70 results on '"K. Ennabli"'
Search Results
2. Chirurgie de l’endocardite sur valves natives à la phase active
- Author
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A. Tarmiz, M. Beltaïfa, M.S. Fradi, F. Limayem, S. Mlika, S. Jerbi, K. Ennabli, and N. Romdhani
- Subjects
medicine.medical_specialty ,business.industry ,medicine.drug_class ,Antibiotics ,Hemodynamics ,Disease ,medicine.disease ,Late results ,Surgery ,Heart disorder ,Infective endocarditis ,Rheumatoid arthritis ,Active phase ,cardiovascular system ,medicine ,Cardiology and Cardiovascular Medicine ,business - Abstract
Between January 1990 and December 2006, 93 patients with infective endocarditis on native valves were operated in the active phase of the disease. The average age of our patients was 32 years with a male ascendancy. The causal heart disorder was found in 89 % of the cases, dominated by rheumatoid arthritis. The germ in cause was isolated in 52.6 % of the cases. The operative indication was hemodynamic in 29 cases, infectious in nine cases, mixed in 29 cases and embolic in 26 cases. The average operating delay was of 13 days with regard to the beginning of the antibiotic treatment. We realized a valvular aortic replacement at 32 patients with reconstruction of the ring in six cases, a valvular mitral replacement at 29 patients, a mitroaortic replacement at 21 patients, a reconstructive mitral surgery in nine cases, a valvular tricuspid replacement in one case and a reconstructive tricuspid surgery in one case. The early mortality was 13 %. The follow-up was 89 % with an average recession of 3.1 years and a late mortality of 5 %. The aim of this study is to analyze the immediate and late results of the surgery of infective endocarditis in the active phase and to bring to light the prognostic factors of mortality.
- Published
- 2010
3. Fistule coronaire : rapport d’un cas opéré et revue de la littérature
- Author
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M. Beltaïfa, S. Mlika, S. Fradi, K. Ennabli, A. Tarmiz, N. Romdhani, S. Jerbi, F. Limayem, and A. Brahem
- Subjects
medicine.medical_specialty ,business.industry ,Fistula ,Anterior Descending Coronary Artery ,medicine.disease ,Surgery ,Cardiac surgery ,Aneurysm ,medicine.anatomical_structure ,Great vessels ,Right coronary artery ,medicine.artery ,cardiovascular system ,medicine ,Circumflex ,Cardiology and Cardiovascular Medicine ,business ,Artery - Abstract
The coronary fistula is a rare abnormality making communicate a coronary artery with a cardiac cavity or a great vessel, so bypassing the myocardial capillary network. The majority of these fistulas are congenital but can nevertheless arise after a cardiac surgery. The right coronary artery and the left anterior descending coronary artery are mostly concerned. The circumflex coronary artery is rarely involved. The most frequent site of drainage is the right ventricle. We report the case of a 2-year-old child, brought by his parents for dyspnoea of effort. The diagnosis of coronary fistula was confirmed by the coronary angiography which showed an aneurysmal circumflex artery, draining into the right ventricle. The intervention was led under cardiopulmonary bypass. We proceeded to the longitudinal opening of the aneurysm then to the blindness of the fistula. The postoperative course was simple.
- Published
- 2009
4. Chirurgie du canal atrioventriculaire partiel : résultats à court et à moyen terme à propos de 56 patients opérés
- Author
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F. Alimi, C. Kortas, N. Chaouch, S. Jerbi, N. Romdhani, K. Ennabli, F. Limayem, S. Mlika, N. Khelil, and A. Tarmiz
- Subjects
medicine.medical_specialty ,Mitral regurgitation ,business.industry ,Perioperative ,Primary interatrial foramen ,medicine.disease ,Surgery ,law.invention ,medicine.anatomical_structure ,law ,Heart failure ,medicine ,Cardiopulmonary bypass ,Pericardium ,Sinus rhythm ,Cardiology and Cardiovascular Medicine ,business ,Atrioventricular block - Abstract
Between January 1991 and December 2006, 56 patients having a partial atrioventricular septal defect (AVSD) were operated. The purpose of this retrospective study is to analyze the immediate and long-term results of the surgery by granting of the importance to two main problems which are the disturbances of the rhythm and the conduction and the residual mitral regurgitation (MR). The mean age of our patients is of 10 and a half years with a net feminine ascendancy. Ninety-three percent of the patients were in regular sinus rhythm. No case of complete atrioventricular block (AVB) was noted. The MR was of grade I in 28.5% of the cases, grade II in 60% of the cases and grade III and IV in 7.5% of the cases. The MR was mild in 4% of the cases. The correction was made under cardiopulmonary bypass (CPB) and consisted of a suture of the mitral cleft in most of the cases with lock of the ostium primum by a patch of pericardium. The perioperative mortality was 1,8% of the cases. The disturbances of the rhythm and the conduction were noted in 34% of the cases. All the patients were controlled with a mean follow-up of six years and seven months. The secondary mortality was nil. The MR, at mid-term follow-up, was mild in 78% of the cases. The partial AVSD is a congenital heart disease, the spontaneous evolution of which can be burdened by complications, notably the disturbances of the rhythm and the conduction, as well as the heart failure. This justifies a premature surgical repair.
- Published
- 2009
5. Kyste hydatique emboligène du cœur droit
- Author
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C. Kortas, S. Jerbi, M. Belghith, A. Tarmiz, K. Ennabli, S. Mlika, F. Limayem, N. Khelil, and N. Romdhani
- Subjects
medicine.medical_specialty ,business.industry ,Hydatid cyst ,medicine.disease ,Echinococcosis ,Cardiac surgery ,Surgery ,Pulmonary embolism ,Cardiac chamber ,Right heart ,medicine ,Cardiology and Cardiovascular Medicine ,business ,Complication - Abstract
The cardiac location of the echinococcosis is rare. It is associated with complications potentially severe. Indeed, the break inside the cardiac chambers with pulmonary embolism is the inevitable complication of the echinococcosis of the right heart. Between January 1992 and January 2006, five patients were operated in the department of cardiac surgery of Sousse (Tunisia) for an emboligenous hydatid cyst of the right heart. The average age is of 30 years with extremes from 18 to 65 years. The cardio-pulmonary bypass is the technique of choice. We regretted a single death in immediate postoperative period. All the patients were controlled with an average recession of 36 months. A single late death was noticed. No recurrence was observed.
- Published
- 2008
6. Penetration of ceftriaxone (1 or 2 grams intravenously) into mediastinal and cardiac tissues in humans
- Author
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F. Lokiec, Majed Alaya, K. Ennabli, C. Martin, R. Said, M. Pecking, and Xavier Viviand
- Subjects
Staphylococcus aureus ,medicine.medical_specialty ,medicine.drug_class ,Antibiotics ,Bone and Bones ,law.invention ,Pharmacokinetics ,law ,Staphylococcus epidermidis ,medicine ,Cardiopulmonary bypass ,Humans ,Pericardium ,Serum Bactericidal Test ,Pharmacology (medical) ,Prospective Studies ,Endocardium ,Antibacterial agent ,Pharmacology ,Cardiopulmonary Bypass ,business.industry ,Myocardium ,Ceftriaxone ,Mediastinum ,Cephalosporins ,Surgery ,Infectious Diseases ,medicine.anatomical_structure ,Heart Valve Prosthesis ,Anesthesia ,Methicillin Resistance ,business ,Research Article ,Half-Life ,medicine.drug - Abstract
Penetration of ceftriaxone into heart tissues (valves, myocardium, auricles, and pericardium) and mediastinal tissues (fat and sternal bone) was evaluated after two regimens of ceftriaxone administration. Ten patients (group 1) were given 1,000 mg of ceftriaxone intravenously 30 min before anesthesia. Ten other patients (group 2) received the same dose and then a second 1,000-mg dose at the time of initiation of cardiopulmonary bypass. Similar and very satisfactory penetrations of ceftriaxone into tissue were observed for both groups. During opening and closure of the thorax, mean ceftriaxone concentration was in excess of the MIC at which 90% of the potential pathogens were inhibited (> or = 4 micrograms/g) in the thoracic fat, the sternal bone, and the pericardium. No significant differences between the two administration regimens in penetration of ceftriaxone into tissue were observed. During cardiopulmonary bypass, the ceftriaxone concentration was > or = 4 micrograms/g in the myocardium, the endocardium, and the auricle. The regimen of ceftriaxone administration did not significantly influence penetration of the drug into heart tissues. However, for some patients in the two groups and mainly in the sternal bone at the time of thorax closure (6 patients in group 1 and 5 patients in group 2), ceftriaxone levels in tissues were less than the MICs (4 micrograms/g) for some potential pathogens (methicillin-susceptible Staphylococcus aureus and methicillin-susceptible Staphylococcus epidermidis). During the different steps of the surgical procedures, all (10 of 10) patients in each group had tissue ceftriaxone levels greater than the MICs for gram-negative aerobic bacilli (0.1 microgram/g), except for Pseudomonas spp.
