53 results on '"Jonathan Lane"'
Search Results
2. Connecting supplier and DoD blockchains for transparent part tracking
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Francis Asuncion, Adam Brinckman, Dwayne Cole, Jeffrey Curtis, Matt Davis, Timothy Dunlevy, Calvin Farmer, Andrew Harrison, Daniel P. Johnson, Joshua Joyce, Chris Klubertanz, Jonathan Lane, John Martin, Jarek Nabrzyski, Joel Neidig, Deysi Olivares, Gregory Robinson, Gabriel Rodriguez, Chris Root, Karen Rowand, Al Salour, Jeff Score, David Scott, Ian Taylor, Chandler Thompson, Huy Truong, Xiqun Wang, and Dale Warren
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Blockchain ,Smart contracts ,Supply chain ,Department of defense (DoD) ,GraphQL ,Enterprise blockchain systems ,Information technology ,T58.5-58.64 - Abstract
Blockchains have been around for more than ten years, and since 2015, a plethora of systems have been launched to target more flexible use cases. More recently, several enterprise blockchain systems, such as Consensys Quorum and Hyperledger Fabric, have been launched to make blockchain simpler to apply in complex organizational configurations. In this paper, we identify a specific Department of Defense use case, extrapolate requirements, and perform a thorough assessment of the different layers of the blockchain stack to identify the existing state of the art and undertake a gap analysis of the technology for this context. We describe a platform that meets many of these challenges and show how we architected, designed, and implemented a solution for this use case for deployment at NAVAIR. This solution connects transactions from two separate blockchain systems, Consensys Quorum and Hyperledger Fabric, by using a graph-based approach that preserves privacy while enabling full transparency across the military and supplier networks.
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- 2021
- Full Text
- View/download PDF
3. Exposure of Bifidobacterium longum subsp. infantis to Milk Oligosaccharides Increases Adhesion to Epithelial Cells and Induces a Substantial Transcriptional Response.
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Devon W Kavanaugh, John O'Callaghan, Ludovica F Buttó, Helen Slattery, Jonathan Lane, Marguerite Clyne, Marian Kane, Lokesh Joshi, and Rita M Hickey
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Medicine ,Science - Abstract
In this study, we tested the hypothesis that milk oligosaccharides may contribute not only to selective growth of bifidobacteria, but also to their specific adhesive ability. Human milk oligosaccharides (3'sialyllactose and 6'sialyllactose) and a commercial prebiotic (Beneo Orafti P95; oligofructose) were assayed for their ability to promote adhesion of Bifidobacterium longum subsp. infantis ATCC 15697 to HT-29 and Caco-2 human intestinal cells. Treatment with the commercial prebiotic or 3'sialyllactose did not enhance adhesion. However, treatment with 6'sialyllactose resulted in increased adhesion (4.7 fold), while treatment with a mixture of 3'- and 6'-sialyllactose substantially increased adhesion (9.8 fold) to HT-29 intestinal cells. Microarray analyses were subsequently employed to investigate the transcriptional response of B. longum subsp. infantis to the different oligosaccharide treatments. This data correlated strongly with the observed changes in adhesion to HT-29 cells. The combination of 3'- and 6'-sialyllactose resulted in the greatest response at the genetic level (both in diversity and magnitude) followed by 6'sialyllactose, and 3'sialyllactose alone. The microarray data was further validated by means of real-time PCR. The current findings suggest that the increased adherence phenotype of Bifidobacterium longum subsp. infantis resulting from exposure to milk oligosaccharides is multi-faceted, involving transcription factors, chaperone proteins, adhesion-related proteins, and a glycoside hydrolase. This study gives additional insight into the role of milk oligosaccharides within the human intestine and the molecular mechanisms underpinning host-microbe interactions.
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- 2013
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4. The Hapstrument: A Bimanual Haptic Interface for Musical Expression.
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Jonathan Lane-Smith, Derrek Chow, Sahand Ajami, and Jeremy R. Cooperstock
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- 2023
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5. Causal theoretical frameworks that explain veteran mental health help-seeking behavior: a scoping review protocol
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Cameron Charles-Britton, Lydia Woodyatt, Holly Bowen-Salter, Sonia Hines, and Jonathan Lane
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Mental Health Services ,Review Literature as Topic ,Help-Seeking Behavior ,Mental Health ,Quality of Life ,Humans ,General Nursing ,Veterans - Abstract
This scoping review will determine what causal theoretical frameworks have been used to examine veteran mental health help-seeking behavior. The review will also examine the causal factors proposed by these theoretical frameworks, and whether they account for the complex cultural, social, and affective experiences of veterans, which may drive both uptake or avoidance of mental health help-seeking.Some military veterans delay mental health help-seeking, preventing early intervention, creating poor long-term quality of life and functional outcomes, and increasing the likelihood of reaching crisis point before seeking help. There is a distinct lack of research utilizing causal motivational frameworks to explain veteran mental health help-seeking behavior (both engagement and avoidance). To date, no review has been conducted on motivational frameworks used to explain veteran help-seeking behavior. This scoping review will be the first to identify the motivational models that have been used to explain veteran mental health help-seeking, as well as table the proposed causal factors, and determine whether the models account for the cultural, social, and affective experiences of veterans.This scoping review will only consider studies on veteran cohorts. Studies in English that utilize or create an explanatory theory, model, or framework for veteran mental health help-seeking behavior will be included. Literature that focuses solely on intentions rather than behavior will be excluded.Published and unpublished studies and gray literature will be included. Titles and abstracts will be screened, followed by full-text screening. Factors, theories, models, and frameworks used to explain veteran help-seeking behavior will be extracted, charted, and narratively summarized. The JBI methodology for scoping reviews will be used.
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- 2022
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6. Longitudinal changes of human milk oligosaccharides, breastmilk microbiome and infant gut microbiome are associated with maternal characteristics
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Bin Zhang, Shuyuan Yan, Jingyu Yan, Feitong Liu, Zerong Lu, Juchun Chen, Shiting He, and Jonathan Lane
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Immunology ,Microbiome ,Biology ,Industrial and Manufacturing Engineering ,Gut microbiome ,Food Science - Published
- 2021
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7. Multi-level Secure Multicast: The Rethinking of Secure Locks.
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Oskar Scheikl, Jonathan Lane, Robert Boyer, and Mohamed Eltoweissy
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- 2002
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8. Perspective: Leveraging the Gut Microbiota to Predict Personalized Responses to Dietary, Prebiotic, and Probiotic Interventions
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Sean M Gibbons, Thomas Gurry, Johanna W Lampe, Anirikh Chakrabarti, Veerle Dam, Amandine Everard, Almudena Goas, Gabriele Gross, Michiel Kleerebezem, Jonathan Lane, Johanna Maukonen, Ana Lucia Barretto Penna, Bruno Pot, Ana M Valdes, Gemma Walton, Adrienne Weiss, Yoghatama Cindya Zanzer, Naomi V Venlet, Michela Miani, Department of Bio-engineering Sciences, Industrial Microbiology, and UCL - SSS/LDRI - Louvain Drug Research Institute
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Nutrition and Dietetics ,Probiotics ,Medicine (miscellaneous) ,microbiome ,artificial intelligence ,Gastrointestinal Microbiome ,Prebiotics ,probiotics ,Artificial Intelligence ,personalized healthcare ,prebiotic ,WIAS ,microbiota ,Animals ,Humans ,Host-Microbe Interactomics ,precision healthcare ,prebiotics ,diet ,personalized nutrition ,precision nutrition ,probiotic ,Food Science ,VLAG - Abstract
Humans often show variable responses to dietary, prebiotic, and probiotic interventions. Emerging evidence indicates that the gut microbiota is a key determinant for this population heterogeneity. Here, we provide an overview of some of the major computational and experimental tools being applied to critical questions of microbiota-mediated personalized nutrition and health. First, we discuss the latest advances in in silico modeling of the microbiota-nutrition-health axis, including the application of statistical, mechanistic, and hybrid artificial intelligence models. Second, we address high-throughput in vitro techniques for assessing interindividual heterogeneity, from ex vivo batch culturing of stool and continuous culturing in anaerobic bioreactors, to more sophisticated organ-on-a-chip models that integrate both host and microbial compartments. Third, we explore in vivo approaches for better understanding of personalized, microbiota-mediated responses to diet, prebiotics, and probiotics, from nonhuman animal models and human observational studies, to human feeding trials and crossover interventions. We highlight examples of existing, consumer-facing precision nutrition platforms that are currently leveraging the gut microbiota. Furthermore, we discuss how the integration of a broader set of the tools and techniques described in this piece can generate the data necessary to support a greater diversity of precision nutrition strategies. Finally, we present a vision of a precision nutrition and healthcare future, which leverages the gut microbiota to design effective, individual-specific interventions.
