Search

To evaluate the association between IL-6 in prostatic tissue/blood sample and BPH-LUTS, so as to preliminarily discover an indicator of inflammation that could show the severity of LUTS.The prostatic tissues and blood samples were collected from 56 patients who underwent transurethral plasmakinetic resection of the prostate (TUPKRP). The association between IL-6 detected on prostatic tissues/blood sample and LUTS parameters, including international prostate symptom score (IPSS), peak flow rate (QThe TPSA and prostate volume (PV) were found to be higher in the inflammation group (p=0.021, 0.036). There was a positive association between prostate tissue inflammation and LUTS ([IPSS, storage symptoms score (SSS), voiding symptoms score (VSS), p0.05], [QIL-6 expression in prostatic tissue is associated with storage IPSS, suggesting chronic inflammation might contribute to storage LUTS.

Recent advances in pretraining language models have obtained state-of-the-art results in various natural language processing tasks. However, these huge pretraining language models are difficult to be used in practical applications, such as mobile devices and embedded devices. Moreover, there is no pretraining language model for the chemical industry. In this work, we propose a method to pretrain a smaller language representation model of the chemical industry domain. First, a huge number of chemical industry texts are used as pretraining corpus, and nontraditional knowledge distillation technology is used to build a simplified model to learn the knowledge in the BERT model. By learning the embedded layer, the middle layer, and the prediction layer at different stages, the simplified model not only learns the probability distribution of the prediction layer but also learns the embedded layer and the middle layer at the same time, to acquire the learning ability of BERT model. Finally, it is applied to the downstream tasks. Experiments show that, compared with the current BERT model distillation method, our method makes full use of the rich feature knowledge in the middle layer of the teacher model while building a student model based on the BiLSTM architecture, which effectively solves the problem that the traditional student model based on the transformer architecture is too large and improves the accuracy of the language model in the chemical domain.

Duodenal bulb adenocarcinoma is an extremely rare malignancy in the alimentary tract which has a low incidence rate and nonspecific symptoms. It is difficult to diagnose early, and the misdiagnosis rate is high. CT, MRI, upper gastrointestinal endoscopy, and other advanced imaging modalities should be combined to make a comprehensive evaluation. The diagnostic confirmation of this tumor type mainly depends on the pathological examination. The combination of surgery with other treatment modalities is effective. A review of reports on duodenal bulb adenocarcinoma with chemotherapy revealed 6 cases since 1990. However, there are few reports on neoadjuvant chemotherapy for the disease. In this report, preoperative S-1 in combination with oxaliplatin neoadjuvant chemotherapy achieved a complete pathological response in the treatment of duodenal bulb adenocarcinoma. Neoadjuvant chemotherapy shows a better clinical efficacy in the treatment of duodenal bulb adenocarcinoma, but its value needs to be further verified.

