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2. AI-Driven Decision Support in Public Administration: An Analytical Framework

Author

de Carvalho, Victor Diogho Heuer, Todaro, Marcelo Santa Fé, dos Santos, Robério José Rogério, Nepomuceno, Thyago Celso Cavalcante, Poleto, Thiago, Figueiredo, Ciro José Jardim, Turet, Jean Gomes, de Moura, Jadielson Alves, Kacprzyk, Janusz, Series Editor, Gomide, Fernando, Advisory Editor, Kaynak, Okyay, Advisory Editor, Liu, Derong, Advisory Editor, Pedrycz, Witold, Advisory Editor, Polycarpou, Marios M., Advisory Editor, Rudas, Imre J., Advisory Editor, Wang, Jun, Advisory Editor, Rocha, Álvaro, editor, Ferrás, Carlos, editor, Hochstetter Diez, Jorge, editor, and Diéguez Rebolledo, Mauricio, editor

Published
2024
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8. Integration of the waterfall model with ISO/IEC/IEEE 29148:2018 for the development of military defense system

Author

Edgard Candido de Oliveira Neto, Rafael Ris-Ala Jose Jardim, Marcos Dos Santos, Frederico Carlos Muthz Medeiros de Barros, and Eliseu Dias da Silva

Subjects
0209 industrial biotechnology, Engineering, Geographic information system, General Computer Science, Requirements engineering, business.industry, Software development, 020207 software engineering, 02 engineering and technology, Domain (software engineering), Software development process, System requirements, Engineering management, 020901 industrial engineering & automation, Software, Waterfall model, 0202 electrical engineering, electronic engineering, information engineering, Electrical and Electronic Engineering, business
Abstract

Software development for military organizations follows standards and a set of guidelines established in the requirements engineering domain. However, these procedures are not always documented and it is difficult to reach understanding among stakeholders with varied backgrounds and interests. This article aims to obtain lessons learned through a case study of the development of a defense system for the Armed Forces of Brazil. From the validation of requirements specialist, a software development lifecycle was obtained that integrates the waterfall model and ISO/IEC/IEEE 29148 recommendations. The use of the model obtained facilitated the understanding of the processes that involved military teams, detailed specification of system requirements and success in the geoinformation based prototype.

Published
2020

9. COPD: Providing the right treatment for the right patient at the right time

Author

Alvar Agusti, Nicolino Ambrosino, Felicity Blackstock, Jean Bourbeau, Richard Casaburi, Bartolome Celli, Gerard J. Criner, Rebecca Crouch, Roberto W. Dal Negro, Michael Dreher, Chris Garvey, Daniel A. Gerardi, Roger Goldstein, Nicola A. Hanania, Anne E. Holland, Antarpreet Kaur, Suzanne Lareau, Peter K. Lindenauer, David Mannino, Barry Make, François Maltais, Jeffrey D. Marciniuk, Paula Meek, Mike Morgan, Jean-Louis Pepin, Jane Z. Reardon, Carolyn L. Rochester, Sally Singh, Martijn A. Spruit, Michael C. Steiner, Thierry Troosters, Michele Vitacca, Enico Clini, Jose Jardim, Linda Nici, Jonathan Raskin, Richard ZuWallack, University of Barcelona, Istituti Clinici Scientifici Maugeri [Pavia] (IRCCS Pavia - ICS Maugeri), La Trobe University [Melbourne], McGill University = Université McGill [Montréal, Canada], UCLA School of Medicine [Torrance, CA, USA], Harvard Medical School [Boston] (HMS), Campbell University [Buies Creek, NC, USA] (CU), CESFAR - Centro Nazionale Studi di Farmacoeconmia, Universitätsklinikum RWTH Aachen - University Hospital Aachen [Aachen, Germany] (UKA), Rheinisch-Westfälische Technische Hochschule Aachen University (RWTH), UCSF Sleep Disorders [San Francisco, CA, USA], Trinity Health of New England [Hartford, CT, USA] (THNE), West Park Health Care Centre [Toronto, ON, Canada] (WPH2C), Baylor College of Medicine (BCM), Baylor University, Monash University [Melbourne], University of Colorado Anschutz [Aurora], University of Massachusetts System (UMASS), University of Kentucky (UK), National Jewish Health (NJH), Institut Universitaire de Cardiologie et de Pneumologie de Québec (IUCPQ), Université Laval [Québec] (ULaval), University of Saskatchewan [Saskatoon] (U of S), University of Utah, University of Leicester, Hypoxie et PhysioPathologie (HP2), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Yale University [New Haven], CIRO [Horn, The Netherlands], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), Università degli Studi di Modena e Reggio Emilia = University of Modena and Reggio Emilia (UNIMORE), Federal University of Sao Paulo (Unifesp), Brown University, Mount Sinai School of Medicine, Department of Psychiatry-Icahn School of Medicine at Mount Sinai [New York] (MSSM), Université Saint-Francis-Xavier (CANADA), and SALAS, Danielle

Subjects
[SDV] Life Sciences [q-bio], Pulmonary and Respiratory Medicine, COPD, Pulmonary Rehabilitation, Non-Pharmacologic Treatment, Comprehensive Care of the COPD Patient, [SDV]Life Sciences [q-bio]
Abstract

International audience; Chronic Obstructive Pulmonary Disease (COPD) is a common disease associated with significant morbidity and mortality that is both preventable and treatable. However, a major challenge in recognizing, preventing, and treating COPD is understanding its complexity. While COPD has historically been characterized as a disease defined by airflow limitation, we now understand it as a multi-component disease with many clinical phenotypes, systemic manifestations, and associated co-morbidities. Evidence is rapidly emerging in our understanding of the many factors that contribute to the pathogenesis of COPD and the identification of "early" or "pre-COPD" which should provide exciting opportunities for early treatment and disease modification. In addition to breakthroughs in our understanding of the origins of COPD, we are optimizing treatment strategies and delivery of care that are showing impressive benefits in patient-centered outcomes and healthcare utilization. This special issue of Respiratory Medicine, "COPD: Providing the Right Treatment for the Right Patient at the Right Time" is a summary of the proceedings of a conference held in Stresa, Italy in April 2022 that brought together international experts to discuss emerging evidence in COPD and Pulmonary Rehabilitation in honor of a distinguished friend and colleague, Claudio Ferdinando Donor (1948-2021). Claudio was a true pioneer in the field of pulmonary rehabilitation and the comprehensive care of individuals with COPD. He held numerous leadership roles in in the field, provide editorial stewardship of several respiratory journals, authored numerous papers, statement and guidelines in COPD and Pulmonary Rehabilitation, and provided mentorship to many in our field. Claudio's most impressive talent was his ability to organize spectacular conferences and symposia that highlighted cutting edge science and clinical medicine. It is in this spirit that this conference was conceived and planned. These proceedings are divided into 4 sections which highlight crucial areas in the field of COPD: (1) New concepts in COPD pathogenesis; (2) Enhancing outcomes in COPD; (3) Non-pharmacologic management of COPD; and (4) Optimizing delivery of care for COPD. These presentations summarize the newest evidence in the field and capture lively discussion on the exciting future of treating this prevalent and impactful disease. We thank each of the authors for their participation and applaud their efforts toward pushing the envelope in our understanding of COPD and optimizing care for these patients. We believe that this edition is a most fitting tribute to a dear colleague and friend and will prove useful to students, clinicians, and researchers as they continually strive to provide the right treatment for the right patient at the right time. It has been our pleasure and a distinct honor to serve as editors and oversee such wonderful scholarly work.

Published
2023

11. Sussurros do Coração

Author

Maria José Jardim Godoi and Maria José Jardim Godoi

Abstract

Eis que o coração sussurra para si mesmo:'Só o seu amor me basta? Sou mesmo prisioneiro do amor? Mereço ser castigado por cometer crimes de amor?'. É entre perguntas e devaneios que a autora apresenta esses poemas recheados de saudades, mas que, ao mesmo tempo, trazem a sensação de que a distância não impede o coração de amar intensamente... Em meio a tantas dúvidas, desa fia o leitor a buscar as respostas no fundo do coração, onde talvez o maior desafi o seja descobrir se a felicidade tem prazo de validade.

