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Your search keyword '"Judicone, Coralie"' showing total 18 results
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18 results on '"Judicone, Coralie"'

1. Comparison of assays measuring extracellular vesicle tissue factor in plasma samples: communication from the ISTH SSC Subcommittee on Vascular Biology

Author

Bonifay, Amandine, Mackman, Nigel, Hisada, Yohei, Sachetto, Ana Teresa Azevedo, Hau, Chi, Gray, Elaine, Hogwood, John, Aharon, Anat, Badimon, Lina, Barile, Lucio, Baudar, Justine, Beckmann, Lennart, Benedikter, Birke, Bolis, Sara, Bouriche, Tarik, Brambilla, Marta, Burrello, Jacopo, Camera, Marina, Campello, Elena, Ettelaie, Camille, Faille, Dorothée, Featherby, Sophie, Franco, Corentin, Guldenpfennig, Maite, Hansen, John-Bjarne, Judicone, Coralie, Kim, Yohan, Kristensen, Soren Risom, Laakmann, Katrin, Langer, Florian, Latysheva, Nadezhda, Lucien, Fabrice, de Menezes, Erika Marques, Mullier, François, Norris, Philip, Nybo, Jette, Orbe, Josune, Osterud, Bjarne, Paramo, Jose A., Radu, Claudia M., Roncal, Carmen, Samadi, Nazanin, Snir, Omri, Suades, Rosa, Wahlund, Casper, Chareyre, Corinne, Abdili, Evelyne, Martinod, Kimberly, Thaler, Johannes, Dignat-George, Françoise, Nieuwland, Rienk, and Lacroix, Romaric

Published
2024
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6. Circulating microvesicles correlate with radiation proctitis complication after radiotherapy

Author

Ribault, Alexandre, Benadjaoud, Mohamed Amine, Squiban, Claire, Arnaud, Laurent, Judicone, Coralie, Leroyer, Aurélie, Rousseau, Alexandra, Huet, Christelle, Guha, Chandan, Benderitter, Marc, Lacroix, Romaric, Flamant, Stephane, Chen, Emily, Simon, Jean-Marc, Tamarat, Radia, Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Hôpital de la Timone [CHU - APHM] (TIMONE), Centre recherche en CardioVasculaire et Nutrition = Center for CardioVascular and Nutrition research (C2VN), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité de Recherche Clinique de l’Est Parisien [CHU Saint-Antoine] (URC-EST), Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO)-CHU Tenon [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Trousseau [APHP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Rothschild [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-CHU Saint-Antoine [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Direction de la Recherche Clinique et de l'Innovation [AP-HP] (DRCI), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP), Albert Einstein College of Medicine [New York], Columbia University Medical Center (CUMC), Columbia University [New York], Service d'Oncologie Radiothérapie [CHU Pitié Salpétrière], CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU), Sorbonne Université (SU), INCa through PHRC AOM08324. EIC was supported by the National Institutes of Health (5P30CA013696-42, NIH/NCI and 2U19AI067773-11, NIH/NIAID), Cosenza, Bruno, Laboratoire de Radiobiologie des expositions médicales (IRSN/PSE-SANTE/SERAMED/LRMed), Service de recherche en radiobiologie et en médecine régénérative (IRSN/PSE-SANTE/SERAMED), Institut de Radioprotection et de Sûreté Nucléaire (IRSN)-Institut de Radioprotection et de Sûreté Nucléaire (IRSN), Centre d'investigation clinique Paris Est [CHU Pitié Salpêtrière] (CIC Paris-Est), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-CHU Pitié-Salpêtrière [AP-HP], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)-Sorbonne Université (SU), Laboratoire de dosimétrie des rayonnements ionisants (IRSN/PSE-SANTE/SDOS/LDRI), Service de dosimétrie (IRSN/PSE-SANTE/SDOS), Pôle Santé Environnement - Direction Santé (IRSN/PSE-SANTE), Laboratoire de Radiobiologie des expositions accidentelles (IRSN/PSE-SANTE/SERAMED/LRAcc), and Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Sorbonne Université (SU)

Subjects
[SDV] Life Sciences [q-bio], Multidisciplinary, [SDV]Life Sciences [q-bio]
Abstract