- Published
- 1996
7. Comparaison de l'analgésie extrapleurale et interpleurale par bupivacaïne après thoracotomie
- Author
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J P Auffray, N Romdhani, K. Ennabli, R. Said, T. Alouini, B Bruguerolles, and M. Alaya
- Subjects
Gynecology ,Bupivacaine ,medicine.medical_specialty ,Anesthesiology and Pain Medicine ,Regional anesthesia ,business.industry ,medicine ,General Medicine ,business ,medicine.drug - Abstract
Resume • Objectifs : Comparer l'analgesie, les effets ventilatoires et les concentrations sanguines de la bupivacaine, selon son administration par voie extrapleurale ou interpleurale apres une thoracotomie postero-laterale. • Type d'etude : Essai clinique randomise. • Patients : Vingt patients de classe ASA I et II, devant subir une thoracotomie postero-laterale reglee, ont ete randomises soit dans le groupe IP (catheter introduit dans l'espace interpleural) ou le groupe EP (catheter insere en position extrapleurale, paravertebrale, au-dessus et en arriere de la plevre parietale posterieure). • Methodes : Dans le catheter mis en place a la hauteur de T4 en fin d'intervention, 20 mL de bupivacaine a 0,5 % ont ete injectes apres le reveil complet du patient, les drains thoraciques etant clampes pendant 30 min. L'injection etait repetee toutes les 6 heures. La douleur etait evaluee apres une inspiration profonde avec une echelle visuelle analogique (EVA), avant et 1,3 et 6 heures apres l'injection. L'analgesie etait jugee efficace si le score EVA a la fin de la premiere heure etait inferieur a 30 mm. Sinon 0,1 mg · kg−1 de morphine etait injecte par voie sous-cutanee. La capacite vitale forcee (CVF) et le volume expiratoire maximal seconde (VEMS) etaient mesures avant l'intervention, ainsi qu'au 1er (J1) et 2e jour postoperatoire (J2). Des echantillons sanguins pour la mesure de la concentration plasmatique de bupivacaine etaient preleves a la 5e, 10e, 20e, 30e, 60e, 90e, 120e, 150e, 180e et 250e minute apres la premiere injection. • Resultats : La bupivacaine a produit une analgesie plus rapide, plus profonde et plus prolongee par voie extrapleurale que par voie interpleurale. L'analgesie etait efficace chez 9 patients du groupe EP vs 4 dans le groupe IP (P • Conclusions : La bupivacaine par voie extrapleurale produit une meilleure analgesie car l'anesthesique local entre mieux en contact avec les nerfs intercostaux et le risque de perte d'anesthesique par le drainage pleural est faible. C'est pourquoi cette voie est recommandee preferentiellement a la voie interpleurale pour l'analgesie apres thoracotomie postero-laterale.
- Published
- 1995
8. [Vertebral primary hydatid cyst with mediastinal involvement and paraplegia]
- Author
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F, Alimi, F, Limayem, I, Mgarrech, M, Marzouk, S, Jerbi, S, Mlika, and K, Ennabli
- Subjects
Adult ,Male ,Paraplegia ,Echinococcosis ,Mediastinum ,Animals ,Drainage ,Humans ,Spinal Diseases ,Echinococcus - Abstract
The vertebrae are the most common localization of hydatid disease of bone. This can lead to fatal consequences.We report the case of a 40-year-old-man, from a rural area, who had symptoms of medullary compression. The diagnosis of primary vertebral hydatid cyst, already suspected on the imaging data, was confirmed. A right posterolateral thoracotomy allowed drainage of the cyst and relief of the medullary compression. Medical treatment with albendazole was continued for 4 months. The postoperative course was uneventful and the symptoms of medullary compression resolved progressively. No recurrence was observed during a follow-up of 24 months.Vertebral localization of hydatid disease is the most common and serious skeletal complication. Thoracotomy allows drainage of the cyst and the pleural cavity, and relieves the medullary compression.
- Published
- 2011
9. [Bilateral popliteal artery complications of multiple hereditary exostosis]
- Author
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N, Chaouch, F, Alimi, C, Kortas, F, Limayem, A, Braham, Sinan, Mlika, S, Jerbi, and K, Ennabli
- Subjects
Adult ,Diagnosis, Differential ,Male ,Treatment Outcome ,Humans ,Popliteal Artery ,Constriction, Pathologic ,Vascular Surgical Procedures ,Aneurysm, False ,Exostoses, Multiple Hereditary - Abstract
The osseous exostose is a rare benign tumor of the bone from which the vascular complications can be of venous or arterial order, are translated in various boards. We report the case of a young adult who presents a forgery aneurysm of the right popliteal artery with the popliteal artery booby-trapped to the left. The patient benefited from surgical treatment with good clinical and radiological evolution.
- Published
- 2010
10. An 18-cm-large renal arteriovenous fistula treated by nephrectomy
- Author
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S. Jerbi, A. Tarmiz, F. Limayem, S. Mlika, M. Jaidane, N. Romdhani, K. Ennabli, and N. Ben Sorba
- Subjects
Male ,medicine.medical_specialty ,medicine.medical_treatment ,Fistula ,Renal parenchyma ,Arteriovenous fistula ,Computed tomography ,urologic and male genital diseases ,Nephrectomy ,Congenital renal artery aneurysm ,Renal Veins ,Painless Mass ,Renal Artery ,medicine ,Humans ,Vein ,Incidental Findings ,medicine.diagnostic_test ,business.industry ,General Medicine ,Middle Aged ,medicine.disease ,Aneurysm ,Surgery ,medicine.anatomical_structure ,Treatment Outcome ,Arteriovenous Fistula ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,Tomography, X-Ray Computed - Abstract
Idiopathic renal arteriovenous fistulas are extremely rare. They are believed to occur as the result of congenital renal artery aneurysm that erodes into an adjacent vein. We report a case of a 48-year-old man in whom we discovered fortuitously a painless mass of the right flank. Computed tomography revealed a huge renal artery aneurysm with giant arteriovenous fistula in the absence of any clinical stigmata. Given the size of the fistula and the partial destruction of the renal parenchyma, nephrectomy was successfully performed.
- Published
- 2009
11. [Early surgery in patients with native valve endocarditis]
- Author
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A, Tarmiz, S, Jerbi, M S, Fradi, M, Beltaïfa, S, Mlika, N, Romdhani, F, Limayem, and K, Ennabli
- Subjects
Adult ,Heart Valve Prosthesis Implantation ,Male ,Adolescent ,Rheumatic Heart Disease ,Endocarditis, Bacterial ,Middle Aged ,Combined Modality Therapy ,Anti-Bacterial Agents ,Survival Rate ,Young Adult ,Postoperative Complications ,Aortic Valve ,Child, Preschool ,Humans ,Mitral Valve ,Female ,Hospital Mortality ,Tricuspid Valve ,Child ,Aged ,Follow-Up Studies - Abstract
Between January 1990 and December 2006, 93 patients with infective endocarditis on native valves were operated in the active phase of the disease. The average age of our patients was 32 years with a male ascendancy. The causal heart disorder was found in 89 % of the cases, dominated by rheumatoid arthritis. The germ in cause was isolated in 52.6 % of the cases. The operative indication was hemodynamic in 29 cases, infectious in nine cases, mixed in 29 cases and embolic in 26 cases. The average operating delay was of 13 days with regard to the beginning of the antibiotic treatment. We realized a valvular aortic replacement at 32 patients with reconstruction of the ring in six cases, a valvular mitral replacement at 29 patients, a mitroaortic replacement at 21 patients, a reconstructive mitral surgery in nine cases, a valvular tricuspid replacement in one case and a reconstructive tricuspid surgery in one case. The early mortality was 13 %. The follow-up was 89 % with an average recession of 3.1 years and a late mortality of 5 %. The aim of this study is to analyze the immediate and late results of the surgery of infective endocarditis in the active phase and to bring to light the prognostic factors of mortality.
