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1. Risk assessment of Genetically Modified Organisms (GMOs)

Author

Waigmann E, Paoletti C, Davies H, Perry J, Kärenlampi S, and Kuiper H

Subjects
GM plants, GM animals, GM microorganisms, post market environmental monitoring, comparative risk assessment, Nutrition. Foods and food supply, TX341-641, Chemical technology, TP1-1185
Abstract

EFSA’s remit in the risk assessment of GMOs is very broad encompassing genetically modified plants, microorganisms and animals and assessing their safety for humans, animals and the environment. The legal frame for GMOs is set by Directive 2001/18/EC on their release into the environment, and Regulation (EC) No 1829/2003 on GM food and feed. The main focus of EFSA’s GMO Panel and GMO Unit lies in the evaluation of the scientific risk assessment of new applications for market authorisation of GMOs, and in the development of corresponding guidelines for the applicants. The EFSA GMO Panel has elaborated comprehensive guidance documents on GM plants, GM microorganisms and GM animals, as well as on specific aspects of risk assessment such as the selection of comparators. EFSA also provides special scientific advice upon request of the European Commission; examples are post-market environmental monitoring of GMOs, and consideration of potential risks of new plant breeding techniques. The GMO Panel regularly reviews its guidance documents in the light of experience gained with the evaluation of applications, technological progress in breeding technologies and scientific developments in the diverse areas of risk assessment.

Published
2012
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14. Genome sequencing and population genomic analyses provide insights into the adaptive landscape of silver birch

