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1. Association of Peri‐Implant Mucosa Dimensions With Emergence Profile Angles of the Implant Prosthesis

Author: Piboon Rungtanakiat, Natchaya Thitaphanich, Martin Janda, Franz Josef Strauss, Mansuang Arksornnukit, and Nikos Mattheos
Subjects: dental implants, emergence angle, implant supracrestal complex, peri‐implant tissue, Dentistry, RK1-715
Abstract: ABSTRACT Objectives The primary aim of this cross‐sectional study was to investigate the association between prosthesis design and peri‐implant mucosa dimensions and morphology. The secondary aim was to investigate associations between mucosal dimensions and the presence of mucositis. Materials and Methods Forty‐seven patients with 103 posterior bone level implants underwent clinical and radiographic examination, including cone beam computer tomography and intraoral optical scanning. Three‐dimensional models for each implant and peri‐implant mucosa were constructed. Vertical mucosa height (TH), horizontal mucosa width at implant platform (TW), and 1.5 mm coronal of the platform (TW1.5), as well as mucosal emergence angle (MEA), deep angle (DA), and total contour angle (TA) were measured at six sites for each implant. Results There was a consistent correlation between peri‐implant mucosa width and height (β = 0.217, p
Published: 2024
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2. Osteoconductive properties of upside-down bilayer collagen membranes in rat calvarial defects

Author: Balazs Feher, Karol Ali Apaza Alccayhuaman, Franz Josef Strauss, Jung-Seok Lee, Stefan Tangl, Ulrike Kuchler, and Reinhard Gruber
Subjects: Collagen membranes, GBR, GTR, Micro-computed tomography, Histology, Histomorphometry, Medicine, Dentistry, RK1-715
Abstract: Abstract Background Bilayer collagen membranes are routinely used in guided bone/tissue regeneration to serve as osteoconductive scaffolds and prevent the invasion of soft tissues. It is recommended to place the membranes with their dense layer towards the soft tissue and their porous layer towards the bony defect area. However, evidence supporting this recommendation is lacking. This study aimed to determine whether the alignment of bilayer collagen membranes has an effect on bone regeneration. Methods In two groups of ten male Sprague-Dawley rats each, a 5-mm calvarial defect was created. Thereafter, the defect was randomly covered with a bilayer, resorbable, pure type I and III collagen membrane placed either regularly or upside-down (i.e., dense layer towards bone defect). After 4 weeks of healing, micro-computed tomography (μCT), histology, and histomorphometry of the inner cylindrical region of interest (4.5 mm in diameter) were performed to assess new bone formation and the consolidation of the collagen membrane in the defect area. Results Quantitative μCT showed similar bone volume (median 8.0 mm3, interquartile range 7.0–10.0 vs. 6.2 mm3, 4.3–9.4, p = 0.06) and trabecular thickness (0.21 mm, 0.19–0.23 vs. 0.18 mm, 0.17–0.20, p = 0.03) between upside-down and regular placement, both leading to an almost complete bony coverage. Histomorphometry showed comparable new bone areas between the upside-down and regularly placed membranes, 3.9 mm2 (2.7–5.4) vs. 3.8 mm2 (2.2–4.0, p = 0.31), respectively. Both treatment groups revealed the same regeneration patterns and spatial distribution of bone with and without collagen fibers, as well as residual collagen fibers. Conclusions Our data support the osteoconductive properties of collagen membranes and suggest that bone regeneration is facilitated regardless of membrane layer alignment.
Published: 2021
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3. Proteomic and genomic analysis of acid dentin lysate with focus on TGF-β signaling

Author: Jila Nasirzade, Zahra Kargarpour, Goran Mitulović, Franz Josef Strauss, Layla Panahipour, Frank Schwarz, and Reinhard Gruber
Subjects: Medicine, Science
Abstract: Abstract Particulate autologous tooth roots are increasingly used for alveolar bone augmentation; however, the proteomic profile of acid dentin lysate and the respective cellular response have not been investigated. Here we show that TGF-β1 is among the 226 proteins of acid dentin lysate (ADL) prepared from porcine teeth. RNA sequencing identified 231 strongly regulated genes when gingival fibroblasts were exposed to ADL. Out of these genes, about one third required activation of the TGF-β receptor type I kinase including interleukin 11 (IL11) and NADPH oxidase 4 (NOX4). Reverse transcription-quantitative polymerase chain reaction and immunoassay confirmed the TGF-β-dependent expression of IL11 and NOX4. The activation of canonical TGF-β signaling by ADL was further confirmed by the phosphorylation of Smad3 and translocation of Smad2/3, using Western blot and immunofluorescence staining, respectively. Finally, we showed that TGF-β activity released from dentin by acid lysis adsorbs to titanium and collagen membranes. These findings suggest that dentin particles are a rich source of TGF-β causing a major response of gingival fibroblasts.
Published: 2021
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4. Clinical effects of probiotic or azithromycin as an adjunct to scaling and root planning in the treatment of stage III periodontitis: a pilot randomized controlled clinical trial

Author: Alicia Morales, Rafael Contador, Joel Bravo, Paola Carvajal, Nora Silva, Franz-Josef Strauss, and Jorge Gamonal
Subjects: Periodontitis, Scaling and root planing, Lactobacillus rhamnosus, Azithromycin, Dentistry, RK1-715
Abstract: Abstract Background The aim of this triple-blind placebo-controlled parallel-arm randomized clinical trial was to evaluate the clinical effects of Lactobacillus rhamnosus SP1 or azithromycin as an adjunct to scaling and root planing (SRP) in patients with stage III periodontitis. Methods Forty-seven systemically healthy participants with stage III periodontitis were recruited. Following SRP, the participants were randomly assigned to one of three treatment modalities; (1) placebo (n = 15), (2) probiotics (n = 16) and (3) antibiotics-azithromycin (n = 16). The participants were monitored at baseline, 3, 6, 9 and 12 months after therapy. Probing pocket depth (PPD), bleeding on probing (BOP), clinical attachment loss (CAL) and plaque accumulation (PI) were evaluated. Results All 47 participants completed the study. At 12 months, all groups showed significant improvements of PPD and PI (p
Published: 2021
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5. Dental caries is associated with severe periodontitis in Chilean adults: a cross-sectional study

Author: Franz-Josef Strauss, Iris Espinoza, Alexandra Stähli, Mauricio Baeza, Ricardo Cortés, Alicia Morales, and Jorge Gamonal
Subjects: Caries, Periodontitis, Prevalence, Co-occurrence, Epidemiology, Chile, Dentistry, RK1-715
Abstract: Abstract Background The co-occurrence of caries and periodontitis and a possible association is still a matter of debate. Thus, the aim of the study was to determine the co-occurrence of caries and periodontitis in Chilean adults. Methods Evaluation of periodontal and dental status in 994 adults (35–44 years old) based on the First Chilean National Examination Survey 2007–2008. The prevalence of caries was defined as the percentage of participants with one or more teeth with untreated caries by using the D component of the DMFT index (DT ≠ 0). The prevalence of periodontitis was determined using standard case definitions for population-based surveillance of periodontitis described by the CDC–AAP. Results Individuals with caries had an approximately 40% higher prevalence of severe (29.3% vs 20.8%, p
Published: 2019
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6. Impact of a caspase inhibitor on alveolar shape changes following tooth extraction

Author: Uwe Yacine Schwarze, Franz Josef Strauss, and Reinhard Gruber
Subjects: Diseases of the musculoskeletal system, RC925-935
Published: 2020
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7. Acid bone lysate activates TGFβ signalling in human oral fibroblasts

Author: Franz Josef Strauss, Alexandra Stähli, Lucian Beer, Goran Mitulović, Valentina Gilmozzi, Nina Haspel, Gerhild Schwab, and Reinhard Gruber
Subjects: Oral Fibroblasts, TGFβ Signaling, Demineralized Bone Matrix, NADPH Oxidase (NOX4), Bone Chips, Medicine, Science
Abstract: Abstract Demineralized bone matrix is a widely used allograft from which not only the inorganic mineral but also embedded growth factors are removed by hydrochloric acid (HCl). The cellular response to the growth factors released during the preparation of demineralized bone matrix, however, has not been studied. Here we investigated the in vitro impact of acid bone lysate (ABL) prepared from porcine cortical bone chips on oral fibroblasts. Proteomic analysis of ABL revealed a large spectrum of bone-derived proteins including TGF-β1. Whole genome microarrays and RT-PCR together with the pharmacologic blocking of TGF-β receptor type I kinase with SB431542 showed that ABL activates the TGF-β target genes interleukin 11, proteoglycan 4, and NADPH oxidase 4. Interleukin 11 expression was confirmed at the protein level by ELISA. Immunofluorescence and Western blot showed the nuclear localization of Smad2/3 and increased phosphorylation of Smad3 with ABL, respectively. This effect was independent of whether ABL was prepared from mandible, calvaria or tibia. These results demonstrate that TGF-β is a major growth factor that is removed upon the preparation of demineralized bone matrix.
Published: 2018
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8. Acid Dentin Lysate Failed to Modulate Bone Formation in Rat Calvaria Defects

Author: Jila Nasirzade, Karol Alí Apaza Alccayhuaman, Zahra Kargarpour, Ulrike Kuchler, Franz Josef Strauss, Layla Panahipour, Carina Kampleitner, Patrick Heimel, Frank Schwarz, and Reinhard Gruber
Subjects: autogenous tooth roots, bone regeneration, rat calvaria defect, collagen membranes, guided bone regeneration, bone augmentation, Biology (General), QH301-705.5
Abstract: Autogenous tooth roots are increasingly applied as a grafting material in alveolar bone augmentation. Since tooth roots undergo creeping substitution similar to bone grafts, it can be hypothesized that osteoclasts release the growth factors stored in the dentin thereby influencing bone formation. To test this hypothesis, collagen membranes were either soaked in acid dentin lysates (ADL) from extracted porcine teeth or serum–free medium followed by lyophilization. Thereafter, these membranes covered standardized 5-mm-diameter critical-size defects in calvarial bone on rats. After four weeks of healing, micro-computed tomography and histological analyses using undecalcified thin ground sections were performed. Micro-computed tomography of the inner 4.5 mm calvaria defects revealed a median bone defect coverage of 91% (CI: 87–95) in the ADL group and 94% (CI: 65–100) in the control group, without significant differences between the groups (intergroup p > 0.05). Furthermore, bone volume (BV) was similar between ADL group (5.7 mm3, CI: 3.4–7.1) and control group (5.7 mm3, CI: 2.9–9.7). Histomorphometry of the defect area confirmed these findings with bone area values amounting to 2.1 mm2 (CI: 1.2–2.6) in the ADL group and 2.0 mm2 (CI: 1.1–3.0) in the control group. Together, these data suggest that acid dentin lysate lyophilized onto collagen membranes failed to modulate the robust bone formation when placed onto calvarial defects.
Published: 2021
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9. Membrane fixation enhances guided bone regeneration in standardized calvarial defects: A pre‐clinical study

Author: Yin‐Zhe An, Franz‐Josef Strauss, Jin‐Young Park, Yu Qin Shen, Daniel Stefan Thoma, and Jung‐Seok Lee
Subjects: Bone Regeneration, Bone Transplantation, Skull, Animals, Periodontics, Membranes, Artificial, Rabbits, X-Ray Microtomography
Abstract: To determine whether collagen membrane (CM) fixation enhances guided bone regeneration in standardized defects.Four 8-mm-diameter defects were surgically made in eight rabbit calvaria, and randomly allocated into four groups: control (empty), unfixed-CM, fixed-CM, and unfixed-CM with bone graft (BG + CM) (positive control). After 1- and 4-week healing periods, the animals were sacrificed and quantitative reverse transcription polymerase chain reaction, micro-computed tomography, and histological outcomes were assessed.At week 1, the expression levels of BMP-2, FGF-2, VEGF, and osteocalcin were significantly higher in the fixed-CM group than in the unfixed-CM and control groups (p .05). Conversely, cathepsin-K was significantly expressed in the unfixed-CM group. No significant differences in expression markers were observed between the fixed-CM and BG + CM groups (p .05). At week 4, new bone formation was significantly higher in the fixed-CM group than the unfixed-CM and control groups (p .05), but similar to the BG + CM group (p .05).CM fixation enhances the expression of osteogenic factors similar to BG + CM, leading to significantly more new bone formation. This suggests that the osteogenic potential is greater when membranes are fixed, thereby limiting the necessity of membrane-supporting materials to enhance bone formation.
Published: 2021

10. Impact of DBBM Fragments on the Porosity of the Calvarial Bone: A Pilot Study on Mice

Author: Ulrike Kuchler, Patrick Heimel, Alexandra Stähli, Franz Josef Strauss, Bernadette Luza, and Reinhard Gruber
Subjects: bone augmentation, guided bone regeneration, osteoclast, biomaterial, DBBM, mouse, Technology, Electrical engineering. Electronics. Nuclear engineering, TK1-9971, Engineering (General). Civil engineering (General), TA1-2040, Microscopy, QH201-278.5, Descriptive and experimental mechanics, QC120-168.85
Abstract: Deproteinized bovine bone mineral (DBBM) is brittle and can break into fragments. Here, we examined whether DBBM fragments have an impact on mice calvarial bone during bone augmentation. DBBM was either randomly crushed (DBBM fragments) or left undisturbed (DBBM granules). Then, DBBM fragments or original DBBM granules were placed onto calvarial bone in 20 BALB/c mice. Following random allocation, ten mice received DBBM fragments and ten mice received original DBBM granules. After fourteen days of healing, micro computed tomography (micro-CT) and histological analysis of the augmented sites were performed. The primary outcome was the porosity of the calvarial bone. The micro-CT analysis revealed that DBBM fragments failed to significantly change the porosity of the calvarial bone as compared with original DBBM granules, despite the slightly higher bone resorption in the DBBM fragment group, 10.3% (CI 6.3–11.6) versus 6.1% (CI 4.1–7.8, p = 0.355), respectively. The cortical bone volume was not altered by DBBM fragments as compared with original DBBM granules, i.e., 79.0% (CI 78.9–81.2) versus 81.5% (CI 80.1–83.3, p = 0.357), respectively. The DBBM fragment group revealed similar bone thickness values as compared with the DBBM granules group, i.e., 0.26 mm (CI 0.23–0.29) versus 0.25 mm (CI 0.22–0.27, p = 0.641), respectively. The histological evaluation supported the micro-CT observations, displaying minor signs of porosity and resorption. The particle-size distribution analysis confirmed a shift towards smaller particle sizes in the DBBM fragment group. These findings suggest that DBBM fragments behave similarly to original DBBM granules in terms of bone morphological changes at augmented sites.
Published: 2020
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11. Effects of Short-Chain Fatty Acids on Human Oral Epithelial Cells and the Potential Impact on Periodontal Disease: A Systematic Review of In Vitro Studies

Author: Gabriel Leonardo Magrin, Franz Josef Strauss, Cesar Augusto Magalhães Benfatti, Lucianne Cople Maia, and Reinhard Gruber
Subjects: short-chain fatty acids, butyrate, epithelial cells, periodontal disease, periodontitis, in vitro, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract: Short-chain fatty acids (SCFA), bacterial metabolites released from dental biofilm, are supposed to target the oral epithelium. There is, however, no consensus on how SCFA affect the oral epithelial cells. The objective of the present study was to systematically review the available in vitro evidence of the impact of SCFA on human oral epithelial cells in the context of periodontal disease. A comprehensive electronic search using five databases along with a grey literature search was performed. In vitro studies that evaluated the effects of SCFA on human oral epithelial cells were eligible for inclusion. Risk of bias was assessed by the University of Bristol’s tool for assessing risk of bias in cell culture studies. Certainty in cumulative evidence was evaluated using GRADE criteria (grading of recommendations assessment, development, and evaluation). Of 3591 records identified, 10 were eligible for inclusion. A meta-analysis was not possible due to the heterogeneity between the studies. The risk of bias across the studies was considered “serious” due to the presence of methodological biases. Despite these limitations, this review showed that SCFA negatively affect the viability of oral epithelial cells by activating a series of cellular events that includes apoptosis, autophagy, and pyroptosis. SCFA impair the integrity and presumably the transmigration of leucocytes through the epithelial layer by changing junctional and adhesion protein expression, respectively. SCFA also affect the expression of chemokines and cytokines in oral epithelial cells. Future research needs to identify the underlying signaling cascades and to translate the in vitro findings into preclinical models.
Published: 2020
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12. Butyrate Decreases ICAM-1 Expression in Human Oral Squamous Cell Carcinoma Cells

Author: Gabriel Leonardo Magrin, Francesca Di Summa, Franz-Josef Strauss, Layla Panahipour, Michael Mildner, Cesar Augusto Magalhães Benfatti, and Reinhard Gruber
Subjects: butyric acid, periodontium, intercellular adhesion molecule-1, oral biology, epithelial cells, in vitro, Biology (General), QH301-705.5, Chemistry, QD1-999
Abstract: Short-chain fatty acids (SCFA) are bacterial metabolites that can be found in periodontal pockets. The expression of adhesion molecules such as intercellular adhesion molecule-1 (ICAM-1) within the epithelium pocket is considered to be a key event for the selective transmigration of leucocytes towards the gingival sulcus. However, the impact of SCFA on ICAM-1 expression by oral epithelial cells remains unclear. We therefore exposed the oral squamous carcinoma cell line HSC-2, primary oral epithelial cells and human gingival fibroblasts to SCFA, namely acetate, propionate and butyrate, and stimulated with known inducers of ICAM-1 such as interleukin-1-beta (IL1β) and tumor necrosis factor-alfa (TNFα). We report here that butyrate but not acetate or propionate significantly suppressed the cytokine-induced ICAM-1 expression in HSC-2 epithelial cells and primary epithelial cells. The G-protein coupled receptor-43 (GPR43/ FFAR2) agonist but not the histone deacetylase inhibitor, trichostatin A, mimicked the butyrate effects. Butyrate also attenuated the nuclear translocation of p65 into the nucleus on HSC-2 cells. The decrease of ICAM-1 was independent of Nrf2/HO-1 signaling and phosphorylation of JNK and p38. Nevertheless, butyrate could not reverse an ongoing cytokine-induced ICAM-1 expression in HSC-2 cells. Overall, these observations suggest that butyrate can attenuate cytokine-induced ICAM-1 expression in cells with epithelial origin.
Published: 2020
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13. The L-shape technique in guided bone regeneration with simultaneous implant placement in the esthetic zone: A step-by-step protocol and a 2-14 year retrospective study

Author: Anina‐Nives Zuercher, Leonardo Mancini, Nadja Naenni, Daniel‐Stefan Thoma, Franz‐Josef Strauss, and Ronald‐Ernst Jung
Subjects: General Dentistry
Abstract: To describe the methodology of the "L-shape" technique in guided bone regeneration (GBR) with simultaneous implant placement and report on the clinical, esthetic, and patient satisfaction outcomes up to 14 years of follow-up.Fourteen patients treated with the "L-shape" technique were included in this retrospective study. The L-shape technique was performed by trimming and placing a soft-type bone block made of deproteinized bovine bone mineral with 10% collagen at the buccal-occlusal aspect of the dental implant. The remaining gaps were filled with deproteinized bovine bone mineral granules and the augmented area was covered with a collagen membrane. The following parameters were recorded: probing depth (PD), bleeding on probing (BOP), plaque index (PI), keratinized tissue width (KT) and marginal bone level (MBL). Esthetic outcomes were assessed according to the pink esthetic score (PES) and the white esthetic score (WES). Patient satisfaction was evaluated by means of a numerical rating scale (0-10). The stability of each augmented site was assessed by measuring the volumetric changes between baseline (crown delivery) and the respective follow-up.A total of 13 maxillary incisors and one maxillary canine in 14 patients were included. The mean follow-up period was 7.7 ± 3.8 years. PES values amounted to 10.7 ± 3.3 and WES to 8.8 ± 1.4. Patient satisfaction reached 9.4 ± 0.8. Mean PD at implant sites were 2.7 ± 0.7 mm while BOP amounted to 15.0 ± 0.2% and Pl to 5.0 ± 0.0%. Volumetric analyses revealed minimal changes at the augmented sites irrespective of the region of interest. Radiographic MBL remained relatively stable.Within the limitation of the present study the L-shape augmentation procedure seems to be a reliable technique when performing GBR with simultaneous implant placement in the esthetic zone. Outcomes encompassed stable clinical and esthetic results accompanied by high levels of patient satisfaction. Future randomized controlled trials are warranted to confirm possible benefits of the L-shape technique over traditional approaches.The L-shape appears to be a simple yet promising technique in GBR with simultaneous implant placement that can easily be translated into clinical practice.
Published: 2022

14. Cover Image

Author: Jung‐Seok Lee, Jin‐Young Park, Hye‐Min Chung, Young Woo Song, and Franz‐Josef Strauss
Subjects: Oral Surgery, General Dentistry
Published: 2022

15. Clinical effects of probiotic or azithromycin as an adjunct to scaling and root planning in the treatment of stage III periodontitis: a pilot randomized controlled clinical trial

Author: Paola Carvajal, Alicia Morales, Joel Bravo, Nora Silva, Franz Josef Strauss, Rafael Contador, Jorge Gamonal, University of Zurich, and Gamonal, Jorge
Subjects: medicine.medical_specialty, Bleeding on probing, 610 Medicine & health, Pilot Projects, Azithromycin, Placebo, Root Planing, law.invention, 10068 Clinic of Reconstructive Dentistry, 03 medical and health sciences, 0302 clinical medicine, Scaling and root planing, Randomized controlled trial, law, Internal medicine, medicine, Humans, Lactobacillus rhamnosus, Periodontitis, General Dentistry, 030304 developmental biology, 0303 health sciences, business.industry, Probiotics, 030206 dentistry, medicine.disease, 3500 General Dentistry, Clinical trial, lcsh:RK1-715, Clinical attachment loss, lcsh:Dentistry, Chronic Periodontitis, Dental Scaling, medicine.symptom, business, Research Article, medicine.drug
Abstract: Background The aim of this triple-blind placebo-controlled parallel-arm randomized clinical trial was to evaluate the clinical effects of Lactobacillus rhamnosus SP1 or azithromycin as an adjunct to scaling and root planing (SRP) in patients with stage III periodontitis. Methods Forty-seven systemically healthy participants with stage III periodontitis were recruited. Following SRP, the participants were randomly assigned to one of three treatment modalities; (1) placebo (n = 15), (2) probiotics (n = 16) and (3) antibiotics-azithromycin (n = 16). The participants were monitored at baseline, 3, 6, 9 and 12 months after therapy. Probing pocket depth (PPD), bleeding on probing (BOP), clinical attachment loss (CAL) and plaque accumulation (PI) were evaluated. Results All 47 participants completed the study. At 12 months, all groups showed significant improvements of PPD and PI (p p = 0.002) and the antibiotic-azithromycin (p = 0.002) group showed a significant reduction of BOP, only the placebo group revealed a significant reduction of CAL at 12 months follow-up (p = 0.003). The number of sites and teeth with PPD ≥ 5, ≥ 6 and ≥ 7 mm were significantly reduced in all groups at 12 months follow-up (p Conclusion The use of probiotics or azithromycin as an adjunct to SRP failed to provide additional benefits in the treatment of stage III periodontitis. The benefits of these two treatment regimes as an adjunct to SRP remain unclear. Trial registration NCT02839408, 10/28/2017, Clinicaltrial.gov.
Published: 2021

16. Treatment of Middle Cerebral Artery Occlusion with Concomitant Partially Thrombosed Aneurysm: a Case Report

Author: Till-Karsten Hauser, Ulrike Ernemann, Michel Klapp Oliger, and Franz Josef Strauss
Subjects: medicine.medical_specialty, business.industry, medicine.medical_treatment, Perforation (oil well), Thrombosed aneurysm, medicine.disease, Revascularization, Surgery, Aneurysm, Concomitant, Occlusion, medicine, cardiovascular diseases, Middle cerebral artery occlusion, Thrombus, business
Abstract: A 68-year-old female with an acute ischemic stroke demanding emergency thrombectomy which was complicated by the presence of an intracranial aneurysm. Computer tomography revealed the occlusion of the right middle cerebral artery with a distal non-ruptured partially thrombosed aneurysm. The treatment consisted in the administration of intravenous recombinant tissue plasminogen activator and the removal of the proximal thrombus via direct aspiration in order to prevent perforation of the distal aneurysm. After the procedure, the clinical symptoms improved significantly indicated by the National Institutes of Health Stroke Scale (NIHSS). The aim of the present case report is, therefore, to suggest a clinical approach to help physicians in the decision-making process for early and safe revascularization in patients with ischemic stroke and intracranial aneurysms.
Published: 2020

17. Caspase inhibitor attenuates the shape changes in the alveolar ridge following tooth extraction: A pilot study in rats

Author: Reinhard Gruber, Franz Josef Strauss, Uwe Yacine Schwarze, University of Zurich, and Gruber, Reinhard
Subjects: 0301 basic medicine, Molar, medicine.medical_specialty, Alveolar Bone Loss, Pilot Projects, 610 Medicine & health, buccal bone, 10068 Clinic of Reconstructive Dentistry, 03 medical and health sciences, socket preservation, 0302 clinical medicine, Atrophy, atrophy, Internal medicine, Alveolar Process, medicine, Alveolar ridge, Animals, Tooth Socket, Caspase, Dental alveolus, tooth extraction, Socket preservation, biology, Chemistry, X-Ray Microtomography, Original Articles, 030206 dentistry, medicine.disease, Caspase Inhibitors, caspase inhibitor, Rats, Resorption, 030104 developmental biology, Endocrinology, ridge preservation, Apoptosis, biology.protein, Periodontics, Original Article, resorption, 3506 Periodontics, osteocytes
Abstract: OBJECTIVE The aim of the study was to determine whether the inhibition of apoptosis via pan-caspase inhibitors can attenuate the changes in the alveolar ridge upon tooth extraction. BACKGROUND Cells undergoing apoptosis might play a central role in the onset of alveolar bone resorption and the ensuing bone atrophy following tooth extraction. Caspases are proteases that regulate apoptotic cell death. It is, therefore, reasonable to hypothesize that blocking apoptosis with pan-caspase inhibitors attenuates the changes in the alveolar ridge following tooth extraction. METHODS In 16 inbred rats, the mandibular first (M1) and second (M2) molars of one side were extracted. Following random allocation, the rats received either a cell-permeable pan-caspase inhibitor or diluent. After a healing period of 10��days, changes in shape and height of the alveolar ridge were examined using geometric morphometrics and linear measurements based on micro-computed tomography. RESULTS Geometric morphometric analysis revealed that the pan-caspase inhibitor prevented major shape changes of the alveolar ridge following M1 tooth extraction (P��
Published: 2020

18. Vertical ridge augmentation feasibility using unfixed collagen membranes and particulate bone substitutes: A 1- to 7-year retrospective single-cohort observational study

Author: Jung‐Seok Lee, Jin‐Young Park, Hye‐Min Chung, Young Woo Song, and Franz‐Josef Strauss
Subjects: Minerals, Bone Regeneration, Bone Transplantation, Dental Implantation, Endosseous, Membranes, Artificial, Alveolar Ridge Augmentation, Bone Substitutes, Guided Tissue Regeneration, Periodontal, Feasibility Studies, Humans, Collagen, Oral Surgery, General Dentistry, Retrospective Studies
Abstract: To determine whether vertical ridge augmentation (VRA) can be obtained through guided bone regeneration (GBR) using exclusively resorbable collagen membranes and particulate bone substitutes without additional stabilization.This study retrospectively examined 22 participants who underwent VRA with staged or simultaneous implant placement. The vertical defects of all participants were filled with particulate bone substitutes and covered with resorbable collagen membranes. The augmented sites were stabilized with unfixed collagen membranes and the flap without any additional fixation. The augmented tissue height was assessed using cone-beam computed tomography at baseline, immediately after surgery, and at annual follow-ups.The vertical bone gain of the 22 augmented sites amounted to 6.48 ± 2.19 mm (mean ± SD) immediately after surgery and 5.78 ± 1.72 mm at 1- to 7-year follow-up. Of the 22 augmented sites, 18 exhibited changes of less than 1 mm, while the other 4 showed changes of greater than 1 mm. Histological observation of three representative cases revealed new bone apposition on the remaining material.The present findings indicate that GBR procedures using exclusively collagen membranes and particulate biomaterials without any additional fixation are feasible options for VRA.
Published: 2022

19. Dental caries is associated with severe periodontitis in Chilean adults: a cross-sectional study

Author: Ricardo Cortés, Alexandra Stähli, Alicia Morales, Jorge Gamonal, Franz Josef Strauss, Mauricio Baeza, and Iris Espinoza
Subjects: Adult, Male, medicine.medical_specialty, Cross-sectional study, Epidemiology, Population, Prevalence, Dentistry, 610 Medicine & health, Dental Caries, Severe periodontitis, 03 medical and health sciences, 0302 clinical medicine, Caries, medicine, Co-occurrence, Humans, Chile, education, Periodontitis, General Dentistry, 030304 developmental biology, 0303 health sciences, education.field_of_study, business.industry, DMF Index, Incidence (epidemiology), 030206 dentistry, medicine.disease, lcsh:RK1-715, stomatognathic diseases, Cross-Sectional Studies, lcsh:Dentistry, Oral and maxillofacial surgery, Female, business, Research Article
Abstract: Background The co-occurrence of caries and periodontitis and a possible association is still a matter of debate. Thus, the aim of the study was to determine the co-occurrence of caries and periodontitis in Chilean adults. Methods Evaluation of periodontal and dental status in 994 adults (35–44 years old) based on the First Chilean National Examination Survey 2007–2008. The prevalence of caries was defined as the percentage of participants with one or more teeth with untreated caries by using the D component of the DMFT index (DT ≠ 0). The prevalence of periodontitis was determined using standard case definitions for population-based surveillance of periodontitis described by the CDC–AAP. Results Individuals with caries had an approximately 40% higher prevalence of severe (29.3% vs 20.8%, p p p Conclusion Dental caries is associated with the severity and prevalence of periodontitis in Chilean adults. Individuals with 3 or more teeth with untreated caries are more likely to suffer from periodontal disease.
Published: 2019

20. Short communication: Cemented implant reconstructions are associated with less marginal bone loss than screw-retained reconstructions at 3 and 5 years of loading

Author: Franz Josef Strauss, Christoph H. F. Hämmerle, Daniel S. Thoma, University of Zurich, and Thoma, Daniel S
Subjects: Radiography, 0206 medical engineering, Bone Screws, Alveolar Bone Loss, Dentistry, 610 Medicine & health, 02 engineering and technology, 03 medical and health sciences, 10068 Clinic of Reconstructive Dentistry, 0302 clinical medicine, Medicine, Humans, Implant loading, Prospective Studies, Dental Implants, business.industry, 3504 Oral Surgery, Significant difference, 030206 dentistry, 020601 biomedical engineering, Peri-Implantitis, Screw retained, Implant, Dental Prosthesis, Implant-Supported, Oral Surgery, business
Abstract: OBJECTIVES To analyse whether there is a difference in marginal bone levels (MBL) and the respective changes between cemented and screw-retained reconstructions at 3 and 5 years of loading. METHODS Radiographic data from 14 prospective multicentre clinical trials following implant loading with fixed cemented (CEM) or screw-retained (SCREW) reconstructions with a 3- to 5-year follow-up were retrieved from a database. MBL and MBL changes were assessed at initiation of implant loading (BL), at 3 (FU-3) and 5 years (FU-5) thereafter. The presence of peri-implantitis was also determined. RESULTS Data from 1,672 implants at BL, 1,565 implants at FU-3 and 1,109 implants at FU-5 were available. The mean MBL amounted to 0.57 mm (SD 0.87) at BL, 0.55 mm (SD 0.86) at FU-3 and 0.65 mm (SD 1.18) at FU-5. At FU-3, the mean MBL was 0.44 mm (SD 0.65) in group CEM and 0.63 mm (SD 0.99) in group SCREW showing a significant difference between the groups (intergroup
Published: 2021