Published
2023

12. Benralizumab for the Prevention of COPD Exacerbations

Author

Criner, G. J., Celli, B. R., Brightling, C. E., Agusti, A., Papi, A., Singh, D., Sin, D. D., Vogelmeier, C. F., Sciurba, F. C., Bafadhel, M., Backer, V., Kato, M., Ramirez-Venegas, A., Wei, Y. -F., Bjermer, L., Shih, V. H., Jison, M., O'Quinn, S., Makulova, N., Newbold, P., Goldman, M., Martin, U. J., GALATHEA Study Investigators, TERRANOVA Study Investigators, Otto, Burghuber, Bernhard, Forstner, Gerhard, Köberl, Bernd, Lamprecht, Judith, Löffler-Ragg, Horst, Olschewski, Michael, Studnicka, Francois, Beaucage, Guy, Chouinard, Anthony, Dechant, Anthony, Dowell, Jacques, Hebert, Sohail, Khattak, Kieran, Killian, William, Killorn, Andy, Lam, Francois, Maltais, Darcy, Marciniuk, Lyle, Melenka, Bonavuth, Pek, Jeremy, Road, Donald, Sin, Alain, Vaugeois, Brandie, Walker, Tomas, Dvorak, Stanislav, Holub, Otakar, Hokynar, Vitezslav, Kolek, Daniela, Kopecka, Jan, Krepelka, Jaroslav, Mares, Josef, Veverka, Vladimir, Zindr, Sabine, Ballenberger, Rolf, Dichmann, Christian, Geßner, Margret, Jandl, Claus, Keller, Joachim, Kirschner, Marc, Kornmann, Petra, Mikloweit, Ingomar, Naudts, Axel, Overlack, Isabelle, Schenkenberger, Volker, Schlegel, Lutz Von Versen, Claus Franz Vogelmeier, Stefan, Zielen, István, Albert, Beatrix, Bálint, Mária Csilla Hangonyi, Teréz, Kecskés, Anikó, Kurucz, Balázs, Medgyasszay, Lajos, Molnár, János, Mucsi, Márta, Papp, Magdolna, Póczi, Éva, Radeczky, Zsolt Pápai Székely, Csilla, Szabó, Gyöngyi, Szabó, Melinda, Szabó, Alfredo Antonio Chetta, Giuseppe Di Maria, Giulio, Donazzan, Federica, Meloni, Elisabetta, Pace, Pierluigi, Paggiaro, Alberto, Papi, Ricciardolo, Fabio Luigi Massimo, Antonio, Spanevello, Fumiaki, Aoki, Ryosuke, Eda, Takeo, Endo, Yasushi, Fukushima, Kenichi, Gemba, Naoki, Hagimoto, Hiromasa, Harada, Yasuko, Harada, Norihiko, Hata, Osamu, Hataji, Nobuo, Hatakeyama, Takahiko, Horiguchi, Gen, Ideura, Motoyasu, Iikura, Azusa, Ikegami, Shirou, Imokawa, Yoshikazu, Inoue, Takeshi, Isobe, Ryoji, Ito, Susumu, Iwata, Tadashi, Kamei, Motokazu, Kato, Hideki, Katsura, Yuji, Kawarada, Norio, Kihara, Masaharu, Kinoshita, Takashi, Kinoshita, Tomoo, Kishaba, Hideo, Kita, Arihiro, Kiyosue, Shigeru, Komatsu, Kazuki, Konishi, Sekiya, Koyama, Makoto, Kudo, Kazuhiko, Machida, Hironi, Makita, Hiroto, Matsuse, Naoki, Miyazawa, Hiroyuki, Nakamura, Yuji, Nakatani, Kazuyuki, Nishimura, Takashi, Nishimura, Junichi, Ogawa, Hiroyuki, Ohbayashi, Tetsuro, Ohdaira, Tsukasa, Ohnishi, Kazuhiko, Oki, Masahiko, Saito, Kenji, Sakamoto, Osamu, Sakamoto, Hisakuni, Sekino, Noriharu, Shijubo, Masaharu, Shinkai, Hideo, Soto, Yoshitaka, Sugawara, Noriaki, Suko, Hisaho, Takahashi, Masamitsu, Takahashi, Tsuneyuki, Takahashi, Hiroshi, Tanaka, Hiroyuki, Taniguchi, Tadayuki, Terada, Takao, Tochigi, Kazuyo, Tohyama, Hirokazu, Tokuyasu, Keisuke, Tomii, Tomomasa, Tsuboi, Mitsuyoshi, Utsugi, Katsumaru, Yamamoto, Michiko, Yamamoto, Shuichi, Yano, Makoto, Yoshida, Frank, Custers, Richard, Dekhuijzen, Remco, Djamin, Jan Willem Van Dan Berg, Lowie, Vanfleteren, Pascal, Wielders, Bogusława, Cimoszko, Anna, Doboszyńska, Andrzej, Dyczek, Andrzej, Fal, Krystyna, Folcik, Łukasz, Goliński, Marek, Jutel, Andrzej, Kolczyński, Piotr, Kuna, Ewa, Łączyńska, Wojciech, Machowiak, Maciej, Marczak, Joanna, Markiewicz, Janusz, Milanowski, Grzegorz, Mincewicz, Maria, Nittner-Marszalska, Wojciech, Papiewski, Małgorzata, Pawlukiewicz, Witold, Pomiećko, Barbara, Rewerska, Cezary, Rybacki, Wojciech, Skucha, Ewa, Trębas-Pietraś, Ewa, Uhryn, Małgorzata, Żurowska-Gębala, Laurentia, Andrei, Traian, Mihaescu, Stefan, Mihaicuta, Eniko Vera Pall, Ioan, Petrui, Angelica, Savu, Claudia, Toma, Ana, Trailescu, Vladimir, Abrosimov, Nataliya, Astafyeva, Evgenyi, Bazdyrev, Nadezhda, Berdnikova, Laura, Bolieva, Ekaterina, Bukreeva, Valery, Chistyakov, Anna, Galustyan, Halida, Gantseva, Svetlana, Goncharova, Sergey, Grigoriev, Galina, Ignatova, Inna, Ilyashevich, Nadezhda, Izmozherova, Magomed, Kamalov, Yaroslava, Khovaeva, Natalia, Kuzubova, Lyudmila, Kvitkova, Liudmila, Lenskaya, Igor, Leshchenko, Olga, Magnitskaya, Boris, Molotilov, Artem, Molotkov, Svetlana, Myasoedova, Sergey, Nedogoda, Vladimir, Nosov, Marina, Osipenko, Andrey, Peskov, Veronika, Popova, Oksana, Ratushnay, Irina, Ryzhova, Olga, Shangina, Natalia, Shaporova, Evgeny, Shmelev, Lybov, Shpagina, Alexander, Shutkin, Yuri, Shvarts, Mikhail, Smirnov, Irina, Stitsenko, Maksim, Vasilev, Arkadiy, Vertkin, Elena, Vishneva, Alexander, Vizel, Anna, Zateyschikova, Mohamed, Abdool-Gaffar, Ismail, Abdullah, Axel, Bruning, Nyda, Fourie, Michael, Greenblatt, Mohammed, Tayob, Venter, K, An Soo Jang, Kwan Ho Lee, Sang Haak Lee, Sook Young Lee, Suk Joong Yong, Kwang Ha Yoo, Soo Taek Uh, Ramón Agüero Balbín, David Ramos Barbón, Álvar Agustí García-Navarro, José Luis Velasco Garrido, Sergi Pascual Guardia, Eduard Monso Molas, Luis De Teresa Parreño, Borja García-Cosio Piqueras, German Peces-Barba Romero, Myriam Calle Rubio, Fernando Sánchez-Toril López, Alicia Marín Tapia, Heidi Martin Braschler, Martin, Brutsche, Michael, Grob, Jörg, Leuppi, Daiana, Stolz, Alexander, Turk, Nawar, Bakerley, Mona, Bafadhel, Christopher, Brightling, Rekha, Chaudhuri, Gourab, Choudhury, Graham, Devereux, Imran, Hussain, Kai, Lee, William, Macnee, Ravindran, Mahadeva, Matthew, Masoli, Monica, Nordstrom, Manish, Patel, Allan, Reid, Dinesh, Saralaya, Tariq, Sethi, Sukh Dave Singh, Anthony, G de Soyza, Tom, Wilkinson, Alice, Turner, Helen, Ward, Chandar, Abboy, Ivan, Ackerman, Idalia, Acosta, Arun, Adlakha, Bassil, Aish, Mohamed, Ali, Charles, Andrews, Robby, Ayoub, Anil, Badhwar, Dennis, Bassetti, Sherif El Bayadi, Richard, Beasley, Shashi, Bellam, Jonathan, Bernstein, Maria, Blahey, Scott, Bloom, Eugene, Bleecker, Wesley, Bray, Johnathan, Brewer, Robert, Buynak, William, Calhoun, Edward, Campbell, Anthony, Captain, Birjis, Chinoy, Kenneth, Chinsky, Geoffrey, Chupp, Arsenio, Columbie, Clinton, Corder, Gerard, Criner, Humberto, Cruz, Edward, Cullen, Kevin, Deboer, Michael, Denenberg, Mark, Dransfield, Leonard, Dunn, Miles, Elmore, David, Erb, Faisal, Fakih, Gary, Ferguson, Charles, Fogarty, Mark, Freed, Stephen, Fritz, David, Fuentes, Shariar, Cohen-Gadol, Robert, Garver, John, Given, Luis Ramos Gonez, Raul Ebran Gonzalez, Robert, Gordon, Gregory, Gottschlich, Donald, Graham, David, Grant, Gary, Greenwald, James, Greenwald, Kenneth, Haft, Gregory, Hammond, Nadia, Hansel, Jeffrey, Harris, Humberto, Hernandez, Marvin, Heuer, Albrecht, Heyder, David, Hill, Willis, Holloway, Octavian, Ioachimescu, Richard, Jackson, Ajay, Jain, Nan, Jiang, Thomas, Kaelin, Adolfo, Kaplan, Mitchell, Kaye, Akram, Khan, Yekaterina, Khronusova, Ryan, Klein, Joel, Kline, Firas, Koura, Ritsu, Kuno, Ware, Kuschner, Jean Claude Labissiere, David Laman Jr, John, Lee, Mitchell, Lee, Lawrence, Levinson, Njira, Lugogo, Mador, M, Nathaniel, Marchetti, Rafael, Martinez, Richard, Martinez, Peter, Mattar, David, Maybee, Dennis, Mcgraw, Michael, Mcguire, Curtis, Mello, Aaron, Milstone, John, Mitchell, Wendy, Moore, Timothy, Moriarty, Cheta, Nand, Brooke, Nevins, Ikeadi, Ndukwu, Rachel, Nisbet, David, Nyanjom, Maria, Nualart, Thomas, O'Brien, Mikhail, Palatnik, Gnyandev, Patel, Amit, Patel, Guido, Perez, Christopher, Perry, Michael, Pfeffer, Krishna, Pudi, Marina, Raikhel, Murali, Ramaswamy, Joe, Ramsdell, Donato, Ricci, Gary, Richmond, Eugene, Ryan, Fadi, Saba, Boris, Sagalovich, C Andrew Schroeder, Timothy, Scialla, Frank, Sciurba, Amit, Shah, Nirav, Shah, Zeeshan, Shaikh, Akhtar, Siddiqui, Barry, Sigal, Thomas, Siler, Howard, Silverboard, William, Sims, Clyde, Southwell, Selwyn, Spangenthal, Peruvemba, Sriram, James, Stocks, Tony, Su, John, Suen, Robert, Sussman, Horia, Tatu, Antonio, Terrelonge, Alan, Thomas, Mario, Torres, Rodolfo, Trejo, Miguel, Trevino, Banks, Turner, Manuel, Villareal, Janine, Vintch, Neal, Warshoff, Jan, Westerman, Philip, Wexler, Thomas, Yunger, Amir, Zeki, Mariano Fernandez Acquier, Norma, Aramayo, German, Arce, Juan, Belloni, Víctor, Cambursano, Carlos De La Vega, Fernando Rodriguez Chariarse, Pedro, Elias, Marcelo, Fernández, Ana, Lopez, Andrea, Medina, María, Otaola, Maria Salazan Saez, Maria De Salvo, Fernando, Scherbovsky, Ana, Stok, Jorge, Taborda, Alberto, Tolcachier, Fernando, Verra, Carlos, Victorio, Rita Gisela Delgado Vizcarra, Philip, Bardin, Peter, Bremner, Martin, Phillips, John, Upham, Peter, Wark, Antoine, Bolly, Alain, Delobbe, Peter, Driesen, Eduard, Janssens, Wim, Janssens, Olivier, Michel, Bernard, Vandooren, Martti, Antila, Jussara, Fiterman, Carlos, Fritscher, Jorge, Hetzel, Jose, Jardim, Waldo De Mattos, Rafael, Martins, Maria Eunice De Oliveira, Andreia, Pez, Maria, Sales, Rafael, Stelmach, Priscila, Wolff, Svetla, Andreeva, Reneta, Antonova, Ana, Dancheva, Yuliya, Ivanova, Slavcho, Ivanov, Hristo, Metev, Iveta, Naydenova, Tatyana, Petkova, Galina, Petrova, Kostadinka, Sotirova, Mariyana, Stoyanova, Rumen, Tiholov, Iliyana, Valkanova, Oleg, Yakov, Rosa, Feijoo, Juana, Pavie, Patricia, Schönffeldt, Absalon, Silva, Victor, Martinez, David, Espinosa, Alejandro, Londono, Dora, Molina, Gonzalo, Prada, Andrés, Rico, Gregorio Sanchez Vallejo, Alvaro, Urbina, Ana, Vanegas, Maria, Villegas, Josip, Aralica, Gordana, Stjepanovic, Vibeke, Backer, Uffe, Bødtger, Christian, Meyer, Læge Sven Nielsen, Anders Loekke Ottesen, Ingrid, Titlestad, Nathalie, Bautin, Arnaud, Bourdin, Pascal, Chanez, Francis, Couturaud, Antoine, Cuvelier, Gilles, Devouassoux, Pierre-Olivier, Girodet, Jean-François, Muir, Jean-Louis, Pépin, Alain, Proust, Azzedine, Yaici, Yochai, Adir, Gershon, Fink, Zvi, Fridlender, Gabriel, Izbicki, Mordechai, Kramer, Yehuda, Schwartz, Juan Moreno Hoyos Abril, Ricardo Campos Cerda, Efraín Montaño Gonzalez, Ricardo Ramirez Terrones, Rodolfo Posadas Valay, Alejandra, Ramirez-Venegas, Paul, Dawkins, Syed, Hussain, Benedict, Brockway, John, Richmond, Colin, Helm, Catherina, Chang, Jørn, Ahlqvist, Terje, Tollåli, Tadeusz, Tomala, Socorro, Castro, William, Chavez, Octavio, Cubas, Rolando, Estrella, Efrain, Felix, Ronal, Gamarra, Alfredo, Guerreros, Alberto, Matsuno, Danilo, Salazar, Miguel, Tsukayama, Albert Albay Jr, Teresita, Aquino, Tito, Atienza, Joven Roque Gonong, Ronnie, Samoro, Joel, Santiaguel, Beata, Asankowicz-Bargiel, Ewa, Pisarczyk-Bogacka, Renata, Bijata-Bronisz, Marta, Chełmińska, Małgorzata, Dobryniewska, Anna, Olech-Cudzik, Tomasz, Fijołek, Krzysztof, Filipek, Agata, Kot, Bożena, Kucińska, Krzysztof, Lis, Elżbieta, Rybicka-Liszewska, Marzenna, Tarnowska-Matusiak, Robert, Mróz, Piotr, Napora, Wojciech, Naumnik, Artur, Niemiec, Władysław, Pierzchała, Grzegorz, Przybylski, Katarzyna, Styka, Danuta, Wrońska, Branislava, Milenkovic, Dobrivoje, Novkovic, Matijaz, Flezar, Niksa, Segota, Snezana Ulcar Kostic, Albert, Klobucar, Leif, Bjermer, Dan, Curiac, Christer, Janson, Pekka, Koskinen, Lundback, Bo, Åke, Olsson, Shih-Lung, Cheng, Ming-Lin, Ho, Jeng-Yuan, Hsu, Wu-Huei, Hsu, Ping-Hung, Kuo, Chin-Chou, Wang, Yu-Feng, Wei, Kuang-Yao, Yang, Watchara, Boonsawat, Somchai, Chantarothorn, Warangkana, Keeratichananont, Kittipong, Maneechotesuwan, Kanok, Pipatvech, Piamlarp, Sangsayunh, Sibel, Arinc, Sermin, Borekci, Arzu Kaner Erturk, Filiz, Kosar, Hakan, Gunen, Ismail, Hanta, Pinar Akin Kabalak, Tunc Alp Demir, Sibel, Nayci, Serir Aktogu Ozkan, Abdullah, Sayiner, Esra, Uzaslan, Viktor, Blazhko, Volodymyr, Gavrysyuk, Olena, Golub, Liudmyla, Iashyna, Tetiana, Ilashchuk, Volodymyr, Koshlia, Olena, Krakhmalova, Vitali, Kryvenko, Lesia, Kuryk, Olena, Levchenko, Yuriy, Mostovoy, Mykola, Ostrovskyy, Tetyana, Pertseva, Olena, Piura, Nadiya, Rudnytska, Ganna, Stupnytska, Nataliia, Velychko, Oleh, Yakovenko, Lilia Rodriguez Ables, Roger, Abrahams, Jose, Alvarez, Fernando, Arencibia, Chander, Arora, Samir, Arora, Francis, Averill, Kwabena, Ayesu, Stephen, Basheda, Steven, Bauer, Jose, Bautista, Matthew, Beacom, Hernando, Bernal, Subodh, Bhuchar, J'Cinda, Bitters, John, Burk, Elizabeth, Burkett, James, Cain, Robert, Call, Christopher, Chappel, Bartolome, Celli, Tom, Christensen, Jeremy, Cole, Jerome, Daniel, Nguyen, Dang, Enrique, Davis, Samuel, Deleon, Robert, Deluca, Ernesto, Diaz, Anthony, Dimarco, Calvin, Dixon, Ankur, Doshi, Hugh, Durrence, Alain, Eid, John, Elsen, Herbon, Fleming, May, Flores, Scott, Franczek, Gregory, Funk, Stuart, Garay, Bernard, Garcia, Joseph, Graif, Carl, Griffin, Yamirka Duardo Guerra, David, Headley, Mitzie, Hewitt, Susan, Hole, Robert, Holladay, Ira, Horowitz, Yu-Luen, Hsu, Jonathan, Ilowite, Stephen, Jones, Ravindra, Kashyap, Edward, Kerwin, Ahtaram, Khan, Nicole, Kimzey, James, Krainson, Flory, Kreutter, Kannappan, Krishnaswamy, Shahrukh, Kureishy, Albert, Lai, Alex, Lechin, Daria, Lee, Marcus, Lee, Williams, Leeds, Joseph, Lillo, Edward, Lisberg, Lawrence, Madoff, Narendra, Maheskwari, Mujibur, Majumder, Sashi, Makam, Douglas, Mapel, Matthew, Mardiney, Jennifer, Martin, Isaac, Melamed, Elvin, Mendez, Stuart, Millstone, Joseph, Montes, Lee, Morrow, Frank, Murphy, Dany, Obeid, France, Occy, Godson, Oguchi, Juan, Ortiz, Francisco, Padron, Ward, Paine, James, Pearle, Enrique, Pelayo, Vandely, Perez, David, Pham, Carlos, Piniella, Kevin, Pritchett, Padmashri, Rastogi, Stephen, Ryan, Syed, Rehman, Jackson, Rhudy, Eustace, Riley, James, Riser, Clifford, Risk, Emory, Robinette, Christopher, Roney, Gary, Ruoff, David, Russian, Mercedes, Samson, Jay, Sandberg, Jose, Santiago, William, Sargeant, Alan, Schecter, Jeffrey, Scott, Ilia, Segal, Sudhir, Sehgal, Frederic, Seifer, Sudhir, Sekhsaria, Richard, Sellman, Paul, Shapero, Jeffrey, Shea, Lawrence, Sher, John, Sibille, Jawed, Siddiqui, Toniya, Singh, Deren, Sinkowitz, Denise, Smyth, Daniel, Soteres, Daniel, Sousa, Ralph, Steele, Thomas, Stern, Jose, Suarez, Sever, Surdulescu, Ricardo, Tan, Tonny, Tanus, Raymond, Tidman, Aurelio, Torres-Consuegra, Barry, Troyan, John, Updegrove, Sanjay, Vadgama, Armando, Pineda-Velez, Eduardo, Viera, Andrew, Wachtel, Ralph, Wade, Jimin, Wang, Dave, Webster, Paul, Weinberg, Terry, Wells, Jeffrey, White, Bram, Wieskopf, Hugh, Windom, Patrick, Wright, David, Wyatt, Bassam, Yousef, Zahid, Zafar, Chau, Ngo, Huong, Le, Lan, Nguyen, Thanh, Nguyen, Nhung, Nguyen, SALAS, Danielle, Temple