- Published
- 2008
12. [Coronary artery fistula: case report and review of the literature]
- Author
-
S, Jerbi, A, Tarmiz, S, Fradi, A, Brahem, M, Beltaïfa, S, Mlika, N, Romdhani, F, Limayem, and K, Ennabli
- Subjects
Male ,Child, Preschool ,Humans ,Coronary Artery Disease ,Vascular Diseases - Abstract
The coronary fistula is a rare abnormality making communicate a coronary artery with a cardiac cavity or a great vessel, so bypassing the myocardial capillary network. The majority of these fistulas are congenital but can nevertheless arise after a cardiac surgery. The right coronary artery and the left anterior descending coronary artery are mostly concerned. The circumflex coronary artery is rarely involved. The most frequent site of drainage is the right ventricle. We report the case of a 2-year-old child, brought by his parents for dyspnoea of effort. The diagnosis of coronary fistula was confirmed by the coronary angiography which showed an aneurysmal circumflex artery, draining into the right ventricle. The intervention was led under cardiopulmonary bypass. We proceeded to the longitudinal opening of the aneurysm then to the blindness of the fistula. The postoperative course was simple.
- Published
- 2008
13. [Surgery of 56 patients having a partial atrioventricular septal defect]
- Author
-
S, Jerbi, A, Tarmiz, N, Romdhani, C, Kortas, N, Chaouch, F, Alimi, N, Khelil, S, Mlika, F, Limayem, and K, Ennabli
- Subjects
Adult ,Heart Septal Defects, Ventricular ,Male ,Young Adult ,Child, Preschool ,Infant, Newborn ,Humans ,Infant ,Female ,Child ,Heart Septal Defects, Atrial ,Retrospective Studies - Abstract
Between January 1991 and December 2006, 56 patients having a partial atrioventricular septal defect (AVSD) were operated. The purpose of this retrospective study is to analyze the immediate and long-term results of the surgery by granting of the importance to two main problems which are the disturbances of the rhythm and the conduction and the residual mitral regurgitation (MR). The mean age of our patients is of 10 and a half years with a net feminine ascendancy. Ninety-three percent of the patients were in regular sinus rhythm. No case of complete atrioventricular block (AVB) was noted. The MR was of grade I in 28.5% of the cases, grade II in 60% of the cases and grade III and IV in 7.5% of the cases. The MR was mild in 4% of the cases. The correction was made under cardiopulmonary bypass (CPB) and consisted of a suture of the mitral cleft in most of the cases with lock of the ostium primum by a patch of pericardium. The perioperative mortality was 1,8% of the cases. The disturbances of the rhythm and the conduction were noted in 34% of the cases. All the patients were controlled with a mean follow-up of six years and seven months. The secondary mortality was nil. The MR, at mid-term follow-up, was mild in 78% of the cases. The partial AVSD is a congenital heart disease, the spontaneous evolution of which can be burdened by complications, notably the disturbances of the rhythm and the conduction, as well as the heart failure. This justifies a premature surgical repair.
- Published
- 2007
14. [Emboligenous hydatid cyst of the right heart]
- Author
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S, Jerbi, N, Romdhani, A, Tarmiz, C, Kortas, S, Mlika, N, Khelil, M, Belghith, F, Limayem, and K, Ennabli
- Subjects
Adult ,Cardiopulmonary Bypass ,Adolescent ,Heart Diseases ,Echinococcosis ,Animals ,Humans ,Middle Aged ,Pulmonary Embolism ,Aged ,Retrospective Studies - Abstract
The cardiac location of the echinococcosis is rare. It is associated with complications potentially severe. Indeed, the break inside the cardiac chambers with pulmonary embolism is the inevitable complication of the echinococcosis of the right heart. Between January 1992 and January 2006, five patients were operated in the department of cardiac surgery of Sousse (Tunisia) for an emboligenous hydatid cyst of the right heart. The average age is of 30 years with extremes from 18 to 65 years. The cardio-pulmonary bypass is the technique of choice. We regretted a single death in immediate postoperative period. All the patients were controlled with an average recession of 36 months. A single late death was noticed. No recurrence was observed.
- Published
- 2006
15. [Radioclinical profile of cardiopericardial hydatid: report of 17 cases]
- Author
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K, Mrad Dali, K, Tlili, M, Ly, N, Romdhani, D, Bakir, H, Gharbi, K, Ennabli, and M, Jeddi
- Subjects
Adult ,Male ,Radiography ,Adolescent ,Heart Diseases ,Echinococcosis ,Child, Preschool ,Humans ,Female ,Middle Aged ,Child ,Pericardium ,Aged - Abstract
Hydatid cysts concerning the heart are rare, accounting for 0.5 to 2% of all hydatic sites. The risk of serious complications in this location makes rapid diagnosis and surgical treatment essential. The aim of our study is to clarify the role of imaging in the diagnosis of the disease and to propose an adequate strategy. We report on 17 patients who underwent surgery for cardiopericardial hydatid cyst in the cardiovascular and thoracic unit of Sahloul hospital in Sousse from January 1988 to December 1998. Clinical investigation included in all cases chest X ray, ECG and ultrasonography (US). A computed tomography (CT) scan was performed in 14 cases, magnetic resonance imaging in three cases, transesophageal US in five cases, and coronary angiography in fsix cases. Examination for other hydatic sites was realized in all cases, and brain CT was performed in four cases. The hydatid cyst was variably localized in the left ventricle wall (five cases), the right ventricle (five cases), the pericardium (five cases), the interventricular septum (four cases), the right auricle (one case) and the left auricle (one case). The existence of other cardiac hydatid sites was found in 12 cases. All patients underwent surgery. Outcome was favorable in 14 cases, with a mean of 3 years and 5 months survey. Three patients died. The combination US-CT scan allowed a precise topographical inventory, reducing the need for MRI to the complicated cases and to the rare cases of inconclusive results by US-CT scan.
- Published
- 2003
16. Teicoplanin in cardiac surgery: intraoperative pharmacokinetics and concentrations in cardiac and mediastinal tissues
- Author
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K. Ennabli, Claude Martin, Caroline Atlani, Majed Alaya, Anthony Sertin, R. Said, and Philippe Bourget
- Subjects
Adult ,medicine.medical_specialty ,medicine.drug_class ,Antibiotics ,Gastroenterology ,Intraoperative Period ,Pharmacokinetics ,Internal medicine ,Medicine ,Humans ,Pharmacology (medical) ,Tissue Distribution ,Prospective Studies ,Cardiac Surgical Procedures ,Pharmacology ,Dose-Response Relationship, Drug ,business.industry ,Teicoplanin ,Myocardium ,Mediastinum ,Half-life ,Glycopeptide ,Cardiac surgery ,Anti-Bacterial Agents ,Regimen ,Dose–response relationship ,Infectious Diseases ,Anesthesia ,Area Under Curve ,Heart Valve Prosthesis ,Injections, Intravenous ,business ,medicine.drug ,Half-Life ,Research Article - Abstract
The concentrations of teicoplanin in the sera and mediastinal and heart tissues of 23 patients undergoing cardiac surgery were measured after two regimens of teicoplanin administration. Intraoperative pharmacokinetic parameters were also obtained. Patients were randomized into two groups. Those in group 1 were given teicoplanin at 6 mg x kg(-1) intravenously at the time of induction of anesthesia. Patients in group 2 were given teicoplanin at 12 mg x kg(-1) during the same period. The maximum concentration in serum (71 +/- 20 and 131 +/- 44 mg x l(-1)), the minimum concentration in serum (3.6 +/- 1.3 and 6.8 +/- 2.1 mg x l(-1)), the area under the concentration-time curve (AUC) from 0 to 12 h (108 +/- 20 and 217 +/- 38 microg x h x ml(-1)), and the AUC from 0 h to infinity (154 +/- 36 and 292 +/- 77 microg x h x ml(-1)) were twice as high after 12-mg x kg(-1) injections as after 6-mg x kg(-1) injections. No differences in mean residence time (9.7 +/- 4.9 and 8.4 +/- 2.7 h) or terminal half-life (8.5 +/- 3.8 and 7.5 +/- 2.3 h) were observed. Teicoplanin penetrated mediastinal and heart tissues but not sternal bone, where the antibiotic was detectable in only 1 of 13 patients in group 1 and 2 of 10 patients in group 2. In group 1, 7 of 13 patients had teicoplanin concentrations in tissue that were lower than the MIC for 90% of the strains of potential pathogens tested (MIC90) that cause infection after cardiac surgery. All of the patients in group 2 but one had teicoplanin concentrations in tissue (other than in sternal bone) far in excess of the MIC90 for the potential pathogens. In conclusion, the 12-mg x kg(-1) regimen of teicoplanin is followed by a significant increase in teicoplanin concentrations in heart and mediastinal tissues and should be preferred to the 6-mg x kg(-1) regimen if teicoplanin is selected for antimicrobial prophylaxis in open heart surgery.
