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183 results on '"Ju, Jung-Won"'

3. Molecular Identification of Spotted Fever Group Rickettsiae in Ticks in the Republic of Korea.

Author

Seo, Ji-Ye, Park, Jin-Seo, Lee, Hee-Il, and Ju, Jung-Won

Subjects
POLYMERASE chain reaction, RICKETTSIAL diseases, AMBLYOMMA, IXODES, TICKS, TICK infestations
Abstract

The Rickettsia species transmitted by ticks are mostly classified within the spotted fever group rickettsiae (SFGR), which causes tick-borne rickettsiosis. Although efforts have been made to investigate their prevalence in the Republic of Korea (ROK), research has been limited to certain areas. Furthermore, the pooling method for ticks does not fully reflect the exact infection rate. Therefore, we aimed to perform molecular identification of SFGR in ticks to elucidate the current prevalence of tick-borne rickettsiosis in the ROK. The SFGR of ticks was identified using polymerase chain reaction targeting the 17 kDa antigen, ompA, and gltA, followed by sequencing for species identification and phylogenetic analysis. In total, 302 ticks belonging to four species (Haemaphysalis flava, H. longicornis, Ixodes nipponensis, and Amblyomma testudinarium) were collected between April and November 2022. The overall SFGR infection rate was 26.8% (81/302 patients). Both adult and nymphal ticks and the SFGR infection rate increased during April–May, reaching their peaks in June, followed by a marked decline in August and July, respectively. Phylogenetic analysis revealed three species (R. monacensis, R. heilongjiangensis, and Candidatus R. jingxinensis) of SFGR. Thus, our results emphasize the importance of tick surveys for the prevention and management of tick-borne rickettsiosis. [ABSTRACT FROM AUTHOR]

Published
2024
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21. Prevalence of Clonorchis sinensis Infection among Residents along 5 Major Rivers in the Republic of Korea

Author

Jeong, Young-Il, Shin, Hee-Eun, Lee, Sang-Eun, Cheun, Hyeng-Il, Ju, Jung-Won, Kim, Jung-Yeon, Park, Mi Yeoun, and Cho, Shin-Hyeong

Subjects
Adult, Male, Adolescent, prevalence, Brief Communication, 5 major rivers, Feces, Young Adult, Rivers, Raw Foods, Republic of Korea, Animals, Humans, Child, Parasite Egg Count, Aged, Aged, 80 and over, Clonorchis sinensis, Korea, riverside resident, Infant, Feeding Behavior, Middle Aged, clonorchiasis, Child, Preschool, Female
Abstract

Clonorchis sinensis is currently the most important parasite affecting public health problems in the Republic of Korea. We investigated the prevalence of C. sinensis infection among residents living along 5 major rivers in Korea. A total of 42,562 individual stool samples were collected from 37 localities and examined using the formalin-ether sedimentation technique. Helminth eggs were detected in 4,052 (9.5%) residents and 3,586 (8.4%) were infected with C. sinensis. The egg positive rate of C. sinensis in Nakdong, Seomjin, Geum, Yeongsan, and Han River was 11.7%, 9.9%, 6.5%, 3.1%, and 1.0%, respectively. The overall prevalence of clonorchiasis by sex was 11.2% in males and 6.2% in females. The age-prevalence was the highest in the 50-59 years band. It has been reconfirmed that the endemicity of clonorchiasis is higher in southern areas of Korea, especially along Nakdong and Seomjin Rivers. A combination of continuous control programs with health education initiatives is urgently required in these highly endemic areas of clonorchiasis in Korea.

Published
2016

22. SpiroESTdb: a transcriptome database and online tool for sparganum expressed sequences tags

Author

Kim Dae-Won, Kim Dong-Wook, Yoo Won Gi, Nam Seong-Hyeuk, Lee Myoung-Ro, Yang Hye-Won, Park Junhyung, Lee Kyooyeol, Lee Sanghyun, Cho Shin-Hyeong, Lee Won-Ja, Park Hong-Seog, and Ju Jung-Won

Subjects
Sparganum, Plerocercoid, Spirometra erinacei, Expressed sequence tags (ESTs), Database, Medicine, Biology (General), QH301-705.5, Science (General), Q1-390
Abstract

Abstract Background Sparganum (plerocercoid of Spirometra erinacei) is a parasite that possesses the remarkable ability to survive by successfully modifying its physiology and morphology to suit various hosts and can be found in various tissues, even the nervous system. However, surprisingly little is known about the molecular function of genes that are expressed during the course of the parasite life cycle. To begin to decipher the molecular processes underlying gene function, we constructed a database of expressed sequence tags (ESTs) generated from sparganum. Findings SpiroESTdb is a web-based information resource that is built upon the annotation and curation of 5,655 ESTs data. SpiroESTdb provides an integrated platform for expressed sequence data, expression dynamics, functional genes, genetic markers including single nucleotide polymorphisms and tandem repeats, gene ontology and KEGG pathway information. Moreover, SpiroESTdb supports easy access to gene pages, such as (i) curation and query forms, (ii) in silico expression profiling and (iii) BLAST search tools. Comprehensive descriptions of the sparganum content of all sequenced data are available, including summary reports. The contents of SpiroESTdb can be viewed and downloaded from the web (http://pathod.cdc.go.kr/spiroestdb). Conclusions This integrative web-based database of sequence data, functional annotations and expression profiling data will serve as a useful tool to help understand and expand the characterization of parasitic infections. It can also be used to identify potential industrial drug targets and vaccine candidate genes.

Published
2012
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