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4. Predicting Risk of Infection in Infants with Congenital Diaphragmatic Hernia

Author

Asselin, Jeanette, Durand, David, Dykes, Francine, Evans, Jacquelyn, Murthy, Karna, Padula, Michael, Pallotto, Eugenia, Grover, Theresa, Brozanski, Beverly, Piazza, Anthony, Reber, Kristina, Short, Billie, Porta, Nicolas F.M., Pallotto, Eugenia K., Rintoul, Natalie, Keene, Sarah, Chicoine, Louis, Gien, Jason, Brozanski, Beverly S., Johnson, Yvette R., Haberman, Beth, DiGeronimo, Robert, Zaniletti, Isabella, and Grover, Theresa R.

Published
2018
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5. Extracorporeal membrane oxygenation and bloodstream infection in congenital diaphragmatic hernia

Author

Keene, Sarah, Grover, Theresa R., Murthy, Karna, Pallotto, Eugenia K., Brozanski, Beverly, Gien, Jason, Zaniletti, Isabella, Johnson, Yvette R., Seabrook, Ruth B., Porta, Nicolas F. M., Haberman, Beth, DiGeronimo, Robert, Rintoul, Natalie, and on behalf of the Children’s Hospitals Neonatal Consortium’s (CHNC) Congenital Diaphragmatic Hernia Focus Group

Published
2019
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6. Impact of Optimized Breastfeeding on the Costs of Necrotizing Enterocolitis in Extremely Low Birthweight Infants

Author

Jobe, Alan H., Oh, William, Vohr, Betty R., Walden, Rachel V., Alksninis, Barbara, Hensman, Angelita M., Leonard, Martha R., Noel, Lucy, Leach, Teresa M., Watson, Victoria E., Fanaroff, Avroy A., Walsh, Michele C., Wilson-Costello, Deanne E., Newman, Nancy S., Siner, Bonnie S., Friedman, Harriet G., Donovan, Edward F., Schibler, Kurt, Steichen, Jean J., Alexander, Barbara, Grisby, Cathy, Mersmann, Marcia Worley, Mincey, Holly L., Hessling, Jody, Gratton, Teresa L., Stoll, Barbara J., Adams-Chapman, Ira, Hale, Ellen C., LaRossa, Maureen Mulligan, Carter, Sheena, Higgins, Rosemary D., Wright, Linda L., McClure, Elizabeth M., Poindexter, Brenda B., Lemons, James A., Dusick, Anna M., Kardatzke, Darlene, Lytle, Carolyn, Appel, Diana D., Bohnke, Lon G., Eaken, Greg, Herron, Dianne E., Miller, Lucy C., Richard, Leslie, Wilson, Leslie Dawn, Das, Abhik, Poole, W. Kenneth, Wrage, Lisa Ann, Hastings, Betty K., O'Donnell Auman, Jeanette, Taylor, Sarah, Stevenson, David K., Hintz, Susan R., Ball, M. Bethany, Kohn, Jean G., Baran, Joan M., Lee-Ancajas, Julie C., St. John, Nicholas H., Carlo, Waldemar A., Ambalavanan, Namasivayam, Nelson, Kathleen G., Peralta-Carcelen, Myriam, Bailey, Kirstin J., Biasini, Fred J., Chopko, Stephanie A., Collins, Monica V., Cosby, Shirley S., Phillips, Vivien A., Rector, Richard V., Finer, Neil N., Vaucher, Yvonne E., Anderson, Jack M., Rasmussen, Maynard R., Arnell, Kathy, Demetrio, Clarence, Fuller, Martha G., Henderson, Christopher, Posin, Donna, Bell, Edward F., Colaizy, Tarah T., Bauer, Charles R., Duara, Shahnaz, Worth, Amy Mur, Everett-Thomas, Ruth, Diaz, Alexis N., Mathews, Elaine O., Hamlin-Smith, Kasey, Jean-Gilles, Lisa, Calejo, Maria, Frade, Silvia M., Hiriart-Fajardo, Silvia, Gideon, Yamiley, Korones, Sheldon B., Bada, Henrietta S., Hudson, Tina, Yolton, Kimberly, Williams, Marilyn G., Laptook, Abbot R., Salhab, Walid A., Broyles, R. Sue, Madison, Susie, Hickman, Jackie F., Guzman, Alicia, Adams, Sally S., Madden, Linda A., Heyne, Elizabeth T., Dooley, Cristin, Shankaran, Seetha, Delaney-Black, Virginia, Johnson, Yvette R., Bara, Rebecca, Muran, Geraldine, Kennedy, Deborah, Goldston, Laura A., Ehrenkranz, Richard A., Gettner, Patricia, Konstantino, Monica, Romano, Elaine, Close, Nancy, Gilliam, Walter S., Poulsen, JoAnn, Bartick, Melissa C., Jegier, Briana J., Green, Brittany D., Reinhold, Arnold G., Schaefer, Andrew J., Bogen, Debra L., Schwarz, Eleanor Bimla, and Stuebe, Alison M.