In order to explore temporal-spatial variability of farmland soil pH at Enshi Antonomous Prefecture, Hubei, China, soil pH during the past three decades was analyzed, using the datasets of the Second National Soil Survey (1980-1983) and the Cultivated Land Quality Evaluation (2010-2013). The natural and human factors inducing the change of soil pH were evaluated to provide theoretical guidance for further soil acidification management. Results showed that acidic soil (i.e., pH＜6.5) and neutral and alkaline soil (i.e., pH 6.5-8.5) were accounted for 98.4% and 1.6% in the farmland during the period of 2010-2013, respectively. The ratio increased 61.4% for the acidic soil but decreased 61.2% for the neutral and alkaline soil as compared with the period of 1980-1983. In addition, there was no alkaline soil (pH8.5) in the region in 2010-2013. According to the dataset of the Second National Soil Survey (1980-1983), acidic soil was mainly distributed at Laifeng, Lichuan, Xuanen and Xianfeng counties, with the area ratio of 74.4%, 63.5%, 61.3% and 60.7%, respectively. For the period of 2010-2013, the ratio of acidic soil enhanced widely which was above 96% for each county. At Enshi Autonomous Prefecture, farmland soil showed an obvious acidification trend during the past three decades, with spatial variation of higher in the eastern part and lower in the western part of the region. Furthermore, soil pH decline occurred among different land use types in different areas. Overall, farmland soil pH declined 0.90 on average, with 1.14 decrease for upland and 0.87 for paddy soil, respectively. Clearly, upland soil acidification was severe than paddy soil. Factors related to soil acidification in the Enshi Autonomous Prefecture were mainly human factors such as unreasonable fertilizer combination, fertilizer ratio change, and more base cations taking away by high crop yield.以第二次土壤普查(1980—1983年)和耕地质量评价(2010—2013年)两个不同时期恩施州土壤pH数据为基础,对恩施州耕地土壤pH近30年时空变化进行了研究,明确了恩施州耕地土壤pH值变化特征,并初步探讨了导致土壤pH变化的自然因素和人为因素,以期为制定土壤酸化控制对策提供理论指导.结果表明: 2010—2013年,恩施州pH＜6.5的酸性土壤占耕地面积的98.4%,6.5～8.5中性偏碱性土壤仅占耕地面积的1.6%;与1980—1983年相比,酸性土壤(pH＜6.5)面积比例提高了61.4%,中性偏碱性土壤(pH在6.5～8.5)面积比例减少了61.2%,pH＞8.5的强碱性耕地土壤在全州已基本消失.1980—1983年,pH＜6.5的耕地土壤主要分布在来凤县、利川市、宣恩县和咸丰县,面积比例分别为74.4%、63.5%、61.3%和60.7%,至2010—2013年,恩施州酸性土壤分布更加广泛,各县市酸性土壤(pH＜6.5)面积比例均达到96%以上.近30年来,恩施州土壤呈酸化趋势,土壤pH空间分布呈现东高西低格局.不同区域、不同耕地利用类型土壤pH值均发生不同程度的下降.耕地土壤pH整体下降了0.90,其中,旱地土壤pH下降了1.14,水田土壤pH下降了0.87,旱地土壤酸化程度大于水田.恩施州土壤酸化主要受肥料结构、配比变化及高产作物收获带走大量盐基养分等人为因素影响.

In this paper, three-dimensional integration framework of landslide monitoring data was proposed in the idea of mineral point-source information system and the WebGIS technology based on ActiveX. Seamless integration of data related to landslide monitoring,such as basic geographic data, geological survey data and sensor data was realized. In this process, program algorithm automatically handled method and visual interpretation in three-dimensional environment were used to improve the accuracy of landslide monitoring data. Furthermore，the suitability of landslide monitoring database was improved by separating landslide monitoring data from prediction mathematical model. All this provides the excellent basis for the stability evaluation and forecast of landslide. The monitoringproject of HuangTuPo landslide in Three Gorges Reservoir of China was taken as example to verify feasibility of the method.

This paper by using theories and bibliometrics methods, researches the papers on Building Information Molding (BIM) from growth law of papers, distribution of paper authors, periodicals and keywords for the statistic and analysis with EXCEL, NOTEEXPRESS data analysis and processing tool. The research priorities and hot spots of BIM are summarized.

Return voltage diagnostic method is an effective method of non-destructive diagnosis in transformer insulating state. The current study is that through experiments get polarization spectrum to analysis the transformer insulating state, but not yet carried out the influence of various factors to the experimental results. So, based on the Debye model and specific parameters comes from one equivalent model of the actual transformer, this paper using RVM methods to simulation analysis maximum return voltage and dominant time constant under different factors. Simulation results show that the diagnostic methods that combine maximum return voltage value with dominant time constant can preferably reflect the transformer insulation state.