University [Philadelphia], Pennsylvania Commonwealth System of Higher Education (PCSHE), Harvard Medical School [Boston] (HMS), University of Leicester, University of Barcelona, Università degli Studi di Ferrara = University of Ferrara (UniFE), University of Manchester [Manchester], St. Paul’s Hospital - University of British Columbia [Vancouver, BC, Canada] (SPH-UBC), Philipps Universität Marburg = Philipps University of Marburg, University of Pittsburgh School of Medicine, University of Oxford, Bispebjerg University Hospital [Copenhagen, Denmark] (BUH), Kishiwada City Hospital [Osaka, Japan] (KCH), Instituto Nacional de Enfermedades Respiratorias [México, Mexico], I-Shou University [Kaohsiung, Taiwan] (ISU), Lund University [Lund], AstraZeneca [Gaithersburg, MD, USA] (AZ), Hypoxie et PhysioPathologie (HP2), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), and Otto Burghuber, Bernhard Forstner, Gerhard Köberl, Bernd Lamprecht, Judith Löffler-Ragg, Horst Olschewski, Michael Studnicka, Francois Beaucage, Guy Chouinard, Anthony Dechant, Anthony Dowell, Jacques Hebert, Sohail Khattak, Kieran Killian, William Killorn, Andy Lam, Francois Maltais, Darcy Marciniuk, Lyle Melenka, Bonavuth Pek, Jeremy Road, Donald Sin, Alain Vaugeois, Brandie Walker, Tomas Dvorak, Stanislav Holub, Otakar Hokynar, Vitezslav Kolek, Daniela Kopecka, Jan Krepelka, Jaroslav Mares, Josef Veverka, Vladimir Zindr, Sabine Ballenberger, Rolf Dichmann, Christian Geßner, Margret Jandl, Claus Keller, Joachim Kirschner, Marc Kornmann, Petra Mikloweit, Ingomar Naudts, Axel Overlack, Isabelle Schenkenberger, Volker Schlegel, Lutz Von Versen, Claus Franz Vogelmeier, Stefan Zielen, István Albert, Beatrix Bálint, Mária Csilla Hangonyi, Teréz Kecskés, Anikó Kurucz, Balázs Medgyasszay, Lajos Molnár, János Mucsi, Márta Papp, Magdolna Póczi, Éva Radeczky, Zsolt Pápai Székely, Csilla Szabó, Gyöngyi Szabó, Melinda Szabó, Alfredo Antonio Chetta, Giuseppe Di Maria, Giulio Donazzan, Federica Meloni, Elisabetta Pace, Pierluigi Paggiaro, Alberto Papi, Fabio Luigi, Massimo Ricciardolo, Antonio Spanevello, Fumiaki Aoki, Ryosuke Eda, Takeo Endo, Yasushi Fukushima, Kenichi Gemba, Naoki Hagimoto, Hiromasa Harada, Yasuko Harada, Norihiko Hata, Osamu Hataji, Nobuo Hatakeyama, Takahiko Horiguchi, Gen Ideura, Motoyasu Iikura, Azusa Ikegami, Shirou Imokawa, Yoshikazu Inoue, Takeshi Isobe, Ryoji Ito, Susumu Iwata, Tadashi Kamei, Motokazu Kato, Hideki Katsura, Yuji Kawarada, Norio Kihara, Masaharu Kinoshita, Takashi Kinoshita, Tomoo Kishaba, Hideo Kita, Arihiro Kiyosue, Shigeru Komatsu, Kazuki Konishi, Sekiya Koyama, Makoto Kudo, Kazuhiko Machida, Hironi Makita, Hiroto Matsuse, Naoki Miyazawa, Hiroyuki Nakamura, Yuji Nakatani, Kazuyuki Nishimura, Takashi Nishimura, Junichi Ogawa, Hiroyuki Ohbayashi, Tetsuro Ohdaira, Tsukasa Ohnishi, Kazuhiko Oki, Masahiko Saito, Kenji Sakamoto, Osamu Sakamoto, Hisakuni Sekino, Noriharu Shijubo, Masaharu Shinkai, Hideo Soto, Yoshitaka Sugawara, Noriaki Suko, Hisaho Takahashi, Masamitsu Takahashi, Tsuneyuki Takahashi, Hiroshi Tanaka, Hiroyuki Taniguchi, Tadayuki Terada, Takao Tochigi, Kazuyo Tohyama, Hirokazu Tokuyasu, Keisuke Tomii, Tomomasa Tsuboi, Mitsuyoshi Utsugi, Katsumaru Yamamoto, Michiko Yamamoto, Shuichi Yano, Makoto Yoshida, Frank Custers, Richard Dekhuijzen, Remco Djamin, Jan Willem Van Dan Berg, Lowie Vanfleteren, Pascal Wielders, Bogusława Cimoszko, Anna Doboszyńska, Andrzej Dyczek, Andrzej Fal, Krystyna Folcik, Łukasz Goliński, Marek Jutel, Andrzej Kolczyński, Piotr Kuna, Ewa Łączyńska, Wojciech Machowiak, Maciej Marczak, Joanna Markiewicz, Janusz Milanowski, Grzegorz Mincewicz, Maria Nittner-Marszalska, Wojciech Papiewski, Małgorzata Pawlukiewicz, Witold Pomiećko, Barbara Rewerska, Cezary Rybacki, Wojciech Skucha, Ewa Trębas-Pietraś, Ewa Uhryn, Małgorzata Żurowska-Gębala, Laurentia Andrei, Traian Mihaescu, Stefan Mihaicuta, Eniko Vera Pall, Ioan Petrui, Angelica Savu, Claudia Toma, Ana Trailescu, Vladimir Abrosimov, Nataliya Astafyeva, Evgenyi Bazdyrev, Nadezhda Berdnikova, Laura Bolieva, Ekaterina Bukreeva, Valery Chistyakov, Anna Galustyan, Halida Gantseva, Svetlana Goncharova, Sergey Grigoriev, Galina Ignatova, Inna Ilyashevich, Nadezhda Izmozherova, Magomed Kamalov, Yaroslava Khovaeva, Natalia Kuzubova, Lyudmila Kvitkova, Liudmila Lenskaya, Igor Leshchenko, Olga Magnitskaya, Boris Molotilov, Artem Molotkov, Svetlana Myasoedova, Sergey Nedogoda, Vladimir Nosov, Marina Osipenko, Andrey Peskov, Veronika Popova, Oksana Ratushnay, Irina Ryzhova, Olga Shangina, Natalia Shaporova, Evgeny Shmelev, Lybov Shpagina, Alexander Shutkin, Yuri Shvarts, Mikhail Smirnov, Irina Stitsenko, Maksim Vasilev, Arkadiy Vertkin, Elena Vishneva, Alexander Vizel, Anna Zateyschikova, Mohamed Abdool-Gaffar, Ismail Abdullah, Axel Bruning, Nyda Fourie, Michael Greenblatt, Mohammed Tayob, K Venter, An Soo Jang, Kwan Ho Lee, Sang Haak Lee, Sook Young Lee, Suk Joong Yong, Kwang Ha Yoo, Soo Taek Uh, Ramón Agüero Balbín, David Ramos Barbón, Álvar Agustí García-Navarro, José Luis Velasco Garrido, Sergi Pascual Guardia, Eduard Monso Molas, Luis De Teresa Parreño, Borja García-Cosio Piqueras, German Peces-Barba Romero, Myriam Calle Rubio, Fernando Sánchez-Toril López, Alicia Marín Tapia, Heidi Martin Braschler, Martin Brutsche, Michael Grob, Jörg Leuppi, Daiana Stolz, Alexander Turk, Nawar Bakerley, Mona Bafadhel, Christopher Brightling, Rekha Chaudhuri, Gourab Choudhury, Graham Devereux, Imran Hussain, Kai Lee, William MacNee, Ravindran Mahadeva, Matthew Masoli, Monica Nordstrom, Manish Patel, Allan Reid, Dinesh Saralaya, Tariq Sethi, Sukh Dave Singh, Anthony G de Soyza, Tom Wilkinson, Alice Turner, Helen Ward, Chandar Abboy, Ivan Ackerman, Idalia Acosta, Arun Adlakha, Bassil Aish, Mohamed Ali, Charles Andrews, Robby Ayoub, Anil Badhwar, Dennis Bassetti, Sherif El Bayadi, Richard Beasley, Shashi Bellam, Jonathan Bernstein, Maria Blahey, Scott Bloom, Eugene Bleecker, Wesley Bray, Johnathan Brewer, Robert Buynak, William Calhoun, Edward Campbell, Anthony Captain, Birjis Chinoy, Kenneth Chinsky, Geoffrey Chupp, Arsenio Columbie, Clinton Corder, Gerard Criner, Humberto Cruz, Edward Cullen, Kevin Deboer, Michael Denenberg, Mark Dransfield, Leonard Dunn, Miles Elmore, David Erb, Faisal Fakih, Gary Ferguson, Charles Fogarty, Mark Freed, Stephen Fritz, David Fuentes, Shariar Cohen-Gadol, Robert Garver, John Given, Luis Ramos Gonez, Raul Ebran Gonzalez, Robert Gordon, Gregory Gottschlich, Donald Graham, David Grant, Gary Greenwald, James Greenwald, Kenneth Haft, Gregory Hammond, Nadia Hansel, Jeffrey Harris, Humberto Hernandez, Marvin Heuer, Albrecht Heyder, David Hill, Willis Holloway, Octavian Ioachimescu, Richard Jackson, Ajay Jain, Nan Jiang, Thomas Kaelin, Adolfo Kaplan, Mitchell Kaye, Akram Khan, Yekaterina Khronusova, Ryan Klein, Joel Kline, Firas Koura, Ritsu Kuno, Ware Kuschner, Jean Claude Labissiere, David Laman Jr, John Lee, Mitchell Lee, Lawrence Levinson, Njira Lugogo, M Mador, Nathaniel Marchetti, Rafael Martinez, Richard Martinez, Peter Mattar, David Maybee, Dennis McGraw, Michael McGuire, Curtis Mello, Aaron Milstone, John Mitchell, Wendy Moore, Timothy Moriarty, Cheta Nand, Brooke Nevins, Ikeadi Ndukwu, Rachel Nisbet, David Nyanjom, Maria Nualart, Thomas O'Brien, Mikhail Palatnik, Gnyandev Patel, Amit Patel, Guido Perez, Christopher Perry, Michael Pfeffer, Krishna Pudi, Marina Raikhel, Murali Ramaswamy, Joe Ramsdell, Donato Ricci, Gary Richmond, Eugene Ryan, Fadi Saba, Boris Sagalovich, C Andrew Schroeder, Timothy Scialla, Frank Sciurba, Amit Shah, Nirav Shah, Zeeshan Shaikh, Akhtar Siddiqui, Barry Sigal, Thomas Siler, Howard Silverboard, William Sims, Clyde Southwell, Selwyn Spangenthal, Peruvemba Sriram, James Stocks, Tony Su, John Suen, Robert Sussman, Horia Tatu, Antonio Terrelonge, Alan Thomas, Mario Torres, Rodolfo Trejo, Miguel Trevino, Banks Turner, Manuel Villareal, Janine Vintch, Neal Warshoff, Jan Westerman, Philip Wexler, Thomas Yunger, Amir Zeki, Mariano Fernandez Acquier, Norma Aramayo, German Arce, Juan Belloni, Víctor Cambursano, Carlos De La Vega, Fernando Rodriguez Chariarse, Pedro Elias, Marcelo Fernández, Ana Lopez, Andrea Medina, María Otaola, Maria Salazan Saez, Maria De Salvo, Fernando Scherbovsky, Ana Stok, Jorge Taborda, Alberto Tolcachier, Fernando Verra, Carlos Victorio, Rita Gisela Delgado Vizcarra, Philip Bardin, Peter Bremner, Martin Phillips, John Upham, Peter Wark, Antoine Bolly, Alain Delobbe, Peter Driesen, Eduard Janssens, Wim Janssens, Olivier Michel, Bernard Vandooren, Martti Antila, Jussara Fiterman, Carlos Fritscher, Jorge Hetzel, Jose Jardim, Waldo De Mattos, Rafael Martins, Maria Eunice De Oliveira, Andreia Pez, Maria Sales, Rafael Stelmach, Priscila Wolff, Svetla Andreeva, Reneta Antonova, Ana Dancheva, Yuliya Ivanova, Slavcho Ivanov, Hristo Metev, Iveta Naydenova, Tatyana Petkova, Galina Petrova, Kostadinka Sotirova, Mariyana Stoyanova, Rumen Tiholov, Iliyana Valkanova, Oleg Yakov, Rosa Feijoo, Juana Pavie, Patricia Schönffeldt, Absalon Silva, Victor Martinez, David Espinosa, Alejandro Londono, Dora Molina, Gonzalo Prada, Andrés Rico, Gregorio Sanchez Vallejo, Alvaro Urbina, Ana Vanegas, Maria Villegas, Josip Aralica, Gordana Stjepanovic, Vibeke Backer, Uffe Bødtger, Christian Meyer, Læge Sven Nielsen, Anders Loekke Ottesen, Ingrid Titlestad, Nathalie Bautin, Arnaud Bourdin, Pascal Chanez, Francis Couturaud, Antoine Cuvelier, Gilles Devouassoux, Pierre-Olivier Girodet, Jean-François Muir, Jean-Louis Pépin, Alain Proust, Azzedine Yaici, Yochai Adir, Gershon Fink, Zvi Fridlender, Gabriel Izbicki, Mordechai Kramer, Yehuda Schwartz, Juan Moreno Hoyos Abril, Ricardo Campos Cerda, Efraín Montaño Gonzalez, Ricardo Ramirez Terrones, Rodolfo Posadas Valay, Alejandra Ramirez-Venegas, Paul Dawkins, Syed Hussain, Benedict Brockway, John Richmond, Colin Helm, Catherina Chang, Jørn Ahlqvist, Terje Tollåli, Tadeusz Tomala, Socorro Castro, William Chavez, Octavio Cubas, Rolando Estrella, Efrain Felix, Ronal Gamarra, Alfredo Guerreros, Alberto Matsuno, Danilo Salazar, Miguel Tsukayama, Albert Albay Jr, Teresita Aquino, Tito Atienza, Joven Roque Gonong, Ronnie Samoro, Joel Santiaguel, Beata Asankowicz-Bargiel, Ewa Pisarczyk-Bogacka, Renata Bijata-Bronisz, Marta Chełmińska, Małgorzata Dobryniewska, Anna Olech-Cudzik, Tomasz Fijołek, Krzysztof Filipek, Agata Kot, Bożena Kucińska, Krzysztof Lis, Elżbieta Rybicka-Liszewska, Marzenna Tarnowska-Matusiak, Robert Mróz, Piotr Napora, Wojciech Naumnik, Artur Niemiec, Władysław Pierzchała, Grzegorz Przybylski, Katarzyna Styka, Danuta Wrońska, Branislava Milenkovic, Dobrivoje Novkovic, Matijaz Flezar, Niksa Segota, Snezana Ulcar Kostic, Albert Klobucar, Leif Bjermer, Dan Curiac, Christer Janson, Pekka Koskinen, Bo Lundback, Åke Olsson, Shih-Lung Cheng, Ming-Lin Ho, Jeng-Yuan Hsu, Wu-Huei Hsu, Ping-Hung Kuo, Chin-Chou Wang, Yu-Feng Wei, Kuang-Yao Yang, Watchara Boonsawat, Somchai Chantarothorn, Warangkana Keeratichananont, Kittipong Maneechotesuwan, Kanok Pipatvech, Piamlarp Sangsayunh, Sibel Arinc, Sermin Borekci, Arzu Kaner Erturk, Filiz Kosar, Hakan Gunen, Ismail Hanta, Pinar Akin Kabalak, Tunc Alp Demir, Sibel Nayci, Serir Aktogu Ozkan, Abdullah Sayiner, Esra Uzaslan, Viktor Blazhko, Volodymyr Gavrysyuk, Olena Golub, Liudmyla Iashyna, Tetiana Ilashchuk, Volodymyr Koshlia, Olena Krakhmalova, Vitali Kryvenko, Lesia Kuryk, Olena Levchenko, Yuriy Mostovoy, Mykola Ostrovskyy, Tetyana Pertseva, Olena Piura, Nadiya Rudnytska, Ganna Stupnytska, Nataliia Velychko, Oleh Yakovenko, Lilia Rodriguez Ables, Roger Abrahams, Bassil Aish, Jose Alvarez, Fernando Arencibia, Chander Arora, Samir Arora, Francis Averill, Kwabena Ayesu, Stephen Basheda, Steven Bauer, Jose Bautista, Matthew Beacom, Richard Beasley, Hernando Bernal, Subodh Bhuchar, J'Cinda Bitters, John Burk, Elizabeth Burkett, James Cain, Robert Call, Christopher Chappel, Bartolome Celli, Tom Christensen, Jeremy Cole, Jerome Daniel, Nguyen Dang, Enrique Davis, Samuel Deleon, Robert DeLuca, Ernesto Diaz, Anthony DiMarco, Calvin Dixon, Ankur Doshi, Hugh Durrence, Alain Eid, John Elsen, Herbon Fleming, May Flores, Charles Fogarty, Scott Franczek, Stephen Fritz, Gregory Funk, Stuart Garay, Bernard Garcia, Luis Ramos Gonez, Gregory Gottschlich, Joseph Graif, Carl Griffin, Yamirka Duardo Guerra, David Headley, Mitzie Hewitt, Susan Hole, Robert Holladay, Ira Horowitz, Yu-Luen Hsu, Jonathan Ilowite, Stephen Jones, Ravindra Kashyap, Edward Kerwin, Ahtaram Khan, Nicole Kimzey, James Krainson, Flory Kreutter, Kannappan Krishnaswamy, Shahrukh Kureishy, Albert Lai, Alex Lechin, Daria Lee, Marcus Lee, Williams Leeds, Joseph Lillo, Edward Lisberg, Lawrence Madoff, Narendra Maheskwari, Mujibur Majumder, Sashi Makam, Douglas Mapel, Matthew Mardiney, Jennifer Martin, David Maybee, Isaac Melamed, Elvin Mendez, Stuart Millstone, Joseph Montes, Lee Morrow, Frank Murphy, Dany Obeid, France Occy, Godson Oguchi, Juan Ortiz, Francisco Padron, Ward Paine, James Pearle, Enrique Pelayo, Vandely Perez, David Pham, Carlos Piniella, Kevin Pritchett, Padmashri Rastogi, Stephen Ryan, Syed Rehman, Jackson Rhudy, Eustace Riley, James Riser, Clifford Risk, Emory Robinette, Christopher Roney, Gary Ruoff, David Russian, Mercedes Samson, Jay Sandberg, Jose Santiago, William Sargeant, Alan Schecter, Frank Sciurba, Jeffrey Scott, Ilia Segal, Sudhir Sehgal, Frederic Seifer, Sudhir Sekhsaria, Richard Sellman, Paul Shapero, Jeffrey Shea, Lawrence Sher, John Sibille, Jawed Siddiqui, William Sims, Toniya Singh, Deren Sinkowitz, Denise Smyth, Daniel Soteres, Daniel Sousa, Ralph Steele, Thomas Stern, Jose Suarez, Sever Surdulescu, Ricardo Tan, Tonny Tanus, Raymond Tidman, Aurelio Torres-Consuegra, Barry Troyan, John Updegrove, Sanjay Vadgama, Armando Pineda-Velez, Eduardo Viera, Andrew Wachtel, Ralph Wade, Jimin Wang, Dave Webster, Paul Weinberg, Terry Wells, Jeffrey White, Bram Wieskopf, Hugh Windom, Patrick Wright, David Wyatt, Bassam Yousef, Zahid Zafar, Chau Ngo, Huong Le, Lan Nguyen, Thanh Nguyen, Nhung Nguyen

