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310 results on '"Kähler, Georg"'

8. Implementation of endoscopic submucosal dissection in Europe: survey after 10 ESD Expert Training Workshops, 2009 to 2018

Author

Halm, Ulrich, Schulz, Heinrich, Chabrun, Edouard, Cholet, Franck, Thorlacius, Henrik, Dumoulin, Franz-Ludwig, Herreros de Tejada, Alberto, Łozinski, Cezary, Caillol, Fabrice, Spychalski, Michal, Santos-Antunes, João C., Lutz, Manfred, Bermoser, Katrin, Schäfer, Andreas, Krankenhaus, Alfried-Krupp, LeBaleur, Yann, Jacob, Harold, Allgaier, Hans-Peter, Kleber, Gerhard, Steinbrück, Ingo, Tringali, Alberto, Flatz, Thomas, Österreicher, Christian, Glas, Anton, Schroder, Robert, Lutterer, Achim, Wedi, Edris, Anzinger, Michael, Boger, Philip, Suchánek, Stepan, Laquière, Arthur, Rajkumar, Sarveson, Rupinski, Maciej, Jue, Terry, Barawi, Mohamed, Schlag, Christoph, Möschler, Oliver, Sferrazza, Sandro, Pekarek, Boris, Poyrazoglu, Orhan Kursat, Baran, Bulent, Mayer, Andreas, Tribl, Barbara, Goetz, Martin, Plamenig, Dieter, Pickartz, Tilman, Hayward, Chris, Grünhage, Frank, Qutob, Tarek, Seerden, Tom, Schmitz, Volker, Wiest, Reiner, Hoffman, Arthur, Horvath, Henrik, Viale, Edi, LaRoche, Michaela, Peveling-Oberhag, Jan, Aerts, Maridi, Gal, Eyal, Doykov, Daniel, Allerstorfer, David, Bodlaj, Gerd, Maskelis, Romualdas, Vassiljeva, Varvara, Kapetanakis, Nikos, Appenrodt, Beate, Moura, Miguel, Bastiaansen, Barbara A., Barsic, Neven, Zimmer, Vinzent, Oyama, Tsuneo, Yahagi, Naohisa, Ponchon, Thierry, Kiesslich, Tobias, Wagner, Andrej, Toyonaga, Takashi, Uraoka, Toshio, Takahashi, Akiko, Ziachehabi, Alexander, Neureiter, Daniel, Fuschlberger, Maria, Schachinger, Franz, Seifert, Hans, Kaehler, Georg, Mitrakov, Alexandr, Kantsevoy, Sergey V., Messmann, Helmut, Hochberger, Juergen, and Berr, Frieder

Published
2023
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9. Outcomes of rescue procedures in the management of locally recurrent ampullary tumors: A Pancreas 2000/EPC study

Author

Karam, Elias, Hollenbach, Marcus, Ali, Einas Abou, Auriemma, Francesco, Gulla, Aiste, Heise, Christian, Regner, Sara, Gaujoux, Sébastien, Regimbeau, Jean M., Kähler, Georg, Seyfried, Steffen, Vaillant, Jean C., De Ponthaud, Charles, Sauvanet, Alain, Birnbaum, David, Regenet, Nicolas, Truant, Stéphanie, Pérez-Cuadrado-Robles, Enrique, Bruzzi, Matthieu, Lupinacci, Renato M., Brunel, Martin, Belfiori, Giulio, Barbier, Louise, Salamé, Ephrem, Souche, Francois R., Schwarz, Lilian, Maggino, Laura, Salvia, Roberto, Gagniére, Johan, Del Chiaro, Marco, Leung, Galen, Hackert, Thilo, Kleemann, Tobias, Paik, Woo H., Caca, Karel, Dugic, Ana, Muehldorfer, Steffen, Schumacher, Brigitte, and Albers, David

Published
2023
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13. Onset time and characteristics of post-procedural bleeding after endoscopic resection of colorectal lesions: a multicenter retrospective study

Author

Xiao, Qiyun, primary, Eckardt, Maximilian, additional, Mohamed, Awsan, additional, Ernst, Helmut, additional, Behrens, Alexander, additional, Homann, Nils, additional, Hielscher, Thomas, additional, Kähler, Georg, additional, Ebert, Matthias, additional, Belle, Sebastian, additional, and Zhan, Tianzuo, additional

Published
2023
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19. Onset Time and Characteristics of Postprocedural Bleeding after Endoscopic Resection of Colorectal Lesions: A Multicenter Retrospective Study.

