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1. Level of Unique T-Cell Clonotypes Are Associated with Clonal Hematopoiesis and Survival in Patients with Lymphoma Intended for Autologous Stem Cell Transplant

Author

Husby, Simon, primary, Jørgensen, Gustav Ørting, additional, Favero, Francesco, additional, Jespersen, Jakob Schmidt, additional, Gonzalez, German G.R., additional, Nielsen, Christian, additional, Sørensen, Betina, additional, Ebbesen, Lene Hyldahl, additional, Bæch, John, additional, Hastrup, Eva Kannik, additional, Josefsson, Pär L., additional, Thorsgaard, Michael, additional, El-Galaly, Tarec Christoffer, additional, Brown, Peter de Nully, additional, Larsen, Thomas Stauffer, additional, Weisenfeldt, Joachim, additional, and Grønbæk, Kirsten, additional

Published
2021
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2. Mental Health Among Patients with Non-Hodgkin Lymphoma: A Danish Nationwide Study of Psychotropic Drug Use in 7,201 Patients and 36,005 Matched Comparators

Author

Øvlisen, Andreas Kiesbye, primary, Jakobsen, Lasse H., additional, Kragholm, Kristian Hay, additional, Nielsen, René Ernst, additional, Brown, Peter De Nully, additional, Dahl-Soerensen, Rasmus Bo, additional, Frederiksen, Henrik, additional, Mannering, Nikolaj, additional, Josefsson, Pär L., additional, Al-Mashhadi, Ahmed, additional, Jørgensen, Judit M., additional, Dessau-Arp, Andriette, additional, Clausen, Michael Roost, additional, Pedersen, Robert Schou, additional, Torp-Pedersen, Christian, additional, Severinsen, Marianne Tang, additional, and El-Galaly, Tarec Christoffer, additional

Published
2021
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3. CLINICAL IMPACT OF T‐CELL RECEPTOR REPERTOIRE DIVERSITY IN PATIENTS WITH LYMPHOMA UNDERGOING AUTOLOGOUS STEM CELL TRANSPLANTATION

Author

Jørgensen, G. Ø, primary, Favero, F, additional, Schmidt Jespersen, J, additional, Tulstrup, M. R, additional, Rodriguez‐Gonzalez, F. G, additional, Nielsen, A. F, additional, Sørensen, B, additional, Ebbesen, L. H, additional, Bæch, J, additional, Haastrup, E. K, additional, Nielsen, C, additional, Josefsson, Pär L, additional, Thorsgaard, M, additional, El‐Galaly, T. C, additional, Brown, P, additional, Weischenfeldt, J. L, additional, Larsen, T. S, additional, Grønbæk, K, additional, and Husby, S, additional

Published
2021
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4. Minimal relapse risk and early normalization of survival for patients with Burkitt lymphoma treated with intensive immunochemotherapy : an international study of 264 real-world patients

Author

Jakobsen, Lasse H., Ellin, Fredrik, Smeland, Knut B., Wästerlid, Tove, Christensen, Jacob H., Jorgensen, Judit M., Josefsson, Pär L., Ovlisen, Andreas K., Holte, Harald, Blaker, Yngvild N., Grauslund, Jacob H., Bjorn, Jon, Molin, Daniel, Lagerlöf, Ingemar, Smedby, Karin E., Colvin, Katherine, Thanarajasingam, Gita, Maurer, Matthew J., Habermann, Thomas M., Song, Kevin W., Zhu, Katie Y., Gerrie, Alina S., Cheah, Chan Y., El-Galaly, Tarec C., Jakobsen, Lasse H., Ellin, Fredrik, Smeland, Knut B., Wästerlid, Tove, Christensen, Jacob H., Jorgensen, Judit M., Josefsson, Pär L., Ovlisen, Andreas K., Holte, Harald, Blaker, Yngvild N., Grauslund, Jacob H., Bjorn, Jon, Molin, Daniel, Lagerlöf, Ingemar, Smedby, Karin E., Colvin, Katherine, Thanarajasingam, Gita, Maurer, Matthew J., Habermann, Thomas M., Song, Kevin W., Zhu, Katie Y., Gerrie, Alina S., Cheah, Chan Y., and El-Galaly, Tarec C.