Subjects
Male, [SDV]Life Sciences [q-bio], 030204 cardiovascular system & hematology, Anti-asthmatic Agent, law.invention, Pulmonary Disease, Chronic Obstructive, Leukocyte Count, chemistry.chemical_compound, 0302 clinical medicine, Randomized controlled trial, law, Monoclonal, Receptors, Medicine, Anti-Asthmatic Agents, 030212 general & internal medicine, Humanized, COPD Exacerbations, benralizumab, clinical trials, COPD, Subcutaneous, General Medicine, Middle Aged, anti–IL-5Rα, Benralizumab, Pulmonary Disease, Chronic Obstructive/drug therapy, [SDV] Life Sciences [q-bio], Female, Antibodies, Monoclonal, Humanized/administration & dosage, Chronic Obstructive, Benralizumab COPD exacerbations, Injections, Subcutaneous, Socio-culturale, Aged, Antibodies, Monoclonal, Humanized, Double-Blind Method, Eosinophils, Humans, Patient Acuity, Receptors, Interleukin-5, Antibodies, chronic obstructive pulmonary disease, Injections, Pulmonary Disease, 03 medical and health sciences, Phase III, Anti-Asthmatic Agents/administration & dosage, In patient, business.industry, Eosinophils/metabolism, medicine.disease, Clinical trial, Receptors, Interleukin-5/antagonists & inhibitors, chemistry, Multicenter study, randomized controlled trial, Immunology, Interleukin-5, business
Abstract