In a large retrospective study, we assessed the putative use of circulating microvesicles (MVs), as innovative biomarkers of radiation toxicity in a cohort of 208 patients with prostate adenocarcinoma overexposed to radiation. The level of platelet (P)-, monocyte (M)- and endothelial (E)-derived MVs were assessed by flow cytometry. Rectal bleeding toxicity scores were collected at the time of blood sampling and during the routine follow-up and were tested for association with MVs using a multivariate logistic regression. MVs dosimetric correlation was investigated using dose volume histograms information available for a subset of 36 patients. The number of PMVs was significantly increased in patients with highest toxicity grades compared to lower grades. Risk prediction analysis revealed that increased numbers of PMVs, and an increased amount of MMVs relative to EMVs, were associated with worst rectal bleeding grade compared to the time of blood sampling. Moreover, a significant correlation was found between PMV and MMV numbers, with the range of doses up to the median exposure (40 Gy) of bladder/rectum and anterior rectal wall, respectively. MVs could be considered as new biomarkers to improve the identification of patients with high toxicity grade and may be instrumental for the prognosis of radiation therapy complications.

Published
2022
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8. Circulating microvesicles correlate with radiation proctitis complication after radiotherapy

Author

Ribault, Alexandre, primary, Benadjaoud, Mohamed Amine, additional, Squiban, Claire, additional, Arnaud, Laurent, additional, Judicone, Coralie, additional, Leroyer, Aurélie S., additional, Rousseau, Alexandra, additional, Huet, Christelle, additional, Guha, Chandan, additional, Benderitter, Marc, additional, Lacroix, Romaric, additional, FLAMANT, Stephane, additional, Chen, Emily I., additional, Simon, Jean-Marc, additional, and Tamarat, Radia, additional

Published
2022
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11. A new assay to evaluate microvesicle plasmin generation capacity: validation in disease with fibrinolysis imbalance

Author

Cointe, Sylvie, primary, Harti Souab, Karim, additional, Bouriche, Tarik, additional, Vallier, Loris, additional, Bonifay, Amandine, additional, Judicone, Coralie, additional, Robert, Stéphane, additional, Armand, Romain, additional, Poncelet, Philippe, additional, Albanese, Jacques, additional, Dignat‐George, Françoise, additional, and Lacroix, Romaric, additional

Published
2018
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12. Standardization of pre-analytical variables in plasma microparticle determination: results of the International Society on Thrombosis and Haemostasis SSC Collaborative workshop

Author

Lacroix, Romaric, Judicone, Coralie, Mooberry, Micah, Boucekine, Mohamed, Key, Nigel S, Dignat-George, Françoise, The ISTH SSC Workshop, Bailly, Nicolas, Mullier, François, UCL - SSS/IREC/MONT - Pôle Mont Godinne, and UCL - (MGD) Service d'hématologie

Subjects
business.industry, Cancer, Inflammation, Hematology, Phosphatidylserine, medicine.disease, Bioinformatics, Thrombosis, chemistry.chemical_compound, chemistry, Coagulation, Antigen, Apoptosis, medicine, Cancer research, medicine.symptom, business, Cell activation
Abstract

Microparticles (MP) are sub-micron sized vesicles released by activated or apoptotic cells. They are generally defined as 0.1 to 1 μm membrane particles that expose the anionic phospholipid phosphatidylserine (PS) and membrane antigens representative of their cellular origin [1]. It is now well recognized that MP behave as vectors of bioactive molecules, playing a role in blood coagulation, inflammation, cell activation and cancer metastasis. In clinical practice, circulating MP originating from blood and vascular cells are elevated in a variety of prothrombotic and inflammatory disorders, cardiovascular diseases, autoimmune conditions, infectious diseases and cancer [1-3]. © 2013 International Society on Thrombosis and Haemostasis.

Published
2013
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13. Microparticles and Fibrinolysis

Author

Vallier, Loris, primary, Cointe, Sylvie, primary, Lacroix, Romaric, primary, Bonifay, Amandine, primary, Judicone, Coralie, primary, Dignat-George, Françoise, primary, and Kwaan, Hau, additional

Published
2016
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14. Cytology-based treatment decision in primary lung cancer: Is it accurate enough?