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- 2022
9. Connecting supplier and DoD blockchains for transparent part tracking
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Gregory Robinson, Chris Root, Francis Asuncion, Al Salour, Jarek Nabrzyski, Jeff Score, Timothy Dunlevy, Dale Warren, Chandler Thompson, Andrew Harrison, Daniel P. Johnson, Calvin Farmer, Chris Klubertanz, Deysi Olivares, David F. Scott, Karen Rowand, John Martin, Ian Taylor, Dwayne Cole, Huy Truong, Gabriel Rodriguez, Xiqun Wang, Adam Brinckman, Jeffrey L. Curtis, Jonathan Lane, Matthew Davis, Joel Neidig, and Joshua Joyce
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GraphQL ,Blockchain ,Computer science ,General Engineering ,Context (language use) ,Transparency (human–computer interaction) ,Information technology ,Gap analysis ,Supply chain ,T58.5-58.64 ,Enterprise blockchain systems ,Software deployment ,Systems engineering ,General Earth and Planetary Sciences ,Graph (abstract data type) ,Use case ,State (computer science) ,Smart contracts ,Department of defense (DoD) ,General Environmental Science - Abstract
Blockchains have been around for more than ten years, and since 2015, a plethora of systems have been launched to target more flexible use cases. More recently, several enterprise blockchain systems, such as Consensys Quorum and Hyperledger Fabric, have been launched to make blockchain simpler to apply in complex organizational configurations. In this paper, we identify a specific Department of Defense use case, extrapolate requirements, and perform a thorough assessment of the different layers of the blockchain stack to identify the existing state of the art and undertake a gap analysis of the technology for this context. We describe a platform that meets many of these challenges and show how we architected, designed, and implemented a solution for this use case for deployment at NAVAIR. This solution connects transactions from two separate blockchain systems, Consensys Quorum and Hyperledger Fabric, by using a graph-based approach that preserves privacy while enabling full transparency across the military and supplier networks.
- Published
- 2021
10. Australian military and veteran’s mental health care part 1: an introduction to cultural essentials for clinicians
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Duncan Wallace and Jonathan Lane
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Mental Health Services ,Health Knowledge, Attitudes, Practice ,050103 clinical psychology ,05 social sciences ,Australia ,Military culture ,03 medical and health sciences ,Psychiatry and Mental health ,Military Personnel ,0302 clinical medicine ,Nursing ,Humans ,Mental health care ,0501 psychology and cognitive sciences ,030212 general & internal medicine ,Cultural Competency ,Psychology ,Cultural competence ,Veterans - Abstract
Objective: This article aims to define the cultural specificity of Australian military and veterans, and introduce some of the essential clinician knowledge, skills and attitudes required for effective cultural competence in the management of mental health (MH) conditions in this population. Conclusion: Military culture has the defining characteristics of the military as an organisation with a formal structure, as a cultural group governed by norms and shared values, and as a social group that provides people with identities. Key requirements for cultural competence introduced here are basic knowledge of the military structure, norms and identity; clinical skills including basic assessment and awareness of the commonly occurring MH disorders; and an exploration of attitudes of both the clinician and the military or veteran patient. Further research is needed, particularly in terms of assessing clinician’s cultural competence.
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- 2020
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11. Assessment of HDR brachytherapy-replicating prostate radiotherapy planning for tomotherapy, cyberknife and VMAT
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Elizabeth Brown, Paul H. Charles, David Waterhouse, Alan Glyde, Ben Hug, Kate Howe, Alice Grigg, Cathy Hargrave, Romena de Chavez, Garry Grogan, David Pryor, James Hellyer, Martin A. Ebert, Sean Bydder, and Jonathan Lane
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Male ,Organs at Risk ,Radiological and Ultrasound Technology ,business.industry ,medicine.medical_treatment ,Radiotherapy Planning, Computer-Assisted ,Brachytherapy ,Prostate ,Radiotherapy Dosage ,Radiosurgery ,Tomotherapy ,Multileaf collimator ,Oncology ,Cyberknife ,Medicine ,Dosimetry ,Humans ,Radiology, Nuclear Medicine and imaging ,External beam radiotherapy ,Radiotherapy, Intensity-Modulated ,business ,Nuclear medicine ,Radiation treatment planning ,Radiation oncologist - Abstract
A dosimetric study was undertaken to assess the ability of Cyberknife (CK), Volumetric Modulated Arc Therapy (VMAT), and TomoTherapy (Tomo) to generate treatment plans that mimic the dosimetry of high dose-rate brachytherapy (HDR BT) for prostate cancer. The project aimed to assess the potential of using stereotactic body radiotherapy (SBRT) for boost treatment of high-risk prostate cancer patients where HDR BT in combination with conformal external beam radiotherapy (EBRT) is the standard of care. The datasets of 6 prostate patients previously treated with HDR BT were collated. VMAT, CK, and TomoTherapy treatment plans were generated for each dataset using the target and organ-at-risk structures as defined by the Radiation Oncologist during the HDR BT treatment process. The HDR BT plan isodoses were also converted into planning structures to assist the other modalities to achieve a HDR BT-like dose distribution. CK plans were created using both the iris collimator (IC) and a multileaf collimator (MLC). Comparison of the techniques was made based on dose-volume indices. Each plan was created at centres experienced using the respective treatment planning systems (TPS). Planning target volume (PTV V100%), i.e., the volume of the planning target volume (PTV) receiving 100% of the relative dose, in VMAT and TomoTherapy SBRT plans was higher than HDR BT plans. PTV V150% and V200%, i.e., volume of the PTV receiving 150% and 200% of the relative dose, were approached on all the CK MLC and TomoTherapy SBRT plans. However, it is not presently achievable for "virtual brachytherapy" SBRT to replicate the same high intraprostatic doses as HDR BT while meeting the constraints on the organs-at-risk (OARs). Half of the CK IC plans achieved PTV V150% but this was at the expense of high rectal dose. TomoTherapy and CK MLC plans achieved PTV V150% and V200% but the bladder dose was higher compared to CK IC plans. VMAT exhibited excellent PTV coverage based on V100 and OAR sparing, but without any ability to achieve the high intra-prostatic doses of HDR (V150% and V200%). SBRT techniques can be used to deliver hypofractionated radiotherapy to the PTV V100%. Based on the comparison of "physical" dose distributions, SBRT cannot presently achieve the same high intraprostatic doses as HDR BT while respecting the OAR constraints. SBRT still remains an attractive treatment option for delivering hypofractionated treatments for prostate cancer compared to HDR BT, in particular as it is less invasive and less resource intensive. Long-term outcomes of clinical trials comparing HDR BT and SBRT "prostate boosts" may show whether the high intraprostatic doses are clinically significant and correlate with outcomes.