Published
2016
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7. Death or Neurodevelopmental Impairment at 18 to 22 Months Corrected Age in a Randomized Trial of Early Dexamethasone to Prevent Death or Chronic Lung Disease in Extremely Low Birth Weight Infants

Author

Stark, Ann R., Carlo, Waldemar A., Vohr, Betty R., Papile, Lu Ann, Saha, Shampa, Bauer, Charles R., Oh, William, Shankaran, Seetha, Tyson, Jon E., Wright, Linda L., Poole, W. Kenneth, Das, Abhik, Stoll, Barbara J., Fanaroff, Avroy A., Korones, Sheldon B., Ehrenkranz, Richard A., Stevenson, David K., Peralta-Carcelen, Myriam, Wilson-Costello, Deanne E., Bada, Henrietta S., Heyne, Roy J., Johnson, Yvette R., Lee, Kimberly Gronsman, and Steichen, Jean J.

Published
2014
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11. Neurodevelopmental Outcomes of Premature Infants with Severe Respiratory Failure Enrolled in a Randomized Controlled Trial of Inhaled Nitric Oxide

Author

Hintz, Susan R., Van Meurs, Krisa P., Perritt, R., Poole, W. Kenneth, Das, Abhik, Stevenson, David K., Ehrenkranz, Richard A., Lemons, James A., Vohr, Betty R., Heyne, Roy, Childers, David O., Peralta-Carcelen, Myriam, Dusick, Anna, Johnson, Yvette R., Morris, Brenda, Dillard, Robert, Vaucher, Yvonne, Steichen, Jean, Adams-Chapman, Ira, Konduri, Ganesh, Myers, Gary J., de Ungria, Marissa, Tyson, Jon E., and Higgins, Rosemary D.

Published
2007
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12. Real-time polymerase chain reaction for the rapid detection of group B streptococcal colonization in neonates

Author

Natarajan, Girija, Johnson, Yvette R., Zhang, Fan, Chen, Kang Mei, and Worsham, Maria J.

Subjects
Bacterial pneumonia -- Causes of, Bacterial pneumonia -- Diagnosis, Pneumonia -- Causes of, Pneumonia -- Diagnosis, Sepsis -- Causes of, Sepsis -- Diagnosis, Streptococcus agalactiae -- Risk factors
Abstract

