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BACKGROUND AND AIMS Kidney transplantation (KT) improves survival and quality of life of patients with end-stage renal disease. However, there is still an unbalance between supply and demand for kidneys. To increase the number of available grafts and reduce the waiting list for transplantation, recruitment of older living donors has expanded. This approach remains controversial for several reasons, including the impact of kidney function decline on long-term graft and recipient survival. We aimed to evaluate the impact of living donor (LD) age on recipient graft survival and on graft function decline over time. METHOD This is a Unicenter retrospective observational study that included kidney transplants of LD between 2008 and 2017. Several clinical data were analyzed, including donors’ comorbidities, immunological features of the transplant, induction immunosuppression, number of acute rejections (AR) at the first year, and the graft glomerular filtration rate (eGFR) during the follow-up period. The eGFR was calculated using the CKD-EPI equation. The LDs were classified as young ( The Kaplan–Meier curves and Cox proportional hazards multivariable regression were used for survival analysis and linear mixed regression was used to evaluate the annual slope of recipient eGFR, comparing both groups. RESULTS We observed 210 LD kidney transplants: 86% (n = 181) from young (D The censored recipient graft survival was similar for D Linear mixed regression showed that recipient eGFR from D ≥60 was lower than D CONCLUSION Although the greater eGFR graft decline in the first 12 months and beyond, we demonstrated that kidneys from older living donors did not significantly compromise the censored recipient graft survival. We did not evaluate the age match between donor and recipient, as has been done in other studies, but even so, these results support the importance of increasingly encouraging KT from older living donors. It can improve the quality of life, compared to the time on dialysis and, especially for old candidates, can be the only chance to get transplanted.

BACKGROUND AND AIMS Living donor kidney transplantation (LDKT) is the best treatment for end-stage kidney disease and is associated with better recipient outcomes than deceased donor transplantation. Living kidney donors (LKD), however, seem to be at increased risk of chronic kidney disease (CKD), which mandates a careful selection to reduce the chances of selecting a donor at risk of developing CKD. A predictive model to estimate the 1-year post-donation estimated glomerular filtration rate (eGFR) and risk of CKD was developed from a Toulouse-Rangueil cohort in 2017 [1] and has been shown to have significant correlation to the observed 1-year post-donation eGFR [2]. We aimed to externally validate this predictive tool in a cohort of patients who underwent LDKT at our center. METHOD Retrospective analysis of the 210 LKD at Centro Hospitalar Universitário do Porto from 2008 to 2017. Observed eGFR using CKD-EPI formula at 1-year post-donation was compared with the predicted eGFR using the formula developed in Toulouse-Rangueil. This predictive model is based in pre-donation eGFR and age: Postoperative eGFR (CKD-EPI, mL/min/1.73m2) = 31.71 ± (0.521 × preoperative eGFR)—(0.314 × age). Pearson correlation coefficient was used to estimate correlation between predicted and observed eGFR. Agreement was evaluated by the Bland-Altman plot. Discriminative ability to predict CKD (defined as eGFR RESULTS From 2008 to 2017, 210 LDKT were performed. Six donors were excluded from the study for lacking evaluation of eGFR at 1-year. Mean donor age was 48.1 ± 10.5. Mean pre-donation eGFR was 100.2 ± 14.1 mL/min/1.73 m2. Mean 1-year post-donation observed and predicted eGFR were respectively 70.8 ± 14.5 mL/min/1.73 m2 and 68.8 ± 9.6 mL/min/1.73 m2. Significant correlation (Pearson r = 0.66; P CONCLUSION In this external validation of the formula developed in Toulouse-Rangueil, we found it to have a good correlation, agreement and accuracy for the prediction of the donors 1-year post-donation eGFR. Moreover, a good discriminative ability was also observed with significant sensitivity and specificity, allowing for a pertinent prediction of CKD. This model may be used to assist in the evaluation of potential donors.