- Published
- 2021
12. Culturally Informed Interventions for Military, Veteran and Emergency Service Personnel: The Importance of Group Structure, Lived Experience Facilitators, and Recovery-Oriented Content
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Jonathan Lane, Miranda Van Hooff, Ellie Lawrence-Wood, and Alexander McFarlane
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education - Abstract
There is little available research on what constitutes a culturally informed program to treat mental health conditions among military, veteran, and emergency services personnel. The current study presents the qualitative participant evaluations of a modified group Skills Training in Affective and Interpersonal Regulation (STAIR) program. Participants were grouped with either lived-experience facilitators or non-lived-experience clinicians for the program, and 93 textual responses to a series of qualitative questions were analyzed. The findings suggest strong support for the postulated three primary components of a culturally informed program: a group structure; facilitation by peers with lived experience; and functional, skills-based, and recovery-oriented content.
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- 2021
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13. CyberKnife® fixed cone and Iris™ defined small radiation fields: Assessment with a high‐resolution solid‐state detector array
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Ebert A. Martin, Jonathan Lane, Susanna Guatelli, Vladimir Perevertaylo, Marco Petasecca, Tomas Kron, Giordano Biasi, Benjamin Hug, Anatoly B. Rosenfeld, and Garry Grogan
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87.55.Qr ,CyberKnife ,87.56.Fc ,SRT ,quality assurance ,Radiosurgery ,Linear particle accelerator ,030218 nuclear medicine & medical imaging ,law.invention ,03 medical and health sciences ,0302 clinical medicine ,Optics ,Cyberknife ,law ,Dosimetry ,Radiation Oncology Physics ,Radiology, Nuclear Medicine and imaging ,Radiometry ,Instrumentation ,Image resolution ,small‐field dosimetry ,Physics ,Radiation ,Dosimeter ,business.industry ,Detector ,87.55.k ,Reproducibility of Results ,Collimator ,87.57.uq ,Multileaf collimator ,030220 oncology & carcinogenesis ,Particle Accelerators ,business ,87.53.Ly ,87.53.Bn ,2D monolithic silicon array detector ,Monte Carlo Method - Abstract
Purpose The challenges of accurate dosimetry for stereotactic radiotherapy (SRT) with small unflattened radiation fields have been widely reported in the literature. In this case, suitable dosimeters would have to offer a submillimeter spatial resolution. The CyberKnife® (Accuray Inc., Sunnyvale, CA, USA) is an SRT‐dedicated linear accelerator (linac), which can deliver treatments with submillimeter positional accuracy using circular fields. Beams are delivered with the desired field size using fixed cones, the InCise™ multileaf collimator or a dynamic variable‐aperture Iris™ collimator. The latter, allowing for field sizes to be varied during treatment delivery, has the potential to decrease treatment time, but its reproducibility in terms of output factors (OFs) and dose profiles (DPs) needs to be verified. Methods A 2D monolithic silicon array detector, the “Octa”, was evaluated for dosimetric quality assurance (QA) for a CyberKnife system. OFs, DPs, percentage depth‐dose (PDD) and tissue maximum ratio (TMR) were investigated, and results were benchmarked against the PTW SRS diode. Cross‐plane, in‐plane and 2 diagonal dose profiles were measured simultaneously with high spatial resolution (0.3 mm). Monte Carlo (MC) simulations with a GEANT4 (GEometry ANd Tracking 4) tool‐kit were added to the study to support the experimental characterization of the detector response. Results For fixed cones and the Iris, for all field sizes investigated in the range between 5 and 60 mm diameter, OFs, PDDs, TMRs, and DPs in terms of FWHM measured by the Octa were accurate within 3% when benchmarked against the SRS diode and MC calculations. Conclusions The Octa was shown to be an accurate dosimeter for measurements with a 6 MV FFF beam delivered with a CyberKnife system. The detector enabled real‐time dosimetric verification for the variable aperture Iris collimator, yielding OFs and DPs consistent with those obtained with alternative methods.
- Published
- 2018
14. Contradictory concepts in tortuosity determination in porous media in electrochemical devices
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Paul R. Shearing, Bernhard Tjaden, Dan J. L. Brett, Donal P. Finegan, and Jonathan Lane
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Materials science ,Field (physics) ,Applied Mathematics ,General Chemical Engineering ,Analytical chemistry ,Flux ,02 engineering and technology ,General Chemistry ,Mechanics ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Tortuosity ,Industrial and Manufacturing Engineering ,0104 chemical sciences ,Electrode ,Gaseous diffusion ,Knudsen number ,0210 nano-technology ,Porous medium ,Porosity - Abstract
Porous media are a vital component in almost every electrochemical device in the form of electrode, support or gas diffusion layers. Microstructural parameters of porous layers such as tortuosity, porosity and pore size diameter are of high importance and crucial for diffusive mass transport calculations. Among these parameters, the tortuosity remains ill-defined in the field of electrochemistry, resulting in a wide range of different calculation approaches. Here, we present a systematic approach of calculating the tortuosity of different porous samples using image and diffusion cell experimental-based methods. Image-based analyses include a selection of geometric and flux-based tortuosity calculation algorithms. Differences between the image and diffusion cell-based results are encountered and attributed to the small pore diameters and thereby induced Knudsen effects within the samples which govern the diffusion flux.
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- 2017
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15. Survival rates of teeth treated with bacterial photo-dynamic therapy during disinfection of the root canal system
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Jonathan Lane and Stephen J Bonsor
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Dental practice ,Dental Pulp Cavity ,business.industry ,Photo dynamic therapy ,Root canal ,Dentistry ,Retrospective cohort study ,030206 dentistry ,law.invention ,Root Canal Therapy ,Disinfection ,Survival Rate ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Randomized controlled trial ,law ,medicine ,030212 general & internal medicine ,business ,General Dentistry ,Survival rate ,Survival analysis ,Retrospective Studies - Abstract
Objective To ascertain the survival of teeth having undergone root canal therapy, when bacterial photo-dynamic therapy (bacterial PDT) was used as an adjunct during root canal system disinfection. Design Retrospective survival analysis (Kaplan-Meier method) of endodontically-treated teeth, when bacterial PDT was used as an adjunct during root canal system disinfection by a single operator in a private general dental practice. Materials and methods The records relating to endodontically treated teeth, performed between 27 May 2001 and 23 June 2016, were sourced. The details of these were placed into a database that permitted flexible interrogation. Survival data on de novo root canal treated teeth (RCT), and those requiring revision of the endodontic treatment (reRCT), were exported into a statistical package to permit survival analysis by the method of Kaplan-Meier. Results The number of teeth available for analysis were RCT = 620 and reRCT = 167. Percentage survival at two, four, six, eight, and ten years for RCT was 98.31, 97.38, 95.76, 91.81 and 91.80 respectively. When non-endodontic failures were excluded percentage survival was 99.27, 98.91, 98.28, 97.33 and 97.33 respectively. Percentage survival of teeth having undergone reRCT at the same time periods was 94.14, 92.77, 86.52, 84.09 and 84.09 respectively and respectively. When non-endodontic failures were excluded percentage survival was 96.01,96.01,93.67,63.67 and 93.67 respectively. Conclusions Within the limitations of the study, the survival rates of teeth treated with bacterial PDT, as an adjunct during root canal system disinfection, compare very favourably with previously published work where bacterial PDT was not used. The effectiveness of conventional chemo-mechanical disinfection of the root canal system may be enhanced by the adjunctive use of bacterial PDT, particularly in reRCT cases.
- Published
- 2019
16. Comparison of Ionic and Diffusive Mass Transport Resistance in Porous Structures
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Chun Tan, Jonathan Lane, Leon D. Brown, Dan J. L. Brett, Bernhard Tjaden, Mailis M. Lounasvuori, Thomas Mason, Tobias P. Neville, and Paul R. Shearing
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Mass transport ,Range (particle radiation) ,Knudsen diffusion ,business.industry ,Chemical physics ,Chemistry ,Electrical engineering ,Gaseous diffusion ,Ionic bonding ,Porosity ,Microstructure ,business ,Tortuosity - Abstract
The tortuosity of a porous structure is commonly used to relate the bulk transport property to an effective transport property. This approach is applied for a wide range of phenomena including charge transport and gas diffusion alike. However, due to the inherent differences between ionic and diffusive transport, the effect of the microstructure on either effective transport property differs. Here, we calculate the tortuosity of a porous membrane via gas diffusion experiments and ionic resistance measurements and compare the results of both techniques. The ionic resistance measurement arrives at lower tortuosity value compared to the gas diffusion measurements. The reason for this might stem from Knudsen diffusion effects, which only affect diffusive mass transport in the gas phase and is affected by the local variation in pore diameter. Hence, Knudsen diffusion effects cannot be neglected in microstructures featuring nano-scale pores.
