyuki, additional, Yokosu, Kota, additional, Hirata, Yukihiro, additional, Yoshida, Koyo, additional, Ujihira, Takafumi, additional, and Kimura, Fuminori, additional

Published
2024
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19. Visible and near‑infrared interactance spectroscopy is a non‑invasive technique which can be used to evaluate the hemoglobin concentration in endometriotic cyst fluid

Author

Imanaka, Shogo, Kimura, Fuminori, Kobayashi, Hiroshi, Imanaka, Shogo, Kimura, Fuminori, and Kobayashi, Hiroshi

Abstract

Hemoglobin concentrations in endometriotic cyst fluids have been found to be associated with distinct clinical manifestations, such as pelvic pain and infertility, as well as with malignant transformation. However, the measurement of the hemoglobin concentration in cyst fluid is an invasive procedure. The present study aimed to evaluate the usefulness of visible and near‑infrared interactance spectroscopy as a non‑invasive technique for estimating the hemoglobin concentration in endometriotic cystic fluid. Optical fibers were directly placed onto sliced raw pork (up to 10‑mm‑thick as an anatomical barrier on the cyst's surface) that covers a cuvette containing hemoglobin solution or endometriotic cyst fluid. Partial least square regression based on the second derivative using visible and near‑infrared interactance spectroscopy (wavelength region, 500‑1,200 nm) was used to estimate the hemoglobin concentration. The samples were categorized into the evaluation sets (i.e., calibration set) to create calibration curves and test sets (i.e., validation set) to validate equations. The cyst fluid at 5 mm of pork thickness achieved a high correlation between actual and predicted hemoglobin concentrations (calibration (R2=0.977) and validation (R2=0.874) data). However, the correlation slightly decreased at 10‑mm pork thickness (i.e., calibration (R2=0.979) and validation (R2=0.580) data). Interactance spectroscopy may thus be a non‑invasive tool which can be used to estimate the hemoglobin concentration in endometriotic cyst fluid when the anatomical barrier is 5 mm. This technology is a reliable modality for predicting the severity of dysmenorrhea and infertility, as well as malignant transformation, in a number of patients with endometriotic cysts. Such quantitative optical spectroscopic imaging technologies may enable the accurate diagnosis of the pathological processes in endometriotic cysts in clinical practice.

Published
2024

33. The clinical trial of alternative Relugolix administration for uterine leiomyoma prior to surgically treatment: a study protocol for Non-Adverse Relugolix Administration (NARA) trial

Author

Kawahara, Naoki, primary, Kawaguchi, Ryuji, additional, Yamamoto, Konosuke, additional, Nishikawa, Kyohei, additional, Matsuoka, Motoki, additional, Maehana, Tomoka, additional, Fukui, Yosuke, additional, Yamanaka, Shoichiro, additional, Sugimoto, Sumire, additional, Iwai, Kana, additional, Yamada, Yuki, additional, Kurakami, Hiroyuki, additional, Hirata, Takumi, additional, Takashima, Ryuzo, additional, Suzuki, Shota, additional, Asada, Kiyoshi, additional, Kasahara, Masato, additional, and Kimura, Fuminori, additional

Published
2023
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40. The Comparison of Three Predictive Indexes to Discriminate Malignant Ovarian Tumors from Benign Ovarian Endometrioma: The Characteristics and Efficacy

Author

Yamanaka, Shoichiro, Kawahara, Naoki, Kawaguchi, Ryuji, Waki, Keita, Maehana, Tomoka, Fukui, Yosuke, Miyake, Ryuta, Yamada, Yuki, Kobayashi, Hiroshi, Kimura, Fuminori, Yamanaka, Shoichiro, Kawahara, Naoki, Kawaguchi, Ryuji, Waki, Keita, Maehana, Tomoka, Fukui, Yosuke, Miyake, Ryuta, Yamada, Yuki, Kobayashi, Hiroshi, and Kimura, Fuminori