BACKGROUND: The efficacy and safety of benralizumab, an interleukin-5 receptor alpha-directed cytolytic monoclonal antibody, for the prevention of exacerbations in patients with moderate to very severe chronic obstructive pulmonary disease (COPD) are not known.METHODS: In the GALATHEA and TERRANOVA trials, we enrolled patients with COPD (at a ratio of approximately 2:1 on the basis of eosinophil count [≥220 per cubic millimeter vs. RESULTS: In GALATHEA, the estimates of the annualized exacerbation rate were 1.19 per year (95% confidence interval [CI], 1.04 to 1.36) in the 30-mg benralizumab group, 1.03 per year (95% CI, 0.90 to 1.19) in the 100-mg benralizumab group, and 1.24 per year (95% CI, 1.08 to 1.42) in the placebo group; the rate ratio as compared with placebo was 0.96 for 30 mg of benralizumab (P = 0.65) and 0.83 for 100 mg of benralizumab (P = 0.05). In TERRANOVA, the estimates of the annualized exacerbation rate for 10 mg, 30 mg, and 100 mg of benralizumab and for placebo were 0.99 per year (95% CI, 0.87 to 1.13), 1.21 per year (95% CI, 1.08 to 1.37), 1.09 per year (95% CI, 0.96 to 1.23), and 1.17 per year (95% CI, 1.04 to 1.32), respectively; the corresponding rate ratios were 0.85 (P = 0.06), 1.04 (P = 0.66), and 0.93 (P = 0.40). At 56 weeks, none of the annualized COPD exacerbation rate ratios for any dose of benralizumab as compared with placebo reached significance in either trial. Types and frequencies of adverse events were similar with benralizumab and placebo.CONCLUSIONS: Add-on benralizumab was not associated with a lower annualized rate of COPD exacerbations than placebo among patients with moderate to very severe COPD, a history of frequent moderate or severe exacerbations, and blood eosinophil counts of 220 per cubic millimeter or greater (Funded by AstraZeneca [GALATHEA and TERRANOVA] and Kyowa Hakko Kirin [GALATHEA]; GALATHEA and TERRANOVA ClinicalTrials.gov numbers, NCT02138916 and NCT02155660.).