21. Acid bone lysates reduce bone regeneration in rat calvaria defects

Author: Reinhard Gruber, Patrick Heimel, Franz Josef Strauss, Ulrike Kuchler, Reiko Kobatake, Stefan Tangl, University of Zurich, and Gruber, Reinhard
Subjects: Bone Regeneration, Swine, 02 engineering and technology, Culture Media, Serum-Free, Rats, Sprague-Dawley, Random Allocation, Sprague dawley rats, 610 Medicine & health, Metals and Alloys, Collagen membrane, 021001 nanoscience & nanotechnology, Resorption, medicine.anatomical_structure, Intercellular Signaling Peptides and Proteins, Original Article, Female, Collagen, 0210 nano-technology, Materials science, Critical size defect, 0206 medical engineering, Central compartment, Biomedical Engineering, 2506 Metals and Alloys, 2204 Biomedical Engineering, Calvaria, 2503 Ceramics and Composites, Bone and Bones, Biomaterials, Andrology, 10068 Clinic of Reconstructive Dentistry, bone grafts, growth factors, medicine, Animals, Bone regeneration, Wound Healing, Tissue Extracts, Skull, 2502 Biomaterials, Membranes, Artificial, Original Articles, X-Ray Microtomography, 020601 biomedical engineering, Rats, Ceramics and Composites, Hydrochloric Acid, bone allograft, Bone volume
Abstract: Acid bone lysates (ABLs) represent the growth factors and other molecules released during autologous graft resorption. However, the impact of these bone-derived growth factors on the healing of bone defects has not yet been investigated. The aim of the present study was, therefore, to examine the impact of ABLs adsorbed to collagen membranes on bone regeneration. To this end, in 16 female Sprague Dawley rats, a standardized 5-mm-diameter critical size defect on the calvarial bone was created. The defects were covered with collagen membranes that had been soaked either in serum-free media or ABLs followed by lyophilization. After a healing period of 4��weeks, micro-computed tomography (��CT) and histological analyses by means of undecalcified thin ground sections were performed. ��CT analysis of the inner 4��mm of the calvaria defect showed a greater bone defect coverage in the control group when compared to ABL group, 29.8% (confidence interval [CI]: 17.7-50.3) versus 5.6% (CI: 1.0-29.8, p =��.03), respectively. Moreover, we found significantly more absolute bone volume (BV) in the control group when compared to ABL group, 0.59��mm3 (CI: 0.27-1.25) versus 0.07��mm3 (CI: 0.06-0.59, p =��.04), respectively. Histomorphometry confirmed these findings with a relative BV in the central compartment of 14.1% (CI: 8.4-20.6) versus 5.6% (CI: 3.4-7.9, p =��.004), respectively. These findings indicate that bone-derived growth factors contained in ABLs are able to attenuate bone regeneration within collagen membranes.
Published: 2021

22. Proteomic and genomic analysis of acid dentin lysate with focus on TGF-β signaling

Author: Zahra Kargarpour, Jila Nasirzade, Reinhard Gruber, Goran Mitulović, Layla Panahipour, Franz Josef Strauss, Frank Schwarz, University of Zurich, and Gruber, Reinhard
Subjects: Proteomics, 0301 basic medicine, Science, Gingiva, 610 Medicine & health, Article, 03 medical and health sciences, 10068 Clinic of Reconstructive Dentistry, 0302 clinical medicine, Western blot, stomatognathic system, Transforming Growth Factor beta, medicine, Dentin, 1000 Multidisciplinary, Multidisciplinary, NADPH oxidase, medicine.diagnostic_test, biology, Kinase, Chemistry, Gene Expression Profiling, Dental implants, NOX4, RNA, Genomics, 030206 dentistry, Fibroblasts, Molecular biology, 030104 developmental biology, medicine.anatomical_structure, Preclinical research, biology.protein, Phosphorylation, Medicine, Collagen, Signal transduction, Transcriptome, Protein Binding, Signal Transduction
Abstract: Particulate autologous tooth roots are increasingly used for alveolar bone augmentation; however, the proteomic profile of acid dentin lysate and the respective cellular response have not been investigated. Here we show that TGF-β1 is among the 226 proteins of acid dentin lysate (ADL) prepared from porcine teeth. RNA sequencing identified 231 strongly regulated genes when gingival fibroblasts were exposed to ADL. Out of these genes, about one third required activation of the TGF-β receptor type I kinase including interleukin 11 (IL11) and NADPH oxidase 4 (NOX4). Reverse transcription-quantitative polymerase chain reaction and immunoassay confirmed the TGF-β-dependent expression of IL11 and NOX4. The activation of canonical TGF-β signaling by ADL was further confirmed by the phosphorylation of Smad3 and translocation of Smad2/3, using Western blot and immunofluorescence staining, respectively. Finally, we showed that TGF-β activity released from dentin by acid lysis adsorbs to titanium and collagen membranes. These findings suggest that dentin particles are a rich source of TGF-β causing a major response of gingival fibroblasts.
Published: 2021
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23. miRNA-21 deficiency impairs alveolar socket healing in mice

Author: Franz Josef Strauss, Markus Schosserer, Johannes Grillari, Reinhard Gruber, Matthias Hackl, Alexandra Stähli, Reiko Kobatake, Patrick Heimel, Karol Alí Apaza Alccayhuaman, Stefan Tangl, University of Zurich, and Gruber, Reinhard
Subjects: 0301 basic medicine, Pathology, medicine.medical_specialty, mice, Periodontal Ligament, Alveolar Bone Loss, mir‐21, 610 Medicine & health, Bone resorption, 03 medical and health sciences, 10068 Clinic of Reconstructive Dentistry, 0302 clinical medicine, Text mining, bone regeneration, Incisor, microRNA, Alveolar Process, medicine, Animals, Tooth Socket, Bone regeneration, tooth extraction, business.industry, 030206 dentistry, Buccal administration, body regions, MicroRNAs, 030104 developmental biology, medicine.anatomical_structure, Coronal plane, Knockout mouse, Translational Periodontology, Periodontics, Original Article, business, 3506 Periodontics
Abstract: Background MicroRNAs (miRNAs) are small noncoding RNAs demonstrated as critical post‐transcriptional modulators in dental tissues and bone regeneration, particularly miR‐21‐5p. However, the role of miR‐21‐5p in the healing of alveolar sockets following tooth extraction remains unknown. In this study we evaluated the influence of miR‐21‐5p in the healing of alveolar socket after tooth extraction. Methods Eight miR‐21‐5p knockout mice and eight littermate controls underwent tooth extraction of the upper right incisor. After a healing period of 14 days microCT and histological analyses were performed. Results MicroCT analysis showed that the percentage of bone in the extraction socket was significantly higher in the control group than in the miR‐21 knockout mice; either in the coronal (39.0%, CI 31.8 to 48.0 versus 23.0%, CI 17.8 to 35.2, P = 0.03) or in the middle part of the alveolar socket (56.0%, CI 50.9 to 62.5 versus 43.5% CI 28.6 to 54.6, P = 0.03). These differences were not noted in the apical part of the extraction socket. Histological analysis supported the microCT findings. Newly bone volume per tissue volume (BV/TV) was significantly higher in the control group when compared to miR‐21 knockout mice, 27.4% (CI 20.6 to 32.9) versus 19.0% (CI 14.7 to 21.5, P
Published: 2020

24. TGFβ activity released from platelet-rich fibrin adsorbs to titanium surface and collagen membranes

Author: Zahra Kargarpour, Veronika Koller, Jila Nasirzade, Reinhard Gruber, Alexandra Stähli, Tanja Panić-Janković, Goran Mitulović, Layla Panahipour, Francesca Di Summa, Cosima Kaltenbach, Franz Josef Strauss, Heinz Müller, University of Zurich, and Gruber, Reinhard
Subjects: 0301 basic medicine, Cell biology, genetic structures, Gingiva, Gene Expression, lcsh:Medicine, 610 Medicine & health, behavioral disciplines and activities, Fibrin, Article, 03 medical and health sciences, 10068 Clinic of Reconstructive Dentistry, 0302 clinical medicine, Cell Movement, Transforming Growth Factor beta, Platelet-Rich Fibrin, Gene expression, medicine, Humans, Receptor, lcsh:Science, Cells, Cultured, Titanium, 1000 Multidisciplinary, Multidisciplinary, biology, Chemistry, lcsh:R, Osteoblast, 030206 dentistry, Fibroblasts, Platelet-rich fibrin, digestive system diseases, Computational biology and bioinformatics, 030104 developmental biology, Membrane, medicine.anatomical_structure, nervous system, biology.protein, Phosphorylation, Intercellular Signaling Peptides and Proteins, lcsh:Q, Adsorption, Collagen, psychological phenomena and processes, Transforming growth factor
Abstract: Platelet-rich fibrin (PRF) contains a broad spectrum of bioactive molecules that can trigger several cellular responses. However, these molecules along with their upstream responses remain mostly uninvestigated. By means of proteomics we revealed that PRF lysates contain more than 650 proteins, being TGF-β one of the few growth factors found. To uncover the major target genes regulated by PRF lysates, gingival fibroblasts were exposed to lysates obtained from PRF membranes followed by a whole genome array. We identified 51 genes strongly regulated by PRF including IL11, NOX4 and PRG4 which are characteristic TGF-β target genes. RT-PCR and immunoassay analysis confirmed the TGF-β receptor I kinase-dependent increased expression of IL11, NOX4 and PRG4. The PRF-derived TGF-β activity was verified by the translocation of Smad2/3 into the nucleus along with the increased phosphorylation of Smad3. Considering that PRF is clinically used in combination with dental implants and collagen membranes, we showed here that PRF-derived TGF-β activity adsorbs to titanium implants and collagen membranes indicated by the changes in gene expression and immunoassay analysis. Our study points towards TGF-β as major target of PRF and suggest that TGF-β activity released by PRF adsorbs to titanium surface and collagen membranes
Published: 2020

25. Clinical effects of probiotic or azithromycin as an adjunct to scaling and root planing in the treatment of periodontitis stage III: A pilot randomized controlled clinical trial

Author: Nora Silva, Alicia Morales, Rafael Contador, Joel Bravo, Jorge Gamonal, Franz Josef Strauss, and Paola Carvajal
Subjects: Periodontitis, business.industry, Dentistry, medicine.disease, Azithromycin, Adjunct, law.invention, Clinical trial, Probiotic, Scaling and root planing, law, medicine, Stage (cooking), business, medicine.drug
Abstract: Background: The aim of this triple- blind placebo- controlled parallel- arm randomized clinical trial was to evaluate the clinical effects of Lactobacillus rhamnosus SP1 or azithromycin as an adjunct to scaling and root planing (SRP) in patients with stage III periodontitis.Methods: Forty-seven systemically healthy participants with stage III periodontitis were recruited. Following SRP, the participants were randomly assigned to one of three treatment modalities; 1) placebo (n=15), 2) probiotics (n=16) and 3) antibiotics-azithromycin (n=16). The participants were monitored at baseline, 3, 6, 9 and 12 months after therapy. Probing pocket depth (PPD), bleeding on probing (BOP), clinical attachment loss (CAL) and plaque accumulation (PI) were evaluated. Results: All 47 participants completed the study. At 12 months, all groups showed significant improvements of PPD and PI (p Conclusion: The use of probiotics or azithromycin as an adjunct to SRP failed to provide additional benefits in the treatment of stage III periodontitis. The benefits of these two treatment regimes as an adjunct to SRP remain unclear. Trial Registration: NCT02839408, 10/28/2017, Clinicaltrial.gov.
Published: 2020

26. Impact of a caspase inhibitor on alveolar shape changes following tooth extraction

Author: Reinhard Gruber, Franz Josef Strauss, and Uwe Yacine Schwarze
Subjects: Caspase inhibitors, lcsh:Diseases of the musculoskeletal system, Chemistry, Endocrinology, Diabetes and Metabolism, Extraction (chemistry), Orthopedics and Sports Medicine, lcsh:RC925-935, Molecular biology
Published: 2020

27. Digital scanning is more accurate than using a periodontal probe to measure the keratinized tissue width

Author: Jung Seok Lee, Hoi In Jung, Reinhard Gruber, Franz Josef Strauss, Yoon-Sun Jeon, University of Zurich, and Lee, Jung-Seok
Subjects: Periodontium, Oral anatomy, Swine, Intraclass correlation, lcsh:Medicine, 610 Medicine & health, Periodontal probe, Article, 03 medical and health sciences, 10068 Clinic of Reconstructive Dentistry, Imaging, Three-Dimensional, 0302 clinical medicine, 0502 economics and business, Animals, Medicine, Radionuclide imaging, lcsh:Science, Radionuclide Imaging, Periodontitis, Reproducibility, 1000 Multidisciplinary, Multidisciplinary, business.industry, lcsh:R, 05 social sciences, Limits of agreement, 030206 dentistry, Intra-rater reliability, Confidence interval, lcsh:Q, 050211 marketing, business, Nuclear medicine
Abstract: This study aimed to compare the accuracy and reliability of digital versus conventional clinical measurements of the width of keratinized tissue. To this end, the keratinized tissue width was measured at 110 tooth sites in 5 pig jaws. The measurements were made at each site using three-dimensional (3D) scanned images and a periodontal probe. The actual keratinized tissue width was subsequently measured on histologic slides prepared from the same sites, and differences between the histologic slides and the digital and clinical measurements were analyzed to determine their accuracy in two measurement rounds. Furthermore, intrarater and interrater reliabilities were evaluated using the intraclass correlation coefficient (ICC). Here we show that the mean differences (and lower/upper limits of agreement) between the histologic and the digital/clinical measurements were 0.10 mm (−1.34/1.54 mm) and 1.11 mm (−0.69/2.92 mm), respectively, in the first round of measurements (p p p
Published: 2020

28. Impact of DBBM Fragments on the Porosity of the Calvarial Bone: A Pilot Study on Mice

Author: Bernadette Luza, Reinhard Gruber, Franz Josef Strauss, Alexandra Stähli, Ulrike Kuchler, Patrick Heimel, University of Zurich, and Gruber, Reinhard
Subjects: Bone thickness, Dentistry, calvarial bone, 610 Medicine & health, lcsh:Technology, Bone resorption, Article, Bone augmentation, bone augmentation, 03 medical and health sciences, 10068 Clinic of Reconstructive Dentistry, 0302 clinical medicine, Osteoclast, medicine, General Materials Science, lcsh:Microscopy, mouse, 030304 developmental biology, lcsh:QC120-168.85, 0303 health sciences, DBBM, lcsh:QH201-278.5, Chemistry, business.industry, lcsh:T, Micro computed tomography, biomaterial, 030206 dentistry, 2500 General Materials Science, Resorption, Bovine bone, medicine.anatomical_structure, guided bone regeneration, lcsh:TA1-2040, osteoclast, Cortical bone, resorption, lcsh:Descriptive and experimental mechanics, lcsh:Electrical engineering. Electronics. Nuclear engineering, business, lcsh:Engineering (General). Civil engineering (General), lcsh:TK1-9971
Abstract: Deproteinized bovine bone mineral (DBBM) is brittle and can break into fragments. Here, we examined whether DBBM fragments have an impact on mice calvarial bone during bone augmentation. DBBM was either randomly crushed (DBBM fragments) or left undisturbed (DBBM granules). Then, DBBM fragments or original DBBM granules were placed onto calvarial bone in 20 BALB/c mice. Following random allocation, ten mice received DBBM fragments and ten mice received original DBBM granules. After fourteen days of healing, micro computed tomography (micro-CT) and histological analysis of the augmented sites were performed. The primary outcome was the porosity of the calvarial bone. The micro-CT analysis revealed that DBBM fragments failed to significantly change the porosity of the calvarial bone as compared with original DBBM granules, despite the slightly higher bone resorption in the DBBM fragment group, 10.3% (CI 6.3&ndash, 11.6) versus 6.1% (CI 4.1&ndash, 7.8, p = 0.355), respectively. The cortical bone volume was not altered by DBBM fragments as compared with original DBBM granules, i.e., 79.0% (CI 78.9&ndash, 81.2) versus 81.5% (CI 80.1&ndash, 83.3, p = 0.357), respectively. The DBBM fragment group revealed similar bone thickness values as compared with the DBBM granules group, i.e., 0.26 mm (CI 0.23&ndash, 0.29) versus 0.25 mm (CI 0.22&ndash, 0.27, p = 0.641), respectively. The histological evaluation supported the micro-CT observations, displaying minor signs of porosity and resorption. The particle-size distribution analysis confirmed a shift towards smaller particle sizes in the DBBM fragment group. These findings suggest that DBBM fragments behave similarly to original DBBM granules in terms of bone morphological changes at augmented sites.
Published: 2020
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29. The use of platelet-rich plasma to enhance the outcomes of implant therapy: A systematic review

Author: Franz Josef Strauss, Reinhard Gruber, and Alexandra Stähli
Subjects: Sinus Floor Augmentation, Dentistry, 610 Medicine & health, Osseointegration, law.invention, 03 medical and health sciences, 0302 clinical medicine, bone regeneration, Randomized controlled trial, law, Humans, Medicine, Bone regeneration, Review Articles, Platelet-Rich Plasma, business.industry, Clinical study design, Dental Implantation, Endosseous, implant therapy, Alveolar Ridge Augmentation, 030206 dentistry, digestive system diseases, Platelet-rich fibrin, Clinical trial, Treatment Outcome, The 5th EAO Consensus Conference, 7–10 February 2018, Pfäffikon, Schwyz, Switzerland. Guest Editor: Christoph H. F. Hämmerle, 030220 oncology & carcinogenesis, sinus floor elevation, Supplement Article, alveolar ridge preservation, Implant, Oral Surgery, business, platelet‐rich plasma
Abstract: OBJECTIVE To assess the impact of platelet-rich fibrin (PRF) on implant dentistry. The primary focused question was as follows: What are the clinical, histological, and radiographic outcomes of PRF administration for bone regeneration and implant therapy? METHOD A systematic literature search comprised three databases: MEDLINE, EMBASE, and Cochrane followed by a hand search of relevant scientific journals. Human studies using PRF for bone regeneration and implant therapy were considered and articles published up to December 31, 2017 were included. Eligible studies were selected based on the inclusion criteria. Randomized controlled trials (RCT) and controlled clinical trials (CCT) were included. RESULTS In total, 5,963 titles were identified with the search terms and by hand search. A total of 12 randomized controlled trials (RCT) met the inclusion criteria and were chosen for data extraction. Included studies focused on alveolar ridge preservation after tooth extraction, osseointegration process, soft tissue management, bone augmentation, bone regeneration after sinus floor elevation and surgical peri-implantitis treatment. Overall, the risk of bias was moderate or unclear. Nine studies showed superior outcomes for PRF for any of the evaluated variables, such as ridge dimension, bone regeneration, osseointegration process, soft tissue healing. Three studies failed to show any beneficial effects of PRF. No meta-analysis could be performed due to the heterogeneity of study designs. CONCLUSIONS There is moderate evidence supporting the clinical benefit of PRF on ridge preservation and in the early phase of osseointegration. It remains unclear whether PRF can reduce pain and improve soft tissue healing. More research support is necessary to comment on the role of PRF to improve other implant therapy outcomes.
Published: 2018

30. Acid bone lysate activates TGFβ signalling in human oral fibroblasts

Author: Reinhard Gruber, Alexandra Stähli, Nina Haspel, Franz Josef Strauss, Gerhild Schwab, Lucian Beer, Goran Mitulović, and Valentina Gilmozzi
Subjects: Proteomics, 0301 basic medicine, Swine, medicine.medical_treatment, Receptor, Transforming Growth Factor-beta Type I, 0302 clinical medicine, Transforming Growth Factor beta, TGFβ Signaling, 610 Medicine & health, Bone Demineralization Technique, Genome, Multidisciplinary, ABL, biology, medicine.diagnostic_test, Demineralized bone matrix, Chemistry, Gene Expression Regulation, Developmental, Interleukin-11, Interleukin 11, medicine.anatomical_structure, Benzamides, Medicine, Proteoglycans, Bone Chips, Signal Transduction, Science, Dioxoles, Oral Fibroblasts, Article, Demineralized Bone Matrix, 03 medical and health sciences, Proteoglycan 4, Western blot, Cortical Bone, medicine, Animals, Humans, Smad3 Protein, Growth factor, Mouth Mucosa, 030206 dentistry, Fibroblasts, Microarray Analysis, Molecular biology, 030104 developmental biology, Dentin, biology.protein, Cortical bone, Hydrochloric Acid, NADPH Oxidase (NOX4), Transforming growth factor
Abstract: Demineralized bone matrix is a widely used allograft from which not only the inorganic mineral but also embedded growth factors are removed by hydrochloric acid (HCl). The cellular response to the growth factors released during the preparation of demineralized bone matrix, however, has not been studied. Here we investigated the in vitro impact of acid bone lysate (ABL) prepared from porcine cortical bone chips on oral fibroblasts. Proteomic analysis of ABL revealed a large spectrum of bone-derived proteins including TGF-β1. Whole genome microarrays and RT-PCR together with the pharmacologic blocking of TGF-β receptor type I kinase with SB431542 showed that ABL activates the TGF-β target genes interleukin 11, proteoglycan 4, and NADPH oxidase 4. Interleukin 11 expression was confirmed at the protein level by ELISA. Immunofluorescence and Western blot showed the nuclear localization of Smad2/3 and increased phosphorylation of Smad3 with ABL, respectively. This effect was independent of whether ABL was prepared from mandible, calvaria or tibia. These results demonstrate that TGF-β is a major growth factor that is removed upon the preparation of demineralized bone matrix.
Published: 2018

31. Search for supersymmetry in events with one lepton and multiple jets exploiting the angular correlation between the lepton and the missing transverse momentum in proton–proton collisions at s=13TeV

Author: Andreas Hinzmann, Jordan Nash, Giuseppe Fasanella, Sung Keun Park, Marcin Konecki, Artur Lobanov, Nathaniel Pastika, Zukhaimira Zolkapli, Kyle Tos, Martin Flechl, K. Hurtado Anampa, Ioannis Evangelou, Geonhee Oh, Bugra Bilin, Kati Lassila-Perini, Marko Dragicevic, Willard Johns, Shalhout Shalhout, Brandon Allen, Daniele Bonacorsi, Marco Esposito, Petra Merkel, De Hua Zhu, Svenja Schumann, Jorge Chaves, Si Xie, Robert Stone, Tiziano Rovelli, Michal Bluj, Giuseppe Lanza, P. Van Mulders, Andrey Marinov, Iasonas Topsis-Giotis, Alexander Toropin, P. Van Mechelen, Virgil E Barnes, E. A. De Wolf, Alessio Ghezzi, Oleg Markin, A. A. Bin Anuar, Paul Dauncey, Damir Lelas, Olga Driga, Francesca Cenna, Tomasz Frueboes, Oh S. B., J. Smith, David Petyt, W. Van Doninck, Hans Rykaczewski, P. Van Hove, Chiara Mariotti, Marco Monteno, Alexey Volkov, Alessio Boletti, Jie Zhang, Francesca Romana Cavallo, Viktor Savrin, Mitchell Wayne, Karol Bunkowski, Giorgio Maggi, Sadia Khalil, Stefan Grünendahl, Amedeo Staiano, Robert Schöfbeck, Philip Harris, Noemi Beni, K. S. Lee, Maria Isabel Josa, Sungwoong Cho, J. A. Brochero Cifuentes, G. Hamel de Monchenault, Shashikant Dugad, Konstantin Androsov, Tai Sakuma, Kevin Deroover, Andrea Perrotta, Eva Halkiadakis, Fuqiang Wang, Sergey Polikarpov, Justin Pilot, Frank Glege, M. Buttignol, Iurii Antropov, Urs Langenegger, Hallie Trauger, J. C. Ruiz Vargas, Deborah Duchardt, Marco Verzocchi, Nicolas Zaganidis, Brent Yates, David Ja Cockerill, Wolfgang Lange, Gianni Masetti, Erik Gottschalk, Andrea Delgado, Duncan Leggat, Yuriy Pakhotin, N. De Filippis, Alberto Ruiz-Jimeno, Wolfgang Funk, C. Diez Pardos, Alexey Vorobyev, T. du Pree, Johannes Haller, Christian Schomakers, Vadim Oreshkin, James Hirschauer, Vyacheslav Valuev, Cyril X. George, J. P. Fernández Ramos, Kittikul Kovitanggoon, Anterpreet Kaur, Yutaro Iiyama, Intae Yu, Christopher Brainerd, F. Torres Da Silva De Araujo, Nicholas Mucia, Matthieu Marionneau, Arne-Rasmus Draeger, Mehmet Zeyrek, Robert M Harris, Jean-Baptiste Sauvan, Gigi Rolandi, Stefano Argiro, Yang Yang, Matthew Jones, Alexei Raspereza, R. Di Maria, Alexandre Zabi, Vladimir Rekovic, Asif Saddique, Mykola Savitskyi, David Nash, Valeria Botta, R. Stringer, Anna Elliott-Peisert, Vuko Brigljevic, Nicholas Eminizer, Sanjeev Kumar, Crisostomo Sciacca, Maxim Goncharov, Richard D Field, Marco Pieri, Francesco Costanza, David Fehling, Ian R Tomalin, David Saltzberg, S. M. A. Ghiasi Shirazi, Mark Grimes, Thomas Esch, Otman Charaf, Simon Knutzen, Javier Duarte, Jacopo Pazzini, Peter Robmann, Amitabh Lath, Simon Kudella, Gyorgy Bencze, Tiziano Camporesi, Ricardo Lopez-Fernandez, Oh Y. D., Seema Sharma, Louise Skinnari, Vito Palladino, Nural Akchurin, Robert Cousins, Didar Dobur, S. Goy Lopez, Kadir Ocalan, Ketino Kaadze, Frank Jensen, Weifeng Ji, Martina Malberti, David Taylor, P. Martinez Ruiz del Arbol, Ren-Yuan Zhu, Jay Dittmann, Pascal Vanlaer, Luciano Barone, Fabio Ravera, Pawan Kumar Netrakanti, A. De Roeck, S. Fonseca De Souza, Petar Adzic, Aran Garcia-Bellido, Maria Margherita Obertino, Alajos Makovec, Marino Missiroli, Sho Maruyama, Andrius Juodagalvis, Debarati Roy, Muhammad Gul, Engin Eren, Guido Tonelli, Vladimir Palichik, Nicole Ruckstuhl, Austin Ball, Franco Ligabue, Riccardo Paramatti, Andrea Giammanco, Priyanka Kumari, Betty Calpas, Giorgio Apollinari, Ulf Behrens, A. Bermúdez Martínez, Michele Gallinaro, Kenneth Long, Andrea Carlo Marini, Roberto Rossin, Junquan Tao, Giorgia Miniello, Alexander Tapper, Vyacheslav Krutelyov, Peter Wittich, Francesco Fabozzi, Michal Olszewski, Christian Contreras-Campana, Chad Flores, Zhenbin Wu, Bhawna Gomber, Marcello Mannelli, Stefaan Tavernier, Francesco Brivio, Marco Musich, Diego Ciangottini, Elliot Hughes, Andrew Buccilli, Zeljko Antunovic, Claudia-Elisabeth Wulz, Christoph Paus, Charles C. Richardson, Maren Tabea Meinhard, Dimitri Bourilkov, J. W. Gary, Matthias Schröder, James Bowen, Salvatore Nuzzo, Philippe Bloch, O. Gonzalez Lopez, Sh. Jain, Grant Riley, Vladimir Blinov, Nathaniel Odell, Daniele Spiga, Piotr Traczyk, André Holzner, Joschka Lingemann, Anshul Kapoor, Vladimir Karjavin, Andrew Whitbeck, Viktor Veszpremi, Abdulla Abdulsalam, Giovanni Polese, Markus Stoye, Wolfgang Waltenberger, H. El Mamouni, Piergiulio Lenzi, Arthur Moraes, Kai Yi, A. Castaneda Hernandez, J. Ellison, S. Di Guida, R. Teixeira De Lima, W. A. T. Wan Abdullah, Maria Hempel, Kyungwook Nam, Erik Butz, Hannes Mildner, Robert Fischer, Charles Mueller, Benjamin Mesic, Kunal Kothekar, Teruki Kamon, David Jonathan Hofman, Kerstin Borras, Dmitry Elumakhov, James Buchanan, Bruno Casal, Pawandeep Jandir, Sa. Jain, Emmanuel Olaiya, Alexander Schmidt, Vytautas Dudenas, Nadir Daci, Nikola Godinovic, Hualin Mei, Juan Garcia-Ferrero, Ulrich Heintz, J. Piedra Gomez, Deborah Pinna, Caterina Vernieri, Souvik Das, Gian Mario Bilei, Márton Bartók, Jingzhou Zhao, Haneol Lee, David Colling, Natalia Lychkovskaya, Monika Grothe, K. Goulianos, Timo Peltola, Pedro Silva, J. Mejia Guisao, Jamal Rorie, Jason Gilmore, Regina Demina, Reyer Band, Stephen Sanders, Dominick Olivito, Colin Jessop, Richard Vidal, Matthias Kasemann, Lorenzo Bianchini, Altan Cakir, Paolo Meridiani, Tomislav Seva, Aron Soha, B. Chazin Quero, Simon Kurz, Maksym Titov, Daniel Klein, Herbert Rohringer, Federico Ferri, Benedikt Freund, Douglas Berry, Marco Paganoni, Don Lincoln, W. De Boer, Jory Sonneveld, Hafeez R Hoorani, Daniel John Karmgard, Manfred Jeitler, Fabrizio Palla, Andrew Melo, Andrew Evans, Dong-Chul Son, Liliana Teodorescu, A. G. Stahl Leiton, Adolf Bornheim, Aaron Bundock, Katerina Lipka, Martin Kirakosyan, Rami Kamalieddin, Shabnam Jabeen, Benedikt Vormwald, Alessandro Montanari, David Sheffield, Kevin Mcdermott, Dmytro Kovalskyi, Gyorgy Vesztergombi, Ali Harb, Luca Malgeri, Luc Pape, S. Mukhopadhyay, Vassili Kachanov, C. Royon, Moritz Guthoff, René Caspart, Igor Azhgirey, Rajarshi Bhattacharya, Frank Jm Geurts, I. Van Parijs, H. S. Chen, Elisabetta Manca, Bobak Hashemi, Tom Cornelis, Shivali Malhotra, Gunter Quast, Tanmay Mudholkar, Arun Kumar, Helena Bialkowska, Erhan Gülmez, Kaori Maeshima, Aurelijus Rinkevicius, Martin Erdmann, Sourabh Dube, Matthew Walker, S. Erdweg, Howard Wells Wulsin, Ibrahim Soner Zorbakir, Paola Salvini, Metin Yalvac, Stephan Lammel, Tagir Aushev, Marcos Fernandez, Florian Beaudette, Marek Walczak, Wesley H Smith, James Faulkner, Michael Schmitt, Carlo Rovelli, Joosep Pata, Alexander Nikitenko, Colin Bernet, Nadia Pastrone, Silvio Donato, Ezio Torassa, Ugur Kiminsu, Christoph Grab, G. Zevi Della Porta, Felix Bachmair, Georgia Karapostoli, Henning Kirschenmann, Edouard Boos, Ennio Monteil, Aldo Penzo, Nicolas Tonon, Vladimir Popov, Matteo Cremonesi, Sergey Petrushanko, Patricia McBride, Krzysztof Doroba, Alexander Spiridonov, Francesca Nessi-Tedaldi, Ron Lipton, F. Mohamad Idris, M. Olmedo Negrete, Jian Sun, Artur Kalinowski, Myriam Schönenberger, Dmitry Philippov, Jaehoon Lim, Nitish Dhingra, Shubham Pandey, Andrea Castro, Thomas Klijnsma, Aidan Randle-Conde, Mikhail Gavrilenko, Juska Pekkanen, M. Franco Sevilla, Hugo Delannoy, Daniel Noonan, Olaf Behnke, V. Calvelli, Marcella Diemoz, Mareike Meyer, Shawn Williamson, Owen Baron, Mengyao Shi, Steve Schnetzer, Saranya Ghosh, Klaas Padeken, Dominik Haitz, Renato Campanini, Mohsen Khakzad, Suneel Dutt, Roberto Dell'Orso, Sergey Troshin, Meng Wang, David D'Enterria, Daniele Pedrini, Benedikt Maier, Konrad Deiters, G. P. Van Onsem, Anna Cimmino, J. Yelton, Shirin Chenarani, Martti Raidal, Pamela Klabbers, Burin Asavapibhop, Aram Avetisyan, Jorge Luis Rodriguez, Dylan Rankin, Andrew Brinkerhoff, Thomas Ferguson, J. Suarez Gonzalez, Yanchu Wang, Harry Cheung, Andrew Johnson, Peter Schleper, Zhen Hu, Keith Ulmer, Maciej Górski, Antonio Rossi, Anna Kropivnitskaya, Samuel Bein, Daniel Spitzbart, Giuseppe Barbagli, Simone Pigazzini, Jasvinder A. Singh, Vladimir Chekhovsky, Pablo Garcia-Abia, Alain Hervé, Yuri Skovpen, Carlos Lourenco, Pete Markowitz, Bora Akgun, Manoj Jha, M. 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De Visscher, Alessandra Fanfani, Christian Barth, Daniele Fasanella, Lea Caminada, Adrian Byszuk, Frixos A Triantis, Andrew Askew, Gurpreet Singh, Styliani Orfanelli, Paul Kyberd, Karl Gill, R. Frühwirth, Ana Ovcharova, Anna Julia Zsigmond, Andrea Venturi, Yacine Haddad, Antonio Ranieri, S. Sanchez Cruz, Ta-Wei Wang, Piet Verwilligen, Mauro Menichelli, Simon Regnard, Stefan Spanier, Brian Dorney, Luca Perniè, Roland Horisberger, Yuan Chao, Georgios Mavromanolakis, Leonid Levchuk, Mariarosaria D'Alfonso, Mario Galanti, Zoltan Szillasi, Michele Arneodo, Andrey Uzunian, Elisa Manoni, Christopher Anelli, Luca Scodellaro, Christos Roskas, Christopher Palmer, Annika Vanhoefer, Alice Bean, Brieuc Francois, Paul Edmund Karchin, Thomas Madlener, G. F. Chen, Balazs Ujvari, Yuri Musienko, Aaron Levine, Francesco Fienga, Shervin Nourbakhsh, Maria Cepeda, Qiang Li, Akram Khan, Jorgen D'Hondt, A. Pérez-Calero Yzquierdo, Nicolas Chanon, Helena Malbouisson, Nabarun Dev, Alex J. Barker, L. F. Chaparro Sierra, Thomas Lenzi, Min Suk Kim, Vipin Bhatnagar, Camelia Mironov, Nadeesha Wickramage, Anna Zanetti, Georg Sieber, Ilknur Hos, J. N. Butler, Genius Walia, Salvatore Buontempo, Paul Avery, Salavat Abdullin, Lisa Benato, Paolo Lariccia, Stefan Piperov, Quentin Python, Randy Ruchti, Joe Incandela, Luca Cadamuro, Virginia Azzolini, Jasper Lauwers, Zheng Wang, Wajid Ali Khan, N. Majumdar, Inna Kucher, Aysen Tatarinov, Ping Tan, M. De Palma, Sarah Beranek, Tuure Tuuva, Elizabeth Kennedy, Margaret Zientek, Unki Yang, Ozgun Kara, Ramkrishna Sharma, Daniel Gastler, Seth Moortgat, Hong Ni, L. Alunni Solestizi, Muhammad Waqas, T. R. Fernandez Perez Tomei, Predrag Milenovic, Peter R Hobson, E. Eskandari Tadavani, Sudarshan Paramesvaran, Victor Daniel Elvira, Bilal Kiani, Alexander Snigirev, Stephane Cooperstein, Philipp Pigard, James Alexander, Lukasz Kreczko, M. Csanad, Alessio Magitteri, F. 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Hou, Ferdinando Giordano, Paul Sheldon, Yuichi Kubota, Andreas Albert, Alexander Dierlamm, Michal Szleper, Philippe Gras, Roberto Chierici, Chia-Ming Kuo, Jack Wright, Candan Dozen, Robert Ciesielski, Michael Wayne Arenton, Sean Kalafut, Shalini Thakur, James John Brooke, Stefka Stoykova, Martina Ressegotti, Fabrizio Gasparini, Michele Selvaggi, Gulsen Onengut, Viktor Matveev, Clemens Lange, Santiago Folgueras, George Alverson, Roman Kogler, Benjamin Kreis, Mark Pesaresi, Analu Custódio, Markus Seidel, Vineet Kumar, Seth Cooper, Semra Turkcapar, Linda Finco, Keith Rose, Mingshui Chen, Nikita Beliy, Matthias Komm, Arnab Purohit, Scott Thomas, Piero Giorgio Verdini, S. W. Lee, Matevz Tadel, Viola Sordini, Erika Garutti, Giancarlo Mantovani, Carlo Battilana, Sezen Sekmen, Charles Ferraioli, H. 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De La Cruz-Burelo, Attila Racz, Roberta Arcidiacono, Christian Schnaible, Jonathan Fulcher, Anatoli Pashenkov, Mikhail Ignatenko, Jelena Luetic, Tapio Lampén, Andrzej Pyskir, Ece Aşılar, Lei Feng, Fabrizio Fabbri, Claudia Cecchi, Kamuran Dilsiz, Steven Wasserbaech, Eleni Ntomari, Seema Bahinipati, Paolo Rumerio, Lorenzo Uplegger, Jan Hoss, William T. Ford, Christian Autermann, Christoph Wissing, Norraphat Srimanobhas, Dermot Moran, Joachim Mnich, Andreas Mussgiller, Fotios Ptochos, Kenneth Bloom, Thomas Perry, M. De Mattia, Riccardo Bellan, Michael Gardner, Hannsjoerg Artur Weber, Gordon H. Hanson, Geonmo Ryu, M. Vidal Marono, Subir Sarkar, Suresh C Tonwar, Sylvie Braibant-Giacomelli, Sean-Jiun Wang, Claudio Grandi, John Stupak, Raffaele Gerosa, Huaqiao Zhang, Alexander Ledovskoy, Vincent J Smith, J. M. Grados Luyando, Sébastien Gadrat, Mayda Velasco, M. Melo De Almeida, Jian-Guo Bian, Andrey Pozdnyakov, A. Quintario Olmeda, Thomas Kress, Maria Elena Pol, Oliver Pooth, Jan Steggemann, Andrés Cabrera, Marc Stöver, Laszlo Gutay, Pallabi Das, Georg Steinbrück, Barbara Clerbaux, Marcello Maggi, Davide Piccolo, Vincenzo Monaco, Cristina Tuve, Miroslav Finger, Borislav Pavlov, Csaba Hajdu, Emyr Clement, Mario Masciovecchio, Stefano Marcellini, Huilin Qu, Ari Lee, James Letts, Gino Bolla, M. Barrio Luna, Mateusz Zarucki, Rylan Conway, Matthias Ulrich Mozer, Johannes Brandstetter, Alexander Malakhov, Efe Yazgan, Günter Flügge, Qiao Xu, Tyler Ruggles, Robert Clare, Patrizia Azzi, Thomas Hebbeker, Paul Lecoq, Ksenia Shchelina, Albert M. Sirunyan, M. Centis Vignali, M. Weber, Frans Meijers, Edward Scott, Kristian Harder, Vladimir Petrov, Thomas N. Williams, Stefan Wayand, Simone Paoletti, Rebecca Lane, Suchandra Dutta, Giulio Mandorli, Anne-Marie Magnan, Wagner Carvalho, Hongbo Liao, Terhi Jarvinen, Greg Landsberg, Cécile Caillol, Sw. Banerjee, Manjit Kaur, J. M. Vizan Garcia, Francesco Fiori, Philippe Busson, Pedrame Bargassa, Nick Amin, Nikolay Voytishin, Kira Burt, Merve Nazlim Agaras, Mehar Ali Shah, Thomas Peiffer, Stefano Colafranceschi, Siarhei Shulha, Paolo Gunnellini, Batool Safarzadeh, Juliet Ritchie Patterson, Joao Varela, Leander Litov, Jean-Pierre Merlo, Rocky Bala Garg, Joanne Cole, Eija Tuominen, Luigi Fiore, Lucia Perrini, Patrick Connor, Roberval Walsh, Giovanna Selvaggi, Daniel Abercrombie, Gagan Bihari Mohanty, Gabor Istvan Veres, Alexandre Mertens, Sarah Catherine Eno, Jan-Frederik Schulte, Hugues Brun, Pieter Everaerts, Titas Roy, Alexx Perloff, Roman Ryutin, Federica Primavera, Roberto Carlin, Pierre Depasse, Vyacheslav Klyukhin, M. Van De Klundert, R. Kunnawalkam Elayavalli, Chris Lucas, Dustin Stolp, Lorenzo Viliani, Kurt Jung, Tariq Aziz, and Dave M Newbold
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Gluino, Muon, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Supersymmetry, 01 natural sciences, 7. Clean energy, Chargino, Pair production, 0103 physical sciences, Neutralino, High Energy Physics::Experiment, Neutrino, 010306 general physics, Lepton
Abstract: Results are presented from a search for supersymmetry in events with a single electron or muon and hadronic jets. The data correspond to a sample of proton–proton collisions at √s = 13 TeV with an integrated luminosity of 35.9fb^(-1), recorded in 2016 by the CMS experiment. A number of exclusive search regions are defined according to the number of jets, the number of b-tagged jets, the scalar sum of the transverse momenta of the jets, and the scalar sum of the missing transverse momentum and the transverse momentum of the lepton. Standard model background events are reduced significantly by requiring a large azimuthal angle between the direction of the lepton and of the reconstructed W boson, computed under the hypothesis that all of the missing transverse momentum in the event arises from a neutrino produced in the leptonic decay of the W boson. The numbers of observed events are consistent with the expectations from standard model processes, and the results are used to set lower limits on supersymmetric particle masses in the context of two simplified models of gluino pair production. In the first model, where each gluino decays to a top quark–antiquark pair and a neutralino, gluino masses up to 1.8 TeV are excluded at the 95% CL. The second model considers a three-body decay to a light quark–antiquark pair and a chargino, which subsequently decays to a W boson and a neutralino. In this model, gluinos are excluded up to 1.9 TeV.
Published: 2018