BACKGROUND. Group B streptococcal (GBS) infection remains a leading cause of neonatal sepsis. Currently, the management guidelines of neonates born to women with unknown GBS status at delivery are unclear. In this cohort, who undergo at least a 48-hour observation, a rapid method of detection of GBS colonization would allow targeted evaluation and treatment, as well as prevent delayed discharge. OBJECTIVE. The goal of this research was to evaluate the validity of rapid fluorescent real-time polymerase chain reaction in comparison with standard culture to detect GBS colonization in infants born to women whose GBS status is unknown at delivery. DESIGN/METHODS. Neonates at > 32 weeks' gestation born to women whose GBS status was unknown at delivery were included. Samples were obtained from the ear, nose, rectum, and gastric aspirate for immediate culture and real-time polymerase chain reaction after DNA extraction using the LightCycler. Melting point curves were generated, and confirmatory agar gel electrophoresis was performed. RESULTS. The study population (n = 94) had a mean [+ or -] SD gestational age of 38 [+ or -] 2 weeks and birth weight of 3002 [+ or -] 548 g. The rates of GBS colonization by culture were 17% and 51% by real-time polymerase chain reaction. The 4 surface sites had comparable rates of GBS. The overall sensitivities, specificities, and positive and negative predictive values of real-time polymerase chain reaction were: 90%, 80.3%, 28%, and 98.9%. CONCLUSIONS. Real-time polymerase chain reaction resulted in a threefold higher rate of detection of GBS colonization and had an excellent negative predictive value in a cohort of neonates with unknown maternal GBS status at delivery. Thus, real-time polymerase chain reaction would be a useful clinical tool in the management of those infants potentially at risk for invasive GBS infection and would allow earlier discharge for those found to be not at risk. www.pediatrics.org/cgi/doi/10.1542/ peds.2005-1594 doi:10.1542/peds.2005-1594 Key Words group B streptococcus, rapid diagnostic tests, polymerase chain reaction, newborn Abbreviations GBS--group B streptococcus PCR--polymerase chain reaction CI--confidence interval, GROUP B STREPTOCOCCUS (GBS) remains a leading cause of sepsis and pneumonia in the newborn despite the implementation of universal prenatal screening and intrapartum antibiotic prophylaxis in pregnant women. (1) [...]

Published
2006

13. Reopening the debate on corticosteroids

Author

Gordon, Philip V., Doyle, Lex W., Davis, Peter G., Morley, Colin J., McPhee, Andy, Carlin, John B., Fernandes, Caraciolo J., and Johnson, Yvette R.

Abstract

To the Editor.-- Doyle et al (1) are to be congratulated for putting forward a study that highlights the potential of low-dose dexamethasone as a short-term intervention in ventilator-dependent extremely [...]

Published
2006

17. Predictive Models of Neurodevelopmental Outcomes After Neonatal Hypoxic-Ischemic Encephalopathy.

Author

Peeples, Eric S., Rao, Rakesh, Dizon, Maria L. V., Johnson, Yvette R., Joe, Priscilla, Flibotte, John, Hossain, Tanzeema, Smith, Danielle, Hamrick, Shannon, DiGeronimo, Robert, Natarajan, Girija, Kyong-Soon Lee, Yanowitz, Toby D., Mietzsch, Ulrike, Tai-Wei Wu, Maitre, Nathalie L., Pallotto, Eugenia K., Speziale, Mark, Mathur, Amit M., and Zaniletti, Isabella

Published
2021
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18. Predicting Risk of Infection in Infants with Congenital Diaphragmatic Hernia

Author

Murthy, Karna, primary, Porta, Nicolas F.M., additional, Pallotto, Eugenia K., additional, Rintoul, Natalie, additional, Keene, Sarah, additional, Chicoine, Louis, additional, Gien, Jason, additional, Brozanski, Beverly S., additional, Johnson, Yvette R., additional, Haberman, Beth, additional, DiGeronimo, Robert, additional, Zaniletti, Isabella, additional, Grover, Theresa R., additional, Asselin, Jeanette, additional, Durand, David, additional, Dykes, Francine, additional, Evans, Jacquelyn, additional, Murthy, Karna, additional, Padula, Michael, additional, Pallotto, Eugenia, additional, Grover, Theresa, additional, Brozanski, Beverly, additional, Piazza, Anthony, additional, Reber, Kristina, additional, and Short, Billie, additional