BACKGROUND AND AIMS Living donor kidney transplantation (LDKT) provides the best outcomes of all renal replacement modalities, including survival and quality of life. Studies on the association between pre-donation estimated glomerular filtration rate (eGFR) and graft outcomes have yielded inconsistent results. Two eGFR thresholds are generally used to accept or deny a donor (respectively, ≥90 and METHOD This is a unicentric retrospective observational study that included the LDKT pairs submitted to transplant between 2008 and 2017. We gathered clinical data, including donor's comorbidities, immunological features of the transplant, the occurrence of acute rejection episodes in the first year, and graft eGFR during the follow-up period. For statistical purposes, we split the donors in three groups: group 1, with eGFR ≥90 mL/min/1.73 m2; group 2, eGFR RESULTS We studied 210 donor-recipient pairs. The average age at the time of transplant was 48.0 ± 10.6 years for donors and 41.3 ± 13.3 years for recipients. Pre-donation eGFR was 100.1 ± 14.2 mL/min/1.73 m2 and most donors (78%) were in group 1 (eGFR 105.9 ± 9.4 mL/min/1.73 m2). We found two independent predictors of death censored graft failure: the occurrence of rejection episode(s) during the first year (HR: 4.99, CI: 1.44–17.26, P = 0.011) and having a donor from group 3 (HR: 5.14, CI: 1.49–17.75, P 0% (HR: 3.802, CI: 1.387–10.489, P = 0.010) and donor from group 3 (HR: 3.514, CI: 1.087–11.355, P = 0.036). At 1-year after transplant, the recipients from group 1 had a significantly higher eGFR than patients from group 2, but did not differ from group 3 (respectively, 60.8 versus 54.4 [P CONCLUSION This study suggests that in LDKT, when donors’ eGFR is borderline (

Nephrotic syndrome in systemic lupus erythematosus patients with histological evidence of minimal change disease, mesangial proliferation or focal and segmental glomerulosclerosis on light microscopy, represents a distinct clinical entity – lupus podocytopathy. This entity is characterized by a diffuse foot process effacement on electron microscopy and by absence of subepithelial or subendothelial immune -complex deposition. We report the case of a 49 -year -old woman admitted on suspicion of lupus nephritis flare, characterized by nephrotic syndrome and acute kidney injury, whose renal biopsy revealed histological features of lupus podocytopathy. Six months after discharge, under prednisolone and azathioprine, she presented 300 mg/day proteinuria, normal kidney function, without hematuria. A review of the pathogenesis, clinical features, diagnostic criteria, treatment and prognosis of lupus podocytopathy is provided. This case highlights the mounting evidence that lupus podocytopathy encompasses distinct clinical and morphological features, that should be included in the upcoming pathological classification of lupus nephritis.

In peritoneal dialysis (PD), a cloudy dialysate is an alarming finding. Bacterial peritonitis is the most common cause, however, atypical infections and non-infectious causes must be considered. A 46-year-old man presented with asthenia, paraesthesia, foamy urine and hypertension. Laboratory testing revealed severe azotaemia, anaemia, hyperkalaemia and nephrotic-range proteinuria. Haemodialysis was started through a central venous catheter. Later, due to patient preference, a Tenckhoff catheter was inserted. Conversion to PD occurred 3 weeks later, during hospitalization for a presumed central line infection. A month later, the patient was hospitalized for neutropenic fever. He was diagnosed an acute parvovirus infection and was discharged under isoniazid for latent tuberculosis. Four months later, the patient presented with fever and a cloudy effluent. Peritoneal fluid (PF) cytology was suggestive of infectious peritonitis, but the symptoms persisted despite antibiotic therapy. Bacterial and mycological cultures were negative. No neoplastic cells were detected. Mycobacterium tuberculosis eventually grew in PF cultures, despite previous negative molecular tests. Directed therapy was then initiated with excellent response. Thus, facing a cloudy effluent, one must consider multiple aetiologies. Diagnosis of peritoneal tuberculosis is hampered by the lack of highly sensitive and specific exams. Here, diagnosis was only possible due to positive mycobacterial cultures.

Peritonitis is a serious complication in peritoneal dialysis, usually secondary to an infectious cause. Chemical peritonitis is rarer. No case exclusively attributed to vancomycin has been reported in the last 20 years. Data from 4 consecutive patients diagnosed with culture -negative peritonitis following administration of intraperitoneal vancomycin between May and June 2019 were retrospectively recorded. All patients were treated with 2 grams of intraperitoneal vancomycin after a break in aseptic technique and developed a cloudy effluent. No patient was previously known to be allergic to vancomycin. All had a clear dialysate before vancomycin. All developed an elevated leukocyte count in the dialysate. All had sterile cultures. All resumed a clear effluent with less

Arteriovenous fistulas (AVFs) are the first-choice vascular access for most HD patients. Up to 60% of AVFs do not mature adequately, mostly due to stenosis. Surgical and endovascular techniques can rescue up to 80% of these AVFs from primary failure, allowing them to be safely and effectively used in HD, preserving venous capital, and avoiding placement of CVCs and associated complications. This article reviews and summarizes the existing literature, offering a practical approach on early identification, treatment, and monitoring of immature AVFs.