Author

Salojärvi, J. (Jarkko), Smolander, O.-P. (Olli-Pekka), Nieminen, K. (Kaisa), Rajaraman, S. (Sitaram), Safronov, O. (Omid), Safdari, P. (Pezhman), Lamminmäki, A. (Airi), Immanen, J. (Juha), Lan, T. (Tianying), Tanskanen, J. (Jaakko), Rastas, P. (Pasi), Amiryousefi, A. (Ali), Jayaprakash, B. (Balamuralikrishna), Kammonen, J. I. (Juhana I.), Hagqvist, R. (Risto), Eswaran, G. (Gugan), Ahonen, V. H. (Viivi Helena), Serra, J. A. (Juan Alonso), Asiegbu, F. O. (Fred O.), Barajas-Lopez, J. d. (Juan de Dios), Blande, D. (Daniel), Blokhina, O. (Olga), Blomster, T. (Tiina), Broholm, S. (Suvi), Brosche, M. (Mikael), Cui, F. (Fuqiang), Dardick, C. (Chris), Ehonen, S. E. (Sanna E.), Elomaa, P. (Paula), Escamez, S. (Sacha), Fagerstedt, K. V. (Kurt V.), Fujii, H. (Hiroaki), Gauthier, A. (Adrien), Gollan, P. J. (Peter J.), Halimaa, P. (Pauliina), Heino, P. I. (Pekka I.), Himanen, K. (Kristiina), Hollender, C. (Courtney), Kangasjärvi, S. (Saijaliisa), Kauppinen, L. (Leila), Kelleher, C. T. (Colin T.), Kontunen-Soppela, S. (Sari), Koskinen, J. P. (J. Patrik), Kovalchuk, A. (Andriy), Kärenlampi, S. O. (Sirpa O.), Kärkönen, A. K. (Anna K.), Lim, K.-J. (Kean-Jin), Leppälä, J. (Johanna), Macpherson, L. (Lee), Mikola, J. (Juha), Mouhu, K. (Katriina), Mähönen, A. P. (Ari Pekka), Niinemets, Ü. (Ülo), Oksanen, E. (Elina), Overmyer, K. (Kirk), Palva, E. T. (E. Tapio), Pazouki, L. (Leila), Pennanen, V. (Ville), Puhakainen, T. (Tuula), Poczai, P. (Peter), Possen, B. J. (Boy J. H. M.), Punkkinen, M. (Matleena), Rahikainen, M. M. (Moona M.), Rousi, M. (Matti), Ruonala, R. (Raili), van der Schoot, C. (Christiaan), Shapiguzov, A. (Alexey), Sierla, M. (Maija), Sipilä, T. P. (Timo P.), Sutela, S. (Suvi), Teeri, T. H. (Teemu H.), Tervahauta, A. I. (Arja I.), Vaattovaara, A. (Aleksia), Vahala, J. (Jorma), Vetchinnikova, L. (Lidia), Welling, A. (Annikki), Wrzaczek, M. (Michael), Xu, E. (Enjun), Paulin, L. G. (Lars G.), Schulman, A. H. (Alan H.), Lascoux, M. (Martin), Albert, V. A. (Victor A.), Auvinen, P. (Petri), Helariutta, Y. (Ykä), Kangasjärvi, J. (Jaakko), Salojärvi, J. (Jarkko), Smolander, O.-P. (Olli-Pekka), Nieminen, K. (Kaisa), Rajaraman, S. (Sitaram), Safronov, O. (Omid), Safdari, P. (Pezhman), Lamminmäki, A. (Airi), Immanen, J. (Juha), Lan, T. (Tianying), Tanskanen, J. (Jaakko), Rastas, P. (Pasi), Amiryousefi, A. (Ali), Jayaprakash, B. (Balamuralikrishna), Kammonen, J. I. (Juhana I.), Hagqvist, R. (Risto), Eswaran, G. (Gugan), Ahonen, V. H. (Viivi Helena), Serra, J. A. (Juan Alonso), Asiegbu, F. O. (Fred O.), Barajas-Lopez, J. d. (Juan de Dios), Blande, D. (Daniel), Blokhina, O. (Olga), Blomster, T. (Tiina), Broholm, S. (Suvi), Brosche, M. (Mikael), Cui, F. (Fuqiang), Dardick, C. (Chris), Ehonen, S. E. (Sanna E.), Elomaa, P. (Paula), Escamez, S. (Sacha), Fagerstedt, K. V. (Kurt V.), Fujii, H. (Hiroaki), Gauthier, A. (Adrien), Gollan, P. J. (Peter J.), Halimaa, P. (Pauliina), Heino, P. I. (Pekka I.), Himanen, K. (Kristiina), Hollender, C. (Courtney), Kangasjärvi, S. (Saijaliisa), Kauppinen, L. (Leila), Kelleher, C. T. (Colin T.), Kontunen-Soppela, S. (Sari), Koskinen, J. P. (J. Patrik), Kovalchuk, A. (Andriy), Kärenlampi, S. O. (Sirpa O.), Kärkönen, A. K. (Anna K.), Lim, K.-J. (Kean-Jin), Leppälä, J. (Johanna), Macpherson, L. (Lee), Mikola, J. (Juha), Mouhu, K. (Katriina), Mähönen, A. P. (Ari Pekka), Niinemets, Ü. (Ülo), Oksanen, E. (Elina), Overmyer, K. (Kirk), Palva, E. T. (E. Tapio), Pazouki, L. (Leila), Pennanen, V. (Ville), Puhakainen, T. (Tuula), Poczai, P. (Peter), Possen, B. J. (Boy J. H. M.), Punkkinen, M. (Matleena), Rahikainen, M. M. (Moona M.), Rousi, M. (Matti), Ruonala, R. (Raili), van der Schoot, C. (Christiaan), Shapiguzov, A. (Alexey), Sierla, M. (Maija), Sipilä, T. P. (Timo P.), Sutela, S. (Suvi), Teeri, T. H. (Teemu H.), Tervahauta, A. I. (Arja I.), Vaattovaara, A. (Aleksia), Vahala, J. (Jorma), Vetchinnikova, L. (Lidia), Welling, A. (Annikki), Wrzaczek, M. (Michael), Xu, E. (Enjun), Paulin, L. G. (Lars G.), Schulman, A. H. (Alan H.), Lascoux, M. (Martin), Albert, V. A. (Victor A.), Auvinen, P. (Petri), Helariutta, Y. (Ykä), and Kangasjärvi, J. (Jaakko)

Abstract

Silver birch (Betula pendula) is a pioneer boreal tree that can be induced to flower within 1 year. Its rapid life cycle, small (440-Mb) genome, and advanced germplasm resources make birch an attractive model for forest biotechnology. We assembled and chromosomally anchored the nuclear genome of an inbred B. pendula individual. Gene duplicates from the paleohexaploid event were enriched for transcriptional regulation, whereas tandem duplicates were overrepresented by environmental responses. Population resequencing of 80 individuals showed effective population size crashes at major points of climatic upheaval. Selective sweeps were enriched among polyploid duplicates encoding key developmental and physiological triggering functions, suggesting that local adaptation has tuned the timing of and cross-talk between fundamental plant processes. Variation around the tightly-linked light response genes PHYC and FRS10 correlated with latitude and longitude and temperature, and with precipitation for PHYC. Similar associations characterized the growth-promoting cytokinin response regulator ARR1, and the wood development genes KAK and MED5A.

