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16 results on '"Junemann, Carola"'

6. Spatial Relationships of MR Imaging and Positron Emission Tomography with Phenotype, Genotype and Tumor Stem Cell Generation in Glioblastoma Multiforme

Author

Schiffer, Davide, primary, Valentini, Consuelo, additional, Melcarne, Antonio, additional, Mellai, Marta, additional, Prodi, Elena, additional, Carrara, Giovanna, additional, Denysenko, Tetyana, additional, Junemann, Carola, additional, Casalone, Cristina, additional, Corona, Cristiano, additional, Caldera, Valentina, additional, Annovazzi, Laura, additional, Piazzi, Angela, additional, Cassoni, Paola, additional, Senetta, Rebecca, additional, Fania, Piercarlo, additional, and Cistaro, Angelina, additional

Published
2014
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8. Management of Extramedullary Intradural Spinal Tumors: The Impact of Clinical Status, Intraoperative Neurophysiological Monitoring and Surgical Approach on Outcomes in a 12-Year Double-Center Experience

Author

Cofano, Fabio, primary, Giambra, Carlotta, additional, Costa, Paolo, additional, Zeppa, Pietro, additional, Bianconi, Andrea, additional, Mammi, Marco, additional, Monticelli, Matteo, additional, Di Perna, Giuseppe, additional, Junemann, Carola Vera, additional, Melcarne, Antonio, additional, Massaro, Fulvio, additional, Ducati, Alessandro, additional, Tartara, Fulvio, additional, Zenga, Francesco, additional, and Garbossa, Diego, additional

Published
2020
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11. Conscious Sedation with Dexmedetomidine in Awake Surgery

Author

Altieri, Roberto, primary, Zenga, Francesco, additional, Melcarne, Antonio, additional, Junemann, Carola, additional, Faccoli, Emanuela, additional, Rivera, Alessandro, additional, Atlante, Sante, additional, Lavorato, Andrea, additional, Palmieri, Giuseppe, additional, Minardi, Massimiliano, additional, Cofano, Fabio, additional, Ducati, Alessandro, additional, Garbossa, Diego, additional, and Savastano, Riccardo, additional

Published
2018
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12. Spatial Relationships of MR Imaging and Positron Emission Tomography with Phenotype, Genotype and Tumor Stem Cell Generation in Glioblastoma Multiforme

Author

Schiffer, Davide, Valentini, Consuelo, Melcarne, Antonio, Mellai, Marta, Prodi, Elena, Carrara, Giovanna, Denysenko, Tetyana, Junemann, Carola, Casalone, Cristina, Corona, Cristiano, Caldera, Valentina, Annovazzi, Laura, Piazzi, Angela, Cassoni, Paola, Senetta, Rebecca, Fania, Piercarlo, Cistaro, Angelina, Schiffer, Davide, Valentini, Consuelo, Melcarne, Antonio, Mellai, Marta, Prodi, Elena, Carrara, Giovanna, Denysenko, Tetyana, Junemann, Carola, Casalone, Cristina, Corona, Cristiano, Caldera, Valentina, Annovazzi, Laura, Piazzi, Angela, Cassoni, Paola, Senetta, Rebecca, Fania, Piercarlo, and Cistaro, Angelina

Published
2014
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13. Expansive Masses Arising From The Clivus: The Role Of FDG-PET/CT In The Metabolic Assessment Of Skeletal Lesions

Author

Cistaro, Angelina, Durando, Sabina, Pazè, Francesco, Limberti, Andrea, Cogoni, Maurizio, Junemann, Carola, Morra, Isabella, Valentini, Maria Consuelo, Cistaro, Angelina, Durando, Sabina, Pazè, Francesco, Limberti, Andrea, Cogoni, Maurizio, Junemann, Carola, Morra, Isabella, and Valentini, Maria Consuelo

Abstract

A patient with neurological symptoms underwent CT scan that showed a sellar and suprasellar mass with bone erosions, involving especially the clivus and the right petrous apex. The first diagnostic hypothesis was chordoma in relation to the mass position. The MRI showed a solid well-enhancing mass; moreover another circumscribed lesion, with similar signal pattern, was found in the left mandibular condyle. the signal and the presence of another lesion did not agree with diagnosis of chordoma. FDG-PET/CT study showed multiple pathological uptakes suggesting a metastatic disease. A trans-sphenoidal excisional biopsy was performed and the histopathological analysis showed a population of cells consistent with a plasmacell tumor, confirmed by the presence of a monoclonal gammopathy on blood analysis. Our case suggests that FDG-PET/CT can modify the diagnostic and therapeutic procedures in myeloma, by evaluating the bone marrow involvement.

Published
2009

14. Different Aquaporin-4 Expression in Glioblastoma Multiforme Patients with and without Seizures

Author

Isoardo, Gianluca, primary, Morra, Isabella, additional, Chiarle, Giulia, additional, Audrito, Valentina, additional, Deaglio, Silvia, additional, Melcarne, Antonio, additional, Junemann, Carola, additional, Naddeo, Michele, additional, Cogoni, Maurizio, additional, Valentini, Maria Consuelo, additional, Limberti, Andrea, additional, Faccani, Federico, additional, Malavasi, Fabio, additional, and Faccani, Giuliano, additional

Published
2012
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16. Effects of Levetiracetam and Lacosamide on survival and seizure control in IDH-wild type glioblastoma during temozolomide plus radiation adjuvant therapy.

Author

Bianconi A, Koumantakis E, Gatto A, Zeppa P, Saaid A, Nico E, Bruno F, Pellerino A, Rizzo F, Junemann CV, Melcarne A, Garbossa D, Dalmasso P, and Cofano F

Abstract

Introduction: There are no clear indications for the best choice of anti-seizure medications to control brain tumor related epilepsy. In vitro studies have shown an antitumoral effect of Levetiracetam and Lacosamide on glioblastoma IDH-wild type., Research Question: This study investigates whether the use of levetiracetam and/or lacosamide impacts survival rates. The secondary aim was to evaluate the efficacy of both ASMs in controlling seizures., Materials and Methods: In this observational retrospective single-cohort study, patients underwent chemoradiation protocol after GBM surgery. They were grouped as follows: (1) use of levetiracetam, (2) use of lacosamide, (3) simultaneous use of levetiracetam and lacosamide, (4) no ASM usage. Survival curves were plotted using the Kaplan-Meier method coupled with a log-rank test for difference assesments. To evaluate the pharmacological efficacy of post-operative seizure control, a negative binomial regression was conducted., Results: The study included 272 patients, 174 of which underwent adjuvant chemoradiation treatment. Patients without ASM therapy had a non-significant longer median OS (compared to the other groups (log-rank = 0.37). The IRR of seizure relapse was 2.57 (p = 0.007) times higher in lacosamide users, and MGMT promoter methylation demonstrated a protective effect against postoperative seizure onset (p = 0.05), regardless of the aforementioned confounding factors., Discussion and Conclusions: In patients diagnosed with GBM IDH-WT undergoing chemoradiation therapy, the use of levetiracetam or lacosamide for controlling BTRE does not seem to modify survival. Lacosamide users exhibited a higher IRR of postoperative seizures compared to levetiracetam users, and MGMT promoter methylation appears to be a protective factor., (© 2024 The Authors.)

Published
2023
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