1. Helical tomotherapy optimized planning parameters for nasopharyngeal cancer
- Author
-
Imjai Chitapanarux, K Yawichai, and Somsak Wanwilairat
- Subjects
History ,business.industry ,medicine.medical_treatment ,Pitch factor ,Patient data ,Tomotherapy ,030218 nuclear medicine & medical imaging ,Computer Science Applications ,Education ,Modulation factor ,03 medical and health sciences ,0302 clinical medicine ,Treatment plan ,030220 oncology & carcinogenesis ,medicine ,Treatment time ,Nuclear medicine ,business ,Nasopharyngeal cancer - Abstract
Helical TomoTherapy(HT) planning depends on optimize parameters including field width (FW), pitch factor (PF) and modulation factor (MF). These optimize parameters are effect to quality of plans and treatment time. The aim of this study was to find the optimized parameters which compromise between plan quality and treatment times. Six nasopharyngeal cancer patients were used. For each patient data set, 18 treatment plans consisted of different optimize parameters combination (FW=5.0, 2.5, 1.0 cm; PF=0.43, 0.287, 0.215; MF2.0, 3.0) were created. The identical optimization procedure followed ICRU83 recommendations. The average D50 of both parotid glands and treatment times per fraction were compared for all plans. The study show treatment plan with FW1.0 cm showed the lowest average D50 of both parotid glands. The treatment time increased inversely to FW. The FW1.0 cm the average treatment time was 4 times longer than FW5.0 cm. PF was very little influence on the average D50 of both parotid glands. Finally, MF increased from 2.0 to 3.0 the average D50 of both parotid glands was slightly decreased. However, the average treatment time was increased 22.28%. For routine nasopharyngeal cancer patients with HT, we suggest the planning optimization parameters consist of FW=5.0 cm, PF=0.43 and MF=2.0.
- Published
- 2016