Published
2017

16. MEIC Evaluation of Acute Systemic Toxicity: Part VI. The Prediction of Human Toxicity by Rodent LD50 Values and Results From 61 In Vitro Methods

Author

Ekwall, B., Barile, F. A., Argelia Castano, Clemedson, C., Clothier, R. H., Dierickx, P., Ferro, M., Fiskesjö, G., Garza-Ocañas, L., Gómez-Lechón, M. J., Gülden, M., Hall, T., Isomaa, B., Kahru, A., Kerszman, G., Kristen, U., Kunimoto, M., Kärenlampi, S., Lewan, L., Loukianov, A., Ohno, T., Persoone, G., Romert, L., Sawyer, T. W., Shrivastava, R., Segner, H., Stammati, A., Tanaka, N., Valentino, M., Walum, E., and Zucco, F.

Published
2015

17. Safety and efficacy of Danisco Xylanase G/L (endo-1,4-beta-xylanase) as a feed additive for chickens for fattening, laying hens and ducks for fattening. Scientific Opinion of the Panel on Additives and Products or Substances used in Animal Feed and of the Panel on Genetically Modified Organisms:(Question No EFSA-Q-2006-137)

Author

Bories, G., Brantom, P., Brufau de Barberá, J., Chesson, A, Cocconcelli, P. S., Debski, B., Dierick, N., Franklin, A., Gropp, J., Halle, I., Hogstrand, C., de Knecht, J., Leng, L., Haldorsen, A.-K. L., Mantovani, A., Mézes, M., Nebbia, C., Rambeck, W., Rychen, G., von Wright, A., Wester, P., Andersson, H. C., Arpaia, S., Bartsch, D., Casacuberta, J., Davies, H., De Loose, M., Hendriksen, N. B., Herman, L., Kärenlampi, S., Kiss, J., Kryspin-Sørensen, I., Kuiper, H. A., Nes, I., Panopoulos, N., Perry, J., Pöting, A., Schiemann, J., Seinen, W., Sweet, J. B., and Wal, J. M.

Published
2007

19. Opinion of the Scientific Panel on Genetically Modified Organisms on an application (Reference EFSA-GMO-NL-2005-18) for the placing on the market of the glufosinate tolerant soybean A2704-12, for food and feed uses, import and processing under Regulation (EC) No 1829/2003 from Bayer CropScience:(Question No EFSA-Q-2005-174)

Author

Andersson, H. C., Arpaia, S., Bartsch, D., Casacuberta, J., Davies, H., Einspanier, R., Herman, L., De Loose, M., Hendriksen, N. B., Kärenlampi, S., Kiss, J., Kryspin-Sørensen, I., Kuiper, H., Nes, I., Panopoulos, N., Perry, J., Pöting, A., Schiemann, J., Seinen, W., Sweet, J., and Wal, J-M.

Published
2007

20. Opinion of the Scientific Panel on genetically Modified Organisms on an application (Reference EFSA-GMO-NL-2005-12) for the placing on the market of insect-resistant genetically modified maize 59122, for food and feed uses, import and processing under Regulation (EC) No 1829/2003, from Pioneer Hi-Bred International, Inc. and Mycogen Seeds, c/o Dow Agrosciences LLC:(Question No EFSA-Q-2005-045)

Author

Andersson, H. C., Arpaia, S., Bartsch, D., Casacuberta, J., Davies, H., Herman, L., De Loose, M., Hendriksen, N. B., Kärenlampi, S., Kiss, J., Kryspin-Sørensen, I., Kuiper, H., Nes, I., Panopoulos, N., Perry, J., Pöting, A., Schiemann, J., Seinen, W., Sweet, J., and Wal, J.-M.