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- 2017
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17. The application of 3D imaging techniques, simulation and diffusion experiments to explore transport properties in porous oxygen transport membrane support materials
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Paul R. Shearing, Robert S. Bradley, Jonathan Lane, Philip J. Withers, Bernhard Tjaden, and Dan J. L. Brett
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Chemistry ,020209 energy ,Flow (psychology) ,Oxygen transport ,Analytical chemistry ,02 engineering and technology ,General Chemistry ,Mechanics ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,Tortuosity ,Knudsen diffusion ,Phase (matter) ,0202 electrical engineering, electronic engineering, information engineering ,General Materials Science ,Tomography ,Diffusion (business) ,0210 nano-technology ,Porosity - Abstract
Tortuosity plays a vital role in diffusive mass transport through porous layers of electrochemical devices. However, tortuosity cannot be measured directly which is why different methods have been developed to determine the tortuosity of porous samples. These methods differ considerably from each other in terms of calculation approach and applied data sets. Here, we utilise advanced tomography techniques, simulation and diffusion cell experiments to calculate tortuosity of a porous support layer of an oxygen transport membrane (OTM). The results are then compared and the suitability of these different approaches is evaluated. We conclude, that image and simulation based methodologies arrive at lower tortuosity values in comparison to diffusion cell experiments; the difference, depending on the calculation method, can be close to a factor of two. The difference may stem from Knudsen diffusion effects which currently are not accounted for in the image based modelling techniques. Moreover, tortuosity values extracted via diffusion cell experiments are a function of gas mixture and temperature. As a result, one has to distinguish between geometric tortuosity and diffusive tortuosity used for quantifying the resistance of a structure to a flux.
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- 2016
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18. Interfacial stability of iron doped lanthanum strontium chromite and Scandia stabilized zirconia in oxidizing and reducing atmosphere
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Pawel Plonczak, Jonathan Lane, Jamie R. Wilson, Sapna Gupta, and Prabhakar Singh
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Strontium ,Materials science ,Chemistry(all) ,Reducing atmosphere ,Inorganic chemistry ,Oxygen transport ,chemistry.chemical_element ,02 engineering and technology ,General Chemistry ,Partial pressure ,010402 general chemistry ,021001 nanoscience & nanotechnology ,Condensed Matter Physics ,01 natural sciences ,Zirconate ,0104 chemical sciences ,Materials Science(all) ,chemistry ,Oxidizing agent ,Lanthanum ,General Materials Science ,Cubic zirconia ,0210 nano-technology - Abstract
This study reports the interfacial stability of doped (La 0.8 Sr 0.2 ) 0.95 Cr 0.7 Fe 0.3 O 3 (LSCF) and 10Sc1CeSZ system in oxidizing and reducing atmosphere for the application of oxygen transport membrane (OTM) device. Role of oxygen partial pressure (PO 2 ) on the interfacial stability of LSCF with 10Sc1CeSZ is studied under OTM fabrication conditions (1400 °C, PO 2 ~ 0.21–10 − 10 atm). Interfacial stability corresponding to the interaction between LSCF and 10Sc1CeSZ decreases with decrease in PO 2 . Interfacial study of LSCF with 10Sc1CeSZ shows absence and presence of strontium zirconate (SrZrO 3 ) at the interface in oxidizing (PO 2 ~ 0.21 atm) and reducing atmosphere (PO 2 ~ 10 − 10 atm) at 1400 °C respectively. Mechanism for the formation of SrZrO 3 is reported.
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- 2016
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19. Xiang Study: an association of breastmilk composition with maternal body mass index and infant growth during the first 3 month of life
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Patrice Malard, Jie Li, Jonathan Lane, Feitong Liu, Xuyi Peng, Shuyuan Yan, and Juchun Chen
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0301 basic medicine ,medicine.medical_specialty ,growth ,body mass index ,030209 endocrinology & metabolism ,fatty acids ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,Lactation ,medicine ,Humans ,Mass index ,Prospective cohort study ,Original Research ,chemistry.chemical_classification ,milk ,030109 nutrition & dietetics ,Nutrition and Dietetics ,business.industry ,Fatty acid ,Endocrinology ,medicine.anatomical_structure ,breast feeding ,chemistry ,Cohort ,lipids (amino acids, peptides, and proteins) ,business ,Body mass index ,Breast feeding ,Food Science ,Polyunsaturated fatty acid - Abstract
BACKGROUND/OBJECTIVES This study aimed to establish a mother and child cohort in the Chinese population, and investigate human breastmilk (HBM) composition and its relationship with maternal body mass index (BMI) and infant growth during the first 3 mon of life. SUBJECTS/METHODS A total of 101 Chinese mother and infant pairs were included in this prospective cohort. Alterations in the milk macronutrients of Chinese mothers at 1 mon (T1), 2 mon (T2), and 3 mon (T3) lactation were analyzed. HBM fatty acid (FA) profiles were measured by gas chromatography (GC), and HBM proteomic profiling was achieved by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry (MS). RESULTS During the first 3 mon of lactation (P < 0.05), significant decreases were determined in the levels of total energy, fat, protein, and osteopontin (OPN), as well as ratios of long-chain saturated FA (including C16:0, C22:0 and C24:0), monounsaturated FA (including C16:1), and n-6 poly unsaturated FA (PUFA) (including C20:3n-6 and C20:4n-6, and n-6/n-3). Conversely, butyrate, C6:0 and n-3 PUFA C18:3n-3 (α-linolenic acid, ALA) were significantly increased during the first 3 mon (P < 0.05). HBM proteomic analyses distinguished compositional protein differences over time (P = 0.001). Personalized mother-infant analyses demonstrated that HBM from high BMI mothers presented increased total energy, fat, protein and OPN, and increased content of n-6 PUFA (including C18:3n-6, C20:3n-6 and n-6/n-3 ratio) as compared with low BMI mothers (P < 0.05). Furthermore, BMI of the mothers positively correlated with the head circumference (HC) of infants as well as the specific n-6 PUFA C20:3n-6 over the 3 time points examined. Infant HC was negatively associated with C18:0. CONCLUSION This study provides additional evidence to the Chinese HBM database, and further knowledge of FA function. It also helps to establish future maternal strategies that support the healthy growth and development of Chinese infants.