- Published
- 1997
17. [Penetration of ceftriaxone (1 or 2 gr intravenous) into mediastinal and cardiac tissues in man]
- Author
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X, Viviand, M, Alaya, F, Lokiec, K, Ennabli, R, Said, M, Pecking, and C, Martin
- Subjects
Adult ,Male ,Extracorporeal Circulation ,Intraoperative Care ,Ceftriaxone ,Mediastinum ,Heart ,Bacterial Infections ,Middle Aged ,Cephalosporins ,Aortic Valve ,Heart Valve Prosthesis ,Injections, Intravenous ,Preoperative Care ,Humans ,Mitral Valve ,Female ,Prospective Studies ,Aged - Abstract
Ceftriaxone penetration into heart tissues (valves, myocardium, auricles and pericardium) and mediastinal tissues (fat and sternal bone) was evaluated after two regimens of ceftriaxone administration. Ten patients were given 1,000 g intravenously of ceftriaxone 30 min. before anesthesia. Ten other patients received the same dose and then a second 1,000 mg dose at the time of initiation of cardiopulmonary bypass. Similar and very satisfactory ceftriaxone tissue penetrations were observed in both groups. However, for some patients in the two groups and mainly in the sternal bone at the time of thorax closure, ceftriaxone levels in tissues were less than the MICs for some potential pathogens (Methicillin susceptible Staphylococcus aureus and Staphylococcus epidermidis). During the different steps of the surgical procedures all patients in both groups had tissue levels greater than the MICs for Gram negative aerobic bacilli, except for Pseudomonas spp.
- Published
- 1995
18. [Comparison of extrapleural and intrapleural analgesia with bupivacaine after thoracotomy]
- Author
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M, Alaya, J P, Auffray, T, Alouini, B, Bruguerolles, N, Romdhani, R, Said, and K, Ennabli
- Subjects
Adult ,Male ,Pain, Postoperative ,Thoracotomy ,Humans ,Pleura ,Female ,Analgesia ,Anesthetics, Local ,Middle Aged ,Bupivacaine ,Pain Measurement - Abstract
To compare the analgesic and the ventilatory effects as well as blood concentrations of bupivacaine, administered either in the extrapleural or interpleural space after posterolateral thoracotomy.Randomized clinical trial.Twenty ASA class I and II patients, scheduled for elective thoracic surgery were randomly allocated either in the IP group (catheter inserted into the interpleural space) or the EP group (catheter inserted in extrapleural position, paravertebrally above the posterior parietal pleura).In the catheter, inserted at the Th4 level at the end of the surgical procedure, 20 mL of 0.5% bupivacaine were injected after full recovery from anaesthesia, with the thoracic drains clamped for 30 min. The injection was repeated every six hours. Pain was evaluated after a deep inspiration with a visual analog scale (VAS), before and 1.3 and 6 hours after the injection. Analgesia was considered as effective if the VAS score at the end of the first hour was less than 30 mm. Otherwise 0.1 mg.kg-1 of morphine was administered subcutaneously. The forced vital capacity (FVC) and the forced expiratory volume one second (FEV1) were measured preoperatively and on 1st (D1) and 2nd postoperative Day (D2). Blood samples for measurements of plasma bupivacaine concentrations were obtained at 5, 10, 20, 30, 60, 90, 120, 150, 180 and 250 min respectively after the first injection.Bupivacaine provided a more rapid, deep and prolonged analgesia by extrapleural than by interpleural route. Analgesia was effective in 9 patients in EP group vs 4 patients in IP group (P0.05). Morphine requirements were 4 +/- 8 mg in EP group vs 17 +/- 10 mg in the IP group (P0.05). The FVC and FEV1 values were similarly decreased on D1, but recovery was better in EP group on D2 (P0.05). Bupivacaine peak concentrations in plasma were lower in EP group (0.86 +/- 0.42 microgram.mL-1) than in IP group (1.63 +/- 1.44 micrograms.mL-1), however the difference was not significant.Extrapleural administration of bupivacaine provides better analgesia as the anaesthetic agent comes in closer contact with intercostal nerves and with lower risk of loss of agent through the pleural drainage. Therefore its use is recommended preferentially over the interpleural route for analgesia after posterolateral thoracotomy.
- Published
- 1995
19. [Severe aneurysmal dilatation of the left atrium. Apropos of a case]
- Author
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M, Brigui, K, Ennabli, F, Rémadi, N, Belkhiria, S, Chabrak, and A, Bouagina
- Subjects
Diagnosis, Differential ,Male ,Humans ,Heart Aneurysm ,Child ,Pericardium ,Dilatation, Pathologic - Abstract
The authors report the case of an eleven year old child with aneurysmal dilatation of the left atrial appendage and underline the diagnostic value of Doppler echocardiography in this affectation. The two signs which led to investigation of the patient and the diagnosis of this rare congenital abnormality were bulging of the left heart border on chest X-ray and atrial fibrillation. In addition to visualising a left para-cardiac chamber communicating with the left atrium on transthoracic and transoesophageal echocardiography, colour Doppler confirmed an exchange of blood between the two chambers. This aneurysm was particularly voluminous and contained echos of spontaneous contrast, a possible source of thrombosis. Thoracic CT scan and angiocardiography did not provide any further useful information. The surgical findings confirmed the presence of a large aneurysm of the left atrial appendage and excluded partial agenesis of the pericardium, the main differential diagnosis. The aneurysm was excised under cardiopulmonary bypass, and, in particular, atrial fibrillation did not recur after surgery.
- Published
- 1994
20. [Penetration of vancomycin in cardiac and mediastinal tissues in humans]
- Author
-
C, Martin, M, Alaya, M N, Mallet, X, Viviand, K, Ennabli, R, Said, and P, de Micco
- Subjects
Adult ,Male ,Staphylococcus aureus ,Intraoperative Care ,Heart Diseases ,Myocardium ,Mediastinum ,Middle Aged ,Staphylococcal Infections ,Vancomycin ,Staphylococcus epidermidis ,Humans ,Female ,Prospective Studies ,Infusions, Intravenous - Abstract
Vancomycin penetration into heart tissues (valves, myocardium, auricles and pericardium) and mediastinal tissues (fat and sternal bone) after two regimens of administration was evaluated in a prospective, randomized study. Twenty adult patients undergoing mitral or aortic valve replacement were included in the study and divided into two groups of ten patients each: Group 1 patients were administered a 15 mg/kg intravenous dose of vancomycin over 90 min upon anesthesia. Group 2 patients received the same dose followed by a second 7.5 mg/kg intravenous dose of vancomycin over 30 min at time of initiation of the cardiopulmonary bypass. In both groups further vancomycin administrations (10 mg/kg) were performed on hour 8, 16 and 24. Plasma and tissue vancomycin concentrations were assayed by fluorescence polarization immunoassay. At different times of the surgical procedures (thorax opening and closure, period of cardiopulmonary bypass) 67 to 100% of the patients in group 1 had vancomycin concentrations in the studied tissues above the MIC 90 for Staphylococcus aureus (1 microgram/g) and Staphylococcus epidermidis (2 micrograms/g). In group 2, for the same periods and the same tissues, 72 to 100% of patients had adequate vancomycin concentrations. In group 1 patients, mean ratios of vancomycin tissue concentrations/MIC 90 were 6 +/- 2 to 20 +/- 4 for Staphylococcus aureus (MIC 90: 1 microgram/g) and 3 +/- 1 to 10 +/- 4 for Staphylococcus epidermidis (MIC 90: 2 micrograms/g). In group 2 patients, mean ratios were 8 +/- 3 to 20 +/- 4 for Staphylococcus aureus and 4 +/- 1 to 10 +/- 3 for Staphylococcus epidermidis. The use of a second dose of vancomycin in group 2 significantly increased plasma concentrations (P0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
- Published
- 1994
21. Penetration of vancomycin into mediastinal and cardiac tissues in humans
- Author
-
R. Said, K. Ennabli, Xavier Viviand, C. Martin, Majed Alaya, P. De Micco, and M.-N. Mallet
- Subjects
Adult ,medicine.medical_specialty ,Sternum ,medicine.drug_class ,Antibiotics ,medicine.disease_cause ,Bone and Bones ,Drug Administration Schedule ,law.invention ,Pharmacokinetics ,Staphylococcus epidermidis ,law ,Vancomycin ,medicine ,Cardiopulmonary bypass ,Pericardium ,Humans ,Pharmacology (medical) ,Prospective Studies ,Antibacterial agent ,Pharmacology ,Cardiopulmonary Bypass ,Intraoperative Care ,biology ,Dose-Response Relationship, Drug ,business.industry ,Myocardium ,Mediastinum ,biochemical phenomena, metabolism, and nutrition ,biology.organism_classification ,Surgery ,Infectious Diseases ,medicine.anatomical_structure ,Adipose Tissue ,Staphylococcus aureus ,Anesthesia ,business ,medicine.drug ,Research Article - Abstract
Vancomycin penetration into heart tissues (valves, myocardium, auricles, and pericardium) and mediastinal tissues (fat and sternal bone) was evaluated after two regimens of vancomycin administration. Ten patients were given 15 mg of vancomycin per kg of body weight before anesthesia. Ten other patients received the same dose and then a second 7.5-mg/kg dose at the time of initiation of cardiopulmonary bypass. Similar and satisfactory vancomycin tissue penetrations were observed in both groups. However, for some patients in the two groups, vancomycin levels in tissue were less than the MICs for potential pathogens (Staphylococcus aureus and Staphylococcus epidermidis).