32. Search for supersymmetry with Higgs boson to diphoton decays using the razor variables at s=13TeV

Author: Morgan Lethuillier, Yasar Onel, Julie Malcles, Fengwangdong Zhang, Yi-ting Duh, Ignacio Redondo, Benjamin Stieger, Hyun-Chul Kim, Boris Grynyov, Shengquan Tuo, Abhigyan Dasgupta, Yurii Maravin, Markus Stoye, Kai Yi, Zviad Tsamalaidze, Nikolai Skatchkov, Louis Antonelli, A. Castaneda Hernandez, Martin Flechl, K. Hurtado Anampa, Jian Wang, Iasonas Topsis-Giotis, Alexander Toropin, Michael Albrow, Vladimir Chekhovsky, Virgil E Barnes, Caleb Fangmeier, Vladimir Gavrilov, Aleko Khukhunaishvili, Sonaina Undleeb, Igor Miagkov, Quentin Ingram, Igor Vorobiev, Martin Delcourt, Pablo Garcia-Abia, Hamed Bakhshiansohi, Francesco Fallavollita, Julie Managan Hogan, Markus Friedl, A. C. Le Bihan, Stephan Linn, Yu S. S., Marguerite Tonjes, David Mark Raymond, Olivier Bondu, Alain Hervé, Yuri Skovpen, A. Di Mattia, Alessio Ghezzi, Brent Yates, Esteban Curras, Christophe Delaere, Jose Monroy, Lucas Brito, Panos A Razis, Steven R. Simon, John Gabriel Acosta, Ivan Vila, S. Carrillo Moreno, Johannes Haller, Alex Kamenev, Victor Kim, Christian Schomakers, Laura Borrello, Paul Lujan, Vadim Oreshkin, Hannes Jung, Alexander Zhokin, J. S. H. Lee, Martijn Mulders, Willem Verbeke, Armando Lanaro, Nicholas Eminizer, A. Rose, Tao Huang, Peisen Ma, Daniel Bloch, Cameron Bravo, Vivek Sharma, Adrien Caudron, Fabio Ravera, Maren Tabea Meinhard, Alexander Dierlamm, Anna Colaleo, Kamal Lamichhane, Nadja Strobbe, Suman Chatterjee, Jean-Laurent Agram, M. Foerster, Giuseppe Benedetto Cerati, Nikola Godinovic, Hualin Mei, Altan Cakir, Anthony Moeller, Jim Freeman, Tomas Lindén, Michal Szleper, Philippe Gras, Martino Margoni, N. Van Remortel, Paolo Meridiani, Tomislav Seva, Aron Soha, Simon Kurz, Stavros Mallios, Johannes Wittmann, James D. Olsen, Malte Hoffmann, Alice Florent, Roberto Chierici, Chia-Ming Kuo, Daniele Pedrini, Benedikt Maier, Jack Wright, René Caspart, Rajarshi Bhattacharya, Elisabetta Manca, Konrad Deiters, Xuyang Gao, Carlo Civinini, Christoph Grab, Anna Cimmino, Pawandeep Jandir, P. De Castro Manzano, Aristotelis Kyriakis, Andreas Hinzmann, Lieselotte Moreels, Pushpalatha C Bhat, Jennifer A. Smith, Henning Kirschenmann, Edouard Boos, Ferenc Sikler, Dayong Wang, Mauro Verzetti, Amitabh Lath, Simon Kudella, Gyorgy Bencze, J. Yelton, Shirin Chenarani, Jozsef Molnar, Dmitry Shtol, Gérald Grenier, Alessandro Braghieri, Johannes Schulz, Andrea Triossi, Christoph Schwick, Richard Lander, Simone Gennai, Candan Dozen, C. Diez Pardos, Robert Ciesielski, Michael Wayne Arenton, Sean Kalafut, Jacopo Bernardini, Tobias Pook, Jay Hauser, A. Vilela Pereira, Andrei Starodumov, Florian Kassel, Michael Brodski, Roberto Castello, Andrey Popov, Lawrence Sulak, Dimitri Bourilkov, Mario Kadastik, R. 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Gomez Ceballos, Nikos Varelas, Helen F Heath, Keith Rose, Mingshui Chen, Susan Gascon, Gunther Roland, Lovedeep Kaur Saini, Xin Chen, Teresa Rodrigo, Elisabetta Gallo, Vincenzo Ciriolo, Alexis Pompili, Roger Rusack, Marc Dejardin, Nathan Kellams, Robin Aggleton, Ferhat Ozok, T. A. Gómez Espinosa, H. Van Haevermaet, Daniele Trocino, Silvia Maselli, Sam Harper, Maria Hempel, Zeljko Antunovic, Shuichi Kunori, Paolo Azzurri, Nikita Beliy, Günther Dissertori, Yi Chen, Johannes Hauk, Teresa Lenz, M. L. Vesterbacka Olsson, Matthias Komm, Arnab Purohit, Jaehyeok Yoo, Laurent Mirabito, Daniel Gonzalez, C. Beirão Da Cruz E Silva, Steven Lowette, Antoni Shtipliyski, Scott Thomas, Piero Giorgio Verdini, Alessandro Degano, Rishika Bhardwaj, S. W. Lee, Matevz Tadel, Seon-hee Seo, Dominique Gigi, E. M. Da Costa, Erich Schmitz, Benoit Courbon, C. Martinez Rivero, János Karancsi, Ali Celik, I. Gonzalez Caballero, Shabnam Jabeen, Lutz Feld, Claudia-Elisabeth Wulz, Christoph Paus, Tommaso Boccali, Louie Corpe, Stephen Wimpenny, Henning Flacher, Shalini Thakur, Wolfgang Waltenberger, Shahram Rahatlou, Christopher Mcginn, Raffaello D'Alessandro, Slawek Tkaczyk, Olivier Davignon, Dmitri Konstantinov, Yue Shi Lai, Illia Khvastunov, Winston Ko, I. De Bruyn, Reza Goldouzian, Metin Yalvac, Giorgio Apollinari, Nikolaos Manthos, Ulf Behrens, Cecilia Elena Gerber, Christian Laner, Martin Grunewald, Charles Mueller, J. Piedra Gomez, Stephan Lammel, Robert Hirosky, Tagir Aushev, Hugo Delannoy, Lea Caminada, Benjamin Mesic, Kunal Kothekar, Piergiulio Lenzi, Arthur Moraes, Mohd Nizam Yusli, Federico Preiato, Oleg Prokofyev, Wolfram Erdmann, Nicolo Cartiglia, Atanu Modak, James John Brooke, Stefka Stoykova, Viola Sordini, S. 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De Boer, Jory Sonneveld, Hafeez R Hoorani, David Stickland, Daniel John Karmgard, Manfred Jeitler, Fabrizio Palla, S. Ventura, Andrew Melo, Owen Baron, Mengyao Shi, Daniel Pitzl, Lo K. H., Steve Schnetzer, Saranya Ghosh, Klaas Padeken, Renato Campanini, Joaquin Emilo Siado, Carlos Lourenco, Alexander Nehrkorn, Maksat Haytmyradov, Paolo Montagna, Luca Perrozzi, Manfred Krammer, Othmane Bouhali, Carlos Erice, Kevin Sung, Florent Lacroix, Semiray Girgis, David Mason, Luigi Moroni, Luca Lista, James G Branson, Jesus Marco, Sebastian Baur, David Krofcheck, Jonathan Hollar, J. P. Fernández Ramos, Willis Lin, Anirban Saha, Ekaterina Avdeeva, Roberto Leonardi, Markus Merschmeyer, Arie Bodek, Ozlem Kaya, Sevil Salur, A. Baden, Gino Bolla, M. Barrio Luna, Mateusz Zarucki, P. Martinez Ruiz del Arbol, Rylan Conway, J. F. de Trocóniz, Matthias Ulrich Mozer, A. Morelos Pineda, Johannes Brandstetter, Alexander Malakhov, Efe Yazgan, Günter Flügge, Qiao Xu, M. Naimuddin, Tyler Ruggles, Robert Clare, Patrizia Azzi, Thomas Hebbeker, Paul Lecoq, A. De Roeck, A. David, Ksenia Shchelina, Albert M. Sirunyan, T. Verlage, M. Weber, A. De Wit, Frans Meijers, Edward Scott, Kristian Harder, Vladimir Petrov, Thomas N. Williams, Stefan Wayand, Simone Paoletti, Rebecca Lane, Suchandra Dutta, Giulio Mandorli, Anne-Marie Magnan, Wagner Carvalho, Hongbo Liao, Terhi Jarvinen, Greg Landsberg, Cécile Caillol, Manjit Kaur, Francesco Fiori, Philippe Busson, Pedrame Bargassa, Nick Amin, Nikolay Voytishin, Kira Burt, Merve Nazlim Agaras, Mehar Ali Shah, Thomas Peiffer, Stefano Colafranceschi, Siarhei Shulha, Paolo Gunnellini, Batool Safarzadeh, Juliet Ritchie Patterson, Joao Varela, Leander Litov, Jean-Pierre Merlo, Rocky Bala Garg, Joanne Cole, Eija Tuominen, Luigi Fiore, Lucia Perrini, Patrick Connor, Roberval Walsh, Giovanna Selvaggi, Daniel Abercrombie, Gagan Bihari Mohanty, Gabor Istvan Veres, Alexandre Mertens, Sarah Catherine Eno, Jan-Frederik Schulte, Minkyoo Choi, Hugues Brun, Pieter Everaerts, Titas Roy, Alexx Perloff, Roman Ryutin, Federica Primavera, Pierre Depasse, Vyacheslav Klyukhin, M. Van De Klundert, Chris Lucas, Dustin Stolp, Lorenzo Viliani, Kurt Jung, Gabriella Pugliese, I. Van Parijs, Kevin Lannon, G. Della Ricca, Guenakh Mitselmakher, Jordan Damgov, D. Di Croce, Peter Hansen, Kisung Lee, Jay Mathew Lawhorn, Claude Amsler, Zhoudunming Tu, Laurent Favart, Kristof Pauwels, Cristian Pena, Thomas Reis, Martin Lipinski, Frank Würthwein, Manas Maity, Alexi Mestvirishvili, Ulrich Goerlach, A. Gribushin, Steve Nahn, Paolo Capiluppi, James Rohlf, Carlos Avila, Sergei Bitioukov, Ricardo Eusebi, Mithat Kaya, Giorgia Rauco, Suyong Choi, Etiennette Auffray, Maurizio Biasini, Sinan Sagir, Marta Felcini, Y. Mohammed, Mark Derdzinski, Nikitas Loukas, Mani Tripathi, Rachel Bartek, Marco Peruzzi, L. Lloret Iglesias, Usama Hussain, Owen Rosser Long, Warren Clarida, Cesare Calabria, Nicola Amapane, Matteo Sani, Andreas Nowack, Andrew Ackert, Elif Asli Yetkin, Koushik Mandal, Paraskevas Sphicas, Alberto Benvenuti, Maria Agnese Ciocci, Dave Pellett, Marko Kovac, Maria Florencia Canelli, Fabrizio Ferro, Thomas Ferbel, Dan Green, Marta Ruspa, Stepan Obraztsov, Thong Nguyen, Till Arndt, Shao Min Tan, Roberto Sacchi, Tejinder Virdee, Nicolò Tosi, Camilla Galloni, Seth Conrad Zenz, I. Heredia-De La Cruz, Andrew Godshalk, Vincenzo Daponte, M. Vidal Marono, Daniele Marconi, S. De Visscher, Julia Thom, Finn Rebassoo, Volker Blobel, Joshua Hardenbrook, Lucia Silvestris, Neeti Parashar, Klaus Rabbertz, M. Hamer, Sebastiano Albergo, Igor Lokhtin, Zachary Lesko, Robert M Brown, Gobinda Majumder, Stefano Ragazzi, Jane Nachtman, R. Gonzalez Suarez, Sergio F Novaes, Samet Lezki, and R. Reyes-Almanza
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Large Hadron Collider, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Electroweak interaction, Supersymmetry, 7. Clean energy, 01 natural sciences, Lightest Supersymmetric Particle, Bottom quark, Nuclear physics, 0103 physical sciences, Neutralino, Higgs boson, High Energy Physics::Experiment, Goldstino, 010306 general physics
Abstract: An inclusive search for anomalous Higgs boson production in the diphoton decay channel and in association with at least one jet is presented, using LHC proton–proton collision data collected by the CMS experiment at a center-of-mass energy of 13 TeV and corresponding to an integrated luminosity of 35.9fb^(−1). The razor variables M_R and R^2, as well as the momentum and mass resolution of the diphoton system, are used to categorize events into different search regions. The search result is interpreted in the context of strong and electroweak production of supersymmetric particles. We exclude bottom squark pair-production with masses below 450 GeV for bottom squarks decaying to a bottom quark, a Higgs boson, and the lightest supersymmetric particle (LSP) for LSP masses below 250 GeV. For wino-like chargino–neutralino production, we exclude charginos with mass below 170 GeV for LSP masses below 25 GeV. In the GMSB scenario, we exclude charginos with mass below 205 GeV for neutralinos decaying to a Higgs boson and a goldstino LSP with 100% branching fraction.
Published: 2018

33. Search for the pair production of third-generation squarks with two-body decays to a bottom or charm quark and a neutralino in proton–proton collisions at s=13TeV

Author: Lu R. S., Stephane Perries, Carsten Heidemann, Costas Foudas, Devdatta Majumder, Henning Flacher, Dominique Gigi, Nikolaos Manthos, Christian Laner, Martin Grunewald, Benoit Courbon, Raffaello D'Alessandro, J. Piedra Gomez, Andrei Sobol, Federico Preiato, Oleg Prokofyev, Wolfram Erdmann, Gabriella Pasztor, Fengwangdong Zhang, S. Afanasiev, Mara Senghi Soares, Serguei Ganjour, Silvia Taroni, Aytul Adiguzel, A. Álvarez Fernández, Boris Grynyov, Ahmad Borzou, Ketino Kaadze, Shengquan Tuo, Darien Wood, Jyothsna Rani Komaragiri, Nicholas John Hadley, Mark Turner, Jehad Mousa, T. R. Fernandez Perez Tomei, Raphael Friese, Karl Matthew Ecklund, A. Rizzi, Maral Alyari, Claudia Pistone, Emanuela Barberis, Nicolo Magini, Michael Dittmar, Andreas Psallidas, C. Vander Velde, E. Carrera Jarrin, Douglas Wright, Andrew Carnes, Jordan Tucker, Abhigyan Dasgupta, Nikolai Skatchkov, Louis Antonelli, Christian Contreras-Campana, E. W. Vaandering, V. Re, André Holzner, Joschka Lingemann, S. Abu Zeid, A. Richards, J. D. Ruiz Alvarez, Wolfgang Adam, R. Kunnawalkam Elayavalli, Steven Kaplan, J. A. Brochero Cifuentes, Aleksandar Aleksandrov, Serhat Atay, P. Van Hove, Alice Cocoros, G. Zevi Della Porta, Andreas Kornmayer, Bernard Ille, Florian Zenoni, Fatma Boran, Teimuraz Lomtadze, Claudio Caputo, J. Lykken, Pasquale Musella, Ali Mohammadi, Dinko Ferencek, G. P. Van Onsem, Zaixing Mao, O. Gonzalez Lopez, Alexander Schmidt, David Sheffield, Gabriella Pugliese, Suneel Dutt, John Strologas, J. Fernandez Menendez, Federico Ambrogi, Matthias Endres, D. Romero Abad, Marcos Cerrada, Laurent Thomas, Mark Derdzinski, Tai Sakuma, Hamed Bakhshiansohi, Kevin Deroover, Anterpreet Kaur, Alexey Volkov, I. Van Parijs, Jason Gran, Stephan Linn, Yu S. S., Marguerite Tonjes, Charles Maguire, J. R. González Fernández, Stephen Mrenna, Denys Lontkovskyi, Giovanni Franzoni, Evrim Ersin Kangal, Ashok Kumar, Krishna Thapa, M. Miñano Moya, Olena Karacheban, David Mark Raymond, Olivier Bondu, E. O. Olaiya, Esteban Curras, Christophe Delaere, Andrea Bocci, Roberto Dell'Orso, Pirmin Berger, Tommaso Dorigo, J. W. Gary, Sandra Malvezzi, Sergey Troshin, Pietro Faccioli, Kevin Lannon, Adrian Perieanu, G. Della Ricca, David J. Smith, Vyacheslav Valuev, Andris Skuja, Sébastien Brochet, Victor Murzin, Q. Li, Miaoyuan Liu, Jose Monroy, Alex Kamenev, Victor Kim, Luigi Benussi, A. Khan, Yutaro Iiyama, Mehmet Kaya, Intae Yu, David D'Enterria, G. Bagliesi, Yeonju Go, Nikolay Terentyev, Christophe Ochando, Marc Weinberg, Marco Zanetti, U. Bhawandeep, E. Belchior Batista Das Chagas, Tutanon Sinthuprasith, Anne Dabrowski, Tulika Bose, Mark Olschewski, Katja Klein, Andrei Gritsan, Willem Verbeke, Armando Lanaro, Guenakh Mitselmakher, Hamit Mermerkaya, D. H. Kim, Alberto Zucchetta, V. Petrov, Daniel Bloch, Tae Jeong Kim, Tariq Aziz, Dave M Newbold, Helio Nogima, Gouranga Kole, Stefan Gundacker, A. Starodumov, Ravi Janjam, Siddharth Narayanan, Anton Karneyeu, Leonard Apanasevich, M. Vander Donckt, Shao Min Tan, W. H. Smith, Ivan Reid, Anastasia Grebenyuk, G. Dissertori, Jason Kamin, Alexandre Zabi, Marko Dragicevic, Francesco Santanastasio, Stoyan Stoynev, A. Sanchez-Hernandez, Tongguang Cheng, Ijaz Ahmed, Elif Asli Yetkin, Konstantin Androsov, Dmitry Hits, Jorma Tuominiemi, R. F. Harr, Vladimir Rekovic, Vivek Sharma, Adrien Caudron, Sergo Jindariani, J. Schwandt, Alberto Orso Maria Iorio, Ivica Puljak, Hans Reithler, Felice Pantaleo, Chanwook Hwang, Ben Bylsma, R. Lopes De Sá, Roberto Tenchini, Michael Murray, Rachel Yohay, J. K. Lim, F. Simonetto, Mário Costa, Sergio P Ratti, Jakob Salfeld-Nebgen, Kenichi Hatakeyama, Frank Chlebana, Kuntal Mondal, Giovanni Organtini, Anna Woodard, Petr Levchenko, Kunal Kothekar, Paolo Spagnolo, P. Gras, Stefan Michael Heindl, W. Ji, Giuseppe Fasanella, Sung Keun Park, Jordan Damgov, Nikolai Golubev, Lindsey Gray, D. Di Croce, Peter Hansen, Kisung Lee, Wuming Luo, I. K. Furic, Alberto Belloni, Jay Mathew Lawhorn, Claude Amsler, Brent Yates, Piet Verwilligen, Ivan Glushkov, Katarzyna Romanowska-Rybinska, P. Rebello Teles, Amandeep Kaur Kalsi, Leonard Spiegel, Evgueni Vlasov, Giuseppe Benedetto Cerati, Stavros Mallios, Johannes Wittmann, James D. Olsen, Attilio Santocchia, N. V. Krasnikov, M. G. Albrow, Jeson Jacob, Jean Fay, Meng Xiao, Abideh Jafari, Anna Elliott-Peisert, S. Tkaczyk, Vuko Brigljevic, Nathan Mirman, Lucia Silvestris, David Taylor, B. Jayatilaka, Aran Garcia-Bellido, Sho Maruyama, Debarati Roy, K. Hurtado Anampa, Iasonas Topsis-Giotis, Franco Ligabue, A. B. Meyer, Burak Bilki, Nicolò Trevisani, Jochen Schieck, Nazar Bartosik, Gianluca Cerminara, Niladribihari Sahoo, Apichart Hortiangtham, Dezso Horvath, Lorenzo Russo, Y. C. Yang, Imad Baptiste Laktineh, Lucas Taylor, Matthew Citron, G. De Lentdecker, Lin Wang, Shalhout Shalhout, Y. Choi, Laurent Favart, Brandon Allen, Caleb Smith, A. 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Mao, Chiara Mariotti, Marco Monteno, Maria Spiropulu, D. M. Strom, Matthew Herndon, Thomas James, Elsayed Salama, Sevgi Tekten, Jovan Milosevic, Darren Puigh, Vitaliano Ciulli, Apostolos Panagiotou, Benjamin Kilminster, Aniello Spiezia, Christopher West, Zhoudunming Tu, Isabel Ojalvo, Youn Roh, Barry Blumenfeld, Alessio Boletti, Jie Zhang, Didier Contardo, Y. Chen, Francesca Romana Cavallo, Viktor Savrin, Mitchell Wayne, Karol Bunkowski, Rostyslav Shevchenko, S. Paktinat Mehdiabadi, Aruna Nayak, Michael Plagge, Giorgio Maggi, Sadia Khalil, C. Fernandez Bedoya, Gervasio Gomez, A. Delgado Peris, Stefan Grünendahl, Daniel Salerno, Philip Harris, Noemi Beni, Rohan Bhandari, Vinay Hegde, David Zou, Andrey Korytov, K. S. Lee, M. Della Negra, Maria Isabel Josa, P. Chang, Eduardo De Moraes Gregores, M. Tadel, Eva Halkiadakis, Frank Glege, Ashfaq Ahmad, Iurii Antropov, Deborah Duchardt, Andrea Perrotta, Jan Krolikowski, Luiz Mundim, C.-E. 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Suarez Gonzalez, Samuel Bein, Daniel Spitzbart, Roberto Rossin, Troy Mulholland, Yu G. B., James Castle, Seungkyu Ha, F. L. Fabbri, Daniele Fasanella, Alexander Ershov, D. Green, A. Gueth, Ana Ovcharova, Anna Julia Zsigmond, Andrea Venturi, M. Khakzad, Rino Castaldi, Mariarosaria D'Alfonso, Mario Galanti, Zoltan Szillasi, F. Rezaei Hosseinabadi, Andrey Uzunian, Christopher Palmer, Annika Vanhoefer, Alice Bean, Balazs Ujvari, Aaron Levine, Shervin Nourbakhsh, S. Belforte, Nabarun Dev, L. F. Chaparro Sierra, A. Bermúdez Martínez, R. Vidal, Maria Elena Pol, Oliver Pooth, Jan Steggemann, Andrés Cabrera, J. G. Branson, Barbara Clerbaux, Cristina Tuve, R. G. Kellogg, Borislav Pavlov, Csaba Hajdu, Emyr Clement, Mario Masciovecchio, Huilin Qu, Ari Lee, James Letts, Vipin Bhatnagar, T. Liu, Min-Hye Kim, Raffaella Radogna, Yang Wang, Ece Aşılar, K. F. Chen, Lei Feng, L. Malgeri, Kamuran Dilsiz, Steven Wasserbaech, Eleni Ntomari, Seema Bahinipati, Paolo Rumerio, Lorenzo Uplegger, Jan Hoss, Patrick Jarry, Christian Autermann, C. Woehrmann, Can You, Kenneth Bloom, Thomas Perry, M. De Mattia, G. Quast, Hannsjoerg Artur Weber, Gordon H. Hanson, Geonmo Ryu, John Stupak, Alexander Ledovskoy, Vincent J Smith, J. M. Grados Luyando, Jian-Guo Bian, Andrey Pozdnyakov, A. Quintario Olmeda, R. D. Field, Alexis Pompili, Louie Corpe, and Stephen Wimpenny
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Large Hadron Collider, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Hadron, Supersymmetry, Collision, 01 natural sciences, Charm quark, Pair production, 0103 physical sciences, Neutralino, High Energy Physics::Experiment, Neutrino, Nuclear Experiment, 010306 general physics
Abstract: Results are presented from a search for the pair production of third-generation squarks in proton–proton collision events with two-body decays to bottom or charm quarks and a neutralino, which produces a significant imbalance in the transverse momentum. The search is performed using a sample of proton–proton collision data at s=13TeV recorded by the CMS experiment at the LHC, corresponding to an integrated luminosity of 35.9 fb−1. No statistically significant excess of events is observed beyond the expected contribution from standard model processes. Exclusion limits are set in the context of simplified models of bottom or top squark pair production. Models with bottom squark masses up to 1220GeV are excluded at 95% confidence level for light neutralinos, and models with top squark masses of 510GeV are excluded assuming that the mass splitting between the top squark and the neutralino is small.
Published: 2018

