1. Bone Marrow Mesenchymal Stem Cells as a New Therapeutic Approach for Diabetes Mellitus
- Author
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Luguang Luo, John Z.Q. Luo, and Joseph W Kim
- Subjects
Type 1 diabetes ,business.industry ,Insulin ,medicine.medical_treatment ,Mesenchymal stem cell ,Type 2 diabetes ,medicine.disease ,Bioinformatics ,Regenerative medicine ,Insulin resistance ,Diabetes mellitus ,medicine ,business ,Adult stem cell - Abstract
Adult stem cells have been evaluated as a potential regenerative therapy for many different diseases. One of these is diabetes which is a serious metabolic disorder characterized by either a lack of cellular response to insulin (insulin resistance) (type 2 diabetes) or loss of insulin production (type 1 diabetes). In this chapter, we summarize work performed in our lab, as well as many others, that focus on the ability of bone marrow–derived mesenchymal stem cells to sustain human islet β-cell function and survival and their potential use as a treatment for type 1 and type 2 diabetes.
- Published
- 2019
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