Published
2018
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19. Impact of Optimized Breastfeeding on the Costs of Necrotizing Enterocolitis in Extremely Low Birthweight Infants

Author

Colaizy, Tarah T., primary, Bartick, Melissa C., additional, Jegier, Briana J., additional, Green, Brittany D., additional, Reinhold, Arnold G., additional, Schaefer, Andrew J., additional, Bogen, Debra L., additional, Schwarz, Eleanor Bimla, additional, Stuebe, Alison M., additional, Jobe, Alan H., additional, Oh, William, additional, Vohr, Betty R., additional, Walden, Rachel V., additional, Alksninis, Barbara, additional, Hensman, Angelita M., additional, Leonard, Martha R., additional, Noel, Lucy, additional, Leach, Teresa M., additional, Watson, Victoria E., additional, Fanaroff, Avroy A., additional, Walsh, Michele C., additional, Wilson-Costello, Deanne E., additional, Newman, Nancy S., additional, Siner, Bonnie S., additional, Friedman, Harriet G., additional, Donovan, Edward F., additional, Schibler, Kurt, additional, Steichen, Jean J., additional, Alexander, Barbara, additional, Grisby, Cathy, additional, Mersmann, Marcia Worley, additional, Mincey, Holly L., additional, Hessling, Jody, additional, Gratton, Teresa L., additional, Stoll, Barbara J., additional, Adams-Chapman, Ira, additional, Hale, Ellen C., additional, LaRossa, Maureen Mulligan, additional, Carter, Sheena, additional, Higgins, Rosemary D., additional, Wright, Linda L., additional, McClure, Elizabeth M., additional, Poindexter, Brenda B., additional, Lemons, James A., additional, Dusick, Anna M., additional, Kardatzke, Darlene, additional, Lytle, Carolyn, additional, Appel, Diana D., additional, Bohnke, Lon G., additional, Eaken, Greg, additional, Herron, Dianne E., additional, Miller, Lucy C., additional, Richard, Leslie, additional, Wilson, Leslie Dawn, additional, Das, Abhik, additional, Poole, W. Kenneth, additional, Wrage, Lisa Ann, additional, Hastings, Betty K., additional, O'Donnell Auman, Jeanette, additional, Taylor, Sarah, additional, Stevenson, David K., additional, Hintz, Susan R., additional, Ball, M. Bethany, additional, Kohn, Jean G., additional, Baran, Joan M., additional, Lee-Ancajas, Julie C., additional, St. John, Nicholas H., additional, Carlo, Waldemar A., additional, Ambalavanan, Namasivayam, additional, Nelson, Kathleen G., additional, Peralta-Carcelen, Myriam, additional, Bailey, Kirstin J., additional, Biasini, Fred J., additional, Chopko, Stephanie A., additional, Collins, Monica V., additional, Cosby, Shirley S., additional, Phillips, Vivien A., additional, Rector, Richard V., additional, Finer, Neil N., additional, Vaucher, Yvonne E., additional, Anderson, Jack M., additional, Rasmussen, Maynard R., additional, Arnell, Kathy, additional, Demetrio, Clarence, additional, Fuller, Martha G., additional, Henderson, Christopher, additional, Posin, Donna, additional, Bell, Edward F., additional, Colaizy, Tarah T., additional, Bauer, Charles R., additional, Duara, Shahnaz, additional, Worth, Amy Mur, additional, Everett-Thomas, Ruth, additional, Diaz, Alexis N., additional, Mathews, Elaine O., additional, Hamlin-Smith, Kasey, additional, Jean-Gilles, Lisa, additional, Calejo, Maria, additional, Frade, Silvia M., additional, Hiriart-Fajardo, Silvia, additional, Gideon, Yamiley, additional, Korones, Sheldon B., additional, Bada, Henrietta S., additional, Hudson, Tina, additional, Yolton, Kimberly, additional, Williams, Marilyn G., additional, Laptook, Abbot R., additional, Salhab, Walid A., additional, Broyles, R. Sue, additional, Madison, Susie, additional, Hickman, Jackie F., additional, Guzman, Alicia, additional, Adams, Sally S., additional, Madden, Linda A., additional, Heyne, Elizabeth T., additional, Dooley, Cristin, additional, Shankaran, Seetha, additional, Delaney-Black, Virginia, additional, Johnson, Yvette R., additional, Bara, Rebecca, additional, Muran, Geraldine, additional, Kennedy, Deborah, additional, Goldston, Laura A., additional, Ehrenkranz, Richard A., additional, Gettner, Patricia, additional, Konstantino, Monica, additional, Romano, Elaine, additional, Close, Nancy, additional, Gilliam, Walter S., additional, and Poulsen, JoAnn, additional

