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Every human body is made up of billions of cells, and every cell consists of thousands of microscopic structures. Thanks to the presence of the cytoskeleton, which is built by microfilaments, microtubules, and intermediate filaments, cells are able to fulfill their main function. Dozens of genes encode a large family of cytoskeletal proteins, which form 10-nanometer-long microfilaments, called cytokeratins. The study was carried out on seven mature human placentas without significant pathology - all eligible mothers were healthy. The collection of basic anthropometric data preceded the dissection of the placentas. Paraffin blocks were made in the usual manner, and hematoxylin and eosin-stained slides were made afterward. Immunohistochemical reactions were performed and the expression of the studied markers was evaluated independently by two observers. Evaluation of microscopic material revealed the absence of expression of antibodies for cytokeratin 5/6 in placental tissues. Moreover, strong expression of cytokeratin 7 was demonstrated in the villi trophoblast in all types of villi. Immunohistochemical reactions were observed in the mesenchyme within the blood vessel wall, as well as in the extravascular tissue. The human placenta is an organ that only exists during the intrauterine period of human development and undergoes rapid changes and dynamic growth during pregnancy. These types of processes define selected placental cells as ‘pseudo-tumorigenic tissue’ because of the numerous similarities trophoblast cells have to tumor cells. The use of tissue microarray (TMA) in combination with immunohistochemistry (IHC) may be a valuable approach to validate the predictive and diagnostic utility of various biomarkers in non-cancerous tissues like placental tissue.

Recent scientific evidence suggests that one of the causes of myofascial pain syndromes responsible for the occurrence of chronic headaches, among other things, may be increased or impaired with trigger point therapy. This paper presents the results of a non-systematic literature review on trigger point therapy. The analysis shows a clear increase in scientific interest in invasive trigger point pain treatment techniques. Invasive therapy consists primarily of the use of injections and dry needling. Injections of anesthetics or botulinum toxin are methods that, in addition to their possible therapeutic effect, may carry side effects. In contrast, dry needling does not have a fully scientifically-proven effect. Recent scientific data also indicates that the aforementioned method may have a limited clinical effect. The performed analysis did not demonstrate a significant advantage in invasive techniques over typical non-invasive techniques. It is therefore necessary to design randomized multi-center clinical trials to definitively verify the efficacy of these techniques in the treatment of tension-type trigger point-dependent myofascial pain.

The care of historical collections in anatomical museums is a highly specialized subject requiring advanced knowledge. When searching for practical information on this subject, the authors were not able to find appropriate literature based on scientific research. The absence of this literature is probably due to the specialized nature of the subject and the poorly defined classification of this type of museum. The purpose of this study is to conduct a systematic literature review to identify (i) the current state of knowledge of anatomical museology and (ii) the nature and determinants of ongoing research on anatomical museum objects.A systematic search of the main electronic databases (PubMed, Google Scholar, Scopus) was conducted to identify relevant studies. The records retrieved were categorized according to thematic similarity and scientific content. Based on these groupings, statistics were created based on the number of eligible papers in each particular group.61 % of the papers retrieved addressed the history, social issues, or related aspects of contemporary museology; 8 % were technical papers; and 31 % research papers, of which only 8 % were focused on the museum object as the topic of the research. The paper retrieved showed a predominance of works in cultural studies, with surprisingly few applicable to museum practice. Furthermore, there was a lack of consensus in the literature regarding the classification of anatomical museums.Anatomical museology is a poorly defined concept in the scientific literature and it is a rare topic in contemporary work by anatomical practitioners. The literature review revealed that the debate about the fate of anatomical museums encompasses a broad spectrum of diverse, often disparate scientific fields as well as economic factors that influence the present status and future of these institutions. For these reasons, museum object research is problematic in design, may not be considered worthwhile, or is unattractive from an institutional perspective. The literature survey showed that there is a paucity of work in the available modern literature that provides significant support for museum anatomists.

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Detailed knowledge of the anatomy of human placenta vessels is clinically essential and requires the use of many different anatomical and histological techniques. One of the interesting methods of visualising vessels is the corrosion technique. It enables spatial visualisation of the vascular network of the analysed organ. The authors present a developed, own method of preparing the corrosive preparations from human placenta. They underline the advantages and disadvantages of this technique. They describe solutions aimed at reducing the costs of the process. They show that corrosion technology enables relatively fast and inexpensive visualisation of arterial and venous vessels of the human placenta.