Published
2019

13. Designing a Collaboration Platform for Electricity Consumer Councils

Author

Maria Gilda P. Esteves, Luiz Oliveira, Rafael Ris-Ala Jose Jardim, Jano Moreira de Souza, Rubens Rosental, Carlos Gomes de Oliveira, and Nivalde José de Castro

Subjects
050101 languages & linguistics, Collaborative software, business.industry, Computer science, 05 social sciences, ComputingMilieux_LEGALASPECTSOFCOMPUTING, 02 engineering and technology, Underdevelopment, 0202 electrical engineering, electronic engineering, information engineering, 020201 artificial intelligence & image processing, 0501 psychology and cognitive sciences, Electricity, Marketing, business
Abstract

Worldwide, the electricity sector has undergone radical changes with the emergence of new technologies that expand possibilities. In such a dynamic environment, the sector's regulatory and supervisory activities became major challenges. In this article, we present a case study on the collaborative design of a digital platform for learning, accessing information and fostering the collaboration between distributors, the regulatory agency and electricity consumer councils in Brazil. A series of national surveys were conducted with industry authorities, experts, representatives of electricity distributors and representatives of final consumers. Finally, we present the results of these surveys, which allowed the derivation of primary requirements for the design of the collaboration platform that is under development.

Published
2019

14. Impact of Bronchodilator Use on the Prevalence of COPD in Population-Based Samples

Author

Rogelio Pérez-Padilla, Pedro Curi Hallal, Juan Carlos Vázquez-García, Adriana Muiño, María Máquez, María Victorina López, María Montes de Oca, Carlos Tálamo, Gonzalo Valdivia, Julio Pertuzé, Jose Jardim, Ana Maria B. Menezes, and null On behalf of the PLATINO group

Subjects
Adult, Male, Pulmonary and Respiratory Medicine, Spirometry, medicine.medical_specialty, Percentile, medicine.drug_class, Vital Capacity, Population, Asymptomatic, Pulmonary Disease, Chronic Obstructive, FEV1/FVC ratio, Forced Expiratory Volume, Internal medicine, Bronchodilator, Epidemiology, Prevalence, medicine, Humans, education, Aged, COPD, education.field_of_study, medicine.diagnostic_test, business.industry, Age Factors, Urban Health, Middle Aged, respiratory system, medicine.disease, Bronchodilator Agents, respiratory tract diseases, Latin America, Physical therapy, Female, medicine.symptom, business, circulatory and respiratory physiology
Abstract

The aim of this study was to describe the impact of using bronchodilators on the prevalence of Chronic Obstructive Pulmonary Disease in a population-based survey (Platino study). A cluster sampling of subjects 40 years of age or older, representative of the metropolitan areas of 5 Latin American cities (Sao Paulo, Mexico, Montevideo, Santiago and Caracas) was chosen. Spirometry according to ATS standards was done before and after inhalation of 200 micrograms of salbutamol in 5183 subjects. Prevalences of airflow obstruction were estimated using different criteria, in tests done before and after bronchodilator use, and with reference values for pre- or post-bronchodilator use. Bronchodilator testing reduced the overall prevalence of FEV(1)/FVC%0.70 from 21.7% to 14% (35%). In the group with FEV(1)/FVC0.70 after bronchodilator use, 21% were asymptomatic from the respiratory point of view, and lacked significant adverse exposures. Subjects below the 5th percentile for FEV(1)/FVC and FEV(1)/FEV(6) were fewer than those with FEV(1)/FVC0.70, especially among the elderly. More subjects are below the 5th percentile of FEV(1)/FVC and FEV(1)/FEV(6) using reference values for tests after bronchodilator use than using the reference values determined without bronchodilator testing. Testing after bronchodilator use reduces the prevalence of airflow obstruction from 32 to 39% depending on the definition used. In addition, the subjects who were still obstructed after bronchodilator use were the ones who showed more respiratory symptoms and exposure to tobacco and other smokes and dusts, than subjects with reversible obstruction, suggesting an increased specificity for COPD.

Published
2007

15. Ambiente e saúde na cidade de Manaus: percepção de moradores (estudantes do ensino médio) sobre degradação ambiental e doenças infectoparasitárias

Author

Dayson Jose Jardim-Lima, Sueli Angelo Furlan, Ligia Vizeu Barrozo, Jose Bueno Conti, Paulo Roberto Moraes, and Helena Ribeiro