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- 2021
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20. Quality assurance of Cyberknife robotic stereotactic radiosurgery using an angularly independent silicon detector
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Marco Petasecca, S. Alhujaili, Garry Grogan, S. Alshaikh, Belal Moftah, Jonathan Lane, Martin A. Ebert, Giordano Biasi, F. Alzorkany, Muhammed A. Al Kafi, Pejman Rowshan Farzad, Benjamin Hug, Anatoly B. Rosenfeld, and A. H. Aldosari
- Subjects
Organs at Risk ,87.55.Qr Quality assurance in radiotherapy ,Materials science ,Quality Assurance, Health Care ,Exposure Assessment ,medicine.medical_treatment ,87.53.Ly Stereotactic radiosurgery ,stereotactic radiosurgery ,Dose profile ,Radiosurgery ,small field dosimetry ,Imaging phantom ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Optics ,Robotic Surgical Procedures ,Cyberknife ,Neoplasms ,cyberknife ,medicine ,Dosimetry ,Humans ,Radiation Oncology Physics ,Radiology, Nuclear Medicine and imaging ,Radiometry ,Instrumentation ,silicon detector ,Diode ,Radiation ,business.industry ,Phantoms, Imaging ,Radiotherapy Planning, Computer-Assisted ,Radiotherapy Dosage ,angular dependence ,Full width at half maximum ,030220 oncology & carcinogenesis ,Ionization chamber ,Radiotherapy, Intensity-Modulated ,business - Abstract
Purpose The aim of this work was to evaluate the use of an angularly independent silicon detector (edgeless diodes) developed for dosimetry in megavoltage radiotherapy for Cyberknife in a phantom and for patient quality assurance (QA). Method The characterization of the edgeless diodes has been performed on Cyberknife with fixed and IRIS collimators. The edgeless diode probes were tested in terms of basic QA parameters such as measurements of tissue‐phantom ratio (TPR), output factor and off‐axis ratio. The measurements were performed in both water and water‐equivalent phantoms. In addition, three patient‐specific plans have been delivered to a lung phantom with and without motion and dose measurements have been performed to verify the ability of the diodes to work as patient‐specific QA devices. The data obtained by the edgeless diodes have been compared to PTW 60016, SN edge, PinPoint ionization chamber, Gafchromic EBT3 film, and treatment planning system (TPS). Results The TPR measurement performed by the edgeless diodes show agreement within 2.2% with data obtained with PTW 60016 diode for all the field sizes. Output factor agrees within 2.6% with that measured by SN EDGE diodes corrected for their field size dependence. The beam profiles’ measurements of edgeless diodes match SN EDGE diodes with a measured full width half maximum (FWHM) within 2.3% and penumbra widths within 0.148 mm. Patient‐specific QA measurements demonstrate an agreement within 4.72% in comparison with TPS. Conclusion The edgeless diodes have been proved to be an excellent candidate for machine and patient QA for Cyberknife reproducing commercial dosimetry device measurements without need of angular dependence corrections. However, further investigation is required to evaluate the effect of their dose rate dependence on complex brain cancer dose verification.
- Published
- 2018
21. A novel class of gas separation membrane based on organic ionic plastic crystals
- Author
-
Jennifer M. Pringle, Maria Forsyth, Jonathan Lane Mcdonald, and Douglas R. MacFarlane
- Subjects
Materials science ,Nanofiber composites ,Metals and Alloys ,Ionic bonding ,02 engineering and technology ,General Chemistry ,010402 general chemistry ,021001 nanoscience & nanotechnology ,01 natural sciences ,Catalysis ,0104 chemical sciences ,Surfaces, Coatings and Films ,Electronic, Optical and Magnetic Materials ,Membrane ,Chemical engineering ,Permeability (electromagnetism) ,Thermal ,Materials Chemistry ,Ceramics and Composites ,Organic chemistry ,Gas separation ,Plastic crystal ,0210 nano-technology - Abstract
The first use of organic ionic plastic crystals (OIPCs) as CO2 separation membranes is reported. The novel OIPC/PVDF nanofiber composites show CO2/N2 ideal selectivities of 30 at 35 °C. The dependence of gas permeability on the thermal phase of the plastic crystals is discussed.
- Published
- 2016
- Full Text
- View/download PDF
22. EP-1725: Quality assurance of Robotic SRS (Cyberknife) by an innovative angular independent silicon detector
- Author
-
Belal Moftah, Anatoly B. Rosenfeld, M. Petasecca, S. Alshaikh, Benjamin Hug, A. H. Aldosari, Giordano Biasi, Jonathan Lane, M.A. Al Kafi, F. Alzorkany, Martin A. Ebert, P.R. Farzad, Garry Grogan, and S. Alhujaili
- Subjects
Oncology ,Cyberknife ,business.industry ,Computer science ,Silicon detector ,Radiology, Nuclear Medicine and imaging ,Hematology ,business ,Quality assurance ,Simulation - Published
- 2018
- Full Text
- View/download PDF
23. Racecar Front Wing Aerodynamics
- Author
-
Jonathan Lane and Wael A. Mokhtar
- Subjects
Wing ,business.industry ,Computer science ,General Medicine ,Aerodynamics ,Aerospace engineering ,business ,Front (military) - Published
- 2008
- Full Text
- View/download PDF
24. Recovery. Oxygen Transport Membrane-Based OxyCombustion for CO2 Capture from Power Plants
- Author
-
Pawel Plonczak, Sean M. Kelly, Jiefeng Lin, John Peck, Jonathan Lane, Yunxiang Lu, Jamie R. Wilson, Mahesh Biradar, Javier E. Gonzalez, Chuck Robinson, Max Christie, Ines C. Stuckert, Zigui Lu, Juan Li, Sadashiv M. Swami, Joan Geary, and Shrikar Chakravrti
- Subjects
Membrane ,Waste management ,Natural gas ,business.industry ,Oxygen transport ,Environmental science ,business ,Power (physics) - Published
- 2015
- Full Text
- View/download PDF
25. Early barriers for University rural clinical placements
- Author
-
Joseph V. Turner and Jonathan Lane
- Subjects
Medical education ,Students, Medical ,Education, Medical ,Multi disciplinary ,Higher education ,business.industry ,Rural health ,Allied Health Personnel ,General Medicine ,Education ,Nursing ,Health Care Surveys ,Workforce ,Humans ,Medicine ,Queensland ,Rural Health Services ,business ,Clinical learning - Published
- 2006
- Full Text
- View/download PDF
26. Mitigation of the deleterious effect of silicon species on the conductivity of ceria electrolytes
- Author
-
G.M. Christie, Jonathan Lane, and J.L. Neff
- Subjects
Alkaline earth metal ,Materials science ,Silicon ,Doping ,Inorganic chemistry ,technology, industry, and agriculture ,chemistry.chemical_element ,General Chemistry ,Electrolyte ,Conductivity ,Condensed Matter Physics ,chemistry ,Electrical resistivity and conductivity ,General Materials Science ,Grain boundary - Abstract
The deleterious effect of silicon species on the conductivity of ceria electrolytes is well documented in the literature. A simple process has been developed at Praxair that alleviates the negative effect of high concentrations of silicon species on the conductivity of ceria electrolytes. The impact of this process on the conductivity of commercially available doped ceria electrolyte powders is demonstrated and a likely mechanism for the reduction of the resistivity is proposed. The influence of this process on other properties of the ceria electrolyte is discussed.
- Published
- 2006
- Full Text
- View/download PDF
27. Understanding transport phenomena in electrochemical energy devices via X-ray nano CT
- Author
-
Paul R. Shearing, Jonathan Lane, Dan J. L. Brett, and Bernhard Tjaden
- Subjects
History ,Materials science ,Oxide ,Oxygen transport ,Nanotechnology ,Microstructure ,Electrochemical energy conversion ,Tortuosity ,Computer Science Applications ,Education ,chemistry.chemical_compound ,chemistry ,Chemical engineering ,Nano ,Transport phenomena ,Porosity - Abstract
Porous support layers in electrochemical devices ensure mechanical stability of membrane assemblies such as solid oxide fuel cells and oxygen transport membranes (OTMs). At the same time, porous layers affect diffusive mass transport of gaseous reactants and contribute to performance losses at high fuel utilisation and conversion ratios. Microstructural characteristics are vital to calculate mass transport phenomena, where tortuosity remains notoriously difficult to determine. Here, the tortuosity of tubular porous support layers of OTMs is evaluated via high resolution X-ray nano computed tomography. The high resolution reveals the complex microstructure of the samples to then execute a selection of image-based tortuosity calculation algorithms. Visible differences between geometric and flux-based algorithms are observed and have thus to be applied with caution.