Author

Roll, Patrice, Roca, Elisa, Lacroix, Romaric, Judicone, Coralie, Laroumagne, Sophie, Robert, Stéphane, Cointe, Sylvie, Muller, Alexandre, Kaspi, Elise, Brisson, Alain, Tantucci, Claudio, Astoul, Philippe, Dignat-George, Françoise, Barthélémy, Florian, Navarro, Claire, Fayek, Racha, Da Silva, Nathalie, Sigaudy, Sabine, Oshima, Junko, Bonne, Gisèle, Papadopoulou-Legbelou, Kyriaki, Evangeliou, Athanasios, Spilioti, Martha, LeMerrer, Martine, Wevers, Ron, Morava, Eva, Robaglia-Schlupp, Andrée, Lévy, Nicolas, Bartoli, Marc, De Sandre-Giovannoli, Annachiara, Hadj-Rabia, Smail, Mashiah, Jacob, Boyer, Amandine, Bourgeois, Patrice, Van Kien, Philippe Khau, Bodemer, Christine, Navarro, Claire Laure, Esteves-Vieira, Vera, Courrier, Sébastien, Duong Nguyen, Thuy, Huong, Le Thi Thanh, Meinke, Peter, Schröder, Winnie, Cormier-Daire, Valérie, Sznajer, Yves, Amor, David, Lagerstedt, Kristina, Biervliet, Martine, van den Akker, Peter, Cau, Pierre, BADENS, Catherine, Wehnert, Manfred, Sakr, Lama, Payan, Marie-José, Liprandi, Agnès, Dutau, Hervé, Loundou, Anderson, Barlesi, Fabrice, Aix Marseille Université (AMU), Assistance Publique - Hôpitaux de Marseille (APHM), Laboratoire de Biologie Cellulaire [Hôpital de la Timone - APHM], Assistance Publique - Hôpitaux de Marseille (APHM)- Hôpital de la Timone [CHU - APHM] (TIMONE), Marseille medical genetics - Centre de génétique médicale de Marseille (MMG), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM), and Institut National de la Santé et de la Recherche Médicale (INSERM)-Aix Marseille Université (AMU)

Subjects
Adult, Male, Pulmonary and Respiratory Medicine, Cancer Research, medicine.medical_specialty, Pathology, Lung Neoplasms, Cytodiagnosis, [SDV]Life Sciences [q-bio], Cytological Techniques, Adenocarcinoma of Lung, Adenocarcinoma, Malignancy, 03 medical and health sciences, 0302 clinical medicine, Bronchoscopy, Carcinoma, Non-Small-Cell Lung, Biopsy, medicine, Carcinoma, Humans, Neoplasms, Squamous Cell, Lung cancer, ComputingMilieux_MISCELLANEOUS, Aged, Retrospective Studies, 030304 developmental biology, Aged, 80 and over, 0303 health sciences, medicine.diagnostic_test, business.industry, Biopsy, Needle, Not Otherwise Specified, Middle Aged, medicine.disease, Small Cell Lung Carcinoma, respiratory tract diseases, 3. Good health, Oncology, 030220 oncology & carcinogenesis, Female, Radiology, business
Abstract

Accurate distinction of lung cancer types has become increasingly important as recent trials have shown differential response to chemotherapy among non-small cell lung carcinoma (NSCLC) subtypes. Cytological procedures are frequently used but their diagnostic accuracy has been previously questioned. However, new endoscopic and cytological techniques might have improved cytological accuracy in comparison with prior findings. The aim of this study was to reassess cytological accuracy for diagnosis of lung cancer subtypes. A retrospective chart review of subjects who underwent fiberoptic bronchoscopy (FOB) for suspicion of lung cancer in 2007–2008, was undertaken. Reports of bronchoscopically derived cytological specimens were compared to those of histological material. Endoscopic findings and specific investigational techniques were taken into account. A total of 467 FOB with both cytological and histological diagnostic techniques were performed in 449 subjects. Patients consisted of 345 men and 104 women (median age, 65 yrs). Cytology proved malignancy in 157 patients. Cytologically diagnosed carcinomas were classified into squamous cell carcinoma (SqCC) in 56, adenocarcinoma (ADC) in 6, small cell lung carcinoma (SCLC) in 12, non-small cell lung carcinoma not otherwise specified (NSCLC-NOS) in 71, and unclassified carcinoma in 12. Cytology correlated fairly with biopsy specimens, as agreement was observed in 83% of SCLC, 100% of ADC, 74% of SqCC and 8% of NSCLC-NOS. Interestingly, 61% of cytologically identified NSCLC-NOS were classified as ADC by histology. Cytological accuracy improved in case of an endobronchial lesion, mainly for SqCC. These results indicate that cytological accuracy remains fair with regard to diagnosis of squamous and non-squamous lung cancer subtypes. Improvement of cytological accuracy is expected however with novel diagnostic strategies.

