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Objectives: To evaluate the correlation between stroke volume variation (SVV) and inferior vena cava distensibility index (dIVC) as a marker for fluid responsiveness in mechanically ventilated hypotensive intensive care unit (ICU) patients.Methodology and Design: This study is designed as prospective observational study conducted in patients admitted to an ICU who were mechanically ventilated and experienced a hypotensive episode.Intervention: A fluid challenge of 10 mL/kg ringer's lactate was given over 20 min.Measurements: Hemodynamic parameters as well as SVV, IVCmax, IVCmin, dIVC, and cardiac output (CO), were recorded at a different time interval. An increase in ≥15% of CO was taken as fluid responsiveness.Results: Out of 67 patients, 67.2% responded to fluid challenge. Pearson's correlation graph at baseline showed a strong positive correlation between dIVC and SVV with r = 0.453, (P < 0.002). Non-responders also had a strong positive correlation (r = 0.474) at the baseline. Bland Altman's analysis of the correlation between dIVC and SVV post-fluid challenge showed a mean difference of - 4.444, with 1.49% of the values falling outside the limits of agreement (18.418 and -27.306). This difference was clinically significant. Pearson's correlation graph post-fluid challenge showed a moderately strong positive correlation between dIVC and SVV with r = 0.298 and P value = 0.047, which was statistically significant. Also, non-responders had a weak correlation as compared to the responder's group, r = 0.364 and P value = 0.095, which was not clinically significant. There was no significant difference in the trend of dIVC and SVV values between the non-surgical and surgical groups, nor was there any gender difference analyzed in the study.Conclusion: This study ascertains the positive correlation between dIVC and SVV and justifies its use in a clinical setting of hypotension suspected to be due to hypovolemia. [ABSTRACT FROM AUTHOR]

The 20-G iv cannula was flushed with heparin and left radial artery was now again cannulated. After taking all sterile precautions, right radial artery was palpated with nondominant hand, 1-2 cm proximal to the wrist, and a 20-G intravenous (iv) cannula was used to prick the artery. After seeing the flash of blood in the hub, needle was removed and the catheter was advanced in the artery. [Extracted from the article]

Competing Interests: There are no conflicts of interest.