- Published
- 2017
- Full Text
- View/download PDF
28. Robust Design of Reliability Test Plans Using Degradation Measures
- Author
-
Jonathan Lane and Stephen Crowder
- Subjects
Engineering ,Measure (data warehouse) ,business.industry ,Ongoing reliability test ,Production (economics) ,Test plan ,Duration (project management) ,business ,Reliability (statistics) ,Degradation (telecommunications) ,Reliability engineering ,Test (assessment) - Abstract
With short production development times, there is an increased need to demonstrate product reliability relatively quickly with minimal testing. In such cases there may be few if any observed failures. Thus, it may be difficult to assess reliability using the traditional reliability test plans that measure only time (or cycles) to failure. For many components, degradation measures will contain important information about performance and reliability. These measures can be used to design a minimal test plan, in terms of number of units placed on test and duration of the test, necessary to demonstrate a reliability goal. Generally, the assumption is made that the error associated with a degradation measure follows a known distribution, usually normal, although in practice cases may arise where that assumption is not valid. In this paper, we examine such degradation measures, both simulated and real, and present non-parametric methods to demonstrate reliability and to develop reliability test plans for the future production of components with this form of degradation.
- Published
- 2014
- Full Text
- View/download PDF
29. Being Santa Claus : What I Learned About the True Meaning of Christmas
- Author
-
Sal Lizard, Jonathan Lane, Sal Lizard, and Jonathan Lane
- Subjects
- Santa Claus
- Abstract
A veteran Santa reveals heartwarming true stories and lessons from his twenty-year career spreading Christmas magic.With the holiday shopping season beginning earlier each year, more than ever. Americans are struggling to remember the true meaning of Christmas. And who better to deliver the gift of Christmas inspiration than a man who has spent the last two decades playing Santa?Sal Lizard was in his twenties when his beard and hair turned completely white. Today he appears everywhere from malls and parades to schools and hospitals. And— from his custom-made red velvet suits to the mistletoe that hangs from the rearview mirror in his Santa-mobile—he is Santa Claus three hundred and sixty-five days a year. In Being Santa Claus Sal reflects on his experiences with both children and adults including: Christmas magic is all around us: We don't always see it, but it is there, shaping and enriching our lives. Sometimes you need to go that extra mile:Santa Claus is the one person who can't even use a blizzard as an excuse not to honor his commitments, and Sal teaches adults the importance of always showing up for our children. Even a small child can make a big difference: Sal has met some impressive children over the years, and he's learned that you don't need to be a grown-up to make an impact on the world around you.In Being Santa Claus Sal shares these lessons, along with often heartwarming, occasionally heartbreaking, and sometimes downright hysterical stories from his twenty-year career as Santa.
- Published
- 2012
30. Foundation Website Creation with HTML5, CSS3, and JavaScript
- Author
-
Joe Lewis, Jonathan Lane, Meitar Moscovitz, Tom Barker, Joe Lewis, Jonathan Lane, Meitar Moscovitz, and Tom Barker
- Subjects
- HTML (Document markup language), Web site development, Web sites--Design, JavaScript (Computer program language), Cascading style sheets
- Abstract
Foundation Website Creation with HTML5, CSS3, and JavaScript shows the entire process of building a website. This process involves much more than just technical knowledge, and this book provides all the information you'll need to understand the concepts behind designing and developing for the Web, as well as the best means to deliver professional results based on best practices. Of course, there is far more to building a successful website than knowing a little Hypertext Markup Language (HTML). The process starts long before any coding takes place, and this book introduces you to the agile development process, explaining why this method makes so much sense for web projects and how best to implement it. We also make sure you're up to date by using the latest HTML5 features. Planning is vital, so you'll also learn to use techniques such as brainstorming, wireframes, mockups, and prototypes to get your project off to the best possible start and help ensure smooth progress as it develops. An understanding of correct, semantic markup is essential for any web professional; this book explains how HTML5 should be used to structure content so that the markup adheres to current web standards. You'll learn about the wide range of HTML5 elements available to you, and you'll learn how and when to use them through building example web pages. Without creative use of Cascading Style Sheets (CSS), websites would all look largely the same. CSS enables you to set your website apart from the rest, while maintaining the integrity of your markup. We'll showcase the new features of CSS3 and how you can use them. You'll learn how CSS3 works and how to apply styles to your pages, allowing you to realize your design ideas in the browser. JavaScript can be used to make your website easier and more interesting to use. This book provides information on appropriate uses of this technology and introduces the concepts of JavaScriptprogramming. You'll also see how JavaScript works as part of the much-hyped technique Ajax, and in turn, where Ajax fits into the wider Web 2.0 picture. While a website is being built, it needs to be tested across multiple browsers and platforms to ensure that the site works for all users, regardless of ability or disability, and this book explains how best to accomplish these tasks. Then, it discusses the process of launching and maintaining the site so that it will continue to work for all its users throughout its life cycle. Foundation Website Creation with HTML5, CSS3, and JavaScript concludes by covering server-side technologies, acting as a guide to the different options available. With insights from renowned experts such as Jason Fried of 37signals, Daniel Burka of Digg and Pownce, and Chris Messina of Citizen Agency, Foundation Website Creation with CSS, XHTML, and JavaScript provides invaluable information applicable to every web project—regardless of size, scope, or budget.
- Published
- 2012
31. Planning and High-Level Design
- Author
-
Joseph R. Lewis, Meitar Moscovitz, Tom Barker, and Jonathan Lane
- Subjects
Value (ethics) ,Site plan ,business.industry ,End user ,Computer science ,media_common.quotation_subject ,Internet privacy ,User story ,Temptation ,Paycheck ,Product (business) ,Environmental design and planning ,business ,media_common - Abstract
It’s entirely by design that we spent the better part of the previous chapter discouraging too much up-front planning. But please don’t call us hypocrites now that we’re offering you an entire chapter that covers the planning and pre-project process. The reality of the situation is that it can be to your advantage to do a little work up front before digging into the development stage. Every project you embark on isn’t going to be crystal clear; you will more than likely end up working outside your comfort zone on more than one occasion. Although it’s easy to get a general feel for most projects, there will undoubtedly be specialized areas in which you will need to consult a subject-matter expert. Your clients may or may not have some idea of what they’re looking for; and even then, after talking it over with them you may come to the realization that their vision of what they want makes absolutely no sense for their end users. The temptation might be there to simply do what the client wants, collect your paycheck, and walk away; however, it’s far more fulfilling to work on projects where you can see the value that will be produced and where people will actually use the product you produce.
- Published
- 2012
- Full Text
- View/download PDF
32. JavaScript Primer
- Author
-
Jonathan Lane, Tom Barker, Joseph R. Lewis, and Meitar Moscovitz
- Published
- 2012
- Full Text
- View/download PDF
33. Closing the Loop with JavaScript
- Author
-
Jonathan Lane, Meitar Moscovitz, Joseph R. Lewis, and Tom Barker
- Subjects
Empty string ,LOOP (programming language) ,Programming language ,Computer science ,media_common.quotation_subject ,Closing (real estate) ,Radio button ,computer.software_genre ,JavaScript ,Break point ,Code snippet ,computer ,media_common ,computer.programming_language - Abstract
We’ve come a long way already with JavaScript. We started out by understanding the roots of the language, then graduated to creating complex logic with it. Next, we began to create our own page-level namespaces; and finally, we learned how to hold all of the functionality that we need in a given page or site.
- Published
- 2012
- Full Text
- View/download PDF
34. Responsive Design
- Author
-
Jonathan Lane, Tom Barker, Joseph R. Lewis, and Meitar Moscovitz
- Published
- 2012
- Full Text
- View/download PDF
35. Using Server-Side Technologies
- Author
-
Meitar Moscovitz, Joseph R. Lewis, Tom Barker, and Jonathan Lane
- Subjects
World Wide Web ,Web server ,Open source ,Virtual machine ,Remote procedure call ,Scripting language ,Computer science ,computer.software_genre ,computer ,Computer-aided technologies ,Server-side - Abstract
It’s pretty hard to find a website these days that doesn’t use some kind of server-side scripting and a database. So many different options are available, from commercial products to open source products, that it can be really daunting to decide which direction you want to go. In the case of web servers, web scripting languages, and databases, the open source alternatives are just as good as (and in some cases, even better than) the commercial options.