Objectives Knowledge about the impact of coronavirus disease 2019 (COVID-19) on kidney transplant recipients (KTRs) concerning viral shedding and humoral immune response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is limited. The aim of this study is to analyze viral dynamics and the antibody response to SARS-CoV-2 in KTRs with COVID-19 and study their association with clinical data. Materials and methods Consecutive KTRs diagnosed with COVID-19 at our center were evaluated for clinical presentation and outcome; duration of viral shedding and viral burden by reverse transcription-polymerase chain reaction assay cycle threshold; and magnitude of seroconversion to SARS-CoV-2. Results Six KTRs identified with COVID-19 were hospitalized. Presenting symptoms were similar to those in the general population. Four patients had severe disease and, of these, 2 required mechanical ventilation, 4 had acute kidney injury, and 3 had secondary bacterial infections. Immunosuppression was reduced in all patients. Five patients were treated with hydroxychloroquine. No patient required dialysis or died. Patients with severe disease had a longer duration of viral shedding, which lasted more than 40 days, and had IgG antibodies against SARS-CoV-2, which were detected from 3 weeks to as long as 10 weeks after symptom onset. In patients with less severe disease no IgG antibodies where detected between 9 and 14 weeks after symptom onset. Conclusions In our series, KTRs with severe COVID-19 had prolonged viral shedding and a stronger humoral immune response to SARS-CoV-2. These preliminary data need to be confirmed with further studies and over a longer period of time., Highlights • Patients with severe coronavirus disease 2019 have a longer duration of viral shedding. • Prolonged viral shedding persists after clinical resolution and antibodies emerge. • Seroconversion was not detected in moderate disease beyond 9 weeks after infection. • In severe disease, IgG antibodies persist at least until 10 weeks after infection.

En el presente estudio se analizo el impacto del coaching como estrategia formativa del personal encargado de las ventas en la industria hotelera en Mexico. El objetivo fue brindar servicios de calidad y comercializacion a traves del mejoramiento de la formacion y capacitacion del personal responsable de las ventas, brindando estrategias que integren la dimension emocional en el desarrollo humano para proporcionar un servicio de calidad a un precio justo. La metodologia de investigacion consistio en un estudio cuasi-experimental empleando un diseno descriptivo-comparativo, con una muestra de 30 participantes quienes conformaron los grupos control y experimental. Se utilizo la tecnica de muestreo probabilistico estratificado, considerando las funciones del personal, las caracteristicas del hotel y la zona geografica en donde se encuentran. Como instrumentos de investigacion se utilizaron dos cuestionarios, uno con indicadores sociodemograficos y otro basado en indicadores que miden el impacto del coaching en el desempeno laboral, asi como un guion de entrevista. Los resultados se obtuvieron a partir de la comparacion entre las frecuencias obtenidas, de acuerdo a las variables establecidas con y sin coaching . Estos resultados mostraron la relacion positiva de los ejecutivos de ventas que recibieron curso de coaching con las caracteristicas y objetivos que los gerentes solicitaron a los responsables de esta area en sus hoteles. Una importante conclusion es que la capacitacion debe incluir el desarrollo humano como base para realizar su trabajo diario, siempre acompanado de un buen lider que le ayude a desarrollarse personal y profesionalmente de manera integral. Palabras clave: Coaching , desarrollo humano, estrategias de venta, necesidades de la demanda. Abstract This study analyzed the impact of coaching as a strategy for training sales personnel in the hotel industry in Mexico. The aim was to offer quality services and marketing by improving the training and education of sales personnel, providing strategies that integrate the emotional dimension in human development to provide a high-quality service at a fair price. The research methodology consisted of a quasi-experimental study using a descriptive-comparative design, with a sample of 30 participants who comprised the experimental and control groups. The technique of stratified probability sampling was used, considering the functions of the personnel, the characteristics of the hotel and the geographic area where they are located. Two questionnaires were used as research instruments: one with sociodemographic indicators and the other based on indicators that measure the impact of coaching on work performance as well as an interview script. The results were obtained by comparing the obtained frequencies according to the variables established with and without coaching. These results showed the positive relationship of sales executives who underwent the coaching course and the characteristics and objectives that the managers asked of those in charge of this area in their hotels. One important conclusion is that the training must include human development as the foundation for performing daily work, always accompanied by a good leader who aids in personal and professional development in a comprehensive way. Key words: Coaching, human development, sales strategies, demand needs. (Presentado: 20 de abril de 2017. Aceptado: 07 de junio de 2017)