Abstract

This study aimed to evaluate the prediction efficacy of malignant transformation of ovarian endometrioma (OE) using the Copenhagen Index (CPH-I), the risk of ovarian malignancy algorithm (ROMA), and the R2 predictive index. This retrospective study was conducted at the Department of Gynecology, Nara Medical University Hospital, from January 2008 to July 2021. A total of 171 patients were included in the study. In the current study, cases were divided into three cohorts: pre-menopausal, post-menopausal, and a combined cohort. Patients with benign ovarian tumor mainly received laparoscopic surgery, and patients with suspected malignant tumors underwent laparotomy. Information from a review chart of the patients’ medical records was collected. In the combined cohort, a multivariate analysis confirmed that the ROMA index, the R2 predictive index, and tumor laterality were extracted as independent factors for predicting malignant tumors (hazard ratio (HR): 222.14, 95% confidence interval (CI): 22.27–2215.50, p < 0.001; HR: 9.80, 95% CI: 2.90–33.13, p < 0.001; HR: 0.15, 95% CI: 0.03–0.75, p = 0.021, respectively). In the pre-menopausal cohort, a multivariate analysis confirmed that the CPH index and the R2 predictive index were extracted as independent factors for predicting malignant tumors (HR: 6.45, 95% CI: 1.47–28.22, p = 0.013; HR: 31.19, 95% CI: 8.48–114.74, p < 0.001, respectively). Moreover, the R2 predictive index was only extracted as an independent factor for predicting borderline tumors (HR: 45.00, 95% CI: 7.43–272.52, p < 0.001) in the combined cohort. In pre-menopausal cases or borderline cases, the R2 predictive index is useful; while, in post-menopausal cases, the ROMA index is better than the other indexes., © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Published
2023

42. Topic Model for User Reviews with Adaptive Windows

Author

Konishi, Takuya, Kimura, Fuminori, Maeda, Akira, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Serdyukov, Pavel, editor, Braslavski, Pavel, editor, Kuznetsov, Sergei O., editor, Kamps, Jaap, editor, Rüger, Stefan, editor, Agichtein, Eugene, editor, Segalovich, Ilya, editor, and Yilmaz, Emine, editor

Published
2013
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43. Word Segmentation for Text in Japanese Ancient Writings Based on Probability of Character N-Grams

Author

Yoshimura, Mamoru, Kimura, Fuminori, Maeda, Akira, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Chen, Hsin-Hsi, editor, and Chowdhury, Gobinda, editor

Published
2012
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44. Visualization of Relationships among Historical Persons Using Locational Information

Author

Osaki, Takahiko, Itsubo, Sho, Kimura, Fuminori, Tezuka, Taro, Maeda, Akira, Hutchison, David, Series editor, Kanade, Takeo, Series editor, Kittler, Josef, Series editor, Kleinberg, Jon M., Series editor, Mattern, Friedemann, Series editor, Mitchell, John C., Series editor, Naor, Moni, Series editor, Nierstrasz, Oscar, Series editor, Pandu Rangan, C., Series editor, Steffen, Bernhard, Series editor, Sudan, Madhu, Series editor, Terzopoulos, Demetri, Series editor, Tygar, Doug, Series editor, Vardi, Moshe Y., Series editor, Weikum, Gerhard, Series editor, Tanaka, Katsumi, editor, Fröhlich, Peter, editor, and Kim, Kyoung-Sook, editor

Published
2011
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47. Approach to Cross-Language Retrieval for Japanese Traditional Fine Art: Ukiyo-e Database

Author

Batjargal, Biligsaikhan, Kimura, Fuminori, Maeda, Akira, Hutchison, David, editor, Kanade, Takeo, editor, Kittler, Josef, editor, Kleinberg, Jon M., editor, Mattern, Friedemann, editor, Mitchell, John C., editor, Naor, Moni, editor, Nierstrasz, Oscar, editor, Pandu Rangan, C., editor, Steffen, Bernhard, editor, Sudan, Madhu, editor, Terzopoulos, Demetri, editor, Tygar, Doug, editor, Vardi, Moshe Y., editor, Weikum, Gerhard, editor, Lalmas, Mounia, editor, Jose, Joemon, editor, Rauber, Andreas, editor, Sebastiani, Fabrizio, editor, and Frommholz, Ingo, editor

Published
2010
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