- Published
- 1994
22. Une fistule artério-veineuse rénale de 18 cm traitée par néphrectomie
- Author
-
K. Ennabli, S. Mlika, M. Jaidane, F. Limayem, S. Jerbi, N. Romdhani, A. Tarmiz, and N. Ben Sorba
- Subjects
Gynecology ,medicine.medical_specialty ,business.industry ,Medicine ,Electrical and Electronic Engineering ,urologic and male genital diseases ,business ,Atomic and Molecular Physics, and Optics - Abstract
Les fistules arterio-veineuses renales idiopathiques sont extremement rares. Elles sont supposees etre le resultat d’une erosion d’une veine renale par un anevrysme congenital de l’artere renale adjacente. Nous rapportons ici le cas d’un homme de 48 ans chez qui nous avons decouvert fortuitement une masse douloureuse du flanc droit. Un angioscanner a revele la presence d’un volumineux anevrysme de l’artere renale droite avec fistule arterio-veineuse geante, en l’absence de tout stigmate clinique. Etant donne la taille de la fistule et de la destruction partielle du parenchyme renal, une nephrectomie a ete decidee et realisee avec succes.
- Published
- 2010
23. RP28 Anevrysme de l’aorte abdominale du nouveau-ne et nourisson : presentation de 2 cas
- Author
-
K. Monastiri, F. Limayem, S. Abroug, K. Ennabli, M. Dhahbi, I. Hasni-Bouraoui, M. Souei-Mhiri, K. Tlili-Graiess, and K. Mrad Daly
- Subjects
Radiological and Ultrasound Technology ,Radiology, Nuclear Medicine and imaging - Abstract
Objectifs Rapporter deux observations tres rares d’anevrysme de l’aorte abdominale (AAA) decouverts chez un nouveau-ne et un tres jeune nourrisson. Materiels et methodes Les deux dossiers d’AAA, colliges en 2002 et en 2003, comprenaient les donnees cliniques, biologiques, de l’imagerie et les modalites therapeutiques. Les patients ont ete explores par echo-Doppler (ED), scanner et angiographie numerisee. Resultats Cas 1 : Premature de 28 SA, connu porteur en antenatal d’une double masse kystique communicante abdomino-pelvienne. L’ED post-natal decouvrait un AAA avec bilans cardiaques et hematologiques normaux. Le suivi en ED demontrait la thrombose partielle de l’AAA avec une hypertension arterielle des 7 mois normalisee sous traitement. Une angiographie etait realisee a 1 an suivi 3 mois apres, une resection de la poche anevrysmale. Cas 2 : Jumelle nee a 32 SA, ayant souffert en neonatal d’infection nosocomiale et de necrose ischemique de 2 orteils gauches. Decouverte a 4 mois d’un deficit en proteine C et en ED, d’un AAA etendu a l’iliaque primitive droite confirme par angioscanner. L’enfant a ete opere a 8 mois, avec suivi immediat et a 1 mois en ED. Conclusion Les AAA chez le nouveau-ne et le jeune enfant sont tres rares et souvent associes a des malformations cardio-vasculaires ou compliquant un catheterisme ombilical infecte. Les autres etiologies sont encore plus rares et les formes congenitales sont rarissimes. Diagnostic positif et evaluation de l’extension sont parfaitement assures par FED a cet âge ou l’angiographie est relativement difficile et agressive.
- Published
- 2004
24. Evaluation De La Gravité En Chirurgie Cardiaque: Comparaison Du Saps II Et De l'Apache II
- Author
-
H. Hmouda, M. Alaya, F. Haddad, K. Ennabli, S. Chelbi, S. Mlika, and R. Said
- Subjects
Anesthesiology and Pain Medicine ,General Medicine - Published
- 1995
25. Peut-On Prevenir La Dysfonction Renale Lors De La Chirurgie Cardiaque ?
- Author
-
M. Alaya, A. Gharsallah, K. Ennabli, F. Haddad, S. Souguir, S. Mlika, and R. Said
- Subjects
Anesthesiology and Pain Medicine ,General Medicine - Published
- 1995
26. Vancomycine en antibioprophylaxie: Pénétration dans les tissus cardiaques et médiastinaux
- Author
-
R. Said, M. Alaya, P. De Micco, C. Martin, K. Ennabli, and Xavier Viviand
- Subjects
Anesthesiology and Pain Medicine ,General Medicine - Published
- 1993
27. Effets comparatifs de deux posologies d’aprotinine sur la réduction du saignement après chirurgie valvulaire sous CEC
- Author
-
S. Chelbi, T. Alouini, K Ennabli, M. Alaya, F. Limayem, S. Souguir, and R. Said
- Subjects
Anesthesiology and Pain Medicine ,General Medicine - Published
- 1993
28. [Experience in treating hydatid cyst of the liver at the Hôpital Farhat Hached de Sousse]
- Author
-
K, Ennabli, S, Gharbi, M, Farhat, and R B, Haj Hamida
- Subjects
Adult ,Male ,Echinococcosis, Hepatic ,Postoperative Complications ,Humans ,Female ,Middle Aged ,Child ,Prognosis - Published
- 1979
29. [Vascular perforation caused by central venous catheter]
- Author
-
R, Saïd, R, Ben Hamida, K, Ennabli, A, Jerbi, and C, Saint-Maurice
- Subjects
Adult ,Male ,Pleural Effusion ,Rupture ,Catheters, Indwelling ,Humans ,Saphenous Vein ,Jugular Veins ,Phlebitis - Published
- 1984
30. [Analytical study of 80 cases of lithiasic cholangitis]
- Author
-
K, Ennabli and M, Jemni
- Subjects
Adult ,Male ,Cholangitis ,Cholelithiasis ,Humans ,Female ,Bile Duct Diseases ,Middle Aged ,Aged ,Retrospective Studies - Abstract
A retrospective study of 80 cases of lithiasic cholangitis treated between 1970 and 1982 demonstrated that cholangitis represents 45 p. 100 of the clinical manifestations of stones in the main biliary tract and 6.5 p. 100 of biliary surgery. This complication mainly affects female patients (3 out of 4 cases) and charcot's triad is the form that is most frequently encountered (81.25 p. 100 of cases). External drainage of the main biliary tract by Kerr's drain was performed in 32,5 p. 100 of cases and internal bypass operations in the remainder (A.B.D. : 36,15 p. 100, sphincterotomy : 32,25 p. 100). Mortality has reached 11,25 p. 100, including over half of the cases by cholangitis of uremic origin.
- Published
- 1984
31. [Hydatid cysts of the liver open into the bronchi and pleura. Apropos of 18 cases]
- Author
-
K, Ennabli
- Subjects
Adult ,Male ,Echinococcosis, Hepatic ,Biliary Fistula ,Fistula ,Middle Aged ,Pleural Diseases ,Postoperative Complications ,Humans ,Female ,Bronchial Fistula ,Child ,Aged ,Follow-Up Studies - Published
- 1984
32. [Abdominothoracic hydatidosis. Evaluation of 5 years' activity of the surgical service of the Farhat Hached de Sousse University Hospital]
- Author
-
R, Letaief, A, Khalfallah, R B, Hamida, A, Jerbi, R, Said, K, Ennabli, M, Kehila, H, Khabthani, and S, Gharbi
- Subjects
Adult ,Male ,Echinococcosis, Hepatic ,Echinococcosis, Pulmonary ,Tunisia ,Adolescent ,Hospital Departments ,Middle Aged ,Hospitals, University ,Echinococcosis ,Child, Preschool ,Humans ,Female ,Child ,Hospitals, Teaching ,Surgery Department, Hospital ,Aged - Abstract
The authors report a statistical study of abdominal and/or pulmonary locations of hydatid cyst disease operated on at Farhat Hached hospital (Sousse, Tunisia) during a five years period. Between January 1980 and December 1984, 465 patients were operated on by Pr Gharbi's staff. 255 patients had hydatid cyst disease of the liver. 68% of them were more than 30 years of age and 67% were females. 16% of these patients had obviously complicated lesions. This rate was as high in adults as in children less then 15 years old. The basic surgical procedure was a more or less extensive partial pericystectomy. The mean hospital stay in surgical environment was 33 days. The mortality rate in this group was 5.9% (15 deaths). 195 patients had pulmonary hydatid cyst disease. 83% of them were less then 30 years of age and 57% were males. The complication rate at presentation was 30% and was similar among adults and children less 15 years of age. Despite the fact that 15% of these patients have been treated by lobectomy, the basic surgical procedure in this group was also a more or less extensive partial pericystectomy. The mean hospital stay in surgical environment was 15 days and the mortality rate 0.5% (one death). About the other locations of the disease, 7 cases of peritoneal ecchinococcosis were recorded. The youngest patient was 15 years old. The interventions necessitated by the whole of these locations represented no less than 8.65% of the surgical procedures performed in our service.