Published
2007

21. Opinion of the Scientific Panel on Additives and Products or Substances used in Animal Feed and the Scientific Panel on genetically Modified Organisms on the safety and efficacy of the enzyme preparation Rovabio TM PHY AP/LC (3-phytase) as feed additive for chickens for fattening, laying hens, piglets and pigs for fattening in accordance with Regulation (EC) No 1831/2003:(Question No EFSA-Q-2005-281)

Author

Bories, G., Brantom, P., Brufau de Barberá, J., Chesson, A, Cocconcelli, P. S., Debski, B., Dierick, N., Franklin, A., Gropp, J., Halle, I., Hogstrand, C., de Knecht, J., Leng, L., Haldorsen, A.-K. L., Mantovani, A., Mézes, M., Nebbia, C., Rambeck, W., Rychen, G., von Wright, A., Wester, P., Andersson, H. C., Arpaia, S., Bartsch, D., Casacuberta, J., Davies, H., De Loose, M., Einspanier, R., Hendriksen, N. B., Herman, L., Kärenlampi, S., Kiss, J., Kryspin-Sørensen, I., Kuiper, H. A., Nes, I., Panopoulos, N., Perry, J., Pöting, A., Schiemann, J., Seinen, W., Sweet, J. B., and Wal, J.-M.

Published
2007

22. Opinion of the Scientific Panel on Genetically Modified Organisms on an application (Reference EFSA-GMO-NL-2005-13) for the placing on the market of glufosinate-tolerant genetically modified LLCotton25, for food and feed uses, and import and processing under Regulation (EC) No 1829/2003 from Bayer CropScience:(Question No EFSA-Q-2005-047)

Author

Andersson, H. C., Arpaia, S., Bartsch, D., Casacuberta, J., Davies, H., Einspanier, R., Herman, L., De Loose, M., Hendriksen, N. B., Kärenlampi, S., Kiss, J., Kryspin-Sørensen, I., Kuiper, H., Nes, I., Panopoulos, N., Perry, J., Pöting, A., Schiemann, J., Seinen, W., Sweet, J., and Wal, J.-M.

Published
2006

23. Opinion of the Scientific Panel on Genetically Modified Organisms on an application (Reference EFSA-GMO-UK-2004-08) for the placing on the market of products produced from glyphosate-tolerant genetically modified sugar beet H7-1, for food and feed uses, under Regulation (EC) No 1829/2003 from KWS SAAT AG and Monsanto. (Question No EFSA-Q-2004-164)

Author

Andersson, H. C., Arpaia, S., Bartsch, D., Casacuberta, J., Davies, H., Einspanier, R., De Loose, M., Hendriksen, N. B., Herman, L., Kärenlampi, S. O., Kiss, J., Kryspin-Sørensen, I., Kuiper, H., Nes, I., Panopoulos, N., Perry, J., Pöting, A., Schiemann, J., Seinen, W., Sweet, J., and Wal, J.-M.

Published
2006

24. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the notification (Reference C/SE/96/3501) for the placing on the market of genetically modfied potato EH92-527-1 with altered starch composition, for cultivation and production of starch, under Part C of Directive 2001/18/EC from BASF Plant Science:(Question No EFSA-Q-2005-023)

Author

Andersson, C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2006

25. Opinion of the Scientific Panel on Genetically Modified Organisms on the Post Market Environmental Monitoring (PMEM) of genetically modified plants:(Question No EFSA-Q-2004-061)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., DeLoose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2006

26. Guidance document of the Scientific Panel on Genetically Modified Organisms for renewal of authorisations of existing GMO products lawfully placed on the market, notified according to Articles 8 and 20 of regulation (EC) No 1829/2003. (Question No EFSA-Q-2003-005C)

Author

Andersson, H. C., Arpaia, S., Bartsch, D., Casacuberta, J., Davies, H., Einspanier, R., Herman, L., De Loose, M., Hendriksen, N. B., Kärenlampi, S., Kiss, J., Kryspin-Sørensen, I., Kuiper, H., Nes, I., Panopoulos, N., Perry, J., Pöting, A., Schienmann, J., Seinen, W., Sweet, J., and Wal, J.-M.