Published
2012
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15. Detection of EpCAM-positive microparticles in pleural fluid: A new approach to mini-invasively identify patients with malignant pleural effusions

Author

Roca, Elisa, primary, Lacroix, Romaric, additional, Judicone, Coralie, additional, Laroumagne, Sophie, additional, Robert, Stéphane, additional, Cointe, Sylvie, additional, Muller, Alexandre, additional, Kaspi, Elise, additional, Roll, Patrice, additional, Brisson, Alain R., additional, Tantucci, Claudio, additional, Astoul, Philippe, additional, and Dignat-George, Françoise, additional

Published
2015
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16. Detection of EpCAM-positive microparticles in pleural fluid: A new approach for the diagnosis of the tumoral origin of pleural effusions

Author

Roca, Elisa, primary, Lacroix, Romaric, additional, Judicone, Coralie, additional, Laroumagne, Sophie, additional, Robert, Stephane, additional, Cointe, Sylvie, additional, Muller, Alexandre, additional, Kaspi, Elise, additional, Roll, Patrice, additional, Brisson, Alain, additional, Tantucci, Claudio, additional, Astoul, Philippe, additional, and Dignat-George, Françoise, additional

Published
2015
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18. Detection of EpCAM-positive microparticles in pleural fluid: A new approach to mini-invasively identify patients with malignant pleural effusions.

Author

Roca E, Lacroix R, Judicone C, Laroumagne S, Robert S, Cointe S, Muller A, Kaspi E, Roll P, Brisson AR, Tantucci C, Astoul P, and Dignat-George F

Subjects
Cell-Derived Microparticles pathology, Cryoelectron Microscopy, Enzyme-Linked Immunosorbent Assay, Female, Flow Cytometry, Humans, Male, Microscopy, Electron, Transmission, Pleural Effusion, Malignant metabolism, Prospective Studies, Biomarkers, Tumor metabolism, Cell-Derived Microparticles ultrastructure, Epithelial Cell Adhesion Molecule metabolism, Neoplasms physiopathology, Pleural Effusion, Malignant diagnosis
Abstract

Pleural biomarkers allowing to mini-invasively discriminate benign from malignant pleural effusions are needed. Among potential candidates, microparticles (MPs) are extracellular vesicles that vectorize antigen derived from the parent cell. We hypothesized that tumor-derived MPs could be present in the pleural liquid and help to identify patients with malignant pleural effusions. Using highly sensitive flow cytometry and cryo-electron microscopy, we showed that large amounts of MPs from hematopoïetic and vascular origin could be detectable in pleural fluids. Their level did not differ between benign (n = 14) and malignant (n = 71) pleural effusions. Analysis of selected tumoral associated antigens (podoplanin, mucin 1 and EpCAM, epithelial-cell-adhesion-molecule) evidenced for the first time the presence of tumor-derived MPs expressing EpCAM in malignant pleural fluids only (Specificity = 93%, Sensitivity = 49% and 45% for flow cytometry and ELISA, respectively). The detection of EpCAM-positive-MPs (EpCAM + MPs) by flow cytometry showed a better specificity and sensitivity than ELISA to distinguish between pleural carcinoma and the others malignant pleural effusions (MPE; Sp: 96% vs 89%; Se: 79% vs 66%). Combining EpCAM+ MPs and cytology improved the diagnosis of MPE compared to cytology alone. This study establishes the basis for using EpCAM+ MPs as a promising new biomarker that could be added to the armamentarium to mini-invasively identify patients with malignant pleural effusions.

Published
2016
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