- Published
- 2012
- Full Text
- View/download PDF
36. Exploring Fundamental Concepts of CSS
- Author
-
Meitar Moscovitz, Joseph R. Lewis, Tom Barker, and Jonathan Lane
- Subjects
Web browser ,Source code ,Markup language ,Computer science ,Style sheet ,media_common.quotation_subject ,Cascading Style Sheets ,ENCODE ,Rendering (computer graphics) ,World Wide Web ,Web page ,computer ,media_common ,computer.programming_language - Abstract
By now, you should have a solid understanding of how to create web pages using HTML markup. You should understand how to encode semantic meaning into your page content, and you should be familiar with the concept of page elements and how these elements can be nested inside one another to give a page an orderly structure. Finally, you should also understand the basics of how a web browser interprets your HTML source code and determines its rendering. All of these topics were covered in the previous chapter, and all the concepts in this chapter will build on them.
- Published
- 2012
- Full Text
- View/download PDF
37. Afterword: The Business of the Web
- Author
-
Meitar Moscovitz, Joseph R. Lewis, Jonathan Lane, and Tom Barker
- Subjects
World Wide Web ,Work (electrical) ,Personality type ,Web development ,business.industry ,Sociology ,Public relations ,business ,Field (computer science) ,Legal advice - Abstract
This afterword will look at a few different areas on how to best conduct business as it relates to the Web. We’ve known brilliant designers who weren’t very adept at billing. We’ve known excellent developers who have had trouble getting paid because they didn’t work out the terms of an agreement before starting work. Freelancing is a very popular option among people working on the Web. We don’t know whether it’s the nature of the industry or just the personality type of the people who work online, but based on conversations we’ve had at conferences with others working in the field, there seems to be a really high occurrence of people doing side work for themselves among those employed at larger organizations. It’s not uncommon to find individuals who work in completely different fields such as print design or photography (we’ve even met a couple of licensed electricians!) to occasionally work in web development.
- Published
- 2012
- Full Text
- View/download PDF
38. Using WordPress to Jumpstart Development
- Author
-
Jonathan Lane, Joseph R. Lewis, Meitar Moscovitz, and Tom Barker
- Subjects
World Wide Web ,Interactivity ,Development (topology) ,Point (typography) ,Computer science ,Style sheet ,Scratch ,Home page ,JavaScript ,computer ,computer.programming_language - Abstract
Up to this point in the book, we’ve covered a lot of the bases for building a website from scratch. We’ve talked about the most fundamental building blocks of the web and how to combine those together to get up and running with a website. We’ve covered using JavaScript to add some interactivity to our pages and to make things dynamic. We’ve even briefly looked at various server-side languages and systems that can help to make a website a truly dynamic system.
- Published
- 2012
- Full Text
- View/download PDF
39. A Deeper Dive Into JavaScript
- Author
-
Jonathan Lane, Tom Barker, Joseph R. Lewis, and Meitar Moscovitz
- Subjects
World Wide Web ,ComputerSystemsOrganization_COMPUTERSYSTEMIMPLEMENTATION ,Computer science ,ComputerApplications_COMPUTERSINOTHERSYSTEMS ,Construct (python library) ,JavaScript ,computer ,Deep dive ,computer.programming_language - Abstract
Now that we can construct more complex logic with loops and conditional statements, let’s take our knowledge of JavaScript to the next level.
- Published
- 2012
- Full Text
- View/download PDF
40. Giving Your Pages Structure: HTML5
- Author
-
Jonathan Lane, Joseph R. Lewis, Meitar Moscovitz, and Tom Barker
- Subjects
Structure (mathematical logic) ,HTML5 ,Software_GENERAL ,media_common.quotation_subject ,Philosophy ,Reading (process) ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Conversation ,Paragraph ,Emphasis (typography) ,Linguistics ,media_common - Abstract
Start paragraph. Take a minute to imagine what it would be like to have to describe the function of (strong emphasis) everything (end strong emphasis) you’re saying. How (emphasis) irritating (end emphasis) would that be in a conversation? Give it a try: try reading this paragraph out loud. End paragraph.
- Published
- 2012
- Full Text
- View/download PDF
41. Foundation Website Creation with HTML5, CSS3, and JavaScript
- Author
-
Jonathan Lane, Tom Barker, Joseph R. Lewis, and Meitar Moscovitz
- Published
- 2012
- Full Text
- View/download PDF
42. Introducing the Past, Present, and Future of the Web
- Author
-
Tom Barker, Joseph R. Lewis, Jonathan Lane, and Meitar Moscovitz
- Subjects
World Wide Web ,Family member ,Markup language ,Computer science ,Scalable Vector Graphics ,sort ,Cascading Style Sheets ,computer.file_format ,computer ,World wide ,computer.programming_language ,Envelope (motion) - Abstract
Believe it or not, when we were kids the standard way to send a message to a friend or family member was by mail. Not e-mail, mind you, but the physical kind requiring a stamp on the envelope. Fax machines came blazing onto the scene and revolutionized communications because, all of a sudden, you could send a document across the country in a matter of minutes, rather than a number of days. Personal computers were starting to show up in houses, but they generally cost an arm and a leg, and they certainly did not have any sort of way of communicating with the outside world. For the most part, assignments in school were handwritten, unless you had a typewriter at home! It was just the standard.
- Published
- 2012
- Full Text
- View/download PDF
43. Developing CSS3 in Practice: From Design to Deployment
- Author
-
Joseph R. Lewis, Tom Barker, Jonathan Lane, and Meitar Moscovitz
- Subjects
Anchor text ,HTML5 ,Media type ,Markup language ,Web development ,business.industry ,Computer science ,Style sheet ,Cascading Style Sheets ,World Wide Web ,Web page ,ComputingMethodologies_DOCUMENTANDTEXTPROCESSING ,Systems engineering ,business ,computer ,computer.programming_language - Abstract
In the previous two chapters, we talked a lot about the theory and concepts behind standards-based frontend web development. You learned why and how to create structured, semantically meaningful HTML5 markup. You also learned how Cascading Style Sheets work, how web browsers display HTML content by default, and how to apply your own CSS rules to web pages. It’s finally time to bring all your new-found knowledge to bear on a real project and turn your bland, unstyled web page into a beautiful, professionally implemented CSS design.
- Published
- 2012
- Full Text
- View/download PDF
44. Keeping a Project on Track
- Author
-
Jonathan Lane, Joseph R. Lewis, Meitar Moscovitz, and Tom Barker
- Subjects
Scope (project management) ,Staring ,business.industry ,Computer science ,Agile approach ,Public relations ,Project management ,business ,Track (rail transport) ,Simple (philosophy) ,Agile software development - Abstract
Project management doesn’t have to be rocket science. Sure, there are libraries full of books on the topic that make managing projects sound like PhD-worthy material. Trust us, though: when you’re starting out, keeping things simple is the best advice we can offer you! Chances are that the project that you’re currently staring down isn’t overly complex, so don’t let it jump in complexity in your mind. We’re going to take a quick look at a few different ways of managing projects and the three things you should always keep in mind: time, money, and scope (what needs to get done).
- Published
- 2012
- Full Text
- View/download PDF
45. An investigation of the impact of variations of DVH calculation algorithms on DVH dependant radiation therapy plan evaluation metrics
- Author
-
Martin A. Ebert, Angel Kennedy, and Jonathan Lane
- Subjects
History ,Dose-volume histogram ,business.industry ,medicine.medical_treatment ,Sampling (statistics) ,computer.software_genre ,Grid ,Computer Science Applications ,Education ,Radiation therapy ,Voxel ,Plan evaluation ,medicine ,Range (statistics) ,business ,Quality assurance ,Algorithm ,computer ,Simulation ,Mathematics - Abstract
Plan review systems often allow dose volume histogram (DVH) recalculation as part of a quality assurance process for trials. A review of the algorithms provided by a number of systems indicated that they are often very similar. One notable point of variation between implementations is in the location and frequency of dose sampling. This study explored the impact such variations can have on DVH based plan evaluation metrics (Normal Tissue Complication Probability (NTCP), min, mean and max dose), for a plan with small structures placed over areas of high dose gradient. Dose grids considered were exported from the original planning system at a range of resolutions. We found that for the CT based resolutions used in all but one plan review systems (CT and CT with guaranteed minimum number of sampling voxels in the x and y direction) results were very similar and changed in a similar manner with changes in the dose grid resolution despite the extreme conditions. Differences became noticeable however when resolution was increased in the axial (z) direction. Evaluation metrics also varied differently with changing dose grid for CT based resolutions compared to dose grid based resolutions. This suggests that if DVHs are being compared between systems that use a different basis for selecting sampling resolution it may become important to confirm that a similar resolution was used during calculation.