34. Coherent J/ψ photoproduction in ultra-peripheral PbPb collisions at sNN=2.76TeV with the CMS experiment

Author: Brian Pollack, C-E Wulz, Ashutosh Bhardwaj, S. Tkaczyk, Kelly Beernaert, David Stuart, Alice Mignerey, Evgenii Tarkovskii, Chayanit Asawatangtrakuldee, Yetkin Yilmaz, Peter Raics, Peicho Petkov, Vladimir Epshteyn, Leonardo Cristella, Paul Geffert, M. Correa Martins, Achille Petrilli, Chun-Hua Jiang, David Sperka, Gaelle Boudoul, Wolfgang Waltenberger, Alexis Kalogeropoulos, Florian Zenoni, Kristian Harder, John Strologas, J. Fernandez Menendez, Sushil Chauhan, Kajari Mazumdar, Nickolas Mccoll, Lovedeep Kaur Saini, Charles Maguire, Mircho Rodozov, Marcus Hohlmann, Hannes Neugebauer, Sharad Malik, B. Roland, Carlos Florez, Andrés G Delannoy, Christopher Hill, T. Müller, Jacopo Bernardini, Tobias Pook, Jay Hauser, A. Vilela Pereira, Pedro Silva, Y. W. Chang, J. Mejia Guisao, Regina Demina, Maria Roberta Monge, Teresa Rodrigo, Denis Favart, H. Van Haevermaet, Clemens Wöhrmann, Michal Simon, A. Awad, Soon-Kwon Nam, Amitabh Lath, Angela Mehta, Michael Brodski, Roberto Castello, Sam Harper, Matthias Schröder, Jennifer S. Haas, Sourabh Dube, B. A. Barnett, C. Martinez Rivero, Giorgio Apollinari, Ulf Behrens, Charles Mueller, Shuichi Kunori, Yeonju Go, Nikolay Terentyev, Christophe Ochando, Joram Berger, Elizabeth Sexton-Kennedy, Mihee Jo, Matthias Wolf, Tom Cornelis, Shivali Malhotra, Francesco Santanastasio, Stoyan Stoynev, A. Sanchez-Hernandez, Teruki Kamon, Srecko Morovic, Bruno Casal, Paolo Ronchese, Shang Liu, Badder Marzocchi, Sanjay Kumar Swain, Marc M Baarmand, Matthew Walker, P. Bloch, Josh Kaisen, Simon Fink, Sergo Jindariani, J. Schwandt, Anna Kropivnitskaya, Stefan Wayand, Scott Wilbur, D. Cutts, Michael Northup, Yi Chen, Michael Benjamin Andrews, Simone Paoletti, Rebecca Lane, Teresa Lenz, Daniele Trocino, A. Di Francesco, Ulrich Heintz, M. Kovac, Adam Elwood, Enrique Calvo, Andreas Künsken, Laurent Thomas, Mark Derdzinski, Tapas Sarangi, A. Stahl, David Sabes, Arun Kumar, Matti J Kortelainen, Laurent Mirabito, C. Beirão Da Cruz E Silva, Steven Lowette, Sami Lehti, Ali Fahim, Joseph Goodell, Adish Vartak, Stephen Sanders, David Petyt, Dan Knowlton, W. Van Doninck, Xin Shi, Ennio Monteil, Aldo Penzo, Natalie Heracleous, Manqi Ruan, John J. Leonard, John Bradmiller-Feld, John Hakala, M. Vazquez Acosta, Raffaele Tito D'Agnolo, Erhan Gülmez, Kaori Maeshima, Brian L Winer, Donato Creanza, Marc Dobson, Donald Belknap, Heiner Tholen, Winston Ko, I. De Bruyn, Reza Goldouzian, Andrea Schizzi, Mohd Nizam Yusli, Victor Murzin, Martin Erdmann, James Faulkner, A. Escalante Del Valle, Joosep Pata, Hans Rykaczewski, W. L. Aldá, Igor Golutvin, Atanu Modak, Bastian Kargoll, Peter Elmer, F. M. Stober, Jiawei Fan, Patricia McBride, P. de Barbaro, Daniel Teyssier, John Yelton, T. Lenzi, Krzysztof Doroba, Renato Potenza, A. 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Salva, Stephanie Beauceron, Joshua Kunkle, Ulrich Husemann, Valentina Sola, Gregory Habib Hammad, Tengizi Toriashvili, S. Bhattacharya, Rizki Syarif, Ia Iashvili, Roberto Guida, Fabio Colombo, Jean-Roch Vlimant, Brajesh C Choudhary, Paul David Luckey, Marco Trovato, Sébastien Viret, G. P. Van Onsem, Zaixing Mao, O. Gonzalez Lopez, A. Van Spilbeeck, Sara Alderweireldt, Olena Karacheban, Andreas Kornmayer, Luigi Benussi, A. Khan, Gouranga Kole, Stefan Gundacker, A. Starodumov, Ravi Janjam, Siddharth Narayanan, Anton Karneyeu, Leonard Apanasevich, M. Vander Donckt, Alexey Svyatkovskiy, Jochen Schieck, Vincenzo Chiochia, Charalambos Nicolaou, Niki Saoulidou, Sercan Sen, D. P. Stickland, Y. H. Chang, Zhenyu Chen, Geoffrey Smith, C. Neu, Roberto Sacchi, Natascha Hörmann, Tejinder Virdee, Nicolò Tosi, M. Jones, Camilla Galloni, Seth Conrad Zenz, I. Heredia-De La Cruz, Andrew Godshalk, Vincenzo Daponte, Federica Primavera, M. Vidal Marono, Daniele Marconi, S. De Visscher, W. Bertl, Julia Thom, Finn Rebassoo, Volker Blobel, Joshua Hardenbrook, Neeti Parashar, Klaus Rabbertz, Orduna Jesus, Igor Lokhtin, Myriam Schönenberger, Zachary Lesko, Paul Turner, J. Seixas, Alexandra Junkes, Suyong Choi, Etiennette Auffray, Nil Valls, Navid Rad, Alexandre Sakharov, Susan Gascon, T. Yetkin, A. Yagil, Sinan Sagir, Marta Felcini, Gunther Roland, Yue Shi Lai, Ie. Korol, C. La Licata, Lea Caminada, Nikitas Loukas, Matthias Geisler, Rafael Marco, Sanmay Ganguly, Simon Regnard, Mani Tripathi, Rachel Bartek, Marco Peruzzi, L. Lloret Iglesias, Owen Rosser Long, Warren Clarida, Leonid Levchuk, Luca Scodellaro, Dana Z. Anderson, Cesare Calabria, Nicola Amapane, S. Schael, Maria Cepeda, Jorgen D'Hondt, Davide Piccolo, Bahareh Roozbahani, Matteo Sani, Andreas Nowack, Nadeesha Wickramage, Anna Zanetti, Eleni Petrakou, Q. Ingram, Paul Avery, Salavat Abdullin, Lisa Benato, Quentin Python, Randy Ruchti, Joe Incandela, Luca Cadamuro, Virginia Azzolini, Andrew Ackert, John F. Thompson, Koushik Mandal, S. Cihangir, Andrii Gizhko, Manfred Paulini, Pierluigi Bortignon, Veikko Karimäki, Alberto Benvenuti, Maria Florencia Canelli, Fabrizio Ferro, Thomas Ferbel, Dan Green, Allison Reinsvold, Vasken Hagopian, G. M. Dallavalle, Zeynep Demiragli, Yalcin Guler, Lars Sonnenschein, Marta Ruspa, Stepan Obraztsov, Anshul Kapoor, S. D. Worm, Roger Wolf, Marina Chadeeva, Jeremy Andrea, Gabriella Pugliese, I. Van Parijs, Jason Gran, Joseph Heideman, Hong Ni, W. T. Ford, Pierluigi Zotto, S. Lee, Hwi Dong Yoo, Kevin Lannon, G. Della Ricca, Guenakh Mitselmakher, Robert Bainbridge, Jordan Damgov, Gobinda Majumder, Peter Hansen, Kisung Lee, Jane Nachtman, R. Gonzalez Suarez, Sergio F Novaes, I. K. Furic, Claude Amsler, Brent Yates, Morgan Lethuillier, Charles Dietz, Yasar Onel, Laurent Favart, Amedeo Staiano, Ignacio Redondo, Benjamin Stieger, Cristian Pena, Thomas Reis, Martin Lipinski, Kristin Goebel, Frank Würthwein, Manas Maity, Alexi Mestvirishvili, Ulrich Goerlach, Massimo Casarsa, Steve Nahn, Marco Meschini, Paolo Capiluppi, James Rohlf, Carlos Avila, Sergei Bitioukov, John L Wood, Jan Veverka, Yurii Maravin, Vladimir Gavrilov, Aleko Khukhunaishvili, Stefano Marcellini, Sonaina Undleeb, Markus Friedl, Ricardo Eusebi, R. M. Brown, Hannes Jung, Alexander Zhokin, Martijn Mulders, A. Rose, Darin Baumgartel, Kamal Lamichhane, Mingming Yang, Martino Margoni, Jochen Ott, Y. F. Liu, Michael Krohn, Jeremie Alexandre Merlin, Piotr Zalewski, Xinmei Niu, Vitaly Smirnov, Nayana Majumdar, Dragos Velicanu, Qamar Hassan, and Nuno Leonardo
Subjects: Physics, Quantum chromodynamics, Nuclear and High Energy Physics, Particle physics, Meson, 010308 nuclear & particles physics, Nuclear Theory, Bremsstrahlung, HERA, 01 natural sciences, 7. Clean energy, Gluon, Nuclear physics, 0103 physical sciences, High Energy Physics::Experiment, Neutron, Rapidity, Nuclear Experiment, 010306 general physics, Crystal Ball
Abstract: The cross section for coherent J/psi photoproduction accompanied by at least one neutron on one side of the interaction point and no neutron activity on the other side, X[n]0[n], is measured with the CMS experiment in ultra-peripheral PbPb collisions at sqrt(s[NN]) = 2.76 TeV. The analysis is based on a data sample corresponding to an integrated luminosity of 159 inverse microbarns, collected during the 2011 PbPb run. The J/psi mesons are reconstructed in the dimuon decay channel, while neutrons are detected using zero degree calorimeters. The measured cross section is dsigma[coh, X[n]0[n]] / dy(J/psi) = 0.36 +/- 0.04 (stat) +/- 0.04 (syst) mb in the rapidity interval 1.8 < abs(y) < 2.3. Using a model for the relative rate of coherent photoproduction processes, this X[z, n, z] measurement gives a total coherent photoproduction cross section of dsigma[coh] / dy(J/psi) = 1.82 +/- 0.22 (stat) +/- 0.20 (syst) +/- 0.19 (theo) mb. The data strongly disfavour the impulse approximation model prediction, indicating that nuclear effects are needed to describe coherent J/psi photoproduction in gamma + Pb interactions. The data are found to be consistent with the leading twist approximation, which includes nuclear gluon shadowing.
Published: 2017

35. Search for anomalous couplings in boosted WW/WZ→ℓνqq‾ production in proton–proton collisions at s=8 TeV

Author: André Holzner, Tiziano Rovelli, Alexis Pompili, Joschka Lingemann, Michal Bluj, Giuseppe Lanza, Emmanuel Olaiya, Alexander Schmidt, Vytautas Dudenas, Andrey Marinov, Louie Corpe, Stephen Wimpenny, Henning Flacher, Nadir Daci, David Sheffield, Amitabh Lath, Simon Kudella, Francesca Cenna, Tomasz Frueboes, Alberto Ruiz-Jimeno, C. Martinez Rivero, Nikolaos Manthos, Christian Laner, Martin Grunewald, J. Piedra Gomez, Gobinda Majumder, Mohsen Khakzad, Suneel Dutt, Roberto Dell'Orso, J. W. Gary, Giorgio Apollinari, Ulf Behrens, Federico Preiato, Charles Mueller, Kunal Kothekar, Stefano Ragazzi, Jane Nachtman, S. Fonseca De Souza, Sergio F Novaes, Teruki Kamon, Dmitry Elumakhov, Bruno Casal, Sergey Troshin, L. Wendland, Oleg Prokofyev, Wolfram Erdmann, Nicolo Cartiglia, Zuhal Seyma Demiroglu, Robert Cousins, Mara Senghi Soares, Serguei Ganjour, David D'Enterria, G. Dolinska, A. Di Francesco, Juan Garcia-Ferrero, Ulrich Heintz, Silvia Taroni, Arun Kumar, Morgan Lethuillier, Pushpalatha C Bhat, Didar Dobur, S. Goy Lopez, Giuseppe Barbagli, Simone Pigazzini, Yasar Onel, Helena Bialkowska, Erhan Gülmez, Kaori Maeshima, Aurelijus Rinkevicius, Martin Erdmann, Andrey Popov, Lawrence Sulak, Ahmad Borzou, Nicole Ruckstuhl, Austin Ball, P. Verdier, Guido Tonelli, Zeljko Antunovic, Claudia-Elisabeth Wulz, Christoph Paus, A. Grohsjean, Helio Nogima, Wolfgang Waltenberger, Jonatan Piedra Gomez, Piergiulio Lenzi, Arthur Moraes, Vladimir Blinov, Nathaniel Odell, Alexander Dierlamm, Patricia McBride, Krzysztof Doroba, Jorge Luis Rodriguez, Dylan Rankin, Andrew Brinkerhoff, E. Eskut, K. Krajczar, David Curry, Martin Flechl, K. Hurtado Anampa, Jian Wang, David Petyt, W. Van Doninck, Xin Shi, Hans Rykaczewski, Hui Li, Salvatore My, James Keaveney, Darien Wood, Seth Cooper, Michal Szleper, Philippe Gras, Roberto Chierici, Chia-Ming Kuo, Jyothsna Rani Komaragiri, James Dolen, Freya Blekman, Ilse Krätschmer, David Michael Morse, G. Hamel de Monchenault, Aditee Rane, Kai-Feng Chen, Chiara Mariotti, Thomas Ferguson, Thierry Maerschalk, Isabell-Alissandra Melzer-Pellmann, Nicholas John Hadley, Mark Turner, Jehad Mousa, P. Goldenzweig, Ettore Focardi, Vallary Bhopatkar, John Rander, Josef Strauss, Ulascan Sarica, Maria Toms, John Michael Marraffino, E. De La Cruz-Burelo, J. Ellison, Sa. Jain, Kenneth Call, Alberto Orso Maria Iorio, Felice Pantaleo, Chanwook Hwang, Ignacio Redondo, Benjamin Stieger, Hyun-Chul Kim, Cesar Augusto Bernardes, Jack Wright, Aniello Spiezia, Jose Flix, Semra Turkcapar, Yurii Maravin, Joonas Talvitie, Alexandre Zabi, Vladimir Rekovic, Linda Finco, Iasonas Topsis-Giotis, Alexander Toropin, S. M. A. Ghiasi Shirazi, Dominic Smith, Y. H. Chang, Alessandro Degano, Constantin Heidegger, Deniz Poyraz, Alexey Volkov, Candan Dozen, Karl Matthew Ecklund, C. Diez Pardos, Michael Wayne Arenton, Kirti Ranjan, Keith Rose, Mingshui Chen, Nikita Beliy, Sean Kalafut, Maral Alyari, Matti J Kortelainen, S. Abu Zeid, Giuseppe Bagliesi, J. D. Ruiz Alvarez, Milos Dordevic, Dooyeon Gyun, Alessio Boletti, Jie Zhang, Vladimir Gavrilov, Jordan Nash, Giuseppe Fasanella, Sung Keun Park, Virgil E Barnes, Fanbo Meng, Caroline Collard, Georgios Anagnostou, Melody A. Swartz, Maxwell Chertok, Esraa El-Khateeb, Danek Kotlinski, Simone Gelli, Niladribihari Sahoo, Apichart Hortiangtham, Dezso Horvath, Denis Gelé, Chang-Seong Moon, Mauro Emanuele Dinardo, Sven Dildick, Nhan Viet Tran, Christof Roland, Marino Missiroli, C. 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Sanchez Cruz, Mauro Menichelli, Luca Perniè, Roland Horisberger, Yuan Chao, Georgios Mavromanolakis, Michele Arneodo, Plamen Iaydjiev, Christopher Anelli, Nikitas Loukas, M. Rossini, Mani Tripathi, Rachel Bartek, Marco Peruzzi, Brieuc Francois, L. Lloret Iglesias, Owen Rosser Long, Paul Edmund Karchin, G. F. Chen, Akram Khan, A. Pérez-Calero Yzquierdo, Nicolas Chanon, Helena Malbouisson, Alex J. Barker, Camelia Mironov, Georg Sieber, Warren Clarida, Cesare Calabria, Nicola Amapane, Matteo Sani, Ilknur Hos, J. N. Butler, Genius Walia, Paolo Lariccia, D. A. Belknap, Stefan Piperov, Florian Zenoni, J. Fernandez Menendez, Charles Maguire, Theodoros Geralis, J. R. González Fernández, Andrea Rizzi, Andreas Nowack, J. F. Low, Andrew Ackert, Elif Asli Yetkin, Koushik Mandal, Paraskevas Sphicas, Clemens Wöhrmann, Yeonju Go, V. Golovtsov, Christophe Ochando, Francesco Santanastasio, Stoyan Stoynev, A. Sanchez-Hernandez, Tongguang Cheng, Sergo Jindariani, A. G. Stahl Leiton, John Bradmiller-Feld, Rino Castaldi, Alexander Bylinkin, Alberto Benvenuti, Maria Agnese Ciocci, Dave Pellett, Marko Kovac, Maria Florencia Canelli, Fabrizio Ferro, Thomas Ferbel, Dan Green, Daniel Teyssier, T. Lenzi, Victor Perelygin, Alessandra Fanfani, Andrew Askew, Gurpreet Singh, Styliani Orfanelli, M. Olmedo Negrete, Marta Ruspa, Stepan Obraztsov, Evaldas Juska, Till Arndt, Shao Min Tan, Roberto Sacchi, Tejinder Virdee, Nicolò Tosi, Camilla Galloni, Seth Conrad Zenz, I. Heredia-De La Cruz, Andrew Godshalk, Vincenzo Daponte, M. Vidal Marono, Daniele Marconi, S. De Visscher, Julia Thom, Finn Rebassoo, Volker Blobel, Joshua Hardenbrook, Lucia Silvestris, Neeti Parashar, Klaus Rabbertz, Sebastiano Albergo, Igor Lokhtin, Zachary Lesko, Robert M Brown, Atanu Modak, Bastian Kargoll, Marco Cipriani, Peter Elmer, Stephan Albert Wiederkehr, F. M. Stober, Mikhail Dubinin, Wei Li, Wei Xie, Rainer Wallny, Ivan Amos Cali, A. 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Futyan, Aran Garcia-Bellido, Sho Maruyama, Debarati Roy, Franco Ligabue, Kenneth Long, Andrea Carlo Marini, Alexander Tapper, Vyacheslav Krutelyov, Deborah Pinna, Caterina Vernieri, A. Lopez Virto, A. Baden, Gino Bolla, M. Barrio Luna, P. Martinez Ruiz del Arbol, Rylan Conway, J. F. de Trocóniz, Matthias Ulrich Mozer, A. Morelos Pineda, Johannes Brandstetter, S. B. Oh, Alexander Malakhov, Efe Yazgan, Günter Flügge, Qiao Xu, M. Naimuddin, Tyler Ruggles, Robert Clare, Patrizia Azzi, Thomas Hebbeker, Paul Lecoq, A. De Roeck, A. David, Ksenia Shchelina, Albert M. Sirunyan, A. De Wit, Frans Meijers, Edward Scott, Stefano Colafranceschi, C. Scharf, Siarhei Shulha, Paolo Gunnellini, Batool Safarzadeh, Juliet Ritchie Patterson, Joao Varela, Leander Litov, Jean-Pierre Merlo, Rocky Bala Garg, Joanne Cole, Luigi Fiore, Lucia Perrini, Patrick Connor, Roberval Walsh, Giovanna Selvaggi, Daniel Abercrombie, Gagan Bihari Mohanty, Gabor Istvan Veres, Alexandre Mertens, Sarah Catherine Eno, Jan-Frederik Schulte, Minkyoo Choi, Hugues Brun, Pieter Everaerts, Titas Roy, Alexx Perloff, Roman Ryutin, Federica Primavera, Roberto Carlin, Pierre Depasse, Vyacheslav Klyukhin, M. Van De Klundert, S. Dogra, Sören Erdweg, J. C. Sanabria, Chris Lucas, R.-J. Wang, Mustafa Numan Bakirci, Dustin Stolp, Lorenzo Viliani, Kurt Jung, Kristian Harder, Vladimir Petrov, Thomas N. Williams, Josh Kaisen, Stefan Wayand, Simone Paoletti, Rebecca Lane, Suchandra Dutta, Anne-Marie Magnan, Wagner Carvalho, Terhi Jarvinen, Greg Landsberg, Cécile Caillol, Manjit Kaur, Fan Yang, J. Rodrigues Antunes, Francesco Fiori, Philippe Busson, Pedrame Bargassa, Nick Amin, Kira Burt, Mehar Ali Shah, Thomas Peiffer, D. Shtol, Ketino Kaadze, C. Hartl, and Christian Contreras-Campana
Subjects: Physics, Nuclear and High Energy Physics, Gauge boson, Particle physics, Luminosity (scattering theory), Large Hadron Collider, Proton, 010308 nuclear & particles physics, Physics beyond the Standard Model, High Energy Physics::Phenomenology, 01 natural sciences, Standard Model, Nuclear physics, 0103 physical sciences, Effective field theory, High Energy Physics::Experiment, 010306 general physics, Compact Muon Solenoid
Abstract: This Letter presents a search for new physics manifested as anomalous triple gauge boson couplings in WW and WZ diboson production in proton–proton collisions. The search is performed using events containing a W boson that decays leptonically and a W or Z boson whose decay products are merged into a single reconstructed jet. The data, collected at s=8 TeV with the CMS detector at the LHC, correspond to an integrated luminosity of 19 fb−1 . No evidence for anomalous triple gauge couplings is found and the following 95% confidence level limits are set on their values: λ ( [−0.011,0.011] ), Δκγ ( [−0.044,0.063] ), and Δg1Z ( [−0.0087,0.024] ). These limits are also translated into their effective field theory equivalents: cWWW/Λ2 ( [−2.7,2.7] TeV−2 ), cB/Λ2 ( [−14,17] TeV−2 ), and cW/Λ2 ( [−2.0,5.7] TeV−2 ).
Published: 2017

36. Search for narrow resonances in dilepton mass spectra in proton–proton collisions at s=13 TeV and combination with 8 TeV data

Author: Rylan Conway, J. F. de Trocóniz, Matthias Ulrich Mozer, Massimiliano Chiorboli, A. Morelos Pineda, Johannes Brandstetter, S. B. Oh, Alexander Malakhov, Efe Yazgan, Günter Flügge, Qiao Xu, M. Naimuddin, Tyler Ruggles, Robert Clare, Patrizia Azzi, Thomas Hebbeker, Paul Lecoq, A. De Roeck, Ian Michael Nugent, A. J. Campbell, A. David, Albert M. Sirunyan, M. Weber, Carlotta Favaro, A. De Wit, Frans Meijers, Kristian Harder, P. Bloch, Josh Kaisen, Stefan Wayand, Scott Wilbur, D. Cutts, Michael Benjamin Andrews, Simone Paoletti, Rebecca Lane, Suchandra Dutta, Anne-Marie Magnan, Wagner Carvalho, S. C. Kao, Severiano Carpinteyro, Florian Zenoni, Greg Landsberg, Cécile Caillol, Manjit Kaur, Anna Colaleo, J. Rodrigues Antunes, Francesco Fiori, M. Fernandez, S. Somalwar, Pedrame Bargassa, Nikolay Voytishin, Kira Burt, Thomas Peiffer, Pushpalatha C Bhat, Joseph Goodell, Stephen Sanders, Pawandeep Jandir, Stefano Colafranceschi, C. Scharf, Siarhei Shulha, Paolo Gunnellini, Juliet Ritchie Patterson, Ibrahim Soner Zorbakir, Benjamin Michlin, Andreas Hinzmann, Mircho Rodozov, B. Roland, James Faulkner, A. Escalante Del Valle, Joosep Pata, Colin Bernet, Ugur Kiminsu, Vardan Khachatryan, A. Savoy-Navarro, Andrey Popov, Andrzej Zuranski, K. Krajczar, L. J. Gutay, Troy Mulholland, J. Fernandez Menendez, Charles Maguire, J. R. González Fernández, Amr Radi, Alexis Pompili, Louie Corpe, Stephen Wimpenny, Henning Flacher, Anita Topkar, Agnieszka Zagozdzinska, Elvire Bouvier, Giuseppe Iaselli, Marcin Konecki, Artur Lobanov, Nathaniel Pastika, Felix Bachmair, Jose Chinellato, Richard Cavanaugh, Maxim Konyushikhin, Evaldas Juska, C. Neu, Joao Varela, Leander Litov, Joshy George, Jean-Pierre Merlo, Rocky Bala Garg, Joanne Cole, Myung-kwan Ryu, Lucia Perrini, Patrick Connor, Giovanna Selvaggi, Daniel Abercrombie, Gabor Istvan Veres, Alexandre Mertens, P. Van Hove, Sarah Catherine Eno, Jan-Frederik Schulte, Hugues Brun, Pieter Everaerts, J. Y. Han, Titas Roy, Alexx Perloff, Roberto Carlin, J. F. Tsai, Pierre Depasse, Vyacheslav Klyukhin, M. Van De Klundert, Sören Erdweg, Chris Lucas, Richard B. Lipton, Georgi Sultanov, Mustafa Numan Bakirci, Lorenzo Viliani, Kurt Jung, Dimitri Bourilkov, Vassili Kachanov, S. W. Cho, Andrew Whitbeck, Viktor Veszpremi, Abdulla Abdulsalam, Michael Seidel, I. Gonzalez Caballero, Shabnam Jabeen, Andrés G Delannoy, Christopher Hill, Adam Elwood, David Curry, V. Andreev, Joonas Talvitie, Martti Raidal, Emmanuel Contreras-Campana, Pamela Klabbers, Ian Anderson, Burin Asavapibhop, Aram Avetisyan, Vladimir Cherepanov, Giuseppe Fasanella, Sung Keun Park, Junquan Tao, Tiziano Rovelli, Giuseppe Lanza, Andrey Marinov, Maryam Zeinali, Patrick Jarry, Benjamin Charles Radburn-Smith, James Castle, Seungkyu Ha, Georgia Karapostoli, Clemens Wöhrmann, Yeonju Go, Pàl Hidas, Roberto Sacchi, Nikolaos Manthos, Christian Laner, Martin Grunewald, Navid Rad, J. Piedra Gomez, Atanu Modak, Andreas Künsken, Evan Wolfe, Kevin Stenson, C. Mora Herrera, Ioannis Evangelou, Stephanie Baffioni, Ivan Pozdnyakov, Ruchi Chudasama, Guido Tonelli, Hasan Ogul, Daniel Duggan, Zeljko Antunovic, Kevin Mcdermott, Dmytro Kovalskyi, T. Weiler, Gyorgy Vesztergombi, Christoph Paus, Piergiulio Lenzi, Ali Harb, Frank Jm Geurts, Alexander Gude, Tai Sakuma, F. Mohamad Idris, R. Sharma, Alessandro Degano, Matthew Nguyen, J. 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Suárez Andrés, Zuhal Seyma Demiroglu, Valentina Dutta, Marco Esposito, Petra Merkel, Devdatta Majumder, Pelin Kurt, Jorge Chaves, Si Xie, Robert Stone, Daniel Troendle, Panja-Riina Luukka, J. A. Nash, M. Jones, Camilla Galloni, Seth Conrad Zenz, Simon Fink, Sergo Jindariani, J. Schwandt, Didar Dobur, S. Goy Lopez, Nicholas Wardle, Loic Quertenmont, Aram Apyan, Marco Cipriani, Peter Elmer, F. M. Stober, I. Heredia-De La Cruz, Arka Santra, Roberto Salerno, Tao Huang, Nicole Ruckstuhl, Jennifer Ngadiuba, Yutaro Iiyama, Thomas Schoerner-Sadenius, Mara Senghi Soares, Serguei Ganjour, Nicola Bacchetta, Attila Racz, Roberta Arcidiacono, Christian Schnaible, Jonathan Fulcher, Olga Kodolova, Anatoli Pashenkov, Avto Kharchilava, Mikhail Ignatenko, Jelena Luetic, Damir Lelas, Austin Ball, S. M. Spanier, James S. Wright, Silvia Taroni, Tapio Lampén, Elisabetta Gallo, Ilya Gorbunov, M. 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Martinez Ruiz del Arbol, Didier Contardo, Emanuela Barberis, Nicolo Magini, Michael Dittmar, R. Kunnawalkam Elayavalli, Steven Kaplan, J. A. Brochero Cifuentes, Aleksandar Aleksandrov, Frank Raupach, Jacob Linacre, Bernard Ille, Ali Mohammadi, Christian Hartl, Dinko Ferencek, Giovanni Franzoni, Evrim Ersin Kangal, Ashok Kumar, Krishna Thapa, M. Miñano Moya, E. Belchior Batista Das Chagas, Anne Dabrowski, Tulika Bose, Wuming Luo, P. Rebello Teles, Amandeep Kaur Kalsi, Leonard Spiegel, Francesco Romeo, Fabio Cossutti, Igor Katkov, Joachim Mnich, Robert Klanner, Paolo Giacomelli, Camille Beluffi, Andreas Mussgiller, Fotios Ptochos, Batool Safarzadeh, Maria Hempel, Riccardo Bellan, Michael Gardner, Darin Acosta, Youngkwon Jo, Kristian Allan Hahn, Suresh C Tonwar, Sylvie Braibant-Giacomelli, Jeffrey Roskes, Claudio Grandi, Guillaume Garcia, Sébastien Gadrat, Mayda Velasco, S. Fonseca De Souza, Louise Skinnari, Nural Akchurin, James Keaveney, Dipanwita Dutta, Alexei Safonov, Janos Erö, Ian Fisk, Constantin Heidegger, Julia Velkovska, Tobias Lapsien, Sudha Ahuja, Halil Saka, Pietro Govoni, Gianni Zumerle, Mark Foerster, Sunil Bansal, P. M. Ribeiro Cipriano, Pierre Lecomte, Stefano Lacaprara, Sheng Wang, Frank Jensen, Nicholas Smith, Jean-Charles Fontaine, Anton Dimitrov, Andrea Gozzelino, Werner Lustermann, Andromachi Tsirou, Tatiana Medvedeva, R. Placakyte, Maria Girone, Daniele Bonacorsi, Y. J. Lu, V. Sola, R. Di Maria, Hannes Mildner, Jay Dittmann, Pawan Kumar Netrakanti, Ricardo Lopez-Fernandez, Davide Cieri, Giovanni Polese, Alexander Toropin, Petar Adzic, Svenja Schumann, Rami Kamalieddin, Maria Margherita Obertino, Alajos Makovec, Christian Sander, Muhammad Gul, Engin Eren, P. Van Mulders, Subhadeep Banerjee, Michele Gallinaro, Giorgia Miniello, Peter Wittich, Valentin Sulimov, Francesco Fabozzi, Michal Olszewski, Christine O'Brien, Stefaan Tavernier, Diego Ciangottini, A. Baden, Gino Bolla, and M. Barrio Luna
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Large Hadron Collider, 010308 nuclear & particles physics, Branching fraction, Physics beyond the Standard Model, Coupling (probability), 7. Clean energy, 01 natural sciences, Extra dimensions, Randall–Sundrum model, 0103 physical sciences, High Energy Physics::Experiment, Invariant mass, Nuclear Experiment, 010306 general physics, Compact Muon Solenoid
Abstract: A search for narrow resonances in dielectron and dimuon invariant mass spectra has been performed using data obtained from proton–proton collisions at $\sqrt{s}=13$ TeV collected with the CMS detector. The integrated luminosity for the dielectron sample is 2.7 fb$^{-1}$ and for the dimuon sample 2.9 fb$^{-1}$. The sensitivity of the search is increased by combining these data with a previously analyzed set of data obtained at$\sqrt{s}=8$ TeV and corresponding to a luminosity of 20 fb$^{-1}$. No evidence for non-standard-model physics is found, either in the 13 TeV data set alone, or in the combined data set. Upper limits on the product of production cross section and branching fraction have also been calculated in a model-independent manner to enable interpretation in models predicting a narrow dielectron or dimuon resonance structure. Limits are set on the masses of hypothetical particles that could appear in new-physics scenarios. For the $Z'_{SSM}$ particle, which arises in the sequential standard model, and for the superstring inspired $Z'_\psi$ particle, 95% confidence level lower mass limits for the combined data sets and combined channels are found to be 3.37 and 2.82 TeV, respectively. The corresponding limits for the lightest Kaluza–Klein graviton arising in the Randall–Sundrum model of extra dimensions with coupling parameters 0.01 and 0.10 are 1.46 and 3.11 TeV, respectively. These results significantly exceed the limits based on the 8 TeV LHC data.
Published: 2017