- Published
- 1985
33. [Hydatid cysts of the liver opening into the bile ducts: apropos of 12 cases]
- Author
-
K, Ennabli and S, Gharbi
- Subjects
Echinococcosis, Hepatic ,Adolescent ,Rupture, Spontaneous ,Child, Preschool ,Humans ,Biliary Tract ,Child ,Cholangiography - Published
- 1981
34. Extra-anatomic bypass grafting in the lower extremity
- Author
-
F, Laurendeau, J, Lassonde, and K, Ennabli
- Subjects
Adult ,Femoral Artery ,Male ,Risk ,Postoperative Complications ,Axillary Artery ,Humans ,Female ,Thrombosis ,Middle Aged ,Aged ,Blood Vessel Prosthesis - Abstract
Between January 1975 and December 1980, 104 extra-anatomic bypasses were performed on 102 patients. Of these, there were 81 femorofemoral bypasses on 80 patients and 23 axillofemoral bypasses on 22 patients. Those who underwent femorofemoral grafting were divided into three groups: group 1 - 18 patients who had undergone previous aortofemoral bypass grafting with occlusion of one limb of the graft, group 2 - 17 patients who were considered to be at high risk and group 3 - 45 patients who could have tolerated a conventional reconstructive procedure. Our results indicate that the cumulative patency rate of the femorofemoral bypass at the end of 1 year and 5 years is good and that this operation is an excellent first choice procedure in cases of unilateral iliac disease, to relieve severe ischemia or disabling claudication, whether the patient is a poor or good operative risk. On the other hand, axillofemoral grafting has a lower patency rate and should be reserved for high-risk patients and for the relief of severe ischemia only.
- Published
- 1983
35. [Influence of ventricular function on the postoperative course of patients with anterior ventricular aneurysms]
- Author
-
J M, González Santos, K, Ennabli, M L, González Santos, M, Gómez Recio, X, Bosch, J, Lesperance, and L C, Pelletier
- Subjects
Adult ,Male ,Heart Ventricles ,Humans ,Female ,Heart ,Heart Aneurysm ,Middle Aged ,Aged ,Follow-Up Studies
36. [Vertebral primary hydatid cyst with mediastinal involvement and paraplegia].
- Author
-
Alimi F, Limayem F, Mgarrech I, Marzouk M, Jerbi S, Mlika S, and Ennabli K
- Subjects
- Adult, Animals, Drainage, Echinococcosis complications, Echinococcosis surgery, Humans, Male, Mediastinum surgery, Paraplegia surgery, Spinal Diseases complications, Spinal Diseases surgery, Echinococcosis diagnosis, Echinococcus, Mediastinum pathology, Paraplegia parasitology, Spinal Diseases parasitology
- Abstract
Introduction: The vertebrae are the most common localization of hydatid disease of bone. This can lead to fatal consequences., Case Report: We report the case of a 40-year-old-man, from a rural area, who had symptoms of medullary compression. The diagnosis of primary vertebral hydatid cyst, already suspected on the imaging data, was confirmed. A right posterolateral thoracotomy allowed drainage of the cyst and relief of the medullary compression. Medical treatment with albendazole was continued for 4 months. The postoperative course was uneventful and the symptoms of medullary compression resolved progressively. No recurrence was observed during a follow-up of 24 months., Conclusion: Vertebral localization of hydatid disease is the most common and serious skeletal complication. Thoracotomy allows drainage of the cyst and the pleural cavity, and relieves the medullary compression., (Copyright © 2012. Published by Elsevier Masson SAS.)
- Published
- 2012
- Full Text
- View/download PDF
37. [Bilateral popliteal artery complications of multiple hereditary exostosis].
- Author
-
Chaouch N, Alimi F, Kortas C, Limayem F, Braham A, Mlika S, Jerbi S, and Ennabli K
- Subjects
- Adult, Aneurysm, False diagnosis, Aneurysm, False surgery, Constriction, Pathologic surgery, Diagnosis, Differential, Humans, Male, Treatment Outcome, Vascular Surgical Procedures, Aneurysm, False etiology, Exostoses, Multiple Hereditary complications, Popliteal Artery pathology, Popliteal Artery surgery
- Abstract
The osseous exostose is a rare benign tumor of the bone from which the vascular complications can be of venous or arterial order, are translated in various boards. We report the case of a young adult who presents a forgery aneurysm of the right popliteal artery with the popliteal artery booby-trapped to the left. The patient benefited from surgical treatment with good clinical and radiological evolution., (Copyright © 2011. Published by Elsevier SAS.)
- Published
- 2011
- Full Text
- View/download PDF
38. An 18-cm-large renal arteriovenous fistula treated by nephrectomy.
- Author
-
Tarmiz A, Jerbi S, Jaïdane M, Ben Sorba N, Mlika S, Romdhani N, Limayem F, and Ennabli K
- Subjects
- Aneurysm complications, Aneurysm diagnostic imaging, Arteriovenous Fistula diagnostic imaging, Arteriovenous Fistula etiology, Humans, Incidental Findings, Male, Middle Aged, Renal Artery diagnostic imaging, Renal Veins diagnostic imaging, Tomography, X-Ray Computed, Treatment Outcome, Aneurysm surgery, Arteriovenous Fistula surgery, Nephrectomy, Renal Artery surgery, Renal Veins surgery
- Abstract
Idiopathic renal arteriovenous fistulas are extremely rare. They are believed to occur as the result of congenital renal artery aneurysm that erodes into an adjacent vein. We report a case of a 48-year-old man in whom we discovered fortuitously a painless mass of the right flank. Computed tomography revealed a huge renal artery aneurysm with giant arteriovenous fistula in the absence of any clinical stigmata. Given the size of the fistula and the partial destruction of the renal parenchyma, nephrectomy was successfully performed., (Copyright 2010. Published by Elsevier Inc.)
- Published
- 2010
- Full Text
- View/download PDF
39. [Early surgery in patients with native valve endocarditis].
- Author
-
Tarmiz A, Jerbi S, Fradi MS, Beltaïfa M, Mlika S, Romdhani N, Limayem F, and Ennabli K
- Subjects
- Adolescent, Adult, Aged, Anti-Bacterial Agents therapeutic use, Aortic Valve surgery, Child, Child, Preschool, Combined Modality Therapy, Endocarditis, Bacterial diagnosis, Endocarditis, Bacterial mortality, Female, Follow-Up Studies, Hospital Mortality, Humans, Male, Middle Aged, Mitral Valve surgery, Postoperative Complications diagnosis, Postoperative Complications mortality, Rheumatic Heart Disease diagnosis, Rheumatic Heart Disease mortality, Rheumatic Heart Disease surgery, Survival Rate, Tricuspid Valve surgery, Young Adult, Endocarditis, Bacterial surgery, Heart Valve Prosthesis Implantation
- Abstract
Between January 1990 and December 2006, 93 patients with infective endocarditis on native valves were operated in the active phase of the disease. The average age of our patients was 32 years with a male ascendancy. The causal heart disorder was found in 89 % of the cases, dominated by rheumatoid arthritis. The germ in cause was isolated in 52.6 % of the cases. The operative indication was hemodynamic in 29 cases, infectious in nine cases, mixed in 29 cases and embolic in 26 cases. The average operating delay was of 13 days with regard to the beginning of the antibiotic treatment. We realized a valvular aortic replacement at 32 patients with reconstruction of the ring in six cases, a valvular mitral replacement at 29 patients, a mitroaortic replacement at 21 patients, a reconstructive mitral surgery in nine cases, a valvular tricuspid replacement in one case and a reconstructive tricuspid surgery in one case. The early mortality was 13 %. The follow-up was 89 % with an average recession of 3.1 years and a late mortality of 5 %. The aim of this study is to analyze the immediate and late results of the surgery of infective endocarditis in the active phase and to bring to light the prognostic factors of mortality., (Copyright (c) 2009 Elsevier Masson SAS. All rights reserved.)