In recent years, with the development of the smart grid and high-voltage transmission technology, more and more attention has been paid online monitoring of high-voltage capacitive equipment. This paper developed a high-voltage capacitive equipment on-line monitoring system including hardware and software system. Hardware design takes DSP and precision AD as center including signal acquisition and conditioning unit, software part takes modular design including data processing and data query and acquisition control. The system uses zero flux micro-current sensors to collected signals and uses optical fiber to transmission signal, so, the phase measurement error can be control in and signal synchronous transmission can be guarantee. Field application shows that the system data accurate, reliable, stable operation.

Harmonic analysis method for measurement of dielectric loss, due to the impact of fluctuations in grid frequency and higher harmonics, it is difficult to do the synchronous sampling, which reduces the accuracy of the measurements (especially the phase).In order to improve measurement accuracy, this paper presents a new method of calculation based on the energy moment of quasi-periodic interpolation algorithm. First, using a high frequency to sample the original signal, and then using the energy moment balance theory accurately measure the fundamental frequency, further calculating the integral period sampling rate and integral period samples, and last making integral period re-sampling and FFT calculation after interpolation. The simulation results show that this algorithm is high accuracy, good stability, less affected by the frequency fluctuation, harmonic proportion and initial phase.

The meshless finite volume method was employed to enforce the conservation of momentum in a local weak form. A novel hybrid meshless finite volume method (HMFVM) was proposed. The displacement and the stress were interpolated independently with a hybrid scheme in the process. To enforce the compatibility between stress and displacement, a smoothing stress was introduced via finite volume method. In this way, the HMFVM can avoid the appearance of derivatives of shape functions and improve the efficiency over the orthodox meshless finite volume method. Then, the HMFVM was applied to some Elasto-plastic problems, illustrating that it enjoys high precision and efficiency. As a result, the derivatives of shape function are avoid absolutely.

Embryo quality is strongly dependent on the in-vitro culture environment. Conventionally, IVF/intracytoplasmic sperm injection (ICSI) embryos are examined microscopically every morning (from day 1 to day 6) to assess fertilization, cleavage and embryo quality. Consequently, the frequent exposure to non-optimal conditions outside the incubator may adversely affect embryonic viability and quality. Hence, this study investigated whether reduction of observation frequency outside the incubator can enhance blastocyst formation rate. A total of 285 IVF/ICSI cycles were divided into two groups. Embryos in the control group (103 cycles) were assessed out-of-incubator every day after insemination (day 1 to day 6; six times). In the experimental group (182 cycles), embryos were assessed four times, on days 1, 3, 5 and 6. The total blastocyst formation rate, day-5 blastocyst formation rate, proportion of good blastocysts and number of cryopreserved blastocysts per patient were significantly lower for the control group compared with the experimental group (42.5%, 31.4%, 50.7%, 1.72+/-1.55 versus 52.6%, 40.7%, 60.1%, 2.64+/-2.59, respectively, P0.05); although there were no significant differences in the proportions of good embryos on day 3, blastocyst formation rate on day 6, clinical pregnancy rate and implantation rate. Hence, reduction of the observation frequency of embryos outside the incubator can enhance embryo quality and blastocyst formation rate.

Objectives This study sought to evaluate the outcome of fresh and vitrified-warmed cleavage-stage and blastocyst-stage embryo transfers in patients undergoing ART treatment within an ethnic Chinese population. Study design We compared the clinical results of embryo transfer on the 3rd (cleavage stage) or 5th (blastocyst stage) day after oocyte retrieval, including clinical pregnancy rates, implantation rates and multiple pregnancy rates. Results Our data showed that blastocyst transfer on day 5 did not significantly increase clinical pregnancy rate (41.07% vs 47.08%, p>0.05) and implantation rate (31.8% vs 31.2%, p>0.05) in patients under 35 years of age, in comparison with day 3 cleavage stage embryo transfer. In patients older than 35 years of age, the clinical pregnancy rate after blastocyst transfer was slightly decreased compared with cleavage stage embryo transfer (33.33% vs 42.31%, p>0.05). Unexpectedly, It was found that vitrified-warmed blastocyst transfer resulted in significantly higher clinical pregnancy rate (56.8%) and implantation rate (47%) compared with fresh blastocyst transfer in controlled stimulation cycles (41.07% and 31.8%, respectively). For patients under 35 years of age, the cumulative clinical pregnancy rate combining fresh and vitrified-warmed blastocyst transfer cycles were significantly higher compared to just cleavage-stage embryo transfer (70.1% versus 51.8%, p Conclusions In an ethnic Chinese patient population, fresh blastocyst transfer does not significantly increase clinical pregnancy rate. However, subsequent vitrified-warmed blastocyst transfer in a non-controlled ovarian hyperstimulation cycle dramatically improves clinical outcomes. Therefore, blastocyst culture in tandem with vitrified-warmed blastocyst transfer is recommended as a favourable and promising protocol in human ART treatment, particularly for ethnic Chinese patients.