37. Measurement of the ZZ production cross section and Z →ℓ+ℓ−ℓ′+ℓ′− branching fraction in pp collisions at s=13 TeV

Author: Ibrahim Soner Zorbakir, Benjamin Michlin, Alexandra Carvalho Antunes De Oliveira, Anita Topkar, Giuseppe Fasanella, Sung Keun Park, Bugra Bilin, Sudeshna Banerjee, Catherine Vander Velde, Elvire Bouvier, Giuseppe Iaselli, Georgi Sultanov, Natale Demaria, Alexis Pompili, Evan Wolfe, David Cutts, Gian Luca Pinna Angioni, Kevin Stenson, Achim Stahl, M. Mohammadi Najafabadi, Charles Harrington, Daniel Troendle, Panja-Riina Luukka, Louie Corpe, Stephen Wimpenny, Riccardo Paramatti, Andrea Giammanco, Betty Calpas, Roberto Salerno, Olga Kodolova, Ram Krishna Dewanjee, Bora Isildak, Rafael Lopes De Sá, Antony Adair, Kati Lassila-Perini, Naimuddin, Marco Esposito, Petra Merkel, Pelin Kurt, Alberto Escalante Del Valle, Po-Hsun Chen, Stefano Mersi, Troy Mulholland, Vladimir Andreev, Ramandeep Kumar, Aruna Nayak, Michael Plagge, Guido Tonelli, Henning Flacher, Pàl Hidas, Narumon Suwonjandee, Christopher Bruner, Nikolaos Manthos, Gervasio Gomez, Christian Laner, Martin Grunewald, Jorge Chaves, Si Xie, Robert Stone, Frank Meier, Nicolas Zaganidis, W. A. T. Wan Abdullah, Jamal Rorie, Andreas Künsken, Jason Gilmore, Laurent Thomas, Mark Derdzinski, Florian Zenoni, Victor Murzin, Ringaile Placakyte, Tutanon Sinthuprasith, Serguei Afanasiev, Marco Paganoni, Jacopo Bernardini, Tobias Pook, Jay Hauser, Andrei Starodumov, Isidro Gonzalez Caballero, Michael Brodski, Francesca Cavallari, Stefano Belforte, Massimo Casarsa, James Castle, Seungkyu Ha, Christian Barth, Daniele Fasanella, Roberto Castello, Federico Preiato, Oleg Prokofyev, Wolfram Erdmann, Nicolo Cartiglia, Gino Bolla, Zeljko Antunovic, Claudia-Elisabeth Wulz, Christoph Paus, Wolfgang Waltenberger, Archana Sharma, Sung Won Lee, Thomas Müller, Andrés G Delannoy, Christopher Hill, Elizabeth Sexton-Kennedy, Matthias Wolf, Paolo Ronchese, Badder Marzocchi, Sanjay Kumar Swain, Marc M Baarmand, Daniele Trocino, Silvia Maselli, Jennifer Poehlsen, Paul Kyberd, David Sabes, Ali Fahim, Charles Maguire, Theodoros Geralis, Mara Senghi Soares, Serguei Ganjour, Don Lincoln, Mukund Varma, Hafeez R Hoorani, Piergiulio Lenzi, Donald Belknap, Winston Ko, Reza Goldouzian, Andrea Schizzi, Mohd Nizam Yusli, Daniel Salerno, Kisoo Lee, Lalit Mohan Pant, Renato Potenza, Aaron Dominguez, Abdollah Mohammadi, Walter Luiz Aldá Júnior, Felicitas Pauss, Celso Martinez Rivero, Andrea Rizzi, Amr Radi, Austin Baty, Ricardo Magaña Villalba, Paolo Giacomelli, Valerio Calvelli, Guenter Eckerlin, Annik Olbrechts, Armen Tumasyan, Shin-Shan Yu, Nicholas Wardle, Arka Santra, Tao Huang, Saeid Paktinat Mehdiabadi, Wenxing Fang, Geoffrey Hall, William Mcbrayer, Andris Skuja, Sébastien Brochet, Sanjay Padhi, Mark Olschewski, Katja Klein, Bjoern Penning, Paula Eerola, Manoj Sharan, Isa Dumanoglu, Panagiotis Kokkas, Sam Daniel Mullin, Niels Dupont, Giacomo Sguazzoni, Alan Campbell, Sarah Malik, Edward Laird, Aurore Savoy-Navarro, Silvia Taroni, Luca Mastrolorenzo, Philip Symonds, Sara Alderweireldt, Olena Karacheban, Vieri Candelise, Lana Beck, Daniel John Karmgard, Manfred Jeitler, Ted Kolberg, Muhammad Shoaib, Claude Charlot, Burton Betchart, Reddy Pratap Gandrajula, Fabrizio Palla, Ivan Glushkov, Nathaniel Woods, Alexis Fagot, Evangelos Paradas, Kevin Burkett, Cristóvão Beirão Da Cruz E Silva, V. Milosevic, Rylan Conway, Matthias Ulrich Mozer, Massimiliano Chiorboli, Marius Preuten, John N. Wood, Johannes Brandstetter, Alexander Malakhov, Efe Yazgan, Luigi Benussi, Gouranga Kole, Irving Daniel Sandoval Gonzalez, Eddi A De Wolf, Arthur Moraes, Hui Li, Salvatore My, James Dolen, Freya Blekman, Ilse Krätschmer, David Michael Morse, Aditee Rane, Kai-Feng Chen, Ettore Focardi, Andrew Melo, Owen Baron, Eric Spencer, Steve Schnetzer, Saranya Ghosh, Klaas Padeken, Dominik Haitz, Renato Campanini, Gautier Hamel de Monchenault, Juan Alcaraz Maestre, Ahmad Borzou, Chiara La Licata, Raphael Granier de Cassagnac, Darien Wood, Jyothsna Rani Komaragiri, Satyaki Bhattacharya, Eric Takasugi, Isabell-Alissandra Melzer-Pellmann, Nicholas John Hadley, Mark Turner, Jehad Mousa, Karl Matthew Ecklund, Rohan Bhandari, Vinay Hegde, Saptaparna Bhattacharya, David Zou, Andrey Korytov, P. Chang, Eduardo De Moraes Gregores, Ashfaq Ahmad, Ashim Roy, J. C. Sanabria, Matthew Jones, Juan Garcia-Ferrero, Alexei Raspereza, Jung-Hyun Kim, Supratik Mukhopadhyay, Jan Krolikowski, Luiz Mundim, Duccio Abbaneo, Clemens Wöhrmann, Michal Simon, Salvatore Nuzzo, S. Bilmis, Philippe Bloch, Victor Golovtsov, Grant Riley, Robert Fischer, Lorenzo Bianchini, Katarzyna Romanowska-Rybinska, Jimin George, Ana Ovcharova, Anna Julia Zsigmond, Andrea Venturi, Ta-Wei Wang, Piet Verwilligen, Stefan Spanier, Pawel de Barbaro, Alexander Dermenev, Adam Elwood, Nikolai Krasnikov, Sami Lehti, Adish Vartak, Patricia Lobelle Pardo, Ivan Shvetsov, Igor Golutvin, Mircho Rodozov, Metin Yalvac, Stephan Lammel, Hugo Delannoy, David Stuart, Daniel Noonan, Alice Mignerey, Salim Cerci, Olaf Behnke, Günter Flügge, Qiao Xu, Tyler Ruggles, David Petyt, Dan Knowlton, Xin Shi, Hans Rykaczewski, Ivica Puljak, Hans Reithler, Ben Bylsma, Roberto Tenchini, Meng Xiao, Andrew Mehta, Alexandre Léonard, Jacobo Konigsberg, Young Do Oh, Maria Aldaya Martin, Joseph Goodell, Stephen Sanders, Wesley H Smith, Stefan Gundacker, Ravi Janjam, Siddharth Narayanan, Anton Karneyeu, Leonard Apanasevich, Alexey Svyatkovskiy, Jochen Schieck, S. 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Yetkin, Alberto Sánchez Hernández, Sinan Sagir, Pasquale Musella, Marta Felcini, Joao Pela, Thomas Hebbeker, Fabrizio Fabbri, Shervin Nourbakhsh, John Bradmiller-Feld, Rino Castaldi, John Hakala, Alexander Bylinkin, Songkyo Lee, Charalambos Nicolaou, Niki Saoulidou, Zhengcheng Tao, Sercan Sen, Y. H. 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Hughes, Viesturs Veckalns, Cecilia Elena Gerber, Dave Winn, Arnd Meyer, Atanu Modak, Francisco Yumiceva, Valentina Gori, Bastian Kargoll, Ritva Kinnunen, Marco Cipriani, Peter Elmer, Petar Maksimovic, Dario Bisello, Pascal Paganini, Jiyeon Han, Patrick Janot, Mikhail Dubinin, Wei Li, Thorsten Chwalek, Hannsjoerg Artur Weber, Wei Xie, Rainer Wallny, David Stickland, Gian Michele Innocenti, Livia Soffi, Christopher Seez, Daniel Pitzl, Matthew Carver, Ivan Amos Cali, Joaquin Emilo Siado, Ada Solano, Maksat Haytmyradov, Paolo Montagna, Othmane Bouhali, Norbert Neumeister, Philip Baringer, Hua Wei, George Stephans, Dominik Nowatschin, Pietro Vischia, Fionn Ball, Agnieszka Zagoździńska, Cristina Biino, Ivan Mikulec, Francesco Micheli, Philipp Pigard, Gul Gokbulut, David Mason, Luigi Moroni, Luca Lista, Gaetano-Marco Dallavalle, L. Wendland, Joao Seixas, Francisco Matorras, John A Coughlan, Michael Wang, Savvas Kyriacou, Denis Rathjens, V. A. Giakoumopoulou, Salvatore Costa, Indara Suarez, James G Branson, Tariq Aziz, Dave M Newbold, Jesus Marco, David Krofcheck, Jonathan Hollar, Yong Ban, Ajeeta Khatiwada, Willis Lin, Anirban Saha, Marko Dragicevic, Willard Johns, Andrew Evans, Ekaterina Avdeeva, Roberto Leonardi, Markus Merschmeyer, Arie Bodek, Mohammed Zakaria, Ozlem Kaya, Sevil Salur, Shalhout Shalhout, Brandon Allen, Dustin Burns, Nishu Nishu, Urs Langenegger, Martino Dall'Osso, Michael Buttignol, Christopher Clarke, Adrian Byszuk, Brian Dorney, Thomas Bergauer, Michael Planer, Sanjeev Kumar, Crisostomo Sciacca, Maxim Goncharov, Richard D Field, Marco Pieri, Francesco Costanza, Andreas Psallidas, Christopher George, Douglas Wright, Giacomo Fedi, Alice Cocoros, David Fehling, Ian R Tomalin, David Saltzberg, José David Ruiz Alvarez, Vladimir Mossolov, Vladimir Palichik, Stephen Mrenna, Afiq Aizuddin Bin Anuar, Marc Weinberg, Wolfgang Treberer-Treberspurg, Marco Zanetti, Sarmad Masood Shaheen, Tae Jeong Kim, Michael Murray, Jakob Salfeld-Nebgen, Kunal Kothekar, Jessica Leonard, Marco Rossini, Nazar Bartosik, Enrique Palencia Cortezon, Brian Calvert, Marvin Johnson, Anthony Poll, Michael Squires, Gian Mario Bilei, Pavel Jez, Marco De Mattia, C. A. Carrillo Montoya, Silvia Goy Lopez, Jingzhou Zhao, Jongseok Lee, Vladimir Cherepanov, Hasan Ogul, Daniel Duggan, Loic Quertenmont, Aram Apyan, John Perry Cumalat, Swagata Mukherjee, Valentin Sulimov, Pedro Silva, Philip H Butler, Prolay Mal, B. Knapp, Regina Demina, Inkyu Park, Oliver Gutsche, Sourabh Dube, Terence Libeiro, Douglas Burns, Jia Fu Low, Andreas Pfeiffer, Kreso Kadija, Jeffrey Richman, Gilvan Alves, Matthew Walker, Salvatore Di Guida, Hyunyong Kim, Kirill Skovpen, Maciej Górski, Anna Kropivnitskaya, Matthias Schröder, Alberto Santoro, Tom Cornelis, Shivali Malhotra, Gunter Quast, Ennio Monteil, Aldo Penzo, Natalie Heracleous, Manqi Ruan, Monika Grothe, Grigory Safronov, Vyacheslav Valuev, Albert De Roeck, Ren-Yuan Zhu, Matteo Cremonesi, Jaehoon Lim, Pascal Vanlaer, Luciano Barone, Richard Breedon, Erik Butz, Hannes Mildner, Souvik Das, Tristan Du Pree, Márton Bartók, Natalia Lychkovskaya, Jui-Fa Tsai, Timo Peltola, Michael Schmitt, Alexander Ershov, Carlo Rovelli, Emanuele Usai, Silvio Donato, Ezio Torassa, Harry Cheung, Andrew Johnson, Peter Schleper, Zhen Hu, Keith Ulmer, Zoltan Laszlo Trocsanyi, J. Conway, D. Del Re, Dong Hee Kim, Vincent Lemaitre, Paul Baillon, Artur Apresyan, Marc Besancon, Dinyar Rabady, Bibhuti Parida, Wolfram Dietrich Zeuner, Sergey Rusakov, David Futyan, Malgorzata Kazana, Olga Evdokimov, Junghwan Goh, Konstantin Androsov, Tai Sakuma, Livio Fanò, Lucie Gauthier, Kevin Deroover, Anterpreet Kaur, Emine Gurpinar, Sabino Meola, Roberto Covarelli, Sergio Cittolin, Jared Sturdy, Kaya Tatar, Sandra S. Padula, Alexey Volkov, Yutaro Iiyama, Thomas Weiler, Paolo Vitulo, Maximilian Knut Kiesel, William J Spalding, Jay Roberts, Intae Yu, Stefano Bianco, Yury Ivanov, Andre Sznajder, Serdal Damarseckin, Yuri Gershtein, Emmanuelle Perez, Cristina Riccardi, Daniele Vadruccio, Claude Nuttens, Francois Lagarde, Anna Elliott-Peisert, Vuko Brigljevic, Zukhaimira Zolkapli, David Taylor, Aran Garcia-Bellido, Sho Maruyama, Debarati Roy, Mauro De Palma, Menglei Sun, Jeremy Mans, Zainol Abidin Ibrahim, Konstantinos Theofilatos, Franco Ligabue, Sandor Czellar, Manuel Giffels, Pavel Bunin, Gustavo Gil Da Silveira, Guo-Ming Chen, Sasa Micanovic, Arabella Martelli, Victoria Zhukova, Soureek Mitra, Muhammad Ahmad, Felix Hoehle, Suman Bala Beri, Vivian O'Dell, Kenneth Long, Ernesto Migliore, Lucija Sudic, Hans-Jürgen Simonis, Todd Adams, Wit Busza, Andrea Carlo Marini, Alexander Tapper, Vyacheslav Krutelyov, Suvadeep Bose, Luisa Fernanda Chaparro Sierra, Deborah Pinna, Caterina Vernieri, Emanuela Barberis, Avraham Yagil, Nicolo Magini, Michael Dittmar, Steven Kaplan, Aleksandar Aleksandrov, Frank Raupach, Jacob Linacre, Zaixing Mao, Bernard Ille, Dustin Anderson, Christian Hartl, Dinko Ferencek, Lina Milena Huertas Guativa, Giovanni Franzoni, Evrim Ersin Kangal, Ashok Kumar, Krishna Thapa, M. Miñano Moya, Eliza Melo Da Costa, Mario Pelliccioni, Anne Dabrowski, Tulika Bose, Muriel Vander Donckt, Wuming Luo, Giovanni Abbiendi, Amandeep Kaur Kalsi, Leonard Spiegel, David Miller, Francesco Romeo, Robert Klanner, Camille Beluffi, Darin Acosta, Youngkwon Jo, Kristian Allan Hahn, Daniele Bonacorsi, Ricardo Lopez-Fernandez, Davide Cieri, Shimaa Abu Zeid, Giovanni Polese, Svenja Schumann, Rami Kamalieddin, Bodhitha Jayatilaka, Yu-Wei Chang, Christian Sander, Jorge F de Trocóniz, Guillaume Garcia, Giuseppe Barbagli, Simone Pigazzini, James Keaveney, Constantin Heidegger, Gianni Zumerle, Mark Foerster, Sunil Bansal, Pierre Lecomte, Stefano Lacaprara, Nicholas Smith, Emanuele Di Marco, Andrey Leonidov, Jean-Charles Fontaine, Anton Dimitrov, Andrea Gozzelino, Werner Lustermann, Andromachi Tsirou, Tatiana Medvedeva, and Jordan Nash
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Luminosity (scattering theory), Large Hadron Collider, 010308 nuclear & particles physics, Branching fraction, High Energy Physics::Phenomenology, Electroweak interaction, 01 natural sciences, Standard Model, Nuclear physics, Cross section (physics), 0103 physical sciences, High Energy Physics::Experiment, Production (computer science), Nuclear Experiment, 010306 general physics, Lepton
Abstract: Four-lepton production in proton–proton collisions, pp→(Z/γ⁎)(Z/γ⁎)→ℓ+ℓ−ℓ′+ℓ′−, where ℓ,ℓ′=e or μ, is studied at a center-of-mass energy of 13 TeV with the CMS detector at the LHC. The data sample corresponds to an integrated luminosity of 2.6 fb$^{−1}$. The ZZ production cross section, σ(pp→ZZ)=14.6−1.8+1.9(stat)−0.3+0.5(syst)±0.2(theo)±0.4(lumi)pb, is measured for events with two opposite-sign, same-flavor lepton pairs produced in the mass region 604 GeV for all opposite-sign, same-flavor lepton pairs. The results are in agreement with standard model predictions.
Published: 2016

38. Search for lepton flavour violating decays of the Higgs boson to eτ and eμ in proton–proton collisions at s=8 TeV

Author: Richard Vidal, L. Alunni Solestizi, Matthias Kasemann, Paola Salvini, Samuel Bein, Marcos Fernandez, Florian Beaudette, Alexander Gude, Andrew Kubik, Daniel Arcaro, Marek Walczak, Marcella Diemoz, Marco Cardaci, Alexandre Zabi, Vladimir Rekovic, Ian Shipsey, Matthew Chasco, Rachel Yohay, Sergio P Ratti, Jian Sun, Artur Kalinowski, Nikolai Shumeiko, Bora Akgun, B. Tali, Luigi Guiducci, Gregory R Snow, P. Verdier, Marino Missiroli, Andrius Juodagalvis, Vladimir Karjavin, O. Davignon, Kerstin Borras, Frank Chlebana, Kuntal Mondal, Giovanni Organtini, Paolo Spagnolo, Jared Turkewitz, Igor Volobouev, Fábio Lúcio Alves, Frank Hartmann, Luciano Orsini, Luca Pacher, Vasile Mihai Ghete, Claire Shepherd-Themistocleous, Bo Liu, Dong-Chul Son, Liliana Teodorescu, Adolf Bornheim, Aaron Bundock, Katerina Lipka, Martin Kirakosyan, Stefan Michael Heindl, W. Ji, Lindsey Gray, Alberto Belloni, Attilio Santocchia, Jeson Jacob, Jean Fay, Igor Dremin, Abideh Jafari, Nathan Mirman, Antonis Agapitos, Thi Hien Doan, Benoit Roland, Daniel Denegri, Caleb Fangmeier, Joseph Goodell, Stephen Sanders, Wesley H Smith, Gyorgy Bencze, Riccardo Paramatti, Andrea Giammanco, Guido Tonelli, Stefano Colafranceschi, C. Scharf, Betty Calpas, J. C. Ruiz Vargas, W. A. T. Wan Abdullah, Jamal Rorie, Jason Gilmore, Marco Paganoni, Don Lincoln, Mukund Varma, Gennady Mesyats, Hafeez R Hoorani, Howard Wells Wulsin, F. Vazquez Valencia, Alexander Nikitenko, Hartmut Stadie, James Zabel, F. Mohamad Idris, Daniel John Karmgard, Manfred Jeitler, Fabrizio Palla, Dimitri Bourilkov, Andrew Melo, Andrew Whitbeck, Owen Baron, Vivekanand Jha, Sebastian Thüer, Steve Schnetzer, Saranya Ghosh, Klaas Padeken, Dominik Haitz, Renato Campanini, Viktor Veszpremi, Abdulla Abdulsalam, Carlos Lourenco, Alexander Nehrkorn, Gianluca Petrillo, Mia Tosi, Maria Hempel, Min Sang Ryu, Jasvinder A. Singh, Luca Perrozzi, Manfred Krammer, Kevin Sung, Florent Lacroix, Dipanwita Dutta, Konstanty Sumorok, Semiray Girgis, Andris Skuja, Sébastien Brochet, Ana Yaiza Rodríguez-Marrero, Ivica Puljak, Hans Reithler, Ben Bylsma, R. Lopes De Sá, Roberto Tenchini, Meng Xiao, A. J. Bell, Alexei Safonov, Daniele Pedrini, I. Gonzalez Caballero, B. Gomez Moreno, Shabnam Jabeen, Dmytro Kovalskyi, Gyorgy Vesztergombi, F. Gasparini, Nikoloz Skhirtladze, E. Navarro De Martino, Zeljko Antunovic, Claudia-Elisabeth Wulz, Christoph Paus, Wolfgang Waltenberger, Piergiulio Lenzi, Luca Malgeri, Alexandre Aubin, Ajeet Kumar, Janos Erö, Panagiotis Katsas, Ian Fisk, Julia Velkovska, Tobias Lapsien, Burak Bilki, Frank Jm Geurts, Nicolò Trevisani, Gianluca Cerminara, Giuseppe Codispoti, Pavel Sorokin, Hui Li, Salvatore My, Quentin Ingram, Igor Vorobiev, Josef Hammer, Prashant Shukla, Sudha Ahuja, Nikolai Gorbounov, Halil Saka, Pietro Govoni, Maryam Zeinali, Patrick Jarry, James Faulkner, A. Escalante Del Valle, Pawandeep Jandir, Vardan Khachatryan, Martin Bodlak, Alexandre Léonard, Jacobo Konigsberg, R. Gray, Nicholas Wardle, Tao Huang, Benedikt Maier, Gregor Kasieczka, Marco Meschini, Lesya Shchutska, Andrea Massironi, André Rosowsky, Andrew Ivanov, Siarhei Shulha, Paolo Gunnellini, Sam Daniel Mullin, Inga Bucinskaite, H. S. Chen, Maria Savina, Anne-Laure Pequegnot, Edmund Berry, Jose M Hernandez, Guillermo Breto, Batool Safarzadeh, Juliet Ritchie Patterson, Caglar Zorbilmez, Emrah Tiras, Toyoko Orimoto, D. W. Kim, Luciano Romero, Giacomo Sguazzoni, Alan Campbell, Bolek Wyslouch, M. A. B. Ali, Felix Bachmair, Cory Fantasia, Francesco Navarria, Konrad Deiters, Maria Spiropulu, Lucas Brito, Panos A Razis, James Dolen, Benjamin Charles Radburn-Smith, Joosep Pata, Colin Bernet, Freya Blekman, Steven R. Simon, Y. W. Chang, Nadia Pastrone, Martti Raidal, Florian Scheuch, Boaz Klima, Richard G Kellogg, Kevin Nash, Valentina Dutta, Michael Tytgat, Emmanuel Contreras-Campana, Pamela Klabbers, Ilse Krätschmer, David Michael Morse, G. Hamel de Monchenault, Anna Cimmino, Eunhyang Kwon, J. Yelton, Christine Mclean, M. Chamizo Llatas, Joao Varela, Leander Litov, Joshy George, Jean-Pierre Merlo, D. M. Strom, Matthew Herndon, Alessio Bonato, G. Kozlov, Fabio Cossutti, H. Topakli, Brendan Diamond, Giulia D'imperio, Jovan Milosevic, Darren Puigh, Vitaliano Ciulli, Apostolos Panagiotou, Benjamin Kilminster, Kai-Feng Chen, John Gabriel Acosta, Christopher West, Zhoudunming Tu, Si-Jin Qian, David Lange, Isabel Ojalvo, Georgia Karapostoli, Youn Roh, Olga Evdokimov, Junghwan Goh, Livio Fanò, Lucie Gauthier, Barry Blumenfeld, Robin Erbacher, Ayman Mahrous, Senta Greene, Sergey Shmatov, Douglas Rank, Paul Lujan, Daniela Bortoletto, M. Centis Vignali, Emine Gurpinar, Merve Ozcan, Christopher George Tully, Florian Zenoni, John Strologas, J. Fernandez Menendez, Ian Anderson, Rebekka Sophie Höing, Sridhara Dasu, Emilio Meschi, H. El Mamouni, Rocky Bala Garg, Joanne Cole, Narumon Suwonjandee, Christopher Bruner, Eija Tuominen, Luigi Fiore, Lucia Perrini, Pierre Piroué, Alexander Mott, Sabino Meola, Sergey Senkin, Marius Preuten, Charles Maguire, Theodoros Geralis, Alexander Belyaev, Claudio Campagnari, Colin Baus, Hanno Perrey, Manoj Jha, Vipin Bhatnagar, Danilo Piparo, Matthias Schröder, Ettore Focardi, Jeannine Wagner-Kuhr, Vallary Bhopatkar, John Rander, Jozsef Molnar, Valerio Re, Metin Yalvac, Andrea Rizzi, Amr Radi, Stephan Lammel, Clemens Wöhrmann, Michal Simon, Leonid Tourtchanovitch, Kristen Flowers, Raffaella Radogna, Raman Khurana, Michael Krohn, Jeremie Alexandre Merlin, Piotr Zalewski, Daniel Noonan, Alexandros Attikis, Xinmei Niu, Vitaly Smirnov, Nayana Majumdar, Dragos Velicanu, Qamar Hassan, Valentin Knünz, A. 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Aldaya Martin, Harvey B Newman, Jeffrey Berryhill, Ennio Monteil, Aldo Penzo, Natalie Heracleous, Tongguang Cheng, Andras Hazi, T. A. Verlage, Ioannis Evangelou, Andrew Carnes, Jordan Tucker, Igor Katkov, Nuno Leonardo, Brian Pollack, Simon Fink, Sergo Jindariani, J. Schwandt, Ece Aşılar, Clara Jorda, Richard Barbieri, Gagan Bihari Mohanty, Alessandro Braghieri, Gregory Rakness, Teimuraz Lomtadze, Gabor Istvan Veres, Claudio Caputo, Alexandre Mertens, Pasquale Musella, Sharon Hagopian, Ralf Ulrich, Juliette Alimena, E. J. Tonelli Manganote, Khristian Kotov, Krzysztof Piotrzkowski, Ekaterina Kuznetsova, Lloyd Stanley Durkin, Yvonne Kuessel, Vincenzo Innocente, Ashutosh Bhardwaj, Helmut Vogel, Elisabetta Gallo, M. Lo Vetere, J. A. Gomez, Kelly Beernaert, Konstantinos Kousouris, Joshua Bendavid, Nicanor Colino, Lei Feng, Kamuran Dilsiz, Steven Wasserbaech, Eleni Ntomari, Paolo Rumerio, Lorenzo Uplegger, Jan Hoss, William T. Ford, Andrea Bocci, P. 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Salazar Ibarguen, Mihee Jo, Brian L Winer, Mehmet Özgür Sahin, Donato Creanza, Robin Aggleton, Marc Dobson, Heiner Tholen, Angela Mehta, Ferenc Sikler, Dayong Wang, Mauro Verzetti, Mario Kadastik, B. A. Barnett, Giorgio Apollinari, Ulf Behrens, Seth Cooper, Charles Mueller, Linda Finco, Ferhat Ozok, Teruki Kamon, Srecko Morovic, G. L. Pinna Angioni, Pierluigi Paolucci, Roberto Carlin, Johannes Haller, J. F. Tsai, Shuai Liu, Bruno Casal, Ioannis Papadopoulos, Tapomoy Guha Sarkar, Pierre Depasse, Alexey Vorobyev, Daniel Teyssier, T. Lenzi, Keith Rose, R. Frühwirth, Erica Brondolin, Alexis Pompili, Louie Corpe, Stephen Wimpenny, Henning Flacher, Vyacheslav Klyukhin, M. Van De Klundert, Guillaume Garcia, Gian Michele Innocenti, A. Ranieri, Livia Soffi, Tommaso Dorigo, Alexis Descroix, Sandra Malvezzi, W. L. Prado Da Silva, Pietro Faccioli, Hamit Mermerkaya, D. H. 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Olmedo Negrete, Jasper Lauwers, Matthias Komm, Maurizio Pierini, David Cussans, Christopher Martin, Josef Hrubec, Constantin Heidegger, Paul Papacz, Dean Hidas, Daryl Hare, Luca Brianza, Bryan Dahmes, Marco Cuffiani, Giovanni Petrucciani, Dawn Leslie, A. Di Francesco, Ulrich Heintz, Arun Kumar, Helena Bialkowska, Erhan Gülmez, Kaori Maeshima, Aurelijus Rinkevicius, Martin Erdmann, Jiawei Fan, Sergey Petrushanko, Christopher Cowden, Patricia McBride, Krzysztof Doroba, Christopher Seez, Ada Solano, Lev Uvarov, Rajdeep Mohan Chatterjee, Jaehyeok Yoo, Raymond Patrick Kenny Iii, A. A. Abdelalim, Benjamin Michlin, Anita Topkar, Agnieszka Zagozdzinska, Elvire Bouvier, Giuseppe Iaselli, Umesh Joshi, E. A. De Wolf, Matti J Kortelainen, Roberto Rossin, Andrew Rose, Oliver Buchmuller, Stilianos Kesisoglou, Scott Thomas, Piero Giorgio Verdini, Can You, Kenneth Bloom, Thomas Perry, P. G. 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Cihangir, Andrii Gizhko, Gero Flucke, Manfred Paulini, Victor Krychkine, Pierluigi Bortignon, Matteo Sani, Andreas Nowack, Ugo Gasparini, Veikko Karimäki, Nicola Cavallo, Sara Fiorendi, Allison Reinsvold, Vasken Hagopian, Zeynep Demiragli, Yalcin Guler, Roger Wolf, Andrew Ackert, Yongsun Kim, Lev Dudko, Jeremy Andrea, Hong Ni, Pierluigi Zotto, S. Lee, Hwi Dong Yoo, Zijun Xu, Robert Bainbridge, Koushik Mandal, Ryan Kelley, Paraskevas Sphicas, Lingshan Xu, Gobinda Majumder, Stefano Ragazzi, Jane Nachtman, R. Gonzalez Suarez, Sergio F Novaes, Morgan Lethuillier, Charles Dietz, Yasar Onel, Ignacio Redondo, Benjamin Stieger, Hyun-Chul Kim, Steven Worm, Yurii Maravin, Vladimir Gavrilov, Aleko Khukhunaishvili, Sonaina Undleeb, Markus Friedl, A. C. Le Bihan, Hannes Jung, Alexander Zhokin, Martijn Mulders, Darin Baumgartel, Anna Colaleo, Kamal Lamichhane, Mingming Yang, Martino Margoni, Jochen Ott, Alberto Benvenuti, Maria Agnese Ciocci, Dave Pellett, Marko Kovac, Maria Florencia Canelli, Fabrizio Ferro, Thomas Ferbel, Dan Green, Lars Sonnenschein, Marta Ruspa, Stepan Obraztsov, Anshul Kapoor, Gabriella Pugliese, I. Van Parijs, Jason Gran, Kevin Lannon, G. Della Ricca, Guenakh Mitselmakher, B. Grynyov, Jordan Damgov, Peter Hansen, Kisung Lee, Claude Amsler, Brent Yates, Laurent Favart, Cristian Pena, Thomas Reis, Martin Lipinski, Kristin Goebel, Frank Würthwein, Manas Maity, Alexi Mestvirishvili, Ulrich Goerlach, David Petyt, Dan Knowlton, W. Van Doninck, Xin Shi, Steve Nahn, Paolo Capiluppi, James Rohlf, Hans Rykaczewski, Zhaoxia Meng, Chiara Mariotti, Alexey Volkov, Carlos Avila, Sergei Bitioukov, Alessio Boletti, Matteo Marone, Jie Zhang, John L Wood, Francesca Romana Cavallo, Viktor Savrin, Mitchell Wayne, Karol Bunkowski, Jan Veverka, Ricardo Eusebi, Giorgio Maggi, Sadia Khalil, C. Fernandez Bedoya, Stefan Grünendahl, Amedeo Staiano, Robert Schöfbeck, Roberto Sacchi, Natascha Hörmann, Tejinder Virdee, Philip Harris, D. Matos Figueiredo, Noemi Beni, K. S. Lee, M. Della Negra, Maria Isabel Josa, Nicolò Tosi, Camilla Galloni, Shashikant Dugad, Eva Halkiadakis, Seth Conrad Zenz, I. Heredia-De La Cruz, Andrew Godshalk, Frank Glege, Iurii Antropov, Deborah Duchardt, Vincenzo Daponte, M. Vidal Marono, Daniele Marconi, S. De Visscher, Julia Thom, Peter Robmann, Alexey Finkel, Finn Rebassoo, Tiziano Camporesi, L. Brigliadori, Patrick Dunne, Seema Sharma, Volker Blobel, Louise Skinnari, Nural Akchurin, N. G. Redaelli, Joshua Hardenbrook, Lucia Silvestris, Sheng Wang, Frank Jensen, Neeti Parashar, Klaus Rabbertz, Maria Girone, Martina Malberti, Igor Lokhtin, Myriam Schönenberger, Zachary Lesko, Paul Turner, Robert M Brown, Jay Dittmann, Dieter Renker, Petar Adzic, Maria Margherita Obertino, Alajos Makovec, Muhammad Gul, P. Van Mulders, Michele Gallinaro, Junquan Tao, Giorgia Miniello, Peter Wittich, Francesco Fabozzi, Michal Olszewski, Christine O'Brien, Stefaan Tavernier, Diego Ciangottini, Andrea Perrotta, Fuqiang Wang, Justin Pilot, Metin Ata, Petr Moisenz, David Ja Cockerill, Wolfgang Lange, Gianni Masetti, Erik Gottschalk, Andrea Delgado, Duncan Leggat, Yuriy Pakhotin, Wolfgang Funk, G. Gomez Ceballos, Nikos Varelas, Grzegorz Brona, Arun Luthra, James Hirschauer, Jordon Rowe Adams, Ulascan Sarica, Helen F Heath, Mariana Vutova, Ryo Yonamine, Nicholas Mucia, Himali Kalakhety, Yeng-Ming Tzeng, Matthieu Marionneau, Arne-Rasmus Draeger, Mehmet Zeyrek, Kenichi Hatakeyama, Anna Woodard, Magdalena Malek, Petr Levchenko, Marco Costa, Norbert Tambe, Nikolai Golubev, David Nash, R. Stringer, Philip Lawson, M. De Palma, Mark Grimes, Mark Baber, Thomas Esch, Otman Charaf, Marcel Rieger, Anders Ryd, Gavin Davies, Simon Knutzen, Javier Duarte, Jacopo Pazzini, Sergey Vavilov, Hadi Behnamian, Alexander Lanev, Susan Dittmer, Kalyanmoy Chatterjee, Georgios Daskalakis, Mythra Varun Nemallapudi, Alessandra Romero, Sergei Gninenko, Nicolas Filipovic, Senka Duric, Guler Karapinar, Erik Dietz-Laursonn, Süleyman Durgut, John Paul Chou, Brian Paul Padley, Fabrizio Margaroli, Nairit Sur, J. Piedra Gomez, Gregory Iles, Dominick Olivito, S. Roy Chowdhury, Colin Jessop, and M. Calderon De La Barca Sanchez
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, 010308 nuclear & particles physics, European research, High Energy Physics::Phenomenology, Library science, Computer Science::Digital Libraries, 01 natural sciences, Regional development, 0103 physical sciences, media_common.cataloged_instance, High Energy Physics::Experiment, Christian ministry, Science policy, European union, 010306 general physics, media_common
Abstract: We acknowledge the enduring support for the construc-tion and operation of the LHC and the CMS detector provided by the following funding agencies: BMWFW and FWF (Austria); FNRS and FWO (Belgium); CNPq, CAPES, FAPERJ, and FAPESP (Brazil); MES (Bulgaria); CERN; CAS, MOST, and NSFC (China); COLCIEN-CIAS (Colombia); MSES and CSF (Croatia); RPF (Cyprus); SENESCYT (Ecuador); MoER, ERC IUT and ERDF (Estonia); Academy of Fin-land, MEC, and HIP (Finland); CEA and CNRS/IN2P3 (France); BMBF, DFG, and HGF (Germany); GSRT (Greece); OTKA and NIH (Hun-gary); DAE and DST (India); IPM (Iran); SFI (Ireland); INFN (Italy); MSIP and NRF (Republic of Korea); LAS (Lithuania); MOE and UM (Malaysia); BUAP, CINVESTAV, CONACYT, LNS, SEP, and UASLP-FAI (Mexico); MBIE (New Zealand); PAEC (Pakistan); MSHE and NSC (Poland); FCT (Portugal); JINR (Dubna); MON, RosAtom, RAS and RFBR (Russia); MESTD (Serbia); SEIDI and CPAN (Spain); Swiss Funding Agencies (Switzerland); MST (Taipei); ThEPCenter, IPST, STAR and NSTDA (Thailand); TUBITAK and TAEK (Turkey); NASU and SFFR (Ukraine); STFC (United Kingdom); DOE and NSF (USA). Individuals have received support from the Marie-Curie pro-gramme and the European Research Council and EPLANET (Euro-pean Union); the Leventis Foundation; the Alfred P. Sloan Foun-dation; the Alexander von Humboldt Foundation; the Belgian Federal Science Policy Office; the Fonds pour la Formation a la Recherche dans l’Industrie et dans l’Agriculture(FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technolo-gie (IWT-Belgium); the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Council of Science and In-dustrial Research, India; the HOMING PLUS programme of the Foundation for Polish Science, cofinanced from European Union, Regional Development Fund, the Mobility Plus programme of the Ministry of Science and Higher Education, the OPUS pro-gramme contract 2014/13/B/ST2/02543 and contract Sonata-bis DEC-2012/07/E/ST2/01406 of the National Science Center (Poland); the Thalis and Aristeia programmes cofinanced by EU-ESF and the Greek NSRF; the National Priorities Research Program by Qatar National Research Fund; the Programa Clarin-COFUND del Prin-cipado de Asturias; the Rachadapisek Sompot Fund for Postdoc-toral Fellowship, Chulalongkorn University and the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thai-land); and the Welch Foundation, contract C-1845.
Published: 2016