Author

Xiao, Qiyun, Eckardt, Maximilian, Mohamed, Awsan, Ernst, Helmut, Behrens, Alexander, Homann, Nils, Hielscher, Thomas, Kähler, Georg, Ebert, Matthias, Belle, Sebastian, and Zhan, Tianzuo

Subjects
ENDOSCOPIC surgery, GASTROINTESTINAL hemorrhage, LOGISTIC regression analysis, HEMORRHAGE, PLATELET aggregation inhibitors
Abstract

Introduction: Postprocedural bleeding is a major adverse event after endoscopic resection of colorectal lesions, but the optimal surveillance time after endoscopy is unclear. In this study, we determined onset time and characteristics of postprocedural bleeding events. Methods: We retrospectively screened patients who underwent endoscopic resection of colorectal lesions at three German hospitals between 2010 and 2019 for postprocedural bleeding events using billing codes. Only patients who required re-endoscopy were included for analysis. For identified patients, we collected demographic data, clinical courses, characteristics of colorectal lesions, and procedure-related variables. Factors associated with late-onset bleeding were determined by univariate and multivariate logistic regression analysis. Results: From a total of 6,820 patients with eligible billing codes, we identified 113 cases with postprocedural bleeding after endoscopic mucosal (61.9%) or snare resection (38.1%) that required re-endoscopy. The median size of the culprit lesion was 20 mm (interquartile range 14–30 mm). The median onset time of postprocedural bleeding was day 3 (interquartile range: 1–6.5 days), with 48.7% of events occurring within 48 h. Multivariate logistic regression analysis demonstrates that a continued intake of antiplatelet drugs (OR: 3.98, 95% CI: 0.89–10.12, p = 0.025) and a flat morphology of the colorectal lesion (OR: 2.98, 95% CI: 1.08–8.01, p = 0.031) were associated with an increased risk for late postprocedural bleeding (>48 h), whereas intraprocedural bleeding was associated with a decreased risk (OR: 0.12, 95% CI: 0.04–0.50, p = 0.001). Conclusion: Significant postprocedural bleeding can occur up to 18 days after endoscopic resection of colorectal lesions, but was predominantly observed within 48 h. Continued intake of antiplatelet drugs and a flat polyp morphology are associated with risk for late postprocedural bleeding. [ABSTRACT FROM AUTHOR]

Published
2024
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47. Transanal endoscopic microsurgical submucosal dissection: Are there advantages over conventional ESD?

Author

Kouladouros, Konstantinos, Warkentin, Viktor, and Kähler, Georg

Subjects
RECTAL surgery, BIOLOGICAL models, EXPERIMENTAL design, RECTUM tumors, MICROSURGERY, ANIMAL experimentation, TREATMENT duration, SWINE, COMPARATIVE studies, DESCRIPTIVE statistics, ENDOSCOPIC gastrointestinal surgery, PROCTOSCOPY
Abstract

Transanal endoscopic microsurgical submucosal dissection (TEM-ESD) is a technique that has been recently described for the treatment of large rectal adenomas and early rectal cancer. The purpose of our study is to compare TEM-ESD with flexible endoscopic submucosal dissection (ESD) in an experimental, ex vivo porcine model. We used TEM-ESD and flexible ESD to resect a total of 100 standardized 4 × 4cm lesions in an ex vivo porcine stomach model, performing 50 resections with each technique. Total procedure time, en bloc resection rate, injuries of the muscularis propria, perforation rate and learning curve were analysed. TEM-ESD was associated with a significantly shorter total procedure time in comparison to ESD (19 min vs. 33 min, p <.001). The rates of en bloc resection, injury of the muscularis propria layer, and perforation were the same in both groups. The learning curve of TEM-ESD was shallower than that of ESD. TEM-ESD showed an advantage over ESD in terms of procedure time and learning curve, with similar en bloc resection rates and safety profile in our experimental model. [ABSTRACT FROM AUTHOR]

Published
2022
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