In order to study the spectral line shift property of prism-dispersive imaging spectrometer, the influencing factors and mechanisms of spectral line shift were presented, and the mathematical model based on linear optics model was established to describe the spectral line shift property. Code V API functions was used, in Matlab environment, to verify the validity of mathematical model, and the sensitivity coefficient of spectral line shift was analyzed. Results indicate that rigid body motion of optical mirror surface generated by environmental variation is the key causation of spectral line shift. When the decenter of mirror surface is no more than 0.2 mm and the tilt is less than 0.02 degrees, the value of spectral line shift of different wavelengths at different fields is equivalent, and the error is less than 0.1 pixel. Spectral line shift due to mirror rigid body motion is linear and independent, and the total shift of the spectral line is the algebraic sum of values produced by the single freedom of motion (DOF) of single mirror surface. The mathematical model based on linear optics model can be used to study the spectral line shift property of the prism-dispersive imaging spectrometer. It will provide some guidance for spectral calibration and spectral property analysis under complex work condition.

Hyperspectral imager has more spectral channels and higher spectral resolution compared to normal spectral instrument. Stray light is one of the important reasons affecting the spectral accuracy of the hyperspectral imager, but the current stray light measurements can't meet the need. Definition, sources and harmfulness of stray light are described in the present paper. The feasibility and superiority of the stray light factor d(i,j), used to describe the stray light characteristics of the spectral instruments, is investigated thoroughly, where the definition, physical significance and value of engineering application of stray light interference factor fi(lamda) and stray light disturbance factor Fi(lamda) are given. Finally, the system components, measurement procedure and measurement results of the stray light measurement system, using narrow-band filter, are introduced. Results show that the stray light factor d(i,j) meets the need of the stray light measurement because it can indicate the stray light characteristics of the spectral instruments without relationship to the light source, filter, detector and other measurement conditions, and the measurement efficiency is increased at least one-fold than the spectral stray light factors method.

Vitrification is an effective method for the cryopreservation of mammalian embryos. Nevertheless, it is unclear which embryonic developmental stage is the most suited for vitrification and would ensure maximal developmental competence upon subsequent warming. This study, therefore, compared the effects of cryotop vitrification on the developmental competence of murine morula and blastocyst stage embryos. Additionally, trophectoderm (TE) and inner cell mass (ICM) cell numbers were compared in two hatched blastocyst groups derived from vitrified morulae and blastocysts, respectively. The post-vitrification survival rates for mouse embryos at the morula and blastocyst stage were 95.4% (186/195) and 96.5% (195/202), respectively. The blastocyst formation rate was significantly lower for vitrified morulae (90.3%) compared with the non-vitrified control group (98.4%) (P < 0.05). The hatching rates were similar between the vitrified morula (79.6%) and the vitrified blastocyst (81.0%) groups. When further development to the fully hatched blastocyst stage was compared, fully hatched blastocysts derived from vitrified morulae had significantly higher cell counts for both the ICM and TE lineage, as compared with hatched blastocysts derived from vitrified blastocysts (P < 0.001). Cryotop vitrification of mouse embryos at the morula stage rather than blastocyst stage would thus ensure a higher degree of post-warming developmental competence.