Abstract

O presente estudo possui o objetivo de analisar a distribuição espacial da percepção ambiental de moradores (estudantes do ensino médio) da cidade de Manaus sobre doenças infectoparasitárias relacionadas à degradação ambiental, a partir de uma abordagem ecossistêmica em geografia da saúde. Especificamente de (1) investigar a distribuição espacial da ocorrência de doenças infecciosas e parasitárias relacionadas à degradação ambiental, desflorestamento, poluição do solo e hídrica, na cidade de Manaus; (2) analisar e interpretar o conhecimento de estudantes sobre medidas de prevenção e controle da degradação ambiental urbana e sua relação com a saúde humana; (3) analisar o conhecimento de estudantes sobre medidas de prevenção e controle das doenças infecciosas e parasitárias; e (4) relacionar à percepção dos estudantes a espacialidade urbana da cidade de Manaus. A cobertura vegetal é o primeiro recurso natural a sofrer os efeitos do assentamento humano sem planejamento na cidade de Manaus, seguido da degradação do solo e dos recursos hídricos. Consequentemente, resulta na produção de várias doenças relacionadas a esta degradação ambiental, tais como Dengue, Malária, Febre tifóide, Leptospirose, Hepatite (VHA) e Tétano acidental. Sob autorização de pesquisa Nº 011.37640.2012/SEDUC-AM, foi aplicado um questionário quali-quantativo estruturado à 241 estudantes moradores de todas as zonas administrativas Norte, Sul, Leste, Oeste, Centro-Sul e Centro-Oeste e que assinaram o Termo de Consentimento Livre e Esclarecido. O maior número de casos notificados foi de Malária (92,74%), Hepatites (4,13%) com dados agrupados para VHA, VHB e VHC, Dengue (2,75%) e representaram menos que 1% os casos de Febre Tifoide, Leptospirose e Tétano Acidental prevalentes em Manaus no ano 2009. A Dengue, Febre Tifoide, Hepatite A, Leptospirose e Tétano Acidental possuem relação com as precárias condições de saneamento ambiental e degradação do solo (com resíduos sólidos domésticos e perfuro-cortantes) e de águas superficiais e de consumo contaminados. A Malária possui relação com o desflorestamento em ocupação irregular do solo (invasões) na cidade de Manaus. Os moradores possuem idade média de 19,89 anos (mediana 19 anos; desvio padrão de 3,33), sendo 43,15% do gênero masculino e 56,85% feminino. A pesquisa abrange 35 bairros (56%) dos 63 oficialmente reconhecidos pela Prefeitura de Manaus. Os moradores da cidade percebem o lugar vivido, o saneamento ambiental, o meio ambiente, degradação ambiental e a relação com a produção de doenças infectoparasitárias, a prevenção, o risco de adoecer e de morrer, de forma diferente entre as zonas Norte, Sul, Leste, Oeste, Centro-Sul e Centro-Oeste. O sentimento de pertencimento ou não ao bairro onde moram, a ausência de serviços públicos importantes para melhorar a qualidade ambiental e de vida no bairro, dificultam criar elos de identidade entre o morador e a cidade Manaus. The present study has the objective to analyze the spatial distribution of environmental perception of residents (high school students) in the city of Manaus on diseases infectious parasitic diseases related to environmental degradation, from an ecosystem approach in geography of health. Specifically , (1) investigate the spatial distribution of the occurrence of infectious and parasitic diseases related to environmental degradation, deforestation, pollution of soil and water, in the city of Manaus, Brazil; (2) analyze and interpret the knowledge of students on measures for the prevention and control of environmental degradation urban and its relationship with health human; (3) analyze the knowledge of students on measures for the prevention and control of infectious and parasitic diseases; and (4) relate to the perception of the students the spatiality city of Manaus. The cover crop and the first natural resource to suffer the effects of human settlement without planning in the city of Manaus, followed by degradation of soil and water resources. Consequently, results in the production of various diseases related to this environmental degradation, such as dengue, malaria, typhoid fever, Leptospirosis, hepatitis (HAV) and tetanus. Under authorization of research Nº 011.37640.2012/SEDUC-AM, a questionnaire was applied quali-quantitative structured to 241 students inhabitants of all administrative areas North, South, East, West, South Central and Midwest, and that signed the Free and Informed Consent Form. The largest number of cases reported was of Malaria (92,74 % ), hepatitis (4.13 %) with data grouped for HAV, HBV and HCV, Dengue (2.75 %) and accounted for less than 1% of the cases of typhoid fever, leptospirosis and tetanus prevalent in Manaus in the year 2009. The Dengue, typhoid fever, hepatitis A, leptospirosis and tetanus have relation with the precarious conditions of sanitation environmental degradation and the ground (with household waste and needles) and surface waters and consumption of contaminated. The Malaria has relation with the deforestation in irregular occupation of the soil (\"invasion\") in the city of Manaus. residents have average age of 19.89 years (median 19 years; standard deviation of 3.33), being 43,15% of the male gender; 56.85% female. The survey covers 35 districts (56 %) of the 63 officially recognized by the city of Manaus. The inhabitants of the city perceive the place lived, the environmental sanitation, the environment, environmental degradation and the relationship with the production of parasitic diseases, prevention, the risk of becoming ill and dying, differently between the areas North, South, East, West, South and Center-west . The feeling of belonging or not the neighborhoods where they live, the absence of public services important to improve the quality of the environment and of life in the neighborhood, hinder create Links of identity between the resident and the city Manaus.

Published
2015

17. Oral motor performance in spastic cerebral palsy individuals: are hydration and nutritional status associated?

Author

Maria Teresa, Santos, Renato, Batista, Elisangela, Previtali, Adriana, Ortega, Oliver, Nascimento, and Jose, Jardim

Subjects
Male, Adolescent, Drinking, Nutritional Status, Body Mass Index, Eating, Hemoglobins, Young Adult, Humans, Child, Saliva, Serum Albumin, Mouth, Platelet Count, Cerebral Palsy, Osmolar Concentration, Transferrin, Blood Proteins, Water-Electrolyte Balance, Deglutition, Hematocrit, Motor Skills, Erythrocyte Count, Mastication, Female, Serum Globulins, Secretory Rate
Abstract

Previous studies reported alterations in salivary parameters in cerebral palsy (CP) individuals; however, none of these considered oral motor performance as possibly responsible for these conditions. The aim of this study was to investigate the influence of oral motor performance on the nutritional status and salivary parameters in individuals with CP.Forty-three individuals aged 11-19 years-old, with spastic CP were included in this study. Oral motor performance was evaluated using the Oral Motor Assessment Scale, which classified the individuals into two groups: subfunctional or functional. Unstimulated saliva was collected and the flow rate was calculated (ml/min). Salivary osmolality was measured using a freezing point depression osmometer. Blood samples were collected to evaluate complete blood count, total protein, albumin/globulin ratio and transferrin levels.The subfunctional (n = 21) and the functional group (n = 22) did not differ regarding sex (P = 0.193), however the functional group was older (P = 0.023) and had a higher mean BMI (P0.001). The subfunctional CP group presented a reduction in salivary flow rate (36.4%) (P0.01) and an increase in salivary osmolality (35.5%) (P0.001) compared to the functional group. Slightly lower values for red blood cells (millions/mm(3) ) (P0.001), hemoglobin (g/dl) (P0.009), hematocrit (%) (P = 0.001), number of platelets (N/mm(3) ), total protein (g/dl) and albumin/globulin ratio (P = 0.003 and P = 0.036, respectively) were determined for the subfunctional group, but within the normal range of normality.Cerebral palsy individuals appear to present impaired adequate hydration due to compromised oral motor performance.

Published
2011

18. Influence of N-acetylcysteine on chronic bronchitis or COPD exacerbations: a meta-analysis

Author

Mario Cazzola, Luigino Calzetta, Clive Page, Josè Jardim, Alexander G. Chuchalin, Paola Rogliani, and Maria Gabriella Matera

Subjects
Diseases of the respiratory system, RC705-779
Abstract

In order to clarify the possible role of N-acetylcysteine (NAC) in the treatment of patients with chronic bronchitis and chronic obstructive pulmonary disease (COPD), we have carried out a meta-analysis testing the available evidence that NAC treatment may be effective in preventing exacerbations of chronic bronchitis or COPD and evaluating whether there is a substantial difference between the responses induced by low (≤600 mg per day) and high (>600 mg per day) doses of NAC. The results of the present meta-analysis (13 studies, 4155 COPD patients, NAC n=1933; placebo or controls n=2222) showed that patients treated with NAC had significantly and consistently fewer exacerbations of chronic bronchitis or COPD (relative risk 0.75, 95% CI 0.66–0.84; p

Published
2015
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19. The ekphrastic dimension in E.T.A. Hoffmann s short stories: a propaedeutic study for an approach to metamusical narratives

Author

Ruthner, Simone Maria, Nuñez, Carlinda Fragale Pate, Castro, Antonio Jose Jardim e, and Kretschmer, Johannes

Subjects
Princípio serapiôntico, Serapiontic principle, Arte na literatura, Literatura metamusical, Hoffmann, E. T. A. (Ernst Theodor Amadeus), 1776-1822 - Crítica e interpretação, Contos alemães - História e crítica, Ekphrasis, E.T.A. Hoffmann, LINGUISTICA, LETRAS E ARTES::LETRAS::LITERATURA COMPARADA [CNPQ], Análise do discurso narrativo, Intermediality, Metamusical Literature, Pathosformel, Écfrase, Intermidialidade
Abstract

Submitted by Boris Flegr (boris@uerj.br) on 2021-01-05T15:15:30Z No. of bitstreams: 1 Simone Maria Ruthner_Dissertacao.pdf: 2352564 bytes, checksum: 161e13c2770fc7d52549b27b294df788 (MD5) Made available in DSpace on 2021-01-05T15:15:30Z (GMT). No. of bitstreams: 1 Simone Maria Ruthner_Dissertacao.pdf: 2352564 bytes, checksum: 161e13c2770fc7d52549b27b294df788 (MD5) Previous issue date: 2016-05-13 This study of the ekphrastic dimension in E.T.A. Hoffmann s short stories deals with the relationship between the arts, namely, the links between painting, music and literature, in the process of creating his musical narratives. Musician, writer, critic and musical aesthete, as well as a jurist, the German author from Königsberg was also a painter. Ekphrasis has its origins in ancient oratory, and eventually found application in the plastic arts, especially painting, renewing its relevance for literature; it can also be identified in music, which makes it a consequential intermedial device in that author s work. Organized in three parts, this research seeks to survey the interpenetration of music and painting in Hoffmann s literary works, as well as the critical-theoretical intuitions therein. The first chapter presents an artistic-biographical topography of Hoffmann, showcasing his activities in painting and music. The second chapter emphasizes theoretical approaches dealing with merging borders in poetical representation, namely, the concepts of ekphrasis, intermediality, Pathosformel and the Serapiontic principle. Among the various theorists at the foundations of this work are Lessing, Clüver, Schröter, Bruhn, Mai Al-Nakib, Kumbier and Warburg, drawing from Tomlinson s theories, and put to dialogue with Hoffmann s own theories. Finally, the third chapter examines the ekphrastic device in two short stories, Die Fermate (The Fermata) and Rat Krespel (Counselor Krespel). These analyses afford the conclusion that the ekphrastic topos leads to the idea of metamusical narrative. O estudo da dimensão ecfrástica nos contos de E.T.A. Hoffmann contempla a relação entre as artes, nomeadamente, as articulações entre pintura, música e literatura, no processo criativo de suas narrativas musicais . Músico, escritor, crítico e esteta musical, além de jurista, o escritor alemão de Königsberg também se dedicou à pintura. A écfrase tem a sua origem na antiga oratória, de onde se estende às artes plásticas, em especial à pintura, revigora sua relevância para a literatura e pode ser identificada também na música, o que faz dela um dispositivo intermidial fecundo, na obra deste autor. A pesquisa, que visa dimensionar a interpenetração da música e da pintura na criação literária hoffmanniana, bem como as intuições teórico-críticas nela presentes, se organiza em três partes. O primeiro capítulo apresenta uma topografia artístico-biográfica de Hoffmann, colocando em foco as suas atividades na pintura e na música. O segundo capítulo apresenta as teorias que norteiam o cruzamento das fronteiras nas representações poéticas, a saber: os conceitos de écfrase, intermidialidade, Pathosformel e o Princípio serapiôntico. Dentre os vários teóricos que embasam este estudo, destacam-se Lessing, Clüver, Schröter, Bruhn, Mai Al-Nakib, Kumbier e Warburg, através das teorias de Tomlinson, colocadas em diálogo com as teorias do próprio Hoffmann. O terceiro capítulo testa o dispositivo da écfrase nos contos Die Fermate (A fermata) e Rat Krespel (Conselheiro Krespel), cujas análises resultam na constatação de que o topos ecfrástico leva à ideia de narrativa metamusical.