Propósito: A partir de la revisión de la literatura del enfoque socioformativo se identificó el papel central de los problemas del contexto como un aspecto fundamental para lograr el cambio en los procesos de formación actual. Metodología: se realizó una revisión documental empleando la cartografía conceptual como herramienta de investigación a partir de los 8 ejes que la conforman. Principales resultados: los problemas del contexto están conformados por una necesidad y una meta, esto permite orientar la actuación de las personas en una realidad que exige la articulación de saberes. Los problemas d el contexto se confunden con las situaciones problemas, propias del constructivismo, por lo que se identifican las diferencias para asegura r su abordaje en la docencia propuesta desde la socioformación. Discusión: la literatura sobre este tema es un elemento innovador en centros de investigación e instituciones educativas, por ello es importante contar con una metodología que trabaje con los problemas del contexto en las secuencias didácticas que conforman la planificación escolar para trascender en el manejo de contenidos y su aplicación descontextualizada

Estudios recientes dan muestra de la trascendencia del síndrome de burnout, considerado ya una de las “enfermedades profesionales” a nivel mundial. Organismos internacionales se han dado a la tarea de investigar los factores desencadenantes y la afectación psicosocial de los trabajadores en su entorno laboral, sin embargo, entre todos los sectores que han sido analizados, en el docente aún existe un vacío. En el presente estudio, cuyo propósito es el de validar, mediante juicio de expertos, los contenidos de un instrumento de diagnóstico del síndrome de burnout en el contexto actual de los profeso res, se exploran los factores que intervienen para la detección de este padecimiento, tomando como principal referente las características del Maslach Burnout Inventory (MBI), pero con un mayor nivel de análisis y solidez en escenarios mexicanos. Se vali da la concordancia y consistencia de los ítems que evalúan niveles de satisfacción laboral, producto del clima organizacional de la institución educativa, como factores que inciden en la aparición del síndrome de burnout. Se emplea el coeficiente d e con cordancia de W Kendall, para medir el grado de correlación y consistencia interna de las variables entre los expertos.

El presente estudio analiza la situac ión y los retos didácticos que enfrentan los docentes en el campo del pensamiento matemático especialmente en el nivel medio superior. Durante las últimas décadas, la enseñanza en este campo disciplinar se ha caracterizado por centrarse en la mecanización de los procedimientos con el afán de generar habilidades que automaticen la aplicación de determinadas fórmulas en escenarios diversos, puesto que lo importante es llegar a resultados exactos y válidos desde un punto de vista procedimental. Sin embargo, la falta de comprensión de los conceptos fundamentales, así como la ausencia de reflexión y la falta de conciencia de las acciones realizadas, han generado que el pensamiento matemático continú e siendo una meta difícil de alcanzar en el aprendizaje de las nu evas generaciones. La metodología consistió en un estudio documental con apoyo de las categorías de análisis que conforman la cartografía conceptual, por lo que se realizó un proceso de revisión en fuentes primarias y secundarias del concepto “UVE heurísti ca socioformativa”. Entre los principales resultados destacan las características de la UVE heurística como una estrategia para la gestión del conocimiento, ya que se basa en la comprensión, análisis, interpretación y resolución de un problema del contexto a partir de los saberes que integran una competencia. Esto permite generar actividades de aprendizaje contextualizadas en donde los procedimientos, conceptos y actitudes relacionadas con el pensamiento matemático contribuyan en el mejoramiento de las prácticas docentes, de forma sistemática y fundamentada en nuevos enfoques como la socioformación. Se sugiere considerar los aportes metodológicos obtenidos en esta revisión documental como la base de estudios empíricos que respalden la propuesta socioformativa aplicando la UVE heurística como estrategia de gestión del conocimiento.