39. Efficacy of growth factors for the treatment of peri-implant diseases: a systematic review and meta-analysis

Author: Franz Josef Strauss, Simon Pardiñas-López, Ryan Richard Ruff, and Ismael Khouly
Subjects: medicine.medical_specialty, Peri-implant mucositis, Bleeding on probing, law.invention, 03 medical and health sciences, 0302 clinical medicine, Randomized controlled trial, law, Internal medicine, medicine, Mucositis, Humans, General Dentistry, Gingival recession, Dental Implants, Stomatitis, business.industry, 030206 dentistry, medicine.disease, Peri-Implantitis, Confidence interval, Strictly standardized mean difference, 030220 oncology & carcinogenesis, Meta-analysis, medicine.symptom, business
Abstract: The aim of this study was to conduct a systematic review and meta-analysis on the efficacy of growth factors (GF) on clinical outcomes after treatment (surgical/non-surgical) of peri-implant diseases (peri-implant mucositis and peri-implantitis). A protocol was developed to answer the following focused question: Is there any difference for the use of GF for treatment of peri-implant diseases versus comparative GF treatment or without GF? Electronic database and manual searches were independently conducted to identify randomized controlled trials (RCTs). Publications were selected based on eligibility criteria and then assessed for risk-of-bias using the Cochrane Handbook. The primary outcome was probing depth (PD) and bleeding on probing (BOP) reduction along with changes in vertical defect depth (VDD). Changes in clinical attachment level, gingival recession, and plaque index, among others, were studied as secondary outcomes. Based on primary outcomes, random-effects meta-analysis was conducted. A total of five RCTs were included. GF enhance the reduction of PD (standardized mean difference (SMD) = − 1.28; 95% confidence interval (CI) − 1.75, − 0.79; p =
Published: 2019

40. Platelet-rich fibrin elicits an anti-inflammatory response in macrophages in vitro

Author: Jila, Nasirzade, Zahra, Kargarpour, Sadegh, Hasannia, Franz Josef, Strauss, and Reinhard, Gruber
Subjects: Lipopolysaccharides, Macrophages, blood platelets, arginase, Anti-Inflammatory Agents, Macrophage Activation, digestive system diseases, cytokines, Mice, RAW 264.7 Cells, Platelet-Rich Fibrin, Animals, Translational Periodontology, Original Article, anti‐inflammatory agents, platelet‐rich fibrin
Abstract: Background Platelet‐rich fibrin (PRF) serves as a reservoir of bioactive molecules to support wound healing and bone regeneration. The beneficial action of PRF might involve macrophage polarization from proinflammatory M1 toward pro‐resolving M2 phenotypes. This study aims to evaluate the effect of PRF on macrophage polarization. Methods Murine primary macrophages and RAW 264.7 cells were exposed to saliva and lipopolysaccharides (LPS) with and without PRF lysates obtained by repeated freeze‐thawing or the secretome of PRF membranes, termed PRF conditioned medium. The expression of the M1 marker genes interleukin 1β (IL1β) and interleukin 6 (IL6) along with the M2 markers arginase‐1 and chitinase‐like 3 (Chil3 or YM1) were evaluated by real time polymerase chain reaction. Immunoassay and immunofluorescence staining were performed for IL6 and p65 translocation, a subunit nuclear factor kappa‐light‐chain‐enhancer of activated B cells (NF‐kB), respectively. Results We report here that PRF lysates and PRF conditioned medium, the latter containing the secretome, greatly decreased the proinflammatory response of primary macrophages and RAW 264.7 cells as indicated by the expression of IL1β and IL6. The anti‐inflammatory activity of PRF lysates was further confirmed by IL6 immunoassay. Moreover, PRF lysates suppressed the translocation of p65 from the cytoplasm into the nucleus after incubation with saliva. In support of M2 polarization, PRF lysates and PRF conditioned medium enhanced the expression of arginase‐1 and YM1 in primary macrophages. Conclusion Our results indicate that PRF holds an anti‐inflammatory activity and shifts the macrophage polarization from an M1 toward an M2 phenotype.
Published: 2019

41. Platelet-rich fibrin suppresses in vitro osteoclastogenesis

Author: Zahra, Kargarpour, Jila, Nasirzade, Franz Josef, Strauss, Francesca, Di Summa, Sadegh, Hasannia, Heinz-Dieter, Müller, and Reinhard, Gruber
Subjects: NFATC Transcription Factors, Macrophage Colony-Stimulating Factor, RANK Ligand, Osteoclasts, Cell Differentiation, digestive system diseases, Mice, Osteogenesis, Platelet-Rich Fibrin, Animals, Translational Periodontology, Original Article, Bone Resorption, platelet‐rich fibrin, alveolar ridge augmentation
Abstract: Background Platelet‐rich fibrin (PRF) membranes can preserve alveolar ridge dimension after tooth extraction. Thus, it can be presumed that PRF suppresses the catabolic events that are caused by osteoclastic bone resorption. Methods To address this possibility, we investigated the impact of soluble extracts of PRF membranes on in vitro osteoclastogenesis in murine bone marrow cultures. Osteoclastogenesis was induced by exposing murine bone marrow cultures to receptor activator of nuclear factor kappa B ligand (RANKL), macrophage colony‐stimulating factor (M‐CSF) and transforming growth factor‐beta 1 (TGF‐β1) in the presence or absence of PRF. Osteoclastogenesis was evaluated based on histochemical, gene expression, and resorption analysis. Viability was confirmed by formation of formazan crystals, live‐dead staining and caspase‐3 activity assay. Results We report here that in vitro osteoclastogenesis is greatly suppressed by soluble extracts of PRF membranes as indicated by tartrate‐resistant acid phosphatase (TRAP) staining and pit formation. In support of the histochemical observations, soluble extracts of PRF membranes decreased expression levels of the osteoclast marker genes TRAP, Cathepsin K, dendritic cell‐specific transmembrane protein (DCSTAMP), nuclear factor of activated T‐cells (NFATc1), and osteoclast‐associated receptor (OSCAR). PRF membranes, however, cannot reverse the process once osteoclastogenesis has evolved. Conclusion These in vitro findings indicate that PRF membranes can inhibit the formation of osteoclasts from hematopoietic progenitors in bone marrow cultures. Overall, our results imply that the favorable effects of PRF membranes in alveolar ridge preservation may be attributed, at least in part, by the inhibition of osteoclastogenesis.
Published: 2019

42. Caffeic acid phenethyl ester protects against oxidative stress and dampens inflammation via heme oxygenase 1

Author: Sigrun Eick, Reinhard Gruber, Alexandra Stähli, Ceeneena Ubaidha Maheen, Franz Josef Strauss, and Anton Sculean
Subjects: 0301 basic medicine, p38 mitogen-activated protein kinases, education, 610 Medicine & health, Inflammation, Pharmacology, medicine.disease_cause, Article, 03 medical and health sciences, chemistry.chemical_compound, Mice, 0302 clinical medicine, Caffeic Acids, Heat shock protein, medicine, Animals, Humans, Caffeic acid phenethyl ester, General Dentistry, Chemistry, NF-kappa B, 030206 dentistry, Propolis, Phenylethyl Alcohol, Heme oxygenase, lcsh:RK1-715, Oxidative Stress, 030104 developmental biology, lcsh:Dentistry, Knockout mouse, population characteristics, medicine.symptom, Oxidative stress, Heme Oxygenase-1, geographic locations
Abstract: Periodontal disease is associated with chronic oxidative stress and inflammation. Caffeic acid phenethyl ester (CAPE), which is a potent inducer of heme oxygenase 1 (HO1), is a central active component of propolis, and the application of propolis improves periodontal status in diabetic patients. Here, primary murine macrophages were exposed to CAPE. Target gene expression was assessed by whole-genome microarray, RT-PCR and Western blotting. The antioxidative and anti-inflammatory activities of CAPE were examined by exposure of the cells to hydrogen peroxide, saliva and periodontal pathogens. The involvement of HO1 was investigated with the HO1 inhibitor tin protoporphyrin (SnPP) and knockout mice for Nrf2, which is a transcription factor for detoxifying enzymes. CAPE increased HO1 and other heat shock proteins in murine macrophages. A p38 MAPK inhibitor and Nrf2 knockout attenuated CAPE-induced HO1 expression in macrophages. CAPE exerted strong antioxidative activity. Additionally, CAPE reduced the inflammatory response to saliva and periodontal pathogens. Blocking HO1 decreased the antioxidative activity and attenuated the anti-inflammatory activity of CAPE. In conclusion, CAPE exerted its antioxidative effects through the Nrf2-mediated HO1 pathway and its anti-inflammatory effects through NF-κB inhibition. However, preclinical models evaluating the use of CAPE in periodontal inflammation are necessary in future studies., Healthy gums: a little help from honeybees Propolis, also known as ‘honeybee glue,’ may protect teeth and gums against periodontal disease. In periodontal disease, chronic inflammation and oxidative damage harm gum tissue and lead to tooth loss; propolis has been shown to improve periodontal health for patients with diabetes. Bees make propolis by mixing beeswax, honey, plant resins and their own saliva, and use it to patch honeycomb and prevent growth of microbes in the hive. Reinhard Gruber of the Department of Oral Biology at the Medical University of Vienna and of the Department of Periodontology, University of Bern and co-workers investigated the effects of one of propolis’ active ingredients, caffeic acid phenethyl ester (CAPE), on oxidative stress and inflammation. They found that CAPE reduced oxidative damage and dampened inflammation; further investigation revealed the genetic basis of the beneficial effects, paving the way for future clinical studies. These results may help identify alternative treatments for periodontal disease.
Published: 2019
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43. TGF-β activity in acid bone lysate adsorbs to titanium surface

Author: Reinhard Gruber, Alexandra Stähli, Francesca Di Summa, Franz Josef Strauss, Guenther Schuldt, Fabiola Vaca, and Luiza Matos
Subjects: Surface Properties, 0206 medical engineering, 610 Medicine & health, 02 engineering and technology, Bone and Bones, Osseointegration, Bone resorption, Mice, 03 medical and health sciences, 0302 clinical medicine, bone regeneration, Osteogenesis, Transforming Growth Factor beta, In vivo, Animals, Osteopontin, Bone regeneration, General Dentistry, Cells, Cultured, Titanium, Osteoblasts, biology, Chemistry, Mesenchymal stem cell, osseointegration, Cell Differentiation, Articles, 030206 dentistry, 020601 biomedical engineering, In vitro, Cell biology, biology.protein, Original Article, Oral Surgery, bone allograft, bone resorption, Transforming growth factor
Abstract: Objectives Osteoblasts lay down new bone on implant surfaces. The underlying cellular mechanism and the spatio‐temporal mode of action, however, remain unclear. It can be proposed that growth factors released upon acidification by osteoclasts adsorb to the implant surface and control the early stages of osseointegration. Methods To simulate bone lysis by osteoclasts, titanium discs were exposed to acid bone lysate (ABL) followed by vigorous washing and seeding of oral fibroblasts. The expression of TGF‐β target genes interleukin 11 (IL11) and NADPH oxidase 4 (NOX4) was evaluated by reverse transcriptase polymerase chain reaction and IL11 ELISA. TGF‐β signaling activation was assessed via Smad2/3 immunofluorescence. The impact of ABL on osteogenic differentiation was determined with murine ST2 mesenchymal stromal cells. Results We report here that ABL‐conditioned titanium discs, independent of turned or rough surface, increased the expression of IL11 and NOX4. This increase was blocked by the TGF‐β receptor 1 antagonist SB431542. Further support for the TGF‐β signaling activation came from the translocation of Smad2/3 into the nucleus of oral fibroblasts. Moreover, titanium discs exposed to ABL decreased alkaline phosphatase and osteopontin in ST2 cells. Conclusions These in vitro findings suggest that titanium can adsorb TGF‐β from ABLs. The data provide a strong impetus for studies on the protein adsorption on implant surfaces in vitro and in vivo, specifically for growth factors including bone‐derived TGF‐β during successful and failed osseointegration.
Published: 2019
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44. DBBM shows no signs of resorption under inflammatory conditions. An experimental study in the mouse calvaria

Author: Ulrike, Kuchler, Gabriel Mulinari, Dos Santos, Patrick, Heimel, Alexandra, Stähli, Franz Josef, Strauss, Stefan, Tangl, and Reinhard, Gruber
Subjects: Disease Models, Animal, Mice, Inbred BALB C, Minerals, osteoclasts, Bone Regeneration, mice, calvaria, inflammation, bone substitutes, Skull, Animals, Cattle, Original Research
Abstract: Objectives Deproteinized bovine bone mineral (DBBM) is not resorbable. However, the behavior of DBBM under inflammatory conditions remains unclear. Aim of the study was therefore to evaluate the resorption of DBBM under local inflammatory conditions in vivo using the calvarial osteolysis model. Methods In thirty adult BALB/c mice, DBBM was implanted into the space between the elevated soft tissue and the calvarial bone. Inflammation was induced either by lipopolysaccharides (LPS) injection or by polyethylene particles (Ceridust) mixed with DBBM. Three modalities were randomly applied (n = 10 each): (a) DBBM alone (control), (b) DBBM + LPS, and (c) DBBM + polyethylene particles (Ceridust). Mice were euthanized on day fourteen, and each calvarium was subjected to histological and µCT analysis. Primary outcome was the size distribution of the DBBM particles. Secondary outcome was the surface erosion of the calvarial bone. Results Histological and µCT analysis revealed that the size distribution and the volume of DBBM particles in the augmented site were similar between DBBM alone and the combinations with LPS or polyethylene particles. Moreover, histological evaluation showed no signs of erosions of DBBM particles under inflammatory conditions. µCT analysis and histology further revealed that LPS and the polyethylene particles, but not the DBBM alone, caused severe erosions of the calvarial bone as indicated by large voids representing the massive compensatory new immature woven bone formation on the endosteal surface. Conclusions Local calvarial bone but not the DBBM particles undergo severe resorption and subsequent new bone formation under inflammatory conditions in a mouse model.
Published: 2018

45. Measurement of the W boson helicity fractions in the decays of top quark pairs to lepton + jets final states produced in pp collisions at s=8TeV

Author: Piergiulio Lenzi, Salvatore My, Andris Skuja, Sébastien Brochet, James Dolen, Ivica Puljak, Hans Reithler, Ben Bylsma, Freya Blekman, Ilse Krätschmer, David Michael Morse, G. Hamel de Monchenault, R. Lopes De Sá, Roberto Tenchini, Meng Xiao, Aditee Rane, Natalia Korneeva, Alexandre Léonard, Jacobo Konigsberg, Ettore Focardi, Jeannine Wagner-Kuhr, Vallary Bhopatkar, Josef Strauss, Guillaume Garcia, Maria Toms, John Michael Marraffino, E. De La Cruz-Burelo, S. Fonseca De Souza, Kenneth Call, Cesar Augusto Bernardes, Cosmin Dragoiu, Giuseppe Fasanella, Sung Keun Park, Jose M Hernandez, Y. Musienko, M. C. Fouz, Guillermo Breto, E. Eskut, James Keaveney, Matthew Chasco, Rachel Yohay, F. Simonetto, Sergio P Ratti, Deniz Poyraz, Kirti Ranjan, Carsten Hensel, M. Chamizo Llatas, Hans J. Vogel, Frank Chlebana, Constantin Heidegger, Paul Papacz, Bugra Bilin, Kati Lassila-Perini, Marco Esposito, Petra Merkel, Pelin Kurt, Kuntal Mondal, Giovanni Organtini, Sridhara Dasu, Emilio Meschi, W. T. Lin, Gianni Zumerle, Dylan Hsu, Mark Foerster, Sunil Bansal, P. M. Ribeiro Cipriano, Pierre Lecomte, Stefano Lacaprara, Raman Khurana, Paolo Spagnolo, P. Gras, Stefan Michael Heindl, W. Ji, Jorge Chaves, Si Xie, Nicholas Smith, Lindsey Gray, P. Martinez Ruiz del Arbol, Emanuela Barberis, Avraham Yagil, Nicolo Magini, Michael Dittmar, R. Kunnawalkam Elayavalli, Steven Kaplan, J. A. Brochero Cifuentes, Aleksandar Aleksandrov, Frank Raupach, Jacob Linacre, Bernard Ille, Robert Stone, Frank Meier, Ali Mohammadi, Christian Hartl, Dinko Ferencek, Giovanni Franzoni, Evrim Ersin Kangal, Ashok Kumar, Krishna Thapa, M. Miñano Moya, E. Belchior Batista Das Chagas, Jean-Charles Fontaine, Anton Dimitrov, Anne Dabrowski, Tulika Bose, Vladimir Cherepanov, Andrea Gozzelino, Wuming Luo, P. Rebello Teles, Amandeep Kaur Kalsi, Leonard Spiegel, Alexandros Attikis, Francesco Romeo, Robert Klanner, Alberto Belloni, Paolo Giacomelli, Werner Lustermann, Andromachi Tsirou, Tatiana Medvedeva, Camille Beluffi, Batool Safarzadeh, Maria Hempel, Darin Acosta, Youngkwon Jo, Kristian Allan Hahn, R. Placakyte, Bradley Cox, Filip Thyssen, Piet Verwilligen, Evgueni Vlasov, Attilio Santocchia, Jeson Jacob, Karl Gill, Daniele Bonacorsi, Y. J. Lu, Hasan Ogul, Daniel Duggan, Loic Quertenmont, Aram Apyan, Jean Fay, Abideh Jafari, Nathan Mirman, Burak Bilki, Nicolò Trevisani, Yacine Haddad, Matti J Kortelainen, Yang Yang, Juan Garcia-Ferrero, Alexei Raspereza, David J. Smith, Gianluca Cerminara, Maxim Perfilov, S. Sanchez Cruz, Dooyeon Gyun, John Perry Cumalat, Swagata Mukherjee, R. Bi, Supratik Mukhopadhyay, Gregor Kasieczka, Y. Chao, Alexandre Zabi, Lesya Shchutska, Andrea Massironi, Ricardo Lopez-Fernandez, Anne-Laure Pequegnot, Edmund Berry, Marco Verzocchi, Steffen Röcker, Fanbo Meng, Caroline Collard, Giuseppe Barbagli, Salvatore Nuzzo, Dominick Olivito, S. Roy Chowdhury, Colin Jessop, Philip H Butler, M. Calderon De La Barca Sanchez, L. Alunni Solestizi, Tariq Aziz, Dave M Newbold, Adel Terkulov, Caglar Zorbilmez, Emrah Tiras, Toyoko Orimoto, D. W. Kim, Georgios Anagnostou, Melody A. Swartz, Maxwell Chertok, Danek Kotlinski, Simone Gelli, Vladimir Rekovic, Inkyu Park, H. Wei, S. Bilmis, C. De Oliveira Martins, Victor Golovtsov, Pushpalatha C Bhat, Sh. Jain, Grant Riley, Robert Fischer, Davide Cieri, Troy Mulholland, James Castle, Seungkyu Ha, F. L. Fabbri, Daniele Fasanella, Bolek Wyslouch, Qian Wang, A. Melo, Matthias Kasemann, Giovanni Polese, Marko Dragicevic, Alexander Toropin, N. Zaganidis, A. Mott, Cecilia Elena Gerber, Maria Spiropulu, Denis Gelé, Chang-Seong Moon, Mauro Emanuele Dinardo, Sven Dildick, Charles Welke, Nhan Viet Tran, Paola Salvini, Lorenzo Bianchini, Svenja Schumann, Samuel Bein, Rami Kamalieddin, D. Sunar Cerci, Oliver Gutsche, Matthew Herndon, Alessio Bonato, Christof Roland, David Colling, Jennifer Poehlsen, L. Gauthier, Marcos Fernandez, Florian Beaudette, Terence Libeiro, Karim Damun Trippkewitz, Maksym Titov, Daniel Klein, Herbert Rohringer, Federico Ferri, Douglas Berry, M. A. B. Ali, Andrew Kubik, Daniel Arcaro, Marek Walczak, Amina Zghiche, Brendan Diamond, Igor Azhgirey, Salvatore Buontempo, Frank Golf, Andrew Gilbert, Ridhi Chawla, Francesco Navarria, Andrey Popov, Christian Sander, Giulia D'imperio, Jovan Milosevic, Jia Fu Low, Darren Puigh, Shalhout Shalhout, Y. Choi, Brandon Allen, Mauro Menichelli, Luca Perniè, Roland Horisberger, Vitaliano Ciulli, Apostolos Panagiotou, Benjamin Kilminster, Andreas Pfeiffer, Kreso Kadija, Aniello Spiezia, Christopher West, Gregor Mittag, Georgios Mavromanolakis, Michele Arneodo, S. Tkaczyk, David Stuart, Alice Mignerey, Evgenii Tarkovskii, Ana Ovcharova, Anna Julia Zsigmond, Christopher Anelli, Meenakshi Narain, Mirena Ivova Paneva, Dustin Burns, Nishu Nishu, Peter Robmann, Alexey Finkel, Brieuc Francois, Nikolai Shumeiko, Ibrahim Soner Zorbakir, Bora Akgun, Andrea Venturi, M. Khakzad, Rino Castaldi, V. Bunichev, Benjamin Michlin, Alessandro Thea, Isabel Pedraza, Sunil Somalwar, Paolo Azzurri, Emilien Chapon, Urs Langenegger, Martino Dall'Osso, Michael Buttignol, Robert Hirosky, Zhoudunming Tu, Isabel Ojalvo, Mariarosaria D'Alfonso, Mario Galanti, F. Mohamad Idris, Lukas Vanelderen, Youn Roh, Christopher George Tully, Gobinda Majumder, Alexander Belyaev, Y. F. Liu, Igor Miagkov, P. Verdier, Marino Missiroli, C. Barth, Andrius Juodagalvis, Michael Krohn, Jeremie Alexandre Merlin, Piotr Zalewski, Hyunyong Kim, Mihee Jo, Kirill Skovpen, A. Malta Rodrigues, Markus Stoye, Kai Yi, Zoltan Szillasi, Andrzej Zuranski, K. Krajczar, L. J. Gutay, David Curry, Chayanit Asawatangtrakuldee, Yetkin Yilmaz, Vladimir Epshteyn, Paul Geffert, Luigi Guiducci, Gregory R Snow, Jared Turkewitz, Adrian Perieanu, A. Meyer, Russell Richard Betts, Vittorio Raoul Tavolaro, Maria Agnese Ciocci, Adrian Byszuk, Andreas Psallidas, C. Vander Velde, Tiziano Camporesi, L. Brigliadori, Patrick Dunne, Seema Sharma, Gian Michele Innocenti, A. Ranieri, Livia Soffi, Christopher Seez, Ada Solano, Barry Blumenfeld, Louise Skinnari, Nural Akchurin, Igor Volobouev, F. Rezaei Hosseinabadi, Brian Dorney, Crisostomo Sciacca, Andrey Uzunian, Maxim Goncharov, Martina Machet, C. Wissing, E. Carrera Jarrin, Douglas Wright, Andreas Hinzmann, Christopher Palmer, Marcin Konecki, Claudio Campagnari, Conor Henderson, Alain Givernaud, Jane Nachtman, R. Gonzalez Suarez, Annika Vanhoefer, Alice Bean, Balazs Ujvari, Rishi Patel, Y. D. Oh, Prasenjit Mal, Joseph Goodell, Stephanie Brandt, Stephen Sanders, R. Mankel, Fabrizio Palla, Marco Pieri, David Fehling, Wolfgang Lohmann, Joonas Talvitie, Ian R Tomalin, S. Afanasiev, Artur Lobanov, Nathaniel Pastika, Ioannis Evangelou, Xinmei Niu, P. Van Hove, Alice Cocoros, Christina Snyder, Konstantin Matchev, J. J. Hollar, Jean-Marie Brom, M. Y. Choi, Jennifer Chu, J. H. Kim, Luca Martini, Igor Bayshev, Aaron Levine, Xavier Coubez, David Sperka, Gaelle Boudoul, Anita Topkar, Agnieszka Zagozdzinska, Elvire Bouvier, Alexis Kalogeropoulos, Sergio F Novaes, Stephen Mrenna, A. Pérez-Calero Yzquierdo, Giuseppe Iaselli, Olga Evdokimov, Junghwan Goh, Livio Fanò, W. 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Ruiz Alvarez, Georg Sieber, Viesturs Veckalns, Igor Golutvin, Mircho Rodozov, Dario Bisello, Pascal Paganini, Maria Florencia Canelli, Fabrizio Ferro, Thomas Ferbel, Dan Green, R. Walsh, Lars Sonnenschein, Luca Scodellaro, S. Schael, Maria Cepeda, Jennifer Ngadiuba, Thomas Schoerner-Sadenius, Nicola Bacchetta, Marta Ruspa, Stepan Obraztsov, Anshul Kapoor, Evaldas Juska, C. Neu, Jorgen D'Hondt, Davide Piccolo, Attila Racz, Roberta Arcidiacono, Jonathan Fulcher, Anatoli Pashenkov, Avto Kharchilava, Mikhail Ignatenko, Jelena Luetic, Tapio Lampén, Roberto Sacchi, Bahareh Roozbahani, Nadeesha Wickramage, Anna Zanetti, Q. Ingram, Norraphat Srimanobhas, Dermot Moran, Natascha Hörmann, Tejinder Virdee, Nicolò Tosi, M. Jones, Camilla Galloni, Seth Conrad Zenz, I. Heredia-De La Cruz, Paul Avery, Salavat Abdullin, Lisa Benato, Andrew Godshalk, Vincenzo Daponte, Federica Primavera, M. Vidal Marono, Daniele Marconi, S. De Visscher, W. 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Olmedo Negrete, Jasper Lauwers, Wajid Ali Khan, Inna Kucher, Aysen Tatarinov, Ping Tan, Ivan Asin, Stefano Colafranceschi, C. Scharf, Siarhei Shulha, Sarah Beranek, Tuure Tuuva, Elizabeth Kennedy, Margaret Zientek, Unki Yang, Ozgun Kara, G. Nicolas Kaufman, Daniel Gastler, D. J. Lange, Seth Moortgat, Paolo Gunnellini, Juliet Ritchie Patterson, Joao Varela, Leander Litov, Joshy George, Jean-Pierre Merlo, P. Sphicas, Anindya Roy, Muhammad Waqas, Predrag Milenovic, Peter R Hobson, Rocky Bala Garg, Julie Malcles, Joanne Cole, Myung-kwan Ryu, Lucia Perrini, Patrick Connor, E. Eskandari Tadavani, Byounghoon Lee, Giovanna Selvaggi, Sudarshan Paramesvaran, Victor Daniel Elvira, Daniel Abercrombie, Bilal Kiani, Stephane Cooperstein, S. Ragazzi, Gabor Istvan Veres, Alexandre Mertens, Sarah Catherine Eno, Jan-Frederik Schulte, D. Benedetti, Hugues Brun, Pieter Everaerts, J. Y. Han, Titas Roy, Alexx Perloff, Roberto Carlin, J. F. Tsai, Pierre Depasse, Vyacheslav Klyukhin, M. Van De Klundert, Sören Erdweg, Chris Lucas, Richard B. Lipton, Mustafa Numan Bakirci, Dustin Stolp, Lorenzo Viliani, Kurt Jung, Kristian Harder, P. Bloch, Josh Kaisen, Stefan Wayand, Alajos Makovec, Scott Wilbur, D. Cutts, Michael Benjamin Andrews, Simone Paoletti, Rebecca Lane, Suchandra Dutta, Anne-Marie Magnan, Wagner Carvalho, S. C. Kao, Greg Landsberg, Cécile Caillol, Manjit Kaur, Anna Colaleo, J. Rodrigues Antunes, Francesco Fiori, Pedrame Bargassa, Nikolay Voytishin, Kira Burt, Thomas Peiffer, A. Baden, Gino Bolla, Rylan Conway, J. F. de Trocóniz, Matthias Ulrich Mozer, Massimiliano Chiorboli, A. Morelos Pineda, Johannes Brandstetter, S. B. Oh, Alexander Malakhov, Efe Yazgan, Günter Flügge, Qiao Xu, M. Naimuddin, Tyler Ruggles, Robert Clare, Patrizia Azzi, Thomas Müller, Thomas Hebbeker, Paul Lecoq, M. Dordevic, A. De Roeck, Ian Michael Nugent, A. J. Campbell, A. David, Ksenia Shchelina, Albert M. Sirunyan, Timo Peltola, Michael Schmitt, Carlo Rovelli, Silvio Donato, Ezio Torassa, Carlotta Favaro, Harry Cheung, Andrew Johnson, Peter Schleper, Zhen Hu, Keith Ulmer, A. De Wit, Frans Meijers, Severiano Carpinteyro, Zoltan Laszlo Trocsanyi, J. Conway, D. Del Re, Vincent Lemaitre, P. Kyberd, Paul Baillon, D. Winn, Artur Apresyan, Marc Besancon, Dinyar Rabady, Bibhuti Parida, Wolfram Dietrich Zeuner, Sergey Rusakov, David Futyan, Malgorzata Kazana, Guido Tonelli, Zeljko Antunovic, Claudia-Elisabeth Wulz, Christoph Paus, and Wolfgang Waltenberger
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Higher education, 010308 nuclear & particles physics, business.industry, European research, Library science, 01 natural sciences, 0103 physical sciences, media_common.cataloged_instance, Christian ministry, Science policy, European union, 010306 general physics, business, media_common
Abstract: Individuals have received support from the Marie-Curie pro-gramme and the European Research Council and EPLANET (Euro-pean Union); the Leventis Foundation; the Alfred P. Sloan Founda-tion; the Alexander von Humboldt Foundation; the Belgian Fed-eral Science Policy Office; the Fonds pour la Formation a la Recherche dans l’Industrie et dans l’Agriculture (FRIA-Belgium); the Agentschap voor Innovatie door Wetenschap en Technologie (IWT-Belgium); the Ministry of Education, Youth and Sports (MEYS) of the Czech Republic; the Council of Science and Industrial Re-search, India; the HOMING PLUS programme of the Foundation for Polish Science, cofinanced from European Union, Regional De-velopment Fund; the Mobility Plus programme of the Ministry of Science and Higher Education (Poland); the OPUS programme of the National Science Center (Poland); the Thalis and Aris-teia programmes cofinanced by EU-ESF and the Greek NSRF; the National Priorities Research Program by Qatar National Research Fund; the Programa Clarin-COFUND del Principado de Asturias; the Rachadapisek Sompot Fund for Postdoctoral Fellowship, Chu-lalongkorn University (Thailand); the Chulalongkorn Academic into Its 2nd Century Project Advancement Project (Thailand); and the Welch Foundation, contract C-184
Published: 2016