Published
2006

27. Guidance document of the Scientific Panel on genetically modified organisms for the risk assessment of genetically modified plants and derived food and feed. (Question no EFSA-Q-2003-005)

Author

Andersson, C., Bartsch, D., Buhk, H. J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O'Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2006

28. Guidance document of the Scientific Panel on Genetically Modified Organisms for renewal of authorisations of existing GMO products lawfully placed on the market, notified according to Articles 8 and 20 of Regulation (EC) No 1829/2003

Author

Andersson, H. C., Arpaia, S., Bartsch, D., Casacuberta, J., Davies, H., Einspanier, R., Herman, L., De Loose, M., Hendriksen, N. B., Kärenlampi, S., Kiss, J., Kryspin-Sørensen, I., Kuiper, H., Nes, I., Panopoulos, N., Perry, J., Pöting, A., Schiemann, J., Seinen, W., Sweet, J., and Wal, J. M.

Published
2006

29. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the safeguard clause invoked by Hungary according to Article 23 of Directive 2001/18/EC (Question No EFSA-Q-2005-055)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2005

30. Opinion of the Scientific Panel on Genetically Modified Organisms on an application (Reference EFSA-GMO-BE-2004-07) for the placing on the market of insect-protected glyphosate-tolerant genetically modified maize MON863 X MON 810 X NK603, for food and feed uses, and import and processing under Regulation (EC) No 1829/2003 from Mosanto (Question No EFSA-Q-2004-159)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J-M.

Published
2005

31. Opinion of the Scientific Panel on Genetically Modified Organisms on an application (Reference EFSA-GMO-UK-2004-06) for the placing on the market of insect-protected glyphosate-tolerant genetically modified maize MON863 X NK603, for food and feed uses, and import and processing under Regulation (EC) No 1829/2003 from Monsanto (Question No EFSA-Q-2004-154)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2005

32. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the notification (Reference C/ES/01/01) for the placing on the market of insect-tolerant genetically modified maize 1507 for import, feed and industrial processing and cultivation, under Part C of Directive 2001/18/EC from Pioneer Hi-Bred International/Mycogen Seeds (Question No EFSA-Q-2004-072)

Author

Anderson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2005

33. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the Notification (Reference C/DE/02/9) for the placing on the market of insect-protected genetically modified maize MON 863 X MON 810, for import and processing, under Part C of Directive 2001/18/EC from Monsanto (Question No EFSA-Q-2003-089)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2005

34. Opinion of the Scientific Panel on Genetically Modified Organisms on an application (Reference EFSA-GMO-DE-2004-03) for the placing on the market of insect-protected genetically modified maize MON 863 X MON 810, for food and feed use, under Regulation (EC) No 1829/2003 from Monsanto (Question No EFSA-Q-2004-112)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2005

35. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the notification (Reference C/F/96/05.10) for the placing on the market of insect resistant genetically modified maize Bt11, for cultivation, feed and industrial processing, under Part C of Directive 2001/18/EC from Syngenta Seeds (Question No EFSA-Q-2004-012)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O`Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2005

36. Opinion of the Scientific Panel on Genetically Modified Organisms on an application (reference EFSA-GMO-NL-2004-02) for the placing on the market of insect-tolerant genetically modified maize 1507, for food use, under Regulation (EC) No 1829/2003 from Pioneer Hi-Bred International/Mycogen Seeds (Question no EFSA-Q-2004-087)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Heritage, J., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2005

37. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the Greek invoke of Article 23 of Directive 2001/18/EC1 (Question No EFSA-Q-2004-062)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Krypsin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2004

38. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the notification (Reference C/NL/00/10) for the placing on the market of insect-tolerant genetically modified maize 1507, for import and processing, under Part C of Directive 2001/18/EC from Pioneer Hi-Bred International/Mycogen Seeds.(Question No EFSA-Q-2004-011):Opinion adopted on 24 September 2004

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Kärenlampi, S., Krypsin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2004

39. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the safety of foods and food ingredients derived from insect-protected genetically modified maize MON 863 and MON 863 x MON 810, for which a request for placing on the market was submitted under Article 4 of the Novel Food Regulation (EC) No 258/97 by Monsanto (Question No EFSA-Q-2003-121):Opinion adopted on 2 April 2004

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Abstract

EFSA=European Food Safety Authority

Published
2004

40. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the Notification (Reference C/NL/98/11) for the placing on the market of herbicide-tolerant oilseed rape GT73, for import and processing, under Part C of Directive 2001/18/EC from Monsanto (Question No EFSA-Q-2003-078)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2004