Abstract

Non-endemic Burkitt lymphoma (BL) is a rare germinal centre B-cell-derived malignancy with the genetic hallmark of MYC gene translocation and with rapid tumour growth as a distinct clinical feature. To investigate treatment outcomes, loss of lifetime and relapse risk in adult BL patients treated with intensive immunochemotherapy, retrospective clinic-based and population-based lymphoma registries from six countries were used to identify 264 real-world patients. The median age was 47 years and the majority had advanced-stage disease and elevated LDH. Treatment protocols were R-CODOX-M/IVAC (47%), R-hyper-CVAD (16%), DA-EPOCH-R (11%), R-BFM/GMALL (25%) and other (2%) leading to an overall response rate of 89%. The two-year overall survival and event-free survival were 84% and 80% respectively. For patients in complete remission/unconfirmed, the two-year relapse risk was 6% but diminished to 0 center dot 6% for patients reaching 12 months of post-remission event-free survival (pEFS12). The loss of lifetime for pEFS12 patients was 0 center dot 4 (95% CI: -0 center dot 7 to 2) months. In conclusion, real-world outcomes of adult BL are excellent following intensive immunochemotherapy. For pEFS12 patients, the relapse risk was low and life expectancy similar to that of a general population, which is important information for developing meaningful follow-up strategies with increased focus on survivorship and less focus on routine disease surveillance.

Published
2020
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5. Prognostic significance of infectious episodes occurring during first‐line therapy for diffuse large B‐cell lymphoma ‐ A nationwide cohort study

Author

Clausen, Michael R., primary, Ulrichsen, Sinna P., additional, Juul, Maja B., additional, Poulsen, Christian B., additional, Iversen, Brian, additional, Pedersen, Per T., additional, Madsen, Jakob, additional, Pedersen, Robert S., additional, Josefsson, Pär L., additional, Gørløv, Jette S., additional, Nørgaard, Mette, additional, and d'Amore, Francesco, additional

Published
2020
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6. Minimal relapse risk and early normalization of survival for patients with Burkitt lymphoma treated with intensive immunochemotherapy: an international study of 264 real‐world patients

Author

Jakobsen, Lasse H., primary, Ellin, Fredrik, additional, Smeland, Knut B., additional, Wästerlid, Tove, additional, Christensen, Jacob H., additional, Jørgensen, Judit M., additional, Josefsson, Pär L., additional, Øvlisen, Andreas K., additional, Holte, Harald, additional, Blaker, Yngvild N., additional, Grauslund, Jacob H., additional, Bjørn, Jon, additional, Molin, Daniel, additional, Lagerlöf, Ingemar, additional, Smedby, Karin E., additional, Colvin, Katherine, additional, Thanarajasingam, Gita, additional, Maurer, Matthew J., additional, Habermann, Thomas M., additional, Song, Kevin W., additional, Zhu, Katie Y., additional, Gerrie, Alina S., additional, Cheah, Chan Y., additional, and El‐Galaly, Tarec C., additional

Published
2020
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7. Inferior Outcomes for Older Patients in the Adolescent and Young Adult (AYA) Population with Burkitt Lymphoma Treated with Intensive Immunochemotherapy: An International Study of 108 Patients

Author

Ellin, Fredrik, primary, Smeland, Knut B., additional, Wästerlid, Tove, additional, Christensen, Jacob H., additional, Jørgensen, Judit, additional, Josefsson, Pär L., additional, Holte, Harald, additional, Blaker, Yngvild Nuvin, additional, Grauslund, Jacob H., additional, Bjoern, Jon, additional, Molin, Daniel, additional, Lagerlöf, Ingemar, additional, Ekstroem Smedby, Karin Ekstrom, additional, Colvin, Katherine, additional, Thanarajasingam, Gita, additional, Maurer, Matthew J, additional, Habermann, Thomas M., additional, Song, Kevin, additional, Zhu, Katie Yuan, additional, Gerrie, Alina S, additional, Cheah, Chan Y., additional, El-Galaly, Tarec Christoffer C., additional, and Jakobsen, Lasse H., additional

Published
2019
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8. Normalization of Survival and No Relapses after One Year in Adult Burkitt Lymphoma Patients Treated with Intensive Immunochemotherapy: An International Study of 159 Real-World Patients