Published
2016

20. Sobre harmonia: uma proposta de perfil conceitual

Author

Fabio Adour da Camara, Eduardo Fleury Mortimer, Ana Maria Rabelo Gomes, Heloisa Faria Braga Feichas, Rafael dos Santos, and Antonio Jose jardim e Castro

Subjects
Educação, Harmonia, Música
Abstract

O tema dessa pesquisa é um dos parâmetros mais importantes da Música Ocidental: a Harmonia. A Harmonia estuda a combinação simultânea de notas, o que produz os chamados acordes, e investiga as diversas possibilidades de concatenação desses acordes. O material bibliográfico sobre o assunto é extenso, porém sofre de um marcante desencontro: as publicações oriundas do universo da Música Eruditageralmente desconsideram o repertório popular mais ou menos recente; e as publicações provenientes do mundo musical popular, por sua vez, não levam em conta os recursos há muito estabelecidos pela tradição histórica do estudo de Harmonia. Tal descompassovem produzindo uma série de incongruências teóricas, conceituais e epistemológicas. Estando inseridos num meio acadêmico tradicional e vivendo um momento em que a Música Popular definitivamente adquire o direito sobre uma parcela desse espaço, começamos a pensar na possibilidade de lançar mão da noção de Perfil Conceitual, umaparato educacional que prevê a convivência de diversas conceituações sobre um mesmo tema, as quais são chamadas de Zonas Conceituais. Conforme percebemos que outras visões sobre Harmonia coexistem com os dois caminhos teóricos acima aludidos e como esse modelo didático também prevê a conscientização quanto aos contextos elimites de aplicação de cada ponto de vista, resolvemos propor um Perfil Conceitual de Harmonia. Primeiro procuraremos definir e caracterizar esses domínios conceituais já existentes; em segundo lugar, faremos a sugestão de uma nova zona, que aproveita, revisa, critica e integra as ferramentas dos outros âmbitos epistemológicos, além de criarnovos aparatos explicativos; e, por fim, realizaremos uma análise de discurso de um contexto de ensinoaprendizagem que ministramos e filmamos. Com esse material de campo temos a intenção de corroborar o Perfil proposto e de apontar futuros caminhos didáticos. Também empregaremos uma ferramenta analítica oriunda do universoeducacional que valoriza o diálogo e a contraposição de diversas perspectivas, permitindo uma avaliação de dados congruente com o caráter polissêmico da noção de Perfil Conceitual. The present research is about one of the most basic elements of Western music: harmony. Harmony is the study of the simultaneous combination of sounds, the socalled chords, and investigates the myriad possibilities of organizing them. Despite all the number and variety of publications on harmony, there still is an important, not yet bridged gap: publications that originate in the classical music world do not include more or less recent popular repertoire, and publications that originate in the popular music world do not include so many materials that have been long established by the historic tradition of harmony studies. This gap has been producing much theoretical, conceptual and epistemological incongruence. Given the growing space allotted to popular music inthe academic sphere, and our need to adjust the traditional music academe to this new reality, we deemed useful to work with the notion of conceptual profile, an educational device that allows for the cohabitation of different concepts of a subject. We call the latter conceptual zones. As we realized that other views on harmony coexist with thetwo theoretical trends mentioned above, and because our didactic model lays out the comprehension of the contexts and practical limitations of all views, we propose a conceptual profile of harmony. We start off our work by defining and describing such already existing conceptual domains. Then we propose a new zone which takes advantage of, revises, criticizes and integrates the available tools of other epistemological realms, and also creates new explanatory devices. And finally we perform a discourse analysis of a live teaching-learning situation that we enacted and filmed. This field material is then used to defend the profile that we propose and suggest didactic procedures for the future. In order to achieve our goal we use an educational analytical tool which values dialogue and the comparison of different perspectives, so as to interpret data according to the polysemic character of the notion of conceptual profile.

Published
2008

21. A música habita a linguagem teoria da música e noção de musicalidade na poesia: teoria da música e noção de musicalidade na poesia

Author

Flavio Terrigno Barbeitas, Maria Antonieta Pereira, Leda Maria Martins, Rosangela Pereira de Tugny, Werner Aguiar, and Antonio Jose jardim e Castro

Subjects
Quadro epistemológico, Música e literatura, Poesia História e crítica, Música e linguagem, Teoria musical, Linguagem poética, Musica Filosofia, Musicologia, Logocentrismo
Abstract

A tese propõe uma discussão da relação entre música e linguagem, colocando em perspectiva crítica a tendência contemporânea de classificação apriorística da música, no quadro epistemológico, como um sistema semiótico . De um lado, acentuado o fato de a linguagem verbal e a música compartilharem a sonoridade, o trabalho busca evidenciar elementos que podem ser qualificados como musicais e que atuam na linguagem ainda antes de se integrarem na engrenagem de significação e codificação, como é o caso da voz. De outro, explorando a noção de musicalidade que permeia a teoria da poesia, a tese indica que o valor musical de um poema costuma justamente estar ligado à capacidade de a linguagem poética escapar à lógica férrea da representação e da significação unívoca, em proveito da exploração da ambiguidade e do potencial de movimento da palavra, com suas múltiplas direções e sentidos.Por essa dupla via, questiona-se exatamente o primado da representação e da significação (logocentrismo) - pelo qual a música foi progressivamente relegada a um plano secundário na classificação ocidental do conhecimento - e discutem-se as bases em que historicamente se estabeleceu a chamada teoria da música.

Published
2007

22. A disciplina Harmonia nas escolas de música: objetivos e limites de uma prática pedagógica

Author

Eduardo Campolina Viana Loureiro, Angela Imaculada L de F Dalben, Antonio Jose jardim e Castro, and Luciano Mendes de Faria Filho

Subjects
Prática pedagógica, Educação, Harmonia (Musica) Instrução e ensino, Musica Analise, apreciação, Escolas de música, Musica Estudo e ensino, Harmonia (Musica)
Abstract

O presente trabalho tem como objetivo refletir sobre a prática de ensino de Harmonia, e foi construído a partir de duas perguntas principais: ensinar Harmonia, para quê?; ensinar Harmonia, como? Para respondê-las partiu-se de uma análise documental e de entrevistas realizadas com seis professores de Harmonia em atividade atualmente. A análise documental foi efetuada sobre 18 obras, selecionadas entre os grandes tratados de Harmonia tradicionais e as publicações mais modestas, elaboradas com objetivos pedagógicos. Foi coberto o período que se estende desde o século XVIII quando Jean Philippe Rameau, fundador da teoria da Harmonia, publica seu Traité d'Harmonie, passando pelos tratados tradicionais europeus do século XIX, pelas teorias surgidas no início do século XX (teoria das funções, utilização do espaço não temperado), chegando aos tratados mais recentes publicados na segunda metade do século XX. Procurou-se discutir e compreender as características, os limites, as vantagens e desvantagens das práticas de ensino que essas obras indicam e possibilitam. Foi discutida mais detidamente a proposta de ensino de Arnold Schoenberg contida em seu Tratado de Harmonia. Nas entrevistas com os professores foram discutidos aspectos considerados pertinentes numa prática de ensino de Harmonia, tais como sua relação com o desenvolvimento da percepção, com a criatividade, com as demais disciplinas de um currículo universitário, com o repertório utilizado em sala de aula. Nas entrevistas com os professores procurou-se estabelecer, sempre que possível, relações com o que foi percebido nas análises do tratados. Espera-se que as reflexões aqui produzidas possam contribuir para ampliar a discussão a respeito do ensino de Harmonia no meio musical. Ce travail prend comme objectif la réflexion sur l'enseignement de l'Harmonie, et a été construit à partir de deux questions principales: enseigner l'Harmonie, pourquoi?; enseigner l'Harmonie, comment? Les réponses partent d'une analyse documentale et d'une série d'interviews réalisées avec six professeurs d'Harmonie en activité actuellement. L'analyse documentale a été effectuée sur 18 oeuvres, selectionnées parmi les grands traités d'Harmonie traditionels et les publications plus modestes, elaborées à des fins pédagogiques. Le travail s'étend du XVIIIème siècle, quand Jean-Philippe Rameau, fondateur de la théorie de l'Harmonie publie son Traité d'Harmonie, en passant par les traités traditionels, publiés en Europe pendant le XIXème siècle, par les théories proposées au début du XXème siècle (la théorie des fonctions, l'utilisation de l'espace non-temperé), jusqu'aux traités plus récents, publiés dans la deuxième moitié du XXème siècle. Nous avons essayé de discuter et de comprendre les caractéristiques, les limites, les avantages et désavantages des practiques d'enseignement indiquées et rendues possibles par ces oeuvres. La proposition d'enseignement d'Arnold Schoenberg, contenue dans son Traité de'Harmonie, a été discuté d'une manière plus détaillée. Dans les interviews avec les professeurs, ont été discutés des aspects considérés comme pertinents dans la pratique d'enseignement de l'Harmonie, tels que sa relation avec le développement de la pérception, avec la creativité, avec les disciplines du curriculum universitaire, avec le répertoire utilisé dans les classes. Dans les interviews ont été établis, dans la mesure du possible, des rapports avec ce que a été perçu dans l'analyse des traités.

Published
2002

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