46. Search for a light charged Higgs boson decaying to c s ¯ $$ \mathrm{c}\overline{\mathrm{s}} $$ in pp collisions at s = 8 $$ \sqrt{s}=8 $$ TeV

Author: Viktor Veszpremi, Abdulla Abdulsalam, Gianluca Petrillo, Matthias Schröder, Maria Hempel, Min Sang Ryu, Shabnam Jabeen, Andrea Perrotta, Hyunchul Kim, Dmytro Kovalskyi, Gyorgy Vesztergombi, Luca Malgeri, Frank Jm Geurts, Tom Cornelis, Shivali Malhotra, Gunter Quast, Ennio Monteil, Aldo Penzo, Natalie Heracleous, Kisoo Lee, Lalit Mohan Pant, Inga Bucinskaite, H. S. Chen, Fuqiang Wang, Justin Pilot, Gian Mario Bilei, Metin Ata, Petr Moisenz, David Ja Cockerill, Wolfgang Lange, Gianni Masetti, Erik Gottschalk, Andrea Delgado, Duncan Leggat, Yuriy Pakhotin, Joseph Goodell, Florian Scheuch, Boaz Klima, Manqi Ruan, Pedro Silva, Regina Demina, Nitish Dhingra, Sourabh Dube, Matthew Walker, Wolfgang Funk, Stephen Sanders, Wesley H Smith, James Faulkner, Joosep Pata, Colin Bernet, Nadia Pastrone, Salvatore Di Guida, Grzegorz Brona, Arun Luthra, James Hirschauer, Jordon Rowe Adams, Kristian Harder, Richard G Kellogg, Michael Tytgat, David Lange, Robin Erbacher, Senta Greene, Sergey Shmatov, Douglas Rank, Andreas Hinzmann, Sarah Kate Boutle, Maciej Górski, Anna Kropivnitskaya, Aaron Dominguez, Abdollah Mohammadi, Kalanand Mishra, Walter Luiz Aldá Júnior, Felicitas Pauss, Celso Martinez Rivero, Ayse Polatoz, Marcin Konecki, Artur Lobanov, Nathaniel Pastika, Andras Hazi, Antonio Delgado Peris, Alberto Santoro, Monika Grothe, Grigory Safronov, Austin Baty, Ulascan Sarica, Ryo Yonamine, Nicholas Mucia, Xiaohang Quan, Emanuele Usai, Roberto Rossin, Vladimir Petrov, Thomas N. Williams, Josh Kaisen, Himali Kalakhety, Yeng-Ming Tzeng, Matthieu Marionneau, Arne-Rasmus Draeger, Mehmet Zeyrek, Boris Mangano, Martti Raidal, Emmanuel Contreras-Campana, Pamela Klabbers, Ian Anderson, Burin Asavapibhop, Aram Avetisyan, Stefan Wayand, Scott Wilbur, Michael Benjamin Andrews, Simone Paoletti, Rebecca Lane, Natale Demaria, Verena Martinez Outschoorn, Nil Valls, Eric Wayne Vaandering, Ioannis Evangelou, David Romero Abad, Seth Cooper, Alexandre Sakharov, Susan Gascon, Sanjay Arora, Gunther Roland, Yue Shi Lai, Sara Alderweireldt, Olena Karacheban, Arnaud Pin, Cristóvão Beirão Da Cruz E Silva, Lea Caminada, Rong-Shyang Lu, Luigi Benussi, Gouranga Kole, Matthias Geisler, Irving Daniel Sandoval Gonzalez, Stefan Gundacker, Rafael Marco, Sanmay Ganguly, Simon Regnard, Leonid Levchuk, Ravi Janjam, Anton Karneyeu, Leonard Apanasevich, Dave M. Newbold, Alexey Svyatkovskiy, Luca Scodellaro, Maria Cepeda, Jochen Schieck, Jorgen D'Hondt, Vincenzo Chiochia, Nadeesha Wickramage, Anna Zanetti, Eleni Petrakou, Charalambos Nicolaou, Salvatore Buontempo, Paul Avery, Salavat Abdullin, Lisa Benato, Isabelle De Bruyn, Quentin Python, Alexander Ershov, Fan Xia, Dietrich Liko, Jesse Heilman, Mykhailo Dalchenko, Ajit Kumar Mohanty, U. Nauenberg, Riccardo Andrea Manzoni, Christian Veelken, Markus Klute, Joel Goldstein, Luigi Calligaris, Kevin Pedro, Tiehui Liu, Martin Görner, Silvano Tosi, Maxime Guilbaud, Daniel Treille, D. De Jesus Damiao, Babak Rahbaran, Edmilson José Tonelli Manganote, German Martinez, Giannis Flouris, Cristina Botta, Mai El Sawy, Guido Tonelli, Zeljko Antunovic, Claudia-Elisabeth Wulz, Christoph Paus, Wolfgang Waltenberger, Piergiulio Lenzi, Arthur Moraes, Hui Li, Salvatore My, James Dolen, Marco-Andrea Buchmann, Freya Blekman, Ilse Krätschmer, David Michael Morse, Kai-Feng Chen, Ettore Focardi, Jeannine Wagner-Kuhr, Vallary Bhopatkar, John Rander, Josef Strauss, John Michael Marraffino, Konstantinos Petridis, Kenneth Call, Cesar Augusto Bernardes, Aniello Spiezia, Cosmin Dragoiu, Ajit Mohapatra, Deniz Poyraz, Stephane Perries, Carsten Heidemann, Costas Foudas, Rebeca Gonzalez Suarez, Devdatta Majumder, Dominique Gigi, Peter Kreuzer, Benoit Courbon, Raffaello D'Alessandro, Slawek Tkaczyk, Andrei Sobol, William Ferguson, Aytul Adiguzel, Gui Nyun Kim, Claudia Pistone, Wolfgang Adam, Pierre Van Hove, Andreas Kornmayer, Marc Dünser, Matthias Endres, Marcos Cerrada, Magdalena Malek, Norbert Tambe, David Nash, R. Stringer, Philip Lawson, Mark Grimes, Mark Baber, Thomas Esch, Vladimir Popov, Otman Charaf, Simon Knutzen, Jacopo Pazzini, Cecilia Elena Gerber, Gian Michele Innocenti, Livia Soffi, Christopher Seez, Ada Solano, Gaetano-Marco Dallavalle, Jose F Benitez, Salvatore Costa, Indara Suarez, Yong Ban, Tariq Aziz, Ajeeta Khatiwada, Ketino Kaadze, Gala Nicolas Kaufman, Marko Dragicevic, Christian Contreras-Campana, Willard Johns, Leonardo Benucci, André Holzner, Werner Sun, Joschka Lingemann, Nicholas Cripps, Faridah Mohamad Idris, Emmanuel Olaiya, Alexander Schmidt, Nadir Daci, David Sheffield, Mohsen Khakzad, Andre David Tinoco Mendes, Roberto Dell'Orso, Christopher Clarke, Sergey Troshin, David D'Enterria, Thomas Bergauer, Helio Nogima, Elif Asli Yetkin, Michael Planer, Alberto Orso Maria Iorio, Felice Pantaleo, Niladribihari Sahoo, Apichart Hortiangtham, Dezso Horvath, Luisa Alunni Solestizi, Ryan Mueller, Alessia Tricomi, Krzysztof Nawrocki, Nikolay Tyurin, Alberto Hernandez-Almada, Roumyana Hadjiiska, Igor Smirnov, Jaakko Härkönen, Vladimir Mossolov, Alexey Baskakov, Georg Auzinger, Antonio Morelos Pineda, Ganna Dolinska, Harvey B Newman, Jeffrey Berryhill, Melike Akbiyik, Eike Schlieckau, Sarmad Masood Shaheen, Ludivine Ceard, Jessica Leonard, Daniele Bonacorsi, Ayman Mahrous, Robyn Lucas, Ricardo Lopez-Fernandez, Albert Knutsson, Suchandra Dutta, Anne-Marie Magnan, Wagner Carvalho, S. C. Kao, Greg Landsberg, Cécile Caillol, Giuseppe Della Ricca, Sw. Banerjee, Manjit Kaur, Fan Yang, Francesco Fiori, Philippe Busson, Pedrame Bargassa, Joseph Bochenek, Kira Burt, Thomas Peiffer, Paul Dauncey, Damir Lelas, Olga Driga, Javier Duarte, Suvankar Roy Chowdhury, Alexey Vorobyev, Stefano Colafranceschi, Jean-Baptiste Sauvan, Gigi Rolandi, Siarhei Shulha, Paolo Gunnellini, Michael Mooney, Batool Safarzadeh, Justin Hugon, Juliet Ritchie Patterson, Stefano Argiro, Alexey Ferapontov, Joao Varela, Lucia Masetti, Leander Litov, Kyong Sei Lee, Catherine Newman-Holmes, Michele De Gruttola, Jean-Pierre Merlo, Michael Sigamani, Rocky Bala Garg, Zhenbin Wu, Bhawna Gomber, Marcello Mannelli, Marco Musich, Dominick Olivito, Colin Jessop, Manuel Olmedo Negrete, Anne-Laure Pequegnot, Edmund Berry, Richard Vidal, Matthias Kasemann, Paola Salvini, Caglar Zorbilmez, Emrah Tiras, Toyoko Orimoto, Luciano Romero, Bolek Wyslouch, Paolo Giacomelli, Valerio Calvelli, Francisca Javiela Munoz Sanchez, Maria Spiropulu, Shin-Shan Yu, Geoffrey Hall, Sanjay Padhi, Amparo Lopez Virto, Matthew Nguyen, Esa Tuovinen, Pedro G Mercadante, Hans-Christian Kaestli, Wee Don Teo, Panagiotis Kokkas, Niels Dupont, Sarah Malik, Edward Laird, Aurore Savoy-Navarro, Pierluigi Paolucci, Luca Mastrolorenzo, Zuhal Seyma Demiroglu, Vieri Candelise, Lana Beck, Samantha Dooling, Daniel Meister, Thomas Strebler, Ted Kolberg, Marc Osherson, Matteo Centis Vignali, Yossof Eshaq, Muhammad Shoaib, Claude Charlot, Burton Betchart, Reddy Pratap Gandrajula, Kadri Ozdemir, Heriberto Castilla-Valdez, Adam Dishaw, Claudia Seitz, U. Tamponi, Linda Finco, Alfredo Castaneda Hernandez, Keith Rose, Mingshui Chen, Nikita Beliy, Matthias Komm, Scott Thomas, Piero Giorgio Verdini, Matevz Tadel, Viola Sordini, Niki Saoulidou, Sercan Sen, Y. H. Chang, Zhenyu Chen, Geoffrey Smith, Jeremy Scott Werner, Shalhout Shalhout, Christopher Silkworth, Nishu Nishu, Urs Langenegger, Martino Dall'Osso, Michael Buttignol, Adrian Byszuk, Kittikul Kovitanggoon, Brian Dorney, Sanjeev Kumar, Crisostomo Sciacca, Nicholas Eggert, Maxim Goncharov, Richard D Field, Marco Pieri, Francesco Costanza, David Fehling, Ian R Tomalin, David Saltzberg, José David Ruiz Alvarez, Vladimir Cherepanov, Axel König, Andrei Gritsan, Davide Cieri, Shimaa Abu Zeid, Giovanni Polese, Rami Kamalieddin, Yu-Wei Chang, David Silvers, Christian Sander, Jorge F de Trocóniz, Guillaume Garcia, Joanne Cole, Eija Tuominen, Luigi Fiore, Lucia Perrini, Roberval Walsh, D. M. Strom, Matthew Herndon, Alessio Bonato, Alexey Kamenev, Fabio Cossutti, Brendan Diamond, Giulia D'imperio, Sandro Gonzi, Jovan Milosevic, Mareike Meyer, Darren Puigh, Vitaliano Ciulli, Leonardo Di Matteo, Apostolos Panagiotou, Benjamin Kilminster, Christopher West, Hasan Ogul, Daniel Duggan, Loic Quertenmont, Aram Apyan, David Petyt, Dan Knowlton, Xin Shi, Hans Rykaczewski, Kerstin Hoepfner, Eirini Tziaferi, Richard Loveless, Serguei Afanasiev, Zhaoxia Meng, Chiara Mariotti, Robert M Harris, Elliot Hughes, Charles C. Richardson, Daniele Spiga, Houmani El Mamouni, Piotr Traczyk, David Jonathan Hofman, Ihar Marfin, Andrea Castro, Stanislav Lisniak, Aidan Randle-Conde, Mikhail Gavrilenko, Juska Pekkanen, Nicholas Wardle, Randy Ruchti, Joe Incandela, Erika Garutti, Hannes Schettler, Giancarlo Mantovani, Carlo Battilana, Charles Ferraioli, Pooja Saxena, M. Park, Luca Cadamuro, Virginia Azzolini, Giacomo Bruno, Manuel Calderon De La Barca Sanchez, Tomas Hreus, Rainer Mankel, Eric Christian Chabert, Sean Flowers, Sandeep Bhowmik, Thiago Tomei, Kirti Ranjan, Milos Dordevic, Carsten Hensel, Mihee Jo, Hannes Sakulin, A. York, Arnd Meyer, Gabriella Pugliese, Vladimir Palichik, Sue Ann Koay, Albert De Roeck, Atanu Modak, Dario Bisello, Pascal Paganini, Giovanna Selvaggi, Heiko Geenen, Jiyeon Han, Ward Van Driessche, Bastian Kargoll, A. Christian, Gagan Bihari Mohanty, Gabor Istvan Veres, Alexandre Mertens, Marcos Fernandez, Young-Il Choi, Sarah Catherine Eno, J William Gary, Florian Beaudette, Andrew Kubik, Marek Walczak, Marcella Diemoz, Marco Cardaci, Nikolai Shumeiko, Saeid Paktinat Mehdiabadi, Peter Elmer, Christian Böser, Robert Hirosky, Si-Jin Qian, Isabel Ojalvo, Youn Roh, Barry Blumenfeld, Rebekka Sophie Höing, Wanda Lucia Prado Da Silva, Matthew Chasco, Rachel Yohay, Takashi Matsushita, Benjamin Michlin, Anita Topkar, F. Simonetto, Claus Kleinwort, Alexander Savin, Catherine Vander Velde, Caleb Fangmeier, Quentin Ingram, Maryam Zeinali, Patrick Jarry, Tilman Rohe, Benjamin Charles Radburn-Smith, Igor Vorobiev, Josef Hammer, Alexey Volkov, Isa Dumanoglu, Sam Daniel Mullin, Giacomo Sguazzoni, Alan Campbell, Alessio Boletti, Matteo Marone, Jie Zhang, Pushpalatha C Bhat, Lucas Brito, Panos A Razis, Steven R. 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Ford, Christian Autermann, Can You, Kenneth Bloom, Federico Preiato, Oleg Prokofyev, Wolfram Erdmann, Nicolo Cartiglia, Rajat Gupta, Mara Senghi Soares, Serguei Ganjour, Silvia Taroni, Thomas Perry, Lamia Benhabib, Gordon H. Hanson, Michel Della Negra, Geonmo Ryu, Pramod Lamichhane, Sandhya Jain, Subir Sarkar, Andrey Ostapchuk, Marcus Hohlmann, Hannes Neugebauer, Carlos Florez, Juan Alcaraz Maestre, Ahmad Borzou, Chiara La Licata, John Stupak, Raffaele Gerosa, Huaqiao Zhang, Alexander Ledovskoy, Vincent J Smith, Yuri Andreev, Petra Van Mulders, Jian-Guo Bian, Giuseppe Broccolo, Andrey Pozdnyakov, Thomas Kress, Raphael Granier de Cassagnac, Darien Wood, Jyothsna Rani Komaragiri, Satyaki Bhattacharya, Eric Takasugi, Isabell-Alissandra Melzer-Pellmann, Nicholas John Hadley, Mark Turner, Jehad Mousa, Troy Mulholland, Christian Barth, Daniele Fasanella, Karl Matthew Ecklund, Jennifer S. Haas, Jennifer Poehlsen, Paul Kyberd, Maral Alyari, Giuseppe Bagliesi, Anna Julia Zsigmond, Andrea Venturi, Ta-Wei Wang, Songkyo Lee, Piet Verwilligen, Stefan Spanier, Mariarosaria D'Alfonso, Mario Galanti, Zoltan Szillasi, Alexander Gude, Joao Rodrigues Antunes, Andrey Uzunian, Christopher Palmer, Annika Vanhoefer, Alice Bean, Balazs Ujvari, Yuri Musienko, Aaron Levine, Manuel Franco Sevilla, Shervin Nourbakhsh, Jian Sun, Artur Kalinowski, Qiang Li, Nabarun Dev, Viacheslav Bunichev, Marion Murumaa, Thomas Lenzi, Min Suk Kim, Frank Hartmann, Luciano Orsini, Luca Pacher, Vasile Mihai Ghete, Claire Shepherd-Themistocleous, Antonis Agapitos, Thi Hien Doan, Benoit Roland, Daniel Denegri, Hartmut Stadie, James Zabel, Sebastian Thüer, Nikoloz Skhirtladze, Alexandre Aubin, Azeddine Kasmi, Giuseppe Codispoti, Pavel Sorokin, Narumon Suwonjandee, Christopher Bruner, Andrew Carnes, Jordan Tucker, Teimuraz Lomtadze, Claudio Caputo, Alberto Sánchez Hernández, Pasquale Musella, Andrea Bocci, Tommaso Dorigo, Alexis Descroix, Sandra Malvezzi, Pietro Faccioli, Hamit Mermerkaya, Alberto Zucchetta, Jose Lazo-Flores, Maria Chamizo Llatas, Juan Pablo Gomez, Ivan Reid, Anastasia Grebenyuk, Ijaz Ahmed, Dmitry Hits, Jorma Tuominiemi, Maria Cruz Fouz, Imad Baptiste Laktineh, Joseph Lykken, Lucas Taylor, Matthew Citron, Marco Cuffiani, Oliver Buchmuller, Chunjie Wang, Karl Gill, Antonio Ranieri, Mauro Menichelli, Luca Perniè, Roland Horisberger, Yuan Chao, Georgios Mavromanolakis, Michele Arneodo, Christopher Anelli, Paul Edmund Karchin, Akram Khan, Nicolas Chanon, Helena Malbouisson, Alex J. Barker, Camelia Mironov, Ying Lu, Javier Andres Brochero Cifuentes, Benedikt Vormwald, James Alexander, Ilknur Hos, J. N. Butler, Fabiola Vazquez Valencia, Genius Walia, Lukasz Kreczko, P. Squillacioti, Byung-Sik Hong, Paolo Lariccia, Rudolf Fruehwirth, Stefano Casasso, Michael Hildreth, Oscar Gonzalez Lopez, Nick Van Remortel, Shannon Crucy, Tanmay Sarkar, Rosamaria Venditti, Jessica Brinson, Stefan Piperov, Florian Zenoni, John Strologas, Charles Maguire, Theodoros Geralis, Andrea Rizzi, Amr Radi, Bożena Boimska, Kerem Cankocak, Clemens Wöhrmann, Michal Simon, Harrison Prosper, Carley De Oliveira Martins, Stephen Robert Wagner, Sanghyeon Song, Yeonju Go, Nikolay Terentyev, Christophe Ochando, Amnon Harel, Joram Berger, Francesco Santanastasio, Stoyan Stoynev, Tongguang Cheng, Simon Fink, Sergo Jindariani, Enrique Calvo, John Bradmiller-Feld, Rino Castaldi, John Hakala, Alexander Bylinkin, Bhawandeep Bhawandeep, Young Ho Shin, Sourav Dey, Daniel Teyssier, John Yelton, Victor Perelygin, Alessandra Fanfani, Katharina Bierwagen, Marcos Correa Martins Junior, Alexander Dierlamm, Andrew Askew, Gurpreet Singh, Styliani Orfanelli, Jasper Lauwers, Zheng Wang, Wajid Ali Khan, Aysen Tatarinov, Ping Tan, Ivan Asin, Michal Szleper, Philippe Gras, Roberto Chierici, Chia-Ming Kuo, Sarah Beranek, Tuure Tuuva, Elizabeth Kennedy, L. Demortier, Candan Dozen, Sangeun Lee, Michael Wayne Arenton, Ramkrishna Sharma, Daniel Gastler, Alain Givernaud, Carmen Diez Pardos, Predrag Milenovic, Sean Kalafut, Peter R Hobson, Mirena Ivova Paneva, James John Brooke, Stefka Stoykova, Byounghoon Lee, Sudarshan Paramesvaran, Victor Daniel Elvira, Bilal Kiani, Alexander Snigirev, Fabrizio Gasparini, Michele Selvaggi, Gulsen Onengut, Viktor Matveev, Clemens Lange, Philippe Miné, Santiago Folgueras, George Alverson, Roman Kogler, Satoshi Hasegawa, Benjamin Kreis, Mark Pesaresi, Analu Custódio, Markus Seidel, Vineet Kumar, Gregor Mittag, Jennifer Chu, Luca Martini, Viktor Khristenko, Umesh Joshi, Simon Spannagel, Doris Eckstein, Achim Geiser, Javier Cuevas, Torsten Dahms, Marcello Abbrescia, Danila Tlisov, Francesco Pandolfi, Andres Tiko, Milena Quittnat, Federica Fanzago, Ferdinando Giordano, Viktor Konoplyanikov, Paul Sheldon, Yuichi Kubota, Gilles De Lentdecker, Adrian Perieanu, Russell Richard Betts, Conor Henderson, Christina Snyder, Konstantin Matchev, Jean-Marie Brom, Xavier Coubez, Fabrice Couderc, Alex Garabedian, Egidio Longo, Francesca Ricci-Tam, Federico De Guio, Ivan Marchesini, Vishwajeet Jha, Salvatore Rappoccio, Loukas Gouskos, Maksim Azarkin, Antonio Vilela Pereira, Ivo Nicolas Naranjo, Xavier Janssen, Ken W Bell, Dirk Ryckbosch, Iban Jose Cabrillo, Gian Piero Siroli, Metin Yalvac, Stephan Lammel, Daniel Noonan, Salim Cerci, Olaf Behnke, Giuseppe Antonio Pierro, Evgueni Vlasov, Enrico Robutti, Kurtis F Johnson, Merijn Van De Klundert, Greg P Heath, Jian Wang, Alexey Kalinin, Maxime Gouzevitch, Iasonas Topsis-Giotis, Alexander Toropin, Jesus Puerta Pelayo, Virgil E Barnes, Marko Ekmedzic, T. J. Pearson, Alessio Ghezzi, Johannes Haller, Vadim Oreshkin, Fabio Ravera, Marco Bellato, Nikola Godinovic, Hualin Mei, Altan Cakir, Paolo Meridiani, Tomislav Seva, Aron Soha, Ewerton Belchior Batista Das Chagas, Amithabh Shrinivas, Christoph Schäfer, Christoph Grab, Henning Kirschenmann, Edouard Boos, Yueh-Feng Liu, Peter Thomassen, Adrián Quintario Olmeda, Phillip Russell Dudero, Philipp Eller, Lev Uvarov, Rajdeep Mohan Chatterjee, Stilianos Kesisoglou, Rocio Vilar Cortabitarte, Duncan Ralph, Wim De Boer, Tiziano Rovelli, Michal Bluj, Giuseppe Lanza, Andrey Marinov, Tomasz Frueboes, Nicola De Filippis, Alberto Ruiz-Jimeno, Matthias Edelhoff, Robert Cousins, Didar Dobur, Chi Lin, Nicole Ruckstuhl, Austin Ball, Nathaniel Odell, Juan Suarez Gonzalez, J. Ellison, Ta-Yung Ling, Alessandro Montanari, Luc Pape, Vassili Kachanov, Christopher Justus, Moritz Guthoff, Marc Weber, Konstantin Androsov, Tai Sakuma, Kevin Deroover, Anterpreet Kaur, Yutaro Iiyama, Intae Yu, Anna Elliott-Peisert, Vuko Brigljevic, Bruno Wittmer, David Taylor, Aran Garcia-Bellido, Sho Maruyama, Debarati Roy, Franco Ligabue, Kenneth Long, Avishek Chatterjee, Andrea Carlo Marini, Mehmet Vergili, Alexander Tapper, Vyacheslav Krutelyov, Suvadeep Bose, Luisa Fernanda Chaparro Sierra, Deborah Pinna, Caterina Vernieri, Alberto Andres Ocampo Rios, Alessandro Gaz, Gyorgy Bencze, Dimitri Bourilkov, and Andrew Whitbeck
Subjects: Physics, Nuclear and High Energy Physics, Particle physics, Top quark, Large Hadron Collider, Muon, Branching fraction, High Energy Physics::Phenomenology, 7. Clean energy, Standard Model, Higgs boson, High Energy Physics::Experiment, Neutrino, Nuclear Experiment, Lepton
Abstract: A search for a light charged Higgs boson, originating from the decay of a top quark and subsequently decaying into a charm quark and a strange antiquark, is presented. The data used in the analysis correspond to an integrated luminosity of 19.7 inverse femtobarns recorded in proton-proton collisions at sqrt(s) = 8 TeV by the CMS experiment at the LHC. The search is performed in the process t t-bar to W+/- b H-/+ b-bar, where the W boson decays to a lepton (electron or muon) and a neutrino. The decays lead to a final state comprising an isolated lepton, at least four jets and large missing transverse energy. No significant deviation is observed in the data with respect to the standard model predictions, and model-independent upper limits are set on the branching fraction B(t to H+ b), ranging from 1.2 to 6.5% for a charged Higgs boson with mass between 90 and 160 GeV, under the assumption that B(H+ to c s-bar) = 100%.
Published: 2015