Author

Jakobsen, Lasse H., primary, Ellin, Fredrik, additional, Smeland, Knut B., additional, Wästerlid, Tove, additional, Christensen, Jacob H., additional, Jørgensen, Judit, additional, Josefsson, Pär L., additional, Holte, Harald, additional, Blaker, Yngvild N., additional, Grauslund, Jacob H., additional, Bjørn, Jon, additional, Molin, Daniel, additional, Lagerlöf, Ingemar, additional, Ekstroem Smedby, Karin, additional, Colvin, Katherine, additional, Thanarajasingam, Gita, additional, Gerrie, Alina S., additional, Cheah, Chan Y., additional, and El-Galaly, Tarec C., additional

Published
2018
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9. Clinical Impact of Clonal Hematopoiesis after Autologous Stem Cell Transplantation for Lymphoma: A National Population-Based Cohort Study

Author

Husby, Simon, primary, Francesco, Favero, additional, Nielsen, Christian, additional, Sørensen, Betina, additional, Bæch, John, additional, Hansen, Jakob Werner, additional, Gonzalez, German G.R., additional, Arboe, Bente, additional, Andersen, Lisbeth Pernille, additional, Hastrup, Eva Kannik, additional, Fischer-Nielsen, Anne, additional, Sækmose, Susanne G, additional, Hansen, Per Boye, additional, Christiansen, Ilse, additional, Clasen-Linde, Erik, additional, Knudsen, Lene Meldgaard, additional, Grell, Kathrine, additional, Segel, Erik Kay, additional, Ebbesen, Lene Hyldahl, additional, Thorsgaard, Michael, additional, Josefsson, Pär L., additional, El-Galaly, Tarec Christoffer, additional, Brown, Peter De Nully, additional, Weisenfeldt, Joachim, additional, Larsen, Thomas Stauffer, additional, and Grønbæk, Kirsten, additional

Published
2018
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10. Final Analysis of the Front-Line Phase III Randomized ACT-1 Trial in Younger Patients with Systemic Peripheral T-Cell Lymphoma Treated with CHOP Chemotherapy with or without Alemtuzumab and Consolidated By Autologous Hematopoietic Stem Cell Transplant

Author

d'Amore, Francesco, primary, Leppä, Sirpa, additional, Silva, Maria Gomes da, additional, Relander, Thomas, additional, Lauritzsen, Grete Fossum, additional, Brown, Peter De Nully, additional, Pezzutto, Antonio, additional, Doorduijn, Jeanette K., additional, Weidmann, Eckhart, additional, van Gelder, Michel, additional, Hoof, Achiel Van, additional, Christiansen, Ilse, additional, Fagerli, Unn Merete, additional, Hagberg, Hans, additional, Lugtenburg, P.J., additional, Walewski, Jan, additional, Wu, Ka Lung, additional, Demuynck, Hilde Maria, additional, Fijnheer, Rob, additional, Christensen, Jacob H., additional, Jankovská, Milada, additional, Josefsson, Pär L., additional, Kluin-Nelemans, Hanneke, additional, Mariz, Jose Mario, additional, Merup, Mats A., additional, Noesslinger, Thomas, additional, Van Den Neste, Eric, additional, Zijlstra, Josée M, additional, Hopfinger, Georg, additional, Prochazka, VIT, additional, Jantunen, Esa, additional, Boudova, Ludmila, additional, Cabecadas, Jose, additional, Chott, Andreas, additional, Delabie, Jan M.A., additional, de Leval, Laurence, additional, Diepstra, Arjan, additional, Karjalainen-Lindsberg, Marja-Liisa, additional, Noergaard, Peter, additional, Rosenwald, Andreas, additional, Rymkiewicz, Grzegorz, additional, Sundström, Christer, additional, Truemper, Lorenz, additional, Wulf, Gerald, additional, Chong, Lauren, additional, Bouska, Alyssa, additional, Smith, Lynette, additional, Gisselbrecht, Christian, additional, Ziepert, Marita, additional, Loeffler, Markus, additional, Liestol, Knut, additional, Steidl, Christian, additional, Gascoyne, Randy D., additional, Scott, David W., additional, Altmann, Bettina, additional, Iqbal, Javeed, additional, Chan, Wing C, additional, and Toldbod, Helle, additional

Published
2018
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