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4 results on '"Juliette Galindo"'

1. Impaired Neurovascular Coupling and Increased Functional Connectivity in the Frontal Cortex Predict Age‐Related Cognitive Dysfunction

Author

Peter Mukli, Camila B. Pinto, Cameron D. Owens, Tamas Csipo, Agnes Lipecz, Zsofia Szarvas, Anna Peterfi, Ana Clara da Costa Pinaffi Langley, Jordan Hoffmeister, Frigyes Samuel Racz, Jonathan W. Perry, Stefano Tarantini, Ádám Nyúl‐Tóth, Farzaneh A. Sorond, Yuan Yang, Judith A. James, Angelia C. Kirkpatrick, Calin I. Prodan, Peter Toth, Juliette Galindo, Andrew W. Gardner, William E. Sonntag, Anna Csiszar, Zoltan Ungvari, and Andriy Yabluchanskiy

Subjects
aging, cognitive decline, functional connectivity, functional near‐infrared spectroscopy, neurovascular coupling, Science
Abstract

Abstract Impaired cerebrovascular function contributes to the genesis of age‐related cognitive decline. In this study, the hypothesis is tested that impairments in neurovascular coupling (NVC) responses and brain network function predict cognitive dysfunction in older adults. Cerebromicrovascular and working memory function of healthy young (n = 21, 33.2±7.0 years) and aged (n = 30, 75.9±6.9 years) participants are assessed. To determine NVC responses and functional connectivity (FC) during a working memory (n‐back) paradigm, oxy‐ and deoxyhemoglobin concentration changes from the frontal cortex using functional near‐infrared spectroscopy are recorded. NVC responses are significantly impaired during the 2‐back task in aged participants, while the frontal networks are characterized by higher local and global connection strength, and dynamic FC (p < 0.05). Both impaired NVC and increased FC correlate with age‐related decline in accuracy during the 2‐back task. These findings suggest that task‐related brain states in older adults require stronger functional connections to compensate for the attenuated NVC responses associated with working memory load.

Published
2024
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2. Cerebral small vessel disease pathology in COVID-19 patients: A systematic review

Author

Cameron D. Owens, Camila Bonin Pinto, Sam Detwiler, Peter Mukli, Anna Peterfi, Zsofia Szarvas, Jordan R. Hoffmeister, Juliette Galindo, Jila Noori, Angelia C. Kirkpatrick, Tarun W. Dasari, Judith James, Stefano Tarantini, Anna Csiszar, Zoltan Ungvari, Calin I. Prodan, and Andriy Yabluchanskiy

Subjects
Aging, Neurology, Molecular Biology, Biochemistry, Biotechnology
Published
2023
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3. The effect of perceptual reasoning abilities on confrontation naming performance: An examination of three naming tests

Author

Janice C. Marceaux, Jason R. Soble, Juliette Galindo, Justin J.F. O’Rourke, Karin J.M. McCoy, David Andrés González, Jonathan M. Highsmith, Jeffrey A. Sordahl, and Edan A. Critchfield

Subjects
Adult, Male, 050103 clinical psychology, Concept Formation, Neuropsychological Tests, Thinking, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Concept learning, medicine, Humans, Names, 0501 psychology and cognitive sciences, Neuropsychological assessment, Aged, Language, Aged, 80 and over, Intelligence Tests, Analysis of Variance, Intelligence quotient, medicine.diagnostic_test, 05 social sciences, Neuropsychology, Wechsler Adult Intelligence Scale, Cognition, Middle Aged, Test (assessment), Clinical Psychology, Boston Naming Test, Neurology, Regression Analysis, Female, Neurology (clinical), Psychology, Photic Stimulation, 030217 neurology & neurosurgery, Cognitive psychology
Abstract

Confrontation naming tests are a common neuropsychological method of assessing language and a critical diagnostic tool in identifying certain neurodegenerative diseases; however, there is limited literature examining the visual-perceptual demands of these tasks. This study investigated the effect of perceptual reasoning abilities on three confrontation naming tests, the Boston Naming Test (BNT), Neuropsychological Assessment Battery (NAB) Naming Test, and Visual Naming Test (VNT) to elucidate the diverse cognitive functions underlying these tasks to assist with test selection procedures and increase diagnostic accuracy.A mixed clinical sample of 121 veterans were administered the BNT, NAB, VNT, and Wechsler Adult Intelligence Scale-4th Edition (WAIS-IV) Verbal Comprehension Index (VCI) and Perceptual Reasoning Index (PRI) as part of a comprehensive neuropsychological evaluation.Multiple regression indicated that PRI accounted for 23%, 13%, and 15% of the variance in BNT, VNT, and NAB scores, respectively, but dropped out as a significant predictor once VCI was added. Follow-up bootstrap mediation analyses revealed that PRI had a significant indirect effect on naming performance after controlling education, primary language, and severity of cognitive impairment, as well as the mediating effect of general verbal abilities for the BNT (B = 0.13; 95% confidence interval, CI [.07, .20]), VNT (B = 0.01; 95% CI [.002, .03]), and NAB (B = 0.03; 95% CI [.01, .06]).Findings revealed a complex relationship between perceptual reasoning abilities and confrontation naming that is mediated by general verbal abilities. However, when verbal abilities were statistically controlled, perceptual reasoning abilities were found to have a significant indirect effect on performance across all three confrontation naming measures with the largest effect noted with the BNT relative to the VNT and NAB Naming Test.

Published
2015
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4. A review of the use and psychometric properties of the Cognitive Log (Cog-Log) amongst adults with acquired brain injury

Author

Lucas D. Driskell, Juliette Galindo, and Stephanie Lenox

Subjects
medicine.medical_specialty, Rehabilitation, Psychometrics, business.industry, medicine.medical_treatment, fungi, Reproducibility of Results, Physical Therapy, Sports Therapy and Rehabilitation, Cognition, PsycINFO, medicine.disease, Psychiatry and Mental health, Clinical Psychology, Cog, Physical medicine and rehabilitation, Brain Injuries, mental disorders, Humans, Medicine, Cognition Disorders, business, human activities, Acquired brain injury
Abstract

This Rehabilitation Measures Database summary provides a review of the psychometric properties of the Cog-Log in individuals with acquired brain injury. A full review of the Cog-Log as well as reviews of over 400 other instruments for patients with various health conditions can be found at www.sralab.org/rehabilitation-measures. (PsycINFO Database Record

Published
2018
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