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11 results on '"K. Consentius"'

2. [Duodenal ulcer - multicenter double-blind study with proglumide]

Author

W, Bergemann, K, Consentius, H E, Braun, H, Hirschmann, B, Marowski, A, Munck, H U, Rehs, D, Stopik, and G, Wilke

Subjects
Adult, Male, Wound Healing, Glutamine, Silicic Acid, Middle Aged, Proglumide, Double-Blind Method, Magnesium Silicates, Duodenal Ulcer, Humans, Female, Magnesium, Duodenoscopy, Aged
Abstract

In a randomised multicenter double blind study we investigated the healing-rate with proglumid and an antacid drug, studying 70 in- and outpatients with florid duodenal ulcer. We evaluated the size and depth of 59 chronic duodenal ulcers in 52 patients with endoscopic and x-ray-investigations before and after four-week-treatment. Inpatients of the proglumid-group had a significant higher healing-rate than inpatients in the antacid-group (95% against 70%, p less than 0.05). As found in endoscopy the outpatients in the proglumid-group had a higher healing-rate, but because of the smaller number of patients the difference was not significant. Summarized the in- and outpatients, the proglumid-group had a healing-rate of 83%, the antacid-group of 60% (p less than 0.05). Bigger ulcers with a size more than 120 mm2 at the beginning showed a significant better healing with proglumid than with the antacid-drug (t/2 = 14.6 resp. 24.6 days). With x-ray-examination we could not find differences of healing between the two groups, but younger patients often were not examined. The symptoms of patients did not show a significant difference during the healing-course. We could not find any side-effects. Proglumid is an effective drug for the healing of chronic duodenal ulcers.

Published
1981

8. [Duodenal ulcer - multicenter double-blind study with proglumide].

Author

Bergemann W, Consentius K, Braun HE, Hirschmann H, Marowski B, Munck A, Rehs HU, Stopik D, and Wilke G

Subjects
Adult, Aged, Double-Blind Method, Duodenoscopy, Female, Humans, Magnesium therapeutic use, Male, Middle Aged, Silicic Acid therapeutic use, Wound Healing drug effects, Duodenal Ulcer drug therapy, Glutamine analogs & derivatives, Magnesium Silicates, Proglumide therapeutic use
Abstract

In a randomised multicenter double blind study we investigated the healing-rate with proglumid and an antacid drug, studying 70 in- and outpatients with florid duodenal ulcer. We evaluated the size and depth of 59 chronic duodenal ulcers in 52 patients with endoscopic and x-ray-investigations before and after four-week-treatment. Inpatients of the proglumid-group had a significant higher healing-rate than inpatients in the antacid-group (95% against 70%, p less than 0.05). As found in endoscopy the outpatients in the proglumid-group had a higher healing-rate, but because of the smaller number of patients the difference was not significant. Summarized the in- and outpatients, the proglumid-group had a healing-rate of 83%, the antacid-group of 60% (p less than 0.05). Bigger ulcers with a size more than 120 mm2 at the beginning showed a significant better healing with proglumid than with the antacid-drug (t/2 = 14.6 resp. 24.6 days). With x-ray-examination we could not find differences of healing between the two groups, but younger patients often were not examined. The symptoms of patients did not show a significant difference during the healing-course. We could not find any side-effects. Proglumid is an effective drug for the healing of chronic duodenal ulcers.

Published
1981

9. [Children with cerebral palsy].

Author

Consentius K

Subjects
Cerebral Palsy diagnosis, Cerebral Palsy rehabilitation, Child, Humans, Cerebral Palsy classification
Published
1982

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