- Published
- 2010
- Full Text
- View/download PDF
40. [Coronary artery fistula: case report and review of the literature].
- Author
-
Jerbi S, Tarmiz A, Fradi S, Brahem A, Beltaïfa M, Mlika S, Romdhani N, Limayem F, and Ennabli K
- Subjects
- Child, Preschool, Humans, Male, Vascular Diseases diagnosis, Vascular Diseases surgery, Coronary Artery Disease diagnosis, Coronary Artery Disease surgery
- Abstract
The coronary fistula is a rare abnormality making communicate a coronary artery with a cardiac cavity or a great vessel, so bypassing the myocardial capillary network. The majority of these fistulas are congenital but can nevertheless arise after a cardiac surgery. The right coronary artery and the left anterior descending coronary artery are mostly concerned. The circumflex coronary artery is rarely involved. The most frequent site of drainage is the right ventricle. We report the case of a 2-year-old child, brought by his parents for dyspnoea of effort. The diagnosis of coronary fistula was confirmed by the coronary angiography which showed an aneurysmal circumflex artery, draining into the right ventricle. The intervention was led under cardiopulmonary bypass. We proceeded to the longitudinal opening of the aneurysm then to the blindness of the fistula. The postoperative course was simple.
- Published
- 2009
- Full Text
- View/download PDF
41. [Surgery of 56 patients having a partial atrioventricular septal defect].
- Author
-
Jerbi S, Tarmiz A, Romdhani N, Kortas C, Chaouch N, Alimi F, Khelil N, Mlika S, Limayem F, and Ennabli K
- Subjects
- Adult, Child, Child, Preschool, Female, Humans, Infant, Infant, Newborn, Male, Retrospective Studies, Young Adult, Heart Septal Defects, Atrial surgery, Heart Septal Defects, Ventricular surgery
- Abstract
Between January 1991 and December 2006, 56 patients having a partial atrioventricular septal defect (AVSD) were operated. The purpose of this retrospective study is to analyze the immediate and long-term results of the surgery by granting of the importance to two main problems which are the disturbances of the rhythm and the conduction and the residual mitral regurgitation (MR). The mean age of our patients is of 10 and a half years with a net feminine ascendancy. Ninety-three percent of the patients were in regular sinus rhythm. No case of complete atrioventricular block (AVB) was noted. The MR was of grade I in 28.5% of the cases, grade II in 60% of the cases and grade III and IV in 7.5% of the cases. The MR was mild in 4% of the cases. The correction was made under cardiopulmonary bypass (CPB) and consisted of a suture of the mitral cleft in most of the cases with lock of the ostium primum by a patch of pericardium. The perioperative mortality was 1,8% of the cases. The disturbances of the rhythm and the conduction were noted in 34% of the cases. All the patients were controlled with a mean follow-up of six years and seven months. The secondary mortality was nil. The MR, at mid-term follow-up, was mild in 78% of the cases. The partial AVSD is a congenital heart disease, the spontaneous evolution of which can be burdened by complications, notably the disturbances of the rhythm and the conduction, as well as the heart failure. This justifies a premature surgical repair.
- Published
- 2009
- Full Text
- View/download PDF
42. [Emboligenous hydatid cyst of the right heart].
- Author
-
Jerbi S, Romdhani N, Tarmiz A, Kortas C, Mlika S, Khelil N, Belghith M, Limayem F, and Ennabli K
- Subjects
- Adolescent, Adult, Aged, Animals, Cardiopulmonary Bypass, Humans, Middle Aged, Retrospective Studies, Echinococcosis surgery, Heart Diseases parasitology, Heart Diseases surgery, Pulmonary Embolism parasitology, Pulmonary Embolism surgery
- Abstract
The cardiac location of the echinococcosis is rare. It is associated with complications potentially severe. Indeed, the break inside the cardiac chambers with pulmonary embolism is the inevitable complication of the echinococcosis of the right heart. Between January 1992 and January 2006, five patients were operated in the department of cardiac surgery of Sousse (Tunisia) for an emboligenous hydatid cyst of the right heart. The average age is of 30 years with extremes from 18 to 65 years. The cardio-pulmonary bypass is the technique of choice. We regretted a single death in immediate postoperative period. All the patients were controlled with an average recession of 36 months. A single late death was noticed. No recurrence was observed.
- Published
- 2008
- Full Text
- View/download PDF
43. Primitive cardiac sarcomas: about 2 cases.
- Author
-
Jerbi S, Romdhani N, Tarmiz A, Mlika S, Nizar K, Beltaïfa M, Belghith M, Limayem F, and Ennabli K
- Subjects
- Adult, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Echocardiography, Fatal Outcome, Female, Heart Atria surgery, Humans, Male, Middle Aged, Prognosis, Treatment Outcome, Heart Neoplasms diagnosis, Heart Neoplasms drug therapy, Heart Neoplasms surgery, Sarcoma diagnosis, Sarcoma drug therapy, Sarcoma surgery
- Abstract
Background: the cardiac sarcomas, although very rare, represent the quasi-totality of the primitive sly tumors of the heart, Aim: it is about a retrospective study of two cases of cardiac sarcomas operated in Sahloul university hospital of Sousse., Cases: it is about a woman and a man: The respective ages were 22 and 45 years. The clinical pattern of the patients was polymorphic and the diagnosis put by cardiac echography. Both patients had a surgical resection and a chemotherapy. Both patients died in 13 and 18 months after the diagnosis., Conclusion: because of the extreme rarity of the cardiac sarcomas, there is no precise therapeutic strategy. The only consensus concerns the surgery as soon as the diagnosis of cardiac tumor is put. The prognosis of these tumors is extremely redoubtable with a survival which does not exceed 2 years after the beginning of the symptomatology.
- Published
- 2007
44. [Cor triatriatum: of six operated patients report].
- Author
-
Jerbi S, Romdhani N, Aly F, Kortas C, Mlika S, Belghith M, Limayem F, and Ennabli K
- Subjects
- Adolescent, Child, Preschool, Echocardiography, Female, Follow-Up Studies, Humans, Infant, Male, Time Factors, Treatment Outcome, Cor Triatriatum diagnostic imaging, Cor Triatriatum surgery
- Abstract
Six cases of cortriatriatum operated between January 1990 and April 2004. Their ages ranged from 3 months to 22 years. Associated lesions are present in 4 patients. They consisted mostly of interatrial defects. The echocardiography has been considered the procedure of choice for the diagnosis. Results of surgery were excellent for all patients with a mean follow up of 5 years.
- Published
- 2006
45. [Congenital abdominal infrarenal aortic aneurysm in infants: 2 case reports and literature review].
- Author
-
Mlika S, Limayem F, Monastiri K, Aly F, Jerbi S, Dammak S, Romdhani N, and Ennabli K
- Subjects
- Aortic Aneurysm, Abdominal surgery, Blood Vessel Prosthesis, Female, Humans, Infant, Male, Polytetrafluoroethylene, Aortic Aneurysm, Abdominal congenital, Aortic Aneurysm, Abdominal diagnosis
- Abstract
Abdominal aortic aneurysm is extremely rare in infant and is generally due to infection, umbilical artery catheterization, vasculitis, connective tissue diseases and tuberous sclerosis. At the absence of these evident causes, it is a congenital primary aortic aneurysm which is exceedingly rare and only a few cases have of which have been reported. Here we report two cases of aortic wall reconstruction done by a Gore tex patch. The immediate result is excellent with a reestablishment of the femoral pulse and an excellent Doppler control. The problem which we may face in the future is probably the aortic out come with this Gore tex patch a continaons follow up of these patients is necessary.
- Published
- 2006
46. [Chronic aortic regurgitation with left ventricular dysfonction].
- Author
-
Jerbi S, Limayem F, Kortas C, Hamida N, Mlika FA, Romdani N, and Ennabli K
- Subjects
- Adult, Echocardiography, Female, Humans, Male, Middle Aged, Prognosis, Retrospective Studies, Aortic Valve Insufficiency complications, Aortic Valve Insufficiency surgery, Heart Valve Prosthesis Implantation mortality, Ventricular Dysfunction, Left etiology
- Abstract
We studied fifty one patients (40 men and 11 women) under going valve replacement from 1990 to 2002 for aortic regurgitation and had left ventricular dysfunction. 45% patients were in class III or IV of New York Heart Association (NYHA). All patients were investigated by echocardiography (left ventricular ejection fraction [LVEF] < 50%) - Peroperative mortality was 5.8% due to myocardial failure. 81.4% of survivors were followed duering a mean period of 24 months (rangis from 3 to 67 months) after valve replacement.