- Published
- 2014
- Full Text
- View/download PDF
46. Foundation Website Creation with CSS, XHTML, and JavaScript
- Author
-
Steve Smith, Jonathan Lane, Steve Smith, and Jonathan Lane
- Subjects
- Internet programming, Web site development, Web sites--Design, Cascading style sheets, XHTML (Document markup language), JavaScript (Computer program language)
- Abstract
Foundation Website Creation with CSS, XHTML, and JavaScript covers the entire process of building a website. This process involves much more than just technical knowledge, and this book provides you with all the information you'll need to understand the concepts behind designing and developing for the Web, as well as the best means to deliver professional, best-practice-based results. There is far more to building a successful website than knowing a little Hypertext Markup Language (HTML). The process starts long before any coding takes place, and this book introduces you to the agile development process, explaining why this method makes so much sense for web projects and how best to implement it. Planning is vital, so you'll also learn how to use techniques such as brainstorming, wireframes, mockups, and prototypes to get your project off to the best possible start and help ensure smooth progress as it develops. An understanding of correct, semantic markup is essential to any web professional, so this book explains how XHTML should be used to structure content so that the markup adheres to current web standards. You'll learn about the wide range of HTML elements available to you, and you'll learn how and when to use them through building example web pages. Without creative use of Cascading Style Sheets (CSS), websites would all look largely the same. CSS gives you the ability to set your website apart from the rest while maintaining the integrity of your markup. You'll learn how CSS works and how to apply styles to your pages, enabling you to realize your design ideas in the browser. JavaScript can be used to make your website easier and more interesting to use. This book provides information on appropriate uses of this technology and introduces the concepts of programming using it. You'll also see how JavaScript works as part of the much-hyped technique Ajax and in turn where Ajax fits into the wider Web 2.0picture. While a website is being built, it needs to be tested across multiple browsers and platforms to ensure that the site works for all users, regardless of ability or disability, and the book explains how best to do these tasks. Then, it discusses the process of launching and maintaining the site so that it will continue to work for all its users throughout its life-cycle. The book concludes by covering server-side technologies, acting as a guide to the different options available and explaining differences between available products. With insights from renowned experts such as Jason Fried of 37signals, Daniel Burka of Digg and Pownce, and Chris Messina of Citizen Agency, this book provides invaluable information applicable to every web project, regardless of size, scope, or budget.
- Published
- 2008
47. From event sequence to grammar
- Author
-
Jonathan Lane and Andrew Pawley
- Subjects
History ,Grammar ,business.industry ,media_common.quotation_subject ,Valency ,Kalam ,Verb ,computer.software_genre ,Linguistics ,Event sequence ,Artificial intelligence ,business ,computer ,Natural language processing ,Generative grammar ,media_common - Published
- 1998
- Full Text
- View/download PDF
48. John Beadle Eades
- Author
-
Jonathan Lane
- Subjects
Gerontology ,Obituaries ,Enthusiasm ,business.industry ,National service ,media_common.quotation_subject ,education ,General Engineering ,North africa ,General Medicine ,Brother ,humanities ,General practice ,General Earth and Planetary Sciences ,Wife ,Medicine ,business ,Order (virtue) ,Classics ,General Environmental Science ,media_common - Abstract
Former general practitioner Eye near Peterborough (b 1922; q Guy's Hospital, London, 1947), died from oesophageal cancer on 12 June 2002. After national service with the Royal Army Medical Corps in north Africa, John entered general practice, initially in the southeast and then to Eye in the Fens, where he remained for more than 30 years. He had an enthusiasm for progress and new developments in diagnosis and treatment and developed excellent relationships with his colleagues in the local hospital. He was made a serving brother of the Order of St John for his work as a teacher and examiner for its Ambulance Brigade, and an honorary life member of the British Red Cross. He leaves a wife, Ann; five daughters; and 11 grandchildren.
- Published
- 2002
- Full Text
- View/download PDF
49. The Period House in the Nineteen-Twenties
- Author
-
Jonathan Lane
- Subjects
Style (visual arts) ,History ,Wright ,Visual Arts and Performing Arts ,Architecture ,Victory ,Economic history ,Plan (drawing) ,Period (music) ,Open plan ,Eclecticism - Abstract
THE history of twentieth-century American residential architecture does not as yet include a full account of the development of dwelling design during what may be called the era of the Period House, the years 1910-1930.1 These decades have been regarded by many historians as a time of unfruitful stagnation in domestic architecture which commenced with the eclipse around 1910 of the groups led by Wright in the Middle West and Bernard Maybeck and the Greene brothers on the Pacific Coast, and continued until the early thirties when the tide began to turn decisively against eclecticism. But while the victory of eclecticism brought to an end the bold experiments of the early years of the century, it did not interrupt the broad process of evolution in the design of suburban dwellings which had long been in progress in the United States. While seeking motifs from abroad in matters of external design, the architects who first began to popularize the Period House in the early 189os had drawn extensively upon the same source as Wright and the other turn-of-the-century pioneers: the wholly American Shingle Style. The planning of the first Period Houses indeed owed almost nothing to the influence of the European past. Rather, the early Period House took over with little modification the most advanced planning of the shingled houses of the eighties, and as far as the treatment of the plan was concerned there was virtually no break between the two styles. But between 1890 and 1930 the design of the Period House was steadily modified, in accordance with the changing needs of the times. Out of this gradual development emerged three important concepts in residential planning which survived the reaction against eclecticism in the early thirties to influence profoundly the further evolution of domestic architecture in the United States-the open plan, the use of rambling one-story designs, and the provision of outdoor living areas. The introduction of these ideas has been generally associated with the work of those architects who rejected
- Published
- 1961
- Full Text
- View/download PDF
50. Quantifying motor recovery after stroke using independent vector analysis and graph-theoretical analysis
- Author
-
Jonathan Laney, Tülay Adalı, Sandy McCombe Waller, and Kelly P. Westlake
- Subjects
IVA ,fMRI ,Stroke ,Graph-theoretical analysis ,Computer applications to medicine. Medical informatics ,R858-859.7 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
The assessment of neuroplasticity after stroke through functional magnetic resonance imaging (fMRI) analysis is a developing field where the objective is to better understand the neural process of recovery and to better target rehabilitation interventions. The challenge in this population stems from the large amount of individual spatial variability and the need to summarize entire brain maps by generating simple, yet discriminating features to highlight differences in functional connectivity. Independent vector analysis (IVA) has been shown to provide superior performance in preserving subject variability when compared with widely used methods such as group independent component analysis. Hence, in this paper, graph-theoretical (GT) analysis is applied to IVA-generated components to effectively exploit the individual subjects' connectivity to produce discriminative features. The analysis is performed on fMRI data collected from individuals with chronic stroke both before and after a 6-week arm and hand rehabilitation intervention. Resulting GT features are shown to capture connectivity changes that are not evident through direct comparison of the group t-maps. The GT features revealed increased small worldness across components and greater centrality in key motor networks as a result of the intervention, suggesting improved efficiency in neural communication. Clinically, these results bring forth new possibilities as a means to observe the neural processes underlying improvements in motor function.
- Published
- 2015
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