Introduction. Prolonged-release tacrolimus (PR-TAC) was associated with improved renal function after transplantation when compared to immediate-release tacrolimus (IR-TAC) although evidence is still scarce. This study aimed to compare clinical outcomes and treatment costs in patients who converted from IR-TAC to PR-TAC during the first year after renal transplantation (RT) (early converters [EC]) or after that period (late converters [LC]). Methods. We performed a retrospective study including 79 patients (EC, 39; LC, 41) which were followed up over 60 months. A mixed-effects approach was used to investigate the differences between both groups regarding renal and metabolic outcomes as well as treatment costs. Results. The median time from RT to conversion was 3 months for EC and 25 months for LC. For both EC and LC, a significant increase in estimated glomerular filtration rate was observed after conversion (5.2 and 4.9 mL/min per 1.73 m 2 , respectively). During the first year after RT, EC presented a higher estimated glomerular filtration rate and inferior tacrolimus trough levels when compared to LC, with higher mean treatment costs associated. However, thereafter, these outcomes were similar between groups over the remaining time. At the end of follow-up, no significant differences were found regarding allograft acute rejection (2.6% and 2.4%), new-onset diabetes (15.7% vs 12.2%) or cardiovascular events (5.2% vs 7.3%). Conclusions. There was a significant benefit on renal function after conversion from IR-TAC to PR-TAC. During the first year after RT, EC presented improved renal function, but higher treatment costs. None of these differences persisted at the end of follow-up. This work was financed by Fundo Europeu de Desenvolvimento Regional (FEDER) funds through the COMPETE 2020—Operacional Programme for Competitiveness and Internationalisation (POCI), Portugal 2020, and by Portuguese funds through FCT—Fundação para a Ciência e a Tecnologia/ Ministério da Ciência, Tecnologia e Ensino Superior in the framework of the project "Institute for Research and Innovation in Health Sciences" (POCI-01-0145-FEDER-007274).

La necesidad de implementar estrategias que favorezcan la gestión del conocimiento con la finalidad de trascender el manejo de la información en una sociedad marcada por el cambio, la resolución de problemas del contexto y la influencia de la tecnología en procesos de innovación científica. Como metodología,se implementóla cartografía conceptual para la organización de la información recabada, lasfuentes primarias y secundarias fueron recuperadas, principalmente,de google académico. Los resultados obtenidos muestran cuatro aspectos claves en la gestión del conocimiento desde la socioformación.A partir de ellos, se tienen las bases de un concepto clave en la transformación de la educación en Latinoamérica que requiere de estudios empíricos para consolidarlo en las futuras reformas pedagógicas.

El propósito del siguiente trabajo es dar a conocer una experiencia educativa con un grupo de estudiantes de nivel bachillerato con el tema de la recuperación de manantiales y aprovechamiento del agua en una comunidad rural del estado de Oaxaca. Se llevó a cabo aplicando un proyecto formativo en el cual se abordó un problema real del contexto que dada su naturaleza fue posible desarrollarla de manera transversal con al apoyo de otras materias. De acuerdo a la necesidad que había dentro de la comunidad para enfrentar tiempos de sequía y aprovechamiento del agua se realizó una campaña de concientización, reforestación, recuperación de yacimientos y mantos acuíferos que se encontraban abandonados con apoyo de estudiantes, padres de familia y autoridades comunales. Trabajar con proyectos formativos desde el enfoque socioformativo es una oportunidad para desarrollar competencias entre los estudiantes dentro y fuera del aula, ya que no se centra en el aprendizaje de los conocimientos, sino que a través de la práctica permite resolver problemáticas reales y contextualizadas, de esta manera el estudiante aprende, reflexiona y participa dentro de la sociedad. Palabras clave : medio ambiente, proyectos formativos, socioformación, sociedad del conocimiento., The purpose of this work is to present an educational experience with a group of high school students with the theme of recovering springs and water use in a rural community in the state of Oaxaca. It was carried out applying a formative project in a real problem of the context was approached, given its nature, it was possible to develop it transversally with the support of other subjects. According to the need within the community to cope with droughts and water use, a campaign was carried out to raise awareness, reforestation, recovery of aquifers and aquifers that were abandoned with the support of students, parents and authorities. Working with training projects from the socioformative approach is an opportunity to develop competences among students inside and outside the classroom, since the practice is not focused on the learning of knowledge, it also allows solving real and contextualized problems, in this way the student learn, reflect and participate in society. Keywords: environment, training projects, socio-formation, knowledge society

