155 results on '"Johnson, Benjamin M."'
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2. 6&6 : A Transdisciplinary Approach to Art–Science Collaboration
3. Pretreatment with Yeast-Derived Complex Dietary Polysaccharides Suppresses Gut Inflammation, Alters the Microbiota Composition, and Increases Immune Regulatory Short-Chain Fatty Acid Production in C57BL/6 Mice
4. Gut microbiota differently contributes to intestinal immune phenotype and systemic autoimmune progression in female and male lupus-prone mice
5. The discovery and evaluation of [18F]BMS-986229, a novel macrocyclic peptide PET radioligand for the measurement of PD-L1 expression and in-vivo PD-L1 target engagement
6. Intestinal permeability and inflammatory features of juvenile age correlate with the eventual systemic autoimmunity in lupus‐prone female SWR × NZB F1 (SNF1) mice
7. Abundance and nuclear antigen reactivity of intestinal and fecal Immunoglobulin A in lupus-prone mice at younger ages correlate with the onset of eventual systemic autoimmunity
8. The discovery and evaluation of [18F]BMS-986229, a novel macrocyclic peptide PET radioligand for the measurement of PD-L1 expression and in-vivo PD-L1 target engagement.
9. Intestinal permeability and inflammatory features of juvenile age correlate with the eventual systemic autoimmunity in lupus‐prone female SWR × NZB F1 (SNF1) mice.
10. Screening and Characterization of Reactive Compounds with In Vitro Peptide-Trapping and Liquid Chromatography/High-Resolution Accurate Mass Spectrometry
11. Mechanistic investigation of liver injury induced by BMS-932481, an experimental ɣ-secretase modulator.
12. Novel advances in biotransformation and bioactivation research – 2020 year in review
13. Resensitizing daclatasvir-resistant hepatitis C variants by allosteric modulation of NS5A
14. Discovery and Optimization of Biaryl Alkyl Ethers as a Novel Class of Highly Selective, CNS-Penetrable, and Orally Active Adaptor Protein-2-Associated Kinase 1 (AAK1) Inhibitors for the Potential Treatment of Neuropathic Pain
15. Discovery of (S)-1-((2′,6-Bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine (BMS-986176/LX-9211): A Highly Selective, CNS Penetrable, and Orally Active Adaptor Protein-2 Associated Kinase 1 Inhibitor in Clinical Trials for the Treatment of Neuropathic Pain
16. Gastrin producing syngeneic mesenchymal stem cells protect non-obese diabetic mice from type 1 diabetes
17. Response to Comment on Sofi et al. pH of Drinking Water Influences the Composition of Gut Microbiome and Type 1 Diabetes Incidence. Diabetes 2014;63: 632–644
18. TLR2- and Dectin 1–Associated Innate Immune Response Modulates T-Cell Response to Pancreatic β-Cell Antigen and Prevents Type 1 Diabetes
19. pH of drinking water influences the composition of gut microbiome and type 1 diabetes incidence
20. Synthesis of functionalized derivatives of the gamma-secretase modulator BMS-932481 and identification of its major metabolite
21. Role of Biotransformation Studies in Minimizing Metabolism-Related Liabilities in Drug Discovery
22. Discovery of Orally Active Isofuranones as Potent, Selective Inhibitors of Hematopoetic Progenitor Kinase 1
23. Enhanced antitumor immunity by a novel small molecule HPK1 inhibitor
24. Abundance and nuclear antigen reactivity of intestinal and fecal Immunoglobulin A in lupus-prone mice at younger ages correlate with the onset of eventual systemic autoimmunity
25. Metabolic and Pharmaceutical Aspects of Fluorinated Compounds
26. Gastrin producing syngeneic mesenchymal stem cells protect non-obese diabetic mice from type 1 diabetes.
27. Discovery of Pyridazinone and Pyrazolo[1,5-a]pyridine Inhibitors of C-Terminal Src Kinase
28. Pretreatment with yeast derived complex dietary-polysaccharide leads to suppressed gut inflammation, altered microbiota composition and increased immune regulatory short-chain fatty acid production in C57BL/6 mice
29. Polysaccharide A–Dependent Opposing Effects of Mucosal and Systemic Exposures to Human Gut Commensal Bacteroides fragilis in Type 1 Diabetes
30. Identification of novel glutathione conjugates of terbinafine in liver microsomes and hepatocytes across species
31. Complex dietary polysaccharide modulates gut immune function and microbiota, and promotes protection from autoimmune diabetes
32. Complex dietary-polysaccharide modulates gut immune function and microbiota, and promotes protection from autoimmune diabetes
33. Polysaccharide A-dependent opposing effects of mucosal and systemic exposures to human gut commensalBacteroides fragilisin type 1 diabetes
34. Endoplasmic reticulum stress, autophagic and apoptotic cell death, and immune activation by a natural triterpenoid in human prostate cancer cells
35. Bioactivation of cyclopropyl rings by P450: an observation encountered during the optimisation of a series of hepatitis C virus NS5B inhibitors
36. Development, optimization and implementation of a centralized metabolic soft spot assay
37. Asymmetric Synthesis of the Major Metabolite of a Calcitonin Gene-Related Peptide Receptor Antagonist and Mechanism of Epoxide Hydrogenolysis
38. Discovery of Pyridazinone and Pyrazolo[1,5‑a]pyridine Inhibitors of C‑Terminal Src Kinase.
39. Polysaccharide A-Dependent Opposing Effects of Mucosal and Systemic Exposures to Human Gut Commensal in Type 1 Diabetes.
40. Endoplasmic reticulum stress, autophagic and apoptotic cell death, and immune activation by a natural triterpenoid in human prostate cancer cells.
41. Bioactivation of cyclopropyl rings by P450: an observation encountered during the optimisation of a series of hepatitis C virus NS5B inhibitors.
42. Su1822 Alteration of Murine Intestinal Microbiota by Gastric Helicobacter pylori Infection
43. Identification of Glutathione Conjugates of Acetylene-Containing Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5
44. Electrophilicity of Pyridazine-3-carbonitrile, Pyrimidine-2-carbonitrile, and Pyridine-carbonitrile Derivatives: A Chemical Model To Describe the Formation of Thiazoline Derivatives in Human Liver Microsomes
45. TLR2- and Dectin 1–Associated Innate Immune Response Modulates T-Cell Response to Pancreatic β-Cell Antigen and Prevents Type 1 Diabetes
46. Fungal β-Glucan, a Dectin-1 Ligand, Promotes Protection from Type 1 Diabetes by Inducing Regulatory Innate Immune Response
47. Hepatitis C Virus NS5A Replication Complex Inhibitors: The Discovery of Daclatasvir
48. Abstract 5487: Anti-proliferative, apoptotic and immunological effects of ganoderic acid DM on prostate cancer cells
49. Metabolism of 5-Isopropyl-6-(5-methyl-1,3,4-oxadiazol-2-yl)-N-(2-methyl-1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine (BMS-645737): Identification of an UnusualN-Acetylglucosamine Conjugate in the Cynomolgus Monkey
50. In Vitro Formation of Quinoid Metabolites of the Dietary Supplement Cimicifuga racemosa (Black Cohosh)
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