Published
2016
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21. Association of Hospital Resource Utilization With Neurodevelopmental Outcomes in Neonates With Hypoxic-Ischemic Encephalopathy.

Author

Quinones Cardona, Vilmaris, Rao, Rakesh, Zaniletti, Isabella, Joe, Priscilla, Johnson, Yvette R., DiGeronimo, Robert, Hamrick, Shannon E., Lee, Kyong-Soon, Mietzsch, Ulrike, Natarajan, Girija, Peeples, Eric S., Wu, Tai-Wei, Hossain, Tanzeema, Flibotte, John, Chandel, Amit, Distler, Amy, Shenberger, Jeffrey S., Oghifobibi, Onome, Massaro, An N., and Dizon, Maria L. V.

Published
2023
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22. Cutis laxa and fatal pulmonary hypertension

Author

Brunetti-Pierri, Nicola, primary, Piccolo, Pasquale, additional, Morava, Eva, additional, Wevers, Ron A., additional, McGuirk, Megan, additional, Johnson, Yvette R., additional, Urban, Zsolt, additional, Dishop, Megan K., additional, and Potocki, Lorraine, additional

Published
2011
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24. Postmarketing surveillance for human teratogenicity: A model approach

Author

Chambers, Christina D., primary, Braddock, Stephen R., additional, Briggs, Gerald G., additional, Einarson, Adrienne, additional, Johnson, Yvette R., additional, Miller, Richard K., additional, Polifka, Janine E., additional, Robinson, Luther K., additional, Stepanuk, Kathleen, additional, and Lyons Jones, Kenneth, additional

Published
2001
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26. Selective expression of an acetylcholine receptor–lacZ transgene in synaptic nuclei of adult muscle fibers

Author

Sanes, Joshua R., Johnson, Yvette R., Kotzbauer, Paul T., Mudd, Jacqueline, Hanley, Theresa, Marttnou, Jean-Claude, and Merlie, John P.

Abstract

Acetylcholine receptors (AChRs) are highly concentrated in the postsynaptic membrane at the neuromuscular junction. To investigate mechanisms that lead to the formation or maintenance of this synaptic specialization, we generated transgenic mice in which regulatory elements from the AChR α- or ϵ-subunit genes are linked to a gene for a reporter protein that is targeted to the nucleus (nlacZ). Both transgenes were selectively expressed and developmentally regulated in muscle; nuclei in both extrafusal (ordinary) and intrafusal (spindle) muscle fibers were labeled. Within individual muscle fibers from є-nlacZ mice, nuclei near synaptic sites were nlacZ-positive, whereas extrasynaptic nuclei were nlacZ-negative. In contrast, nlacZ was expressed in both synaptic and extrasynaptic nuclei when under the control of regulatory elements from the AChR α-subunit gene; however, synaptic nuclei were somewhat more intensely stained than extrasynaptic nuclei in a minority of muscle fibers from these mice. Together, our results provide direct evidence for molecular differences between synaptic and extrasynaptic nuclei within a single cytoplasm, and suggest that the motor nerve regulates synapse formation by selectively affecting transcription in synaptic nuclei.

Published
1991
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