The purpose of this work is to present an educational experience with a group of high school students with the theme of recovering springs and water use in a rural community in the state of Oaxaca. It was carried out applying a formative project in a real problem of the context was approached, given its nature, it was possible to develop it transversally with the support of other subjects. According to the need within the community to cope with droughts and water use, a campaign was carried out to raise awareness, reforestation, recovery of aquifers and aquifers that were abandoned with the support of students, parents and authorities. Working with training projects from the socioformative approach is an opportunity to develop competences among students inside and outside the classroom, since the practice is not focused on the learning of knowledge, it also allows solving real and contextualized problems, in this way the student learn, reflect and participate in society., El propósito del siguiente trabajo es dar a conocer una experiencia educativa con un grupo de estudiantes de nivel bachillerato con el tema de la recuperación de manantiales y aprovechamiento del agua en una comunidad rural del estado de Oaxaca. Se llevó a cabo aplicando un proyecto formativo en el cual se abordó un problema real del contexto que dada su naturaleza fue posible desarrollarla de manera transversal con al apoyo de otras materias. De acuerdo a la necesidad que había dentro de la comunidad para enfrentar tiempos de sequía y aprovechamiento del agua se realizó una campaña de concientización, reforestación, recuperación de yacimientos y mantos acuíferos que se encontraban abandonados con apoyo de estudiantes, padres de familia y autoridades comunales. Trabajar con proyectos formativos desde el enfoque socioformativo es una oportunidad para desarrollar competencias entre los estudiantes dentro y fuera del aula, ya que no se centra en el aprendizaje de los conocimientos, sino que a través de la práctica permite resolver problemáticas reales y contextualizadas, de esta manera el estudiante aprende, reflexiona y participa dentro de la sociedad.

El objetivo del presente estudio es determinar la relación entre un conjunto de variables de la evaluación socioformativa y los proyectos formativos en un posgrado en línea. La metodología que se implementó corresponde a un estudio descriptivo-correlacional con una muestra de 79 participantes de una maestría en línea en donde se correlacionó la evaluación socioformativa mediante problemas de contexto, empleo de rúbricas, autoevaluación y coevaluación en el foro académico, con el impacto de los proyectos formativos que hacen énfasis en la importancia de la colaboración y los procesos de mejoramiento de las evidencias considerando los criterios y las metas de desempeño establecidas. Los principales resultados mostraron que la autoevaluación, la coevaluación, los intentos para resolver el problema del contexto, el número de veces que se mejoró la evidencia y los integrantes que conformaron los equipos para la realización de estas presentaron una correlación significativa con el desempeño reflejado en el promedio académico. Por lo tanto, el proceso de retroalimentación continua mediante la autoevaluación y la coevaluación para la mejora de las evidencias realizadas durante el semestre, así como la colaboración y el apoyo para la resolución de problemas del contexto empleando los proyectos formativos, se asocian con un mejor desempeño académico. Se sugiere nuevos estudios para determinar relaciones de causalidad. L'objectiu del present estudi és determinar la relació entre un conjunt de variables de l'avaluació socioformativa i els projectes formatius en un postgrau en línia. La metodologia que es va implementar correspon a un estudi descriptiu correlacional amb una mostra de 79 participants d'un mestratge en línia on es va correlacionar l'avaluació socioformativa mitjançant problemes del context, l'ocupació de rúbriques, l'autoavaluació i la coavaluació en el fòrum acadèmic, amb l'impacte dels projectes formatius que fan èmfasi en la importància de la col·laboració i els processos de millorament de les evidències considerant els criteris i les metes d'acompliment establerts. Els principals resultats van mostrar que l'autoavaluació, la coavaluació, els intents per resoldre el problema del context, el nombre de vegades que es va millorar l'evidència i els integrants que van conformar els equips per a la realització d'aquestes van presentar una correlació significativa amb l'acompliment reflectit en la mitjana acadèmica. Per tant, el procés de retroalimentació contínua mitjançant l'autoavaluació i la coavaluació per a la millora de les evidències realitzades durant el semestre, així com la col·laboració i el suport per a la resolució de problemes del context emprant els projectes formatius s'associen amb un acompliment acadèmic millor. Se suggereixen nous estudis per determinar relacions de causalitat. The objective of this study is to determine the relationship between a set of variables related to socioformative assessment and training projects in the framework of an online postgraduate degree. The methodology comprised a descriptive correlational study with a sample of 79 participants enrolled in an online master's degree. A socioformative assessment model based on context problems, the use of rubrics, and self-assessment and coassessment schemes in an academic forum is correlated with the impact of training projects which emphasize the importance of collaboration and processes to improve the evidence considering the established criteria and performance goals. The main results show that self-assessment, co-assessment, attempts to solve context problems, the number of times that the evidence was improved and the members of teams that were formed to carry out these tasks were significantly correlated with academic performance as reflected in the grade point average. Therefore, ongoing feedback through self-assessment and co-assessment schemes to improve evidence during the academic term, as well as collaboration and support in solving context problems through training projects are associated with better academic performance. Further studies to determine causal relationships are proposed.