- Published
- 2005
47. [Cardio-pericardial hydatid cyst. Report of 19 cases].
- Author
-
Jerbi S, Kortas C, Dammak S, Hamida N, Aly F, Mlika S, Romdhani N, Limayem F, and Ennabli K
- Subjects
- Adolescent, Adult, Aged, Cardiac Surgical Procedures methods, Child, Child, Preschool, Female, Humans, Male, Middle Aged, Retrospective Studies, Treatment Outcome, Echinococcosis surgery, Heart Diseases microbiology, Heart Diseases surgery, Pericardium microbiology
- Abstract
From May 1991 to July 2003, 19 patients (9 men and 10 women), of 30 years average age were operated in our department service for surgical cure of cardio-pericardial hydatid cysts. The TEE constitutes the examination of choice in the cardio-pericardial diagnosis of hydatid cyst. The surgery under CPB is the technique of choice, we practiced used 15 times. The left ventricular localization is most frequent. We deplore only death into post-operative immediate. The post-operative was course simple at the majority of our patients. 17 patients could be controlled remotely of the intervention with 35.5 months an average passing. We deplore 2 late deaths. No relapse was observed.
- Published
- 2004
48. [Radioclinical profile of cardiopericardial hydatid: report of 17 cases].
- Author
-
Mrad Dali K, Tlili K, Ly M, Romdhani N, Bakir D, Gharbi H, Ennabli K, and Jeddi M
- Subjects
- Adolescent, Adult, Aged, Child, Child, Preschool, Echinococcosis surgery, Female, Heart Diseases surgery, Humans, Male, Middle Aged, Radiography, Echinococcosis diagnostic imaging, Heart Diseases diagnostic imaging, Heart Diseases parasitology, Pericardium diagnostic imaging, Pericardium parasitology
- Abstract
Hydatid cysts concerning the heart are rare, accounting for 0.5 to 2% of all hydatic sites. The risk of serious complications in this location makes rapid diagnosis and surgical treatment essential. The aim of our study is to clarify the role of imaging in the diagnosis of the disease and to propose an adequate strategy. We report on 17 patients who underwent surgery for cardiopericardial hydatid cyst in the cardiovascular and thoracic unit of Sahloul hospital in Sousse from January 1988 to December 1998. Clinical investigation included in all cases chest X ray, ECG and ultrasonography (US). A computed tomography (CT) scan was performed in 14 cases, magnetic resonance imaging in three cases, transesophageal US in five cases, and coronary angiography in fsix cases. Examination for other hydatic sites was realized in all cases, and brain CT was performed in four cases. The hydatid cyst was variably localized in the left ventricle wall (five cases), the right ventricle (five cases), the pericardium (five cases), the interventricular septum (four cases), the right auricle (one case) and the left auricle (one case). The existence of other cardiac hydatid sites was found in 12 cases. All patients underwent surgery. Outcome was favorable in 14 cases, with a mean of 3 years and 5 months survey. Three patients died. The combination US-CT scan allowed a precise topographical inventory, reducing the need for MRI to the complicated cases and to the rare cases of inconclusive results by US-CT scan.
- Published
- 2000
49. Teicoplanin in cardiac surgery: intraoperative pharmacokinetics and concentrations in cardiac and mediastinal tissues.
- Author
-
Martin C, Bourget P, Alaya M, Sertin A, Atlani C, Ennabli K, and Said R
- Subjects
- Adult, Anti-Bacterial Agents administration & dosage, Anti-Bacterial Agents blood, Area Under Curve, Dose-Response Relationship, Drug, Half-Life, Heart Valve Prosthesis, Humans, Injections, Intravenous, Intraoperative Period, Mediastinum, Myocardium chemistry, Prospective Studies, Teicoplanin administration & dosage, Teicoplanin blood, Tissue Distribution, Anti-Bacterial Agents pharmacokinetics, Cardiac Surgical Procedures, Teicoplanin pharmacokinetics
- Abstract
The concentrations of teicoplanin in the sera and mediastinal and heart tissues of 23 patients undergoing cardiac surgery were measured after two regimens of teicoplanin administration. Intraoperative pharmacokinetic parameters were also obtained. Patients were randomized into two groups. Those in group 1 were given teicoplanin at 6 mg x kg(-1) intravenously at the time of induction of anesthesia. Patients in group 2 were given teicoplanin at 12 mg x kg(-1) during the same period. The maximum concentration in serum (71 +/- 20 and 131 +/- 44 mg x l(-1)), the minimum concentration in serum (3.6 +/- 1.3 and 6.8 +/- 2.1 mg x l(-1)), the area under the concentration-time curve (AUC) from 0 to 12 h (108 +/- 20 and 217 +/- 38 microg x h x ml(-1)), and the AUC from 0 h to infinity (154 +/- 36 and 292 +/- 77 microg x h x ml(-1)) were twice as high after 12-mg x kg(-1) injections as after 6-mg x kg(-1) injections. No differences in mean residence time (9.7 +/- 4.9 and 8.4 +/- 2.7 h) or terminal half-life (8.5 +/- 3.8 and 7.5 +/- 2.3 h) were observed. Teicoplanin penetrated mediastinal and heart tissues but not sternal bone, where the antibiotic was detectable in only 1 of 13 patients in group 1 and 2 of 10 patients in group 2. In group 1, 7 of 13 patients had teicoplanin concentrations in tissue that were lower than the MIC for 90% of the strains of potential pathogens tested (MIC90) that cause infection after cardiac surgery. All of the patients in group 2 but one had teicoplanin concentrations in tissue (other than in sternal bone) far in excess of the MIC90 for the potential pathogens. In conclusion, the 12-mg x kg(-1) regimen of teicoplanin is followed by a significant increase in teicoplanin concentrations in heart and mediastinal tissues and should be preferred to the 6-mg x kg(-1) regimen if teicoplanin is selected for antimicrobial prophylaxis in open heart surgery.
- Published
- 1997
- Full Text
- View/download PDF
50. Penetration of ceftriaxone (1 or 2 grams intravenously) into mediastinal and cardiac tissues in humans.
- Author
-
Martin C, Viviand X, Alaya M, Lokiec F, Ennabli K, Said R, and Pecking M
- Subjects
- Bone and Bones metabolism, Cardiopulmonary Bypass, Ceftriaxone administration & dosage, Cephalosporins administration & dosage, Half-Life, Heart Valve Prosthesis, Humans, Methicillin Resistance, Prospective Studies, Serum Bactericidal Test, Staphylococcus aureus drug effects, Staphylococcus epidermidis drug effects, Ceftriaxone pharmacokinetics, Cephalosporins pharmacokinetics, Mediastinum physiology, Myocardium metabolism
- Abstract
Penetration of ceftriaxone into heart tissues (valves, myocardium, auricles, and pericardium) and mediastinal tissues (fat and sternal bone) was evaluated after two regimens of ceftriaxone administration. Ten patients (group 1) were given 1,000 mg of ceftriaxone intravenously 30 min before anesthesia. Ten other patients (group 2) received the same dose and then a second 1,000-mg dose at the time of initiation of cardiopulmonary bypass. Similar and very satisfactory penetrations of ceftriaxone into tissue were observed for both groups. During opening and closure of the thorax, mean ceftriaxone concentration was in excess of the MIC at which 90% of the potential pathogens were inhibited (> or = 4 micrograms/g) in the thoracic fat, the sternal bone, and the pericardium. No significant differences between the two administration regimens in penetration of ceftriaxone into tissue were observed. During cardiopulmonary bypass, the ceftriaxone concentration was > or = 4 micrograms/g in the myocardium, the endocardium, and the auricle. The regimen of ceftriaxone administration did not significantly influence penetration of the drug into heart tissues. However, for some patients in the two groups and mainly in the sternal bone at the time of thorax closure (6 patients in group 1 and 5 patients in group 2), ceftriaxone levels in tissues were less than the MICs (4 micrograms/g) for some potential pathogens (methicillin-susceptible Staphylococcus aureus and methicillin-susceptible Staphylococcus epidermidis). During the different steps of the surgical procedures, all (10 of 10) patients in each group had tissue ceftriaxone levels greater than the MICs for gram-negative aerobic bacilli (0.1 microgram/g), except for Pseudomonas spp.
- Published
- 1996
- Full Text
- View/download PDF
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