41. Opinion of the Scientific Panel on Genetically Modified Organisms on the use of antibiotic resistance genes as marker genes in genetically modified plants (Question No EFSA-Q-2003-109):Opinion adopted on 2 April 2004

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Krypsin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Abstract

EFSA=European Food Safety Authority

Published
2004

42. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the Austrian invoke of Article 23 of Directive 2001/18/EC1 (Question No EFSA-Q-2004-062)

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Krypsin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2004

43. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the Notification (Reference C/DE/02/9) for the placing on the market of insect-protected genetically modified maize MON 863 and MON 863 x MON 810, for import and processing, under Part C of Directive 2001/18/EC from Monsanto (Question No EFSA-Q-2003-089):Opinion adopted on 2 April 2004

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Abstract

EFSA=European Food Safety Authority

Published
2004

44. Guidance document of the scientific panel on genetically modified organisms for the risk assessment of genetically modified plants and derived food and feed:(Question No EFSA-Q-2003-005)

Author

Andersson, C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O´Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Published
2004

46. Opinion of the Scientific Panel on Genetically Modified Organisms on a question from the Commission related to the Austrian notification of national legislation governing GMOs under article 95(5) of the Treaty

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., Loose, M. De, Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O'Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Abstract

Opinion adopted on 4 July 2003 (Question No EFSA-Q-2003-001); EFSA=European Food Safety Authority

Published
2003

47. Use of the cDNA microarray technology in thesafety assessment of GM food plants

Author

Pedersen, Jan W., Knudsen, Ib, Eriksen, Folmer Damsted, Kärenlampi, S., Mikalsen, A., Hammerling, U., Kok, E., Bak, S., and Nielsen, Henrik Bjørn

Subjects
fungi
Abstract

This report focuses on new analytical approaches that might give more insight into possible changes in a genetically modified plant. Primarily the focus is on the new DNA microarray technique but also proteomics and metabolomics are discussed.The report describes the new techniques and evaluates the potentials and applications of the techniques as a tool in safety assessment of genetically modified plants. The background for this evaluation of new techniques is that some concerns have been raised about the targeted approach used for evaluating the health risk of GM-plants. Today, an important part of the safety evaluation of novel GMO-derived plant products is an elaborate comparative compositional analysis, including analyses of key nutrients and anti-nutrients, of the newly developed plant variety and of the `traditional¿ counterpart that is already on the market. Although this has been considered as an adequate procedure for evaluating the safety of GM plants, new analytical approaches may be useful in this safety assessment procedure and therefore need be evaluated.

Published
2003

48. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the safety of foods and food ingredients derived from herbicide-tolerant genetically modified maize NK603, for which a request for placing on the market was submitted under Article 4 of the Novel Food Regulation (EC) No 258/97 by Monsanto:Opinion adopted on 25 November 2003

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., Loose, M. D., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O'Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J.-D., and Wal, J.-M.

Abstract

EFSA=European Food Safety Authority

Published
2003

49. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to the Notification (Reference CE/ES/00/01) for the placing on the market of herbicide-tolerant genetically modified maize NK603, for import and processing, under Part C of Directive 2001/18/EC from Monsanto:Opinion adopted on 25 November 2003

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., Loose, M. D., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O'Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Abstract

EFSA=European Food Safety Authority

Published
2003

50. Opinion of the Scientific Panel on Genetically Modified Organisms on a request from the Commission related to guidance notes supplementing Part B of Annex II to Council Directive 90/219/EEC, as amended by Directive 98/81/EC, on the contained use of genetically modified micro-organisms:Opinion adopted on 11 December 2003

Author

Andersson, H. C., Bartsch, D., Buhk, H.-J., Davies, H., De Loose, M., Gasson, M., Hendriksen, N. B., Hill, C., Kärenlampi, S., Kryspin-Sørensen, I., Kuiper, H., Nuti, M., O'Gara, F., Puigdomenech, P., Sakellaris, G., Schiemann, J., Seinen, W., Sessitsch, A., Sweet, J., van Elsas, J. D., and Wal, J.-M.

Abstract

EFSA=European Food Safety Authority

Published
2003

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