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1. Alleviation of OVA-Induced Airway Inflammation by Flowers of Inula japonica in a Murine Model of Asthma.

Author

Young Na Park, Youn Ju Lee, Jeon Hyeun Choi, Meihua Jin, Ju Rae Yang, Ying Li, Jiean Lee, Xian Li, Keuk-Jun Kim, Jong Keun Son, Hyeun Wook Chang, Jong Yeon Kim, and Eunkyung Lee

Subjects
THERAPEUTIC use of plant extracts, ANTIASTHMATIC agents, EOSINOPHILS, TH2 cells, CYTOKINES, BRONCHOALVEOLAR lavage, METHACHOLINE compounds
Abstract

The article examines the anti-asthmatic effects of the flowers of Inulae Flos (Inula japonica) extract (IFE) on ovalbumin (OVA)-induced asthma and airway hyper-responsiveness (AHR). It explores the efficacy of the IFE treatment in reducing the eosinophils and Th2 cytokines percentage in the bronchoalveolar lavage fluid (BALF). It suggests that the IFE suppressed AHR induced by aerosolized methacholine in OVA-induced asthma and inhibited inflammatory cell infiltration and mucus hypersecretion.

Published
2011
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