47. Local tissue effects of various barrier membranes in a rat subcutaneous model

Author: Hyun Chang Lim, Ronald E. Jung, Christoph H. F. Hämmerle, Nadja Naenni, Franz Josef Strauss, Daniel S. Thoma, University of Zurich, and Thoma, Daniel S
Subjects: Polylactic acid-polyglycolic acid copolymer, 0206 medical engineering, Tissue integration, 610 Medicine & health, Inflammation, 02 engineering and technology, Neovascularization, 10068 Clinic of Reconstructive Dentistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, medicine, Bone regeneration, Guided tissue regeneration, 3504 Oral Surgery, Chemistry, Dental implants, 030206 dentistry, Inflammatory cell infiltration, 020601 biomedical engineering, Lactic acid, PLGA, Membrane, Periodontics, Oral Surgery, medicine.symptom, Implant Science, 3506 Periodontics, Research Article, Materials testing, Biomedical engineering
Abstract: Purpose The purpose of this study was to examine the local tissue reactions associated with 3 different poly(lactic-co-glycolic acid) (PLGA) prototype membranes and to compare them to the reactions associated with commercially available resorbable membranes in rats. Methods Seven different membranes—3 synthetic PLGA prototypes (T1, T2, and T3) and 4 commercially available membranes (a PLGA membrane, a poly[lactic acid] membrane, a native collagen membrane, and a cross-linked collagen membrane)—were randomly inserted into 6 unconnected subcutaneous pouches in the backs of 42 rats. The animals were sacrificed at 4, 13, and 26 weeks. Descriptive histologic and histomorphometric assessments were performed to evaluate membrane degradation, visibility, tissue integration, tissue ingrowth, neovascularization, encapsulation, and inflammation. Means and standard deviations were calculated. Results The histological analysis revealed complete integration and tissue ingrowth of PLGA prototype T1 at 26 weeks. In contrast, the T2 and T3 prototypes displayed slight to moderate integration and tissue ingrowth regardless of time point. The degradation patterns of the 3 synthetic prototypes were similar at 4 and 13 weeks, but differed at 26 weeks. T1 showed marked degradation at 26 weeks, whereas T2 and T3 displayed moderate degradation. Inflammatory cells were present in all 3 prototype membranes at all time points, and these membranes did not meaningfully differ from commercially available membranes with regard to the extent of inflammatory cell infiltration. Conclusions The 3 PLGA prototypes, particularly T1, induced favorable tissue integration, exhibited a similar degradation rate to native collagen membranes, and elicited a similar inflammatory response to commercially available non–cross-linked resorbable membranes. The intensity of inflammation associated with degradable dental membranes appears to relate to their degradation kinetics, irrespective of their material composition., Graphical Abstract
Published: 2020

48. Bose-Einstein correlations in pp, pPb , and PbPb collisions at sNN=0.9–7 TeV

Author: Prashant Shukla, André Rosowsky, Andrew Ivanov, P. Bloch, Stefan Wayand, Riccardo Paramatti, Andrea Giammanco, Priyanka Kumari, Betty Calpas, Michael Benjamin Andrews, Simone Paoletti, Rebecca Lane, J. C. Ruiz Vargas, Suchandra Dutta, S. Sarkar, P. E. Karchin, David Yu, F. Gonella, Giulio Mandorli, Anne-Marie Magnan, Wagner Carvalho, Terhi Jarvinen, Robert Hirosky, W. A. T. Wan Abdullah, Jamal Rorie, Jason Gilmore, Marco Paganoni, J. Seixas, Don Lincoln, Greg Landsberg, Cécile Caillol, Jory Sonneveld, Hafeez R Hoorani, Sw. Banerjee, Manjit Kaur, T. A. Verlage, A. Kumar, P. D. Dauncey, A. Castro, Andrzej Pyskir, Shawn Zaleski, Lukas Vanelderen, Stephen Sanders, Dominick Olivito, S. Roy Chowdhury, Colin Jessop, Daniel John Karmgard, Manfred Jeitler, Rishi Patel, Y. D. Oh, James Faulkner, A. Escalante Del Valle, Joosep Pata, Colin Bernet, Nadia Pastrone, Ugur Kiminsu, Suyong Choi, Etiennette Auffray, Francesco Fiori, Maurizio Biasini, Philippe Busson, A. Yagil, Sinan Sagir, Marta Felcini, Fabrizio Palla, Owen Baron, Vivekanand Jha, C. S. Moon, Mihee Jo, M. Calderon De La Barca Sanchez, L. Alunni Solestizi, Brian L Winer, Elias Pree, Maciej Misiura, Hongfang Liu, Gilvan Alves, Markus Stoye, Steve Schnetzer, Saranya Ghosh, Mehmet Özgür Sahin, Donato Creanza, Marc Dobson, Heiner Tholen, Klaas Padeken, Kai Yi, Dominik Haitz, Renato Campanini, S. Somalwar, Pedrame Bargassa, Joachim Mnich, Andreas Mussgiller, Fotios Ptochos, Riccardo Bellan, Michael Gardner, Peter Robmann, David J. Smith, Martti Raidal, Pamela Klabbers, Yen-Jie Lee, Martina Machet, C. Wissing, A. Castaneda Hernandez, Vladimir Chekhovsky, Tariq Aziz, Dave M Newbold, Burin Asavapibhop, Aram Avetisyan, Nikolay Voytishin, Umberto Dosselli, Doga Gulhan, Louis Lyons, Nikitas Loukas, Carlos Lourenco, Alessandro Giassi, Giacomo Ortona, Alexander Nehrkorn, Matthew Nguyen, Francesca Cavallari, B. Roland, Stefano Belforte, Matthias Kasemann, Paola Salvini, Maurizio Pierini, David Cussans, Marcos Fernandez, Pablo Garcia-Abia, Florian Beaudette, A. De Cosa, Hannes Sakulin, Najaf Amin, Alain Hervé, Yuri Skovpen, Suresh C Tonwar, Sylvie Braibant-Giacomelli, Jeffrey Roskes, Claudio Grandi, S. Fonseca De Souza, Giuseppe Barbagli, K. H. M. Kwok, Kira Burt, Zehui Zhang, Mauro Donegà, Sébastien Gadrat, Mayda Velasco, Mani Tripathi, Rachel Bartek, Y. Chen, Simone Pigazzini, J. Garay Garcia, Esa Tuovinen, Pedro G Mercadante, Ivan Vila, S. Carrillo Moreno, James Keaveney, Merve Nazlim Agaras, Hans-Christian Kaestli, Tilman Rohe, Jing Wang, Thomas Peiffer, G. L. Pinna Angioni, Marco Peruzzi, L. Lloret Iglesias, Usama Hussain, Owen Rosser Long, Warren Clarida, S. Tkaczyk, David Stuart, Alice Mignerey, Stefanos Leontsinis, Chayanit Asawatangtrakuldee, Yetkin Yilmaz, Marko Dragicevic, J. S. H. Lee, Vladimir Epshteyn, Josef Hrubec, E. A. De Wolf, David Sperka, Gaelle Boudoul, Salim Cerci, Markus Spanring, Alexis Kalogeropoulos, Mikhail Kirsanov, R. Cousins, D. Sunar Cerci, Daniel Arcaro, Marek Walczak, Marcella Diemoz, Dana Z. Anderson, Cesare Calabria, M. Csanad, Nicola Amapane, Lovedeep Kaur Saini, Asif Saddique, Daniel R Claes, Xin Chen, Teresa Rodrigo, Bora Akgun, T. A. Gómez Espinosa, H. Van Haevermaet, M. Bluj, Sam Harper, Luca Perrozzi, Manfred Krammer, S. h. Seo, Shuichi Kunori, Alexander Dierlamm, Cameron Bravo, Kevin Sung, Michael Northup, Teresa Lenz, Laurent Mirabito, C. Beirão Da Cruz E Silva, Steven Lowette, M. Melo De Almeida, A. Moraes, Tomas Lindén, N. Van Remortel, Malte Hoffmann, Alice Florent, Kirika Uchida, Tiziano Camporesi, Seema Sharma, Constantin Heidegger, Rostyslav Shevchenko, Laura Dodd, Andrew Levin, Carlo Civinini, Massimo Casarsa, Louise Skinnari, Vito Palladino, Nural Akchurin, Navid Rad, Yuta Takahashi, G. P. Siroli, Andrés G Delannoy, Christopher Hill, F. De Guio, Pierluigi Paolucci, I. Suárez Andrés, Shalhout Shalhout, Y. Choi, Michal Szleper, Gianni Zumerle, Andrew Beretvas, Otto Hindrichs, Aashaq Shah, Brandon Allen, Florent Lacroix, Lukas Bäni, Semiray Girgis, Yagya Raj Joshi, Matteo Sani, Andreas Nowack, Luigi Guiducci, Gregory R Snow, Matti J Kortelainen, C. Oropeza Barrera, Sioni Summers, Xin Sun, Sumit Keshri, Jared Turkewitz, A. Baden, Gino Bolla, M. Barrio Luna, Mark Foerster, Sunil Bansal, P. M. Ribeiro Cipriano, Rachel Yohay, J. K. Lim, Dustin Burns, Stefano Lacaprara, Andrew Ackert, Igor Volobouev, Anton Stepennov, Andrey Gribushin, Ashley Parker, Cheng-Chieh Peng, Roberto Chierici, Chia-Ming Kuo, D. H. Miller, Koushik Mandal, Nicholas Smith, Mateusz Zarucki, P. Martinez Ruiz del Arbol, Andrea Triossi, Christoph Schwick, Natale Demaria, Aruna Nayak, Michael Plagge, G. P. Van Onsem, T. Tabarelli de Fatis, Andrew Hart, Candan Dozen, Zaixing Mao, O. Gonzalez Lopez, Mohsen Naseri, S. Di Guida, J. Vaitkus, Simone Gennai, Zuhal Seyma Demiroglu, C. Diez Pardos, Robert Ciesielski, Michael Wayne Arenton, Bibhuprasad Mahakud, Demetrios Loukas, Giorgia Rauco, Nancy Marinelli, G. Gomez Ceballos, Nikos Varelas, Jan Kieseler, Giulia Negro, Helen F Heath, Daniel Meister, Thomas Strebler, Marc Osherson, J. H. Kim, Filippo Errico, Deepak Kumar Sahoo, Matthias Schröder, Susan Gascon, Maryam Zeinali, Patrick Jarry, Sergio P Ratti, Frank Chlebana, Urs Langenegger, Michael Buttignol, Sean Kalafut, Jian Sun, Jeremy Mans, Jean-Charles Fontaine, Anton Dimitrov, Andrea Gozzelino, Alexis Pompili, Nicola Pozzobon, Bajrang Sutar, Kuntal Mondal, Giovanni Organtini, Werner Lustermann, Andromachi Tsirou, Mohammed Mahmoud, Adrian Perieanu, A. Meyer, Paolo Spagnolo, P. Gras, Jean-Louis Faure, Philipp Millet, Artur Kalinowski, Stefan Michael Heindl, W. Ji, Brian Francis, Paolo Checchia, Alberto Messineo, John Almond, C. Mesropian, Rylan Conway, Hallie Trauger, R. Placakyte, James Strait, Andris Skuja, Sébastien Brochet, I. D. Sandoval Gonzalez, Zainol Abidin Ibrahim, Ivica Puljak, Adrian Byszuk, Louie Corpe, Hans Reithler, Ben Bylsma, Russell Richard Betts, Sheng Wang, Frank Jensen, Stephen Wimpenny, Henning Flacher, Olena Karacheban, A. Khan, Plamen Iaydjiev, Y. Kim, Gouranga Kole, Martina Malberti, J. F. de Trocóniz, Matthias Ulrich Mozer, D. E. Pellett, Nikolaos Manthos, A. Vorobyev, Konstantinos Theofilatos, A. Morelos Pineda, Shalini Thakur, Christian Laner, Martin Grunewald, Kadri Ozdemir, Sandor Czellar, Manuel Giffels, Gervasio Gomez, A. Delgado Peris, Heriberto Castilla-Valdez, James John Brooke, Stefka Stoykova, Federico Preiato, Adam Dishaw, Claudia Seitz, Kyungwook Nam, Johannes Brandstetter, Oleg Prokofyev, Wolfram Erdmann, Bobak Hashemi, Stefan Gundacker, A. Starodumov, R. Lopes De Sá, Roberto Tenchini, Nicolo Cartiglia, Benjamin Charles Radburn-Smith, Archana Sharma, Daniel Salerno, Conor Henderson, Prasenjit Mal, Christina Snyder, Konstantin Matchev, J. J. Hollar, Jean-Marie Brom, Martina Ressegotti, Dooyeon Gyun, Gunther Roland, Kittikul Kovitanggoon, Igor Bayshev, Dong Ho Moon, Adam Elwood, Brian Dorney, Pavel Bunin, Alberto Benvenuti, Daniel Pitzl, Mara Senghi Soares, Serguei Ganjour, Silvia Taroni, Giuseppe Fasanella, Sung Keun Park, Dimitri Bourilkov, Vassili Kachanov, Lindsey Gray, Kevin Nash, Valentina Dutta, Alberto Belloni, Yue Shi Lai, Bugra Bilin, Sunil Dogra, Illia Khvastunov, Meng Xiao, Kati Lassila-Perini, Petra Merkel, De Hua Zhu, Emanuela Barberis, Crisostomo Sciacca, Maxim Goncharov, Michele Selvaggi, Nicolo Magini, Tom Cornelis, Michael Dittmar, R. Kunnawalkam Elayavalli, Steven Kaplan, Marco Pieri, Guo-Ming Chen, Menglei Sun, Jacobo Konigsberg, Jorge Chaves, Si Xie, Sami Lehti, S. W. Cho, Andrew Whitbeck, Viktor Veszpremi, Abdulla Abdulsalam, Michael Seidel, J. A. Brochero Cifuentes, Ravi Janjam, Siddharth Narayanan, Shivali Malhotra, Tanmay Mudholkar, Ennio Monteil, Aldo Penzo, Aleksandar Aleksandrov, Anton Karneyeu, Leonard Apanasevich, M. Vander Donckt, Nicolas Tonon, O. Behnke, Gulsen Onengut, Viktor Matveev, H. Lee, Evgueni Vlasov, Jochen Schieck, Clemens Lange, Adish Vartak, Santiago Folgueras, George Alverson, X. Y. Gao, M. Vazquez Acosta, Valentina Mariani, Attilio Santocchia, Jeson Jacob, Jean Fay, Igor Dremin, Abideh Jafari, Rogelio Reyes-Almanza, Maria Hempel, I. Gonzalez Caballero, Shabnam Jabeen, Rohan Bhandari, Vinay Hegde, David Zou, Nathan Mirman, Andrey Korytov, P. 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Branson, Georg Steinbrück, Joschka Lingemann, Winston Ko, I. De Bruyn, Reza Goldouzian, Mohd Nizam Yusli, Barbara Clerbaux, Raúl Iraq Rabadán-Trejo, Alexander Schmidt, Nadir Daci, David Sheffield, Marcello Maggi, Renato Potenza, Cristina Tuve, R. G. Kellogg, Suneel Dutt, Guenter Eckerlin, Annik Olbrechts, Armen Tumasyan, Roberto Dell'Orso, J. W. Gary, R. Teixeira De Lima, Paula Eerola, Sergey Troshin, Manoj Sharan, Rakesh Kumar, David D'Enterria, Philip Symonds, Z. Wang, Alexis Fagot, C. E. Flores, Evangelos Paradas, Borislav Pavlov, Kevin Burkett, Ibrahim Soner Zorbakir, Csaba Hajdu, Juliana P. Duarte, Emyr Clement, Helio Nogima, Benjamin Michlin, Anita Topkar, David Vannerom, Agnieszka Zagozdzinska, Elvire Bouvier, Mario Masciovecchio, Giuseppe Iaselli, Stefano Marcellini, Huilin Qu, Georgi Sultanov, Evan Wolfe, Ari Lee, W. H. Smith, Elif Asli Yetkin, David Cutts, Kevin Stenson, C. Mora Herrera, Achim Stahl, James Letts, Troy Mulholland, M. Mohammadi Najafabadi, James Castle, Seungkyu Ha, Charles Harrington, Daniel Troendle, Panja-Riina Luukka, Daniele Fasanella, Roberto Salerno, Alberto Orso Maria Iorio, Felice Pantaleo, Chanwook Hwang, Mário Costa, Niladribihari Sahoo, D. Green, Scarlet Norberg, Olga Kodolova, Ram Krishna Dewanjee, V. P. Andreev, Daniel Winterbottom, Antony Adair, N. Cavallo, Po-Hsun Chen, Apichart Hortiangtham, Dezso Horvath, Stefano Mersi, Ryan Mueller, Ana Ovcharova, Anna Julia Zsigmond, Andrea Venturi, M. Khakzad, Tom A. Williams, D. Y. Wang, Tri Nguyen, Lalit Mohan Pant, Aaron Dominguez, Torben Dreyer, Alessia Tricomi, Nikolay Tyurin, Piet Verwilligen, Mariarosaria D'Alfonso, Mario Galanti, Zoltan Szillasi, Z. Xu, F. Rezaei Hosseinabadi, Felicitas Pauss, Roumyana Hadjiiska, Igor Smirnov, Andrey Uzunian, Christopher Palmer, Annika Vanhoefer, Alice Bean, Balazs Ujvari, Austin Baty, Aaron Levine, Paolo Giacomelli, Valerio Calvelli, Shin-Shan Yu, Jaakko Härkönen, Wenxing Fang, Geoffrey Hall, William Mcbrayer, G. N. Kim, Vytautas Dudenas, Kerstin Hoepfner, Shervin Nourbakhsh, Nabarun Dev, L. F. Chaparro Sierra, A. Bermúdez Martínez, Sanjay Padhi, B. Chazin Quero, Panagiotis Kokkas, Niels Dupont, Zhengcheng Tao, Gy L. Bencze, J. M. Hernandez, Edward Laird, Luca Mastrolorenzo, Vieri Candelise, Lana Beck, Ted Kolberg, C. Uribe Estrada, Muhammad Shoaib, Claude Charlot, Reddy Pratap Gandrajula, Pushpalatha C Bhat, Andrey Popov, L. J. Gutay, David Curry, Joonas Talvitie, Francesco Fienga, Roy Montalvo, R. Sharma, Alessandro Degano, Rishika Bhardwaj, János Karancsi, Christopher Mcginn, L. Moroni, Daniel Robert Marlow, Thea Klaeboe Aarrestad, Haiyan Wang, Yves Sirois, Mehmet Oglakci, G. Vesztergombi, Achille Petrilli, Chun-Hua Jiang, Alicia Calderon, Sachiko Toda, Sandra Oliveros, Sushil Chauhan, Kajari Mazumdar, Nickolas Mccoll, Alfredo Gurrola, Christopher Brew, Lothar At Bauerdick, Leonardo Giannini, Marcus Hohlmann, Julie Malcles, Fengwangdong Zhang, Hannes Neugebauer, Shengquan Tuo, Abhigyan Dasgupta, Zviad Tsamalaidze, Nikolai Skatchkov, Louis Antonelli, Carlos Florez, Michael Albrow, Hamed Bakhshiansohi, Stephan Linn, Marguerite Tonjes, M. Correa Martins Junior, David Mark Raymond, Olivier Bondu, E. O. Olaiya, Esteban Curras, Christophe Delaere, Jose Monroy, Alex Kamenev, Victor Kim, Willem Verbeke, Armando Lanaro, Daniel Bloch, Vivek Sharma, Adrien Caudron, Giuseppe Benedetto Cerati, Stavros Mallios, Johannes Wittmann, James D. Olsen, N. V. Krasnikov, Matthias Hamer, Lieselotte Moreels, Cyril X. George, Weinan Si, Robert M Harris, Elliot Hughes, Andrew Buccilli, Charles C. Richardson, James Bowen, Daniele Spiga, Piotr Traczyk, J. Alexander, G. M. Bilei, David Jonathan Hofman, Shubham Pandey, Thomas Klijnsma, Stanislav Lisniak, Aidan Randle-Conde, Mikhail Gavrilenko, W. S. Hou, Juska Pekkanen, M. Franco Sevilla, Giacomo Bruno, Tomas Hreus, Damir Devetak, Michele Bianco, W. E. Johns, Mariana Shopova, Eric Christian Chabert, Sean Flowers, Sandeep Bhowmik, Kristian Harder, Bo Liu, Mia Tosi, and L. Romero
Subjects: Quantum chromodynamics, Physics, Large Hadron Collider, Physics::Instrumentation and Detectors, 010308 nuclear & particles physics, Multiplicity (mathematics), Bose–Einstein correlations, 01 natural sciences, Charged particle, law.invention, Nuclear physics, Pion, law, 0103 physical sciences, Quark–gluon plasma, Nuclear Experiment, 010306 general physics, Bose–Einstein condensate
Abstract: Quantum-statistical (Bose-Einstein) two-particle correlations are measured in pp collisions at root s = 0.9, 2.76, and 7 TeV, as well as in pPb and peripheral PbPb collisions at nucleon-nucleon center-of-mass energies of 5.02 and 2.76 TeV, respectively, using the CMS detector at the Large Hadron Collider. Separate analyses are performed for same-sign unidentified charged particles as well as for same-sign pions and kaons identified via their energy loss in the silicon tracker. The characteristics of the one-, two-, and three-dimensional correlation functions are studied as functions of the pair average transverse momentum (k(T)) and the charged-particle multiplicity in the event. For all systems, the extracted correlation radii steadily increase with the event multiplicity, and decrease with increasing k(T). The radii are in the range 1-5 fm, the largest values corresponding to very high multiplicity pPb interactions and to peripheral PbPb collisions with multiplicities similar to those seen in pPb data. It is also observed that the dependencies of the radii on multiplicity and k(T) largely factorize. At the same multiplicity, the radii are relatively independent of the colliding system and center-of-mass energy.
Published: 2018

49. Search for Higgsino pair production in pp collisions at s=13 TeV in final states with large missing transverse momentum and two Higgs bosons decaying via H→bb¯

Author: John Perry Cumalat, Swagata Mukherjee, Martin Flechl, K. Hurtado Anampa, Jian Wang, Iasonas Topsis-Giotis, Patrick Jarry, Benjamin Charles Radburn-Smith, Kevin Nash, Valentina Dutta, Toni Sculac, Inkyu Park, H. Wei, Virgil E Barnes, Alessio Ghezzi, Tai Sakuma, Kevin Deroover, E. M. Da Costa, A. Rinkevicius, Giovanni Abbiendi, D. Sunar Cerci, Oliver Gutsche, Terence Libeiro, Johannes Haller, Christian Schomakers, Vadim Oreshkin, Francesca Cavallari, Anterpreet Kaur, Alexey Volkov, Yutaro Iiyama, Olivier Davignon, Dmitri Konstantinov, Francisco Yumiceva, Ritva Kinnunen, Petar Maksimovic, G. P. Van Onsem, Zaixing Mao, Andreas Pfeiffer, Kreso Kadija, O. Gonzalez Lopez, Fabio Ravera, Olena Karacheban, Maren Tabea Meinhard, Mehmet Kaya, Intae Yu, Anna Elliott-Peisert, Vuko Brigljevic, Lucia Silvestris, David Taylor, B. Jayatilaka, Aran Garcia-Bellido, Sho Maruyama, Debarati Roy, Franco Ligabue, E. Di Marco, Patrick Janot, Thorsten Chwalek, Matthew Carver, Geng-Yuan Jeng, Kenneth Long, Andrea Carlo Marini, Alexander Tapper, Vyacheslav Krutelyov, Deborah Pinna, Caterina Vernieri, Stephen Sanders, M. A. Mahmoud, Jingzhou Zhao, K. Goulianos, Nikola Godinovic, Altan Cakir, Paolo Meridiani, Tomislav Seva, Aron Soha, Simon Kurz, Pedro Silva, J. Mejia Guisao, Hyunyong Kim, René Caspart, Rajarshi Bhattacharya, Regina Demina, A. Khan, Gouranga Kole, Reyer Band, Ivan Mikulec, Francesco Micheli, Gul Gokbulut, Stefan Gundacker, A. Starodumov, Andris Skuja, Ravi Janjam, Siddharth Narayanan, Sébastien Brochet, Kirill Skovpen, J. Martin Blanco, Sourabh Dube, Anne-Laure Pequegnot, Matthew Walker, N. Zaganidis, Cecilia Elena Gerber, Gian Michele Innocenti, A. Ranieri, Livia Soffi, Christopher Seez, Ada Solano, B. De La Cruz, Samuel Higginbotham, Salvatore Costa, J. Puerta Pelayo, Indara Suarez, Anton Karneyeu, Leonard Apanasevich, M. Vander Donckt, Amitabh Lath, Simon Kudella, M. De Gruttola, Angela Mehta, Elisabetta Manca, Christoph Grab, Ajeeta Khatiwada, Jennifer A. Smith, Henning Kirschenmann, Maciej Górski, James Faulkner, A. Escalante Del Valle, Joosep Pata, Christopher Clarke, Thomas Bergauer, Michael Planer, Savvas Kyriacou, Denis Rathjens, V. A. Giakoumopoulou, Vladimir Mossolov, Sarmad Masood Shaheen, Ivica Puljak, Hans Reithler, Ben Bylsma, R. Lopes De Sá, Roberto Tenchini, Jochen Schieck, Hualin Mei, Giorgio Apollinari, Ulf Behrens, Anna Kropivnitskaya, P. de Barbaro, Stephane Perries, Carsten Heidemann, Costas Foudas, Devdatta Majumder, Colin Bernet, Ugur Kiminsu, Martti Raidal, Pamela Klabbers, Asif Saddique, Matthias Schröder, Alberto Santoro, Monika Grothe, Grigory Safronov, Charalambos Nicolaou, Niki Saoulidou, M. A. Shah, Charles Mueller, Benjamin Mesic, Emanuele Usai, J. Seixas, Suyong Choi, Caglar Zorbilmez, Meng Xiao, Jacobo Konigsberg, Alexandre Zabi, Vladimir Rekovic, S. M. A. Ghiasi Shirazi, Igor Miagkov, Marino Missiroli, C. 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Lipton, Mustafa Numan Bakirci, Reza Goldouzian, Mohd Nizam Yusli, Renato Potenza, Lorenzo Viliani, Kurt Jung, A. Baden, Gino Bolla, M. Barrio Luna, Guenter Eckerlin, Annik Olbrechts, Armen Tumasyan, R. Teixeira De Lima, Paula Eerola, Manoj Sharan, Rakesh Kumar, Mateusz Zarucki, Philip Symonds, P. Martinez Ruiz del Arbol, Z. Wang, Alexis Fagot, C. E. Flores, Evangelos Paradas, Kevin Burkett, Tri Nguyen, Lalit Mohan Pant, Aaron Dominguez, Z. Xu, Felicitas Pauss, C. Mesropian, Ayse Polatoz, Austin Baty, Valerio Calvelli, Shin-Shan Yu, Wenxing Fang, Geoffrey Hall, William Mcbrayer, G. N. Kim, Sanjay Padhi, B. Chazin Quero, Rylan Conway, Panagiotis Kokkas, J. F. de Trocóniz, Niels Dupont, Zhengcheng Tao, Gy L. Bencze, J. M. Hernandez, Edward Laird, Luca Mastrolorenzo, Vieri Candelise, Lana Beck, Ted Kolberg, C. Uribe Estrada, Muhammad Shoaib, Claude Charlot, Reddy Pratap Gandrajula, Matthias Ulrich Mozer, A. Morelos Pineda, Johannes Brandstetter, S. B. Oh, Alexander Malakhov, Günter Flügge, Qiao Xu, M. Naimuddin, Tyler Ruggles, Robert Clare, Patrizia Azzi, Thomas Hebbeker, Paul Lecoq, A. De Roeck, A. J. Campbell, A. David, Ksenia Shchelina, Albert M. Sirunyan, A. De Wit, Frans Meijers, Edward Scott, Kristian Harder, P. Bloch, Stefan Wayand, D. Cutts, Michael Benjamin Andrews, Rebecca Lane, S. Wang, Suchandra Dutta, Giulio Mandorli, Anne-Marie Magnan, Wagner Carvalho, Terhi Jarvinen, Greg Landsberg, Cécile Caillol, Manjit Kaur, Anna Colaleo, Francesco Fiori, Philippe Busson, S. Somalwar, Pedrame Bargassa, Nikolay Voytishin, K. H. M. Kwok, Kira Burt, Zehui Zhang, Merve Nazlim Agaras, Thomas Peiffer, Hasan Ogul, Loic Quertenmont, and Aram Apyan
Subjects: Physics, Particle physics, Large Hadron Collider, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Electroweak interaction, Supersymmetry, 7. Clean energy, 01 natural sciences, Supersymmetry breaking, Lightest Supersymmetric Particle, 0103 physical sciences, Higgs boson, High Energy Physics::Experiment, Higgsino, 010306 general physics, Boson
Abstract: Results are reported from a search for new physics in 13 TeV proton-proton collisions in the final state with large missing transverse momentum and two Higgs bosons decaying via H→bb¯. The search uses a data sample accumulated by the CMS experiment at the LHC in 2016, corresponding to an integrated luminosity of 35.9 fb-1. The search is motivated by models based on gauge-mediated supersymmetry breaking, which predict the electroweak production of a pair of Higgsinos, each of which can decay via a cascade process to a Higgs boson and an undetected lightest supersymmetric particle. The observed event yields in the signal regions are consistent with the standard model background expectation obtained from control regions in data. Higgsinos in the mass range 230–770 GeV are excluded at 95% confidence level in the context of a simplified model for the production and decay of approximately degenerate Higgsinos.
Published: 2018

50. The use of platelet-rich fibrin to enhance the outcomes of implant therapy: A systematic review

Author: Franz Josef Strauss, Alexandra Stähli, and Reinhard Gruber
Subjects: Bone Regeneration, Dental Implantation, Endosseous, implant therapy, 610 Medicine & health, 030206 dentistry, digestive system diseases, 03 medical and health sciences, 0302 clinical medicine, guided bone regeneration, The 5th EAO Consensus Conference, 7–10 February 2018, Pfäffikon, Schwyz, Switzerland. Guest Editor: Christoph H. F. Hämmerle, Platelet-Rich Fibrin, sinus floor elevation, Alveolar Process, Humans, Supplement Article, 030212 general & internal medicine, alveolar ridge preservation, Oral Surgery, platelet‐rich fibrin, Review Articles
Abstract: Objective To assess the impact of platelet‐rich fibrin (PRF) on implant dentistry. The primary focused question was as follows: What are the clinical, histological, and radiographic outcomes of PRF administration for bone regeneration and implant therapy? Method A systematic literature search comprised three databases: MEDLINE, EMBASE, and Cochrane followed by a hand search of relevant scientific journals. Human studies using PRF for bone regeneration and implant therapy were considered and articles published up to December 31, 2017 were included. Eligible studies were selected based on the inclusion criteria. Randomized controlled trials (RCT) and controlled clinical trials (CCT) were included. Results In total, 5,963 titles were identified with the search terms and by hand search. A total of 12 randomized controlled trials (RCT) met the inclusion criteria and were chosen for data extraction. Included studies focused on alveolar ridge preservation after tooth extraction, osseointegration process, soft tissue management, bone augmentation, bone regeneration after sinus floor elevation and surgical peri‐implantitis treatment. Overall, the risk of bias was moderate or unclear. Nine studies showed superior outcomes for PRF for any of the evaluated variables, such as ridge dimension, bone regeneration, osseointegration process, soft tissue healing. Three studies failed to show any beneficial effects of PRF. No meta‐analysis could be performed due to the heterogeneity of study designs. Conclusions There is moderate evidence supporting the clinical benefit of PRF on ridge preservation and in the early phase of osseointegration. It remains unclear whether PRF can reduce pain and improve soft tissue healing. More research support is necessary to comment on the role of PRF to improve other implant therapy outcomes.
Published: 2018
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