Introduction: Fibrinogen Aa chain (AFib) amyloidosis is an autosomal dominant disease that typically presents with predominant renal involvement and has a predictable progressive clinical course [1]. The p.Glu545Val AFib gene (FGA) mutation is at the origin of all AFib amyloidosis cases (AFibE526V [p.Glu545Val]) that have been identified in Portugal so far, and accounts for the disease in 17 families. Current treatment of AFib amyloidosis comprises both supportive measures and disease-modifying approaches, such as liver transplantation [2,3]. Renal transplantation (RTx) is a supportive therapy with risk of premature graft loss due to amyloid recurrence or other unexpected complications related to progression of extrarenal amyloid deposition. The aim of this study was to evaluate the outcome of Portuguese patients with AFibE526V (p.Glu545Val) amyloidosis after RTx. This work was supported by Sociedade Portuguesa de Nefrologia This work was supported by Sociedade Portuguesa de Nefrologia. info:eu-repo/semantics/publishedVersion

El propósito de este artículo fue analizar la naturaleza del trabajo colaborativo en el marco del enfoque socioformativo, con el fin de orientar su aplicación y generar nuevas líneas de investigación. Se realizó un estudio documental apoyado en la estrategia de la cartografía conceptual y de sus ocho ejes. Los principales resultados fueron: 1) el trabajo colaborativo en la socioformación se caracteriza por enfatizar en la resolución de problemas del contexto y la metacognición; 2) difiere del aprendizaje en equipo; 3) se basa en el desarrollo del pensamiento complejo; y 4) se orienta hacia la sociedad del conocimiento. Se recomiendan nuevos estudios para validar los instrumentos de diagnóstico y la metodología propuesta.

Introdução: A ocorrência recente de um conjunto de surtos de dengue em países da lusofonia previamente livres de doença, despertou-nos curiosidade quanto aos fatores concorrentes para o fenómeno e a necessidade de aprofundar conhecimentos quanto à patologia. Revemos a situação relativa à dengue nos países da lusofonia, relacionando os diferentes surtos e procurando contribuir para um melhor conhecimento do fenómeno.Material e Métodos: Revisão da literatura relativa ao tema e informação relevante obtida de comunicações orais.Resultados: Os surtos ocorridos entre os anos de 2009 e 2013 em Cabo Verde, Madeira e Angola (para lá da doença endémica no Brasil) partilham o mesmo vetor Aedes aegypti, mas são devidos a serotipos víricos com diferentes proveniências, como constatado em estudos genotípicos. A forte sub-notificação da doença em África e as dificuldades no diagnóstico e terapêutica são obstáculos ao real conhecimento da situação.Discussão: A hipótese de ligação entre alguns dos surtos não está completamente afastada. Pela elevada mobilidade de pessoas entre estas zonas e pelas alterações climáticas em curso, o território de Portugal expõe-se ao risco de introdução de dengue. A luta principal, a despeito de ferramentas emergentes ainda utópicas, é sem dúvida o controlo vetorial. Conclusão: Não foi possível provar qualquer ligação entre os diferentes surtos, mas é necessária preparação local dos profissionais de saúde, bem como o estabelecimento de estratégias de saúde pública e manutenção de redes de vigilância. Mais estudos epidemiológicos e entomológicos são necessários para caracterizar a verdadeira incidência de doença nos países lusófonos.Palavras-chave: Dengue; Vírus da Dengue; Africa; Brasil; Portugal; Angola; Cabo Verde.

El concepto de liderazgo fue desarrollado principalmente en el ámbito organizacional para estimular a los trabajadores en el logro de las metas establecidas, lo cual a través del tiempo provocó que este término se utilizara en otros ámbitos como el deportivo, gerencial y político. Recientemente en el campo educativo se busca desarrollar el liderazgo de manera pedagógica, distribuida y transformacional en los equipos directivos y docentes de las instituciones para mejorar los resultados de aprendizaje. Con base en la evolución del concepto de liderazgo en los procesos educativos, se realizó un análisis documental con el objetivo de proponer mejoras en la construcción del concepto, teoría y metodología. Se empleó la cartografía conceptual como estrategia para la organización de la información recabada, siguiendo los ocho ejes de análisis de esta metodología, tomado como base fuentes primarias y secundarias recuperadas de google académico y bibliografía complementaria sobre la temática. Los resultados ilustran la importancia de gestionar el talento humano en las instituciones educativas mediante procesos de colaboración, metacognición y fortalecimiento del proyecto ético de vida de quienes participan en la formación de las nuevas generaciones, esto llevará a un liderazgo que trascienda la ejecución de tareas (funciones y roles), y se garantice el desarrollo de personas éticas y autorrealizadas, The concept of leadership was developed mainly in the organizational level to encourage workers in achieving the goals set, which over time caused that this term will be used in other areas such as sports, managerial and political. Recently in the field of education aims to develop leadership in a teaching way, distributed and transformational in the management teams and of the educational institutions to improve learning outcomes. Based on the evolution of the concept of leadership in educational processes, a documentary analysis was conducted with the objective to propose improvements in the construction of the concept, theory and methodology. Employment is the conceptual mapping as a strategy for the organization of the information collected, in accordance with the eight pillars of analysis of this methodology, taken as a base primary and secondary sources retrieved from Google scholar and supplemental bibliography on the topic. The results illustrate the importance of managing the human talent in the educational institutions through collaborative processes, metacognition and strengthening of the ethical project of life of those involved in the formation of the new generations, this will lead to a leadership that transcends the execution of tasks (functions and roles), and ensure the development of self-fulfilling and ethical people

"El presente estudio analiza la situac ión y los retos didácticos que enfrentan los docentes en el campo del pensamiento matemático especialmente en el nivel medio superior. Durante las últimas décadas, la enseñanza en este campo disciplinar se ha caracterizado por centrarse en la mecanización de los procedimientos con el afán de generar habilidades que automaticen la aplicación de determinadas fórmulas en escenarios diversos, puesto que lo importante es llegar a resultados exactos y válidos desde un punto de vista procedimental. Sin embargo, la falta de comprensión de los conceptos fundamentales, así como la ausencia de reflexión y la falta de conciencia de las acciones realizadas, han generado que el pensamiento matemático continú e siendo una meta difícil de alcanzar en el aprendizaje de las nu evas generaciones. La metodología consistió en un estudio documental con apoyo de las categorías de análisis que conforman la cartografía conceptual, por lo que se realizó un proceso de revisión en fuentes primarias y secundarias del concepto “UVE heurísti ca socioformativa”. Entre los principales resultados destacan las características de la UVE heurística como una estrategia para la gestión del conocimiento, ya que se basa en la comprensión, análisis, interpretación y resolución de un problema del contexto a partir de los saberes que integran una competencia. Esto permite generar actividades de aprendizaje contextualizadas en donde los procedimientos, conceptos y actitudes relacionadas con el pensamiento matemático contribuyan en el mejoramiento de las prác ticas docentes, de forma sistemática y fundamentada en nuevos enfoques como la socioformación. Se sugiere considerar los aportes metodológicos obtenidos en esta revisión documental como la base de estudios empíricos que respalden la propuesta socioformativ a aplicando la UVE heurística como estrategia de gestión del conocimiento."